Kam W. Leong, Ph.D. - Publications

Affiliations: 
Biomedical Engineering Duke University, Durham, NC 
Area:
Biomaterials, Controlled Drug and Gene Delivery, Tissue Engineering
Website:
http://fds.duke.edu/db/pratt/BME/kam.leong

213 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yan H, Shao D, Lao YH, Li M, Hu H, Leong KW. Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1900605. PMID 31406672 DOI: 10.1002/advs.201900605  1
2019 Nie T, He Z, Zhou Y, Zhu J, Chen K, Liu L, Leong KW, Mao HQ, Chen Y. A Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1. Acs Applied Materials & Interfaces. PMID 31348859 DOI: 10.1021/acsami.9b10294  1
2019 Sheth RU, Li M, Jiang W, Sims PA, Leong KW, Wang HH. Spatial metagenomic characterization of microbial biogeography in the gut. Nature Biotechnology. PMID 31332325 DOI: 10.1038/s41587-019-0183-2  0.64
2019 Chin JS, Chooi WH, Wang H, Ong W, Leong KW, Chew SY. Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing. Acta Biomaterialia. PMID 30978509 DOI: 10.1016/j.actbio.2019.04.020  1
2019 He Z, Hu Y, Gui Z, Zhou Y, Nie T, Zhu J, Liu Z, Chen K, Liu L, Leong KW, Cao P, Chen Y, Mao HQ. Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30894322 DOI: 10.1016/j.jconrel.2019.03.014  1
2019 Suryaprakash S, Lao YH, Cho HY, Li M, Ji HY, Shao D, Hu H, Quek CH, Huang D, Mintz R, Bagó JR, Hingtgen S, Lee KB, Leong KW. Engineered MSC/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy. Nano Letters. PMID 30773888 DOI: 10.1021/acs.nanolett.8b04697  1
2019 Peng B, Liang H, Li Y, Dong C, Shen J, Mao HQ, Leong KW, Chen Y, Liu L. Tuned Cationic Dendronized Polymer as a Molecular Scavenger for Rheumatoid Arthritis Treatment. Angewandte Chemie (International Ed. in English). PMID 30724436 DOI: 10.1002/anie.201813362  1
2019 Li M, Lao YH, Mintz RL, Chen Z, Shao D, Hu H, Wang HX, Tao Y, Leong KW. A multifunctional mesoporous silica-gold nanocluster hybrid platform for selective breast cancer cell detection using a catalytic amplification-based colorimetric assay. Nanoscale. PMID 30694277 DOI: 10.1039/c8nr08337a  1
2018 Kim HS, Sun X, Lee JH, Kim HW, Fu X, Leong KW. Advanced drug delivery systems and artificial skin grafts for skin wound healing. Advanced Drug Delivery Reviews. PMID 30605737 DOI: 10.1016/j.addr.2018.12.014  1
2018 Sun L, Liu Z, Tian H, Le Z, Liu L, Leong KW, Mao HQ, Chen Y. Scalable Manufacturing of Enteric Encapsulation Systems for Site-Specific Oral Insulin Delivery. Biomacromolecules. PMID 30537806 DOI: 10.1021/acs.biomac.8b01530  1
2018 Le Z, Chen Y, Han H, Tian H, Zhao P, Yang C, He Z, Liu L, Leong KW, Mao HQ, Liu Z, Chen Y. Hydrogen-Bonded Tannic Acid-Based Anticancer Nanoparticle for Enhancement of Oral Chemotherapy. Acs Applied Materials & Interfaces. PMID 30444601 DOI: 10.1021/acsami.8b18979  1
2018 Zeng Z, Dong C, Zhao P, Liu Z, Liu L, Mao HQ, Leong KW, Gao X, Chen Y. Scalable Production of Therapeutic Protein Nanoparticles Using Flash Nanoprecipitation. Advanced Healthcare Materials. e1801010. PMID 30338666 DOI: 10.1002/adhm.201801010  1
2018 Liang H, Peng B, Dong C, Liu L, Mao J, Wei S, Wang X, Xu H, Shen J, Mao HQ, Gao X, Leong KW, Chen Y. Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation. Nature Communications. 9: 4291. PMID 30327464 DOI: 10.1038/s41467-018-06603-5  1
2018 He Z, Hu Y, Nie T, Tang H, Zhu J, Chen K, Liu L, Leong KW, Chen Y, Mao HQ. Size-Controlled Lipid Nanoparticle Production Using Turbulent Mixing to Enhance Oral DNA Delivery. Acta Biomaterialia. PMID 30267888 DOI: 10.1016/j.actbio.2018.09.047  1
2018 Lin PY, Chiu YL, Huang JH, Chuang EY, Mi FL, Lin KJ, Juang JH, Sung HW, Leong KW. Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 5: 1701079. PMID 30128227 DOI: 10.1002/advs.201701079  1
2018 He J, Sun C, Gu Z, Yang Y, Gu M, Xue C, Xie Z, Ren H, Wang Y, Liu Y, Liu M, Ding F, Leong KW, Gu X. Morphology, Migration and Transcriptome Analysis of Schwann Cell Culture on Butterfly Wings with Different Surface Architectures. Acs Nano. PMID 30125084 DOI: 10.1021/acsnano.8b00552  1
2018 Lao YH, Li M, Gao MA, Shao D, Chi CW, Huang D, Chakraborty S, Ho TC, Jiang W, Wang HX, Wang S, Leong KW. HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Argonaute. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 5: 1700540. PMID 30027026 DOI: 10.1002/advs.201700540  1
2018 Tian H, He Z, Sun C, Yang C, Zhao P, Liu L, Leong KW, Mao HQ, Liu Z, Chen Y. Uniform Core-Shell Nanoparticles with Thiolated Hyaluronic Acid Coating to Enhance Oral Delivery of Insulin. Advanced Healthcare Materials. e1800285. PMID 29984479 DOI: 10.1002/adhm.201800285  1
2018 Chan HF, Zhao R, Parada GA, Meng H, Leong KW, Griffith LG, Zhao X. Folding artificial mucosa with cell-laden hydrogels guided by mechanics models. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967135 DOI: 10.1073/pnas.1802361115  1
2018 Pinese C, Lin J, Milbreta U, Li M, Wang Y, Leong KW, Chew SY. Sustained delivery of siRNA/mesoporous silica nanoparticle (siRNA/MSN) complexes from nanofiber scaffolds for long-term gene silencing. Acta Biomaterialia. PMID 29890267 DOI: 10.1016/j.actbio.2018.05.054  1
2018 Shao D, Li M, Wang Z, Zheng X, Lao YH, Chang Z, Zhang F, Lu M, Yue J, Hu H, Yan H, Chen L, Dong WF, Leong KW. Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery. Advanced Materials (Deerfield Beach, Fla.). e1801198. PMID 29808576 DOI: 10.1002/adma.201801198  1
2018 Meng H, Leong W, Leong KW, Chen C, Zhao Y. Walking the line: The fate of nanomaterials at biological barriers. Biomaterials. 174: 41-53. PMID 29778981 DOI: 10.1016/j.biomaterials.2018.04.056  0.68
2018 Xue Q, Liu XB, Lao YH, Wu LP, Wang D, Zuo ZQ, Chen JY, Hou J, Bei YY, Wu XF, Leong KW, Xiang H, Han J. Anti-infective biomaterials with surface-decorated tachyplesin I. Biomaterials. PMID 29778319 DOI: 10.1016/j.biomaterials.2018.05.008  1
2018 Qiao D, Liu L, Chen Y, Xue C, Gao Q, Mao HQ, Leong KW, Chen Y. Potency of A Scalable Nanoparticulate Subunit Vaccine. Nano Letters. PMID 29694053 DOI: 10.1021/acs.nanolett.8b00478  1
2018 Zeng Y, Wong ST, Teo SK, Leong KW, Chiam KH, Yim EKF. Human mesenchymal stem cell basal membrane bending on gratings is dependent on both grating width and curvature. Scientific Reports. 8: 6444. PMID 29691432 DOI: 10.1038/s41598-018-24123-6  0.64
2018 Wang HX, Song Z, Lao YH, Xu X, Gong J, Cheng D, Chakraborty S, Park JS, Li M, Huang D, Yin L, Cheng J, Leong KW. Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686087 DOI: 10.1073/pnas.1712963115  1
2018 He Z, Liu Z, Tian H, Hu Y, Liu L, Leong KW, Mao HQ, Chen Y. Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin. Nanoscale. PMID 29384554 DOI: 10.1039/c7nr08047f  1
2017 Peng B, Lai X, Chen L, Lin X, Sun C, Liu L, Qi S, Chen Y, Leong KW. Scarless Wound Closure by a Mussel-Inspired Poly(amidoamine) Tissue Adhesive with Tunable Degradability. Acs Omega. 2: 6053-6062. PMID 30023761 DOI: 10.1021/acsomega.7b01221  1
2017 Charoensook SN, Williams DJ, Chakraborty S, Leong KW, Vunjak-Novakovic G. Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 29168874 DOI: 10.1039/c7ib00144d  1
2017 Charoensook SN, Williams DJ, Chakraborty S, Leong KW, Vunjak-Novakovic G. Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 29168874 DOI: 10.1039/c7ib00144d  1
2017 Ji H, Kim HS, Kim HW, Leong KW. Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases. Current Opinion in Biomedical Engineering. 1: 38-44. PMID 29082353 DOI: 10.1016/j.cobme.2017.02.005  1
2017 Yang Y, Wang K, Gu X, Leong KW. Biophysical Regulation of Cell Behavior-Cross Talk between Substrate Stiffness and Nanotopography. Engineering (Beijing, China). 3: 36-54. PMID 29071164 DOI: 10.1016/J.ENG.2017.01.014  1
2017 Kim JW, Mahapatra C, Hong JY, Kim MS, Leong KW, Kim HW, Hyun JK. Functional Recovery of Contused Spinal Cord in Rat with the Injection of Optimal-Dosed Cerium Oxide Nanoparticles. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 4: 1700034. PMID 29051850 DOI: 10.1002/advs.201700034  1
2017 Zhang J, Zheng Y, Xie X, Wang L, Su Z, Wang Y, Leong KW, Chen M. Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy. Molecular Pharmaceutics. PMID 28994600 DOI: 10.1021/acs.molpharmaceut.7b00404  1
2017 Wang HX, Li M, Lee CM, Chakraborty S, Kim HW, Bao G, Leong KW. CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery. Chemical Reviews. PMID 28640612 DOI: 10.1021/acs.chemrev.6b00799  1
2017 Zhang J, Li J, Shi Z, Yang Y, Xie X, Lee SM, Wang Y, Leong KW, Chen M. pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities. Acta Biomaterialia. PMID 28455219 DOI: 10.1016/j.actbio.2017.04.029  1
2017 He Z, Santos JL, Tian H, Huang H, Hu Y, Liu L, Leong KW, Chen Y, Mao HQ. Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin. Biomaterials. 130: 28-41. PMID 28359018 DOI: 10.1016/j.biomaterials.2017.03.028  1
2017 Pelaz B, Alexiou C, Alvarez-Puebla RA, Alves F, Andrews AM, Ashraf S, Balogh LP, Ballerini L, Bestetti A, Brendel C, Bosi S, Carril M, Chan WC, Chen C, Chen X, ... ... Leong KW, et al. Diverse Applications of Nanomedicine. Acs Nano. PMID 28290206 DOI: 10.1021/acsnano.6b06040  1
2017 Singh RK, Patel KD, Leong KW, Kim HW. Progress in Nanotheranostics Based on Mesoporous Silica Nanomaterial Platforms. Acs Applied Materials & Interfaces. PMID 28274115 DOI: 10.1021/acsami.6b16505  1
2017 Li M, Jiang W, Chen Z, Suryaprakash S, Lv S, Tang Z, Chen X, Leong KW. A versatile platform for surface modification of microfluidic droplets. Lab On a Chip. PMID 28154857 DOI: 10.1039/c7lc00079k  1
2017 Christoforou N, Chakraborty S, Kirkton RD, Adler AF, Addis RC, Leong KW. Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage. Scientific Reports. 7: 40285. PMID 28071742 DOI: 10.1038/srep40285  1
2016 Lu M, Ozcelik A, Grigsby CL, Zhao Y, Guo F, Leong KW, Huang TJ. Microfluidic Hydrodynamic Focusing for Synthesis of Nanomaterials. Nano Today. 11: 778-792. PMID 30337950 DOI: 10.1016/j.nantod.2016.10.006  1
2016 Wang K, Leong KW, Yang Y. Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior. Journal of Visualized Experiments : Jove. PMID 28060299 DOI: 10.3791/54840  1
2016 Jiang W, Li M, Chen Z, Leong KW. Cell-laden microfluidic microgels for tissue regeneration. Lab On a Chip. PMID 27797383 DOI: 10.1039/c6lc01193d  1
2016 Jackman JG, Juwarker H, Poveromo LP, Levinson H, Leong KW, Sullenger BA. Polycationic Nanofibers for Nucleic Acid Scavenging. Biomacromolecules. PMID 27741396 DOI: 10.1021/acs.biomac.6b01236  1
2016 Black JB, Adler AF, Wang HG, D'Ippolito AM, Hutchinson HA, Reddy TE, Pitt GS, Leong KW, Gersbach CA. Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. Cell Stem Cell. PMID 27524438 DOI: 10.1016/j.stem.2016.07.001  1
2016 Zhao X, Yang K, Zhao R, Ji T, Wang X, Yang X, Zhang Y, Cheng K, Liu S, Hao J, Ren H, Leong KW, Nie G. Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy. Biomaterials. 102: 187-197. PMID 27343466 DOI: 10.1016/j.biomaterials.2016.06.032  1
2016 Lao YH, Chi CW, Friedrich SM, Peck K, Wang TH, Leong KW, Chen LC. Signal-On Protein Detection via Dye Translocation between Aptamer and Quantum Dot. Acs Applied Materials & Interfaces. PMID 27101438 DOI: 10.1021/acsami.6b02871  1
2016 Wang S, Xu Y, Chan HF, Kim HW, Wang Y, Leong KW, Chen M. phicaNanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27091696 DOI: 10.1016/j.jconrel.2016.04.018  1
2016 Chan HF, Ma S, Leong KW. Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies? Regenerative Biomaterials. 3: 87-98. PMID 27047674 DOI: 10.1093/rb/rbw009  1
2016 Peters EB, Christoforou N, Leong KW, Truskey GA, West JL. Poly(ethylene glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells. Cellular and Molecular Bioengineering. 9: 38-54. PMID 27042236 DOI: 10.1007/s12195-015-0423-6  1
2016 Chan HF, Zhang Y, Leong KW. Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions. Small (Weinheim An Der Bergstrasse, Germany). PMID 27038291 DOI: 10.1002/smll.201502932  1
2016 Kim TH, Kim SH, Leong KW, Jung Y. Nanografted Substrata and Tri-Culture of Human Pericytes, Fibroblasts, and Endothelial Cells for Studying the Effects on Angiogenesis. Tissue Engineering. Part A. PMID 27019156 DOI: 10.1089/ten.TEA.2015.0461  1
2016 Huang S, Lee AJ, Tsoi R, Wu F, Zhang Y, Leong KW, You L. Coupling spatial segregation with synthetic circuits to control bacterial survival. Molecular Systems Biology. 12: 859. PMID 26925805  1
2016 Ji H, Atchison L, Chen Z, Chakraborty S, Jung Y, Truskey GA, Christoforou N, Leong KW. Transdifferentiation of human endothelial progenitors into smooth muscle cells. Biomaterials. 85: 180-194. PMID 26874281 DOI: 10.1016/j.biomaterials.2016.01.066  1
2016 Peters EB, Christoforou N, Leong KW, Truskey GA, West JL. Poly(Ethylene Glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells Cellular and Molecular Bioengineering. 9: 38-54. DOI: 10.1007/s12195-015-0423-6  1
2015 Phua KK, Staats HF, Nair SK, Leong KW. Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 213: e66-7. PMID 27005208 DOI: 10.1016/j.jconrel.2015.05.110  1
2015 Zhang Y, Phua K, Chan HF, Sullenger B, Leong KW. Immobilization of nucleic acid binding polymers as anti-inflammatory agent in autoimmunity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 213: e136. PMID 27005091 DOI: 10.1016/j.jconrel.2015.05.230  1
2015 Lorden ER, Miller KJ, Ibrahim MM, Bashirov L, Hammett E, Chakraborty S, Quiles-Torres C, Selim MA, Leong KW, Levinson H. Biostable electrospun microfibrous scaffolds mitigate hypertrophic scar contraction in an immune-competent murine model. Acta Biomaterialia. PMID 26708709 DOI: 10.1016/j.actbio.2015.12.025  1
2015 Jung Y, Ji H, Chen Z, Fai Chan H, Atchison L, Klitzman B, Truskey G, Leong KW. Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. Scientific Reports. 5: 15116. PMID 26456074 DOI: 10.1038/srep15116  1
2015 Baek S, Singh RK, Khanal D, Patel KD, Lee EJ, Leong KW, Chrzanowski W, Kim HW. Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles. Nanoscale. 7: 14191-216. PMID 26260245 DOI: 10.1039/c5nr02730f  1
2015 Hong S, Sycks D, Chan HF, Lin S, Lopez GP, Guilak F, Leong KW, Zhao X. 3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. Advanced Materials (Deerfield Beach, Fla.). 27: 4034. PMID 26172844 DOI: 10.1002/adma.201570182  1
2015 Hong S, Sycks D, Chan HF, Lin S, Lopez GP, Guilak F, Leong KW, Zhao X. 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. Advanced Materials (Deerfield Beach, Fla.). 27: 4035-40. PMID 26033288 DOI: 10.1002/adma.201501099  1
2015 Peng B, Chen Y, Leong KW. MicroRNA delivery for regenerative medicine. Advanced Drug Delivery Reviews. 88: 108-22. PMID 26024978 DOI: 10.1016/j.addr.2015.05.014  1
2015 Huang S, Srimani JK, Lee AJ, Zhang Y, Lopatkin AJ, Leong KW, You L. Dynamic control and quantification of bacterial population dynamics in droplets. Biomaterials. 61: 239-45. PMID 26005763 DOI: 10.1016/j.biomaterials.2015.05.038  1
2015 Juul S, Obliosca JM, Liu C, Liu YL, Chen YA, Imphean DM, Knudsen BR, Ho YP, Leong KW, Yeh HC. NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection. Nanoscale. 7: 8332-7. PMID 25901841 DOI: 10.1039/c5nr01705j  1
2015 Lorden ER, Levinson HM, Leong KW. Integration of drug, protein, and gene delivery systems with regenerative medicine. Drug Delivery and Translational Research. 5: 168-86. PMID 25787742 DOI: 10.1007/s13346-013-0165-8  1
2015 Park JS, Suryaprakash S, Lao YH, Leong KW. Engineering mesenchymal stem cells for regenerative medicine and drug delivery. Methods (San Diego, Calif.). PMID 25770356 DOI: 10.1016/j.ymeth.2015.03.002  1
2015 Lao YH, Phua KK, Leong KW. Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation. Acs Nano. 9: 2235-54. PMID 25731717 DOI: 10.1021/nn507494p  1
2015 Wang X, Su J, Sherman A, Rogers GL, Liao G, Hoffman BE, Leong KW, Terhorst C, Daniell H, Herzog RW. Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells. Blood. 125: 2418-27. PMID 25700434 DOI: 10.1182/blood-2014-08-597070  0.44
2015 Lorden ER, Miller KJ, Bashirov L, Ibrahim MM, Hammett E, Jung Y, Medina MA, Rastegarpour A, Selim MA, Leong KW, Levinson H. Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold. Biomaterials. 43: 61-70. PMID 25591962 DOI: 10.1016/j.biomaterials.2014.12.003  1
2015 Diekman BO, Thakore PI, O'Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F. Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. Tissue Engineering. Part A. 21: 1261-74. PMID 25517798 DOI: 10.1089/ten.TEA.2014.0240  1
2015 Leong KW. Editorial. Biomaterials. 36: 5. PMID 25443403 DOI: 10.1016/j.biomaterials.2014.10.047  1
2015 Zhang LG, Fisher JP, Leong KW. Preface 3d Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine. xvii-xviii. DOI: 10.1016/B978-0-12-800547-7.00020-5  1
2015 Zhang LG, Fisher JP, Leong KW. 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine 3d Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine. 1-373.  1
2014 Miller KJ, Lorden ER, Hammett E, Ibrahim MM, Quiles C, Selim A, Leong KW, Levinson H. Abstract 166: electrospun synthetic scaffolds: a biomimetic approach to prevent hypertrophic scar contraction. Plastic and Reconstructive Surgery. 133: 182-3. PMID 25942276 DOI: 10.1097/01.prs.0000444995.05926.58  1
2014 Chen Z, Atchison L, Ji H, Leong KW. Nanograting structure promotes lamellipodia-based cell collective migration and wound healing. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2014: 2916-9. PMID 25570601 DOI: 10.1109/EMBC.2014.6944233  1
2014 Kulangara K, Yang J, Chellappan M, Yang Y, Leong KW. Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells. Plos One. 9: e114698. PMID 25521962 DOI: 10.1371/journal.pone.0114698  1
2014 Chakraborty S, Ji H, Chen J, Gersbach CA, Leong KW. Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis. Scientific Reports. 4: 7403. PMID 25492703 DOI: 10.1038/srep07403  1
2014 Xing Q, Vogt C, Leong KW, Zhao F. Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts. Advanced Functional Materials. 24: 3027-3035. PMID 25484849 DOI: 10.1002/adfm.201303460  1
2014 Chakraborty S, Ji H, Kabadi AM, Gersbach CA, Christoforou N, Leong KW. A CRISPR/Cas9-based system for reprogramming cell lineage specification. Stem Cell Reports. 3: 940-7. PMID 25448066 DOI: 10.1016/j.stemcr.2014.09.013  1
2014 Ibrahim MM, Bond J, Bergeron A, Miller KJ, Ehanire T, Quiles C, Lorden ER, Medina MA, Fisher M, Klitzman B, Selim MA, Leong KW, Levinson H. A novel immune competent murine hypertrophic scar contracture model: a tool to elucidate disease mechanism and develop new therapies. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 22: 755-64. PMID 25327261 DOI: 10.1111/wrr.12238  1
2014 Lu M, Yang S, Ho YP, Grigsby CL, Leong KW, Huang TJ. Shape-controlled synthesis of hybrid nanomaterials via three-dimensional hydrodynamic focusing. Acs Nano. 8: 10026-34. PMID 25268035 DOI: 10.1021/nn502549v  1
2014 Willard VP, Diekman BO, Sanchez-Adams J, Christoforou N, Leong KW, Guilak F. Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening. Arthritis & Rheumatology (Hoboken, N.J.). 66: 3062-72. PMID 25047145 DOI: 10.1002/art.38780  1
2014 Williford JM, Wu J, Ren Y, Archang MM, Leong KW, Mao HQ. Recent advances in nanoparticle-mediated siRNA delivery. Annual Review of Biomedical Engineering. 16: 347-70. PMID 24905873 DOI: 10.1146/annurev-bioeng-071813-105119  1
2014 Phua KK, Nair SK, Leong KW. Messenger RNA (mRNA) nanoparticle tumour vaccination. Nanoscale. 6: 7715-29. PMID 24904987 DOI: 10.1039/c4nr01346h  1
2014 Phua KK, Staats HF, Leong KW, Nair SK. Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity. Scientific Reports. 4: 5128. PMID 24894817 DOI: 10.1038/srep05128  1
2014 Kulangara K, Adler AF, Wang H, Chellappan M, Hammett E, Yasuda R, Leong KW. The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. Biomaterials. 35: 5327-36. PMID 24709523 DOI: 10.1016/j.biomaterials.2014.03.034  1
2014 Chiu YL, Chan HF, Phua KK, Zhang Y, Juul S, Knudsen BR, Ho YP, Leong KW. Synthesis of fluorosurfactants for emulsion-based biological applications. Acs Nano. 8: 3913-20. PMID 24646088 DOI: 10.1021/nn500810n  1
2014 Lu M, Ho YP, Grigsby CL, Nawaz AA, Leong KW, Huang TJ. Three-dimensional hydrodynamic focusing method for polyplex synthesis. Acs Nano. 8: 332-9. PMID 24341632 DOI: 10.1021/nn404193e  1
2014 Phua KK, Boczkowski D, Dannull J, Pruitt S, Leong KW, Nair SK. Whole blood cells loaded with messenger RNA as an anti-tumor vaccine. Advanced Healthcare Materials. 3: 837-42. PMID 24339387 DOI: 10.1002/adhm.201300512  1
2014 Cao C, Chan HF, Zang J, Leong KW, Zhao X. Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality. Advanced Materials (Deerfield Beach, Fla.). 26: 1763-70. PMID 24339233 DOI: 10.1002/adma.201304589  1
2014 Hong S, Jung Y, Yen R, Chan HF, Leong KW, Truskey GA, Zhao X. Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. Lab On a Chip. 14: 514-21. PMID 24310854 DOI: 10.1039/c3lc51076j  1
2014 Boukany PE, Wu Y, Zhao X, Kwak KJ, Glazer PJ, Leong K, Lee LJ. Nonendocytic delivery of lipoplex nanoparticles into living cells using nanochannel electroporation Advanced Healthcare Materials. 3: 682-689. PMID 23996973 DOI: 10.1002/adhm.201300213  1
2014 Batinic-Haberle I, Tovmasyan A, Roberts ER, Vujaskovic Z, Leong KW, Spasojevic I. SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways. Antioxidants & Redox Signaling. 20: 2372-415. PMID 23875805 DOI: 10.1089/ars.2012.5147  1
2014 Ni W, Huang C, Liu YL, Li W, Leong KW, Wu J. POXN: A new passive optical cross-connection network for low-cost power-efficient datacenters Journal of Lightwave Technology. 32: 1482-1500. DOI: 10.1109/JLT.2013.2295599  1
2013 Godsey ME, Suryaprakash S, Leong KW. Materials innovation for co-delivery of diverse therapeutic cargos. Rsc Advances. 3: 24794-24811. PMID 24818000 DOI: 10.1039/C3RA43094D  1
2013 Truskey GA, Achneck HE, Bursac N, Chan H, Cheng CS, Fernandez C, Hong S, Jung Y, Koves T, Kraus WE, Leong K, Madden L, Reichert WM, Zhao X. Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. Stem Cell Research & Therapy. 4: S10. PMID 24565225 DOI: 10.1186/scrt371  1
2013 Chan HF, Zhang Y, Ho YP, Chiu YL, Jung Y, Leong KW. Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment. Scientific Reports. 3: 3462. PMID 24322507 DOI: 10.1038/srep03462  1
2013 Grigsby CL, Ho YP, Lin C, Engbersen JF, Leong KW. Microfluidic preparation of polymer-nucleic acid nanocomplexes improves nonviral gene transfer. Scientific Reports. 3: 3155. PMID 24193511 DOI: 10.1038/srep03155  1
2013 Juul S, Iacovelli F, Falconi M, Kragh SL, Christensen B, Frøhlich R, Franch O, Kristoffersen EL, Stougaard M, Leong KW, Ho YP, Sørensen ES, Birkedal V, Desideri A, Knudsen BR. Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage. Acs Nano. 7: 9724-34. PMID 24168393 DOI: 10.1021/nn4030543  1
2013 Son YJ, Kim H, Leong KW, Yoo HS. Multifunctional nanorods serving as nanobridges to modulate T cell-mediated immunity. Acs Nano. 7: 9771-9. PMID 24088178 DOI: 10.1021/nn403275p  1
2013 Chen J, Lee EJ, Jing L, Christoforou N, Leong KW, Setton LA. Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro. Plos One. 8: e75548. PMID 24086564 DOI: 10.1371/journal.pone.0075548  1
2013 Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. RNA-guided gene activation by CRISPR-Cas9-based transcription factors. Nature Methods. 10: 973-6. PMID 23892895 DOI: 10.1038/nmeth.2600  1
2013 Christoforou N, Liau B, Chakraborty S, Chellapan M, Bursac N, Leong KW. Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. Plos One. 8: e65963. PMID 23785459 DOI: 10.1371/journal.pone.0065963  1
2013 Chakraborty S, Christoforou N, Fattahi A, Herzog RW, Leong KW. A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells. Plos One. 8: e64342. PMID 23717601 DOI: 10.1371/journal.pone.0064342  1
2013 Christoforou N, Chellappan M, Adler AF, Kirkton RD, Wu T, Addis RC, Bursac N, Leong KW. Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. Plos One. 8: e63577. PMID 23704920 DOI: 10.1371/journal.pone.0063577  1
2013 Zhang Y, Ho YP, Chiu YL, Chan HF, Chlebina B, Schuhmann T, You L, Leong KW. A programmable microenvironment for cellular studies via microfluidics-generated double emulsions. Biomaterials. 34: 4564-72. PMID 23522800 DOI: 10.1016/j.biomaterials.2013.03.002  1
2013 Leong KW, Sung HW. Nanoparticle- and biomaterials-mediated oral delivery for drug, gene, and immunotherapy. Advanced Drug Delivery Reviews. 65: 757-8. PMID 23434918 DOI: 10.1016/j.addr.2013.02.002  1
2013 Gamboa JM, Leong KW. In vitro and in vivo models for the study of oral delivery of nanoparticles. Advanced Drug Delivery Reviews. 65: 800-10. PMID 23415952 DOI: 10.1016/j.addr.2013.01.003  1
2013 Phua KK, Leong KW, Nair SK. Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format. Journal of Controlled Release : Official Journal of the Controlled Release Society. 166: 227-33. PMID 23306021 DOI: 10.1016/j.jconrel.2012.12.029  1
2013 Peters EB, Christoforou N, Leong KW, Truskey GA. Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro. Tissue Engineering. Part A. 19: 697-706. PMID 23171167 DOI: 10.1089/ten.tea.2011.0704  1
2013 Wang X, Sherman A, Liao G, Leong KW, Daniell H, Terhorst C, Herzog RW. Mechanism of oral tolerance induction to therapeutic proteins. Advanced Drug Delivery Reviews. 65: 759-73. PMID 23123293 DOI: 10.1016/j.addr.2012.10.013  1
2013 Zhang Y, Chan HF, Leong KW. Advanced materials and processing for drug delivery: the past and the future. Advanced Drug Delivery Reviews. 65: 104-20. PMID 23088863 DOI: 10.1016/j.addr.2012.10.003  1
2013 Choy AT, Leong KW, Chan BP. Chemical modification of collagen improves glycosaminoglycan retention of their co-precipitates. Acta Biomaterialia. 9: 4661-72. PMID 23009864 DOI: 10.1016/j.actbio.2012.09.016  1
2013 Maldonado-Basilio R, Li R, Abdul-Majid S, Nikkhah H, Leong KW, Hall TJ. Effect of the degree of phase-correlation of laser sources on the transmission and optical coherent detection in radio-over-fibre systems Proceedings of Spie - the International Society For Optical Engineering. 8645. DOI: 10.1117/12.2004732  1
2013 Juul S, Harmsen C, Nielsen MJ, Stougaard M, Leong KW, Knudsen BR, Ho YP. Single cell enzyme diagnosis on the chip Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 911-914. DOI: 10.1109/MEMSYS.2013.6474392  1
2013 Lu M, Ho YP, Grigsby CL, Nawaz AA, Huang PH, Leong KW, Huang TJ. Polyplex synthesis by "microfluidic drifting" based three-dimensional hydrodynamic focusing method 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 3: 1896-1898.  1
2012 Quek CH, Leong KW. Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging. Nanomaterials (Basel, Switzerland). 2: 92-112. PMID 28348298 DOI: 10.3390/nano2020092  0.48
2012 Adler AF, Grigsby CL, Kulangara K, Wang H, Yasuda R, Leong KW. Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells. Molecular Therapy. Nucleic Acids. 1: e32. PMID 23344148 DOI: 10.1038/mtna.2012.25  1
2012 Juul S, Nielsen CJ, Labouriau R, Roy A, Tesauro C, Jensen PW, Harmsen C, Kristoffersen EL, Chiu YL, Frøhlich R, Fiorani P, Cox-Singh J, Tordrup D, Koch J, Bienvenu AL, ... ... Leong KW, et al. Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement. Acs Nano. 6: 10676-83. PMID 23121492 DOI: 10.1021/nn3038594  1
2012 Diekman BO, Christoforou N, Willard VP, Sun H, Sanchez-Adams J, Leong KW, Guilak F. Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 19172-7. PMID 23115336 DOI: 10.1073/pnas.1210422109  1
2012 Yang Y, Kulangara K, Lam RT, Dharmawan R, Leong KW. Effects of topographical and mechanical property alterations induced by oxygen plasma modification on stem cell behavior. Acs Nano. 6: 8591-8. PMID 22970773 DOI: 10.1021/nn301713d  1
2012 Jain S, Pitoc GA, Holl EK, Zhang Y, Borst L, Leong KW, Lee J, Sullenger BA. Nucleic acid scavengers inhibit thrombosis without increasing bleeding. Proceedings of the National Academy of Sciences of the United States of America. 109: 12938-43. PMID 22837404 DOI: 10.1073/pnas.1204928109  1
2012 Stearns NA, Lee J, Leong KW, Sullenger BA, Pisetsky DS. The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers. Plos One. 7: e40862. PMID 22808279 DOI: 10.1371/journal.pone.0040862  1
2012 Kolind K, Leong KW, Besenbacher F, Foss M. Guidance of stem cell fate on 2D patterned surfaces. Biomaterials. 33: 6626-33. PMID 22748769 DOI: 10.1016/j.biomaterials.2012.05.070  1
2012 Yang S, Guo F, Kiraly B, Mao X, Lu M, Leong KW, Huang TJ. Microfluidic synthesis of multifunctional Janus particles for biomedical applications. Lab On a Chip. 12: 2097-102. PMID 22584998 DOI: 10.1039/c2lc90046g  1
2012 Kulangara K, Yang Y, Yang J, Leong KW. Nanotopography as modulator of human mesenchymal stem cell function. Biomaterials. 33: 4998-5003. PMID 22516607 DOI: 10.1016/j.biomaterials.2012.03.053  1
2012 Grigsby CL, Ho YP, Leong KW. Understanding nonviral nucleic acid delivery with quantum dot-FRET nanosensors. Nanomedicine (London, England). 7: 565-77. PMID 22471720 DOI: 10.2217/nnm.12.28  1
2012 Loo Y, Grigsby CL, Yamanaka YJ, Chellappan MK, Jiang X, Mao HQ, Leong KW. Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 48-56. PMID 22326811 DOI: 10.1016/j.jconrel.2012.01.041  1
2012 St John AL, Chan CY, Staats HF, Leong KW, Abraham SN. Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nature Materials. 11: 250-7. PMID 22266469 DOI: 10.1038/nmat3222  1
2012 Pisetsky DS, Lee J, Leong KW, Sullenger BA. Nucleic acid-binding polymers as anti-inflammatory agents: reducing the danger of nuclear attack. Expert Review of Clinical Immunology. 8: 1-3. PMID 22149331 DOI: 10.1586/eci.11.82  1
2012 Ma G, Petersen E, Leong KW, Liao K. Mechanical behavior of human embryonic stem cell pellet under unconfined compression. Biomechanics and Modeling in Mechanobiology. 11: 703-14. PMID 21858691 DOI: 10.1007/s10237-011-0344-9  1
2012 Park S, Son YJ, Leong KW, Yoo HS. Therapeutic nanorods with metallic multi-segments: Thermally inducible encapsulation of doxorubicin for anti-cancer therapy Nano Today. 7: 76-84. DOI: 10.1016/j.nantod.2012.02.005  1
2012 Yang Y, Leong KW. Microfluidic Cell Culture Platforms with Embedded Nanoscale Features Microfluidic Cell Culture Systems. 3-26. DOI: 10.1016/B978-1-4377-3459-1.00001-6  1
2011 Li H, Labean TH, Leong KW. Nucleic acid-based nanoengineering: novel structures for biomedical applications. Interface Focus. 1: 702-24. PMID 23050076 DOI: 10.1098/rsfs.2011.0040  1
2011 Juul S, Ho YP, Stougaard M, Koch J, Andersen FF, Leong KW, Knudsen BR. Microfluidics-mediated isothermal detection of enzyme activity at the single molecule level. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 3258-61. PMID 22255034 DOI: 10.1109/IEMBS.2011.6090885  1
2011 Juul S, Ho YP, Koch J, Andersen FF, Stougaard M, Leong KW, Knudsen BR. Detection of single enzymatic events in rare or single cells using microfluidics. Acs Nano. 5: 8305-10. PMID 21936557 DOI: 10.1021/nn203012q  1
2011 Liau B, Christoforou N, Leong KW, Bursac N. Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function. Biomaterials. 32: 9180-7. PMID 21906802 DOI: 10.1016/j.biomaterials.2011.08.050  1
2011 Ye X, Fels D, Tovmasyan A, Aird KM, Dedeugd C, Allensworth JL, Kos I, Park W, Spasojevic I, Devi GR, Dewhirst MW, Leong KW, Batinic-Haberle I. Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate. Free Radical Research. 45: 1289-306. PMID 21859376 DOI: 10.3109/10715762.2011.616199  1
2011 Lee J, Sohn JW, Zhang Y, Leong KW, Pisetsky D, Sullenger BA. Nucleic acid-binding polymers as anti-inflammatory agents. Proceedings of the National Academy of Sciences of the United States of America. 108: 14055-60. PMID 21844380 DOI: 10.1073/pnas.1105777108  1
2011 Yuan M, Leong KW, Chan BP. Three-dimensional culture of rabbit nucleus pulposus cells in collagen microspheres. The Spine Journal : Official Journal of the North American Spine Society. 11: 947-60. PMID 21843975 DOI: 10.1016/j.spinee.2011.07.004  1
2011 Wu Y, Ho YP, Mao Y, Wang X, Yu B, Leong KW, Lee LJ. Uptake and intracellular fate of multifunctional nanoparticles: a comparison between lipoplexes and polyplexes via quantum dot mediated Förster resonance energy transfer. Molecular Pharmaceutics. 8: 1662-8. PMID 21740056 DOI: 10.1021/mp100466m  1
2011 Chalut KJ, Kulangara K, Wax A, Leong KW. Stem cell differentiation indicated by noninvasive photonic characterization and fractal analysis of subcellular architecture. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 863-7. PMID 21695342 DOI: 10.1039/c1ib00003a  1
2011 Le DM, Kulangara K, Adler AF, Leong KW, Ashby VS. Dynamic topographical control of mesenchymal stem cells by culture on responsive poly(ε-caprolactone) surfaces. Advanced Materials (Deerfield Beach, Fla.). 23: 3278-83. PMID 21626577 DOI: 10.1002/adma.201100821  1
2011 Batinic-Haberle I, Rajic Z, Tovmasyan A, Reboucas JS, Ye X, Leong KW, Dewhirst MW, Vujaskovic Z, Benov L, Spasojevic I. Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. Free Radical Biology & Medicine. 51: 1035-53. PMID 21616142 DOI: 10.1016/j.freeradbiomed.2011.04.046  1
2011 Ho YP, Grigsby CL, Zhao F, Leong KW. Tuning physical properties of nanocomplexes through microfluidics-assisted confinement. Nano Letters. 11: 2178-82. PMID 21506589 DOI: 10.1021/nl200862n  1
2011 Yang Y, Kulangara K, Sia J, Wang L, Leong KW. Engineering of a microfluidic cell culture platform embedded with nanoscale features. Lab On a Chip. 11: 1638-46. PMID 21442110 DOI: 10.1039/c0lc00736f  1
2011 Adler AF, Speidel AT, Christoforou N, Kolind K, Foss M, Leong KW. High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts. Biomaterials. 32: 3611-9. PMID 21334062 DOI: 10.1016/j.biomaterials.2011.01.040  1
2011 Sun TM, Du JZ, Yao YD, Mao CQ, Dou S, Huang SY, Zhang PZ, Leong KW, Song EW, Wang J. Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression. Acs Nano. 5: 1483-94. PMID 21204585 DOI: 10.1021/nn103349h  1
2011 Dai H, Jiang X, Leong KW, Mao HQ. Transient depletion of kupffer cells leads to enhanced transgene expression in rat liver following retrograde intrabiliary infusion of plasmid DNA and DNA nanoparticles. Human Gene Therapy. 22: 873-8. PMID 21091274 DOI: 10.1089/hum.2010.146  1
2011 Liao IC, Leong KW. Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers. Biomaterials. 32: 1669-77. PMID 21084118 DOI: 10.1016/j.biomaterials.2010.10.049  1
2011 Spasojevic I, Kos I, Benov LT, Rajic Z, Fels D, Dedeugd C, Ye X, Vujaskovic Z, Reboucas JS, Leong KW, Dewhirst MW, Batinic-Haberle I. Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site. Free Radical Research. 45: 188-200. PMID 20942564 DOI: 10.3109/10715762.2010.522575  1
2011 Ho YP, Grigsby C, Leong KW. Unexpected properties of polymeric DNA-nanocomplexes synthesized in picoliter droplets Nems 2011 - 6th Ieee International Conference On Nano/Micro Engineered and Molecular Systems. 41-44. DOI: 10.1109/NEMS.2011.6017290  1
2011 Phua KKL, Roberts ERH, Leong KW. Degradable polymers Comprehensive Biomaterials. 1: 381-415.  1
2010 Adler AF, Leong KW. Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery. Nano Today. 5: 553-569. PMID 21383869 DOI: 10.1016/j.nantod.2010.10.007  1
2010 Chalut KJ, Kulangara K, Giacomelli MG, Wax A, Leong KW. Deformation of stem cell nuclei by nanotopographical cues. Soft Matter. 6: 1675-1681. PMID 21297875 DOI: 10.1039/B921206J  1
2010 Yang Y, Leong KW. Nanoscale surfacing for regenerative medicine. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 2: 478-95. PMID 20803682 DOI: 10.1002/wnan.74  1
2010 Ho YP, Leong KW. Quantum dot-based theranostics. Nanoscale. 2: 60-8. PMID 20648364 DOI: 10.1039/b9nr00178f  1
2010 Christoforou N, Oskouei BN, Esteso P, Hill CM, Zimmet JM, Bian W, Bursac N, Leong KW, Hare JM, Gearhart JD. Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts. Plos One. 5: e11536. PMID 20634944 DOI: 10.1371/journal.pone.0011536  1
2010 Staats HF, Leong KW. Polymer hydrogels: Chaperoning vaccines. Nature Materials. 9: 537-8. PMID 20571480 DOI: 10.1038/nmat2788  1
2010 Wu Y, Liao IC, Kennedy SJ, Du J, Wang J, Leong KW, Clark RL. Electrosprayed core-shell microspheres for protein delivery. Chemical Communications (Cambridge, England). 46: 4743-5. PMID 20485844 DOI: 10.1039/c0cc00535e  1
2010 Chiang CW, Huang Y, Leong KW, Chen LC, Chen HC, Chen SJ, Chou CK. PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells. Journal of Biomedical Science. 17: 35. PMID 20444294 DOI: 10.1186/1423-0127-17-35  1
2010 Jiang X, Zheng Y, Chen HH, Leong KW, Wang TH, Mao HQ. Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency. Advanced Materials (Deerfield Beach, Fla.). 22: 2556-60. PMID 20440698 DOI: 10.1002/adma.200903933  1
2010 Zhao F, Veldhuis JJ, Duan Y, Yang Y, Christoforou N, Ma T, Leong KW. Low oxygen tension and synthetic nanogratings improve the uniformity and stemness of human mesenchymal stem cell layer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1010-8. PMID 20179678 DOI: 10.1038/mt.2010.21  1
2010 Phua K, Leong KW. Microscale oral delivery devices incorporating nanoparticles. Nanomedicine (London, England). 5: 161-3. PMID 20148626 DOI: 10.2217/nnm.09.113  1
2010 Chen S, Jones JA, Xu Y, Low HY, Anderson JM, Leong KW. Characterization of topographical effects on macrophage behavior in a foreign body response model. Biomaterials. 31: 3479-91. PMID 20138663 DOI: 10.1016/j.biomaterials.2010.01.074  1
2010 Kadiyala I, Loo Y, Roy K, Rice J, Leong KW. Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 39: 103-9. PMID 19913612 DOI: 10.1016/j.ejps.2009.11.002  1
2010 Yim EK, Darling EM, Kulangara K, Guilak F, Leong KW. Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells. Biomaterials. 31: 1299-306. PMID 19879643 DOI: 10.1016/j.biomaterials.2009.10.037  1
2010 Grigsby CL, Leong KW. Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery. Journal of the Royal Society, Interface / the Royal Society. 7: S67-82. PMID 19734186 DOI: 10.1098/rsif.2009.0260  1
2010 Ho M, Yang Y, Kulangara K, Li H, Zhao F, La Bean T, Leong KW. Microfluidic platforms related to nanomedicine 7th Annual Conference On Foundations of Nanoscience: Self-Assembled Architectures and Devices, Fnano 2010. 21-22.  1
2010 Wang Y, Quek CH, Leong KW, Fang J. Synthesis and cytotoxicity of luminescent InP quantum dots Materials Research Society Symposium Proceedings. 1241: 7-12.  1
2009 Chen HH, Ho YP, Jiang X, Mao HQ, Wang TH, Leong KW. Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET. Nano Today. 4: 125-134. PMID 20161048 DOI: 10.1016/j.nantod.2009.02.008  1
2009 Kunder CA, St John AL, Li G, Leong KW, Berwin B, Staats HF, Abraham SN. Mast cell-derived particles deliver peripheral signals to remote lymph nodes. The Journal of Experimental Medicine. 206: 2455-67. PMID 19808250 DOI: 10.1084/jem.20090805  1
2009 Oney S, Lam RT, Bompiani KM, Blake CM, Quick G, Heidel JD, Liu JY, Mack BC, Davis ME, Leong KW, Sullenger BA. Development of universal antidotes to control aptamer activity. Nature Medicine. 15: 1224-8. PMID 19801990 DOI: 10.1038/nm.1990  1
2009 Ho YP, Chen HH, Leong KW, Wang TH. Combining QD-FRET and microfluidics to monitor DNA nanocomplex self-assembly in real-time. Journal of Visualized Experiments : Jove. PMID 19710626 DOI: 10.3791/1432  1
2009 Chakraborty S, Liao IC, Adler A, Leong KW. Electrohydrodynamics: A facile technique to fabricate drug delivery systems. Advanced Drug Delivery Reviews. 61: 1043-54. PMID 19651167 DOI: 10.1016/j.addr.2009.07.013  1
2009 Liao IC, Chen S, Liu JB, Leong KW. Sustained viral gene delivery through core-shell fibers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 139: 48-55. PMID 19539680 DOI: 10.1016/j.jconrel.2009.06.007  1
2009 Ho YP, Chen HH, Leong KW, Wang TH. The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time. Nanotechnology. 20: 095103. PMID 19417478 DOI: 10.1088/0957-4484/20/9/095103  1
2009 Yow SZ, Quek CH, Yim EK, Lim CT, Leong KW. Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells. Biomaterials. 30: 1133-42. PMID 19041132 DOI: 10.1016/j.biomaterials.2008.11.003  0.48
2009 Lou YL, Peng YS, Chen BH, Wang LF, Leong KW. Poly(ethylene imine)-g-chitosan using EX-810 as a spacer for nonviral gene delivery vectors. Journal of Biomedical Materials Research. Part A. 88: 1058-68. PMID 18404706 DOI: 10.1002/jbm.a.31961  1
2009 Kulangara K, Leong KW. Substrate topography shapes cell function Soft Matter. 5: 4072-4076. DOI: 10.1039/b910132m  1
2009 Yow SZ, Quek CH, Yim EKF, Leong KW, Lim CT. A Biofunctional Fibrous Scaffold for the Encapsulation of Human Mesenchymal Stem Cells and its Effects on Stem Cell Differentiation Ifmbe Proceedings. 23: 1279-1281. DOI: 10.1007/978-3-540-92841-6_314  1
2008 Liao IC, Liu JB, Bursac N, Leong KW. Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers. Cellular and Molecular Bioengineering. 1: 133-145. PMID 19774099 DOI: 10.1007/s12195-008-0021-y  0.84
2008 Yamanaka YJ, Leong KW. Engineering strategies to enhance nanoparticle-mediated oral delivery. Journal of Biomaterials Science. Polymer Edition. 19: 1549-70. PMID 19017470 DOI: 10.1163/156856208786440479  0.48
2008 Chan BP, Leong KW. Scaffolding in tissue engineering: general approaches and tissue-specific considerations. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 17: 467-79. PMID 19005702 DOI: 10.1007/s00586-008-0745-3  1
2008 Bowman K, Sarkar R, Raut S, Leong KW. Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 132: 252-9. PMID 18634839 DOI: 10.1016/j.jconrel.2008.06.019  1
2008 Chalut KJ, Chen S, Finan JD, Giacomelli MG, Guilak F, Leong KW, Wax A. Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry. Biophysical Journal. 94: 4948-56. PMID 18326642 DOI: 10.1529/biophysj.107.124107  1
2008 Chen HH, Ho YP, Jiang X, Mao HQ, Wang TH, Leong KW. Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 324-32. PMID 18180773 DOI: 10.1038/sj.mt.6300392  1
2008 Chew SY, Mi R, Hoke A, Leong KW. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials. 29: 653-61. PMID 17983651 DOI: 10.1016/j.biomaterials.2007.10.025  0.6
2007 Chew SY, Mi R, Hoke A, Leong KW. Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform. Advanced Functional Materials. 17: 1288-1296. PMID 18618021 DOI: 10.1002/adfm.200600441  0.6
2007 Dang JM, Leong KW. Myogenic Induction of Aligned Mesenchymal Stem Cell Sheets by Culture on Thermally Responsive Electrospun Nanofibers. Advanced Materials (Deerfield Beach, Fla.). 19: 2775-2779. PMID 18584057 DOI: 10.1002/adma.200602159  1
2007 Yim EK, Liao IC, Leong KW. Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: evaluation of blood compatibility and biocompatibility. Tissue Engineering. 13: 423-33. PMID 17518574 DOI: 10.1089/ten.2006.0113  1
2006 Liao IC, Chew SY, Leong KW. Aligned core-shell nanofibers delivering bioactive proteins. Nanomedicine (London, England). 1: 465-71. PMID 17716148 DOI: 10.2217/17435889.1.4.465  1
2006 Yim EK, Wan AC, Le Visage C, Liao IC, Leong KW. Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold. Biomaterials. 27: 6111-22. PMID 16919722 DOI: 10.1016/j.biomaterials.2006.07.037  1
2006 Lim SH, Liao IC, Leong KW. Nonviral gene delivery from nonwoven fibrous scaffolds fabricated by interfacial complexation of polyelectrolytes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 1163-72. PMID 16497560 DOI: 10.1016/j.ymthe.2005.12.016  1
2005 Lu HF, Lim WS, Zhang PC, Chia SM, Yu H, Mao HQ, Leong KW. Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture. Tissue Engineering. 11: 1667-77. PMID 16411812 DOI: 10.1089/ten.2005.11.1667  1
2005 Chia SM, Lin PC, Quek CH, Yin C, Mao HQ, Leong KW, Xu X, Goh CH, Ng ML, Yu H. Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells. Journal of Biotechnology. 118: 434-47. PMID 16026880 DOI: 10.1016/j.jbiotec.2005.05.012  1
2005 Liao IC, Wan AC, Yim EK, Leong KW. Controlled release from fibers of polyelectrolyte complexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 104: 347-58. PMID 15907585 DOI: 10.1016/j.jconrel.2005.02.013  1
2004 Wan AC, Yim EK, Liao IC, Le Visage C, Leong KW. Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering. Journal of Biomedical Materials Research. Part A. 71: 586-95. PMID 15499568 DOI: 10.1002/jbm.a.30158  1
2004 Wang J, Lee IL, Lim WS, Chia SM, Yu H, Leong KW, Mao HQ. Evaluation of collagen and methylated collagen as gene carriers. International Journal of Pharmaceutics. 279: 115-26. PMID 15234800 DOI: 10.1016/j.ijpharm.2004.04.014  1
2004 Quek CH, Li J, Sun T, Chan ML, Mao HQ, Gan LM, Leong KW, Yu H. Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation. Biomaterials. 25: 3531-40. PMID 15020127 DOI: 10.1016/j.biomaterials.2003.09.112  1
2004 Li Y, Wang J, Lee CG, Wang CY, Gao SJ, Tang GP, Ma YX, Yu H, Mao HQ, Leong KW, Wang S. CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes. Gene Therapy. 11: 109-14. PMID 14681704 DOI: 10.1038/sj.gt.3302135  1
2003 Lu HF, Lim WS, Wang J, Tang ZQ, Zhang PC, Leong KW, Chia SM, Yu H, Mao HQ. Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance. Biomaterials. 24: 4893-903. PMID 14559002  1
2003 Sun T, Chan ML, Zhou Y, Xu X, Zhang J, Lao X, Wang X, Quek CH, Chen JP, Leong KW, Yu H. Use of ultrathin shell microcapsules of hepatocytes in bioartificial liver-assist device. Tissue Engineering. 9: S65-75. PMID 14511471 DOI: 10.1089/10763270360696987  1
2003 Xu X, Yee WC, Hwang PY, Yu H, Wan AC, Gao S, Boon KL, Mao HQ, Leong KW, Wang S. Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. Biomaterials. 24: 2405-12. PMID 12699678  1
2003 Yin C, Mien Chia S, Hoon Quek C, Yu H, Zhuo RX, Leong KW, Mao HQ. Microcapsules with improved mechanical stability for hepatocyte culture. Biomaterials. 24: 1771-80. PMID 12593959  1
2002 Xu X, Yu H, Gao S, Ma HQ, Leong KW, Wang S. Polyphosphoester microspheres for sustained release of biologically active nerve growth factor. Biomaterials. 23: 3765-72. PMID 12109702  1
2002 Chia SM, Wan AC, Quek CH, Mao HQ, Xu X, Shen L, Ng ML, Leong KW, Yu H. Multi-layered microcapsules for cell encapsulation. Biomaterials. 23: 849-56. PMID 11774851  1
2001 Wang S, Ma N, Gao SJ, Yu H, Leong KW. Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA complexes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 658-64. PMID 11356070 DOI: 10.1006/mthe.2001.0324  1
2001 Wang S, Wan AC, Xu X, Gao S, Mao HQ, Leong KW, Yu H. A new nerve guide conduit material composed of a biodegradable poly(phosphoester). Biomaterials. 22: 1157-69. PMID 11352095  1
2001 Wan AC, Mao HQ, Wang S, Leong KW, Ong LK, Yu H. Fabrication of poly(phosphoester) nerve guides by immersion precipitation and the control of porosity. Biomaterials. 22: 1147-56. PMID 11352094  1
2000 Chia SM, Leong KW, Li J, Xu X, Zeng K, Er PN, Gao S, Yu H. Hepatocyte encapsulation for enhanced cellular functions. Tissue Engineering. 6: 481-95. PMID 11074935 DOI: 10.1089/107632700750022134  0.68
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