| Year |
Citation |
Score |
| 2024 |
Li Z, Liu HY, He Z, Chakravarty A, Golden RP, Jiang Z, You I, Yue H, Donovan KA, Du G, Che J, Tse J, Che I, Lu W, Fischer ES, et al. Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2405829. PMID 39145423 DOI: 10.1002/advs.202405829 |
0.326 |
|
| 2024 |
Ji W, Du G, Jiang J, Lu W, Mills CE, Yuan L, Jiang F, He Z, Bradshaw GA, Chung M, Jiang Z, Byun WS, Hinshaw SM, Zhang T, Gray NS. Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7). European Journal of Medicinal Chemistry. 276: 116613. PMID 39004018 DOI: 10.1016/j.ejmech.2024.116613 |
0.653 |
|
| 2024 |
Li Z, Liu HY, He Z, Chakravarty A, Golden RP, Jiang Z, You I, Yue H, Donovan KA, Du G, Che J, Tse J, Che I, Lu W, Fischer ES, et al. Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Biorxiv : the Preprint Server For Biology. PMID 38854003 DOI: 10.1101/2024.06.01.596987 |
0.496 |
|
| 2022 |
Zerfas BL, Huerta F, Liu H, Du G, Gray NS, Jones LH, Nowak RP. Advancing targeted protein degrader discovery by measuring cereblon engagement in cells. Methods in Enzymology. 681: 169-188. PMID 36764756 DOI: 10.1016/bs.mie.2022.08.013 |
0.495 |
|
| 2022 |
Du G, Jiang J, Henning NJ, Safaee N, Koide E, Nowak RP, Donovan KA, Yoon H, You I, Yue H, Eleuteri NA, He Z, Li Z, Huang HT, Che J, et al. Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell Chemical Biology. PMID 36070758 DOI: 10.1016/j.chembiol.2022.08.003 |
0.521 |
|
| 2021 |
Powell CE, Du G, Bushman JW, He Z, Zhang T, Fischer ES, Gray NS. Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390. PMID 34458741 DOI: 10.1039/d0md00382d |
0.766 |
|
| 2021 |
Du G, Jiang J, Wu Q, Henning NJ, Donovan KA, Yue H, Che J, Lu W, Fischer ES, Bardeesy N, Zhang T, Gray NS. Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angewandte Chemie (International Ed. in English). PMID 33915015 DOI: 10.1002/anie.202101328 |
0.564 |
|
| 2020 |
Powell CE, Du G, Che J, He Z, Donovan KA, Yue H, Wang ES, Nowak RP, Zhang T, Fischer ES, Gray NS. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. Acs Chemical Biology. PMID 32865967 DOI: 10.1021/Acschembio.0C00520 |
0.771 |
|
| 2020 |
Gurbani D, Du G, Henning NJ, Rao S, Bera AK, Zhang T, Gray NS, Westover KD. Structure and Characterization of a Covalent Inhibitor of Src Kinase. Frontiers in Molecular Biosciences. 7: 81. PMID 32509799 DOI: 10.3389/Fmolb.2020.00081 |
0.788 |
|
| 2020 |
Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, et al. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. PMID 32109415 DOI: 10.1016/J.Cell.2020.02.012 |
0.44 |
|
| 2020 |
Du G, Rao S, Gurbani D, Henning NJ, Jiang J, Che J, Yang A, Ficarro SB, Marto JA, Aguirre AJ, Sorger PK, Westover KD, Zhang T, Gray NS. Structure-based design of a potent and selective covalent inhibitor for SRC kinase that targets a p-Loop cysteine. Journal of Medicinal Chemistry. PMID 31935084 DOI: 10.1021/Acs.Jmedchem.9B01502 |
0.81 |
|
| 2019 |
de Wispelaere M, Du G, Donovan KA, Zhang T, Eleuteri NA, Yuan JC, Kalabathula J, Nowak RP, Fischer ES, Gray NS, Yang PL. Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations. Nature Communications. 10: 3468. PMID 31371704 DOI: 10.1038/S41467-019-11429-W |
0.547 |
|
| 2019 |
Scott DA, Hatcher JM, Liu H, Fu M, Du G, Fontán L, Us I, Casalena G, Qiao Q, Wu H, Melnick A, Gray NS. Quinoline and thiazolopyridine allosteric inhibitors of MALT1. Bioorganic & Medicinal Chemistry Letters. PMID 31129051 DOI: 10.1016/J.Bmcl.2019.05.040 |
0.735 |
|
| 2019 |
Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Li T, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, et al. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chemical Biology. PMID 30982749 DOI: 10.1016/J.Chembiol.2019.02.021 |
0.778 |
|
| 2019 |
Hatcher JM, Du G, Fontán L, Us I, Qiao Q, Chennamadhavuni S, Shao J, Wu H, Melnick A, Gray NS, Scott DA. Peptide-based covalent inhibitors of MALT1 paracaspase. Bioorganic & Medicinal Chemistry Letters. PMID 30954428 DOI: 10.1016/J.Bmcl.2019.03.046 |
0.757 |
|
| 2019 |
Rao S, Du G, Hafner M, Subramanian K, Sorger PK, Gray NS. A multi-targeted probe-based strategy to identify signaling vulnerabilities in cancers. The Journal of Biological Chemistry. PMID 30858179 DOI: 10.1074/Jbc.Ra118.006805 |
0.766 |
|
| 2019 |
Fontan L, Hatcher J, Scott D, Qiao Q, Us I, Du G, Durant M, Wilson J, Wu H, Gray N, Melnick A. Chemically Induced Degradation of MALT1 to Treat B-Cell Lymphomas Blood. 134: 2073-2073. DOI: 10.1182/Blood-2019-130666 |
0.797 |
|
| 2018 |
Fontán L, Qiao Q, Hatcher JM, Casalena G, Us I, Teater M, Durant M, Du G, Xia M, Bilchuk N, Chennamadhavuni S, Palladino G, Inghirami G, Philippar U, Wu H, et al. Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. The Journal of Clinical Investigation. PMID 30024860 DOI: 10.1172/Jci99436 |
0.748 |
|
| 2017 |
Rao S, Li T, Everley R, Du G, Sorger P, Gray N. Abstract 1222: Developing kinase inhibitors with polypharmacological profiles for the treatment of resistant cancers Cancer Research. 77: 1222-1222. DOI: 10.1158/1538-7445.Am2017-1222 |
0.772 |
|
| 2016 |
Tan L, Gurbani D, Weisberg EL, Jones DS, Rao S, Singer WD, Bernard FM, Mowafy S, Jenney A, Du G, Nonami A, Griffin JD, Lauffenburger DA, Westover KD, Sorger PK, et al. Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28038940 DOI: 10.1016/J.Bmc.2016.11.034 |
0.808 |
|
| 2016 |
Tan L, Gurbani D, Weisberg EL, Hunter JC, Li L, Jones DS, Ficarro SB, Mowafy S, Tam CP, Rao S, Du G, Griffin JD, Sorger PK, Marto JA, Westover KD, et al. Structure-guided development of covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28011204 DOI: 10.1016/J.Bmc.2016.11.035 |
0.807 |
|
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