| Year |
Citation |
Score |
| 2024 |
Kim JH, Schulte AJ, Sarver AL, Lee D, Angelos MG, Frantz AM, Forster CL, O'Brien TD, Cornax I, O'Sullivan MG, Cheng N, Lewellen M, Oseth L, Kumar S, Bullman S, ... ... Modiano JF, et al. Hemangiosarcoma Cells Promote Conserved Host-Derived Hematopoietic Expansion. Cancer Research Communications. PMID 38757809 DOI: 10.1158/2767-9764.CRC-23-0441 |
0.794 |
|
| 2023 |
Sarver AL, Mills LJ, Makielski KM, Temiz NA, Wang J, Spector LG, Subramanian S, Modiano JF. Distinct mechanisms of PTEN inactivation in dogs and humans highlight convergent molecular events that drive cell division in the pathogenesis of osteosarcoma. Cancer Genetics. 1-11. PMID 37267683 DOI: 10.1016/j.cancergen.2023.05.001 |
0.309 |
|
| 2021 |
Luong N, Lenz JA, Modiano JF, Olson JK. Extracellular Vesicles Secreted by Tumor Cells Promote the Generation of Suppressive Monocytes. Immunohorizons. 5: 647-658. PMID 34404719 DOI: 10.4049/immunohorizons.2000017 |
0.364 |
|
| 2020 |
Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ. Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer. Plos One. 15: e0224775. PMID 32084139 DOI: 10.1371/Journal.Pone.0224775 |
0.442 |
|
| 2020 |
Trott JF, Abu Aboud O, McLaughlin B, Anderson KL, Modiano JF, Kim K, Jen K, Senapedis W, Chang H, Landesman Y, Baloglu E, Pili R, Weiss RH. Anti-Cancer Activity of PAK4/NAMPT Inhibitor and Programmed Cell Death Protein-1 Antibody in Kidney Cancer Kidney360. 1: 376-388. DOI: 10.34067/Kid.0000282019 |
0.397 |
|
| 2020 |
Modiano JF, DePauw TA, Khammanivong A, Schulte AJ, Winter AL, Kim J, Stuebner K, Fahrenkrug A, Vallera DA, Borgatti A, Dickerson EB, Henson MS. Abstract 4592: Early detection for strategic prevention of a terminal canine cancer: A model to reduce the impact of cancer in our society Cancer Research. 80: 4592-4592. DOI: 10.1158/1538-7445.Am2020-4592 |
0.35 |
|
| 2020 |
Kim JH, Megquier K, Sarver AL, Thomas R, Schulte AJ, Wang C, Elvers I, Karlsson E, Breen M, Lindblad-Toh K, Modiano JF. Abstract 195: Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma Cancer Research. 80: 195-195. DOI: 10.1158/1538-7445.Am2020-195 |
0.383 |
|
| 2019 |
Langsten KL, Kim JH, Sarver AL, Dewhirst M, Modiano JF. Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment. Frontiers in Oncology. 9: 1185. PMID 31788448 DOI: 10.3389/Fonc.2019.01185 |
0.415 |
|
| 2019 |
Gingrich AA, Modiano JF, Canter RJ. Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. Journal of Clinical Medicine. 8. PMID 31717876 DOI: 10.3390/Jcm8111802 |
0.418 |
|
| 2019 |
Megquier K, Turner-Maier J, Swofford R, Kim JH, Sarver AL, Wang C, Sakthikumar S, Johnson J, Koltookian M, Lewellen M, Scott MC, Graef AJ, Borst L, Tonomura N, Alfoldi J, ... ... Modiano JF, et al. Comparative genomics reveals shared mutational landscape in canine hemangiosarcoma and human angiosarcoma. Molecular Cancer Research : McR. PMID 31570656 DOI: 10.1158/1541-7786.Mcr-19-0221 |
0.342 |
|
| 2019 |
Anderson KL, Snyder KM, Ito D, Lins DC, Mills LJ, Weiskopf K, Ring NG, Ring AM, Shimizu Y, Mescher MF, Weissman IL, Modiano JF. Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade. Melanoma Research. PMID 31205227 DOI: 10.1097/Cmr.0000000000000629 |
0.387 |
|
| 2019 |
Makielski KM, Mills LJ, Sarver AL, Henson MS, Spector LG, Naik S, Modiano JF. Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review. Veterinary Sciences. 6. PMID 31130627 DOI: 10.3390/Vetsci6020048 |
0.348 |
|
| 2019 |
Diessner BJ, Marko TA, Scott RM, Eckert AL, Stuebner KM, Hohenhaus AE, Selting KA, Largaespada DA, Modiano JF, Spector LG. A comparison of risk factors for metastasis at diagnosis in humans and dogs with osteosarcoma. Cancer Medicine. PMID 31006987 DOI: 10.1002/Cam4.2177 |
0.311 |
|
| 2019 |
Anderson KL, Snyder KM, Ito D, Lins DC, Mills LJ, Weiskopf K, Ring NG, Ring AM, Shimizu Y, Mescher MF, Weissman IL, Modiano JF. Abstract A051: Melanoma displays an evolutionarily conserved resistance to upregulation of prophagocytic signals and to CD47 blockade Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A051 |
0.43 |
|
| 2018 |
Kim JH, Frantz AM, Anderson KL, Graef AJ, Scott MC, Robinson S, Sharkey LC, O'Brien TD, Dickerson EB, Modiano JF. Corrigendum to: "Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment" [Exp. Cell. Res. 2014 15 323(1) 155-64]. Experimental Cell Research. PMID 30017210 DOI: 10.1016/J.Yexcr.2018.07.012 |
0.776 |
|
| 2018 |
Sakthikumar S, Elvers I, Kim J, Arendt ML, Thomas R, Turner-Maier J, Swofford R, Johnson J, Schumacher SE, Alföldi J, Axelsson E, Couto G, Kisseberth W, Pettersson ME, Getz G, ... ... Modiano JF, et al. SETD2 is recurrently mutated in whole-exome sequenced canine osteosarcoma. Cancer Research. PMID 29724721 DOI: 10.1158/0008-5472.Can-17-3558 |
0.33 |
|
| 2018 |
Scott M, Temiz N, Sarver A, LaRue R, Rathe S, Varshney J, Wolf N, Moriarity B, Obrien T, Spector L, Largaespada D, Modiano J, Subramanian S, Sarver A. Abstract PR14: Immune cell transcript levels, metastatic progression, and survival in osteosarcoma: A comparative transcriptome analysis Omics a Journal of Integrative Biology. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr14 |
0.449 |
|
| 2018 |
Sarver AL, Mills L, Temiz N, Scott M, Sarver A, Spector L, Wang J, Breen M, Subramanian S, Moriarity B, Modiano J, Largaespada D. Abstract 3399: Comparative genomic analyses of osteosarcoma etiology reveal a chromosomal structural rationale for the increased incidence of osteosarcoma in dogs Cancer Research. 78: 3399-3399. DOI: 10.1158/1538-7445.Am2018-3399 |
0.403 |
|
| 2018 |
Camilleri ET, Beckmann PJ, Larson JD, Kurata M, Shu J, Pope E, Hudson WA, Temiz NA, Rathe SK, LaRue RS, Sarver AE, Scott MC, Varshney J, Modiano JF, Moriarity BS, et al. Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression Cancer Research. 78: 2264-2264. DOI: 10.1158/1538-7445.Am2018-2264 |
0.439 |
|
| 2017 |
Canter RJ, Grossenbacher SK, Foltz JA, Sturgill IR, Park JS, Luna JI, Kent MS, Culp WTN, Chen M, Modiano JF, Monjazeb AM, Lee DA, Murphy WJ. Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial. Journal For Immunotherapy of Cancer. 5: 98. PMID 29254507 DOI: 10.1186/S40425-017-0305-7 |
0.322 |
|
| 2017 |
Kim JH, Frantz AM, Sarver AL, Gorden Klukas BH, Lewellen M, O'Brien TD, Dickerson EB, Modiano JF. Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers. Veterinary and Comparative Oncology. PMID 29152836 DOI: 10.1111/Vco.12368 |
0.776 |
|
| 2017 |
Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma. Cancer Research. PMID 29066513 DOI: 10.1158/0008-5472.Can-17-0576 |
0.453 |
|
| 2017 |
Cannon CM, Trembley JH, Kren BT, Unger GM, O'Sullivan MG, Cornax I, Modiano JF, Ahmed K. Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats. American Journal of Veterinary Research. 78: 946-953. PMID 28738012 DOI: 10.2460/Ajvr.78.8.946 |
0.373 |
|
| 2017 |
Cannon C, Trembley J, Kren B, Unger G, O'Sullivan MG, Cornax I, Modiano J, Ahmed K. Therapeutic targeting of protein kinase CK2 gene expression in feline oral squamous cell carcinoma - a naturally occurring large animal model of head and neck cancer. Human Gene Therapy. Clinical Development. PMID 28335614 DOI: 10.1089/Humc.2017.008 |
0.406 |
|
| 2017 |
Borgatti A, Koopmeiners JS, Sarver AL, Winter AL, Stuebner K, Todhunter D, Rizzardi AE, Henricksen JC, Schmechel S, Forster CL, Kim JH, Froelich J, Walz J, Henson MS, Breen M, ... ... Modiano JF, et al. Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR. Molecular Cancer Therapeutics. PMID 28193671 DOI: 10.1158/1535-7163.Mct-16-0637 |
0.379 |
|
| 2017 |
Murahari S, Jalkanen AL, Kulp SK, Chen CS, Modiano JF, London CA, Kisseberth WC. Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis. Bmc Cancer. 17: 67. PMID 28109246 DOI: 10.1186/S12885-017-3046-6 |
0.348 |
|
| 2017 |
Ito D, Childress M, Mason N, Winter A, O’Brien T, Henson M, Borgatti A, Lewellen M, Krick E, Stewart J, Lahrman S, Rajwa B, Scott MC, Seelig D, Koopmeiners J, ... ... Modiano J, et al. A double blinded, placebo-controlled pilot study to examine reduction of CD34+/CD117+/CD133+ lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma F1000research. 4: 42. DOI: 10.12688/F1000Research.6055.2 |
0.378 |
|
| 2017 |
Anderson KL, Snyder KM, Lins D, Weiskopf K, Shimizu Y, Weissman I, Mescher M, Modiano J. Abstract A65: Mechanisms of melanoma cell resistance to phagocytosis Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A65 |
0.475 |
|
| 2016 |
Park JS, Withers SS, Modiano JF, Kent MS, Chen M, Luna JI, Culp WT, Sparger EE, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. Canine cancer immunotherapy studies: linking mouse and human. Journal For Immunotherapy of Cancer. 4: 97. PMID 28031824 DOI: 10.1186/S40425-016-0200-7 |
0.354 |
|
| 2016 |
Im KS, Kim JH, Graef AJ, Cornax I, Seelig DM, O'Sullivan MG, Kovi RC, Modiano JF. Establishment of a Patient-Derived Xenograft of Canine Enteropathy-Associated T-Cell Lymphoma, Large Cell Type. Journal of Comparative Pathology. PMID 28011041 DOI: 10.1016/J.Jcpa.2016.11.271 |
0.395 |
|
| 2016 |
Seelig DM, Ito D, Forster CL, Yoon UA, Breen M, Burns LJ, Bachanova V, Lindblad-Toh K, O'Brien TD, Schmechel SC, Rizzardi AE, Modiano JF, Linden MA. Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies. Leukemia & Lymphoma. 1-9. PMID 27931134 DOI: 10.1080/10428194.2016.1260122 |
0.456 |
|
| 2016 |
Scott MC, Tomiyasu H, Garbe JR, Cornax I, Amaya C, O'Sullivan MG, Subramanian S, Bryan BA, Modiano JF. Heterotypic models of osteosarcoma recapitulate tumor heterogeneity and biological behavior. Disease Models & Mechanisms. PMID 27874835 DOI: 10.1242/Dmm.026849 |
0.427 |
|
| 2016 |
Weiskopf K, Anderson KL, Ito D, Schnorr PJ, Tomiyasu H, Ring AM, Bloink K, Efe J, Rue S, Lowery D, Barkal A, Prohaska S, McKenna KM, Cornax I, O'Brien TD, ... ... Modiano JF, et al. Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20. Cancer Immunology Research. PMID 27856424 DOI: 10.1158/2326-6066.Cir-16-0105 |
0.353 |
|
| 2016 |
Fenger JM, Roberts RD, Iwenofu OH, Bear MD, Zhang X, Couto JI, Modiano JF, Kisseberth WC, London CA. MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines. Bmc Cancer. 16: 784. PMID 27724924 DOI: 10.1186/S12885-016-2837-5 |
0.304 |
|
| 2016 |
Trott JF, Kim J, Aboud OA, Wettersten H, Stewart B, Berryhill G, Uzal F, Hovey RC, Chen CH, Anderson K, Graef A, Sarver AL, Modiano JF, Weiss RH. Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. Oncotarget. PMID 27572319 DOI: 10.18632/Oncotarget.11658 |
0.391 |
|
| 2016 |
Lin W, Modiano JF, Ito D. Stage-specific embryonic antigen (SSEA): determining the expression in canine glioblastoma, melanoma, and mammary cancer cells. Journal of Veterinary Science. PMID 27456773 DOI: 10.4142/Jvs.2017.18.1.101 |
0.413 |
|
| 2016 |
Modiano JF, Bellgrau D. Fas ligand based immunotherapy: A potent and effective neoadjuvant with checkpoint inhibitor properties, or a systemically toxic promoter of tumor growth? Discovery Medicine. 21: 109-16. PMID 27011046 |
0.304 |
|
| 2016 |
Anderson KL, Lins D, Volkmer J, Shimizu Y, Weissman IL, Mescher M, Modiano J. Abstract A143: Melanoma cell resistance to phagocytosis is unrelated to expression of conventional “eat-me/don't eat-me” signals Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A143 |
0.462 |
|
| 2015 |
Kim JH, Graef AJ, Dickerson EB, Modiano JF. Pathobiology of Hemangiosarcoma in Dogs: Research Advances and Future Perspectives. Veterinary Sciences. 2: 388-405. PMID 29061949 DOI: 10.3390/Vetsci2040388 |
0.436 |
|
| 2015 |
Ritt MG, Lindborg BA, O'Brien TD, Bisignano J, Modiano JF. Stimulation with Concanavalin-A Induces IL-17 Production by Canine Peripheral T Cells. Veterinary Sciences. 2: 43-51. PMID 29061930 DOI: 10.3390/Vetsci2020043 |
0.366 |
|
| 2015 |
Anderson KL, Modiano JF. Progress in Adaptive Immunotherapy for Cancer in Companion Animals: Success on the Path to a Cure. Veterinary Sciences. 2: 363-387. PMID 27066495 DOI: 10.3390/Vetsci2040363 |
0.319 |
|
| 2015 |
Scott MC, Sarver AL, Tomiyasu H, Cornax I, Van Etten J, Varshney J, O'Sullivan MG, Subramanian S, Modiano JF. Aberrant RB-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma. The Journal of Biological Chemistry. PMID 26378234 DOI: 10.1074/Jbc.M115.679696 |
0.409 |
|
| 2015 |
Elvers I, Turner-Maier J, Swofford R, Koltookian M, Johnson J, Stewart C, Zhang CZ, Schumacher SE, Beroukhim R, Rosenberg M, Thomas R, Mauceli E, Getz G, di Palma F, Modiano JF, et al. Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background. Genome Research. PMID 26377837 DOI: 10.1101/Gr.194449.115 |
0.411 |
|
| 2015 |
Im KS, Graef AJ, Breen M, Lindblad-Toh K, Modiano JF, Kim JH. Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma. Veterinary and Comparative Oncology. PMID 26337509 DOI: 10.1111/Vco.12165 |
0.418 |
|
| 2015 |
Modiano JF, Lindborg BA, McElmurry RT, Lewellen M, Forster CL, Zamora EA, Schaack J, Bellgrau D, O'Brien TD, Tolar J. Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment. Cancer Immunology, Immunotherapy : Cii. 64: 1449-60. PMID 26250807 DOI: 10.1007/S00262-015-1749-6 |
0.433 |
|
| 2015 |
Rodriguez AM, Graef AJ, LeVine DN, Cohen IR, Modiano JF, Kim JH. Association of Sphingosine-1-phosphate (S1P)/S1P Receptor-1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. PMID 26118793 DOI: 10.1111/Jvim.13570 |
0.35 |
|
| 2015 |
Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, ... Modiano JF, et al. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. Nature Genetics. 47: 615-24. PMID 25961939 DOI: 10.1038/Ng.3293 |
0.333 |
|
| 2015 |
Tonomura N, Elvers I, Thomas R, Megquier K, Turner-Maier J, Howald C, Sarver AL, Swofford R, Frantz AM, Ito D, Mauceli E, Arendt M, Noh HJ, Koltookian M, Biagi T, ... ... Modiano JF, et al. Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. Plos Genetics. 11: e1004922. PMID 25642983 DOI: 10.1371/Journal.Pgen.1004922 |
0.786 |
|
| 2015 |
Ito D, Brewer S, Modiano JF, Beall MJ. Development of a novel anti-canine CD20 monoclonal antibody with diagnostic and therapeutic potential. Leukemia & Lymphoma. 56: 219-25. PMID 24724777 DOI: 10.3109/10428194.2014.914193 |
0.396 |
|
| 2015 |
Cannon CM, Pozniak J, Scott MC, Ito D, Gorden BH, Graef AJ, Modiano JF. Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors. Veterinary and Comparative Oncology. 13: 48-59. PMID 23410058 DOI: 10.1111/Vco.12018 |
0.328 |
|
| 2015 |
Canter R, Grossenbacher S, Park J, Modiano J, Miller J, Ames E, Mac S, Monjazeb A, Kent M, Culp W, Chen M, Murphy W. Combination radioimmunotherapy with adoptive NK transfer to target cancer stem cells in canine models of sarcoma F1000research. 4. DOI: 10.7490/F1000Research.1111170.1 |
0.334 |
|
| 2015 |
Canter R, Grossenbacher SK, Park JS, Modiano J, Ames E, Mac S, Monjazeb AM, Kent M, Culp W, Chen M, Murphy W. Combination radioimmunotherapy with adoptive NK transfer targets cancer stem cells in canine models of bone and soft tissue sarcoma Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P4 |
0.388 |
|
| 2015 |
Borgatti A, Winter A, Stuebner K, Koopmeiners J, Modiano JF, Vallera D. Abstract 1694: Preclinical evaluation of a novel bispecific targeted toxin for the treatment of sarcomas Cancer Research. 75: 1694-1694. DOI: 10.1158/1538-7445.Am2015-1694 |
0.364 |
|
| 2014 |
May SL, Zhou Q, Lewellen M, Carter CM, Coffey D, Highfill SL, Bucher CM, Matise I, Morse HC, O'Sullivan MG, Schutten M, Johnson C, Bellgrau D, Blazar BR, Modiano JF. Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis. Plos One. 9: e100629. PMID 24945807 DOI: 10.1371/Journal.Pone.0100629 |
0.38 |
|
| 2014 |
Ito D, Frantz AM, Modiano JF. Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications. Veterinary Immunology and Immunopathology. 159: 192-201. PMID 24642290 DOI: 10.1016/J.Vetimm.2014.02.016 |
0.771 |
|
| 2014 |
Thomas R, Borst L, Rotroff D, Motsinger-Reif A, Lindblad-Toh K, Modiano JF, Breen M. Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 22: 305-19. PMID 24599718 DOI: 10.1007/S10577-014-9406-Z |
0.346 |
|
| 2014 |
Kim JH, Frantz AM, Anderson KL, Graef AJ, Scott MC, Robinson S, Sharkey LC, O'Brien TD, Dickerson EB, Modiano JF. Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment. Experimental Cell Research. 323: 155-64. PMID 24582862 DOI: 10.1016/J.Yexcr.2014.02.020 |
0.756 |
|
| 2014 |
Gorden BH, Kim JH, Sarver AL, Frantz AM, Breen M, Lindblad-Toh K, O'Brien TD, Sharkey LC, Modiano JF, Dickerson EB. Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization. The American Journal of Pathology. 184: 985-95. PMID 24525151 DOI: 10.1016/J.Ajpath.2013.12.025 |
0.784 |
|
| 2014 |
London CA, Bernabe LF, Barnard S, Kisseberth WC, Borgatti A, Henson M, Wilson H, Jensen K, Ito D, Modiano JF, Bear MD, Pennell ML, Saint-Martin JR, McCauley D, Kauffman M, et al. Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study. Plos One. 9: e87585. PMID 24503695 DOI: 10.1371/Journal.Pone.0087585 |
0.32 |
|
| 2014 |
Borgatti A, Duckett M, Charles S, Modiano JF. Binding of VEGF-A to canine cancer cells with preferential expression of VEGFR1 Veterinary World. 7: 1-6. DOI: 10.14202/Vetworld.2014.1-6 |
0.381 |
|
| 2014 |
Scott MC, Sarver AL, Phan F, Gupta R, Thayanithy V, Subramanian S, Modiano JF. Abstract B19: RB function as a central component of osteosarcoma behavior: A comparative assessment in dogs and humans Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B19 |
0.446 |
|
| 2014 |
Thomas R, Simpson M, Mochizuki H, Williams C, Poorman K, Kennedy K, Mazcko C, Modiano JF, Breen M. Abstract A51: Quality control and quality assurance of canine biological specimens available through the Pfizer-CCOGC, Inc. National Biorepository for Comparative Oncology Studies Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-A51 |
0.354 |
|
| 2014 |
Fenger JM, Couto JI, Bear MD, Volinia S, Modiano JF, Breen M, London CA, Kisseberth WC. Abstract 540: Characterization of miR-9 expression and activation in canine osteosarcoma Cancer Research. 74: 540-540. DOI: 10.1158/1538-7445.Am2014-540 |
0.327 |
|
| 2014 |
Anderson KL, Ito D, Lins DC, Curtsinger JM, Mescher MF, Modiano JF. Abstract 4082: CD47 blockade to enhance adaptive anti-tumor immune responses Cancer Research. 74: 4082-4082. DOI: 10.1158/1538-7445.Am2014-4082 |
0.405 |
|
| 2014 |
London CA, Bernabe LF, Barnard S, Kisseberth W, Borgatti A, Henson M, Wilson-Robles H, Jensen K, Ito D, Modiano J, Bear M, Pennell M, Saint-Martin J, McCauley D, Kauffman M, et al. Abstract 3809: Evaluation of the novel, orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in spontaneous canine cancer: Results of phase I and phase II clinical trials Cancer Research. 74: 3809-3809. DOI: 10.1158/1538-7445.Am2014-3809 |
0.381 |
|
| 2013 |
Michael HT, Ito D, McCullar V, Zhang B, Miller JS, Modiano JF. Isolation and characterization of canine natural killer cells. Veterinary Immunology and Immunopathology. 155: 211-7. PMID 23876304 DOI: 10.1016/J.Vetimm.2013.06.013 |
0.432 |
|
| 2013 |
Culver S, Ito D, Borst L, Bell JS, Modiano JF, Breen M. Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy. Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology. 42: 314-22. PMID 23800034 DOI: 10.1111/Vcp.12055 |
0.359 |
|
| 2013 |
Stiles JM, Amaya C, Rains S, Diaz D, Pham R, Battiste J, Modiano JF, Kokta V, Boucheron LE, Mitchell DC, Bryan BA. Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma. Plos One. 8: e60021. PMID 23555867 DOI: 10.1371/Journal.Pone.0060021 |
0.367 |
|
| 2013 |
Schappa JT, Frantz AM, Gorden BH, Dickerson EB, Vallera DA, Modiano JF. Hemangiosarcoma and its cancer stem cell subpopulation are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors. International Journal of Cancer. 133: 1936-44. PMID 23553371 DOI: 10.1186/1753-6561-7-S2-P34 |
0.78 |
|
| 2013 |
Wells JW, Evans CH, Scott MC, Rütgen BC, O'Brien TD, Modiano JF, Cvetkovic G, Tepic S. Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation Plos One. 8. PMID 23365669 DOI: 10.1371/Journal.Pone.0054464 |
0.41 |
|
| 2013 |
Sarver AL, Thayanithy V, Scott MC, Cleton-Jansen AM, Hogendoorn PC, Modiano JF, Subramanian S. MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma. Orphanet Journal of Rare Diseases. 8: 7. PMID 23311495 DOI: 10.1186/1750-1172-8-7 |
0.313 |
|
| 2013 |
Frantz AM, Sarver AL, Ito D, Phang TL, Karimpour-Fard A, Scott MC, Valli VE, Lindblad-Toh K, Burgess KE, Husbands BD, Henson MS, Borgatti A, Kisseberth WC, Hunter LE, Breen M, ... ... Modiano JF, et al. Molecular profiling reveals prognostically significant subtypes of canine lymphoma. Veterinary Pathology. 50: 693-703. PMID 23125145 DOI: 10.1177/0300985812465325 |
0.786 |
|
| 2013 |
Kim J, Anderson KL, Frantz AM, Graef AJ, Scott MC, Sharkey LC, O’Brien TD, Dickerson EB, Modiano JF. Constitutive expression and roles of interleukin-8 in canine hemangiosarcoma Bmc Proceedings. 7. DOI: 10.1186/1753-6561-7-S2-P35 |
0.74 |
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| 2013 |
Ito D, Modiano JF. Characterizing the role of the alternative NF-κB pathway in diffuse large B-cell lymphoma Bmc Proceedings. 7. DOI: 10.1186/1753-6561-7-S2-O2 |
0.354 |
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| 2013 |
London C, Bernabe Lf, Barnard S, Kisseberth W, Borgatti A, Henson M, Wilson H, Jensen K, Ito D, Modiano J, Bear M, Pennell M, Saint-Martin J, McCauley D, Shacham S, et al. Evaluation Of The Novel, Orally Bioavailable Selective Inhibitor Of Nuclear Export (SINE) Verdinexor (KPT-335) In Spontaneous Canine Cancer: Results Of Phase I and Phase II Clinical Trials Blood. 122: 5149-5149. DOI: 10.1182/Blood.V122.21.5149.5149 |
0.379 |
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| 2012 |
Angstadt AY, Thayanithy V, Subramanian S, Modiano JF, Breen M. A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations. Cancer Genetics. 205: 572-87. PMID 23137772 DOI: 10.1016/J.Cancergen.2012.09.005 |
0.323 |
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| 2012 |
Thayanithy V, Park C, Sarver AL, Kartha RV, Korpela DM, Graef AJ, Steer CJ, Modiano JF, Subramanian S. Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. Plos One. 7: e43720. PMID 22957032 DOI: 10.1371/Journal.Pone.0043720 |
0.322 |
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| 2012 |
Modiano JF, Bellgrau D, Cutter GR, Lana SE, Ehrhart NP, Ehrhart E, Wilke VL, Charles JB, Munson S, Scott MC, Pozniak J, Carlson CS, Schaack J, Duke RC. Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2234-43. PMID 22850679 DOI: 10.1038/Mt.2012.149 |
0.383 |
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| 2012 |
Ito D, Frantz AM, Williams C, Thomas R, Burnett RC, Avery AC, Breen M, Mason NJ, O'Brien TD, Modiano JF. CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies. Leukemia & Lymphoma. 53: 1390-8. PMID 22229753 DOI: 10.3109/10428194.2011.654337 |
0.796 |
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| 2012 |
Shacham S, Barnard S, Kisseberth W, Ito D, Jensen K, Borgotti A, Henson M, Wilson H, McCauley D, Modiano J, Kauffman M, London C. Results of a Phase I Dose Escalation Study of the Novel, Oral CRM1 Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Dogs with Spontaneous Non-Hodgkin's Lymphomas (NHL) Blood. 120: 161-161. DOI: 10.1182/Blood.V120.21.161.161 |
0.354 |
|
| 2012 |
Ito D, O'Brien TD, Modiano JF. Abstract 3482: Validation of novel therapeutic targets for T-cell non-Hodgkin lymphoma Cancer Research. 72: 3482-3482. DOI: 10.1158/1538-7445.Am2012-3482 |
0.513 |
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| 2012 |
Fenger JM, Volinia S, Jalkanen A, Ozer HG, Sarver AL, Subramanian S, Breen M, Modiano J, London C, Kisseberth W. Abstract 184: Breed-associated differential microRNA expression in canine osteosarcoma Cancer Research. 72: 184-184. DOI: 10.1158/1538-7445.Am2012-184 |
0.322 |
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| 2011 |
Angstadt AY, Motsinger-Reif A, Thomas R, Kisseberth WC, Guillermo Couto C, Duval DL, Nielsen DM, Modiano JF, Breen M. Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart. Genes, Chromosomes & Cancer. 50: 859-74. PMID 21837709 DOI: 10.1002/Gcc.20908 |
0.357 |
|
| 2011 |
Ito D, Endicott MM, Jubala CM, Helm KM, Burnett RC, Husbands BD, Borgatti A, Henson MS, Burgess KE, Bell JS, Kisseberth WC, Valli VE, Cutter GR, Avery AC, Hahn KA, ... ... Modiano JF, et al. A tumor-related lymphoid progenitor population supports hierarchical tumor organization in canine B-cell lymphoma. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 25: 890-6. PMID 21777289 DOI: 10.1111/J.1939-1676.2011.0756.X |
0.459 |
|
| 2011 |
Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone. 49: 356-67. PMID 21621658 DOI: 10.1016/J.Bone.2011.05.008 |
0.421 |
|
| 2011 |
Henson MS, Curtsinger JM, Larson VS, Klausner JS, Modiano JF, Mescher MF, Miller JS. Immunotherapy with autologous tumour antigen-coated microbeads (large multivalent immunogen), IL-2 and GM-CSF in dogs with spontaneous B-cell lymphoma. Veterinary and Comparative Oncology. 9: 95-105. PMID 21569195 DOI: 10.1111/J.1476-5829.2010.00234.X |
0.403 |
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| 2011 |
Thomas R, Seiser EL, Motsinger-Reif A, Borst L, Valli VE, Kelley K, Suter SE, Argyle D, Burgess K, Bell J, Lindblad-Toh K, Modiano JF, Breen M. Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas. Leukemia & Lymphoma. 52: 1321-35. PMID 21375435 DOI: 10.3109/10428194.2011.559802 |
0.358 |
|
| 2010 |
Ito D, O'Brien TD, Modiano JF. Exclusion of cytoplasmic fragments in flow cytometric analysis of lymph node samples from dogs with lymphoma using membrane-permeable violet laser-excitable DNA-binding fluorescent dye (DyeCycle Violet) Veterinary Clinical Pathology. 39: 494-498. PMID 21198735 DOI: 10.1111/J.1939-165X.2010.00252.X |
0.305 |
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| 2010 |
Tamburini BA, Phang TL, Fosmire SP, Scott MC, Trapp SC, Duckett MM, Robinson SR, Slansky JE, Sharkey LC, Cutter GR, Wojcieszyn JW, Bellgrau D, Gemmill RM, Hunter LE, Modiano JF. Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. Bmc Cancer. 10: 619. PMID 21062482 DOI: 10.1186/1471-2407-10-619 |
0.385 |
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| 2010 |
Oloris SC, Frazer-Abel AA, Jubala CM, Fosmire SP, Helm KM, Robinson SR, Korpela DM, Duckett MM, Baksh S, Modiano JF. Nicotine-mediated signals modulate cell death and survival of T lymphocytes. Toxicology and Applied Pharmacology. 242: 299-309. PMID 19896492 DOI: 10.1016/J.Taap.2009.10.020 |
0.322 |
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| 2010 |
Ito D, Avery AC, Mason NJ, O'Brien TD, Modiano JF. Abstract 4307: Characterization of a novel lymphoid progenitor population with predictive value in canine non-Hodgkin lymphoma Cancer Research. 70: 4307-4307. DOI: 10.1158/1538-7445.Am10-4307 |
0.472 |
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| 2009 |
Tamburini BA, Trapp S, Phang TL, Schappa JT, Hunter LE, Modiano JF. Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed. Plos One. 4: e5549. PMID 19461996 DOI: 10.1371/Journal.Pone.0005549 |
0.445 |
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| 2009 |
Thomas R, Wang HJ, Tsai PC, Langford CF, Fosmire SP, Jubala CM, Getzy DM, Cutter GR, Modiano JF, Breen M. Influence of genetic background on tumor karyotypes: evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 17: 365-77. PMID 19337847 DOI: 10.1007/S10577-009-9028-Z |
0.376 |
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| 2009 |
Willoughby JA, Sundar SN, Cheung M, Tin AS, Modiano J, Firestone GL. Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression. The Journal of Biological Chemistry. 284: 2203-13. PMID 19017637 DOI: 10.1074/Jbc.M804491200 |
0.332 |
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| 2009 |
Jubala CM, Lamerato-Kozicki AR, Borakove M, Lang J, Gardner LA, Coffey D, Helm KM, Schaack J, Baier M, Cutter GR, Bellgrau D, Modiano JF. MHC-dependent desensitization of intrinsic anti-self reactivity. Cancer Immunology, Immunotherapy : Cii. 58: 171-85. PMID 18523772 DOI: 10.1007/S00262-008-0535-0 |
0.388 |
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| 2008 |
Modiano JF, Johnson LD, Bellgrau D. Negative regulators in homeostasis of naïve peripheral T cells. Immunologic Research. 41: 137-53. PMID 18415030 DOI: 10.1007/S12026-008-8017-1 |
0.342 |
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| 2008 |
Breen M, Modiano JF. Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans--man and his best friend share more than companionship. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 16: 145-54. PMID 18293109 DOI: 10.1007/S10577-007-1212-4 |
0.413 |
|
| 2007 |
Fosmire SP, Thomas R, Jubala CM, Wojcieszyn JW, Valli VE, Getzy DM, Smith TL, Gardner LA, Ritt MG, Bell JS, Freeman KP, Greenfield BE, Lana SE, Kisseberth WC, Helfand SC, ... ... Modiano JF, et al. Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma. Veterinary Pathology. 44: 467-78. PMID 17606508 DOI: 10.1354/Vp.44-4-467 |
0.432 |
|
| 2007 |
Lin PY, Fosmire SP, Park SH, Park JY, Baksh S, Modiano JF, Weiss RH. Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance. Molecular Cancer. 6: 16. PMID 17300726 DOI: 10.1186/1476-4598-6-16 |
0.404 |
|
| 2006 |
Lamerato-Kozicki AR, Helm KM, Jubala CM, Cutter GC, Modiano JF. Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation. Experimental Hematology. 34: 870-8. PMID 16797414 DOI: 10.1016/J.Exphem.2006.04.013 |
0.353 |
|
| 2006 |
Modiano JF, Breen M, Avery AC, London CA. 22 Breed-specific Canine Lymphoproliferative Diseases Cold Spring Harbor Monograph Archive. 44: 439-450. DOI: 10.1101/087969781.44.439 |
0.462 |
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| 2005 |
Thomas R, Scott A, Langford CF, Fosmire SP, Jubala CM, Lorentzen TD, Hitte C, Karlsson EK, Kirkness E, Ostrander EA, Galibert F, Lindblad-Toh K, Modiano JF, Breen M. Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors. Genome Research. 15: 1831-7. PMID 16339382 DOI: 10.1101/Gr.3825705 |
0.362 |
|
| 2005 |
Dickerson EB, Thomas R, Fosmire SP, Lamerato-Kozicki AR, Bianco SR, Wojcieszyn JW, Breen M, Helfand SC, Modiano JF. Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma. Veterinary Pathology. 42: 618-32. PMID 16145208 DOI: 10.1354/Vp.42-5-618 |
0.316 |
|
| 2005 |
Jubala CM, Wojcieszyn JW, Valli VE, Getzy DM, Fosmire SP, Coffey D, Bellgrau D, Modiano JF. CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma. Veterinary Pathology. 42: 468-76. PMID 16006606 DOI: 10.1354/Vp.42-4-468 |
0.366 |
|
| 2005 |
Modiano JF, Breen M, Burnett RC, Parker HG, Inusah S, Thomas R, Avery PR, Lindblad-Toh K, Ostrander EA, Cutter GC, Avery AC. Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk. Cancer Research. 65: 5654-61. PMID 15994938 DOI: 10.1158/0008-5472.Can-04-4613 |
0.39 |
|
| 2004 |
Frazer-Abel AA, Baksh S, Fosmire SP, Willis D, Pierce AM, Meylemans H, Linthicum DS, Burakoff SJ, Coons T, Bellgrau D, Modiano JF. Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells. The Journal of Pharmacology and Experimental Therapeutics. 311: 758-69. PMID 15231866 DOI: 10.1124/Jpet.104.070060 |
0.362 |
|
| 2004 |
Modiano JF, Sun J, Lang J, Vacano G, Patterson D, Chan D, Franzusoff A, Gianani R, Meech SJ, Duke R, Bellgrau D. Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells. Clinical Immunology (Orlando, Fla.). 112: 54-65. PMID 15207782 DOI: 10.1016/J.Clim.2004.03.011 |
0.395 |
|
| 2004 |
Fosmire SP, Dickerson EB, Scott AM, Bianco SR, Pettengill MJ, Meylemans H, Padilla M, Frazer-Abel AA, Akhtar N, Getzy DM, Wojcieszyn J, Breen M, Helfand SC, Modiano JF. Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 562-72. PMID 15064773 DOI: 10.1038/Labinvest.3700080 |
0.415 |
|
| 2003 |
Bianco SR, Sun J, Fosmire SP, Hance K, Padilla ML, Ritt MG, Getzy DM, Duke RC, Withrow SJ, Lana S, Matthiesen DT, Dow SW, Bellgrau D, Cutter GR, Helfand SC, ... Modiano JF, et al. Enhancing antimelanoma immune responses through apoptosis. Cancer Gene Therapy. 10: 726-36. PMID 12944992 DOI: 10.1038/Sj.Cgt.7700625 |
0.435 |
|
| 2003 |
Khare S, Banai Y, Gokulan K, Smith R, Linthicum DS, Modiano JF. Early changes in metabolism of leukemic cell lines upon induction of apoptosis by cytotoxic drugs. European Journal of Pharmacology. 465: 23-30. PMID 12650829 DOI: 10.1016/S0014-2999(03)01425-0 |
0.322 |
|
| 2003 |
Burnett RC, Vernau W, Modiano JF, Olver CS, Moore PF, Avery AC. Diagnosis of canine lymphoid neoplasia using clonal rearrangements of antigen receptor genes. Veterinary Pathology. 40: 32-41. PMID 12627711 DOI: 10.1354/Vp.40-1-32 |
0.397 |
|
| 2003 |
Koenig A, Bianco SR, Fosmire S, Wojcieszyn J, Modiano JF. Expression and significance of p53, rb, p21/waf-1, p16/ink-4a, and PTEN tumor suppressors in canine melanoma. Veterinary Pathology. 39: 458-72. PMID 12126149 DOI: 10.1354/Vp.39-4-458 |
0.427 |
|
| 2002 |
Baksh S, Widlund HR, Frazer-Abel AA, Du J, Fosmire S, Fisher DE, DeCaprio JA, Modiano JF, Burakoff SJ. NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Molecular Cell. 10: 1071-81. PMID 12453415 DOI: 10.1016/S1097-2765(02)00701-3 |
0.34 |
|
| 2002 |
Fernandes PJ, Modiano JF, Wojcieszyn J, Thomas JS, Benson PA, Smith R, Avery AC, Burnett RC, Boone LI, Johnson MC, Pierce KR. Use of the Cell-Dyn 3500 to predict leukemic cell lineage in peripheral blood of dogs and cats. Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology. 31: 167-82. PMID 12447779 DOI: 10.1111/J.1939-165X.2002.Tb00298.X |
0.357 |
|
| 2002 |
Dickerson EB, Fosmire S, Padilla ML, Modiano JF, Helfand SC. Potential to target dysregulated interleukin-2 receptor expression in canine lymphoid and hematopoietic malignancies as a model for human cancer. Journal of Immunotherapy (Hagerstown, Md. : 1997). 25: 36-45. PMID 11924909 DOI: 10.1097/00002371-200201000-00004 |
0.389 |
|
| 2002 |
Dickerson EB, Fosmire S, Padilla ML, Modiano JF, Helfand SC. Erratum: Potential to target dysregulated interleukin-2 receptor expression in canine lymphoid and hematopoietic malignancies as a model for human cancer (Journal of Immunotheraphy (2002) 25 (36-45)) Journal of Immunotherapy. 25. DOI: 10.1097/00002371-200203000-00007 |
0.351 |
|
| 2001 |
Koenig A, Wojcieszyn J, Weeks BR, Modiano JF. Expression of S100a, vimentin, NSE, and melan A/MART-1 in seven canine melanoma cells lines and twenty-nine retrospective cases of canine melanoma. Veterinary Pathology. 38: 427-35. PMID 11467477 DOI: 10.1354/Vp.38-4-427 |
0.441 |
|
| 2000 |
Modiano JF, Mayor J, Ball C, Fuentes MK, Linthicum DS. CDK4 expression and activity are required for cytokine responsiveness in T cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 6693-702. PMID 11120786 DOI: 10.4049/Jimmunol.165.12.6693 |
0.396 |
|
| 2000 |
Ritt MG, Mayor J, Wojcieszyn J, Smith R, Barton CL, Modiano JF. Sustained nuclear localization of p21/WAF-1 upon growth arrest induced by contact inhibition. Cancer Letters. 158: 73-84. PMID 10940512 DOI: 10.1016/S0304-3835(00)00507-3 |
0.381 |
|
| 1999 |
Modiano JF, Mayor J, Ball C, Chitko-McKown CG, Sakata N, Domenico-Hahn J, Lucas JJ, Gelfand EW. Quantitative and qualitative signals determine T-cell cycle entry and progression. Cellular Immunology. 197: 19-29. PMID 10555992 DOI: 10.1006/Cimm.1999.1563 |
0.402 |
|
| 1999 |
Modiano JF, Ritt MG, Wojcieszyn J, Smith R. Growth arrest of melanoma cells is differentially regulated by contact inhibition and serum deprivation. Dna and Cell Biology. 18: 357-67. PMID 10360837 DOI: 10.1089/104454999315259 |
0.378 |
|
| 1999 |
Modiano JF, Ritt MG, Wojcieszyn J. The Molecular Basis of Canine Melanoma: Pathogenesis and Trends in Diagnosis and Therapy Journal of Veterinary Internal Medicine. 13: 163-174. DOI: 10.1111/J.1939-1676.1999.Tb02173.X |
0.416 |
|
| 1998 |
Modiano JF, Smith R, Wojcieszyn J, Thomas JS, Rosenbaum BA, Ball C, Nicholds EA, Anthony MA, Barton CL. The use of cytochemistry, immunophenotyping, flow cytometry, and in vitro differentiation to determine the ontogeny of a canine monoblastic leukemia. Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology. 27: 40-49. PMID 12075547 DOI: 10.1111/J.1939-165X.1998.Tb01014.X |
0.411 |
|
| 1998 |
Ritt MG, Wojcieszyn J, Modiano JF. Functional loss of p21/Waf-1 in a case of benign canine multicentric melanoma. Veterinary Pathology. 35: 94-101. PMID 9539362 DOI: 10.1177/030098589803500202 |
0.358 |
|
| 1997 |
Chitko-McKown CG, Modiano JF. Clues to immune function and oncogenesis provided by events that activate the cell cycle machinery in normal human T cells. Journal of Leukocyte Biology. 62: 430-7. PMID 9335311 DOI: 10.1002/Jlb.62.4.430 |
0.419 |
|
| 1997 |
Modiano JF, Amran D, Lack G, Bradley K, Ball C, Domenico J, Gelfand EW. Posttranscriptional regulation of T-cell IL-2 production by human pooled immunoglobin. Clinical Immunology and Immunopathology. 83: 77-85. PMID 9073539 DOI: 10.1006/Clin.1997.4329 |
0.316 |
|
| 1995 |
Modiano JF, Getzy DM, Akol KG, Van Winkle TJ, Cockerell GL. Retrovirus-like activity in an immunosuppressed dog: pathological and immunological findings. Journal of Comparative Pathology. 112: 165-83. PMID 7539463 DOI: 10.1016/S0021-9975(05)80059-3 |
0.354 |
|
| 1995 |
Modiano JF, Domenico J, Szepesi A, Terada N, Lucas JJ, Gelfand EW. Symmetry of the activation of cyclin-dependent kinases in mitogen and growth factor-stimulated T lymphocytes. Annals of the New York Academy of Sciences. 766: 134-48. PMID 7486650 DOI: 10.1111/J.1749-6632.1995.Tb26657.X |
0.349 |
|
| 1995 |
Helfand S, Modiano J, Moore P, Soergel S, MacWilliams P, Dubielzig R, Hank J, Gelfand E, Sondel P. Functional interleukin-2 receptors are expressed on natural killer-like leukemic cells from a dog with cutaneous lymphoma Blood. 86: 636-645. DOI: 10.1182/Blood.V86.2.636.Bloodjournal862636 |
0.4 |
|
| 1994 |
Helfand SC, Soergel SA, Modiano JF, Hank JA, Sondel PM. Induction of lymphokine-activated killer (LAK) activity in canine lymphocytes with low dose human recombinant interleukin-2 in vitro. Cancer Biotherapy. 9: 237-44. PMID 7820185 DOI: 10.1089/Cbr.1994.9.237 |
0.397 |
|
| 1992 |
Helfand SC, Modiano JF, Nowell PC. Immunophysiological studies of interleukin-2 and canine lymphocytes. Veterinary Immunology and Immunopathology. 33: 1-16. PMID 1632072 DOI: 10.1016/0165-2427(92)90030-T |
0.404 |
|
| 1991 |
Modiano JF, Kokai Y, Weiner DB, Pykett MJ, Nowell PC, Lyttle CR. Progesterone augments proliferation induced by epidermal growth factor in a feline mammary adenocarcinoma cell line. Journal of Cellular Biochemistry. 45: 196-206. PMID 2055947 DOI: 10.1002/Jcb.240450211 |
0.325 |
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