Dana E. Selley - Publications

Pharmacology & Toxicology Virginia Commonwealth University, Richmond, VA, United States 
Pharmacology, Molecular Biology

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Selley DE, Lazenka MF, Sim-Selley LJ, Secor McVoy JR, Potter DN, Chartoff EH, Carlezon WA, Negus SS. Attenuated dopamine receptor signaling in nucleus accumbens core in a rat model of chemically-induced neuropathy. Neuropharmacology. 166: 107935. PMID 31917153 DOI: 10.1016/j.neuropharm.2020.107935  0.44
2018 Kota D, Alajaji M, Bagdas D, Selley DE, Sim-Selley LJ, Imad Damaj M. Early adolescent nicotine exposure affects later-life hippocampal mu-opioid receptors activity and morphine reward but not physical dependence in male mice. Pharmacology, Biochemistry, and Behavior. PMID 30125591 DOI: 10.1016/j.pbb.2018.08.006  0.44
2018 Sim-Selley LJ, Wilkerson JL, Burston JJ, Hauser KF, McLane V, Welch SP, Lichtman AH, Selley DE. Differential Tolerance to FTY720-induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of S1P Receptor Adaptation. The Journal of Pharmacology and Experimental Therapeutics. PMID 29945931 DOI: 10.1124/jpet.118.248260  0.44
2017 Lazenka MF, Kang M, De DD, Selley DE, Sim-Selley LJ. Δ(9)-Tetrahydrocannabinol Experience Influences ΔFosB and Downstream Gene Expression in Prefrontal Cortex. Cannabis and Cannabinoid Research. 2: 224-234. PMID 29082320 DOI: 10.1089/can.2017.0022  0.44
2016 Grim TW, Morales AJ, Gonek MM, Wiley JL, Thomas BF, Endres GW, Sim-Selley LJ, Selley DE, Negus SS, Lichtman AH. Stratification of cannabinoid 1 receptor (CB1R) agonist efficacy: Manipulation of CB1R density through use of transgenic mice reveals congruence between in vivo and in vitro assays. The Journal of Pharmacology and Experimental Therapeutics. PMID 27535976 DOI: 10.1124/jpet.116.233163  0.44
2016 Hahn YK, Paris JJ, Lichtman AH, Hauser KF, Sim-Selley LJ, Selley DE, Knapp PE. Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain. Neurobiology of Disease. PMID 26845176 DOI: 10.1016/j.nbd.2016.01.014  0.44
2016 Alajaji M, Lazenka MF, Kota D, Wise LE, YOUnis RM, Carroll FI, Levine A, Selley DE, Sim-Selley LJ, Damaj MI. Early adolescent nicotine exposure affects later-life cocaine reward in mice. Neuropharmacology. PMID 26808314 DOI: 10.1016/j.neuropharm.2016.01.032  0.44
2015 Viader A, Blankman JL, Zhong P, Liu X, Schlosburg JE, Joslyn CM, Liu QS, Tomarchio AJ, Lichtman AH, Selley DE, Sim-Selley LJ, Cravatt BF. Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action. Cell Reports. PMID 26212325 DOI: 10.1016/j.celrep.2015.06.075  0.44
2015 Lazenka MF, Tomarchio A, Lichtman AH, Greengard P, Flajolet M, Selley DE, Sim-Selley LJ. Role of dopamine type 1 receptors and DARPP-32 in Δ9-THC-mediated induction of ΔFosB in the mouse forebrain. The Journal of Pharmacology and Experimental Therapeutics. PMID 26099530 DOI: 10.1124/jpet.115.224428  0.44
2015 Ghosh S, Kinsey SG, Liu QS, Hruba L, McMahon LR, Grim TW, Merritt CR, Wise LE, Abdullah RA, Selley DE, Sim-Selley LJ, Cravatt BF, Lichtman AH. Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice. The Journal of Pharmacology and Experimental Therapeutics. 354: 111-20. PMID 25998048 DOI: 10.1124/jpet.115.222851  0.44
2015 Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Mosier PD, Kellogg GE, Dewey WL, Selley DE, Zhang Y. Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorganic & Medicinal Chemistry. 23: 1701-15. PMID 25783191 DOI: 10.1016/j.bmc.2015.02.055  0.44
2015 Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE. Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Molecular Pharmacology. 87: 747-65. PMID 25657338 DOI: 10.1124/mol.114.096495  0.44
2015 Blume LC, Eldeeb K, Bass CE, Selley DE, Howlett AC. Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells. Cellular Signalling. 27: 716-26. PMID 25446256 DOI: 10.1016/j.cellsig.2014.11.006  0.44
2014 Lazenka MF, David BG, Lichtman AH, Nestler EJ, Selley DE, Sim-Selley LJ. Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions. Biochemical Pharmacology. 91: 380-9. PMID 25093286 DOI: 10.1016/j.bcp.2014.07.024  0.44
2014 Naydenov AV, Horne EA, Cheah CS, Swinney K, Hsu KL, Cao JK, Marrs WR, Blankman JL, Tu S, Cherry AE, Fung S, Wen A, Li W, Saporito MS, Selley DE, et al. ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice. Neuron. 83: 361-71. PMID 25033180 DOI: 10.1016/j.neuron.2014.06.030  0.44
2014 Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH. Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 350: 196-204. PMID 24849924 DOI: 10.1124/jpet.114.212753  0.44
2014 Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K. Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5152-63. PMID 24719095 DOI: 10.1523/JNEUROSCI.3445-12.2014  0.44
2014 Emery SM, Alotaibi MR, Tao Q, Selley DE, Lichtman AH, Gewirtz DA. Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 348: 293-302. PMID 24259678 DOI: 10.1124/jpet.113.205120  0.44
2014 Lazenka MF, Selley DE, Sim-Selley LJ. ΔFosB induction correlates inversely with CB₁ receptor desensitization in a brain region-dependent manner following repeated Δ⁹-THC administration. Neuropharmacology. 77: 224-33. PMID 24090766 DOI: 10.1016/j.neuropharm.2013.09.019  0.44
2013 Yuan Y, Zaidi SA, Elbegdorj O, Aschenbach LC, Li G, Stevens DL, Scoggins KL, Dewey WL, Selley DE, Zhang Y. Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivity. Journal of Medicinal Chemistry. 56: 9156-69. PMID 24144240 DOI: 10.1021/jm4012214  0.44
2013 Zaidi SA, Arnatt CK, He H, Selley DE, Mosier PD, Kellogg GE, Zhang Y. Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: Application of the 'message-address' concept in development of mu opioid receptor selective antagonists Bioorganic and Medicinal Chemistry. 21: 6405-6413. PMID 24055076 DOI: 10.1016/j.bmc.2013.08.042  0.44
2013 Selley DE, Welch SP, Sim-Selley LJ. Sphingosine lysolipids in the CNS: endogenous cannabinoid antagonists or a parallel pain modulatory system? Life Sciences. 93: 187-93. PMID 23782998 DOI: 10.1016/j.lfs.2013.06.004  0.44
2013 Yuan Y, Arnatt CK, El-Hage N, Dever SM, Jacob JC, Selley DE, Hauser KF, Zhang Y. A Bivalent Ligand Targeting the Putative Mu Opioid Receptor and Chemokine Receptor CCR5 Heterodimers: Binding Affinity versus Functional Activities. Medchemcomm. 4: 847-851. PMID 23682308 DOI: 10.1039/C3MD00080J  0.44
2013 Kinsey SG, Wise LE, Ramesh D, Abdullah R, Selley DE, Cravatt BF, Lichtman AH. Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects. The Journal of Pharmacology and Experimental Therapeutics. 345: 492-501. PMID 23412396 DOI: 10.1124/jpet.112.201426  0.44
2013 Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC. Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and δ opioid systems. Journal of Neurochemistry. 124: 808-20. PMID 23286559 DOI: 10.1111/jnc.12139  0.44
2012 Yuan Y, Elbegdorj O, Chen J, Akubathini SK, Zhang F, Stevens DL, Beletskaya IO, Scoggins KL, Zhang Z, Gerk PM, Selley DE, Akbarali HI, Dewey WL, Zhang Y. Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents. Journal of Medicinal Chemistry. 55: 10118-29. PMID 23116124 DOI: 10.1021/jm301247n  0.44
2012 Welch SP, Sim-Selley LJ, Selley DE. Sphingosine-1-phosphate receptors as emerging targets for treatment of pain. Biochemical Pharmacology. 84: 1551-62. PMID 22971335 DOI: 10.1016/j.bcp.2012.08.010  0.44
2012 Nguyen PT, Schmid CL, Raehal KM, Selley DE, Bohn LM, Sim-Selley LJ. β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner. Biological Psychiatry. 71: 714-24. PMID 22264443 DOI: 10.1016/j.biopsych.2011.11.027  0.44
2012 Wiley JL, Selley DE, Wang P, Kottani R, Gadthula S, Mahadeven A. 3-Substituted pyrazole analogs of the cannabinoid type 1 (CB₁) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CB₁, non-CBâ‚‚ mechanism. The Journal of Pharmacology and Experimental Therapeutics. 340: 433-44. PMID 22085649 DOI: 10.1124/jpet.111.187815  0.44
2011 Yuan Y, Li G, He H, Stevens DL, Kozak P, Scoggins KL, Mitra P, Gerk PM, Selley DE, Dewey WL, Zhang Y. Characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as novel leads to development of mu opioid receptor selective antagonists. Acs Chemical Neuroscience. 2: 346-51. PMID 22816021 DOI: 10.1021/cn2000348  0.44
2011 Sim-Selley LJ, Cassidy MP, Sparta A, Zachariou V, Nestler EJ, Selley DE. Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens. Neuropharmacology. 61: 1470-6. PMID 21907220 DOI: 10.1016/j.neuropharm.2011.08.046  0.44
2011 Hoot MR, Sim-Selley LJ, Selley DE, Scoggins KL, Dewey WL. Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus. Brain Research. 1406: 1-7. PMID 21762883 DOI: 10.1016/j.brainres.2011.06.023  0.44
2011 Wise LE, Varvel SA, Selley DE, Wiebelhaus JM, Long KA, Middleton LS, Sim-Selley LJ, Lichtman AH. delta(9)-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory. Psychopharmacology. 217: 485-94. PMID 21559804 DOI: 10.1007/s00213-011-2305-5  0.44
2011 Kinsey SG, Mahadevan A, Zhao B, Sun H, Naidu PS, Razdan RK, Selley DE, Imad Damaj M, Lichtman AH. The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects. Neuropharmacology. 60: 244-51. PMID 20849866 DOI: 10.1016/j.neuropharm.2010.09.004  0.44
2010 Huffman JW, Hepburn SA, Lyutenko N, Thompson AL, Wiley JL, Selley DE, Martin BR. 1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-Δ(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor. Bioorganic & Medicinal Chemistry. 18: 7809-15. PMID 20943404 DOI: 10.1016/j.bmc.2010.09.061  0.44
2010 Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, et al. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nature Neuroscience. 13: 1113-9. PMID 20729846 DOI: 10.1038/nn.2616  0.44
2010 Burston JJ, Wiley JL, Craig AA, Selley DE, Sim-Selley LJ. Regional enhancement of cannabinoid CB₁ receptor desensitization in female adolescent rats following repeated Delta-tetrahydrocannabinol exposure. British Journal of Pharmacology. 161: 103-12. PMID 20718743 DOI: 10.1111/j.1476-5381.2010.00870.x  0.44
2010 Smith TH, Sim-Selley LJ, Selley DE. Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery? British Journal of Pharmacology. 160: 454-66. PMID 20590557 DOI: 10.1111/j.1476-5381.2010.00777.x  0.44
2010 Nguyen PT, Selley DE, Sim-Selley LJ. Statistical Parametric Mapping reveals ligand and region-specific activation of G-proteins by CB1 receptors and non-CB1 sites in the 3D reconstructed mouse brain Neuroimage. 52: 1243-1251. PMID 20451624 DOI: 10.1016/j.neuroimage.2010.04.259  0.44
2010 Hoot MR, Sim-Selley LJ, Poklis JL, Abdullah RA, Scoggins KL, Selley DE, Dewey WL. Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. Brain Research. 1339: 18-25. PMID 20380816 DOI: 10.1016/j.brainres.2010.03.105  0.44
2010 Falenski KW, Thorpe AJ, Schlosburg JE, Cravatt BF, Abdullah RA, Smith TH, Selley DE, Lichtman AH, Sim-Selley LJ. FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1775-87. PMID 20357755 DOI: 10.1038/npp.2010.44  0.44
2009 Sim-Selley LJ, Goforth PB, Mba MU, Macdonald TL, Lynch KR, Milstien S, Spiegel S, Satin LS, Welch SP, Selley DE. Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS. Journal of Neurochemistry. 110: 1191-202. PMID 19493165 DOI: 10.1111/j.1471-4159.2009.06202.x  0.44
2009 Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists. Journal of Medicinal Chemistry. 52: 1416-27. PMID 19199782 DOI: 10.1021/jm801272c  0.44
2009 Long JZ, Li W, Booker L, Burston JJ, Kinsey SG, Schlosburg JE, Pavón FJ, Serrano AM, Selley DE, Parsons LH, Lichtman AH, Cravatt BF. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nature Chemical Biology. 5: 37-44. PMID 19029917 DOI: 10.1038/nchembio.129  0.44
2009 Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Corrections to design, synthesis, and biological evaluation of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as μ opioid receptor selective antagonists (Journal of Medicinal Chemistry (2009) 52, (1416) DOI 10.1021/jm801272c) Journal of Medicinal Chemistry. 52: 8057. DOI: 10.1021/jm9016224  0.44
2008 Wiley JL, Kendler SH, Burston JJ, Howard DR, Selley DE, Sim-Selley LJ. Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats. Neuropharmacology. 55: 1183-90. PMID 18708079 DOI: 10.1016/j.neuropharm.2008.07.026  0.44
2008 Burston JJ, Sim-Selley LJ, Harloe JP, Mahadevan A, Razdan RK, Selley DE, Wiley JL. N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase. The Journal of Pharmacology and Experimental Therapeutics. 327: 546-53. PMID 18682568 DOI: 10.1124/jpet.108.141382  0.44
2008 Perrotti LI, Weaver RR, Robison B, Renthal W, Maze I, Yazdani S, Elmore RG, Knapp DJ, Selley DE, Martin BR, Sim-Selley L, Bachtell RK, Self DW, Nestler EJ. Distinct patterns of DeltaFosB induction in brain by drugs of abuse. Synapse (New York, N.Y.). 62: 358-69. PMID 18293355 DOI: 10.1002/syn.20500  0.44
2008 McKinney DL, Cassidy MP, Collier LM, Martin BR, Wiley JL, Selley DE, Sim-Selley LJ. Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 324: 664-73. PMID 17967938 DOI: 10.1124/jpet.107.130328  0.44
2007 Niehaus JL, Liu Y, Wallis KT, Egertová M, Bhartur SG, Mukhopadhyay S, Shi S, He H, Selley DE, Howlett AC, Elphick MR, Lewis DL. CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a. Molecular Pharmacology. 72: 1557-66. PMID 17895407 DOI: 10.1124/mol.107.039263  0.44
2007 Kalvass JC, Olson ER, Cassidy MP, Selley DE, Pollack GM. Pharmacokinetics and pharmacodynamics of seven opioids in P-glycoprotein-competent mice: assessment of unbound brain EC50,u and correlation of in vitro, preclinical, and clinical data. The Journal of Pharmacology and Experimental Therapeutics. 323: 346-55. PMID 17646430 DOI: 10.1124/jpet.107.119560  0.44
2007 Smith PA, Selley DE, Sim-Selley LJ, Welch SP. Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors. European Journal of Pharmacology. 571: 129-37. PMID 17603035 DOI: 10.1016/j.ejphar.2007.06.001  0.44
2007 Sim-Selley LJ, Scoggins KL, Cassidy MP, Smith LA, Dewey WL, Smith FL, Selley DE. Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance. British Journal of Pharmacology. 151: 1324-33. PMID 17572699 DOI: 10.1038/sj.bjp.0707328  0.44
2006 Sim-Selley LJ, Schechter NS, Rorrer WK, Dalton GD, Hernandez J, Martin BR, Selley DE. Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration. Molecular Pharmacology. 70: 986-96. PMID 16760363 DOI: 10.1124/mol.105.019612  0.44
2006 Paugh SW, Cassidy MP, He H, Milstien S, Sim-Selley LJ, Spiegel S, Selley DE. Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, interact with the CB1 cannabinoid receptor. Molecular Pharmacology. 70: 41-50. PMID 16571654 DOI: 10.1124/mol.105.020552  0.44
2006 Zachariou V, Bolanos CA, Selley DE, Theobald D, Cassidy MP, Kelz MB, Shaw-Lutchman T, Berton O, Sim-Selley LJ, Dileone RJ, Kumar A, Nestler EJ. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature Neuroscience. 9: 205-11. PMID 16415864 DOI: 10.1038/nn1636  0.44
2005 Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, Cassidy MP, Wiley JL, Martin BR. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorganic & Medicinal Chemistry Letters. 15: 4110-3. PMID 16005223 DOI: 10.1016/j.bmcl.2005.06.008  0.44
2005 Huffman JW, Zengin G, Wu MJ, Lu J, Hynd G, Bushell K, Thompson AL, Bushell S, Tartal C, Hurst DP, Reggio PH, Selley DE, Cassidy MP, Wiley JL, Martin BR. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists. Bioorganic & Medicinal Chemistry. 13: 89-112. PMID 15582455 DOI: 10.1016/j.bmc.2004.09.050  0.44
2004 Cichewicz DL, Cox ML, Welch SP, Selley DE, Sim-Selley LJ. Mu and delta opioid-stimulated [35S]GTP gamma S binding in brain and spinal cord of polyarthritic rats. European Journal of Pharmacology. 504: 33-8. PMID 15507218 DOI: 10.1016/j.ejphar.2004.09.050  0.44
2004 Schwindinger WF, Giger KE, Betz KS, Stauffer AM, Sunderlin EM, Sim-Selley LJ, Selley DE, Bronson SK, Robishaw JD. Mice with deficiency of G protein gamma3 are lean and have seizures. Molecular and Cellular Biology. 24: 7758-68. PMID 15314181 DOI: 10.1128/MCB.24.17.7758-7768.2004  0.44
2004 Selley DE, Cassidy MP, Martin BR, Sim-Selley LJ. Long-term administration of Delta9-tetrahydrocannabinol desensitizes CB1-, adenosine A1-, and GABAB-mediated inhibition of adenylyl cyclase in mouse cerebellum. Molecular Pharmacology. 66: 1275-84. PMID 15286206 DOI: 10.1124/mol.104.000604  0.44
2004 Martin BR, Sim-Selley LJ, Selley DE. Signaling pathways involved in the development of cannabinoid tolerance. Trends in Pharmacological Sciences. 25: 325-30. PMID 15165748 DOI: 10.1016/j.tips.2004.04.005  0.44
2004 Thompson CM, Wojno H, Greiner E, May EL, Rice KC, Selley DE. Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors. The Journal of Pharmacology and Experimental Therapeutics. 308: 547-54. PMID 14600248 DOI: 10.1124/jpet.103.058602  0.44
2003 Zachariou V, Georgescu D, Sanchez N, Rahman Z, DiLeone R, Berton O, Neve RL, Sim-Selley LJ, Selley DE, Gold SJ, Nestler EJ. Essential role for RGS9 in opiate action. Proceedings of the National Academy of Sciences of the United States of America. 100: 13656-61. PMID 14595021 DOI: 10.1073/pnas.2232594100  0.44
2003 Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, et al. RGS9 modulates dopamine signaling in the basal ganglia. Neuron. 38: 941-52. PMID 12818179 DOI: 10.1016/S0896-6273(03)00321-0  0.44
2003 Selley DE, Herbert JT, Morgan D, Cook CD, Picker MJ, Sim-Selley LJ. Effect of strain and sex on mu opioid receptor-mediated G-protein activation in rat brain. Brain Research Bulletin. 60: 201-8. PMID 12754081 DOI: 10.1016/S0361-9230(03)00014-5  0.44
2002 Sim-Selley LJ, Sharpe AL, Vogt LJ, Brunk LK, Selley DE, Samson HH. Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity. Alcoholism, Clinical and Experimental Research. 26: 688-94. PMID 12045478 DOI: 10.1111/j.1530-0277.2002.tb02592.x  0.44
2001 Selley DE, Cao CC, Sexton T, Schwegel JA, Martin TJ, Childers SR. mu Opioid receptor-mediated G-protein activation by heroin metabolites: evidence for greater efficacy of 6-monoacetylmorphine compared with morphine. Biochemical Pharmacology. 62: 447-55. PMID 11448454 DOI: 10.1016/S0006-2952(01)00689-X  0.44
2001 Selley DE, Rorrer WK, Breivogel CS, Zimmer AM, Zimmer A, Martin BR, Sim-Selley LJ. Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G-protein activation. Journal of Neurochemistry. 77: 1048-57. PMID 11359870 DOI: 10.1046/J.1471-4159.2001.00308.X  0.44
2000 Selley DE, Cao CC, Liu Q, Childers SR. Effects of sodium on agonist efficacy for G-protein activation in μ-opioid receptor-transfected CHO cells and rat thalamus British Journal of Pharmacology. 130: 987-996. PMID 10882382  0.44
2000 Sim-Selley LJ, Selley DE, Vogt LJ, Childers SR, Martin TJ. Chronic heroin self-administration desensitizes mu opioid receptor-activated G-proteins in specific regions of rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4555-62. PMID 10844025  0.44
2000 Maher CE, Selley DE, Childers SR. Relationship of mu opioid receptor binding to activation of G-proteins in specific rat brain regions Biochemical Pharmacology. 59: 1395-1401. PMID 10751548 DOI: 10.1016/S0006-2952(00)00272-0  0.44
2000 Sim-Selley LJ, Vogt LJ, Xiao R, Childers SR, Selley DE. Region-specific changes in 5-HT(1A) receptor-activated G-proteins in rat brain following chronic buspirone. European Journal of Pharmacology. 389: 147-53. PMID 10688978 DOI: 10.1016/S0014-2999(99)00875-4  0.44
1998 Breivogel CS, Selley DE, Childers SR. Cannabinoid receptor agonist efficacy for stimulating [35S]GTPγS binding to rat cerebellar membranes correlates with agonist-induced decreases in GDP affinity Journal of Biological Chemistry. 273: 16865-16873. PMID 9642247 DOI: 10.1074/jbc.273.27.16865  0.44
1998 Sim LJ, Liu Q, Childers SR, Selley DE. Endomorphin-stimulated [35S]GTPγs binding in rat brain: Evidence for partial agonist activity at μ-opioid receptors Journal of Neurochemistry. 70: 1567-1576. PMID 9523574  0.44
1998 Selley DE, Breivogel CS, Childers SR. Opioid inhibition of adenylyl cyclase in membranes from pertussis toxin- related NG108-15 cells Journal of Receptor and Signal Transduction Research. 18: 25-50. PMID 9493566  0.44
1997 Martin TJ, Sim LJ, Selley DE, DeMontis MG, Childers SR. Effects of intracerebroventricular administration of β-funaltrexamine on DAMGO-stimulated [35S]GTP-γ-S binding in rat brain sections Synapse. 27: 177-182. PMID 9329153 DOI: 10.1002/(SICI)1098-2396(199711)27:3<177::AID-SYN3>3.0.CO;2-A  0.44
1997 Sim LJ, Selley DE, Childers SR. Autoradiographic visualization in brain of receptor-G protein coupling using [35S]GTP gamma S binding. Methods in Molecular Biology (Clifton, N.J.). 83: 117-132. PMID 9210141 DOI: 10.1385/0-89603-495-X:117  0.44
1997 Breivogel CS, Selley DE, Childers SR. Acute and chronic effects of opioids on δ and μ receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes Journal of Neurochemistry. 68: 1462-1472. PMID 9084416  0.44
1997 Selley DE, Nestler EJ, Breivogel CS, Childers SR. Opioid receptor-coupled G-proteins in rat locus coeruleus membranes: Decrease in activity after chronic morphine treatment Brain Research. 746: 10-18. PMID 9037478 DOI: 10.1016/S0006-8993(96)01125-0  0.44
1997 Selley DE, Sim LJ, Xiao R, Liu Q, Childers SR. μ-Opioid receptor-stimulated guanosine-5'-O-(γ-thio)-triphosphate binding in rat thalamus and cultured cell lines: Signal transduction mechanisms underlying agonist efficacy Molecular Pharmacology. 51: 87-96. PMID 9016350  0.44
1996 Sim LJ, Selley DE, Xiao R, Childers SR. Differences in G-protein activation by μ- and δ-opioid, and cannabinoid, receptors in rat striatum European Journal of Pharmacology. 307: 97-105. PMID 8831110 DOI: 10.1016/0014-2999(96)00211-7  0.44
1996 Sim LJ, Selley DE, Dworkin SI, Childers SR. Effects of chronic morphine administration on mu opioid receptor-stimulated [35S]GTPgammaS autoradiography in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2684-92. PMID 8786444  0.44
1996 Selley DE, Stark S, Sim LJ, Childers SR. Cannabinoid receptor stimulation of guanosine-5'-O-(3- [35S]thio)triphosphate binding in rat brain membranes Life Sciences. 59: 659-668. PMID 8761016 DOI: 10.1016/0024-3205(96)00347-5  0.44
1995 Sim LJ, Selley DE, Childers SR. In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5′-[γ-[35S]thio]-triphosphate binding Proceedings of the National Academy of Sciences of the United States of America. 92: 7242-7246. PMID 7638174  0.44
1994 Sim LJ, Selley DE, Tsai KP, Morris M. Calcium and cAMP mediated stimulation of Fos in cultured hypothalamic tyrosine hydroxylase-immunoreactive neurons Brain Research. 653: 155-160. PMID 7982047 DOI: 10.1016/0006-8993(94)90384-0  0.44
1994 Sim LJ, Selley DE, Tsai KP, Morris M. D2 inhibition of stimulated Fos immunoreactivity in cultured tyrosine hydroxylase-ir hypothalamic neurons Brain Research. 651: 311-316. PMID 7922580 DOI: 10.1016/0006-8993(94)90711-0  0.44
1994 Selley DE, Breivogel CS, Childers SR. Opioid inhibition of adenylyl cyclase remaining after pertussis toxin treatment of NG108-15 cells: Possible involvement of tightly bound GTP. Regulatory Peptides. 54: 265-266. DOI: 10.1016/0167-0115(94)90491-X  0.44
1994 Selley DE, Childers SR, Chang KJ. BW373U86, a non-peptide δ opioid agonist with novel receptor-protein-mediated actions Regulatory Peptides. 53: S27-S28. DOI: 10.1016/0167-0115(94)90224-0  0.44
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