Hanry Yu, Ph.D. - Publications

Affiliations: 
Physiology National University of Singapore, Singapore, Singapore 
Area:
ER dynamics, cell motility, microscopy, liver diseases, biomaterials, tissue engineering
Website:
http://hanrylab.med.nus.edu.sg

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chua ACY, Ananthanarayanan A, Ong JJY, Wong JY, Yip A, Singh NH, Qu Y, Dembele L, McMillian M, Ubalee R, Davidson S, Tungtaeng A, Imerbsin R, Gupta K, Andolina C, ... ... Yu H, et al. Hepatic spheroids used as an in vitro model to study malaria relapse. Biomaterials. 216: 119221. PMID 31195301 DOI: 10.1016/j.biomaterials.2019.05.032  0.56
2019 Ni M, Zhuo S, Iliescu C, So PTC, Mehta JS, Yu H, Hauser CAE. Self-assembling amyloid-like peptides as exogenous second harmonic probes for bioimaging applications. Journal of Biophotonics. e201900065. PMID 31162811 DOI: 10.1002/jbio.201900065  0.68
2019 Sun M, Wong JY, Nugraha B, Ananthanarayanan A, Liu Z, Lee F, Gupta K, Fong ELS, Huang X, Yu H. Cleavable cellulosic sponge for functional hepatic cell culture and retrieval. Biomaterials. 201: 16-32. PMID 30784769 DOI: 10.1016/j.biomaterials.2019.01.046  0.56
2018 Tasnim F, Xing J, Huang X, Mo S, Wei X, Tan MH, Yu H. Generation of mature kupffer cells from human induced pluripotent stem cells. Biomaterials. 192: 377-391. PMID 30497023 DOI: 10.1016/j.biomaterials.2018.11.016  0.6
2018 Yu Y, Wang J, Ng CW, Ma Y, Mo S, Fong ELS, Xing J, Song Z, Xie Y, Si K, Wee A, Welsch RE, So PTC, Yu H. Deep learning enables automated scoring of liver fibrosis stages. Scientific Reports. 8: 16016. PMID 30375454 DOI: 10.1038/s41598-018-34300-2  0.8
2018 Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, ... ... Yu H, et al. PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy. Cell Research. PMID 29934616 DOI: 10.1038/s41422-018-0056-0  0.84
2018 Fong ELS, Toh TB, Lin QXX, Liu Z, Hooi L, Rashid MBMA, Benoukraf T, Chow EK, Huynh TH, Yu H. Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel. Data in Brief. 18: 594-606. PMID 29900213 DOI: 10.1016/j.dib.2018.03.045  0.48
2018 Wang P, Lu YC, Wang J, Wang L, Yu H, Li YF, Kong A, Chan J, Lee S. Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3σ. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 47: 356-367. PMID 29768267 DOI: 10.1159/000489812  0.8
2018 Toh YC, Raja A, Yu H, van Noort D. A 3D Microfluidic Model to Recapitulate Cancer Cell Migration and Invasion. Bioengineering (Basel, Switzerland). 5. PMID 29642502 DOI: 10.3390/bioengineering5020029  0.88
2018 Luo X, Gupta K, Ananthanarayanan A, Wang Z, Xia L, Li A, Sakban RB, Liu S, Yu H. Directed Differentiation of Adult Liver Derived Mesenchymal Like Stem Cells into Functional Hepatocytes. Scientific Reports. 8: 2818. PMID 29434311 DOI: 10.1038/s41598-018-20304-5  0.88
2018 Yu Y, Ananthanarayanan A, Singh NH, Hong X, Sakban RB, Mittal N, Xiaobei L, Robens J, Xia L, McMillian M, Yu H. TGFβ1-mediated suppression of cytochrome P450(CYP) induction responses in rat hepatocyte-fibroblast co-cultures. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 29366910 DOI: 10.1016/j.tiv.2018.01.015  0.88
2018 Fong ELS, Toh TB, Lin X, Liu Z, Hooi L, Mohd Abdul Rashid MB, Benoukraf T, Chow EK, Huynh TH, Yu H. Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer. Biomaterials. 159: 229-240. PMID 29353739 DOI: 10.1016/j.biomaterials.2017.12.026  0.48
2017 Li H, Venkatraman L, Narmada BC, White JK, Yu H, Tucker-Kellogg L. Computational analysis reveals the coupling between bistability and the sign of a feedback loop in a TGF-β1 activation model. Bmc Systems Biology. 11: 136. PMID 29322934 DOI: 10.1186/s12918-017-0508-z  0.84
2017 Yu F, Deng R, Hao Tong W, Huan L, Chan Way N, IslamBadhan A, Iliescu C, Yu H. A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing. Scientific Reports. 7: 14528. PMID 29109520 DOI: 10.1038/s41598-017-13848-5  0.36
2017 Xing J, Cao Y, Yu Y, Li H, Song Z, Yu H. In Vitro Micropatterned Human Pluripotent Stem Cell Test (µP-hPST) for Morphometric-Based Teratogen Screening. Scientific Reports. 7: 8491. PMID 28819231 DOI: 10.1038/s41598-017-09178-1  0.84
2017 Song Z, Gupta K, Ng IC, Xing J, Yang YA, Yu H. MECHANOSENSING IN LIVER REGENERATION. Seminars in Cell & Developmental Biology. PMID 28768152 DOI: 10.1016/j.semcdb.2017.07.041  0.84
2017 Yan J, Yu Y, Kang JW, Tam ZY, Xu S, Fong ELS, Singh SP, Song Z, Tucker-Kellogg L, So PTC, Yu H. Development of a classification model for non-alcoholic steatohepatitis (NASH) using confocal Raman micro-spectroscopy. Journal of Biophotonics. PMID 28635128 DOI: 10.1002/jbio.201600303  0.72
2017 Ong LJY, Chong LH, Jin L, Singh PK, Lee PS, Yu H, Ananthanarayanan A, Leo HL, Toh YC. A pump-free microfluidic 3D perfusion platform for the efficient differentiation of human hepatocyte-like cells. Biotechnology and Bioengineering. PMID 28542705 DOI: 10.1002/bit.26341  0.88
2017 Yu F, Zhuo S, Qu Y, Choudhury D, Wang Z, Iliescu C, Yu H. On chip two-photon metabolic imaging for drug toxicity testing. Biomicrofluidics. 11: 034108. PMID 28529673 DOI: 10.1063/1.4983615  0.68
2017 Choudhury Y, Toh YC, Xing J, Qu Y, Poh J, Li H, Tan HS, Kanesvaran R, Yu H, Tan MH. Corrigendum: Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity. Scientific Reports. 7: 46391. PMID 28440337 DOI: 10.1038/srep46391  0.88
2017 Narmada BC, Goh YT, Li H, Sinha S, Yu H, Cheung C. Human Stem Cell-Derived Endothelial-Hepatic Platform for Efficacy Testing of Vascular-Protective Metabolites from Nutraceuticals. Stem Cells Translational Medicine. 6: 851-863. PMID 28297582 DOI: 10.5966/sctm.2016-0129  0.84
2017 Fong EL, Toh TB, Yu H, Chow EK. 3D Culture as a Clinically Relevant Model for Personalized Medicine. Slas Technology. 2472630317697251. PMID 28277923 DOI: 10.1177/2472630317697251  0.6
2017 Lou YR, Toh TC, Tee YH, Yu H. 25-Hydroxyvitamin D3 induces osteogenic differentiation of human mesenchymal stem cells. Scientific Reports. 7: 42816. PMID 28211493 DOI: 10.1038/srep42816  0.44
2017 Gupta K, Li Q, Fan JJ, Fong EL, Song Z, Mo S, Tang H, Ng IC, Ng CW, Pawijit P, Zhuo S, Dong CY, Low BC, Wee A, Dan YY, ... ... Yu H, et al. Actomyosin Contractility Drives Bile Regurgitation as an Early Response During Obstructive Cholestasis. Journal of Hepatology. PMID 28189756 DOI: 10.1016/j.jhep.2017.01.026  0.84
2017 Choudhury Y, Toh YC, Xing J, Qu Y, Poh J, Huan L, Tan HS, Kanesvaran R, Yu H, Tan MH. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity. Scientific Reports. 7: 41238. PMID 28120901 DOI: 10.1038/srep41238  0.88
2016 Domian IJ, Yu H, Mittal N. On Materials for Cardiac Tissue Engineering. Advanced Healthcare Materials. PMID 27774763 DOI: 10.1002/adhm.201600768  0.56
2016 Zhu L, Xia H, Wang Z, Fong EL, Fan J, Tong WH, Seah YP, Zhang W, Li Q, Yu H. A vertical-flow bioreactor array compacts hepatocytes for enhanced polarity and functions. Lab On a Chip. 16: 3898-3908. PMID 27722715 DOI: 10.1039/c6lc00811a  0.6
2016 Song Z, Shanmugam MK, Yu H, Sethi G. Butein and Its Role in Chronic Diseases. Advances in Experimental Medicine and Biology. 928: 419-433. PMID 27671826 DOI: 10.1007/978-3-319-41334-1_17  0.6
2016 Fong EL, Harrington DA, Farach-Carson MC, Yu H. Heralding a new paradigm in 3D tumor modeling. Biomaterials. 108: 197-213. PMID 27639438 DOI: 10.1016/j.biomaterials.2016.08.052  0.48
2016 Koh WL, Tham PH, Yu H, Leo HL, Yong Kah JC. Aggregation and protein corona formation on gold nanoparticles affect viability and liver functions of primary rat hepatocytes. Nanomedicine (London, England). PMID 27527273 DOI: 10.2217/nnm-2016-0173  0.88
2016 Ng IC, Pawijit P, Teo LY, Li H, Lee SY, Yu H. Kinectin-dependent endoplasmic reticulum transport supports focal complex maturation for chemotaxis in shallow gradients. Journal of Cell Science. PMID 27221621 DOI: 10.1242/jcs.181768  0.84
2016 Ni M, Zhuo S, So PT, Yu H. Fluorescent probes for nanoscopy: four categories and multiple possibilities. Journal of Biophotonics. PMID 27221311 DOI: 10.1002/jbio.201600042  0.88
2016 Tasnim F, Toh YC, Qu Y, Li H, Phan D, Narmada BC, Ananthanarayanan A, Mittal N, Meng RQ, Yu H. Functionally enhanced human stem cell derived hepatocytes in galactosylated cellulosic sponges for hepatotoxicity testing. Molecular Pharmaceutics. PMID 27157693 DOI: 10.1021/acs.molpharmaceut.6b00119  0.88
2015 Tong WH, Fang Y, Yan J, Hong X, Hari Singh N, Wang SR, Nugraha B, Xia L, Fong EL, Iliescu C, Yu H. Constrained spheroids for prolonged hepatocyte culture. Biomaterials. 80: 106-120. PMID 26708088 DOI: 10.1016/j.biomaterials.2015.11.036  0.44
2015 Kathuria H, Kochhar JS, Fong MH, Hashimoto M, Iliescu C, Yu H, Kang L. Polymeric Microneedle Array Fabrication by Photolithography. Journal of Visualized Experiments : Jove. PMID 26650548 DOI: 10.3791/52914  0.36
2015 Tasnim F, Phan D, Toh YC, Yu H. Cost-effective differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules. Biomaterials. 70: 115-25. PMID 26310107 DOI: 10.1016/j.biomaterials.2015.08.002  0.88
2015 Xing J, Toh YC, Xu S, Yu H. Corrigendum: A method for human teratogen detection by geometrically confined cell differentiation and migration. Scientific Reports. 5: 12387. PMID 26237348 DOI: 10.1038/srep12387  0.88
2015 Tan WJ, Yan J, Xu S, Thike AA, Bay BH, Yu H, Tan MH, Tan PH. Second harmonic generation microscopy is a novel technique for differential diagnosis of breast fibroepithelial lesions. Journal of Clinical Pathology. PMID 26209730 DOI: 10.1136/jclinpath-2015-203231  0.44
2015 Xia L, Hong X, Sakban RB, Qu Y, Singh NH, McMillian M, Dallas S, Silva J, Sensenhauser C, Zhao S, Lim HK, Yu H. Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model. Journal of Applied Toxicology : Jat. PMID 26201057 DOI: 10.1002/jat.3189  0.44
2015 Xu S, Kang CH, Gou X, Peng Q, Yan J, Zhuo S, Cheng CL, He Y, Kang Y, Xia W, So PT, Welsch R, Rajapakse JC, Yu H. Quantification of liver fibrosis via second harmonic imaging of the Glisson's capsule from liver surface. Journal of Biophotonics. PMID 26131709 DOI: 10.1002/jbio.201500001  0.44
2015 Xing J, Toh YC, Xu S, Yu H. A method for human teratogen detection by geometrically confined cell differentiation and migration. Scientific Reports. 5: 10038. PMID 25966467 DOI: 10.1038/srep10038  0.88
2015 Toh YC, Xing J, Yu H. Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation. Biomaterials. 50: 87-97. PMID 25736499 DOI: 10.1016/j.biomaterials.2015.01.019  0.88
2015 Raja AM, Xu S, Zhuo S, Tai DC, Sun W, So PT, Welsch RE, Chen CS, Yu H. Journal of Biophotonics. 9999. PMID 25597396 DOI: 10.1002/jbio.201400079  0.44
2015 Wang Z, Luo X, Anene-Nzelu C, Yu Y, Hong X, Singh NH, Xia L, Liu S, Yu H. HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening. Journal of Applied Toxicology : Jat. 35: 909-17. PMID 25512232 DOI: 10.1002/jat.3090  0.96
2014 Yan J, Kang Y, Xu S, Ong LL, Zhuo S, Bunte RM, Chen N, Asada HH, So PT, Wanless IR, Yu H. In vivo label-free quantification of liver microcirculation using dual-modality microscopy. Journal of Biomedical Optics. 19: 116006. PMID 25388810 DOI: 10.1117/1.JBO.19.11.116006  0.44
2014 Iliescu C, M?rculescu C, Venkataraman S, Languille B, Yu H, Tresset G. On-chip controlled surfactant-DNA coil-globule transition by rapid solvent exchange using hydrodynamic flow focusing. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 13125-36. PMID 25351469 DOI: 10.1021/la5035382  0.36
2014 Yin L, Zheng D, Limmon GV, Leung NH, Xu S, Rajapakse JC, Yu H, Chow VT, Chen J. Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia. Respiratory Research. 15: 116. PMID 25265939 DOI: 10.1186/s12931-014-0116-z  0.68
2014 Wang J, Tucker-Kellogg L, Ng IC, Jia R, Thiagarajan PS, White JK, Yu H. The self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation. Plos Computational Biology. 10: e1003573. PMID 24901250 DOI: 10.1371/journal.pcbi.1003573  0.84
2014 Cha JW, Singh VR, Kim KH, Subramanian J, Peng Q, Yu H, Nedivi E, So PT. Reassignment of scattered emission photons in multifocal multiphoton microscopy. Scientific Reports. 4: 5153. PMID 24898470 DOI: 10.1038/srep05153  0.44
2014 Ananthanarayanan A, Nugraha B, Triyatni M, Hart S, Sankuratri S, Yu H. Scalable spheroid model of human hepatocytes for hepatitis C infection and replication. Molecular Pharmaceutics. 11: 2106-14. PMID 24761996 DOI: 10.1021/mp500063y  0.44
2014 Stanciu SG, Xu S, Peng Q, Yan J, Stanciu GA, Welsch RE, So PT, Csucs G, Yu H. Experimenting liver fibrosis diagnostic by two photon excitation microscopy and Bag-of-Features image classification. Scientific Reports. 4: 4636. PMID 24717650 DOI: 10.1038/srep04636  0.88
2014 Xu S, Wang Y, Tai DC, Wang S, Cheng CL, Peng Q, Yan J, Chen Y, Sun J, Liang X, Zhu Y, Rajapakse JC, Welsch RE, So PT, Wee A, ... ... Yu H, et al. qFibrosis: a fully-quantitative innovative method incorporating histological features to facilitate accurate fibrosis scoring in animal model and chronic hepatitis B patients. Journal of Hepatology. 61: 260-9. PMID 24583249 DOI: 10.1016/j.jhep.2014.02.015  0.88
2014 Poenar DP, Iliescu C, Boulaire J, Yu H. Label-free virus identification and characterization using electrochemical impedance spectroscopy. Electrophoresis. 35: 433-40. PMID 24285469 DOI: 10.1002/elps.201300368  0.36
2014 Venkatesh SK, Xu S, Tai D, Yu H, Wee A. Correlation of MR elastography with morphometric quantification of liver fibrosis (Fibro-C-Index) in chronic hepatitis B. Magnetic Resonance in Medicine. 72: 1123-9. PMID 24166665 DOI: 10.1002/mrm.25002  0.68
2013 Anene-Nzelu CG, Peh KY, Fraiszudeen A, Kuan YH, Ng SH, Toh YC, Leo HL, Yu H. Scalable alignment of three-dimensional cellular constructs in a microfluidic chip. Lab On a Chip. 13: 4124-33. PMID 23969512 DOI: 10.1039/c3lc50730k  0.88
2013 Zheng D, Limmon GV, Yin L, Leung NH, Yu H, Chow VT, Chen J. A cellular pathway involved in Clara cell to alveolar type II cell differentiation after severe lung injury. Plos One. 8: e71028. PMID 23940685 DOI: 10.1371/journal.pone.0071028  0.88
2013 Parks Saldutti L, Beyer BK, Breslin W, Brown TR, Chapin RE, Campion S, Enright B, Faustman E, Foster PM, Hartung T, Kelce W, Kim JH, Loboa EG, Piersma AH, Seyler D, ... ... Yu H, et al. In vitro testicular toxicity models: opportunities for advancement via biomedical engineering techniques. Altex. 30: 353-77. PMID 23861079  0.88
2013 Anene-Nzelu CG, Choudhury D, Li H, Fraiszudeen A, Peh KY, Toh YC, Ng SH, Leo HL, Yu H. Scalable cell alignment on optical media substrates. Biomaterials. 34: 5078-87. PMID 23601659 DOI: 10.1016/j.biomaterials.2013.03.070  0.88
2013 Yin L, Xu S, Cheng J, Zheng D, Limmon GV, Leung NH, Rajapakse JC, Chow VT, Chen J, Yu H. Spatiotemporal quantification of cell dynamics in the lung following influenza virus infection. Journal of Biomedical Optics. 18: 046001. PMID 23545853 DOI: 10.1117/1.JBO.18.4.046001  0.88
2013 Narmada BC, Kang Y, Venkatraman L, Peng Q, Sakban RB, Nugraha B, Jiang X, Bunte RM, So PT, Tucker-Kellogg L, Mao HQ, Yu H. Hepatic stellate cell-targeted delivery of hepatocyte growth factor transgene via bile duct infusion enhances its expression at fibrotic foci to regress dimethylnitrosamine-induced liver fibrosis. Human Gene Therapy. 24: 508-19. PMID 23527815 DOI: 10.1089/hum.2012.158  0.84
2013 Li Y, Ho D, Meng H, Chan TR, An B, Yu H, Brodsky B, Jun AS, Michael Yu S. Direct detection of collagenous proteins by fluorescently labeled collagen mimetic peptides. Bioconjugate Chemistry. 24: 9-16. PMID 23253177 DOI: 10.1021/bc3005842  0.88
2013 Wang Y, Toh YC, Li Q, Nugraha B, Zheng B, Lu TB, Gao Y, Ng MM, Yu H. Mechanical compaction directly modulates the dynamics of bile canaliculi formation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 390-401. PMID 23233209 DOI: 10.1039/c2ib20229h  0.96
2013 Narmada BC, Chia SM, Tucker-Kellogg L, Yu H. HGF regulates the activation of TGF-β1 in rat hepatocytes and hepatic stellate cells. Journal of Cellular Physiology. 228: 393-401. PMID 22718393 DOI: 10.1002/jcp.24143  0.8
2012 Zheng D, Limmon GV, Yin L, Leung NH, Yu H, Chow VT, Chen J. Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza. Plos One. 7: e48451. PMID 23119022 DOI: 10.1371/journal.pone.0048451  0.88
2012 Venkatraman L, Chia SM, Narmada BC, White JK, Bhowmick SS, Forbes Dewey C, So PT, Tucker-Kellogg L, Yu H. Plasmin triggers a switch-like decrease in thrombospondin-dependent activation of TGF-β1. Biophysical Journal. 103: 1060-8. PMID 23009856 DOI: 10.1016/j.bpj.2012.06.050  0.88
2012 Wang X, Magalhães R, Wu Y, Wen F, Gouk SS, Watson PF, Yu H, Kuleshova LL. Development of a modified vitrification strategy suitable for subsequent scale-up for hepatocyte preservation. Cryobiology. 65: 289-300. PMID 22940432 DOI: 10.1016/j.cryobiol.2012.07.080  0.88
2012 Xia L, Arooz T, Zhang S, Tuo X, Xiao G, Susanto TA, Sundararajan J, Cheng T, Kang Y, Poh HJ, Leo HL, Yu H. Hepatocyte function within a stacked double sandwich culture plate cylindrical bioreactor for bioartificial liver system. Biomaterials. 33: 7925-32. PMID 22889484 DOI: 10.1016/j.biomaterials.2012.06.078  0.88
2012 Seah BS, Bhowmick SS, Dewey CF, Yu H. FUSE: a profit maximization approach for functional summarization of biological networks. Bmc Bioinformatics. 13: S10. PMID 22536894 DOI: 10.1186/1471-2105-13-S3-S10  0.52
2012 Huang T, Wang J, Cai YD, Yu H, Chou KC. Hepatitis C virus network based classification of hepatocellular cirrhosis and carcinoma. Plos One. 7: e34460. PMID 22493692 DOI: 10.1371/journal.pone.0034460  0.88
2012 Xia L, Sakban RB, Qu Y, Hong X, Zhang W, Nugraha B, Tong WH, Ananthanarayanan A, Zheng B, Chau IY, Jia R, McMillian M, Silva J, Dallas S, Yu H. Tethered spheroids as an in vitro hepatocyte model for drug safety screening. Biomaterials. 33: 2165-76. PMID 22189144 DOI: 10.1016/j.biomaterials.2011.12.006  0.88
2012 Choudhury D, van Noort D, Iliescu C, Zheng B, Poon KL, Korzh S, Korzh V, Yu H. Fish and Chips: a microfluidic perfusion platform for monitoring zebrafish development. Lab On a Chip. 12: 892-900. PMID 22146879 DOI: 10.1039/c1lc20351g  0.52
2012 Magalhães R, Nugraha B, Pervaiz S, Yu H, Kuleshova LL. Influence of cell culture configuration on the post-cryopreservation viability of primary rat hepatocytes. Biomaterials. 33: 829-36. PMID 22079007 DOI: 10.1016/j.biomaterials.2011.10.015  0.6
2011 Xu S, Tai D, Wee A, Welsch R, So P, Yu H, Rajapakse J. Automated scoring of liver fibrosis through combined features from different collagen groups. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 4503-6. PMID 22255339 DOI: 10.1109/IEMBS.2011.6091116  0.88
2011 Margadant F, Chew LL, Hu X, Yu H, Bate N, Zhang X, Sheetz M. Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin. Plos Biology. 9: e1001223. PMID 22205879 DOI: 10.1371/journal.pbio.1001223  0.88
2011 Lin J, Lu F, Zheng W, Xu S, Tai D, Yu H, Huang Z. Assessment of liver steatosis and fibrosis in rats using integrated coherent anti-Stokes Raman scattering and multiphoton imaging technique. Journal of Biomedical Optics. 16: 116024. PMID 22112129 DOI: 10.1117/1.3655353  0.56
2011 Zheng B, Tan L, Mo X, Yu W, Wang Y, Tucker-Kellogg L, Welsch RE, So PT, Yu H. Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis. Plos One. 6: e26230. PMID 22073152 DOI: 10.1371/journal.pone.0026230  0.88
2011 Toh YC, Blagovic K, Yu H, Voldman J. Spatially organized in vitro models instruct asymmetric stem cell differentiation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 1179-87. PMID 22028041 DOI: 10.1039/c1ib00113b  0.88
2011 Venkatraman L, Li H, Dewey CF, White JK, Bhowmick SS, Yu H, Tucker-Kellogg L. Steady states and dynamics of urokinase-mediated plasmin activation in silico and in vitro. Biophysical Journal. 101: 1825-34. PMID 22004735 DOI: 10.1016/j.bpj.2011.08.054  0.84
2011 Choudhury D, Mo X, Iliescu C, Tan LL, Tong WH, Yu H. Exploitation of physical and chemical constraints for three-dimensional microtissue construction in microfluidics. Biomicrofluidics. 5: 22203. PMID 21799710 DOI: 10.1063/1.3593407  0.6
2011 Nugraha B, Hong X, Mo X, Tan L, Zhang W, Chan PM, Kang CH, Wang Y, Beng LT, Sun W, Choudhury D, Robens JM, McMillian M, Silva J, Dallas S, ... ... Yu H, et al. Galactosylated cellulosic sponge for multi-well drug safety testing. Biomaterials. 32: 6982-94. PMID 21741702 DOI: 10.1016/j.biomaterials.2011.05.087  0.88
2011 Zhou J, Bi C, Chng WJ, Cheong LL, Liu SC, Mahara S, Tay KG, Zeng Q, Li J, Guo K, Tan CP, Yu H, Albert DH, Chen CS. PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapy. Plos One. 6: e19798. PMID 21589872 DOI: 10.1371/journal.pone.0019798  0.76
2011 Ananthanarayanan A, Narmada BC, Mo X, McMillian M, Yu H. Purpose-driven biomaterials research in liver-tissue engineering. Trends in Biotechnology. 29: 110-8. PMID 21129798 DOI: 10.1016/j.tibtech.2010.10.006  0.88
2011 Zhang S, Tong W, Zheng B, Susanto TA, Xia L, Zhang C, Ananthanarayanan A, Tuo X, Sakban RB, Jia R, Iliescu C, Chai KH, McMillian M, Shen S, Leo H, ... Yu H, et al. A robust high-throughput sandwich cell-based drug screening platform. Biomaterials. 32: 1229-41. PMID 20971505 DOI: 10.1016/j.biomaterials.2010.09.064  0.88
2010 Wang Y, Susando T, Lei X, Anene-Nzelu C, Zhou H, Liang LH, Yu H. Current development of bioreactors for extracorporeal bioartificial liver (Review). Biointerphases. 5: FA116-31. PMID 21171705 DOI: 10.1116/1.3521520  0.96
2010 Raja AM, Xu S, Sun W, Zhou J, Tai DC, Chen CS, Rajapakse JC, So PT, Yu H. Pulse-modulated second harmonic imaging microscope quantitatively demonstrates marked increase of collagen in tumor after chemotherapy. Journal of Biomedical Optics. 15: 056016. PMID 21054110 DOI: 10.1117/1.3497565  0.72
2010 He Y, Kang CH, Xu S, Tuo X, Trasti S, Tai DC, Raja AM, Peng Q, So PT, Rajapakse JC, Welsch R, Yu H. Toward surface quantification of liver fibrosis progression. Journal of Biomedical Optics. 15: 056007. PMID 21054101 DOI: 10.1117/1.3490414  0.88
2010 Zhang X, Tee YH, Heng JK, Zhu Y, Hu X, Margadant F, Ballestrem C, Bershadsky A, Griffiths G, Yu H. Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella. Journal of Cell Science. 123: 3901-12. PMID 20980389 DOI: 10.1242/jcs.069153  0.88
2010 Yue Z, Wen F, Gao S, Ang MY, Pallathadka PK, Liu L, Yu H. Preparation of three-dimensional interconnected macroporous cellulosic hydrogels for soft tissue engineering. Biomaterials. 31: 8141-52. PMID 20691470 DOI: 10.1016/j.biomaterials.2010.07.059  0.88
2010 Mo X, Li Q, Yi Lui LW, Zheng B, Kang CH, Nugraha B, Yue Z, Jia RR, Fu HX, Choudhury D, Arooz T, Yan J, Lim CT, Shen S, Hong Tan C, ... Yu H, et al. Rapid construction of mechanically- confined multi- cellular structures using dendrimeric intercellular linker. Biomaterials. 31: 7455-67. PMID 20599265 DOI: 10.1016/j.biomaterials.2010.06.020  0.6
2010 Zhang W, Tucker-Kellogg L, Narmada BC, Venkatraman L, Chang S, Lu Y, Tan N, White JK, Jia R, Bhowmick SS, Shen S, Dewey CF, Yu H. Cell-delivery therapeutics for liver regeneration. Advanced Drug Delivery Reviews. 62: 814-26. PMID 20193722 DOI: 10.1016/j.addr.2010.02.005  0.72
2010 Venkatraman L, Yu H, Bhowmick SS, Dewey F, Tucker-Kellogg L. The steady states and dynamics of urokinase-mediated plasmin activation. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 190-200. PMID 19908371  0.72
2010 Ong SM, Zhao Z, Arooz T, Zhao D, Zhang S, Du T, Wasser M, van Noort D, Yu H. Engineering a scaffold-free 3D tumor model for in vitro drug penetration studies. Biomaterials. 31: 1180-90. PMID 19889455 DOI: 10.1016/j.biomaterials.2009.10.049  0.52
2009 Ni M, Tong WH, Choudhury D, Rahim NA, Iliescu C, Yu H. Cell culture on MEMS platforms: a review. International Journal of Molecular Sciences. 10: 5411-41. PMID 20054478 DOI: 10.3390/ijms10125411  0.68
2009 Zhang C, Zhao Z, Abdul Rahim NA, van Noort D, Yu H. Towards a human-on-chip: culturing multiple cell types on a chip with compartmentalized microenvironments. Lab On a Chip. 9: 3185-92. PMID 19865724 DOI: 10.1039/b915147h  0.52
2009 Tai DC, Tan N, Xu S, Kang CH, Chia SM, Cheng CL, Wee A, Wei CL, Raja AM, Xiao G, Chang S, Rajapakse JC, So PT, Tang HH, Chen CS, ... Yu H, et al. Fibro-C-Index: comprehensive, morphology-based quantification of liver fibrosis using second harmonic generation and two-photon microscopy. Journal of Biomedical Optics. 14: 044013. PMID 19725725 DOI: 10.1117/1.3183811  0.8
2009 Xia L, Ng S, Han R, Tuo X, Xiao G, Leo HL, Cheng T, Yu H. Laminar-flow immediate-overlay hepatocyte sandwich perfusion system for drug hepatotoxicity testing. Biomaterials. 30: 5927-36. PMID 19646750 DOI: 10.1016/j.biomaterials.2009.07.022  0.88
2009 Toh YC, Lim TC, Tai D, Xiao G, van Noort D, Yu H. A microfluidic 3D hepatocyte chip for drug toxicity testing. Lab On a Chip. 9: 2026-35. PMID 19568671 DOI: 10.1039/b900912d  0.88
2009 Magalhães R, Anil Kumar PR, Wen F, Zhao X, Yu H, Kuleshova LL. The use of vitrification to preserve primary rat hepatocyte monolayer on collagen-coated poly(ethylene-terephthalate) surfaces for a hybrid liver support system. Biomaterials. 30: 4136-42. PMID 19477507 DOI: 10.1016/j.biomaterials.2009.04.037  0.88
2009 Pan X, Shi X, Korzh V, Yu H, Wohland T. Line scan fluorescence correlation spectroscopy for three-dimensional microfluidic flow velocity measurements. Journal of Biomedical Optics. 14: 024049. PMID 19405777 DOI: 10.1117/1.3094947  0.88
2009 Zhang C, Chia SM, Ong SM, Zhang S, Toh YC, van Noort D, Yu H. The controlled presentation of TGF-beta1 to hepatocytes in a 3D-microfluidic cell culture system. Biomaterials. 30: 3847-53. PMID 19394078 DOI: 10.1016/j.biomaterials.2009.03.052  0.88
2009 van Noort D, Ong SM, Zhang C, Zhang S, Arooz T, Yu H. Stem cells in microfluidics. Biotechnology Progress. 25: 52-60. PMID 19205022 DOI: 10.1002/btpr.171  0.52
2009 Zhou J, Bi C, Janakakumara JV, Liu SC, Chng WJ, Tay KG, Poon LF, Xie Z, Palaniyandi S, Yu H, Glaser KB, Albert DH, Davidsen SK, Chen CS. Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML. Blood. 113: 4052-62. PMID 19144991 DOI: 10.1182/blood-2008-05-156422  0.64
2009 Liu P, Zhang YW, Yu H, Zhang X, Cheng QH, Lu C, Bonfield W. Spreading of an anchorage-dependent cell on a selectively ligand-coated substrate mediated by receptor-ligand binding. Journal of Biomedical Materials Research. Part A. 91: 806-13. PMID 19051302 DOI: 10.1002/jbm.a.32258  0.56
2008 Sun W, Chang S, Tai DC, Tan N, Xiao G, Tang H, Yu H. Nonlinear optical microscopy: use of second harmonic generation and two-photon microscopy for automated quantitative liver fibrosis studies. Journal of Biomedical Optics. 13: 064010. PMID 19123657 DOI: 10.1117/1.3041159  0.72
2008 Zhang S, Xia L, Kang CH, Xiao G, Ong SM, Toh YC, Leo HL, van Noort D, Kan SH, Tang HH, Yu H. Microfabricated silicon nitride membranes for hepatocyte sandwich culture. Biomaterials. 29: 3993-4002. PMID 18635259 DOI: 10.1016/j.biomaterials.2008.06.024  0.88
2008 Zhao D, Ong SM, Yue Z, Jiang Z, Toh YC, Khan M, Shi J, Tan CH, Chen JP, Yu H. Dendrimer hydrazides as multivalent transient inter-cellular linkers. Biomaterials. 29: 3693-702. PMID 18554713 DOI: 10.1016/j.biomaterials.2008.05.019  0.88
2008 Ong SM, Zhang C, Toh YC, Kim SH, Foo HL, Tan CH, van Noort D, Park S, Yu H. A gel-free 3D microfluidic cell culture system. Biomaterials. 29: 3237-44. PMID 18455231 DOI: 10.1016/j.biomaterials.2008.04.022  0.88
2008 Toh YC, Zhang J, Khong YM, Du Y, Sun W, Yu H. Integrating sensitive quantification of hepatic metabolic functions by capillary electrophoresis with laser-induced fluorescence detection. The Analyst. 133: 326-30. PMID 18299746 DOI: 10.1039/b716420c  0.88
2008 Zhou J, Khng J, Jasinghe VJ, Bi C, Neo CH, Pan M, Poon LF, Xie Z, Yu H, Yeoh AE, Lu Y, Glaser KB, Albert DH, Davidsen SK, Chen CS. In vivo activity of ABT-869, a multi-target kinase inhibitor, against acute myeloid leukemia with wild-type FLT3 receptor. Leukemia Research. 32: 1091-100. PMID 18160102 DOI: 10.1016/j.leukres.2007.11.025  0.64
2008 Du Y, Han R, Wen F, Ng San San S, Xia L, Wohland T, Leo HL, Yu H. Synthetic sandwich culture of 3D hepatocyte monolayer. Biomaterials. 29: 290-301. PMID 17964646 DOI: 10.1016/j.biomaterials.2007.09.016  0.88
2007 Khong YM, Zhang J, Zhou S, Cheung C, Doberstein K, Samper V, Yu H. Novel intra-tissue perfusion system for culturing thick liver tissue. Tissue Engineering. 13: 2345-56. PMID 17708717 DOI: 10.1089/ten.2007.0040  0.76
2007 Pan X, Foo W, Lim W, Fok MH, Liu P, Yu H, Maruyama I, Wohland T. Multifunctional fluorescence correlation microscope for intracellular and microfluidic measurements. The Review of Scientific Instruments. 78: 053711. PMID 17552829 DOI: 10.1063/1.2740053  0.88
2007 Kim L, Toh YC, Voldman J, Yu H. A practical guide to microfluidic perfusion culture of adherent mammalian cells. Lab On a Chip. 7: 681-94. PMID 17538709 DOI: 10.1039/b704602b  0.88
2007 Du Y, Han R, Ng S, Ni J, Sun W, Wohland T, Ong SH, Kuleshova L, Yu H. Identification and characterization of a novel prespheroid 3-dimensional hepatocyte monolayer on galactosylated substratum. Tissue Engineering. 13: 1455-68. PMID 17518743 DOI: 10.1089/ten.2006.0381  0.88
2007 Schumacher K, Khong YM, Chang S, Ni J, Sun W, Yu H. Perfusion culture improves the maintenance of cultured liver tissue slices. Tissue Engineering. 13: 197-205. PMID 17518593 DOI: 10.1089/ten.2006.0046  0.72
2007 Ong SM, He L, Thuy Linh NT, Tee YH, Arooz T, Tang G, Tan CH, Yu H. Transient inter-cellular polymeric linker. Biomaterials. 28: 3656-67. PMID 17512584 DOI: 10.1016/j.biomaterials.2007.04.034  0.88
2007 Wu Y, Yu H, Chang S, Magalhães R, Kuleshova LL. Vitreous cryopreservation of cell-biomaterial constructs involving encapsulated hepatocytes. Tissue Engineering. 13: 649-58. PMID 17362134 DOI: 10.1089/ten.2006.0075  0.6
2007 Pan X, Yu H, Shi X, Korzh V, Wohland T. Characterization of flow direction in microchannels and zebrafish blood vessels by scanning fluorescence correlation spectroscopy. Journal of Biomedical Optics. 12: 014034. PMID 17343509 DOI: 10.1117/1.2435173  0.88
2007 Toh YC, Zhang C, Zhang J, Khong YM, Chang S, Samper VD, van Noort D, Hutmacher DW, Yu H. A novel 3D mammalian cell perfusion-culture system in microfluidic channels. Lab On a Chip. 7: 302-9. PMID 17330160 DOI: 10.1039/b614872g  0.88
2006 Zhu J, Zhang B, Yan X, Lao X, Yu H. [Encapsulating hepatocytes with chitosan in physiological conditions]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi. 23: 1070-4. PMID 17121357  0.64
2006 Ng S, Han R, Chang S, Ni J, Hunziker W, Goryachev AB, Ong SH, Yu H. Improved hepatocyte excretory function by immediate presentation of polarity cues. Tissue Engineering. 12: 2181-91. PMID 16968159 DOI: 10.1089/ten.2006.12.2181  0.88
2006 Ong LL, Lin PC, Zhang X, Chia SM, Yu H. Kinectin-dependent assembly of translation elongation factor-1 complex on endoplasmic reticulum regulates protein synthesis. The Journal of Biological Chemistry. 281: 33621-34. PMID 16950774 DOI: 10.1074/jbc.M607555200  0.8
2006 Du Y, Chia SM, Han R, Chang S, Tang H, Yu H. 3D hepatocyte monolayer on hybrid RGD/galactose substratum. Biomaterials. 27: 5669-80. PMID 16904177 DOI: 10.1016/j.biomaterials.2006.07.018  0.88
2005 Lu HF, Lim WS, Zhang PC, Chia SM, Yu H, Mao HQ, Leong KW. Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture. Tissue Engineering. 11: 1667-77. PMID 16411812 DOI: 10.1089/ten.2005.11.1667  0.84
2005 Lin PC, Cheng PC, Yu H. An engineered microenvironment for multidimensional microscopy of live cells. Scanning. 27: 284-92. PMID 16370396  0.64
2005 Chia SM, Lin PC, Quek CH, Yin C, Mao HQ, Leong KW, Xu X, Goh CH, Ng ML, Yu H. Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells. Journal of Biotechnology. 118: 434-47. PMID 16026880 DOI: 10.1016/j.jbiotec.2005.05.012  0.84
2005 Zhu JH, Wang XW, Ng S, Quek CH, Ho HT, Lao XJ, Yu H. Encapsulating live cells with water-soluble chitosan in physiological conditions. Journal of Biotechnology. 117: 355-65. PMID 15925718 DOI: 10.1016/j.jbiotec.2005.03.011  0.76
2005 Zhu JH, Zhang B, Fang WW, Lao XJ, Yu H. Characterization of amphoteric multilayered thin films by means of zeta potential measurements. Colloids and Surfaces. B, Biointerfaces. 43: 1-6. PMID 15885992 DOI: 10.1016/j.colsurfb.2005.03.010  0.72
2005 Toh YC, Ng S, Khong YM, Samper V, Yu H. A configurable three-dimensional microenvironment in a microfluidic channel for primary hepatocyte culture. Assay and Drug Development Technologies. 3: 169-76. PMID 15871691 DOI: 10.1089/adt.2005.3.169  0.88
2005 Zhou Y, Sun T, Chan M, Zhang J, Han Z, Wang X, Toh Y, Chen JP, Yu H. Scalable encapsulation of hepatocytes by electrostatic spraying. Journal of Biotechnology. 117: 99-109. PMID 15831251 DOI: 10.1016/j.jbiotec.2004.11.004  0.76
2005 Chia SM, Lin PC, Yu H. TGF-beta1 regulation in hepatocyte-NIH3T3 co-culture is important for the enhanced hepatocyte function in 3D microenvironment. Biotechnology and Bioengineering. 89: 565-73. PMID 15669090 DOI: 10.1002/bit.20372  0.8
2005 Toh YC, Ho ST, Zhou Y, Hutmacher DW, Yu H. Application of a polyelectrolyte complex coacervation method to improve seeding efficiency of bone marrow stromal cells in a 3D culture system. Biomaterials. 26: 4149-60. PMID 15664642 DOI: 10.1016/j.biomaterials.2004.10.033  0.88
2005 Ng S, Wu YN, Zhou Y, Toh YE, Ho ZZ, Chia SM, Zhu JH, Mao HQ, Yu H. Optimization of 3-D hepatocyte culture by controlling the physical and chemical properties of the extra-cellular matrices. Biomaterials. 26: 3153-63. PMID 15603810 DOI: 10.1016/j.biomaterials.2004.08.017  0.84
2004 Zhang J, Wei HP, Quek CH, Chia SM, Yu H. Quantitative measurement of collagen methylation by capillary electrophoresis. Electrophoresis. 25: 3416-21. PMID 15490447 DOI: 10.1002/elps.200406071  0.88
2004 Santama N, Er CP, Ong LL, Yu H. Distribution and functions of kinectin isoforms. Journal of Cell Science. 117: 4537-49. PMID 15316074 DOI: 10.1242/jcs.01326  0.32
2004 Wang J, Lee IL, Lim WS, Chia SM, Yu H, Leong KW, Mao HQ. Evaluation of collagen and methylated collagen as gene carriers. International Journal of Pharmaceutics. 279: 115-26. PMID 15234800 DOI: 10.1016/j.ijpharm.2004.04.014  0.84
2004 Quek CH, Li J, Sun T, Chan ML, Mao HQ, Gan LM, Leong KW, Yu H. Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation. Biomaterials. 25: 3531-40. PMID 15020127 DOI: 10.1016/j.biomaterials.2003.09.112  0.84
2003 Lu HF, Lim WS, Wang J, Tang ZQ, Zhang PC, Leong KW, Chia SM, Yu H, Mao HQ. Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance. Biomaterials. 24: 4893-903. PMID 14559002  0.84
2003 Sun T, Chan ML, Zhou Y, Xu X, Zhang J, Lao X, Wang X, Quek CH, Chen JP, Leong KW, Yu H. Use of ultrathin shell microcapsules of hepatocytes in bioartificial liver-assist device. Tissue Engineering. 9: S65-75. PMID 14511471 DOI: 10.1089/10763270360696987  0.84
2003 Wong SC, Ong LL, Er CP, Gao S, Yu H, So JB. Cloning of rat telomerase catalytic subunit functional domains, reconstitution of telomerase activity and enzymatic profile of pig and chicken tissues. Life Sciences. 73: 2749-60. PMID 13679242  0.84
2003 Ong LL, Er CP, Ho A, Aung MT, Yu H. Kinectin anchors the translation elongation factor-1 delta to the endoplasmic reticulum. The Journal of Biological Chemistry. 278: 32115-23. PMID 12773547 DOI: 10.1074/jbc.M210917200  0.32
2003 Xu X, Yee WC, Hwang PY, Yu H, Wan AC, Gao S, Boon KL, Mao HQ, Leong KW, Wang S. Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. Biomaterials. 24: 2405-12. PMID 12699678  0.84
2003 Yin C, Mien Chia S, Hoon Quek C, Yu H, Zhuo RX, Leong KW, Mao HQ. Microcapsules with improved mechanical stability for hepatocyte culture. Biomaterials. 24: 1771-80. PMID 12593959  0.84
2002 Xu X, Yu H, Gao S, Ma HQ, Leong KW, Wang S. Polyphosphoester microspheres for sustained release of biologically active nerve growth factor. Biomaterials. 23: 3765-72. PMID 12109702  0.84
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