John D. Imig - Publications

Affiliations: 
Medical College of Georgia, Augusta, GA, United States 
Area:
Molecular Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Khan MA, Fish BL, Wahl G, Sharma A, Falck JR, Paudyal M, Moulder JE, Imig JD, Cohen EP. Epoxyeicosatrienoic acid analog mitigates kidney injury in a rat model of radiation nephropathy. Clinical Science (London, England : 1979). PMID 26772189 DOI: 10.1042/CS20150778  0.44
2015 Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA. Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. Purinergic Signalling. PMID 26385692 DOI: 10.1007/s11302-015-9470-7  0.44
2015 Sullivan JC, Imig JD. Reply to "Letter to the editor: 'Concern regarding quantification of urinary nephrin by commercially available ELISA'". American Journal of Physiology. Renal Physiology. 309: F271. PMID 26357487 DOI: 10.1152/ajprenal.00239.2015  0.44
2015 Alánová P, Husková Z, Kopkan L, Sporková A, Jíchová Š, Neckář J, Imig JD, Klevstig M, Kolář F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovský V, et al. Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats. Vascular Pharmacology. 73: 45-56. PMID 26304700 DOI: 10.1016/j.vph.2015.08.013  0.44
2015 Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ. Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. American Journal of Physiology. Renal Physiology. 308: F131-9. PMID 25377915 DOI: 10.1152/ajprenal.00531.2014  0.44
2015 Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 26: 597-610. PMID 25071086 DOI: 10.1681/ASN.2013090980  0.44
2014 Sporková A, Jíchová S, Husková Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats. Clinical and Experimental Pharmacology & Physiology. 41: 1003-13. PMID 25224811 DOI: 10.1111/1440-1681.12310  0.44
2014 Kim J, Imig JD, Yang J, Hammock BD, Padanilam BJ. Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation. American Journal of Physiology. Renal Physiology. 307: F971-80. PMID 25164080 DOI: 10.1152/ajprenal.00256.2014  0.44
2014 Kujal P, ?ertíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, ?ervenka L. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and Experimental Pharmacology & Physiology. 41: 227-37. PMID 24471737 DOI: 10.1111/1440-1681.12204  0.44
2014 Cabral PD, Hong NJ, Hye Khan MA, Ortiz PA, Beierwaltes WH, Imig JD, Garvin JL. Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II. Hypertension. 63: e68-73. PMID 24379189 DOI: 10.1161/HYPERTENSIONAHA.113.02564  0.44
2013 Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension. Journal of Cardiovascular Pharmacology. 62: 285-97. PMID 23676336 DOI: 10.1097/FJC.0b013e318298e460  0.44
2013 Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, ?ervenka L. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. Journal of Hypertension. 31: 321-32. PMID 23307303 DOI: 10.1097/HJH.0b013e32835b50aa  0.44
2013 Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Clinical and Experimental Pharmacology & Physiology. 40: 273-81. PMID 23039246 DOI: 10.1111/1440-1681.12018  0.44
2012 Imig JD, Walsh KA, Hye Khan MA, Nagasawa T, Cherian-Shaw M, Shaw SM, Hammock BD. Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats. Experimental Biology and Medicine (Maywood, N.J.). 237: 1402-12. PMID 23354399 DOI: 10.1258/ebm.2012.012225  0.44
2012 Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Červenka L. Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension. Kidney & Blood Pressure Research. 35: 595-607. PMID 22948718 DOI: 10.1159/000339883  0.44
2012 Neckár J, Kopkan L, Husková Z, Kolář F, Papoušek F, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Malý J, Netuka I, Ošťádal B, Červenka L. Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-I-ylureido)cyclohexyloxy] benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension Clinical Science. 122: 513-525. PMID 22324471 DOI: 10.1042/CS20110622  0.44
2012 Bukhari IA, Shah AJ, Gauthier KM, Walsh KA, Koduru SR, Imig JD, Falck JR, Campbell WB. 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1574-83. PMID 22307677 DOI: 10.1152/ajpheart.01122.2011  0.44
2011 Elmarakby AA, Faulkner J, Al-Shabrawey M, Wang MH, Maddipati KR, Imig JD. Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R1307-17. PMID 21832210 DOI: 10.1152/ajpregu.00759.2010  0.44
2011 Gauthier KM, Olson L, Harder A, Isbell M, Imig JD, Gutterman DD, Falck JR, Campbell WB. Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles. American Journal of Physiology. Renal Physiology. 301: F765-72. PMID 21753077 DOI: 10.1152/ajprenal.00201.2011  0.44
2011 Honetschlägerová Z, Sporková A, Kopkan L, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Chábová VC, Tesař V, Cervenka L. Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats. Journal of Hypertension. 29: 1590-601. PMID 21720266 DOI: 10.1097/HJH.0b013e328349062f  0.44
2011 Luria A, Bettaieb A, Xi Y, Shieh GJ, Liu HC, Inoue H, Tsai HJ, Imig JD, Haj FG, Hammock BD. Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 9038-43. PMID 21571638 DOI: 10.1073/pnas.1103482108  0.44
2011 Sporková A, Kopkan L, Varcabová S, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Červenka L. Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300: 1468-1475. PMID 21411763 DOI: 10.1152/ajpregu.00215.2010  0.44
2011 Honetschlägerová Z, Z Husková Z, Vaňourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Červenka L, Kopkan L. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. The Journal of Physiology. 589: 207-19. PMID 21078594 DOI: 10.1113/jphysiol.2010.199505  0.44
2010 Imig JD, Elmarakby A, Nithipatikom K, Wei S, Capdevila JH, Tuniki VR, Sangras B, Anjaiah S, Manthati VL, Sudarshan Reddy D, Falck JR. Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions. Frontiers in Physiology. 1: 157. PMID 21423396 DOI: 10.3389/fphys.2010.00157  0.44
2010 Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, et al. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3770-81. PMID 20495177 DOI: 10.1096/fj.10-160119  0.44
2010 Simpkins AN, Rudic RD, Roy S, Tsai HJ, Hammock BD, Imig JD. Soluble epoxide hydrolase inhibition modulates vascular remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 298: H795-806. PMID 20035028 DOI: 10.1152/ajpheart.00543.2009  0.44
2010 Knight SF, Yuan J, Roy S, Imig JD. Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension. American Journal of Physiology. Renal Physiology. 298: F86-94. PMID 19906952 DOI: 10.1152/ajprenal.00351.2009  0.44
2010 Elmarakby AA, Imig JD. Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats. Clinical Science (London, England : 1979). 118: 291-301. PMID 19728860 DOI: 10.1042/CS20090395  0.44
2009 Manhiani M, Quigley JE, Knight SF, Tasoobshirazi S, Moore T, Brands MW, Hammock BD, Imig JD. Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension. American Journal of Physiology. Renal Physiology. 297: F740-8. PMID 19553349 DOI: 10.1152/ajprenal.00098.2009  0.44
2009 Simpkins AN, Rudic RD, Schreihofer DA, Roy S, Manhiani M, Tsai HJ, Hammock BD, Imig JD. Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. The American Journal of Pathology. 174: 2086-95. PMID 19435785 DOI: 10.2353/ajpath.2009.080544  0.44
2009 Quigley JE, Elmarakby AA, Knight SF, Manhiani MM, Stepp DW, Olearzcyk JJ, Imig JD. Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension. Clinical and Experimental Pharmacology & Physiology. 36: 724-8. PMID 19207724 DOI: 10.1111/j.1440-1681.2009.05139.x  0.44
2009 Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD. Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clinical Science (London, England : 1979). 116: 61-70. PMID 18459944 DOI: 10.1042/CS20080039  0.44
2008 Said NA, Elmarakby AA, Imig JD, Fulton DJ, Motamed K. SPARC ameliorates ovarian cancer-associated inflammation. Neoplasia (New York, N.Y.). 10: 1092-104. PMID 18813349  0.44
2008 Athirakul K, Bradbury JA, Graves JP, DeGraff LM, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, et al. Increased blood pressure in mice lacking cytochrome P450 2J5. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4096-108. PMID 18716027 DOI: 10.1096/fj.08-114413  0.44
2008 Knight SF, Quigley JE, Yuan J, Roy SS, Elmarakby A, Imig JD. Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet. Hypertension. 51: 352-9. PMID 18158349 DOI: 10.1161/HYPERTENSIONAHA.107.099499  0.44
2008 Elmarakby AA, Quigley JE, Imig JD, Pollock JS, Pollock DM. TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R76-83. PMID 17989143 DOI: 10.1152/ajpregu.00466.2007  0.44
2007 Said N, Socha MJ, Olearczyk JJ, Elmarakby AA, Imig JD, Motamed K. Normalization of the ovarian cancer microenvironment by SPARC. Molecular Cancer Research : McR. 5: 1015-30. PMID 17951402 DOI: 10.1158/1541-7786.MCR-07-0001  0.44
2007 Elmarakby AA, Quigley JE, Olearczyk JJ, Sridhar A, Cook AK, Inscho EW, Pollock DM, Imig JD. Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension. 50: 1069-76. PMID 17938380 DOI: 10.1161/HYPERTENSIONAHA.107.098806  0.44
2007 Socha MJ, Manhiani M, Said N, Imig JD, Motamed K. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension. The American Journal of Pathology. 171: 1104-12. PMID 17717147 DOI: 10.2353/ajpath.2007.061273  0.4
2007 Knight SF, Imig JD. Obesity, insulin resistance, and renal function. Microcirculation (New York, N.Y. : 1994). 14: 349-62. PMID 17613807 DOI: 10.1080/10739680701283018  0.44
2007 Manhiani MM, Quigley JE, Socha MJ, Motamed K, Imig JD. IL6 suppression provides renal protection independent of blood pressure in a murine model of salt-sensitive hypertension. Kidney & Blood Pressure Research. 30: 195-202. PMID 17575466 DOI: 10.1159/000104094  0.44
2007 Kang KT, Sullivan JC, Sasser JM, Imig JD, Pollock JS. Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats. Hypertension. 49: 893-901. PMID 17309950 DOI: 10.1161/01.HYP.0000259669.40991.1e  0.44
2007 Elmarakby AA, Williams JM, Imig JD, Pollock JS, Pollock DM. Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension. Vascular Pharmacology. 46: 144-51. PMID 17112788 DOI: 10.1016/j.vph.2006.09.004  0.44
2006 Zhao X, Quigley JE, Yuan J, Wang MH, Zhou Y, Imig JD. PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2187-95. PMID 16501022 DOI: 10.1152/ajpheart.00937.2005  0.44
2006 Elmarakby AA, Quigley JE, Pollock DM, Imig JD. Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension. Hypertension. 47: 557-62. PMID 16415373 DOI: 10.1161/01.HYP.0000198545.01860.90  0.44
2006 Jin L, Foss CE, Zhao X, Mills TM, Wang MH, McCluskey LP, Yaddanapud GS, Falck JR, Imig JD, Webb RC. Cytochrome P450 epoxygenases provide a novel mechanism for penile erection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 539-41. PMID 16415108 DOI: 10.1096/fj.05-4341fje  0.44
2005 Inscho EW, Imig JD, Cook AK, Pollock DM. ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. British Journal of Pharmacology. 146: 1019-26. PMID 16231007 DOI: 10.1038/sj.bjp.0706412  0.44
2005 Zhao X, Cook AK, Field M, Edwards B, Zhang S, Zhang Z, Pollock JS, Imig JD, Inscho EW. Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension. Hypertension. 46: 562-8. PMID 16116048 DOI: 10.1161/01.HYP.0000179584.39937.41  0.44
2005 Pollock DM, Jenkins JM, Cook AK, Imig JD, Inscho EW. L-type calcium channels in the renal microcirculatory response to endothelin. American Journal of Physiology. Renal Physiology. 288: F771-7. PMID 15547114 DOI: 10.1152/ajprenal.00315.2004  0.44
2005 Zhao X, Dey A, Romanko OP, Stepp DW, Wang MH, Zhou Y, Jin L, Pollock JS, Webb RC, Imig JD. Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R188-96. PMID 15345471 DOI: 10.1152/ajpregu.00018.2004  0.44
2004 Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obesity Research. 12: 1278-89. PMID 15340111 DOI: 10.1038/oby.2004.162  0.44
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