Jaime F. Modiano - Publications

Comparative and Molecular Biosciences University of Minnesota, Twin Cities, Minneapolis, MN 
Molecular Biology, Bioinformatics Biology, Veterinary Science Biology, Oncology

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kim JH, Megquier K, Thomas R, Sarver AL, Song JM, Kim YT, Cheng N, Schulte AJ, Linden MA, Murugan P, Oseth L, Forster CL, Elvers I, Swofford R, Turner-Maier J, ... ... Modiano JF, et al. Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions. Molecular Cancer Research : McR. PMID 33649193 DOI: 10.1158/1541-7786.MCR-20-0937  0.32
2020 Mills LJ, Scott MC, Shah P, Cunanan AR, Deshpande A, Auch B, Curtin B, Beckman KB, Spector LG, Sarver AL, Subramanian S, Richmond TA, Modiano JF. Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma. Bone. 115716. PMID 33127576 DOI: 10.1016/j.bone.2020.115716  0.32
2020 Oh F, Modiano JF, Bachanova V, Vallera DA. Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors. Biomolecules. 10. PMID 32630411 DOI: 10.3390/biom10060956  0.44
2020 Borgatti A, Fieberg A, Winter AL, Stuebner K, Taras E, Todhunter D, Masyr A, Rendhal A, Vallera DA, Koopmeiners JS, Modiano JF. Impact of Repeated Cycles of EGF Bispecific Angiotoxin (eBAT) Administered at a Reduced Interval from Doxorubicin Chemotherapy in Dogs with Splenic Hemangiosarcoma. Veterinary and Comparative Oncology. PMID 32187827 DOI: 10.1111/Vco.12590  0.44
2019 Langsten KL, Kim JH, Sarver AL, Dewhirst M, Modiano JF. Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment. Frontiers in Oncology. 9: 1185. PMID 31788448 DOI: 10.3389/Fonc.2019.01185  0.32
2019 Megquier K, Turner-Maier J, Swofford R, Kim JH, Sarver AL, Wang C, Sakthikumar S, Johnson J, Koltookian M, Lewellen M, Scott MC, Graef AJ, Borst L, Tonomura N, Alfoldi J, ... ... Modiano JF, et al. Comparative genomics reveals shared mutational landscape in canine hemangiosarcoma and human angiosarcoma. Molecular Cancer Research : McR. PMID 31570656 DOI: 10.1158/1541-7786.Mcr-19-0221  0.32
2019 Makielski KM, Mills LJ, Sarver AL, Henson MS, Spector LG, Naik S, Modiano JF. Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review. Veterinary Sciences. 6. PMID 31130627 DOI: 10.3390/Vetsci6020048  0.32
2018 Kim JH, Frantz AM, Anderson KL, Graef AJ, Scott MC, Robinson S, Sharkey LC, O'Brien TD, Dickerson EB, Modiano JF. Corrigendum to: "Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment" [Exp. Cell. Res. 2014 15 323(1) 155-64]. Experimental Cell Research. PMID 30017210 DOI: 10.1016/j.yexcr.2018.07.012  0.44
2017 Kim JH, Frantz AM, Sarver AL, Gorden Klukas BH, Lewellen M, O'Brien TD, Dickerson EB, Modiano JF. Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers. Veterinary and Comparative Oncology. PMID 29152836 DOI: 10.1111/Vco.12368  0.44
2017 Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma. Cancer Research. PMID 29066513 DOI: 10.1158/0008-5472.Can-17-0576  0.32
2017 Borgatti A, Winter AL, Stuebner K, Scott R, Ober CP, Anderson KL, Feeney DA, Vallera DA, Koopmeiners JS, Modiano JF, Froelich J. Evaluation of 18-F-fluoro-2-deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) as a staging and monitoring tool for dogs with stage-2 splenic hemangiosarcoma - A pilot study. Plos One. 12: e0172651. PMID 28222142 DOI: 10.1371/Journal.Pone.0172651  0.44
2017 Borgatti A, Koopmeiners JS, Sarver AL, Winter AL, Stuebner K, Todhunter D, Rizzardi AE, Henricksen JC, Schmechel S, Forster CL, Kim JH, Froelich J, Walz J, Henson MS, Breen M, ... ... Modiano JF, et al. Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR. Molecular Cancer Therapeutics. PMID 28193671 DOI: 10.1158/1535-7163.Mct-16-0637  0.44
2016 Im KS, Kim JH, Graef AJ, Cornax I, Seelig DM, O'Sullivan MG, Kovi RC, Modiano JF. Establishment of a Patient-Derived Xenograft of Canine Enteropathy-Associated T-Cell Lymphoma, Large Cell Type. Journal of Comparative Pathology. PMID 28011041 DOI: 10.1016/j.jcpa.2016.11.271  0.32
2016 Seelig DM, Ito D, Forster CL, Yoon UA, Breen M, Burns LJ, Bachanova V, Lindblad-Toh K, O'Brien TD, Schmechel SC, Rizzardi AE, Modiano JF, Linden MA. Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies. Leukemia & Lymphoma. 1-9. PMID 27931134 DOI: 10.1080/10428194.2016.1260122  0.32
2016 Weiskopf K, Anderson KL, Ito D, Schnorr PJ, Tomiyasu H, Ring AM, Bloink K, Efe J, Rue S, Lowery D, Barkal A, Prohaska S, McKenna KM, Cornax I, O'Brien TD, ... ... Modiano JF, et al. Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20. Cancer Immunology Research. PMID 27856424 DOI: 10.1158/2326-6066.Cir-16-0105  0.32
2016 Trott JF, Kim J, Aboud OA, Wettersten H, Stewart B, Berryhill G, Uzal F, Hovey RC, Chen CH, Anderson K, Graef A, Sarver AL, Modiano JF, Weiss RH. Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. Oncotarget. PMID 27572319 DOI: 10.18632/Oncotarget.11658  0.32
2016 Kim JH, Furrow E, Ritt MG, Utz PJ, Robinson WH, Yu L, Eckert A, Stuebner K, O'Brien TD, Steinman L, Modiano JF. Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes. Plos One. 11: e0152397. PMID 27031512 DOI: 10.1371/Journal.Pone.0152397  0.44
2015 Kim JH, Graef AJ, Dickerson EB, Modiano JF. Pathobiology of Hemangiosarcoma in Dogs: Research Advances and Future Perspectives. Veterinary Sciences. 2: 388-405. PMID 29061949 DOI: 10.3390/vetsci2040388  0.44
2015 Ritt MG, Lindborg BA, O'Brien TD, Bisignano J, Modiano JF. Stimulation with Concanavalin-A Induces IL-17 Production by Canine Peripheral T Cells. Veterinary Sciences. 2: 43-51. PMID 29061930 DOI: 10.3390/vetsci2020043  0.32
2015 Ito D, Childress M, Mason N, Winter A, O'Brien T, Henson M, Borgatti A, Lewellen M, Krick E, Stewart J, Lahrman S, Leary J, Seelig D, Koopmeiners J, Ruetz S, ... Modiano J, et al. A double blinded, placebo-controlled pilot study to examine reduction of CD34 (+)/CD117 (+)/CD133 (+) lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma. F1000research. 4: 42. PMID 28357033 DOI: 10.12688/f1000research.6055.3  0.32
2015 Scott MC, Sarver AL, Tomiyasu H, Cornax I, Van Etten J, Varshney J, O'Sullivan MG, Subramanian S, Modiano JF. Aberrant RB-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma. The Journal of Biological Chemistry. PMID 26378234 DOI: 10.1074/Jbc.M115.679696  0.44
2015 Elvers I, Turner-Maier J, Swofford R, Koltookian M, Johnson J, Stewart C, Zhang CZ, Schumacher SE, Beroukhim R, Rosenberg M, Thomas R, Mauceli E, Getz G, di Palma F, Modiano JF, et al. Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background. Genome Research. PMID 26377837 DOI: 10.1101/Gr.194449.115  0.44
2015 Im KS, Graef AJ, Breen M, Lindblad-Toh K, Modiano JF, Kim JH. Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma. Veterinary and Comparative Oncology. PMID 26337509 DOI: 10.1111/vco.12165  0.32
2015 Modiano JF, Lindborg BA, McElmurry RT, Lewellen M, Forster CL, Zamora EA, Schaack J, Bellgrau D, O'Brien TD, Tolar J. Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment. Cancer Immunology, Immunotherapy : Cii. 64: 1449-60. PMID 26250807 DOI: 10.1007/s00262-015-1749-6  0.44
2015 Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, ... Modiano JF, et al. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. Nature Genetics. 47: 615-24. PMID 25961939 DOI: 10.1038/Ng.3293  0.44
2015 Tonomura N, Elvers I, Thomas R, Megquier K, Turner-Maier J, Howald C, Sarver AL, Swofford R, Frantz AM, Ito D, Mauceli E, Arendt M, Noh HJ, Koltookian M, Biagi T, ... ... Modiano JF, et al. Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. Plos Genetics. 11: e1004922. PMID 25642983 DOI: 10.1371/Journal.Pgen.1004922  0.44
2015 Ito D, Brewer S, Modiano JF, Beall MJ. Development of a novel anti-canine CD20 monoclonal antibody with diagnostic and therapeutic potential. Leukemia & Lymphoma. 56: 219-25. PMID 24724777 DOI: 10.3109/10428194.2014.914193  0.44
2015 Cannon CM, Pozniak J, Scott MC, Ito D, Gorden BH, Graef AJ, Modiano JF. Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors. Veterinary and Comparative Oncology. 13: 48-59. PMID 23410058 DOI: 10.1111/vco.12018  0.44
2014 May SL, Zhou Q, Lewellen M, Carter CM, Coffey D, Highfill SL, Bucher CM, Matise I, Morse HC, O'Sullivan MG, Schutten M, Johnson C, Bellgrau D, Blazar BR, Modiano JF. Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis. Plos One. 9: e100629. PMID 24945807 DOI: 10.1371/journal.pone.0100629  0.44
2014 Ito D, Frantz AM, Modiano JF. Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications. Veterinary Immunology and Immunopathology. 159: 192-201. PMID 24642290 DOI: 10.1016/j.vetimm.2014.02.016  0.44
2014 Kim JH, Frantz AM, Anderson KL, Graef AJ, Scott MC, Robinson S, Sharkey LC, O'Brien TD, Dickerson EB, Modiano JF. Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment. Experimental Cell Research. 323: 155-64. PMID 24582862 DOI: 10.1016/j.yexcr.2014.02.020  0.44
2014 Gorden BH, Kim JH, Sarver AL, Frantz AM, Breen M, Lindblad-Toh K, O'Brien TD, Sharkey LC, Modiano JF, Dickerson EB. Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization. The American Journal of Pathology. 184: 985-95. PMID 24525151 DOI: 10.1016/J.Ajpath.2013.12.025  0.44
2014 London CA, Bernabe LF, Barnard S, Kisseberth WC, Borgatti A, Henson M, Wilson H, Jensen K, Ito D, Modiano JF, Bear MD, Pennell ML, Saint-Martin JR, McCauley D, Kauffman M, et al. Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study. Plos One. 9: e87585. PMID 24503695 DOI: 10.1371/journal.pone.0087585  0.44
2014 Koopmeiners JS, Modiano J. A Bayesian adaptive Phase I-II clinical trial for evaluating efficacy and toxicity with delayed outcomes. Clinical Trials (London, England). 11: 38-48. PMID 24082004 DOI: 10.1177/1740774513500589  0.44
2014 Borgatti A, Duckett M, Charles S, Modiano JF. Binding of VEGF-A to canine cancer cells with preferential expression of VEGFR1 Veterinary World. 7: 1-6. DOI: 10.14202/vetworld.2014.1-6  0.44
2013 Karlsson EK, Sigurdsson S, Ivansson E, Thomas R, Elvers I, Wright J, Howald C, Tonomura N, Perloski M, Swofford R, Biagi T, Fryc S, Anderson N, Courtay-Cahen C, Youell L, ... ... Modiano JF, et al. Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B. Genome Biology. 14: R132. PMID 24330828 DOI: 10.1186/Gb-2013-14-12-R132  0.44
2013 Feeney DA, Sharkey LC, Steward SM, Bahr KL, Henson MS, Ito D, O'Brien TD, Jessen CR, Husbands BD, Borgatti A, Modiano J. Applicability of 3T body MRI in assessment of nonfocal bone marrow involvement of hematopoietic neoplasia in dogs. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 27: 1165-71. PMID 23888934 DOI: 10.1111/jvim.12151  0.44
2013 Michael HT, Ito D, McCullar V, Zhang B, Miller JS, Modiano JF. Isolation and characterization of canine natural killer cells. Veterinary Immunology and Immunopathology. 155: 211-7. PMID 23876304 DOI: 10.1016/j.vetimm.2013.06.013  0.44
2013 Culver S, Ito D, Borst L, Bell JS, Modiano JF, Breen M. Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy. Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology. 42: 314-22. PMID 23800034 DOI: 10.1111/vcp.12055  0.44
2013 Feeney DA, Sharkey LC, Steward SM, Bahr KL, Henson MS, Ito D, O'Brien TD, Jessen CR, Husbands BD, Borgatti A, Modiano JF. Parenchymal signal intensity in 3-T body MRI of dogs with hematopoietic neoplasia. Comparative Medicine. 63: 174-82. PMID 23582424  0.44
2013 Stiles JM, Amaya C, Rains S, Diaz D, Pham R, Battiste J, Modiano JF, Kokta V, Boucheron LE, Mitchell DC, Bryan BA. Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma. Plos One. 8: e60021. PMID 23555867 DOI: 10.1371/journal.pone.0060021  0.44
2013 Schappa JT, Frantz AM, Gorden BH, Dickerson EB, Vallera DA, Modiano JF. Hemangiosarcoma and its cancer stem cell subpopulation are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors. International Journal of Cancer. 133: 1936-44. PMID 23553371 DOI: 10.1002/ijc.28187  0.44
2013 Wells JW, Evans CH, Scott MC, Rütgen BC, O'Brien TD, Modiano JF, Cvetkovic G, Tepic S. Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation Plos One. 8. PMID 23365669 DOI: 10.1371/journal.pone.0054464  0.44
2013 Sarver AL, Thayanithy V, Scott MC, Cleton-Jansen AM, Hogendoorn PC, Modiano JF, Subramanian S. MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma. Orphanet Journal of Rare Diseases. 8: 7. PMID 23311495 DOI: 10.1186/1750-1172-8-7  0.44
2013 Frantz AM, Sarver AL, Ito D, Phang TL, Karimpour-Fard A, Scott MC, Valli VE, Lindblad-Toh K, Burgess KE, Husbands BD, Henson MS, Borgatti A, Kisseberth WC, Hunter LE, Breen M, ... ... Modiano JF, et al. Molecular profiling reveals prognostically significant subtypes of canine lymphoma. Veterinary Pathology. 50: 693-703. PMID 23125145 DOI: 10.1177/0300985812465325  0.44
2012 Thayanithy V, Park C, Sarver AL, Kartha RV, Korpela DM, Graef AJ, Steer CJ, Modiano JF, Subramanian S. Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. Plos One. 7: e43720. PMID 22957032 DOI: 10.1371/Journal.Pone.0043720  0.44
2012 Modiano JF, Bellgrau D, Cutter GR, Lana SE, Ehrhart NP, Ehrhart E, Wilke VL, Charles JB, Munson S, Scott MC, Pozniak J, Carlson CS, Schaack J, Duke RC. Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2234-43. PMID 22850679 DOI: 10.1038/Mt.2012.149  0.44
2012 Larson G, Karlsson EK, Perri A, Webster MT, Ho SY, Peters J, Stahl PW, Piper PJ, Lingaas F, Fredholm M, Comstock KE, Modiano JF, Schelling C, Agoulnik AI, Leegwater PA, et al. Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proceedings of the National Academy of Sciences of the United States of America. 109: 8878-83. PMID 22615366 DOI: 10.1073/Pnas.1203005109  0.44
2012 Ito D, Frantz AM, Williams C, Thomas R, Burnett RC, Avery AC, Breen M, Mason NJ, O'Brien TD, Modiano JF. CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies. Leukemia & Lymphoma. 53: 1390-8. PMID 22229753 DOI: 10.3109/10428194.2011.654337  0.44
2012 Thayanithy V, Sarver AL, Kartha RV, Li L, Angstadt AY, Breen M, Steer CJ, Modiano JF, Subramanian S. Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. Bone. 50: 171-81. PMID 22037351 DOI: 10.1016/J.Bone.2011.10.012  0.44
2011 Murphy SE, von Weymarn LB, Schutten MM, Kassie F, Modiano JF. Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis. Cancer Prevention Research (Philadelphia, Pa.). 4: 1752-60. PMID 22027684 DOI: 10.1158/1940-6207.CAPR-11-0366  0.44
2011 Angstadt AY, Motsinger-Reif A, Thomas R, Kisseberth WC, Guillermo Couto C, Duval DL, Nielsen DM, Modiano JF, Breen M. Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart. Genes, Chromosomes & Cancer. 50: 859-74. PMID 21837709 DOI: 10.1002/Gcc.20908  0.44
2011 Ito D, Endicott MM, Jubala CM, Helm KM, Burnett RC, Husbands BD, Borgatti A, Henson MS, Burgess KE, Bell JS, Kisseberth WC, Valli VE, Cutter GR, Avery AC, Hahn KA, ... ... Modiano JF, et al. A tumor-related lymphoid progenitor population supports hierarchical tumor organization in canine B-cell lymphoma. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 25: 890-6. PMID 21777289 DOI: 10.1111/j.1939-1676.2011.0756.x  0.44
2011 Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone. 49: 356-67. PMID 21621658 DOI: 10.1016/J.Bone.2011.05.008  0.44
2011 Henson MS, Curtsinger JM, Larson VS, Klausner JS, Modiano JF, Mescher MF, Miller JS. Immunotherapy with autologous tumour antigen-coated microbeads (large multivalent immunogen), IL-2 and GM-CSF in dogs with spontaneous B-cell lymphoma. Veterinary and Comparative Oncology. 9: 95-105. PMID 21569195 DOI: 10.1111/J.1476-5829.2010.00234.X  0.44
2010 Ito D, O'Brien TD, Modiano JF. Exclusion of cytoplasmic fragments in flow cytometric analysis of lymph node samples from dogs with lymphoma using membrane-permeable violet laser-excitable DNA-binding fluorescent dye (DyeCycle Violet) Veterinary Clinical Pathology. 39: 494-498. PMID 21198735 DOI: 10.1111/j.1939-165X.2010.00252.x  0.44
2010 Husbands BD, McNiel EA, Modiano JF. Initial evaluation of safety of wide-field irradiation in the treatment of hematopoietic neoplasia in the cat. Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 51: 688-96. PMID 21158248 DOI: 10.1111/j.1740-8261.2010.01728.x  0.44
2010 Tamburini BA, Phang TL, Fosmire SP, Scott MC, Trapp SC, Duckett MM, Robinson SR, Slansky JE, Sharkey LC, Cutter GR, Wojcieszyn JW, Bellgrau D, Gemmill RM, Hunter LE, Modiano JF. Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. Bmc Cancer. 10: 619. PMID 21062482 DOI: 10.1186/1471-2407-10-619  0.44
2010 Ishimaru T, Lau J, Jackson AL, Modiano JF, Weiss RH. Pharmacological inhibition of cyclin dependent kinases causes p53 dependent apoptosis in renal cell carcinoma. The Journal of Urology. 184: 2143-9. PMID 20850841 DOI: 10.1016/j.juro.2010.06.088  0.44
2010 Oloris SC, Frazer-Abel AA, Jubala CM, Fosmire SP, Helm KM, Robinson SR, Korpela DM, Duckett MM, Baksh S, Modiano JF. Nicotine-mediated signals modulate cell death and survival of T lymphocytes. Toxicology and Applied Pharmacology. 242: 299-309. PMID 19896492 DOI: 10.1016/j.taap.2009.10.020  0.44
2009 Tamburini BA, Trapp S, Phang TL, Schappa JT, Hunter LE, Modiano JF. Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed. Plos One. 4: e5549. PMID 19461996 DOI: 10.1371/Journal.Pone.0005549  0.44
2009 Willoughby JA, Sundar SN, Cheung M, Tin AS, Modiano J, Firestone GL. Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression. The Journal of Biological Chemistry. 284: 2203-13. PMID 19017637 DOI: 10.1074/Jbc.M804491200  0.44
2007 Fosmire SP, Thomas R, Jubala CM, Wojcieszyn JW, Valli VE, Getzy DM, Smith TL, Gardner LA, Ritt MG, Bell JS, Freeman KP, Greenfield BE, Lana SE, Kisseberth WC, Helfand SC, ... ... Modiano JF, et al. Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma. Veterinary Pathology. 44: 467-78. PMID 17606508 DOI: 10.1354/vp.44-4-467  0.44
2005 Thomas R, Scott A, Langford CF, Fosmire SP, Jubala CM, Lorentzen TD, Hitte C, Karlsson EK, Kirkness E, Ostrander EA, Galibert F, Lindblad-Toh K, Modiano JF, Breen M. Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors. Genome Research. 15: 1831-7. PMID 16339382 DOI: 10.1101/gr.3825705  0.44
2005 Dickerson EB, Thomas R, Fosmire SP, Lamerato-Kozicki AR, Bianco SR, Wojcieszyn JW, Breen M, Helfand SC, Modiano JF. Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma. Veterinary Pathology. 42: 618-32. PMID 16145208 DOI: 10.1354/vp.42-5-618  0.44
2004 Frazer-Abel AA, Baksh S, Fosmire SP, Willis D, Pierce AM, Meylemans H, Linthicum DS, Burakoff SJ, Coons T, Bellgrau D, Modiano JF. Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells. The Journal of Pharmacology and Experimental Therapeutics. 311: 758-69. PMID 15231866 DOI: 10.1124/jpet.104.070060  0.44
2004 Fosmire SP, Dickerson EB, Scott AM, Bianco SR, Pettengill MJ, Meylemans H, Padilla M, Frazer-Abel AA, Akhtar N, Getzy DM, Wojcieszyn J, Breen M, Helfand SC, Modiano JF. Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 562-72. PMID 15064773 DOI: 10.1038/labinvest.3700080  0.44
2003 Bianco SR, Sun J, Fosmire SP, Hance K, Padilla ML, Ritt MG, Getzy DM, Duke RC, Withrow SJ, Lana S, Matthiesen DT, Dow SW, Bellgrau D, Cutter GR, Helfand SC, ... Modiano JF, et al. Enhancing antimelanoma immune responses through apoptosis. Cancer Gene Therapy. 10: 726-36. PMID 12944992 DOI: 10.1038/sj.cgt.7700625  0.44
2002 Baksh S, Widlund HR, Frazer-Abel AA, Du J, Fosmire S, Fisher DE, DeCaprio JA, Modiano JF, Burakoff SJ. NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Molecular Cell. 10: 1071-81. PMID 12453415 DOI: 10.1016/S1097-2765(02)00701-3  0.44
2002 Dickerson EB, Fosmire S, Padilla ML, Modiano JF, Helfand SC. Potential to target dysregulated interleukin-2 receptor expression in canine lymphoid and hematopoietic malignancies as a model for human cancer. Journal of Immunotherapy (Hagerstown, Md. : 1997). 25: 36-45. PMID 11924909 DOI: 10.1097/00002371-200201000-00004  0.44
2000 Ritt MG, Mayor J, Wojcieszyn J, Smith R, Barton CL, Modiano JF. Sustained nuclear localization of p21/WAF-1 upon growth arrest induced by contact inhibition. Cancer Letters. 158: 73-84. PMID 10940512 DOI: 10.1016/S0304-3835(00)00507-3  0.44
1998 Fernandes PJ, Guyer C, Modiano JF. Mammary mass aspirate from a Yorkshire terrier. Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology. 27: 79. PMID 12075542  0.44
1996 Walton RM, Modiano JF, Thrall MA, Wheeler SL. Bone marrow cytological findings in 4 dogs and a cat with hemophagocytic syndrome. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 10: 7-14. PMID 8965270 DOI: 10.1111/j.1939-1676.1996.tb02017.x  0.44
1994 Helfand SC, Soergel SA, Modiano JF, Hank JA, Sondel PM. Induction of lymphokine-activated killer (LAK) activity in canine lymphocytes with low dose human recombinant interleukin-2 in vitro. Cancer Biotherapy. 9: 237-44. PMID 7820185 DOI: 10.1089/cbr.1994.9.237  0.44
1992 Helfand SC, Modiano JF, Nowell PC. Immunophysiological studies of interleukin-2 and canine lymphocytes. Veterinary Immunology and Immunopathology. 33: 1-16. PMID 1632072 DOI: 10.1016/0165-2427(92)90030-T  0.44
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