| Year |
Citation |
Score |
| 2017 |
Allen KM, Coughlan KA, Mahmood FN, Valentine RJ, Ruderman NB, Saha AK. The effects of troglitazone on AMPK in HepG2 cells. Archives of Biochemistry and Biophysics. PMID 28526426 DOI: 10.1016/j.abb.2017.05.010 |
0.425 |
|
| 2016 |
Weikel KA, Cacicedo JM, Ruderman NB, Ido Y. Knockdown of GSK3β Increases Basal Autophagy and AMPK Signaling in Nutrient-laden Human Aortic Endothelial Cells. Bioscience Reports. PMID 27534430 DOI: 10.1042/Bsr20160174 |
0.767 |
|
| 2016 |
Weikel KA, Ruderman NB, Cacicedo JM. Unraveling the actions of AMP-activated protein kinase in metabolic diseases: Systemic to molecular insights. Metabolism: Clinical and Experimental. 65: 634-45. PMID 27085772 DOI: 10.1016/J.Metabol.2016.01.005 |
0.747 |
|
| 2016 |
Pepin É, Al-Mass A, Attané C, Zhang K, Lamontagne J, Lussier R, Madiraju SR, Joly E, Ruderman NB, Sladek R, Prentki M, Peyot ML. Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression. Plos One. 11: e0153017. PMID 27043434 DOI: 10.1371/Journal.Pone.0153017 |
0.366 |
|
| 2016 |
Coughlan KA, Valentine RJ, Sudit BS, Allen K, Dagon Y, Kahn BB, Ruderman NB, Saha AK. PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells. The Journal of Biological Chemistry. PMID 26797128 DOI: 10.1074/Jbc.M115.696849 |
0.443 |
|
| 2015 |
Xu XJ, Apovian C, Hess D, Carmine B, Saha A, Ruderman N. Improved Insulin Sensitivity 3 Months After RYGB Surgery Is Associated With Increased Subcutaneous Adipose Tissue AMPK Activity and Decreased Oxidative Stress. Diabetes. 64: 3155-9. PMID 26001396 DOI: 10.2337/Db14-1765 |
0.422 |
|
| 2015 |
Coughlan KA, Balon TW, Valentine RJ, Petrocelli R, Schultz V, Brandon A, Cooney GJ, Kraegen EW, Ruderman NB, Saha AK. Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats. Plos One. 10: e0127388. PMID 25996822 DOI: 10.1371/journal.pone.0127388 |
0.427 |
|
| 2015 |
Brandon AE, Tid-Ang J, Wright LE, Stuart E, Suryana E, Bentley N, Turner N, Cooney GJ, Ruderman NB, Kraegen EW. Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance. Plos One. 10: e0121959. PMID 25798922 DOI: 10.1371/journal.pone.0121959 |
0.342 |
|
| 2015 |
Ido Y, Duranton A, Lan F, Weikel KA, Breton L, Ruderman NB. Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPK-FOXO3 cascade in cultured primary human keratinocytes. Plos One. 10: e0115341. PMID 25647160 DOI: 10.1371/journal.pone.0115341 |
0.341 |
|
| 2015 |
Weikel KA, Cacicedo JM, Ruderman NB, Ido Y. Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells. American Journal of Physiology. Cell Physiology. 308: C249-63. PMID 25354528 DOI: 10.1152/Ajpcell.00265.2014 |
0.774 |
|
| 2014 |
Valentine RJ, Coughlan KA, Ruderman NB, Saha AK. Insulin inhibits AMPK activity and phosphorylates AMPK Ser⁴⁸⁵/⁴⁹¹ through Akt in hepatocytes, myotubes and incubated rat skeletal muscle. Archives of Biochemistry and Biophysics. 562: 62-9. PMID 25172224 DOI: 10.1016/j.abb.2014.08.013 |
0.427 |
|
| 2014 |
Coughlan KA, Valentine RJ, Ruderman NB, Saha AK. AMPK activation: a therapeutic target for type 2 diabetes? Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy. 7: 241-53. PMID 25018645 DOI: 10.2147/DMSO.S43731 |
0.456 |
|
| 2014 |
Xu XJ, Valentine RJ, Ruderman NB. AMP-activated Protein Kinase (AMPK): Does This Master Regulator of Cellular Energy State Distinguish Insulin Sensitive from Insulin Resistant Obesity? Current Obesity Reports. 3: 248-55. PMID 24891985 DOI: 10.1007/s13679-014-0095-x |
0.334 |
|
| 2014 |
Krasner NM, Ido Y, Ruderman NB, Cacicedo JM. Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism. Plos One. 9: e97554. PMID 24835252 DOI: 10.1371/Journal.Pone.0097554 |
0.72 |
|
| 2013 |
Coughlan KA, Valentine RJ, Ruderman NB, Saha AK. Nutrient Excess in AMPK Downregulation and Insulin Resistance. Journal of Endocrinology, Diabetes & Obesity. 1: 1008. PMID 26120590 |
0.468 |
|
| 2013 |
Ruderman NB, Carling D, Prentki M, Cacicedo JM. AMPK, insulin resistance, and the metabolic syndrome. The Journal of Clinical Investigation. 123: 2764-72. PMID 23863634 DOI: 10.1172/Jci67227 |
0.745 |
|
| 2013 |
Lamontagne J, Jalbert-Arsenault E, Pepin E, Peyot ML, Ruderman NB, Nolan CJ, Joly E, Madiraju SR, Poitout V, Prentki M. Pioglitazone acutely reduces energy metabolism and insulin secretion in rats. Diabetes. 62: 2122-9. PMID 23378607 DOI: 10.2337/Db12-0428 |
0.31 |
|
| 2013 |
Tabit CE, Shenouda SM, Holbrook M, Fetterman JL, Kiani S, Frame AA, Kluge MA, Held A, Dohadwala MM, Gokce N, Farb MG, Rosenzweig J, Ruderman N, Vita JA, Hamburg NM. Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitus. Circulation. 127: 86-95. PMID 23204109 DOI: 10.1161/Circulationaha.112.127514 |
0.432 |
|
| 2012 |
Ido Y, Duranton A, Lan F, Cacicedo JM, Chen TC, Breton L, Ruderman NB. Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes. Plos One. 7: e35092. PMID 22514710 DOI: 10.1371/Journal.Pone.0035092 |
0.727 |
|
| 2012 |
Ix JH, Biggs ML, Mukamal KJ, Kizer JR, Zieman SJ, Siscovick DS, Mozzaffarian D, Jensen MK, Nelson L, Ruderman N, Djousse L. Association of fetuin-a with incident diabetes mellitus in community-living older adults: the cardiovascular health study. Circulation. 125: 2316-22. PMID 22511752 DOI: 10.1161/Circulationaha.111.072751 |
0.315 |
|
| 2012 |
Nelson LE, Valentine RJ, Cacicedo JM, Gauthier MS, Ido Y, Ruderman NB. A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells. American Journal of Physiology. Cell Physiology. 303: C4-C13. PMID 22378745 DOI: 10.1152/Ajpcell.00296.2011 |
0.755 |
|
| 2012 |
Xu XJ, Gauthier MS, Hess DT, Apovian CM, Cacicedo JM, Gokce N, Farb M, Valentine RJ, Ruderman NB. Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue. Journal of Lipid Research. 53: 792-801. PMID 22323564 DOI: 10.1194/Jlr.P022905 |
0.741 |
|
| 2011 |
Saha AK, Xu XJ, Balon TW, Brandon A, Kraegen EW, Ruderman NB. Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation? Cell Cycle (Georgetown, Tex.). 10: 3447-51. PMID 22067655 DOI: 10.4161/cc.10.20.17886 |
0.432 |
|
| 2011 |
Chuang JH, Kao YJ, Ruderman NB, Tung LC, Lin Y. Optimal concentrations of N-decanoyl-N-methylglucamine and sodium dodecyl sulfate allow the extraction and analysis of membrane proteins. Analytical Biochemistry. 418: 298-300. PMID 21871431 DOI: 10.1016/J.Ab.2011.08.006 |
0.49 |
|
| 2011 |
Cacicedo JM, Gauthier MS, Lebrasseur NK, Jasuja R, Ruderman NB, Ido Y. Acute exercise activates AMPK and eNOS in the mouse aorta. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1255-65. PMID 21724864 DOI: 10.1152/Ajpheart.01279.2010 |
0.738 |
|
| 2011 |
Brandon AE, Hoy AJ, Wright LE, Turner N, Hegarty BD, Iseli TJ, Julia Xu X, Cooney GJ, Saha AK, Ruderman NB, Kraegen EW. The evolution of insulin resistance in muscle of the glucose infused rat. Archives of Biochemistry and Biophysics. 509: 133-41. PMID 21420928 DOI: 10.1016/j.abb.2011.03.008 |
0.355 |
|
| 2011 |
Cacicedo JM, Benjachareonwong S, Chou E, Yagihashi N, Ruderman NB, Ido Y. Activation of AMP-activated protein kinase prevents lipotoxicity in retinal pericytes. Investigative Ophthalmology & Visual Science. 52: 3630-9. PMID 21345991 DOI: 10.1167/Iovs.10-5784 |
0.751 |
|
| 2011 |
Gauthier MS, O'Brien EL, Bigornia S, Mott M, Cacicedo JM, Xu XJ, Gokce N, Apovian C, Ruderman N. Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans. Biochemical and Biophysical Research Communications. 404: 382-7. PMID 21130749 DOI: 10.1016/J.Bbrc.2010.11.127 |
0.75 |
|
| 2010 |
Saha AK, Xu XJ, Lawson E, Deoliveira R, Brandon AE, Kraegen EW, Ruderman NB. Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. Diabetes. 59: 2426-34. PMID 20682696 DOI: 10.2337/db09-1870 |
0.435 |
|
| 2010 |
Liu Q, Gauthier MS, Sun L, Ruderman N, Lodish H. Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: Requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio Faseb Journal. 24: 4229-4239. PMID 20667975 DOI: 10.1096/Fj.10-159723 |
0.543 |
|
| 2010 |
Ruderman NB, Xu XJ, Nelson L, Cacicedo JM, Saha AK, Lan F, Ido Y. AMPK and SIRT1: a long-standing partnership? American Journal of Physiology. Endocrinology and Metabolism. 298: E751-60. PMID 20103737 DOI: 10.1152/Ajpendo.00745.2009 |
0.73 |
|
| 2009 |
Joly E, Roduit R, Peyot ML, Habinowski SA, Ruderman NB, Witters LA, Prentki M. Glucose represses PPARα gene expression via AMP-activated protein kinase but not via p38 mitogen-activated protein kinase in the pancreatic β-cell. Journal of Diabetes. 1: 263-72. PMID 20923527 DOI: 10.1111/J.1753-0407.2009.00043.X |
0.37 |
|
| 2009 |
Bendayan M, Londono I, Kemp BE, Hardie GD, Ruderman N, Prentki M. Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 57: 963-71. PMID 19581628 DOI: 10.1369/Jhc.2009.954016 |
0.327 |
|
| 2009 |
Kelly M, Gauthier MS, Saha AK, Ruderman NB. Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization. Diabetes. 58: 1953-60. PMID 19502419 DOI: 10.2337/Db08-1293 |
0.705 |
|
| 2009 |
Lamontagne J, Pepin E, Peyot ML, Joly E, Ruderman NB, Poitout V, Madiraju SR, Nolan CJ, Prentki M. Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations. Endocrinology. 150: 3465-74. PMID 19406947 DOI: 10.1210/En.2008-1557 |
0.341 |
|
| 2009 |
Peyot ML, Guay C, Latour MG, Lamontagne J, Lussier R, Pineda M, Ruderman NB, Haemmerle G, Zechner R, Joly E, Madiraju SR, Poitout V, Prentki M. Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion. The Journal of Biological Chemistry. 284: 16848-59. PMID 19389712 DOI: 10.1074/Jbc.M109.006650 |
0.338 |
|
| 2009 |
Richter EA, Ruderman NB. AMPK and the biochemistry of exercise: implications for human health and disease. The Biochemical Journal. 418: 261-75. PMID 19196246 DOI: 10.1042/BJ20082055 |
0.402 |
|
| 2009 |
Suchankova G, Nelson LE, Gerhart-Hines Z, Kelly M, Gauthier MS, Saha AK, Ido Y, Puigserver P, Ruderman NB. Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells. Biochemical and Biophysical Research Communications. 378: 836-41. PMID 19071085 DOI: 10.1016/J.Bbrc.2008.11.130 |
0.738 |
|
| 2008 |
Lan F, Cacicedo JM, Ruderman N, Ido Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. The Journal of Biological Chemistry. 283: 27628-35. PMID 18687677 DOI: 10.1074/Jbc.M805711200 |
0.771 |
|
| 2008 |
Gauthier MS, Miyoshi H, Souza SC, Cacicedo JM, Saha AK, Greenberg AS, Ruderman NB. AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. The Journal of Biological Chemistry. 283: 16514-24. PMID 18390901 DOI: 10.1074/Jbc.M708177200 |
0.775 |
|
| 2006 |
Ruderman NB, Keller C, Richard AM, Saha AK, Luo Z, Xiang X, Giralt M, Ritov VB, Menshikova EV, Kelley DE, Hidalgo J, Pedersen BK, Kelly M. Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome. Diabetes. 55: S48-54. PMID 17130644 DOI: 10.2337/Db06-S007 |
0.709 |
|
| 2006 |
Ruderman NB, Saha AK. Metabolic syndrome: adenosine monophosphate-activated protein kinase and malonyl coenzyme A. Obesity (Silver Spring, Md.). 14: 25S-33S. PMID 16642960 DOI: 10.1038/oby.2006.279 |
0.35 |
|
| 2006 |
LeBrasseur NK, Kelly M, Tsao TS, Farmer SR, Saha AK, Ruderman NB, Tomas E. Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues. American Journal of Physiology. Endocrinology and Metabolism. 291: E175-81. PMID 16464908 DOI: 10.1152/Ajpendo.00453.2005 |
0.74 |
|
| 2006 |
Kuhl JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB, Andersen KL, Saha AK, et al. Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. American Journal of Physiology. Endocrinology and Metabolism. 290: E1296-303. PMID 16434556 DOI: 10.1152/ajpendo.00341.2005 |
0.336 |
|
| 2006 |
Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, Pang Z, Chen AS, Ruderman NB, Chen H, Rossetti L, Scherer PE. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. The Journal of Biological Chemistry. 281: 2654-60. PMID 16326714 DOI: 10.1074/Jbc.M505311200 |
0.389 |
|
| 2006 |
Kraegen EW, Saha AK, Preston E, Wilks D, Hoy AJ, Cooney GJ, Ruderman NB. Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats. American Journal of Physiology. Endocrinology and Metabolism. 290: E471-9. PMID 16234268 DOI: 10.1152/ajpendo.00316.2005 |
0.394 |
|
| 2005 |
Boden G, She P, Mozzoli M, Cheung P, Gumireddy K, Reddy P, Xiang X, Luo Z, Ruderman N. Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver. Diabetes. 54: 3458-65. PMID 16306362 DOI: 10.2337/Diabetes.54.12.3458 |
0.457 |
|
| 2005 |
Assifi MM, Suchankova G, Constant S, Prentki M, Saha AK, Ruderman NB. AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. American Journal of Physiology. Endocrinology and Metabolism. 289: E794-800. PMID 15956049 DOI: 10.1152/Ajpendo.00144.2005 |
0.352 |
|
| 2005 |
Cacicedo JM, Benjachareowong S, Chou E, Ruderman NB, Ido Y. Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide. Diabetes. 54: 1838-45. PMID 15919807 DOI: 10.2337/Diabetes.54.6.1838 |
0.734 |
|
| 2005 |
Luo Z, Saha AK, Xiang X, Ruderman NB. AMPK, the metabolic syndrome and cancer. Trends in Pharmacological Sciences. 26: 69-76. PMID 15681023 DOI: 10.1016/J.Tips.2004.12.011 |
0.357 |
|
| 2005 |
Suchankova G, Tekle M, Saha AK, Ruderman NB, Clarke SD, Gettys TW. Dietary polyunsaturated fatty acids enhance hepatic AMP-activated protein kinase activity in rats. Biochemical and Biophysical Research Communications. 326: 851-8. PMID 15607747 DOI: 10.1016/J.Bbrc.2004.11.114 |
0.334 |
|
| 2005 |
Ye J, Ruderman NB, Kraegen EW. AMP-activated protein kinase and malonyl-CoA: Targets for treating insulin resistance? Drug Discovery Today: Therapeutic Strategies. 2: 157-163. DOI: 10.1016/J.DDSTR.2005.05.019 |
0.368 |
|
| 2004 |
Yu X, McCorkle S, Wang M, Lee Y, Li J, Saha AK, Unger RH, Ruderman NB. Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. Diabetologia. 47: 2012-21. PMID 15578153 DOI: 10.1007/S00125-004-1570-9 |
0.361 |
|
| 2004 |
Cacicedo JM, Yagihashi N, Keaney JF, Ruderman NB, Ido Y. AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells. Biochemical and Biophysical Research Communications. 324: 1204-9. PMID 15504342 DOI: 10.1016/J.Bbrc.2004.09.177 |
0.748 |
|
| 2004 |
Zang M, Zuccollo A, Hou X, Nagata D, Walsh K, Herscovitz H, Brecher P, Ruderman NB, Cohen RA. AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. The Journal of Biological Chemistry. 279: 47898-905. PMID 15371448 DOI: 10.1074/Jbc.M408149200 |
0.448 |
|
| 2004 |
Tomas E, Kelly M, Xiang X, Tsao TS, Keller C, Keller P, Luo Z, Lodish H, Saha AK, Unger R, Ruderman NB. Metabolic and hormonal interactions between muscle and adipose tissue. The Proceedings of the Nutrition Society. 63: 381-5. PMID 15294059 DOI: 10.1079/PNS2004356 |
0.692 |
|
| 2004 |
Kelly M, Keller C, Avilucea PR, Keller P, Luo Z, Xiang X, Giralt M, Hidalgo J, Saha AK, Pedersen BK, Ruderman NB. AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise. Biochemical and Biophysical Research Communications. 320: 449-54. PMID 15219849 DOI: 10.1016/J.Bbrc.2004.05.188 |
0.665 |
|
| 2004 |
Ruderman N, Prentki M. AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nature Reviews. Drug Discovery. 3: 340-51. PMID 15060529 DOI: 10.1038/Nrd1344 |
0.471 |
|
| 2004 |
Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes. 53: 1007-19. PMID 15047616 DOI: 10.2337/Diabetes.53.4.1007 |
0.458 |
|
| 2004 |
Saha AK, Avilucea PR, Ye JM, Assifi MM, Kraegen EW, Ruderman NB. Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo. Biochemical and Biophysical Research Communications. 314: 580-5. PMID 14733947 |
0.316 |
|
| 2003 |
Saha AK, Ruderman NB. Malonyl-CoA and AMP-activated protein kinase: an expanding partnership. Molecular and Cellular Biochemistry. 253: 65-70. PMID 14619957 |
0.449 |
|
| 2003 |
Tsao TS, Tomas E, Murrey HE, Hug C, Lee DH, Ruderman NB, Heuser JE, Lodish HF. Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways. The Journal of Biological Chemistry. 278: 50810-7. PMID 14522956 DOI: 10.1074/Jbc.M309469200 |
0.311 |
|
| 2003 |
Ruderman NB, Saha AK, Kraegen EW. Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity. Endocrinology. 144: 5166-71. PMID 14500570 DOI: 10.1210/en.2003-0849 |
0.394 |
|
| 2003 |
Ruderman NB, Park H, Kaushik VK, Dean D, Constant S, Prentki M, Saha AK. AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise Acta Physiologica Scandinavica. 178: 435-442. PMID 12864749 DOI: 10.1046/J.1365-201X.2003.01164.X |
0.43 |
|
| 2003 |
Itani SI, Saha AK, Kurowski TG, Coffin HR, Tornheim K, Ruderman NB. Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase. Diabetes. 52: 1635-40. PMID 12829626 DOI: 10.2337/Diabetes.52.7.1635 |
0.369 |
|
| 2003 |
Ruderman NB, Cacicedo JM, Itani S, Yagihashi N, Saha AK, Ye JM, Chen K, Zou M, Carling D, Boden G, Cohen RA, Keaney J, Kraegen EW, Ido Y. Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. Biochemical Society Transactions. 31: 202-6. PMID 12546685 DOI: 10.1042/Bst0310202 |
0.791 |
|
| 2003 |
Båvenholm PN, Kuhl J, Pigon J, Saha AK, Ruderman NB, Efendic S. Insulin resistance in type 2 diabetes: association with truncal obesity, impaired fitness, and atypical malonyl coenzyme A regulation. The Journal of Clinical Endocrinology and Metabolism. 88: 82-7. PMID 12519834 DOI: 10.1210/jc.2002-020330 |
0.301 |
|
| 2003 |
Zinman B, Ruderman N, Campaigne BN, Devlin JT, Schneider SH. Physical activity/exercise and diabetes mellitus. Diabetes Care. 26: S73-7. PMID 12502622 DOI: 10.2337/Diacare.26.2007.S73 |
0.316 |
|
| 2002 |
Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc, Itani SI, Lodish HF, Ruderman NB. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation Proceedings of the National Academy of Sciences of the United States of America. 99: 16309-16313. PMID 12456889 DOI: 10.1073/Pnas.222657499 |
0.445 |
|
| 2002 |
Iglesias MA, Ye JM, Frangioudakis G, Saha AK, Tomas E, Ruderman NB, Cooney GJ, Kraegen EW. AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats. Diabetes. 51: 2886-94. PMID 12351423 |
0.372 |
|
| 2002 |
Tomás E, Zorzano A, Ruderman NB. Exercise and insulin signaling: a historical perspective. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 765-72. PMID 12133890 DOI: 10.1152/japplphysiol.00267.2002 |
0.323 |
|
| 2002 |
Shafrir E, Ziv E, Saha AK, Ruderman NB. Regulation of muscle malonyl-CoA levels in the nutritionally insulin-resistant desert gerbil, Psammomys obesus. Diabetes/Metabolism Research and Reviews. 18: 217-23. PMID 12112940 DOI: 10.1002/dmrr.288 |
0.343 |
|
| 2002 |
Lin Y, Brady MJ, Wolanske K, Holbert R, Ruderman NB, Yaney GC. Alterations of nPKC distribution, but normal Akt/PKB activation in denervated rat soleus muscle. American Journal of Physiology. Endocrinology and Metabolism. 283: E318-25. PMID 12110537 DOI: 10.1152/Ajpendo.00390.2001 |
0.675 |
|
| 2002 |
Itani SI, Ruderman NB, Schmieder F, Boden G. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes. 51: 2005-11. PMID 12086926 DOI: 10.2337/Diabetes.51.7.2005 |
0.381 |
|
| 2002 |
Tomás E, Lin YS, Dagher Z, Saha A, Luo Z, Ido Y, Ruderman NB. Hyperglycemia and insulin resistance: possible mechanisms. Annals of the New York Academy of Sciences. 967: 43-51. PMID 12079834 DOI: 10.1111/J.1749-6632.2002.Tb04262.X |
0.796 |
|
| 2002 |
Park H, Kaushik VK, Constant S, Prentki M, Przybytkowski E, Ruderman NB, Saha AK. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. The Journal of Biological Chemistry. 277: 32571-7. PMID 12065578 DOI: 10.1074/Jbc.M201692200 |
0.377 |
|
| 2002 |
Eckel RH, Wassef M, Chait A, Sobel B, Barrett E, King G, Lopes-Virella M, Reusch J, Ruderman N, Steiner G, Vlassara H. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes Circulation. 105: e138-143. PMID 11994264 DOI: 10.1161/01.Cir.0000013954.65303.C5 |
0.394 |
|
| 2002 |
Xiang X, Yuan M, Song Y, Ruderman N, Wen R, Luo Z. 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1. Molecular Endocrinology (Baltimore, Md.). 16: 552-62. PMID 11875115 DOI: 10.1210/Mend.16.3.0790 |
0.425 |
|
| 2002 |
Ido Y, Carling D, Ruderman N. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. Diabetes. 51: 159-67. PMID 11756336 DOI: 10.2337/Diabetes.51.1.159 |
0.551 |
|
| 2002 |
Sternthal E, Ruderman N. Insulin: Promise and problems at 80 years Current Opinion in Endocrinology & Diabetes. 9: 283-284. DOI: 10.1097/00060793-200208000-00001 |
0.32 |
|
| 2001 |
Patel N, Khayat ZA, Ruderman NB, Klip A. Dissociation of 5' AMP-activated protein kinase activation and glucose uptake stimulation by mitochondrial uncoupling and hyperosmolar stress: differential sensitivities to intracellular Ca2+ and protein kinase C inhibition. Biochemical and Biophysical Research Communications. 285: 1066-70. PMID 11467861 DOI: 10.1006/Bbrc.2001.5275 |
0.378 |
|
| 2001 |
Kaushik VK, Young ME, Dean DJ, Kurowski TG, Saha AK, Ruderman NB. Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR. American Journal of Physiology. Endocrinology and Metabolism. 281: E335-40. PMID 11440910 DOI: 10.1152/AJPENDO.2001.281.2.E335 |
0.35 |
|
| 2001 |
Dagher Z, Ruderman N, Tornheim K, Ido Y. Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells. Circulation Research. 88: 1276-82. PMID 11420304 DOI: 10.1161/Hh1201.092998 |
0.746 |
|
| 2001 |
Lin Y, Itani SI, Kurowski TG, Dean DJ, Luo Z, Yaney GC, Ruderman NB. Inhibition of insulin signaling and glycogen synthesis by phorbol dibutyrate in rat skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 281: E8-E15. PMID 11404218 DOI: 10.1152/Ajpendo.2001.281.1.E8 |
0.663 |
|
| 2001 |
Ruderman N, Flier JS. Cell biology. Chewing the fat--ACC and energy balance. Science (New York, N.Y.). 291: 2558-9. PMID 11286278 DOI: 10.1126/Science.1060277 |
0.304 |
|
| 2000 |
Dean D, Daugaard JR, Young ME, Saha A, Vavvas D, Asp S, Kiens B, Kim KH, Witters L, Richter EA, Ruderman N. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. Diabetes. 49: 1295-300. PMID 10923628 DOI: 10.2337/Diabetes.49.8.1295 |
0.392 |
|
| 2000 |
Saha AK, Schwarsin AJ, Roduit R, Masse F, Kaushik V, Tornheim K, Prentki M, Ruderman NB. Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Journal of Biological Chemistry. 275: 24279-24283. PMID 10854420 DOI: 10.1074/Jbc.C000291200 |
0.371 |
|
| 2000 |
Laybutt DR, Schmitz-Peiffer C, Saha AK, Ruderman NB, Biden TJ, Kraegen EW. Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat. The American Journal of Physiology. 277: E1070-6. PMID 10600797 DOI: 10.1152/ajpendo.1999.277.6.E1070 |
0.386 |
|
| 1999 |
Ruderman NB, Saha AK, Vavvas D, Witters LA. Malonyl-CoA, fuel sensing, and insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 276: E1-E18. PMID 29590890 DOI: 10.1152/ajpendo.1999.276.1.E1 |
0.481 |
|
| 1999 |
Dagher Z, Ruderman N, Tornheim K, Ido Y. The effect of AMP-activated protein kinase and its activator AICAR on the metabolism of human umbilical vein endothelial cells. Biochemical and Biophysical Research Communications. 265: 112-5. PMID 10548499 DOI: 10.1006/Bbrc.1999.1635 |
0.787 |
|
| 1999 |
Saha AK, Laybutt DR, Dean D, Vavvas D, Sebokova E, Ellis B, Klimes I, Kraegen EW, Shafrir E, Ruderman NB. Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. The American Journal of Physiology. 276: E1030-7. PMID 10362615 DOI: 10.1152/ajpendo.1999.276.6.E1030 |
0.316 |
|
| 1999 |
Ruderman NB, Dean D. Malonyl CoA, long chain fatty acyl CoA and insulin resistance in skeletal muscle. Journal of Basic and Clinical Physiology and Pharmacology. 9: 295-308. PMID 10212840 DOI: 10.1515/JBCPP.1998.9.2-4.295 |
0.404 |
|
| 1999 |
Goalstone ML, Wall K, Leitner JW, Kurowski T, Ruderman N, Pan SJ, Ivy JL, Moller DE, Draznin B. Increased amounts of farnesylated p21Ras in tissues of hyperinsulinaemic animals. Diabetologia. 42: 310-6. PMID 10096783 DOI: 10.1007/S001250051156 |
0.447 |
|
| 1999 |
Kurowski TG, Lin Y, Luo Z, Tsichlis PN, Buse MG, Heydrick SJ, Ruderman NB. Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle. Diabetes. 48: 658-63. PMID 10078574 DOI: 10.2337/Diabetes.48.3.658 |
0.652 |
|
| 1998 |
Ruderman NB, Saha AK, Vavvas D, Kurowski T, Laybutt DR, Schmitz-Peiffer C, Biden T, Kraegen EW. Malonyl CoA as a metabolic switch and a regulator of insulin sensitivity. Advances in Experimental Medicine and Biology. 441: 263-70. PMID 9781332 DOI: 10.1007/978-1-4899-1928-1_24 |
0.394 |
|
| 1998 |
Ruderman N, Chisholm D, Pi-Sunyer X, Schneider S. The metabolically obese, normal-weight individual revisited. Diabetes. 47: 699-713. PMID 9588440 DOI: 10.2337/Diabetes.47.5.699 |
0.359 |
|
| 1998 |
Khan F, Cohen RA, Ruderman NB, Chipkin SR, Coffman JD. Vasodilator responses in the forearm skin of patients with insulin-dependent diabetes mellitus. Vascular Medicine (London, England). 1: 187-93. PMID 9546937 DOI: 10.1177/1358863X9600100303 |
0.308 |
|
| 1997 |
Oakes ND, Bell KS, Furler SM, Camilleri S, Saha AK, Ruderman NB, Chisholm DJ, Kraegen EW. Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. Diabetes. 46: 2022-8. PMID 9392490 DOI: 10.2337/DIAB.46.12.2022 |
0.334 |
|
| 1997 |
Vavvas D, Apazidis A, Saha AK, Gamble J, Patel A, Kemp BE, Witters LA, Ruderman NB. Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle. The Journal of Biological Chemistry. 272: 13255-61. PMID 9148944 DOI: 10.1074/jbc.272.20.13255 |
0.314 |
|
| 1997 |
Saha AK, Vavvas D, Kurowski TG, Apazidis A, Witters LA, Shafrir E, Ruderman NB. Malonyl-CoA regulation in skeletal muscle: its link to cell citrate and the glucose-fatty acid cycle. The American Journal of Physiology. 272: E641-8. PMID 9142886 DOI: 10.1152/ajpendo.1997.272.4.E641 |
0.364 |
|
| 1996 |
Gupta S, Phipps K, Ruderman NB. Differential stimulation of Na+ pump activity by insulin and nitric oxide in rabbit aorta. The American Journal of Physiology. 270: H1287-93. PMID 8967368 DOI: 10.1152/ajpheart.1996.270.4.H1287 |
0.366 |
|
| 1995 |
Saha AK, Kurowski TG, Ruderman NB. A malonyl-CoA fuel-sensing mechanism in muscle: effects of insulin, glucose, and denervation. The American Journal of Physiology. 269: E283-9. PMID 7653546 DOI: 10.1152/ajpendo.1995.269.2.E283 |
0.321 |
|
| 1994 |
Chen KS, Heydrick SJ, Brown ML, Friel JC, Ruderman NB. Insulin increases a biochemically distinct pool of diacylglycerol in the rat soleus muscle. The American Journal of Physiology. 266: E479-85. PMID 8166270 DOI: 10.1152/ajpendo.1994.266.3.E479 |
0.319 |
|
| 1993 |
Chen KS, Friel JC, Ruderman NB. Regulation of phosphatidylinositol 3-kinase by insulin in rat skeletal muscle. The American Journal of Physiology. 265: E736-42. PMID 8238500 DOI: 10.1152/ajpendo.1993.265.5.E736 |
0.368 |
|
| 1992 |
Balon TW, Treadway JL, Hughes JB, Young JC, Ruderman NB. Effect of prior exercise and insulin on potential thermogenic systems in rat skeletal muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 72: 2203-9. PMID 1629074 DOI: 10.1152/Jappl.1992.72.6.2203 |
0.32 |
|
| 1992 |
Coderre L, Monfar MM, Chen KS, Heydrick SJ, Kurowski TG, Ruderman NB, Pilch PF. Alteration in the expression of GLUT-1 and GLUT-4 protein and messenger RNA levels in denervated rat muscles Endocrinology. 131: 1821-1825. PMID 1396328 DOI: 10.1210/Endo.131.4.1396328 |
0.305 |
|
| 1991 |
Heydrick SJ, Ruderman NB, Kurowski TG, Adams HB, Chen KS. Enhanced stimulation of diacylglycerol and lipid synthesis by insulin in denervated muscle. Altered protein kinase C activity and possible link to insulin resistance. Diabetes. 40: 1707-11. PMID 1756911 DOI: 10.2337/diab.40.12.1707 |
0.397 |
|
| 1991 |
Kapeller R, Chen KS, Yoakim M, Schaffhausen BS, Backer J, White MF, Cantley LC, Ruderman NB. Mutations in the juxtamembrane region of the insulin receptor impair activation of phosphatidylinositol 3-kinase by insulin. Molecular Endocrinology (Baltimore, Md.). 5: 769-77. PMID 1656240 DOI: 10.1210/Mend-5-6-769 |
0.353 |
|
| 1990 |
Balon TW, Zorzano A, Treadway JL, Goodman MN, Ruderman NB. Effect of insulin on protein synthesis and degradation in skeletal muscle after exercise. The American Journal of Physiology. 258: E92-7. PMID 2405703 DOI: 10.1152/Ajpendo.1990.258.1.E92 |
0.314 |
|
| 1990 |
Ruderman N, Apelian AZ, Schneider SH. Exercise in therapy and prevention of type II diabetes. Implications for blacks. Diabetes Care. 13: 1163-8. PMID 2261837 DOI: 10.2337/Diacare.13.11.1163 |
0.326 |
|
| 1990 |
Ruderman NB, Kapeller R, White MF, Cantley LC. Activation of phosphatidylinositol 3-kinase by insulin Proceedings of the National Academy of Sciences of the United States of America. 87: 1411-1415. PMID 2154747 DOI: 10.1073/Pnas.87.4.1411 |
0.372 |
|
| 1989 |
Treadway JL, James DE, Burcel E, Ruderman NB. Effect of exercise on insulin receptor binding and kinase activity in skeletal muscle. The American Journal of Physiology. 256: E138-44. PMID 2643337 DOI: 10.1152/ajpendo.1989.256.1.E138 |
0.344 |
|
| 1987 |
Zorzano A, Balon TW, Jakubowski JA, Goodman MN, Deykin D, Ruderman NB. Effects of insulin and prior exercise on prostaglandin release from perfused rat muscle. Evidence that prostaglandins do not mediate changes in glucose uptake. The Biochemical Journal. 240: 437-43. PMID 3545188 DOI: 10.1042/bj2400437 |
0.307 |
|
| 1987 |
Zorzano A, Balon TW, Goodman MN, Ruderman NB. Glycogen depletion and increased insulin sensitivity and responsiveness in muscle after exercise. The American Journal of Physiology. 251: E664-9. PMID 3538900 DOI: 10.1152/ajpendo.1986.251.6.E664 |
0.326 |
|
| 1986 |
Zorzano A, Balon TW, Goodman MN, Ruderman NB. Additive effects of prior exercise and insulin on glucose and AIB uptake by rat muscle. The American Journal of Physiology. 251: E21-6. PMID 3524258 DOI: 10.1152/ajpendo.1986.251.1.E21 |
0.317 |
|
| 1986 |
Schneider SH, Vitug A, Ruderman N. Atherosclerosis and physical activity. Diabetes/Metabolism Reviews. 1: 513-53. PMID 3522141 DOI: 10.1002/Dmr.5610010410 |
0.325 |
|
| 1985 |
Zorzano A, Balon TW, Garetto LP, Goodman MN, Ruderman NB. Muscle alpha-aminoisobutyric acid transport after exercise: enhanced stimulation by insulin. The American Journal of Physiology. 248: E546-52. PMID 3887941 DOI: 10.1152/ajpendo.1985.248.5.E546 |
0.324 |
|
| 1985 |
Salzman R, Manson JE, Griffing GT, Kimmerle R, Ruderman N, McCall A, Stoltz EI, Mullin C, Small D, Armstrong J. Intranasal aerosolized insulin. Mixed-meal studies and long-term use in type I diabetes. The New England Journal of Medicine. 312: 1078-84. PMID 3885035 DOI: 10.1056/Nejm198504253121702 |
0.395 |
|
| 1984 |
Richter EA, Garetto LP, Goodman MN, Ruderman NB. Enhanced muscle glucose metabolism after exercise: modulation by local factors. The American Journal of Physiology. 246: E476-82. PMID 6430094 DOI: 10.1152/ajpendo.1984.246.6.E476 |
0.332 |
|
| 1984 |
Garetto LP, Richter EA, Goodman MN, Ruderman NB. Enhanced muscle glucose metabolism after exercise in the rat: the two phases. The American Journal of Physiology. 246: E471-5. PMID 6377909 DOI: 10.1152/ajpendo.1984.246.6.E471 |
0.317 |
|
| 1982 |
Richter EA, Garetto LP, Goodman MN, Ruderman NB. Muscle glucose metabolism following exercise in the rat: increased sensitivity to insulin. The Journal of Clinical Investigation. 69: 785-93. PMID 6804492 DOI: 10.1172/JCI110517 |
0.323 |
|
| 1981 |
Conover CA, Rozovski SJ, Ruderman NB. Regulation of ornithine decarboxylase in skeletal muscle: evidence for the involvement of an insulin-dependent serum factor. Diabetes. 30: 678-84. PMID 7018971 DOI: 10.2337/diab.30.8.678 |
0.328 |
|
| 1981 |
Brady LJ, Goodman MN, Kalish FN, Ruderman NB. Insulin binding and sensitivity in rat skeletal muscle: effect of starvation. The American Journal of Physiology. 240: E184-90. PMID 7008629 DOI: 10.1152/ajpendo.1981.240.2.E184 |
0.307 |
|
| 1980 |
Conover CA, Rozovski SJ, Belur ER, Aoki TT, Ruderman NB. Ornithine decarboxylase activity in insulin-deficient states. The Biochemical Journal. 192: 725-32. PMID 7016116 DOI: 10.1042/bj1920725 |
0.307 |
|
| 1979 |
Goodman MN, Ruderman NB. Insulin sensitivity of rat skeletal muscle: effects of starvation and aging. The American Journal of Physiology. 236: E519-23. PMID 443372 DOI: 10.1152/ajpendo.1979.236.5.E519 |
0.311 |
|
| 1976 |
MacDonald M, Neufeldt N, Park BN, Berger M, Ruderman N. Alanine metabolism and gluconeogenesis in the rat. The American Journal of Physiology. 231: 619-26. PMID 961915 DOI: 10.1152/Ajplegacy.1976.231.2.619 |
0.331 |
|
| 1976 |
Berger M, Hagg SA, Goodman MN, Ruderman NB. Glucose metabolism in perfused skeletal muscle. Effects of starvation, diabetes, fatty acids, acetoacetate, insulin and exercise on glucose uptake and disposition. The Biochemical Journal. 158: 191-202. PMID 136249 DOI: 10.1042/bj1580191 |
0.345 |
|
| 1975 |
Shafrir E, Ruderman NB. Enzymes of carbohydrate and fat metabolism in anti-insulin serum diabetes; inactivation by free fatty acids and the protective effect of cellular protein. Diabetologia. 10: 731-42. PMID 4155389 DOI: 10.1007/BF01219535 |
0.301 |
|
| 1975 |
Berger M, Hagg S, Ruderman NB. Glucose metabolism in perfused skeletal muscle. Interaction of insulin and exercise on glucose uptake. The Biochemical Journal. 146: 231-8. PMID 807202 DOI: 10.1042/bj1460231 |
0.332 |
|
| 1974 |
Ruderman NB, Goodman MN. Inhibition of muscle acetoacetate utilization during diabetic ketoacidosis. The American Journal of Physiology. 226: 136-43. PMID 4203779 DOI: 10.1152/Ajplegacy.1974.226.1.136 |
0.313 |
|
| 1973 |
Ruderman NB, Goodman MN. Regulation of ketone body metabolism in skeletal muscle. The American Journal of Physiology. 224: 1391-7. PMID 4712152 DOI: 10.1152/Ajplegacy.1973.224.6.1391 |
0.311 |
|
| 1968 |
Ruderman NB, Herrera MG. Glucose regulation of hepatic gluconeogenesis. The American Journal of Physiology. 214: 1346-51. PMID 5649490 DOI: 10.1152/Ajplegacy.1968.214.6.1346 |
0.324 |
|
| 1968 |
Herrera MG, Kamm D, Ruderman N. Non-hormonal factors in the control of gluconeogenesis. Advances in Enzyme Regulation. 4: 225-35. PMID 4862942 DOI: 10.1016/0065-2571(66)90017-3 |
0.369 |
|
| 1967 |
Ruderman NB, Lauris V, Herrera MG. Insulin preservation of glucokinase activity in isolated perfused rat liver. The American Journal of Physiology. 212: 1169-73. PMID 4290362 DOI: 10.1152/Ajplegacy.1967.212.5.1169 |
0.381 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2015 |
Nolan CJ, Ruderman NB, Kahn SE, Pedersen O, Prentki M. Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes. Diabetes. 64: 673-86. PMID 25713189 DOI: 10.2337/Db14-0694 |
0.299 |
|
| 1977 |
Maizels EZ, Ruderman NB, Goodman MN, Lau D. Effect of acetoacetate on glucose metabolism in the soleus and extensor digitorum longus muscles of the rat. The Biochemical Journal. 162: 557-68. PMID 869905 DOI: 10.1042/bj1620557 |
0.299 |
|
| 1988 |
Sussman I, Carson MP, Schultz V, Wu XP, McCall AL, Ruderman NB, Tornheim K. Chronic exposure to high glucose decreases myo-inositol in cultured cerebral microvascular pericytes but not in endothelium Diabetologia. 31: 771-775. PMID 3240840 DOI: 10.1007/BF00274782 |
0.298 |
|
| 2000 |
Båvenholm PN, Pigon J, Saha AK, Ruderman NB, Efendic S. Fatty acid oxidation and the regulation of malonyl-CoA in human muscle. Diabetes. 49: 1078-83. PMID 10909961 DOI: 10.2337/DIABETES.49.7.1078 |
0.295 |
|
| 1994 |
Saha AK, Kurowski TG, Colca JR, Ruderman NB. Lipid abnormalities in tissues of the KKAy mouse: effects of pioglitazone on malonyl-CoA and diacylglycerol. The American Journal of Physiology. 267: E95-101. PMID 8048519 DOI: 10.1152/ajpendo.1994.267.1.E95 |
0.295 |
|
| 1985 |
Balon TW, Zorzano A, Goodman MN, Ruderman NB. Insulin increases thermogenesis in rat skeletal muscle following exercise. The American Journal of Physiology. 248: E148-51. PMID 3881047 DOI: 10.1152/ajpendo.1985.248.1.E148 |
0.294 |
|
| 1983 |
Goodman MN, Dluz SM, McElaney MA, Belur E, Ruderman NB. Glucose uptake and insulin sensitivity in rat muscle: changes during 3-96 weeks of age. The American Journal of Physiology. 244: E93-100. PMID 6336911 DOI: 10.1152/ajpendo.1983.244.1.E93 |
0.294 |
|
| 2007 |
Hamburg NM, McMackin CJ, Huang AL, Shenouda SM, Widlansky ME, Schulz E, Gokce N, Ruderman NB, Keaney JF, Vita JA. Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2650-6. PMID 17932315 DOI: 10.1161/Atvbaha.107.153288 |
0.294 |
|
| 2005 |
Miller TA, LeBrasseur NK, Cote GM, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB, Sawyer DB. Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes. Biochemical and Biophysical Research Communications. 336: 309-15. PMID 16126172 DOI: 10.1016/J.Bbrc.2005.08.088 |
0.293 |
|
| 2005 |
Ball LE, Berkaw MN, McHenry B, Kraegen EW, Preston E, Wilks D, Cooney GH, Saha A, Ruderman NB, Buse MG. 384 INCREASED GLOBAL POSTTRANSLATIONAL O-GLCNAC MODIFICATION OF LIVER PROTEINS PRECEDES THE DEVELOPMENT OF GLUCOSE-INDUCED INSULIN RESISTANCE IN VIVO Journal of Investigative Medicine. 53: S321.5-S321. DOI: 10.2310/6650.2005.00006.383 |
0.293 |
|
| 1993 |
Ruderman NB, Schneider SH. Diabetes, exercise, and atherosclerosis. Diabetes Care. 15: 1787-93. PMID 1468316 DOI: 10.2337/diacare.15.11.1787 |
0.29 |
|
| 2013 |
Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, ... ... Ruderman NB, et al. SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Molecular Cell. 50: 686-98. PMID 23746352 DOI: 10.1016/J.Molcel.2013.05.012 |
0.285 |
|
| 1984 |
Waldorf AR, Ruderman N, Diamond RD. Specific susceptibility to mucormycosis in murine diabetes and bronchoalveolar macrophage defense against Rhizopus. The Journal of Clinical Investigation. 74: 150-60. PMID 6736246 DOI: 10.1172/Jci111395 |
0.283 |
|
| 2000 |
Chien D, Dean D, Saha AK, Flatt JP, Ruderman NB. Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo. American Journal of Physiology. Endocrinology and Metabolism. 279: E259-65. PMID 10913024 DOI: 10.1152/AJPENDO.2000.279.2.E259 |
0.28 |
|
| 1988 |
Zorzano A, James DE, Ruderman NB, Pilch PF. Insulin-like growth factor I binding and receptor kinase in red and white muscle Febs Letters. 234: 257-262. PMID 2968920 DOI: 10.1016/0014-5793(88)80093-0 |
0.278 |
|
| 1975 |
Goodman MN, Berger M, Ruderman NB. Glucose metabolism in rat skeletal muscle at rest. Effect of starvation, diabetes, ketone bodies and free fatty acids. Diabetes. 23: 881-8. PMID 4279193 DOI: 10.2337/diab.23.11.881 |
0.274 |
|
| 1970 |
Ruderman NB, Toews CJ, Lowy C, Vreeland I, Shafrir E. Inhibition of hepatic gluconeogenesis and fatty acid oxidation by pent-4-enoic acid. The American Journal of Physiology. 219: 51-7. PMID 5424858 DOI: 10.1152/Ajplegacy.1970.219.1.51 |
0.274 |
|
| 2005 |
Roepstorff C, Halberg N, Hillig T, Saha AK, Ruderman NB, Wojtaszewski JF, Richter EA, Kiens B. Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. American Journal of Physiology. Endocrinology and Metabolism. 288: E133-42. PMID 15383373 DOI: 10.1152/ajpendo.00379.2004 |
0.273 |
|
| 1993 |
Ruderman N, Horton E, Kemmer F, Berger M. The lost symposium. Diabetes and exercise 1990. Diabetes Care. 16: 959-60. PMID 8325223 DOI: 10.2337/Diacare.16.6.959 |
0.272 |
|
| 1986 |
Balon TW, Zorzano A, Goodman MN, Ruderman NB. Insulin-enhanced thermogenesis in skeletal muscle after exercise: regulatory factors. The American Journal of Physiology. 251: E294-8. PMID 2875652 DOI: 10.1152/ajpendo.1986.251.3.E294 |
0.272 |
|
| 2004 |
Xiang X, Saha AK, Wen R, Ruderman NB, Luo Z. AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. Biochemical and Biophysical Research Communications. 321: 161-7. PMID 15358229 DOI: 10.1016/J.Bbrc.2004.06.133 |
0.272 |
|
| 1997 |
Ruderman NB, Saha AK, Vavvas D, Heydrick SJ, Kurowski TG. Lipid abnormalities in muscle of insulin-resistant rodents. The malonyl CoA hypothesis. Annals of the New York Academy of Sciences. 827: 221-30. PMID 9329757 DOI: 10.1111/J.1749-6632.1997.TB51837.X |
0.27 |
|
| 1986 |
Lowell BB, Ruderman NB, Goodman MN. Evidence that lysosomes are not involved in the degradation of myofibrillar proteins in rat skeletal muscle. The Biochemical Journal. 234: 237-40. PMID 3707546 DOI: 10.1042/bj2340237 |
0.269 |
|
| 1991 |
Young JC, Kurowski TG, Maurice AM, Nesher R, Ruderman NB. Polymyxin B inhibits contraction-stimulated glucose uptake in rat skeletal muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 70: 1650-4. PMID 2055846 DOI: 10.1152/jappl.1991.70.4.1650 |
0.268 |
|
| 2014 |
Gauthier MS, Pérusse JR, Lavoie MÈ, Sladek R, Madiraju SR, Ruderman NB, Coulombe B, Prentki M, Rabasa-Lhoret R. Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals. The Journal of Clinical Endocrinology and Metabolism. 99: E2518-28. PMID 25210878 DOI: 10.1210/Jc.2014-1662 |
0.268 |
|
| 1983 |
Conover C, Rozovski SJ, Ruderman NB. Partial characterization of an insulin-dependent serum factor that regulates ornithine decarboxylase in skeletal muscle. Diabetes. 31: 500-5. PMID 6759267 DOI: 10.2337/diab.31.6.500 |
0.267 |
|
| 1969 |
Ruderman N, Shafrir E, Bressler R. Relation of fatty acid oxidation tgluconeogenesis: effect of pentenoic acid. Life Sciences. 7: 1083-9. PMID 4305726 DOI: 10.1016/0024-3205(68)90145-8 |
0.263 |
|
| 1986 |
Ruderman NB, Balon T, Zorzano A, Goodman M. The postexercise state: altered effects of insulin on skeletal muscle and their physiologic relevance. Diabetes/Metabolism Reviews. 1: 425-44. PMID 3087715 DOI: 10.1002/dmr.5610010406 |
0.263 |
|
| 1988 |
McCall AL, Sussman I, Tornheim K, Cordero R, Ruderman NB. Effects of hypoglycemia and diabetes on fuel metabolism by rat brain microvessels. The American Journal of Physiology. 254: E272-8. PMID 2964787 DOI: 10.1152/ajpendo.1988.254.3.E272 |
0.262 |
|
| 1992 |
Kimmerle R, Griffing G, McCall A, Ruderman NB, Stoltz E, Melby JC. Could intranasal insulin be useful in the treatment of non-insulin-dependent diabetes mellitus? Diabetes Research and Clinical Practice. 13: 69-75. PMID 1773716 DOI: 10.1016/0168-8227(91)90035-C |
0.261 |
|
| 1981 |
Richter EA, Ruderman NB, Schneider SH. Diabetes and exercise. The American Journal of Medicine. 70: 201-9. PMID 7006392 DOI: 10.1016/0002-9343(81)90427-7 |
0.258 |
|
| 1984 |
McCall AL, Gould JB, Ruderman NB. Diabetes-induced alterations of glucose metabolism in rat cerebral microvessels. The American Journal of Physiology. 247: E462-7. PMID 6496667 DOI: 10.1152/ajpendo.1984.247.4.E462 |
0.256 |
|
| 2006 |
Saha AK, Persons K, Safer JD, Luo Z, Holick MF, Ruderman NB. AMPK regulation of the growth of cultured human keratinocytes. Biochemical and Biophysical Research Communications. 349: 519-24. PMID 16949049 DOI: 10.1016/J.Bbrc.2006.08.107 |
0.255 |
|
| 2010 |
Gauthier MS, Ruderman NB. Adipose tissue inflammation and insulin resistance: all obese humans are not created equal. The Biochemical Journal. 430: e1-4. PMID 20704568 DOI: 10.1042/BJ20101062 |
0.255 |
|
| 2009 |
Wang XL, Suzuki R, Lee K, Tran T, Gunton JE, Saha AK, Patti ME, Goldfine A, Ruderman NB, Gonzalez FJ, Kahn CR. Ablation of ARNT/HIF1beta in liver alters gluconeogenesis, lipogenic gene expression, and serum ketones. Cell Metabolism. 9: 428-39. PMID 19416713 DOI: 10.1016/J.Cmet.2009.04.001 |
0.252 |
|
| 2009 |
Ruderman NB, Saha AK, Vavvas D, Kurowski T, Laybutt DR, Kraegen EW. Malonyl CoA fuel sensing mechanism in muscle of insulin resistant rodents Experimental and Clinical Endocrinology & Diabetes. 105: 15-15. DOI: 10.1055/s-0029-1211825 |
0.252 |
|
| 2005 |
LeBrasseur NK, Ruderman NB. Why might thiazolidinediones increase exercise capacity in patients with type 2 diabetes? Diabetes Care. 28: 2975-7. PMID 16306565 DOI: 10.2337/Diacare.28.12.2975 |
0.251 |
|
| 2005 |
Ruderman N. Cardiorespiratory fitness attenuates mortality associated with the metabolic syndrome. Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine. 15: 282-3. PMID 16003046 DOI: 10.1097/01.Jsm.0000171885.19798.13 |
0.251 |
|
| 2005 |
Joly E, Bendayan M, Roduit R, Saha AK, Ruderman NB, Prentki M. Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes. Febs Letters. 579: 6581-6. PMID 16298369 DOI: 10.1016/J.Febslet.2005.10.050 |
0.251 |
|
| 2003 |
Panzer C, Brieke A, Ruderman N. Prevention of type 2 diabetes and its macrovascular complications: whom, when, and how should we treat? Current Opinion in Endocrinology & Diabetes. 10: 229-236. DOI: 10.1097/00132980-200302060-00005 |
0.249 |
|
| 1984 |
Schneider SH, Amorosa LF, Khachadurian AK, Ruderman NB. Studies on the mechanism of improved glucose control during regular exercise in type 2 (non-insulin-dependent) diabetes. Diabetologia. 26: 355-60. PMID 6376244 DOI: 10.1007/BF00266036 |
0.249 |
|
| 1988 |
Schneider SH, Khachadurian AK, Amorosa LF, Gavras H, Fineberg SE, Ruderman NB. Abnormal glucoregulation during exercise in type II (non-insulin-dependent) diabetes. Metabolism: Clinical and Experimental. 36: 1161-6. PMID 3316925 DOI: 10.1016/0026-0495(87)90243-5 |
0.248 |
|
| 1978 |
Goodman MN, Ruderman NB, Aoki TT. Glucose and amino acid metabolism in perfused skeletal muscle. Effect of dichloroacetate. Diabetes. 27: 1065-74. PMID 720766 DOI: 10.2337/diab.27.11.1065 |
0.244 |
|
| 1985 |
Zorzano A, Balon TW, Brady LJ, Rivera P, Garetto LP, Young JC, Goodman MN, Ruderman NB. Effects of starvation and exercise on concentrations of citrate, hexose phosphates and glycogen in skeletal muscle and heart. Evidence for selective operation of the glucose-fatty acid cycle. The Biochemical Journal. 232: 585-91. PMID 4091810 DOI: 10.1042/bj2320585 |
0.244 |
|
| 1999 |
Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F, Juhl C, ... ... Ruderman N, et al. 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia. 42: A1-A330. PMID 27770183 DOI: 10.1007/Bf03375458 |
0.243 |
|
| 1992 |
Gupta S, Sussman I, McArthur CS, Tornheim K, Cohen RA, Ruderman NB. Endothelium-dependent inhibition of Na(+)-K+ ATPase activity in rabbit aorta by hyperglycemia. Possible role of endothelium-derived nitric oxide. The Journal of Clinical Investigation. 90: 727-32. PMID 1325996 DOI: 10.1172/JCI115944 |
0.242 |
|
| 1985 |
Balon TW, Zorzano A, Goodman MN, Ruderman NB. INSULIN MODULATED THERMOGENESIS IN SKELETAL MUSCLE FOLLOWING EXERCISE IS A LOCALLY-GENERATED PHENOMENA Medicine & Science in Sports & Exercise. 17: 261. DOI: 10.1249/00005768-198504000-00354 |
0.242 |
|
| 1974 |
Ruderman NB, Ross PS, Berger M, Goodman MN. Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats. The Biochemical Journal. 138: 1-10. PMID 4275704 DOI: 10.1042/bj1380001 |
0.237 |
|
| 2013 |
Xu XJ, Pories WJ, Dohm LG, Ruderman NB. What distinguishes adipose tissue of severely obese humans who are insulin sensitive and resistant? Current Opinion in Lipidology. 24: 49-56. PMID 23298959 DOI: 10.1097/MOL.0b013e32835b465b |
0.237 |
|
| 1988 |
Schneider SH, Kim HC, Khachadurian AK, Ruderman NB. Impaired fibrinolytic response to exercise in type II diabetes: effects of exercise and physical training. Metabolism: Clinical and Experimental. 37: 924-9. PMID 3173111 DOI: 10.1016/0026-0495(88)90148-5 |
0.235 |
|
| 2010 |
Ritov VB, Menshikova EV, Azuma K, Wood R, Toledo FG, Goodpaster BH, Ruderman NB, Kelley DE. Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity. American Journal of Physiology. Endocrinology and Metabolism. 298: E49-58. PMID 19887598 DOI: 10.1152/Ajpendo.00317.2009 |
0.235 |
|
| 1986 |
Zorzano A, Balon TW, Goodman MN, Ruderman NB. Insulin and exercise stimulate muscle alpha-aminoisobutyric acid transport by a Na+-K+-ATPase independent pathway. Biochemical and Biophysical Research Communications. 134: 1342-9. PMID 2418838 DOI: 10.1016/0006-291X(86)90397-9 |
0.235 |
|
| 1985 |
Ruderman NB, Berger M. Muscle glucose oxidation. The American Journal of Physiology. 249: E433-4. PMID 4050992 DOI: 10.1152/ajpendo.1985.249.4.E433 |
0.235 |
|
| 1996 |
Kurowski TG, Saha AK, Cunningham BA, Holbert RI, Colca JR, Corkey BE, Ruderman NB. Malonyl coenzyme A and adiposity in the Dahl salt-sensitive rat: effects of pioglitazone. Metabolism: Clinical and Experimental. 45: 519-25. PMID 8609842 DOI: 10.1016/S0026-0495(96)90230-9 |
0.233 |
|
| 1981 |
Ruderman NB, Kemmer FW, Goodman MN, Berger M. Oxygen consumption in perfused skeletal muscle. Effect of perfusion with aged, fresh and aged-rejuvenated erythrocytes on oxygen consumption, tissue metabolites and inhibition of glucose utilization by acetoacetate. The Biochemical Journal. 190: 57-64. PMID 7447936 DOI: 10.1042/bj1900057 |
0.232 |
|
| 2010 |
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 464: 121-5. PMID 20203611 DOI: 10.1038/Nature08778 |
0.232 |
|
| 1982 |
Richter EA, Ruderman NB, Gavras H, Belur ER, Galbo H. Muscle glycogenolysis during exercise: dual control by epinephrine and contractions. The American Journal of Physiology. 242: E25-32. PMID 7058885 DOI: 10.1152/ajpendo.1982.242.1.E25 |
0.229 |
|
| 1990 |
Gaposchkin CG, Tornheim K, Sussman I, Ruderman NB, McCall AL. Glucose is required to maintain ATP/ADP ratio of isolated bovine cerebral microvessels. The American Journal of Physiology. 258: E543-7. PMID 2316646 DOI: 10.1152/ajpendo.1990.258.3.E543 |
0.228 |
|
| 1980 |
Goodman MN, Larsen PR, Kaplan MM, Aoki TT, Young VR, Ruderman NB. Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism. The American Journal of Physiology. 239: E277-E286. PMID 7425120 DOI: 10.1152/ajpendo.1980.239.4.e277 |
0.227 |
|
| 1981 |
Schneider SH, Komanicky PM, Goodman MN, Ruderman NB. Dichloroacetate: effects on exercise endurance in untrained rats. Metabolism: Clinical and Experimental. 30: 590-5. PMID 7231196 DOI: 10.1016/0026-0495(81)90137-2 |
0.227 |
|
| 1994 |
Gupta S, McArthur C, Grady C, Ruderman NB. Stimulation of vascular Na(+)-K(+)-ATPase activity by nitric oxide: a cGMP-independent effect. The American Journal of Physiology. 266: H2146-51. PMID 7911280 DOI: 10.1152/ajpheart.1994.266.5.H2146 |
0.227 |
|
| 1987 |
Lowell BB, Ruderman NB, Goodman MN. Regulation of myofibrillar protein degradation in rat skeletal muscle during brief and prolonged starvation. Metabolism: Clinical and Experimental. 35: 1121-7. PMID 3537631 DOI: 10.1016/0026-0495(86)90025-9 |
0.226 |
|
| 1994 |
Gupta S, McArthur C, Grady C, Ruderman NB. Role of endothelium-derived nitric oxide in stimulation of Na(+)-K(+)-ATPase activity by endothelin in rabbit aorta. The American Journal of Physiology. 266: H577-82. PMID 8141359 DOI: 10.1152/ajpheart.1994.266.2.H577 |
0.223 |
|
| 1979 |
Plovnick H, Ruderman NB, Aoki T, Chideckel EW, Poffenbarger PL. Non-beta-cell tumor hypoglycemia associated with increased nonsuppressible insulin-like protein (NSILP). The American Journal of Medicine. 66: 154-9. PMID 420243 DOI: 10.1016/0002-9343(79)90508-4 |
0.221 |
|
| 1969 |
Ruderman NB. Role of Free Fatty Acids in Glucose Homeostasis Archives of Internal Medicine. 123: 299. DOI: 10.1001/archinte.1969.00300130081012 |
0.218 |
|
| 2013 |
Nolan CJ, Ruderman NB, Prentki M. Intensive insulin for type 2 diabetes: the risk of causing harm. The Lancet. Diabetes & Endocrinology. 1: 9-10. PMID 24622256 DOI: 10.1016/S2213-8587(13)70027-5 |
0.213 |
|
| 2002 |
Peters SJ, Ruderman NB, Saha A, Dyck DJ. EFFECT OF ACUTE LEPTIN ON REGULATION OF FAT AND CARBOHYDRATE METABOLISM IN RAT SKELETAL MUSCLE Medicine & Science in Sports & Exercise. 34: S80. DOI: 10.1097/00005768-200205001-00445 |
0.212 |
|
| 2016 |
Attané C, Peyot ML, Lussier R, Poursharifi P, Zhao S, Zhang D, Morin J, Pineda M, Wang S, Dumortier O, Ruderman NB, Mitchell GA, Simons B, Madiraju SR, Joly E, et al. A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice. Diabetologia. PMID 27677764 DOI: 10.1007/S00125-016-4105-2 |
0.211 |
|
| 1993 |
Sussman I, Schultz V, Gupta S, Grady C, Ruderman NB, Tornheim K. Differential effect of metabolic fuels on the energy state and Na+-K+- ATPase in isolated cerebral microvessels American Journal of Physiology - Endocrinology and Metabolism. 265: E777-E782. PMID 7902010 DOI: 10.1152/ajpendo.1993.265.5.E777 |
0.21 |
|
| 2002 |
Gupta S, Chough E, Daley J, Oates P, Tornheim K, Ruderman NB, Keaney JF. Hyperglycemia increases endothelial superoxide that impairs smooth muscle cell Na+-K+-ATPase activity. American Journal of Physiology. Cell Physiology. 282: C560-6. PMID 11832341 DOI: 10.1152/ajpcell.00343.2001 |
0.209 |
|
| 1968 |
Ruderman NB, Lauris V. Effect of acute insulin deprivation on rat liver glucokinase. Diabetes. 17: 611-6. PMID 5681078 DOI: 10.2337/diab.17.10.611 |
0.206 |
|
| 1984 |
Goodman MN, Lowell B, Belur E, Ruderman NB. Sites of protein conservation and loss during starvation: influence of adiposity. The American Journal of Physiology. 246: E383-90. PMID 6720943 DOI: 10.1152/Ajpendo.1984.246.5.E383 |
0.206 |
|
| 1991 |
Gupta S, Ruderman NB, Cragoe EJ, Sussman I. Endothelin stimulates Na(+)-K(+)-ATPase activity by a protein kinase C-dependent pathway in rabbit aorta. The American Journal of Physiology. 261: H38-45. PMID 1650145 DOI: 10.1152/ajpheart.1991.261.1.H38 |
0.206 |
|
| 2015 |
Nolan CJ, Ruderman NB, Kahn SE, Pedersen O, Prentki M. Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686. Diabetes. 64: e38-9. PMID 26405280 DOI: 10.2337/Dbi15-0002 |
0.205 |
|
| 1993 |
Schneider SH, Khachadurian AK, Amorosa LF, Clemow L, Ruderman NB. Ten-year experience with an exercise-based outpatient life-style modification program in the treatment of diabetes mellitus. Diabetes Care. 15: 1800-10. PMID 1468318 DOI: 10.2337/diacare.15.11.1800 |
0.202 |
|
| 1986 |
McCall AL, Fixman LB, Fleming N, Tornheim K, Chick W, Ruderman NB. Chronic hypoglycemia increases brain glucose transport. The American Journal of Physiology. 251: E442-7. PMID 3532819 DOI: 10.1152/ajpendo.1986.251.4.E442 |
0.201 |
|
| 1974 |
Walser M, Lund P, Ruderman NB, Coulter AW. Synthesis of essential amino acids from their alpha-keto analogues by perfused rat liver and muscle. The Journal of Clinical Investigation. 52: 2865-77. PMID 4748513 DOI: 10.1172/JCI107483 |
0.195 |
|
| 1977 |
Ruderman NB, Schmahl FW, Goodman MN. Regulation of alanine formation and release in rat muscle in vivo: effect of starvation and diabetes. The American Journal of Physiology. 233: E109-14. PMID 888947 DOI: 10.1152/ajpendo.1977.233.2.E109 |
0.193 |
|
| 1992 |
Ruderman NB, Williamson JR, Brownlee M. Glucose and diabetic vascular disease Faseb Journal. 6: 2905-2914. PMID 1644256 DOI: 10.1096/fasebj.6.11.1644256 |
0.191 |
|
| 1988 |
McCall AL, Valente J, Cordero R, Ruderman NB, Tornheim K. Metabolic characterization of isolated cerebral microvessels: ATP and ADP concentrations. Microvascular Research. 35: 325-33. PMID 3393093 DOI: 10.1016/0026-2862(88)90087-8 |
0.184 |
|
| 2004 |
Ruderman N, Prentki M. Erratum: Amp kinase and malonyl-coa: Targets for therapy of the metabolic syndrome Nature Reviews Drug Discovery. 3: 460-460. DOI: 10.1038/nrd1412 |
0.184 |
|
| 1982 |
Goodman MN, McElaney MA, Ruderman NB. Adaptation to prolonged starvation in the rat: curtailment of skeletal muscle proteolysis. The American Journal of Physiology. 241: E321-7. PMID 7315958 DOI: 10.1152/ajpendo.1981.241.4.E321 |
0.184 |
|
| 1979 |
Ruderman NB, Ganda OP, Johansen K. The effect of physical training on glucose tolerance and plasma lipids in maturity-onset diabetes. Diabetes. 89-92. PMID 761721 DOI: 10.2337/diab.28.1.S89 |
0.182 |
|
| 1999 |
McDonnell ME, Ruderman NB. Cutting the Gordian knot: Addition of metformin to insulin therapy in a patient with uncontrolled diabetes and schizophrenia [9] Diabetes Care. 22: 1912-1913. PMID 10546035 DOI: 10.2337/diacare.22.11.1912 |
0.18 |
|
| 1975 |
Ruderman NB. Muscle amino acid metabolism and gluconeogenesis. Annual Review of Medicine. 26: 245-58. PMID 1096762 DOI: 10.1146/annurev.me.26.020175.001333 |
0.167 |
|
| 1993 |
Tesfamariam B, Gupta S, Oates PJ, Ruderman NB, Cohen RA. Reduced Na(+)-K+ pump activity in diabetic rabbit carotid artery: reversal by aldose reductase inhibition. The American Journal of Physiology. 265: H1189-94. PMID 8238405 DOI: 10.1152/ajpheart.1993.265.4.H1189 |
0.164 |
|
| 1982 |
Goodman MN, Ruderman NB. INFLUENCE OF MUSCLE USE ON AMINO ACID METABOLISM Exercise and Sport Sciences Reviews. 10: 1???26. DOI: 10.1249/00003677-198201000-00001 |
0.161 |
|
| 1976 |
Ganda OP, Ruderman NB. Muscle nitrogen metabolism in chronic hepatic insufficiency. Metabolism: Clinical and Experimental. 25: 427-35. PMID 1263837 DOI: 10.1016/0026-0495(76)90075-5 |
0.158 |
|
| 1971 |
Ruderman NB, Houghton CR, Hems R. Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. The Biochemical Journal. 124: 639-51. PMID 5135248 DOI: 10.1042/bj1240639 |
0.151 |
|
| 1980 |
Goodman MN, Ruderman NB. Starvation in the rat. I. Effect of age and obesity on organ weights, RNA, DNA, and protein. The American Journal of Physiology. 239: E269-E276. PMID 6158872 DOI: 10.1152/ajpendo.1980.239.4.e269 |
0.149 |
|
| 1979 |
Ruderman NB, Goodman MN, Conover CA, Berger M. Substrate utilization in perfused skeletal muscle. Diabetes. 13-7. PMID 761709 DOI: 10.2337/diab.28.1.S13 |
0.147 |
|
| 1981 |
Ruderman NB, Schneider SH, Berchtold P. The "metabolically-obese," normal-weight individual. The American Journal of Clinical Nutrition. 34: 1617-21. PMID 7270486 DOI: 10.1093/ajcn/34.8.1617 |
0.143 |
|
| 1988 |
Sussman I, Carson MP, McCall AL, Schultz V, Ruderman NB, Tornheim K. Energy state of bovine cerebral microvessels: Comparison of isolation methods Microvascular Research. 35: 167-178. PMID 2897072 DOI: 10.1016/0026-2862(88)90060-X |
0.142 |
|
| 1983 |
Richter EA, Ruderman NB, Galbo H. Alpha and beta adrenergic effects on metabolism in contracting, perfused muscle. Acta Physiologica Scandinavica. 116: 215-22. PMID 6132521 DOI: 10.1111/j.1748-1716.1982.tb07133.x |
0.138 |
|
| 1971 |
Houghton CR, Ruderman NB. Acetoacetate as a fuel for perfused rat skeletal muscle. The Biochemical Journal. 121: 15P-16P. PMID 5116529 DOI: 10.1042/bj1210015pb |
0.137 |
|
| 1971 |
Ruderman NB, Jones AL, Krauss RM, Shafrir E. A biochemical and morphologic study of very low density lipoproteins in carbohydrate-induced hypertriglyceridemia. The Journal of Clinical Investigation. 50: 1355-68. PMID 5578237 DOI: 10.1172/JCI106615 |
0.13 |
|
| 1985 |
Young JC, Treadway JL, Ruderman NB. EFFECT OF PRIOR EXERCISE ON DIETARY-INDUCED THERMOGENESIS Medicine & Science in Sports & Exercise. 17: 205. DOI: 10.1249/00005768-198504000-00111 |
0.13 |
|
| 1988 |
VITUG A, SCHNEIDER SH, RUDERMAN NB. Exercise and Type I Diabetes Mellitus Exercise and Sport Sciences Reviews. 16: 285???304. DOI: 10.1249/00003677-198800160-00012 |
0.125 |
|
| 1979 |
Rozovski SJ, Conover CA, Ruderman NB. Effect of diabetes on the induction of ornithine decarboxylase by refeeding. Life Sciences. 25: 553-9. PMID 491851 DOI: 10.1016/0024-3205(79)90570-8 |
0.124 |
|
| 1968 |
Richards KC, Ruderman NB, Herrera MG. Effect of oleate concentration on its metabolism by the perfused rat liver Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 152: 632-635. PMID 5656831 DOI: 10.1016/0005-2760(68)90105-7 |
0.12 |
|
| 1987 |
Balon TW, Zorzano A, Treadway JL, Goodman MN, Ruderman NB. 192 Medicine & Science in Sports & Exercise. 19: S32. DOI: 10.1249/00005768-198704001-00192 |
0.12 |
|
| 1974 |
Alberti KGMM, Iversen J, Christensen NJ, Andersson A, Jarrousse C, Andersson A, Hellerström C, Andreani D, Tamburrano G, Tamburrano S, Gambardella S, Ardill J, Montgomery DAD, Hadden DR, Assan R, ... ... Ruderman NB, et al. Tenth Annual Meeting of the European Association for the Study of Diabetes Diabetologia. 10: 357-400. DOI: 10.1007/Bf02627739 |
0.112 |
|
| 2011 |
Liesa M, Luptak I, Qin F, Hyde BB, Sahin E, Siwik DA, Zhu Z, Pimentel DR, Xu XJ, Ruderman NB, Huffman KD, Doctrow SR, Richey L, Colucci WS, Shirihai OS. Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion. Circulation. 124: 806-13. PMID 21788586 DOI: 10.1161/Circulationaha.110.003418 |
0.109 |
|
| 2012 |
Laurent G, German NJ, Saha AK, de Boer VC, Fischer F, Boanca G, Dephoure N, Vaitheesvaran B, Davies M, Gygi SP, Muoio DM, Kurland IJ, Steegborn C, Ruderman NB, Haigis MC. SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase Bmc Proceedings. 6: P30. DOI: 10.1186/1753-6561-6-S3-P30 |
0.103 |
|
| 1984 |
Ruderman NB, Haudenschild C. Diabetes as an atherogenic factor. Progress in Cardiovascular Diseases. 26: 373-412. PMID 6371895 DOI: 10.1016/0033-0620(84)90011-2 |
0.1 |
|
| 2003 |
Panzer C, Brieke A, Ruderman N. Prevention of type 2 diabetes and its macrovascular complications Current Opinion in Internal Medicine. 2: 574-581. DOI: 10.1097/00132980-200302060-00005 |
0.098 |
|
| 1986 |
Young JC, Treadway JL, Balon TW, Gavras HP, Ruderman NB. Prior exercise potentiates the thermic effect of a carbohydrate load. Metabolism: Clinical and Experimental. 35: 1048-53. PMID 3534517 DOI: 10.1016/0026-0495(86)90042-9 |
0.093 |
|
| 1979 |
Michael B, Camejo M, Jacobs J, Parker J, St Cry M, Ruderman NB. H.D.L. in diabetes. Lancet (London, England). 1: 155. PMID 84176 DOI: 10.1016/S0140-6736(79)90546-4 |
0.09 |
|
| 1971 |
Salmon MA, Esiri MM, Ruderman NB. Myopathic disorder associated with mitochondrial abnormalities, hyperglycaemia, and hyperketonaemia. Lancet (London, England). 2: 290-2. PMID 4104978 DOI: 10.1016/S0140-6736(71)91335-3 |
0.069 |
|
| 1967 |
Jones AL, Ruderman NB, Herrera MG. An electron microscopic study of lipoprotein production and release by the isolated perfused rat liver. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 123: 4-9. PMID 5924455 DOI: 10.3181/00379727-123-31388 |
0.068 |
|
| 1975 |
Aoki TT, Toews CJ, Rossini AA, Ruderman NB, Cahill GF. Glucogenic substrate levels in fasting man. Advances in Enzyme Regulation. 13: 329-36. PMID 1211290 DOI: 10.1016/0065-2571(75)90023-0 |
0.068 |
|
| 1992 |
Berger M, Horton ES, Kemmer FW, Ruderman NB. Introduction Diabetes Care. 15: 1676-1678. DOI: 10.2337/diacare.15.11.1676 |
0.015 |
|
| 1996 |
RUDERMAN NB, HALL TC. USE OF GLUCOCORTICOIDS IN THE PALLIATIVE TREATMENT OF METASTATIC BRAIN TUMORS. Cancer. 18: 298-306. PMID 14264031 DOI: 10.1002/1097-0142(196503)18:3<298::AID-CNCR2820180306>3.0.CO;2-H |
0.012 |
|
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