Chuanshu Huang - Publications

Affiliations: 
Environmental Health Science New York University, New York, NY, United States 
Area:
Environmental Health, Molecular Biology, Oncology

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yan H, Ren S, Lin Q, Yu Y, Chen C, Hua X, Jin H, Lu Y, Zhang H, Xie Q, Huang C, Huang H. Inhibition of UBE2N-dependent CDK6 protein degradation by miR-934 promotes human bladder cancer cell growth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900499RR. PMID 31373842 DOI: 10.1096/fj.201900499RR  0.68
2019 Hua X, Huang M, Deng X, Xu J, Luo Y, Xie Q, Xu J, Tian Z, Li J, Zhu J, Huang C, Zhao QS, Huang H, Huang C. The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein. Cell Death and Differentiation. PMID 31243344 DOI: 10.1038/s41418-019-0377-7  0.68
2019 Jin H, Xue L, Mo L, Zhang D, Guo X, Xu J, Li J, Peng M, Zhao X, Zhong M, Xu D, Wu XR, Huang H, Huang C. Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer. Cell Adhesion & Migration. 13: 236-248. PMID 31240993 DOI: 10.1080/19336918.2019.1633851  0.68
2019 Luo Y, Tian Z, Hua X, Huang M, Xu J, Li J, Huang H, Cohen M, Huang C. Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression. Cellular and Molecular Life Sciences : Cmls. PMID 31222373 DOI: 10.1007/s00018-019-03185-3  0.68
2019 Tian Z, Luo Y, Zhu J, Hua X, Xu J, Huang C, Jin H, Huang H, Huang C. Transcriptionally elevation of miR-494 by new ChlA-F compound via a HuR/JunB axis inhibits human bladder cancer cell invasion. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. PMID 31167152 DOI: 10.1016/j.bbagrm.2019.05.007  0.68
2019 Sun W, Li S, Yu Y, Jin H, Xie Q, Hua X, Wang S, Tian Z, Zhang H, Jiang G, Huang C, Huang H. MicroRNA-3648 Is Upregulated to Suppress TCF21, Resulting in Promotion of Invasion and Metastasis of Human Bladder Cancer. Molecular Therapy. Nucleic Acids. 16: 519-530. PMID 31071528 DOI: 10.1016/j.omtn.2019.04.006  0.68
2019 Zhu J, Tian Z, Li Y, Hua X, Zhang D, Li J, Jin H, Xu J, Chen W, Niu B, Wu XR, Comincini S, Huang H, Huang C. ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1801927. PMID 31016112 DOI: 10.1002/advs.201801927  0.68
2019 Xie Q, Chen C, Li H, Xu J, Wu L, Yu Y, Ren S, Li H, Hua X, Yan H, Rao D, Zhang H, Jin H, Huang H, Huang C. miR-3687 Overexpression Promotes Bladder Cancer Cell Growth by Inhibiting the Negative Effect of FOXP1 on Cyclin E2 Transcription. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30935821 DOI: 10.1016/j.ymthe.2019.03.006  0.68
2019 Zhu J, Li Y, Luo Y, Xu J, Liufu H, Tian Z, Huang C, Li J, Huang C. A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer. Cancers. 11. PMID 30871066 DOI: 10.3390/cancers11030349  0.68
2019 Huang C, Liao X, Jin H, Xie F, Zheng F, Li J, Zhou C, Jiang G, Wu XR, Huang C. MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion. Molecular Therapy. Nucleic Acids. 16: 51-62. PMID 30826633 DOI: 10.1016/j.omtn.2019.01.014  0.68
2019 Peng M, Wang J, Tian Z, Zhang D, Jin H, Liu C, Xu J, Li J, Hua X, Xu J, Huang C, Huang C. Autophagy-Mediated Mir6981 Degradation Exhibits Cdkn1b Promotion of PHLPP1 Protein Translation. Autophagy. PMID 30821592 DOI: 10.1080/15548627.2019.1586254  0.68
2019 Jiang G, Huang C, Liao X, Li J, Wu XR, Zeng F, Huang C. The RING domain in the anti-apoptotic protein XIAP stabilizes c-Myc protein and preserves anchorage-independent growth of bladder cancer cells. The Journal of Biological Chemistry. PMID 30819803 DOI: 10.1074/jbc.RA118.005621  0.68
2019 Zhu J, Huang G, Hua X, Li Y, Yan H, Che X, Tian Z, Liufu H, Huang C, Li J, Xu J, Dai W, Huang H, Huang C. CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells. Oncogene. PMID 30635654 DOI: 10.1038/s41388-018-0664-7  0.68
2018 Guo X, Huang H, Jin H, Xu J, Risal S, Li J, Li X, Yan H, Zeng X, Xue L, Chen C, Huang C. ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion. Molecular Therapy. Nucleic Acids. 12: 337-349. PMID 30195772 DOI: 10.1016/j.omtn.2018.05.017  0.68
2018 Hua X, Xu J, Deng X, Xu J, Li J, Zhu DQ, Zhu J, Jin H, Tian Z, Huang H, Zhao QS, Huang C. New Compound ChlA-F Induces Autophagy-dependent Anti-cancer Effect via Upregulating Sestrin-2 in Human Bladder Cancer. Cancer Letters. PMID 30118841 DOI: 10.1016/j.canlet.2018.08.013  0.68
2018 Li X, Tian Z, Jin H, Xu J, Hua X, Yan H, Liufu H, Wang J, Li J, Zhu J, Huang H, Huang C. Decreased c-Myc mRNA Stability miR-141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Transcription and Bladder Cancer Cell Tumorigenicity. Molecular and Cellular Biology. PMID 30104251 DOI: 10.1128/MCB.00273-18  0.68
2018 Peng M, Wang J, Zhang D, Jin H, Li J, Wu XR, Huang C. PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein. Oncogene. PMID 29930380 DOI: 10.1038/s41388-018-0374-1  0.68
2018 Jin H, Sun W, Zhang Y, Yan H, Liufu H, Wang S, Chen C, Gu J, Hua X, Zhou L, Jiang G, Rao D, Xie Q, Huang H, Huang C. MicroRNA-411 Downregulation Enhances Tumor Growth by Upregulating MLLT11 Expression in Human Bladder Cancer. Molecular Therapy. Nucleic Acids. 11: 312-322. PMID 29858066 DOI: 10.1016/j.omtn.2018.03.003  0.68
2018 Jiang G, Huang C, Li J, Huang H, Wang J, Li Y, Xie F, Jin H, Zhu J, Huang C. Transcriptional and Posttranscriptional Upregulation of p27 Mediates Growth Inhibition of Isorhapontigenin (ISO) on Human Bladder Cancer Cells. Carcinogenesis. PMID 29409027 DOI: 10.1093/carcin/bgy015  0.68
2017 Yu Y, Jin H, Xu J, Gu J, Li X, Xie Q, Huang H, Li J, Tian Z, Jiang G, Chen C, He F, Wu XR, Huang C. XIAP Overexpression Promotes Bladder Cancer Invasion in Vitro and Lung Metastasis in Vivo via Enhancing Nucleolin-Mediated Rho-GDIβ mRNA Stability. International Journal of Cancer. PMID 29250796 DOI: 10.1002/ijc.31223  0.68
2017 Liao X, Huang C, Zhang D, Wang J, Li J, Jin H, Huang C. Mitochondrial Catalase Induces Cells Transformation Through Nucleolin-dependent Cox-2 mRNA Stabilization. Free Radical Biology & Medicine. PMID 29097213 DOI: 10.1016/j.freeradbiomed.2017.10.387  0.68
2017 Huang H, Jin H, Zhao H, Wang J, Li X, Yan H, Wang S, Guo X, Xue L, Li J, Peng M, Wang A, Zhu J, Wu XR, Chen C, ... Huang C, et al. RhoGDIβ Promotes Sp1/MMP-2 Expression and Bladder Cancer Invasion Through Perturbing miR-200c-Targeted JNK2 Protein Translation. Molecular Oncology. PMID 28846829 DOI: 10.1002/1878-0261.12132  0.68
2017 Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, Zhu J, Wu XR, Huang H, Huang C. p63α protein upregulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion. The Journal of Biological Chemistry. PMID 28794159 DOI: 10.1074/jbc.M117.792010  0.68
2017 Zhu J, Li Y, Chen C, Ma J, Sun W, Tian Z, Li J, Xu J, Liu CS, Zhang D, Huang C, Huang H. NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein. Neoplasia (New York, N.Y.). 19: 672-683. PMID 28772241 DOI: 10.1016/j.neo.2017.06.002  0.68
2017 Zhu J, Li Y, Tian Z, Hua X, Gu J, Li J, Liu C, Jin H, Wang Y, Jiang G, Huang H, Huang C. ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis. Molecular Therapy. Nucleic Acids. 7: 299-313. PMID 28624205 DOI: 10.1016/j.omtn.2017.04.012  0.68
2017 Jiang G, Huang C, Li J, Huang H, Jin H, Zhu J, Wu XR, Huang C. Role of STAT3 and FOXO1 in the divergent therapeutic responses of non-metastatic and metastatic bladder cancer cells to miR-145. Molecular Cancer Therapeutics. PMID 28223425 DOI: 10.1158/1535-7163.MCT-16-0631  0.68
2017 Huang C, Zeng X, Jiang G, Liao X, Liu C, Li J, Jin H, Zhu J, Sun H, Wu XR, Huang C. XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell. Journal of Hematology & Oncology. 10: 6. PMID 28057023 DOI: 10.1186/s13045-016-0376-9  0.68
2016 Zhang R, Che X, Zhang J, Li Y, Li J, Deng X, Zhu J, Jin H, Zhao Q, Huang C. Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation. Oncotarget. PMID 27556506 DOI: 10.18632/oncotarget.11440  0.68
2016 Huang H, Zhu J, Li Y, Zhang L, Gu J, Xie Q, Jin H, Che X, Li J, Huang C, Chen LC, Lyu J, Gao J, Huang C. Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells. Autophagy. 0. PMID 27467530 DOI: 10.1080/15548627.2016.1196313  0.52
2016 Jin H, Xu J, Guo X, Huang H, Li J, Peng M, Zhu J, Tian Z, Wu XR, Tang MS, Huang C. XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells. Oncotarget. PMID 27447744 DOI: 10.18632/oncotarget.10645  0.68
2016 Liang Y, Zhu J, Huang H, Xiang D, Li Y, Zhang D, Li J, Wang Y, Jin H, Jiang G, Liu Z, Huang C. SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers. Autophagy. 0. PMID 27171279 DOI: 10.1080/15548627.2016.1179403  0.68
2016 Zhou H, He F, Mendelsohn CL, Tang MS, Huang C, Wu XR. FGFR3b Extracellular Loop Mutation Lacks Tumorigenicity In Vivo but Collaborates with p53/pRB Deficiency to Induce High-grade Papillary Urothelial Carcinoma. Scientific Reports. 6: 25596. PMID 27157475 DOI: 10.1038/srep25596  0.68
2016 Xu J, Wang Y, Hua X, Xu J, Tian Z, Jin H, Li J, Wu XR, Huang C. Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100). Oncotarget. PMID 27095572 DOI: 10.18632/oncotarget.8746  0.68
2016 Jiang G, Wu AD, Huang C, Gu J, Zhang L, Huang H, Liao X, Li J, Zhang D, Zeng X, Jin H, Huang H, Huang C. Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis. Cancer Prevention Research (Philadelphia, Pa.). PMID 27080594 DOI: 10.1158/1940-6207.CAPR-15-0338  0.52
2016 Huang C, Zhang P, Zhang D, Weng X. The Prognostic Implication of Slug in All Tumor Patients-A Systematic Meta Analysis. European Journal of Clinical Investigation. PMID 26919035 DOI: 10.1111/eci.12608  0.44
2016 Xie Q, Guo X, Gu J, Zhang L, Jin H, Huang H, Li J, Huang C. p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation. Oncotarget. PMID 26918608 DOI: 10.18632/oncotarget.7674  0.68
2016 Xia X, Huang C, Zhang D, Zhang Y, Xue S, Wang X, Zhang Q, Guo L. Molecular cloning, characterization, and the response of Cu/Zn superoxide dismutase and catalase to PBDE-47 and -209 from the freshwater bivalve Anodonta woodiana. Fish & Shellfish Immunology. PMID 26915310 DOI: 10.1016/j.fsi.2016.02.025  0.6
2016 Zeng X, Xu Z, Gu J, Huang H, Gao G, Zhang X, Li J, Jin H, Jiang G, Sun H, Huang C. Induction of miR-137 by isorhapontigenin (ISO) direct targeted Sp1 protein translation and mediated its anti-cancer activity both in vitro and in vivo. Molecular Cancer Therapeutics. PMID 26832795 DOI: 10.1158/1535-7163.MCT-15-0606  0.68
2016 Li ZL, Nan J, Huang C, Liang B, Liu WZ, Cheng HY, Zhang C, Zhang D, Kong D, Kanamaru K, Kobayashi T, Wang AJ, Katayama A. Spatial Abundance and Distribution of Potential Microbes and Functional Genes Associated with Anaerobic Mineralization of Pentachlorophenol in a Cylindrical Reactor. Scientific Reports. 6: 19015. PMID 26750760 DOI: 10.1038/srep19015  0.6
2015 Huang CL, Zhang W, Ni ZY, Zuo T, Zhou M, Xu J, Yang ZF, Li L, Xiao J, Zhang DY. Efficacy of video-assisted thoracoscopic surgery for 29 patients with tuberculosis-destroyed lung. International Journal of Clinical and Experimental Medicine. 8: 18391-8. PMID 26770443  0.48
2015 Ma X, Huang D, Zhao W, Sun L, Xiong H, Zhang Y, Jin M, Zhang D, Huang C, Wang H, Zhang W, Sun N, He L, Tang J. Clinical characteristics and prognosis of childhood rhabdomyosarcoma: a ten-year retrospective multicenter study. International Journal of Clinical and Experimental Medicine. 8: 17196-205. PMID 26770312  0.6
2015 Xu Z, Zeng X, Xu J, Xu D, Li J, Jin H, Jiang G, Han X, Huang C. Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis. Neuro-Oncology. PMID 26681767 DOI: 10.1093/neuonc/nov298  0.68
2015 Du P, Zhao H, Li H, Zhang D, Huang CH, Deng M, Liu C, Cao H. Transformation, products, and pathways of chlorophenols via electro-enzymatic catalysis: How to control toxic intermediate products. Chemosphere. 144: 1674-1681. PMID 26519798 DOI: 10.1016/j.chemosphere.2015.10.038  0.6
2015 Gao MK, Chen YM, Liu Q, Huang C, Li ZY, Zhang DH. Three-Dimensional Path Planning and Guidance of Leg Vascular Based on Improved Ant Colony Algorithm in Augmented Reality. Journal of Medical Systems. 39: 315. PMID 26319273 DOI: 10.1007/s10916-015-0315-2  0.48
2015 Huang H, Pan X, Jin H, Zhang L, Li J, Yang C, Liu P, Liu Y, Chen L, Li Y, Zhu J, Zeng X, Fu K, Chen G, Gao J, ... Huang C, et al. PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE Exposure. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25977341 DOI: 10.1158/1078-0432.CCR-14-2829  0.68
2015 He F, Melamed J, Tang MS, Huang C, Wu XR. Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas. Cancer Research. 75: 2017-28. PMID 25795707 DOI: 10.1158/0008-5472.CAN-14-3067  0.68
2015 Zhang D, Huang C, Xin W, Ma X, Zhang W, Zhang T, Du G. Preclinical pharmacokinetic evaluation and metabolites identification of methyl salicylate-2-O-β-d-lactoside in rats using LC-MS/MS and Q-TOF-MS methods. Journal of Pharmaceutical and Biomedical Analysis. 109: 1-10. PMID 25746501 DOI: 10.1016/j.jpba.2015.02.022  0.6
2015 Zhang D, Liang Y, Xie Q, Gao G, Wei J, Huang H, Li J, Gao J, Huang C. A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability. The Journal of Biological Chemistry. 290: 4784-800. PMID 25561743 DOI: 10.1074/jbc.M114.598219  0.68
2015 Jin H, Yu Y, Hu Y, Lu C, Li J, Gu J, Zhang L, Huang H, Zhang D, Wu XR, Gao J, Huang C. Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines. Oncotarget. 6: 522-36. PMID 25402510  0.68
2015 Jiang S, Xiang D, Chen Q, Goodlin-Fahncke W, Huang C, Yang S, Zhang D, Zhao A. Public support of community corrections in China. International Journal of Offender Therapy and Comparative Criminology. 59: 772-89. PMID 24406472 DOI: 10.1177/0306624X13518381  0.6
2014 Li XH, Gong QM, Ling Y, Huang C, Yu DM, Gu LL, Liao XW, Zhang DH, Hu XQ, Han Y, Kong XF, Zhang XX. Inherent lipid metabolic dysfunction in glycogen storage disease IIIa. Biochemical and Biophysical Research Communications. 455: 90-7. PMID 25451272 DOI: 10.1016/j.bbrc.2014.10.096  0.48
2014 Zhang D, Liu J, Mi X, Liang Y, Li J, Huang C. The N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axis. Cell Death & Disease. 5: e1535. PMID 25412313 DOI: 10.1038/cddis.2014.496  0.68
2014 Zhu J, Zhang J, Huang H, Li J, Yu Y, Jin H, Li Y, Deng X, Gao J, Zhao Q, Huang C. Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the cheliensisin a inhibition of cell transformation. Cancer Prevention Research (Philadelphia, Pa.). 7: 1270-81. PMID 25281487 DOI: 10.1158/1940-6207.CAPR-14-0233  0.68
2014 Zuo Z, Che X, Wang Y, Li B, Li J, Dai W, Lin CP, Huang C. High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression. Oncotarget. 5: 7458-70. PMID 25277185  0.68
2014 Cao Z, Li X, Li J, Luo W, Huang C, Chen J. X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis. Oncotarget. 5: 7126-37. PMID 25216527  0.68
2014 Jiang X, Guo X, Xu X, Teng M, Huang C, Zhang D, Zhang Q, Zhang J, Huang Y. Hypoxia regulates CD9-mediated keratinocyte migration via the P38/MAPK pathway. Scientific Reports. 4: 6304. PMID 25200404 DOI: 10.1038/srep06304  0.6
2014 Wei J, Du K, Cai Q, Ma L, Jiao Z, Tan J, Xu Z, Li J, Luo W, Chen J, Gao J, Zhang D, Huang C. Lead induces COX-2 expression in glial cells in a NFAT-dependent, AP-1/NFκB-independent manner. Toxicology. 325: 67-73. PMID 25193092 DOI: 10.1016/j.tox.2014.08.012  0.68
2014 Fang Y, Wang Y, Wang Y, Meng Y, Zhu J, Jin H, Li J, Zhang D, Yu Y, Wu XR, Huang C. A new tumour suppression mechanism by p27Kip1: EGFR down-regulation mediated by JNK/c-Jun pathway inhibition. The Biochemical Journal. 463: 383-92. PMID 25121353 DOI: 10.1042/BJ20140103  0.68
2014 Gao G, Chen L, Huang C. Anti-cancer drug discovery: update and comparisons in yeast, Drosophila, and zebrafish. Current Molecular Pharmacology. 7: 44-51. PMID 24993385  0.32
2014 Gao G, Chen L, Li J, Zhang D, Fang Y, Huang H, Chen X, Huang C. Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA Stability. Oncotarget. 5: 2664-77. PMID 24797581 DOI: 10.18632/oncotarget.1872  0.68
2014 Guo W, Liu J, Jian J, Li J, Wan Y, Huang C. IKK-β/NF-κB p65 mediates p27(Kip1) protein degradation in arsenite response. Biochemical and Biophysical Research Communications. 447: 563-8. PMID 24751519 DOI: 10.1016/j.bbrc.2014.04.055  0.68
2014 Zhang D, Wang Y, Liang Y, Zhang M, Wei J, Zheng X, Li F, Meng Y, Zhu NW, Li J, Wu XR, Huang C. Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration. Journal of Cell Science. 127: 2920-33. PMID 24727615 DOI: 10.1242/jcs.148130  0.68
2014 Xin W, Huang C, Zhang X, Xin S, Zhou Y, Ma X, Zhang D, Li Y, Zhou S, Zhang D, Zhang T, Du G. Methyl salicylate lactoside inhibits inflammatory response of fibroblast-like synoviocytes and joint destruction in collagen-induced arthritis in mice. British Journal of Pharmacology. 171: 3526-38. PMID 24712652 DOI: 10.1111/bph.12715  0.6
2014 Yu H, He X, Xie W, Xiong J, Sheng H, Guo S, Huang C, Zhang D, Zhang K. Elastase LasB of Pseudomonas aeruginosa promotes biofilm formation partly through rhamnolipid-mediated regulation. Canadian Journal of Microbiology. 60: 227-35. PMID 24693981 DOI: 10.1139/cjm-2013-0667  0.6
2014 Zhang J, Gao G, Chen L, Li J, Deng X, Zhao QS, Huang C. Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells. Oncotarget. 5: 841-52. PMID 24553354 DOI: 10.18632/oncotarget.1780  0.68
2014 Yang J, Hu L, Song T, Liu Y, Wu Q, Zhao L, Liu L, Zhao X, Zhang D, Huang C. Proteomic changes in female rat hippocampus following exposure to a terrified sound stress. Journal of Molecular Neuroscience : Mn. 53: 158-65. PMID 24510750 DOI: 10.1007/s12031-014-0242-6  0.6
2014 Huang H, Ma L, Li J, Yu Y, Zhang D, Wei J, Jin H, Xu D, Gao J, Huang C. NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression. Oncotarget. 5: 493-505. PMID 24457827 DOI: 10.18632/oncotarget.1643  0.68
2014 Zhang R, Wang Y, Li J, Jin H, Song S, Huang C. The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade. The Journal of Biological Chemistry. 289: 6394-403. PMID 24451377 DOI: 10.1074/jbc.M113.513960  0.68
2014 Cao Z, Li X, Li J, Kang B, Chen J, Luo W, Huang C. SUMOylation of RhoGDIα is required for its repression of cyclin D1 expression and anchorage-independent growth of cancer cells. Molecular Oncology. 8: 285-96. PMID 24342356 DOI: 10.1016/j.molonc.2013.11.006  0.68
2014 Liu W, Li Z, Huang CH, Guo RT, Zhao L, Zhang D, Chen X, Wu Q, Zhu D. Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum. Chembiochem : a European Journal of Chemical Biology. 15: 217-22. PMID 24339368 DOI: 10.1002/cbic.201300691  0.6
2014 Hu L, Yang J, Song T, Hou N, Liu Y, Zhao X, Zhang D, Wang L, Wang T, Huang C. A new stress model, a scream sound, alters learning and monoamine levels in rat brain. Physiology & Behavior. 123: 105-13. PMID 24096192 DOI: 10.1016/j.physbeh.2013.09.010  0.6
2013 Du K, Yu Y, Zhang D, Luo W, Huang H, Chen J, Gao J, Huang C. NFκB1 (p50) suppresses SOD2 expression by inhibiting FoxO3a transactivation in a miR190/PHLPP1/Akt-dependent axis. Molecular Biology of the Cell. 24: 3577-83. PMID 24068327 DOI: 10.1091/mbc.E13-06-0343  0.6
2013 Zhang J, Gao G, Chen L, Deng X, Li J, Yu Y, Zhang D, Li F, Zhang M, Zhao Q, Huang C. Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis. Cancer Prevention Research (Philadelphia, Pa.). 6: 949-58. PMID 23852422 DOI: 10.1158/1940-6207.CAPR-13-0097  0.68
2013 Fang Y, Cao Z, Hou Q, Ma C, Yao C, Li J, Wu XR, Huang C. Cyclin d1 downregulation contributes to anticancer effect of isorhapontigenin on human bladder cancer cells. Molecular Cancer Therapeutics. 12: 1492-503. PMID 23723126 DOI: 10.1158/1535-7163.MCT-12-0922  0.68
2013 Cao Z, Zhang R, Li J, Huang H, Zhang D, Zhang J, Gao J, Chen J, Huang C. X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis. The Journal of Biological Chemistry. 288: 20238-47. PMID 23720779 DOI: 10.1074/jbc.M112.448365  0.68
2013 Che X, Liu J, Huang H, Mi X, Xia Q, Li J, Zhang D, Ke Q, Gao J, Huang C. p27 suppresses cyclooxygenase-2 expression by inhibiting p38β and p38δ-mediated CREB phosphorylation upon arsenite exposure. Biochimica Et Biophysica Acta. 1833: 2083-91. PMID 23639288 DOI: 10.1016/j.bbamcr.2013.04.012  0.68
2013 Yu Y, Li J, Wan Y, Lu J, Gao J, Huang C. GADD45α induction by nickel negatively regulates JNKs/p38 activation via promoting PP2Cα expression. Plos One. 8: e57185. PMID 23536762 DOI: 10.1371/journal.pone.0057185  0.68
2012 Zhang D, Li J, Zhang M, Gao G, Zuo Z, Yu Y, Zhu L, Gao J, Huang C. The requirement of c-Jun N-terminal kinase 2 in regulation of hypoxia-inducing factor-1α mRNA stability Journal of Biological Chemistry. 287: 34361-34371. PMID 22910906 DOI: 10.1074/jbc.M112.365882  0.32
2012 Fang Y, Yu Y, Hou Q, Zheng X, Zhang M, Zhang D, Li J, Wu XR, Huang C. The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP. The Journal of Biological Chemistry. 287: 35234-43. PMID 22896709 DOI: 10.1074/jbc.M112.389494  0.68
2012 Zhang J, Ouyang W, Li J, Zhang D, Yu Y, Wang Y, Li X, Huang C. Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability. Toxicology and Applied Pharmacology. 263: 218-24. PMID 22749963 DOI: 10.1016/j.taap.2012.06.012  0.32
2012 Che X, Huang C. microRNA, Cancer and Cancer Chemoprevention. Current Molecular Pharmacology. PMID 22697394  0.32
2012 Liu J, Zhang D, Luo W, Yu J, Li J, Yu Y, Zhang X, Chen J, Wu XR, Huang C. E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activity. Plos One. 7: e35682. PMID 22532870 DOI: 10.1371/journal.pone.0035682  0.68
2012 Zuo Z, Cai T, Li J, Zhang D, Yu Y, Huang C. Hexavalent chromium Cr(VI) up-regulates COX-2 expression through an NFκB/c-Jun/AP-1-dependent pathway. Environmental Health Perspectives. 120: 547-53. PMID 22472290 DOI: 10.1289/ehp.1104179  0.68
2012 Yu J, Zhang D, Liu J, Li J, Yu Y, Wu XR, Huang C. RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility. The Journal of Biological Chemistry. 287: 13752-60. PMID 22393046 DOI: 10.1074/jbc.M111.337469  0.68
2012 Zhou H, Huang HY, Shapiro E, Lepor H, Huang WC, Mohammadi M, Mohr I, Tang MS, Huang C, Wu XR. Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies. Carcinogenesis. 33: 770-80. PMID 22287562 DOI: 10.1093/carcin/bgs025  0.68
2011 Cai T, Li X, Ding J, Luo W, Li J, Huang C. A cross-talk between NFAT and NF-κB pathways is crucial for nickel-induced COX-2 expression in Beas-2B cells. Current Cancer Drug Targets. 11: 548-59. PMID 21486220  0.68
2011 Liu J, Zhang D, Luo W, Yu Y, Yu J, Li J, Zhang X, Zhang B, Chen J, Wu XR, Rosas-Acosta G, Huang C. X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton. The Journal of Biological Chemistry. 286: 15630-40. PMID 21402697 DOI: 10.1074/jbc.M110.176982  0.68
2011 Cai T, Che H, Yao T, Chen Y, Huang C, Zhang W, Du K, Zhang J, Cao Y, Chen J, Luo W. Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 119: 169-77. PMID 20937724 DOI: 10.1093/toxsci/kfq308  0.52
2011 Guo W, Yang Z, Xia Q, Liu J, Yu Y, Li J, Zuo Z, Zhang D, Li X, Shi X, Huang C. Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression. Cellular and Molecular Life Sciences : Cmls. 68: 475-88. PMID 20835880 DOI: 10.1007/s00018-010-0459-7  0.68
2010 Liu J, Zhang D, Mi X, Xia Q, Yu Y, Zuo Z, Guo W, Zhao X, Cao J, Yang Q, Zhu A, Yang W, Shi X, Li J, Huang C. p27 suppresses arsenite-induced Hsp27/Hsp70 expression through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways. The Journal of Biological Chemistry. 285: 26058-65. PMID 20566634 DOI: 10.1074/jbc.M110.100271  0.68
2010 Luo W, Li J, Zhang D, Cai T, Song L, Yin XM, Desai D, Amin S, Chen J, Huang C. Bid mediates anti-apoptotic COX-2 induction through the IKKbeta/NFkappaB pathway due to 5-MCDE exposure. Current Cancer Drug Targets. 10: 96-106. PMID 20088789  0.68
2010 Song L, Dong W, Gao M, Li J, Hu M, Guo N, Huang C. A novel role of IKKalpha in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression. Biochimica Et Biophysica Acta. 1803: 323-32. PMID 20080131 DOI: 10.1016/j.bbamcr.2010.01.006  0.68
2010 Zhang D, Li J, Costa M, Gao J, Huang C. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70. Cancer Research. 70: 813-23. PMID 20068160 DOI: 10.1158/0008-5472.CAN-09-0448  0.68
2009 Gao M, Guo N, Huang C, Song L. Diverse roles of GADD45alpha in stress signaling. Current Protein & Peptide Science. 10: 388-94. PMID 19689359  0.44
2009 Liu M, Cai T, Zhao F, Zheng G, Wang Q, Chen Y, Huang C, Luo W, Chen J. Effect of microglia activation on dopaminergic neuronal injury induced by manganese, and its possible mechanism. Neurotoxicity Research. 16: 42-9. PMID 19526297 DOI: 10.1007/s12640-009-9045-x  0.52
2009 Yu Y, Wan Y, Huang C. The biological functions of NF-kappaB1 (p50) and its potential as an anti-cancer target. Current Cancer Drug Targets. 9: 566-71. PMID 19519322  0.52
2009 Ding J, Ning B, Huang Y, Zhang D, Li J, Chen CY, Huang C. PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite-induced cyclin D1 expression and cell growth in human bronchial epithelial cells. Current Cancer Drug Targets. 9: 500-9. PMID 19519318  0.68
2009 Ding J, He G, Gong W, Wen W, Sun W, Ning B, Huang S, Wu K, Huang C, Wu M, Xie W, Wang H. Effects of nickel on cyclin expression, cell cycle progression and cell proliferation in human pulmonary cells. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1720-9. PMID 19505905 DOI: 10.1158/1055-9965.EPI-09-0115  0.36
2009 Zheng G, Zhang W, Zhang Y, Chen Y, Liu M, Yao T, Yang Y, Zhao F, Li J, Huang C, Luo W, Chen J. gamma-Aminobutyric acid(A) (GABA(A)) receptor regulates ERK1/2 phosphorylation in rat hippocampus in high doses of methyl tert-butyl ether (MTBE)-induced impairment of spatial memory. Toxicology and Applied Pharmacology. 236: 239-45. PMID 19344668 DOI: 10.1016/j.taap.2009.01.004  0.68
2009 Ding J, Huang Y, Ning B, Gong W, Li J, Wang H, Chen CY, Huang C. TNF-alpha induction by nickel compounds is specific through ERKs/AP-1-dependent pathway in human bronchial epithelial cells. Current Cancer Drug Targets. 9: 81-90. PMID 19200052  0.68
2009 Zhang D, Li J, Gao J, Huang C. c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells. Toxicology and Applied Pharmacology. 235: 18-24. PMID 19059425 DOI: 10.1016/j.taap.2008.11.002  0.68
2009 Ouyang W, Zhang D, Li J, Verma UN, Costa M, Huang C. Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation. Journal of Cellular Physiology. 218: 205-14. PMID 18792914 DOI: 10.1002/jcp.21590  0.68
2008 Shen F, Fan X, Liu B, Jia X, Gao A, Du H, Ye M, You B, Huang C, Shi X. Downregulation of cyclin D1-CDK4 protein in human embryonic lung fibroblasts (HELF) induced by silica is mediated through the ERK and JNK pathway. Cell Biology International. 32: 1284-92. PMID 18703151 DOI: 10.1016/j.cellbi.2008.07.015  0.36
2008 Song L, Li J, Hu M, Huang C. Both IKKalpha and IKKbeta are implicated in the arsenite-induced AP-1 transactivation correlating with cell apoptosis through NF-kappaB activity-independent manner. Experimental Cell Research. 314: 2187-98. PMID 18508047 DOI: 10.1016/j.yexcr.2008.04.002  0.68
2008 Jiao S, Liu B, Gao A, Ye M, Jia X, Zhang F, Liu H, Shi X, Huang C. Benzo(a)pyrene-caused increased G1-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts. Toxicology Letters. 178: 167-75. PMID 18448277 DOI: 10.1016/j.toxlet.2008.03.012  0.36
2008 Zhang D, Li J, Song L, Ouyang W, Gao J, Huang C. A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression. Molecular Cancer Research : McR. 6: 165-74. PMID 18234971 DOI: 10.1158/1541-7786.MCR-07-0181  0.68
2008 Luo W, Liu J, Li J, Zhang D, Liu M, Addo JK, Patil S, Zhang L, Yu J, Buolamwini JK, Chen J, Huang C. Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. The Journal of Biological Chemistry. 283: 8624-33. PMID 18218619 DOI: 10.1074/jbc.M707860200  0.4
2008 Ouyang W, Luo W, Zhang D, Jian J, Ma Q, Li J, Shi X, Chen J, Gao J, Huang C. PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation. Environmental Health Perspectives. 116: 1-6. PMID 18197291 DOI: 10.1289/ehp.10403  0.68
2008 Li J, Zhang D, Stoner GD, Huang C. Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes. Molecular Carcinogenesis. 47: 286-94. PMID 18085529 DOI: 10.1002/mc.20377  0.4
2007 Ding J, Wu K, Zhang D, Luo W, Li J, Ouyang W, Song L, Huang C. Activation of both nuclear factor of activated T cells and inhibitor of nuclear factor-kappa B kinase beta-subunit-/nuclear factor-kappa B is critical for cyclooxygenase-2 induction by benzo[a]pyrene in human bronchial epithelial cells. Cancer Science. 98: 1323-9. PMID 17640307 DOI: 10.1111/j.1349-7006.2007.00530.x  0.68
2007 Huang C, Zhang D, Li J, Tong Q, Stoner GD. Differential inhibition of UV-induced activation of NF kappa B and AP-1 by extracts from black raspberries, strawberries, and blueberries. Nutrition and Cancer. 58: 205-12. PMID 17640167 DOI: 10.1080/01635580701328453  0.4
2007 Stoner GD, Wang LS, Zikri N, Chen T, Hecht SS, Huang C, Sardo C, Lechner JF. Cancer prevention with freeze-dried berries and berry components. Seminars in Cancer Biology. 17: 403-10. PMID 17574861 DOI: 10.1016/j.semcancer.2007.05.001  0.36
2007 Ouyang W, Hu Y, Li J, Ding M, Lu Y, Zhang D, Yan Y, Song L, Qu Q, Desai D, Amin S, Huang C. Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells. Carcinogenesis. 28: 2218-26. PMID 17522069 DOI: 10.1093/carcin/bgm115  0.68
2007 Ouyang W, Zhang D, Ma Q, Li J, Huang C. Cyclooxygenase-2 induction by arsenite through the IKKbeta/NFkappaB pathway exerts an antiapoptotic effect in mouse epidermal Cl41 cells. Environmental Health Perspectives. 115: 513-8. PMID 17450217 DOI: 10.1289/ehp.9588  0.68
2007 Gao A, Liu B, Shi X, Jia X, Ye M, Jiao S, You B, Huang C. Phosphatidylinositol-3 kinase/Akt/p70S6K/AP-1 signaling pathway mediated benzo(a)pyrene-induced cell cycle alternation via cell cycle regulatory proteins in human embryo lung fibroblasts. Toxicology Letters. 170: 30-41. PMID 17383120 DOI: 10.1016/j.toxlet.2007.02.008  0.36
2007 Song L, Li J, Ye J, Yu G, Ding J, Zhang D, Ouyang W, Dong Z, Kim SO, Huang C. p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation. Molecular and Cellular Biology. 27: 2713-31. PMID 17242187 DOI: 10.1128/MCB.00657-06  0.68
2007 Zhang D, Li J, Wu K, Ouyang W, Ding J, Liu ZG, Costa M, Huang C. JNK1, but not JNK2, is required for COX-2 induction by nickel compounds. Carcinogenesis. 28: 883-91. PMID 17065197 DOI: 10.1093/carcin/bgl186  0.68
2007 Ouyang W, Ma Q, Li J, Zhang D, Ding J, Huang Y, Xing MM, Huang C. Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKbeta/NF-kappaB in mouse epidermal Cl41 cells. Molecular Carcinogenesis. 46: 32-41. PMID 16921490 DOI: 10.1002/mc.20260  0.68
2006 Song L, Li J, Zhang D, Liu ZG, Ye J, Zhan Q, Shen HM, Whiteman M, Huang C. IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response. The Journal of Cell Biology. 175: 607-17. PMID 17116751 DOI: 10.1083/jcb.200602149  0.68
2006 Ding J, Zhang X, Li J, Song L, Ouyang W, Zhang D, Xue C, Costa M, Meléndez JA, Huang C. Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of cyclooxygenase-2 through an IKKbeta/p65-dependent and IKKalpha- and p50-independent pathway. The Journal of Biological Chemistry. 281: 39022-32. PMID 16982623 DOI: 10.1074/jbc.M604798200  0.68
2006 Tong Q, Zheng L, Li B, Wang D, Huang C, Matuschak GM, Li D. Hypoxia-induced mitogenic factor enhances angiogenesis by promoting proliferation and migration of endothelial cells. Experimental Cell Research. 312: 3559-69. PMID 16982054 DOI: 10.1016/j.yexcr.2006.07.024  0.32
2006 Zhang D, Song L, Li J, Wu K, Huang C. Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses. The Journal of Biological Chemistry. 281: 34113-23. PMID 16973625 DOI: 10.1074/jbc.M602821200  0.68
2006 Tong Q, Zheng L, Lin L, Li B, Wang D, Huang C, Matuschak GM, Li D. Participation of the PI-3K/Akt-NF-kappa B signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 expression in endothelial cells. Respiratory Research. 7: 101. PMID 16872509 DOI: 10.1186/1465-9921-7-101  0.32
2006 Ding J, Li J, Xue C, Wu K, Ouyang W, Zhang D, Yan Y, Huang C. Cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells. The Journal of Biological Chemistry. 281: 24405-13. PMID 16809336 DOI: 10.1074/jbc.M600751200  0.68
2006 Yan Y, Li J, Ouyang W, Ma Q, Hu Y, Zhang D, Ding J, Qu Q, Subbaramaiah K, Huang C. NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells. Journal of Cell Science. 119: 2985-94. PMID 16803872 DOI: 10.1242/jcs.03014  0.68
2006 Lu H, Li J, Zhang D, Stoner GD, Huang C. Molecular mechanisms involved in chemoprevention of black raspberry extracts: from transcription factors to their target genes. Nutrition and Cancer. 54: 69-78. PMID 16800774 DOI: 10.1207/s15327914nc5401_8  0.36
2006 Zhang D, Lu H, Li J, Shi X, Huang C. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B. Molecular and Cellular Biochemistry. 293: 161-71. PMID 16786188 DOI: 10.1007/s11010-006-9238-z  0.68
2006 Li J, Lu H, Huang C. NFAT3 is required for EGF-induced COX-2 transcription, but neither iNOS transcription nor cell transformation in Cl 41 cells. Molecular and Cellular Biochemistry. 289: 73-82. PMID 16718377 DOI: 10.1007/s11010-006-9149-z  0.68
2006 Lu B, Wang L, Stehlik C, Medan D, Huang C, Hu S, Chen F, Shi X, Rojanasakul Y. Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 6785-93. PMID 16709838  0.36
2006 Ding J, Zhang R, Li J, Xue C, Huang C. Involvement of nuclear factor of activated T cells 3 (NFAT3) in cyclin D1 induction by B[a]PDE or B[a]PDE and ionizing radiation in mouse epidermal Cl 41 cells. Molecular and Cellular Biochemistry. 287: 117-25. PMID 16645724 DOI: 10.1007/s11010-005-9087-1  0.68
2006 Lu H, Ouyang W, Huang C. Inflammation, a key event in cancer development. Molecular Cancer Research : McR. 4: 221-33. PMID 16603636 DOI: 10.1158/1541-7786.MCR-05-0261  0.36
2006 Hecht SS, Huang C, Stoner GD, Li J, Kenney PM, Sturla SJ, Carmella SG. Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFkappaB and AP-1 activity. Carcinogenesis. 27: 1617-26. PMID 16522666 DOI: 10.1093/carcin/bgi366  0.36
2006 Tong Q, Zheng L, Lin L, Li B, Wang D, Huang C, Li D. VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-kappaB signaling pathway. Respiratory Research. 7: 37. PMID 16512910 DOI: 10.1186/1465-9921-7-37  0.32
2006 Ke Q, Li J, Ding J, Ding M, Wang L, Liu B, Costa M, Huang C. Essential role of ROS-mediated NFAT activation in TNF-alpha induction by crystalline silica exposure. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L257-64. PMID 16489119 DOI: 10.1152/ajplung.00007.2006  0.68
2006 Li J, Song L, Zhang D, Wei L, Huang C. Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells. Journal of Cellular Biochemistry. 99: 1010-20. PMID 16475165 DOI: 10.1002/jcb.20834  0.68
2006 Zhang R, Li J, Burns FJ, Huang C. Ionizing radiation synergistic induction of cyclooxygenase-2 with benzo[a]pyrene diol-epoxide through nuclear factor of activated T cells in mouse epidermal Cl 41 cells. Oncology Reports. 15: 721-7. PMID 16465436  0.68
2006 Ding J, Li J, Chen J, Chen H, Ouyang W, Zhang R, Xue C, Zhang D, Amin S, Desai D, Huang C. Effects of polycyclic aromatic hydrocarbons (PAHs) on vascular endothelial growth factor induction through phosphatidylinositol 3-kinase/AP-1-dependent, HIF-1alpha-independent pathway. The Journal of Biological Chemistry. 281: 9093-100. PMID 16461351 DOI: 10.1074/jbc.M510537200  0.68
2006 Huang C, Li J, Song L, Zhang D, Tong Q, Ding M, Bowman L, Aziz R, Stoner GD. Black raspberry extracts inhibit benzo(a)pyrene diol-epoxide-induced activator protein 1 activation and VEGF transcription by targeting the phosphotidylinositol 3-kinase/Akt pathway. Cancer Research. 66: 581-7. PMID 16397275 DOI: 10.1158/0008-5472.CAN-05-1951  0.4
2006 Ouyang W, Li J, Ma Q, Huang C. Essential roles of PI-3K/Akt/IKKbeta/NFkappaB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells. Carcinogenesis. 27: 864-73. PMID 16387740 DOI: 10.1093/carcin/bgi321  0.68
2006 Ding M, Huang C, Lu Y, Bowman L, Castranova V, Vallyathan V. Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L291-7. PMID 16169898 DOI: 10.1152/ajplung.00053.2005  0.32
2006 Shen F, Fan X, Liu B, Jia X, Du H, You B, Ye M, Huang C, Shi X. Overexpression of cyclin D1-CDK4 in silica-induced transformed cells is due to activation of ERKs, JNKs/AP-1 pathway. Toxicology Letters. 160: 185-95. PMID 16125882 DOI: 10.1016/j.toxlet.2005.07.009  0.36
2005 Lu H, Shi X, Costa M, Huang C. Carcinogenic effect of nickel compounds. Molecular and Cellular Biochemistry. 279: 45-67. PMID 16283514 DOI: 10.1007/s11010-005-8215-2  0.36
2005 Ouyang W, Li J, Shi X, Costa M, Huang C. Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression. Molecular and Cellular Biochemistry. 279: 35-43. PMID 16283513 DOI: 10.1007/s11010-005-8214-3  0.68
2005 Li J, Tong Q, Shi X, Costa M, Huang C. ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells. Molecular and Cellular Biochemistry. 279: 25-33. PMID 16283512 DOI: 10.1007/s11010-005-8212-5  0.68
2005 Ouyang W, Ma Q, Li J, Zhang D, Liu ZG, Rustgi AK, Huang C. Cyclin D1 induction through IκB kinase β/nuclear factor-κB pathway is responsible for arsenite-induced increased cell cycle G 1-S phase transition in human keratinocytes Cancer Research. 65: 9287-9293. PMID 16230390 DOI: 10.1158/0008-5472.CAN-05-0469  0.4
2005 Wang J, Ouyang W, Li J, Wei L, Ma Q, Zhang Z, Tong Q, He J, Huang C. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation. Cancer Research. 65: 6601-11. PMID 16061640 DOI: 10.1158/0008-5472.CAN-04-4184  0.68
2005 Costa M, Davidson TL, Chen H, Ke Q, Zhang P, Yan Y, Huang C, Kluz T. Nickel carcinogenesis: epigenetics and hypoxia signaling. Mutation Research. 592: 79-88. PMID 16009382 DOI: 10.1016/j.mrfmmm.2005.06.008  0.32
2005 Ma C, Bower KA, Lin H, Chen G, Huang C, Shi X, Luo J. The role of epidermal growth factor receptor in ethanol-mediated inhibition of activator protein-1 transactivation. Biochemical Pharmacology. 69: 1785-94. PMID 15878157 DOI: 10.1016/j.bcp.2005.03.029  0.36
2005 Chen J, Yan Y, Li J, Ma Q, Stoner GD, Ye J, Huang C. Differential requirement of signal pathways for benzo[a]pyrene (B[a]P)-induced nitric oxide synthase (iNOS) in rat esophageal epithelial cells. Carcinogenesis. 26: 1035-43. PMID 15718251 DOI: 10.1093/carcin/bgi052  0.36
2004 Li J, Chen H, Ke Q, Feng Z, Tang MS, Liu B, Amin S, Costa M, Huang C. Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kappaB in mouse epidermal cl41 cells. Molecular Carcinogenesis. 40: 104-15. PMID 15170815 DOI: 10.1002/mc.20020  0.68
2004 Li J, Chen H, Tang MS, Shi X, Amin S, Desai D, Costa M, Huang C. PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells. The Journal of Cell Biology. 165: 77-86. PMID 15067018 DOI: 10.1083/jcb.200401004  0.68
2004 Li J, Tang MS, Liu B, Shi X, Huang C. A critical role of PI-3K/Akt/JNKs pathway in benzo[a]pyrene diol-epoxide (B[a]PDE)-induced AP-1 transactivation in mouse epidermal Cl41 cells. Oncogene. 23: 3932-44. PMID 15021902 DOI: 10.1038/sj.onc.1207501  0.68
2004 Zhang Z, Gao N, He H, Huang C, Jiang BH, Jia L, Shi X. The role of phosphatidylinositol-3 kinase in vanadate-promoted S phase entry. Molecular and Cellular Biochemistry. 255: 239-45. PMID 14971664  0.36
2004 Zhang Z, Gao N, He H, Huang C, Luo J, Shi X. Vanadate activated Akt and promoted S phase entry. Molecular and Cellular Biochemistry. 255: 227-37. PMID 14971663  0.36
2004 Li J, Dokka S, Wang L, Shi X, Castranova V, Yan Y, Costa M, Huang C. Activation of aPKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells. Molecular and Cellular Biochemistry. 255: 217-25. PMID 14971662  0.68
2004 Huang C, Ke Q, Costa M, Shi X. Molecular mechanisms of arsenic carcinogenesis. Molecular and Cellular Biochemistry. 255: 57-66. PMID 14971646  0.36
2004 Li J, Davidson G, Huang Y, Jiang BH, Shi X, Costa M, Huang C. Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells. Cancer Research. 64: 94-101. PMID 14729612  0.68
2004 Ding M, Lu Y, Bowman L, Huang C, Leonard S, Wang L, Vallyathan V, Castranova V, Shi X. Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract. The Journal of Biological Chemistry. 279: 10670-6. PMID 14665633 DOI: 10.1074/jbc.M311465200  0.36
2003 Zhang Z, Leonard SS, Huang C, Vallyathan V, Castranova V, Shi X. Role of reactive oxygen species and MAPKs in vanadate-induced G(2)/M phase arrest. Free Radical Biology & Medicine. 34: 1333-42. PMID 12726921  0.36
2003 Wang L, Medan D, Mercer R, Overmiller D, Leornard S, Castranova V, Shi X, Ding M, Huang C, Rojanasakul Y. Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen species. Journal of Cellular Physiology. 195: 99-107. PMID 12599213 DOI: 10.1002/jcp.10232  0.36
2003 Li J, Ma C, Huang Y, Luo J, Huang C. Differential requirement of EGF receptor and its tyrosine kinase for AP-1 transactivation induced by EGF and TPA. Oncogene. 22: 211-9. PMID 12527890 DOI: 10.1038/sj.onc.1206102  0.68
2003 Luo J, Sun Y, Lin H, Qian Y, Li Z, Leonard SS, Huang C, Shi X. Activation of JNK by vanadate induces a Fas-associated death domain (FADD)-dependent death of cerebellar granule progenitors in vitro. The Journal of Biological Chemistry. 278: 4542-51. PMID 12454017 DOI: 10.1074/jbc.M208295200  0.36
2002 Wang L, Medan D, Mercer R, Shi X, Huang C, Castranova V, Ding M, Rojanasakul Y. Role of neutrophil apoptosis in vanadium-induced pulmonary inflammation in mice. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 21: 343-50. PMID 12510963  0.36
2002 Huang C, Huang Y, Li J, Hu W, Aziz R, Tang MS, Sun N, Cassady J, Stoner GD. Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extracts. Cancer Research. 62: 6857-63. PMID 12460899  0.4
2002 Zhang Z, Chen F, Huang C, Shi X. Vanadate induces G2/M phase arrest in p53-deficient mouse embryo fibroblasts. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 21: 223-31. PMID 12435075  0.36
2002 Huang Y, Davidson G, Li J, Yan Y, Chen F, Costa M, Chen LC, Huang C. Activation of nuclear factor-kappaB and not activator protein-1 in cellular response to nickel compounds. Environmental Health Perspectives. 110: 835-9. PMID 12426142  0.68
2002 Huang C, Li J, Zhang Q, Huang X. Role of bioavailable iron in coal dust-induced activation of activator protein-1 and nuclear factor of activated T cells: difference between Pennsylvania and Utah coal dusts. American Journal of Respiratory Cell and Molecular Biology. 27: 568-74. PMID 12397016 DOI: 10.1165/rcmb.4821  0.68
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