Reuben J. Shaw - Related publications

Biology University of California, San Diego, La Jolla, CA 
Molecular Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Molina E, Hong L, Chefetz I. NUAK Kinases: Brain-Ovary Axis. Cells. 10. PMID 34685740 DOI: 10.3390/cells10102760   
2021 Lin ZY, Yun QZ, Wu L, Zhang TW, Yao TZ. Pharmacological basis and new insights of deguelin concerning its anticancer effects. Pharmacological Research. 105935. PMID 34644595 DOI: 10.1016/j.phrs.2021.105935   
2021 Fan Y, Ren X, Wang Y, Xu E, Wang S, Ge R, Liu Y. Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway . Oncology Letters. 22: 852. PMID 34733370 DOI: 10.3892/ol.2021.13113   
2021 Zhao M, Finlay D, Kwong E, Liddington R, Viollet B, Sasaoka N, Vuori K. Cell adhesion suppresses autophagy via Src/FAK-mediated phosphorylation and inhibition of AMPK. Cellular Signalling. 89: 110170. PMID 34673141 DOI: 10.1016/j.cellsig.2021.110170   
2021 Ramadan M, A M M Elshaier Y, Aly AA, Abdel-Aziz M, Fathy HM, Brown AB, Pridgen JR, Dalby KN, Kaoud TS. Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation. Bioorganic Chemistry. 116: 105344. PMID 34598088 DOI: 10.1016/j.bioorg.2021.105344   
2021 Yuan C, Chen G, Jing C, Liu M, Liang B, Gong G, Yu M. Eriocitrin, a dietary flavonoid suppressed cell proliferation, induced apoptosis through modulation of JAK2/STAT3 and JNK/p38 MAPKs signaling pathway in MCF-7 cells. Journal of Biochemical and Molecular Toxicology. e22943. PMID 34724282 DOI: 10.1002/jbt.22943   
2021 Prasher P, Sharma M, Chan Y, Singh SK, Anand K, Dureja H, Jha NK, Gupta G, Zacconi F, Chellappan DK, Dua K. Recent Trends in rationally designed molecules as kinase inhibitors. Current Medicinal Chemistry. PMID 34766883 DOI: 10.2174/0929867328666211111161811   
2021 Mathien S, Tesnière C, Meloche S. Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacological Reviews. 73: 263-296. PMID 34732541 DOI: 10.1124/pharmrev.120.000170   
2021 Zhang Z, Ran Y, Xu L, Pan Z, Xie Y. High-dose dexamethasone injection disordered metabolism and multiple protein kinases expression in the mouse kidney. Bioscience Reports. PMID 34735568 DOI: 10.1042/BSR20211847   
2021 Nam HK, Jeong SR, Pyo MC, Ha SK, Nam MH, Lee KW. Methylglyoxal-Derived Advanced Glycation End Products (AGE4) Promote Cell Proliferation and Survival in Renal Cell Carcinoma Cells through the RAGE/Akt/ERK Signaling Pathways. Biological & Pharmaceutical Bulletin. 44: 1697-1706. PMID 34719646 DOI: 10.1248/bpb.b21-00382   
2021 Iannetta AA, Minton NE, Uitenbroek AA, Little JL, Stanton CR, Kristich CJ, Hicks LM. IreK-Mediated, Cell Wall-Protective Phosphorylation in . Journal of Proteome Research. 20: 5131-5144. PMID 34672600 DOI: 10.1021/acs.jproteome.1c00635   
2021 Agnihotri SK, Kar P, Singh M, Pant G, Mitra K, Bhatt MLB, Sachdev M. Modulation of protein phosphatase 1 gamma 2 during cell division of cervical cancer HeLa cells. Contemporary Oncology (Poznan, Poland). 25: 125-132. PMID 34667439 DOI: 10.5114/wo.2021.107745   
2021 Saraon P, Snider J, Schormann W, Rai A, Radulovich N, Sánchez-Osuna M, Coulombe-Huntington J, Huard C, Mohammed M, Lima-Fernandes E, Thériault B, Halabelian L, Chan M, Joshi D, Drecun L, et al. Chemical genetics screen identifies COPB2 tool compounds that alters ER stress response and induces RTK dysregulation in lung cancer cells. Journal of Molecular Biology. 167294. PMID 34662547 DOI: 10.1016/j.jmb.2021.167294   
2021 He L, Jhong JH, Chen Q, Huang KY, Strittmatter K, Kreuzer J, DeRan M, Wu X, Lee TY, Slavov N, Haas W, Marneros AG. Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. Cell Reports. 37: 109955. PMID 34731634 DOI: 10.1016/j.celrep.2021.109955   
2021 Xu P, Zhao Y, Yu T, Yu Y, Ni X, Wang H, Sun L, Han P, Wang L, Sun T, Liu X, Zhou H, Peng J, Hou M, Hou Y, et al. Atorvastatin restores imbalance of cluster of differentiation 4 (CD4) T cells in immune thrombocytopenia in vivo and in vitro. British Journal of Haematology. PMID 34825359 DOI: 10.1111/bjh.17938   
2021 Caeser R, Hulton C, Costa E, Durani V, Little M, Chen X, Tischfield SE, Asher M, Kombak FE, Chavan SS, Shah NS, Ciampricotti M, de Stanchina E, Poirier JT, Rudin CM, et al. MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer. Iscience. 24: 103224. PMID 34712921 DOI: 10.1016/j.isci.2021.103224   
2021 Zhi TX, Liu KQ, Cai KY, Zhao YC, Li ZW, Wang X, He XH, Sun XY. Anti-Lung Cancer Activities of 1,2,3-Triazole Curcumin Derivatives via Regulation of the MAPK/NF-κB/STAT3 Signaling Pathways. Chemmedchem. PMID 34773680 DOI: 10.1002/cmdc.202100676   
2021 Wan Y, Wang J, Xu JF, Tang F, Chen L, Tan YZ, Rao CL, Ao H, Peng C. and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects. Journal of Ginseng Research. 45: 617-630. PMID 34764717 DOI: 10.1016/j.jgr.2021.03.001   
2021 Bhat SS, Prasad SK, Shivamallu C, Prasad KS, Syed A, Reddy P, Cull CA, Amachawadi RG. Genistein: A Potent Anti-Breast Cancer Agent. Current Issues in Molecular Biology. 43: 1502-1517. PMID 34698063 DOI: 10.3390/cimb43030106   
2021 M Gagné L, Morin N, Lavoie N, Bisson N, Lambert JP, Mallette FA, Huot MÉ. Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling. The Journal of Biological Chemistry. 297: 101291. PMID 34634301 DOI: 10.1016/j.jbc.2021.101291   
2021 Heidorn-Czarna M, Heidorn HM, Fernando S, Sanislav O, Jarmuszkiewicz W, Mutzel R, Fisher PR. Chronic Activation of AMPK Induces Mitochondrial Biogenesis through Differential Phosphorylation and Abundance of Mitochondrial Proteins in . International Journal of Molecular Sciences. 22. PMID 34769115 DOI: 10.3390/ijms222111675   
2021 Padros J, Chatel G, Caron M. Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells. Journal of Visualized Experiments : Jove. PMID 34570089 DOI: 10.3791/62915   
2021 Lin HH, Hsieh MC, Wang CP, Yu PR, Lee MS, Chen JH. Anti-Atherosclerotic Effect of Gossypetin on Abnormal Vascular Smooth Muscle Cell Proliferation and Migration. Antioxidants (Basel, Switzerland). 10. PMID 34572989 DOI: 10.3390/antiox10091357   
2021 Diehl JN, Klomp JE, Snare KR, Hibshman PS, Blake DR, Kaiser ZD, Gilbert TSK, Baldelli E, Pierobon M, Papke B, Yang R, Hodge RG, Rashid NU, Petricoin EF, Herring LE, et al. The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer. The Journal of Biological Chemistry. 101335. PMID 34688654 DOI: 10.1016/j.jbc.2021.101335   
2021 Chen PH, Hu Z, An E, Okeke I, Zheng S, Luo X, Gong A, Jaime-Figueroa S, Crews CM. Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). Acs Chemical Biology. PMID 34780684 DOI: 10.1021/acschembio.1c00693   
2021 Newport E, Pedrosa AR, Lees D, Dukinfield M, Carter E, Gomez-Escudero J, Casado P, Rajeeve V, Reynolds LE, Cutillas P, Duffy SW, Delgado BL, Hodivala-Dilke K. Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth. The Journal of Pathology. PMID 34743335 DOI: 10.1002/path.5833   
2021 Zhang T, Liu Q, Gao W, Sehgal SA, Wu H. The multifaceted regulation of mitophagy by endogenous metabolites. Autophagy. 1-24. PMID 34583624 DOI: 10.1080/15548627.2021.1975914   
2021 Elksnis A, Schiffer TA, Palm F, Wang Y, Cen J, Turpaev K, Ngamjariyawat A, Younis S, Huang S, Shen Y, Leng Y, Bergsten P, Karlsborn T, Welsh N, Wang X. Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK. Clinical Science (London, England : 1979). 135: 2243-2263. PMID 34569605 DOI: 10.1042/CS20210604   
2021 Ortega MA, Fraile-Martínez O, García-Montero C, Ruiz-Grande F, Barrena S, Montoya H, Pekarek L, Zoullas S, Alvarez-Mon MA, Sainz F, Asúnsolo A, Acero J, Álvarez-Mon M, Buján J, García-Honduvilla N, et al. Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall. The Journal of International Medical Research. 49: 3000605211041275. PMID 34590920 DOI: 10.1177/03000605211041275   
2021 Rabhi N, Desevin K, Cortez BN, Hekman R, Lin JZ, Emili A, Farmer SR. The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice. Scientific Reports. 11: 20365. PMID 34645915 DOI: 10.1038/s41598-021-99871-z   
2021 Xie Y, Mu C, Kazybay B, Sun Q, Kutzhanova A, Nazarbek G, Xu N, Nurtay L, Wang Q, Amin A, Li X. Network pharmacology and experimental investigation of extract targeted kinase with herbzyme activity for potent drug delivery. Drug Delivery. 28: 2187-2197. PMID 34662244 DOI: 10.1080/10717544.2021.1977422   
2021 Hollenstein DM, Gérecová G, Romanov N, Ferrari J, Veis J, Janschitz M, Beyer R, Schüller C, Ogris E, Hartl M, Ammerer G, Reiter W. A phosphatase-centric mechanism drives stress signaling response. Embo Reports. e52476. PMID 34558777 DOI: 10.15252/embr.202152476   
2021 Sahin KB, Shah ET, Ferguson GP, Molloy C, Kalita-de Croft P, Hayes SA, Hudson A, Colvin E, Kamitakahara H, Harvie R, Hasovits C, Khan T, Duijf PHG, Howell VM, He Y, et al. Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer. Cancers. 13. PMID 34572879 DOI: 10.3390/cancers13184651   
2021 Korkmaz R, Yüksek V, Dede S. The Effects of Sodium Fluoride (NaF) Treatment on the PI3K/Akt Signal Pathway in NRK-52E Cells. Biological Trace Element Research. PMID 34569011 DOI: 10.1007/s12011-021-02927-4   
2021 Roffey SE, Litchfield DW. CK2 Regulation: Perspectives in 2021. Biomedicines. 9. PMID 34680478 DOI: 10.3390/biomedicines9101361   
2021 Zhu DW, Yu Q, Sun JJ, Shen YH. Evaluating the Therapeutic Mechanisms of Selected Active Compounds in Thunb. in Pulmonary Fibrosis Network Pharmacology Analysis. Frontiers in Pharmacology. 12: 733618. PMID 34658873 DOI: 10.3389/fphar.2021.733618   
2021 Farooq M, Khan AW, Kim MS, Choi S. The Role of Fibroblast Growth Factor (FGF) Signaling in Tissue Repair and Regeneration. Cells. 10. PMID 34831463 DOI: 10.3390/cells10113242   
2021 Islam R, Rahaman M, Hoque H, Hasan N, Prodhan SH, Ruhama A, Jewel NA. Computational and structural based approach to identify malignant nonsynonymous single nucleotide polymorphisms associated with CDK4 gene. Plos One. 16: e0259691. PMID 34735543 DOI: 10.1371/journal.pone.0259691   
2021 Tian X, Zhang S, Zhou L, Seyhan AA, Hernandez Borrero L, Zhang Y, El-Deiry WS. Targeting the Integrated Stress Response in Cancer Therapy. Frontiers in Pharmacology. 12: 747837. PMID 34630117 DOI: 10.3389/fphar.2021.747837   
2021 Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM. MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. Journal of Proteomics. 104424. PMID 34775100 DOI: 10.1016/j.jprot.2021.104424   
2021 Pei H, Wu S, Zheng L, Wang H, Zhang X. Identification of the active compounds and their mechanisms of medicinal and edible Shanzha based on network pharmacology and molecular docking. Journal of Food Biochemistry. e14020. PMID 34825377 DOI: 10.1111/jfbc.14020   
2021 Wang W, Gao W, Zhu Q, Alasbahi A, Seki E, Yang L. TAK1: A Molecular Link Between Liver Inflammation, Fibrosis, Steatosis, and Carcinogenesis. Frontiers in Cell and Developmental Biology. 9: 734749. PMID 34722513 DOI: 10.3389/fcell.2021.734749   
2021 Lee CJ, Lee GE, An HJ, Cho ES, Chen W, Lee JY, Kang HC, Lee HS, Cho YY. F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2. Journal of Cancer Prevention. 26: 174-182. PMID 34703820 DOI: 10.15430/JCP.2021.26.3.174   
2021 Olazábal-Morán M, Sánchez-Ortega M, Martínez-Muñoz L, Hernández C, Rodríguez MS, Mellado M, Carrera AC. Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL. Cells. 10. PMID 34831026 DOI: 10.3390/cells10112803   
2021 Kim JY, Park HH, Yong TS, Jeon SH. Lithium chloride inhibits the migration and invasion of osteosarcoma cells by blocking nuclear translocation of phospho-Erk. Biochemical and Biophysical Research Communications. 581: 74-80. PMID 34656851 DOI: 10.1016/j.bbrc.2021.10.025   
2021 Miao X, Liu C, Jiang Y, Wang Y, Kong D, Wu Z, Wang X, Tian R, Yu X, Zhu X, Gong W. BET protein inhibition evidently enhances sensitivity to PI3K/mTOR dual inhibition in intrahepatic cholangiocarcinoma. Cell Death & Disease. 12: 1020. PMID 34716294 DOI: 10.1038/s41419-021-04305-3   
2021 Huang A, Zeng P, Li Y, Lu W, Lai Y. LY294002 Is a Promising Inhibitor to Overcome Sorafenib Resistance in FLT3-ITD Mutant AML Cells by Interfering With PI3K/Akt Signaling Pathway. Frontiers in Oncology. 11: 782065. PMID 34820336 DOI: 10.3389/fonc.2021.782065   
2021 Yang Q, Ma Q, Xu J, Liu Z, Mao X, Zhou Y, Cai Y, Da Q, Hong M, Weintraub NL, Fulton DJ, Belin de Chantemèle EJ, Huo Y. Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD-fed mice. British Journal of Pharmacology. PMID 34796475 DOI: 10.1111/bph.15742   
2021 Zhang Z, Zeng D, Zhang W, Chen A, Lei J, Liu F, Deng B, Zhuo J, He B, Yan M, Lei X, Wang S, Lam EW, Liu Q, Wang Z. Modulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition. Cell Death & Disease. 12: 893. PMID 34593753 DOI: 10.1038/s41419-021-04190-w   
2021 Jee W, Lee SH, Ko HM, Jung JH, Chung WS, Jang HJ. Anti-Obesity Effect of Polygalin C Isolated from Houtt. via Suppression of the Adipogenic and Lipogenic Factors in 3T3-L1 Adipocytes. International Journal of Molecular Sciences. 22. PMID 34638751 DOI: 10.3390/ijms221910405