Igor Kovalchuk - Publications

Affiliations: 
Biological Studies University of Lethbridge (Canada) 
Area:
Molecular Biology, Plant Culture Agriculture, Agricultural Engineering

201 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kovalchuk A, Wang B, Li D, Rodriguez-Juarez R, Ilnytskyy S, Kovalchuk I, Kovalchuk O. Fighting the storm: could novel anti-TNFα and anti-IL-6 cultivars tame cytokine storm in COVID-19? Aging. 13. PMID 33465050 DOI: 10.18632/aging.202500  0.96
2020 Suryavanshi SV, Kovalchuk I, Kovalchuk O. Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective. Frontiers in Immunology. 11: 613613. PMID 33584697 DOI: 10.3389/fimmu.2020.613613  0.96
2020 Borisov N, Ilnytskyy Y, Byeon B, Kovalchuk O, Kovalchuk I. System, Method and Software for Calculation of a Cannabis Drug Efficiency Index for the Reduction of Inflammation. International Journal of Molecular Sciences. 22. PMID 33396562 DOI: 10.3390/ijms22010388  0.96
2020 Wang B, Kovalchuk A, Li D, Rodriguez-Juarez R, Ilnytskyy Y, Kovalchuk I, Kovalchuk O. In search of preventative strategies: novel high-CBD extracts modulate ACE2 expression in COVID-19 gateway tissues. Aging. 12. PMID 33221759 DOI: 10.18632/aging.202225  0.96
2020 Singh A, Bilichak A, Kovalchuk I. The genetics of Cannabis - genomic variations of key synthases and their effect on cannabinoids content. Genome. PMID 33186070 DOI: 10.1139/gen-2020-0087  0.68
2020 Bressler KR, Ross JA, Ilnytskyy S, Vanden Dungen K, Taylor K, Patel K, Zovoilis A, Kovalchuk I, Thakor N. Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK). Cell Stress & Chaperones. PMID 33123915 DOI: 10.1007/s12192-020-01174-1  0.36
2020 Gerasymchuk M, Cherkasova V, Kovalchuk O, Kovalchuk I. The Role of microRNAs in Organismal and Skin Aging. International Journal of Molecular Sciences. 21. PMID 32722415 DOI: 10.3390/ijms21155281  0.96
2020 Gaudet D, Yadav NS, Sorokin A, Bilichak A, Kovalchuk I. Development and Optimization of a Germination Assay and Long-Term Storage for Pollen. Plants (Basel, Switzerland). 9. PMID 32456251 DOI: 10.3390/plants9050665  0.68
2020 Kovalchuk O, Kovalchuk I. Cannabinoids as anticancer therapeutic agents. Cell Cycle (Georgetown, Tex.). 19: 961-989. PMID 32249682 DOI: 10.1080/15384101.2020.1742952  0.96
2020 Ambeskovic M, Ilnytskyy Y, Kiss D, Currie C, Montina T, Kovalchuk I, Metz GAS. Ancestral stress programs sex-specific biological aging trajectories and non-communicable disease risk. Aging. 12. PMID 32087063 DOI: 10.18632/aging.102848  0.88
2019 Kingston D, Mughal MK, Arshad M, Kovalchuk I, Metz GAS, Wynne-Edwards K, King S, Jiang S, Postovit L, Wajid A, McDonald S, Slater DM, Tough SC, Aitchison K, Arnold P. Prediction and Understanding of Resilience in Albertan Families: Longitudinal Study of Disaster Responses (PURLS) - Protocol. Frontiers in Psychiatry. 10: 729. PMID 31736793 DOI: 10.3389/fpsyt.2019.00729  0.6
2019 Wang B, Li D, Yao Y, Mieke H, Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Bronson RT, Metz GAS, Kovalchuk O, Kovalchuk I. The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network. Cell Cycle (Georgetown, Tex.). 1-17. PMID 31522595 DOI: 10.1080/15384101.2019.1652033  0.96
2019 Ambeskovic M, Babenko O, Ilnytskyy Y, Kovalchuk I, Kolb B, Metz GAS. Ancestral Stress Alters Lifetime Mental Health Trajectories and Cortical Neuromorphology via Epigenetic Regulation. Scientific Reports. 9: 6389. PMID 31011159 DOI: 10.1038/s41598-019-42691-z  0.88
2019 Byeon B, Bilichak A, Kovalchuk I. Transgenerational Response to Heat Stress in the Form of Differential Expression of Noncoding RNA Fragments in Plants. The Plant Genome. 12. PMID 30951085 DOI: 10.3835/plantgenome2018.04.0022  0.68
2018 Wang B, Li D, Rodriguez-Juarez R, Farfus A, Storozynsky Q, Malach M, Carpenter E, Filkowski J, Lykkesfeldt AE, Kovalchuk O. A suppressive role of guanine nucleotide-binding protein subunit beta-4 inhibited by DNA methylation in the growth of anti-estrogen resistant breast cancer cells. Bmc Cancer. 18: 817. PMID 30103729 DOI: 10.1186/s12885-018-4711-0  0.44
2018 Wang B, Li D, Filkowski J, Rodriguez-Juarez R, Storozynsky Q, Malach M, Carpenter E, Kovalchuk O. A dual role of miR-22 modulated by RelA/p65 in resensitizing fulvestrant-resistant breast cancer cells to fulvestrant by targeting FOXP1 and HDAC4 and constitutive acetylation of p53 at Lys382. Oncogenesis. 7: 54. PMID 30057418 DOI: 10.1038/s41389-018-0063-5  0.36
2018 Wang B, Li D, Kovalchuk I, Apel IJ, Chinnaiyan AM, Wóycicki RK, Cantor CR, Kovalchuk O. miR-34a directly targets tRNA precursors and affects cellular proliferation, cell cycle, and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29941603 DOI: 10.1073/pnas.1703029115  0.96
2018 Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Katz A, Sidransky D, Kolb B, Kovalchuk O. Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice-an Aging Connection. Frontiers in Genetics. 9: 58. PMID 29556248 DOI: 10.3389/fgene.2018.00058  0.44
2018 Kovalchuk A, Ilnytskyy Y, Woycicki R, Rodriguez-Juarez R, Metz GAS, Kovalchuk O. Adverse effects of paternal chemotherapy exposure on the progeny brain: intergenerational chemobrain. Oncotarget. 9: 10069-10082. PMID 29515791 DOI: 10.18632/oncotarget.24311  0.68
2018 Mamoshina P, Kochetov K, Putin E, Cortese F, Aliper A, Lee WS, Ahn SM, Uhn L, Skjodt N, Kovalchuk O, Scheibye-Knudsen M, Zhavoronkov A. Population specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern European patient populations. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29340580 DOI: 10.1093/gerona/gly005  0.36
2018 Borisov N, Tkachev V, Suntsova M, Kovalchuk O, Zhavoronkov A, Muchnik I, Buzdin A. A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency. Cell Cycle (Georgetown, Tex.). 1-6. PMID 29251172 DOI: 10.1080/15384101.2017.1417706  0.4
2017 Byeon B, Bilichak A, Kovalchuk I. Computational Characterization of ncRNA Fragments in Various Tissues of the Brassica rapa Plant. Non-Coding Rna. 3. PMID 29657288 DOI: 10.3390/ncrna3020017  0.68
2017 Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Katz A, Sidransky D, Kolb B, Kovalchuk O. Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice. Oncotarget. 8: 88276-88293. PMID 29179434 DOI: 10.18632/oncotarget.19835  0.4
2017 Petrov I, Suntsova M, Ilnitskaya E, Roumiantsev S, Sorokin M, Garazha A, Spirin P, Lebedev T, Gaifullin N, Larin S, Kovalchuk O, Konovalov D, Prassolov V, Roumiantsev A, Buzdin A. Gene expression and molecular pathway activation signatures of MYCN-amplified neuroblastomas. Oncotarget. 8: 83768-83780. PMID 29137381 DOI: 10.18632/oncotarget.19662  0.32
2017 Sidler C, Kovalchuk O, Kovalchuk I. Epigenetic Regulation of Cellular Senescence and Aging. Frontiers in Genetics. 8: 138. PMID 29018479 DOI: 10.3389/fgene.2017.00138  0.96
2017 Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Shpyleva S, Melnyk S, Pogribny I, Katz A, Sidransky D, Kovalchuk O, Kolb B. Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice. Aging. 9: 1660-1676. PMID 28758896 DOI: 10.18632/aging.101243  0.36
2017 Gerrard B, Singh V, Babenko O, Gauthier I, Wee Yong V, Kovalchuk I, Luczak A, Metz GAS. Chronic Mild Stress Exacerbates Severity of Experimental Autoimmune Encephalomyelitis in Association with Altered Non-coding RNA and Metabolic Biomarkers. Neuroscience. PMID 28739526 DOI: 10.1016/j.neuroscience.2017.07.033  0.84
2017 Faraji J, Soltanpour N, Ambeskovic M, Zucchi FCR, Beaumier P, Kovalchuk I, Metz GAS. Evidence for Ancestral Programming of Resilience in a Two-Hit Stress Model. Frontiers in Behavioral Neuroscience. 11: 89. PMID 28553212 DOI: 10.3389/fnbeh.2017.00089  0.6
2017 Moskalev A, Anisimov V, Aliper A, Artemov A, Asadullah K, Belsky D, Baranova A, de Grey A, Dixit VD, Debonneuil E, Dobrovolskaya E, Fedichev P, Fedintsev A, Fraifeld V, Franceschi C, ... ... Kovalchuk I, et al. A review of the biomedical innovations for healthy longevity. Aging. PMID 28132958 DOI: 10.18632/aging.101163  0.96
2017 Bilichak A, Kovalchuk I. The Random Oligonucleotide-Primed Synthesis Assay for the Quantification of DNA Strand Breaks. Methods in Molecular Biology (Clifton, N.J.). 1456: 237-242. PMID 27770370 DOI: 10.1007/978-1-4899-7708-3_18  0.68
2017 Bilichak A, Kovalchuk I. Increasing a Stable Transformation Efficiency of Arabidopsis by Manipulating the Endogenous Gene Expression Using Virus-Induced Gene Silencing. Methods in Molecular Biology (Clifton, N.J.). 1456: 225-236. PMID 27770369 DOI: 10.1007/978-1-4899-7708-3_17  0.68
2017 Bilichak A, Golubov A, Kovalchuk I. Small RNA Library Preparation and Illumina Sequencing in Plants. Methods in Molecular Biology (Clifton, N.J.). 1456: 189-196. PMID 27770367 DOI: 10.1007/978-1-4899-7708-3_15  0.8
2017 Golubov A, Kovalchuk I. Analysis of DNA Hydroxymethylation Using Colorimetric Assay. Methods in Molecular Biology (Clifton, N.J.). 1456: 89-97. PMID 27770360 DOI: 10.1007/978-1-4899-7708-3_8  0.8
2017 Kathiria P, Kovalchuk I. In Situ Analysis of DNA Methylation in Plants. Methods in Molecular Biology (Clifton, N.J.). 1456: 81-88. PMID 27770359 DOI: 10.1007/978-1-4899-7708-3_7  0.68
2017 Bilichak A, Kovalchuk I. Analysis of Global Genome Methylation Using the Cytosine-Extension Assay. Methods in Molecular Biology (Clifton, N.J.). 1456: 73-79. PMID 27770358 DOI: 10.1007/978-1-4899-7708-3_6  0.68
2017 Bilichak A, Kovalchuk I. The Combined Bisulfite Restriction Analysis (COBRA) Assay for the Analysis of Locus-Specific Changes in Methylation Patterns. Methods in Molecular Biology (Clifton, N.J.). 1456: 63-71. PMID 27770357 DOI: 10.1007/978-1-4899-7708-3_5  0.68
2016 Koturbash I, Jadavji NM, Kutanzi K, Rodriguez-Juarez R, Kogosov D, Metz GAS, Kovalchuk O. Fractionated low-dose exposure to ionizing radiation leads to DNA damage, epigenetic dysregulation, and behavioral impairment. Environmental Epigenetics. 2: dvw025. PMID 29492301 DOI: 10.1093/eep/dvw025  0.64
2016 Buzdin AA, Artcibasova AV, Fedorova NF, Suntsova MV, Garazha AV, Sorokin MI, Allina D, Shalatonin M, Borisov NM, Zhavoronkov AA, Kovalchuk I, Kovalchuk O, Kushch AA. Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts. Cell Cycle (Georgetown, Tex.). 15: 3378-3389. PMID 28051642 DOI: 10.1080/15384101.2016.1241928  0.96
2016 McCreary JK, Erickson ZT, Hao Y, Ilnytskyy Y, Kovalchuk I, Metz GA. Environmental Intervention as a Therapy for Adverse Programming by Ancestral Stress. Scientific Reports. 6: 37814. PMID 27883060 DOI: 10.1038/srep37814  0.88
2016 Petrov I, Suntsova M, Mutorova O, Sorokin M, Garazha A, Ilnitskaya E, Spirin P, Larin S, Kovalchuk O, Prassolov V, Zhavoronkov A, Roumiantsev A, Buzdin A. Molecular pathway activation features of pediatric acute myeloid leukemia (AML) and acute lymphoblast leukemia (ALL) cells. Aging. PMID 27870639 DOI: 10.18632/aging.101102  0.32
2016 Byeon B, Kovalchuk I. Non-coding RNAs match the deleted genomic regions in humans. Scientific Reports. 6: 37452. PMID 27853310 DOI: 10.1038/srep37452  0.64
2016 Koturbash I, Merrifield M, Kovalchuk O. Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner. International Journal of Radiation Biology. 1-8. PMID 27758128 DOI: 10.1080/09553002.2017.1231943  0.48
2016 Luzhna L, Kovalchuk O. Mammary gland and radiation: Knowns and unknowns. Cell Cycle (Georgetown, Tex.). 1-2. PMID 27392129 DOI: 10.1080/15384101.2016.1170262  1
2016 Byeon B, Kovalchuk I. Pattern Recognition on Read Positioning in Next Generation Sequencing. Plos One. 11: e0157033. PMID 27299343 DOI: 10.1371/journal.pone.0157033  0.64
2016 Keiko McCreary J, Sorina Truica L, Friesen B, Yao Y, Olson DM, Kovalchuk I, Cross AR, Metz GA. Altered Brain Morphology and Functional Connectivity Reflect a Vulnerable Affective State after Cumulative Multigenerational Stress in Rats. Neuroscience. PMID 27241944 DOI: 10.1016/j.neuroscience.2016.05.046  0.84
2016 Luzhna L, Filkowski J, Kovalchuk O. High and low dose radiation effects on mammary adenocarcinoma cells - an epigenetic connection. Oncoscience. 3: 88-97. PMID 27226982 DOI: 10.18632/oncoscience.298  0.92
2016 Kovalchuk A, Rodriguez-Juarez R, Ilnytskyy Y, Byeon B, Shpyleva S, Melnyk S, Pogribny I, Kolb B, Kovalchuk O. Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection. Aging. 8: 697-711. PMID 27032448 DOI: 10.18632/aging.100920  0.36
2016 Kochan DZ, Ilnytskyy Y, Golubov A, Deibel SH, McDonald RJ, Kovalchuk O. Circadian-disruption-induced gene expression changes in rodent mammary tissues. Oncoscience. 3: 58-70. PMID 27014724  0.68
2016 Maheshwari P, Kovalchuk I. Agrobacterium-Mediated Stable Genetic Transformation of Populus angustifolia and Populus balsamifera. Frontiers in Plant Science. 7: 296. PMID 27014319 DOI: 10.3389/fpls.2016.00296  0.84
2016 Bilichak A, Kovalchuk I. Transgenerational response to stress in plants and its application for breeding. Journal of Experimental Botany. 67: 2081-92. PMID 26944635 DOI: 10.1093/jxb/erw066  0.68
2016 Yao Y, Bilichak A, Golubov A, Kovalchuk I. Arabidopsis thaliana siRNA biogenesis mutants have the lower frequency of homologous recombination. Plant Signaling & Behavior. 0. PMID 26901311 DOI: 10.1080/15592324.2016.1151599  0.92
2016 Kochan DZ, Kovalchuk O. Circadian disruption-induced breast cancer - knowns and unknowns. Cell Cycle (Georgetown, Tex.). 15: 613-4. PMID 26735780 DOI: 10.1080/15384101.2015.1131526  0.96
2015 Heyns M, Kovalchuk O. Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer. Oncotarget. 6: 23055-7. PMID 26405161 DOI: 10.18632/oncotarget.5048  0.52
2015 Kochan DZ, Kovalchuk O. Circadian disruption and breast cancer: an epigenetic link? Oncotarget. 6: 16866-82. PMID 26220712 DOI: 10.18632/oncotarget.4343  0.96
2015 Kochan DZ, Ilnytskyy Y, Golubov A, Deibel SH, McDonald RJ, Kovalchuk O. Circadian disruption-induced microRNAome deregulation in rat mammary gland tissues. Oncoscience. 2: 428-42. PMID 26097876 DOI: 10.18632/oncoscience.157  0.68
2015 Wang B, Li D, Sidler C, Rodriguez-Juarez R, Singh N, Heyns M, Ilnytskyy Y, Bronson RT, Kovalchuk O. A suppressive role of ionizing radiation-responsive miR-29c in the development of liver carcinoma via targeting WIP1. Oncotarget. 6: 9937-50. PMID 25888625  0.36
2015 Luzhna L, Ilnytskyy Y, Kovalchuk O. Mobilization of LINE-1 in irradiated mammary gland tissue may potentially contribute to low dose radiation-induced genomic instability. Genes & Cancer. 6: 71-81. PMID 25821563 DOI: 10.18632/genesandcancer.50  0.96
2015 Luzhna L, Kutanzi K, Kovalchuk O. Gene expression and epigenetic profiles of mammary gland tissue: insight into the differential predisposition of four rat strains to mammary gland cancer. Mutation Research. Genetic Toxicology and Environmental Mutagenesis. 779: 39-56. PMID 25813725 DOI: 10.1016/j.mrgentox.2014.07.006  0.76
2015 Metz GA, Ng JW, Kovalchuk I, Olson DM. Ancestral experience as a game changer in stress vulnerability and disease outcomes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 602-11. PMID 25759985 DOI: 10.1002/bies.201400217  0.84
2015 Luzhna L, Lykkesfeldt AE, Kovalchuk O. Altered radiation responses of breast cancer cells resistant to hormonal therapy. Oncotarget. 6: 1678-94. PMID 25682200 DOI: 10.18632/oncotarget.3188  0.92
2015 Bilichak A, Ilnytskyy Y, Wóycicki R, Kepeshchuk N, Fogen D, Kovalchuk I. The elucidation of stress memory inheritance in Brassica rapa plants. Frontiers in Plant Science. 6: 5. PMID 25653665 DOI: 10.3389/fpls.2015.00005  0.88
2015 Sidler C, Li D, Kovalchuk O, Kovalchuk I. Development-dependent expression of DNA repair genes and epigenetic regulators in Arabidopsis plants exposed to ionizing radiation. Radiation Research. 183: 219-32. PMID 25594540 DOI: 10.1667/RR13840.1  0.96
2015 Babenko O, Kovalchuk I, Metz GA. Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health. Neuroscience and Biobehavioral Reviews. 48: 70-91. PMID 25464029 DOI: 10.1016/j.neubiorev.2014.11.013  0.84
2014 Luzhna L, Kovalchuk O. Low dose irradiation profoundly affects transcriptome and microRNAme in rat mammary gland tissues. Oncoscience. 1: 751-62. PMID 25594002 DOI: 10.18632/oncoscience.94  0.96
2014 Sidler C, Li D, Wang B, Kovalchuk I, Kovalchuk O. SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation. Frontiers in Genetics. 5: 411. PMID 25484892 DOI: 10.3389/fgene.2014.00411  0.96
2014 Migicovsky Z, Kovalchuk I. Transgenerational changes in plant physiology and in transposon expression in response to UV-C stress in Arabidopsis thaliana. Plant Signaling & Behavior. 9: e976490. PMID 25482751 DOI: 10.4161/15592324.2014.976490  0.68
2014 Kovalchuk IP, Golubov A, Koturbash IV, Kutanzi K, Martin OA, Kovalchuk O. Age-dependent changes in DNA repair in radiation-exposed mice. Radiation Research. 182: 683-94. PMID 25409128 DOI: 10.1667/RR13697.1  0.84
2014 Lezhnina K, Kovalchuk O, Zhavoronkov AA, Korzinkin MB, Zabolotneva AA, Shegay PV, Sokov DG, Gaifullin NM, Rusakov IG, Aliper AM, Roumiantsev SA, Alekseev BY, Borisov NM, Buzdin AA. Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways. Oncotarget. 5: 9022-32. PMID 25296972 DOI: 10.18632/oncotarget.2493  0.48
2014 Yao Y, Robinson AM, Zucchi FC, Robbins JC, Babenko O, Kovalchuk O, Kovalchuk I, Olson DM, Metz GA. Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes. Bmc Medicine. 12: 121. PMID 25286408 DOI: 10.1186/s12916-014-0121-6  0.84
2014 Sidler C, Woycicki R, Kovalchuk I, Kovalchuk O. WI-38 senescence is associated with global and site-specific hypomethylation. Aging. 6: 564-74. PMID 25063771 DOI: 10.18632/aging.100679  0.96
2014 Sidler C, Woycicki R, Li D, Wang B, Kovalchuk I, Kovalchuk O. A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts. Aging. 6: 545-63. PMID 25063769 DOI: 10.18632/aging.100678  0.96
2014 Wang B, Li D, Kovalchuk A, Litvinov D, Kovalchuk O. Ionizing radiation-inducible miR-27b suppresses leukemia proliferation via targeting cyclin A2. International Journal of Radiation Oncology, Biology, Physics. 90: 53-62. PMID 24974217 DOI: 10.1016/j.ijrobp.2014.04.055  0.4
2014 Zucchi FC, Yao Y, Ilnytskyy Y, Robbins JC, Soltanpour N, Kovalchuk I, Kovalchuk O, Metz GA. Lifetime stress cumulatively programs brain transcriptome and impedes stroke recovery: benefit of sensory stimulation. Plos One. 9: e92130. PMID 24651125 DOI: 10.1371/journal.pone.0092130  0.84
2014 Bilichak A, Yao Y, Titov V, Golubov A, Kovalchuk I. Genome stability in the uvh6 mutant of Arabidopsis thaliana. Plant Cell Reports. 33: 979-91. PMID 24553752 DOI: 10.1007/s00299-014-1580-0  0.92
2014 Migicovsky Z, Yao Y, Kovalchuk I. Transgenerational phenotypic and epigenetic changes in response to heat stress in Arabidopsis thaliana. Plant Signaling & Behavior. 9: e27971. PMID 24513700  0.92
2014 Kovalchuk O, Walz P, Kovalchuk I. Does bacterial infection cause genome instability and cancer in the host cell? Mutation Research. 761: 1-14. PMID 24472301 DOI: 10.1016/j.mrfmmm.2014.01.004  0.96
2014 Bilichak A, Yao Y, Kovalchuk I. Transient down-regulation of the RNA silencing machinery increases efficiency of Agrobacterium-mediated transformation of Arabidopsis. Plant Biotechnology Journal. 12: 590-600. PMID 24472037 DOI: 10.1111/pbi.12165  0.92
2014 Zucchi F, Yao Y, Ilnytskyy Y, Robbins JC, Soltanpour N. Correction: Lifetime stress cumulatively programs brain transcriptome and impedes stroke recovery: Benefit of sensory stimulation (PLoS ONE (2014) 9, 3 (e92130) DOI: 10.1371/journal.pone.0092130) Plos One. 9. DOI: 10.1371/journal.pone.0102489  0.48
2014 Titova LV, Ayesheshim AK, Purschke D, Golubov A, Rodriguez-Juarez R, Woycicki R, Hegmann FA, Kovalchuk O. Effect of intense THz pulses on expression of genes associated with skin cancer and inflammatory skin conditions Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8941. DOI: 10.1117/12.2044167  0.72
2013 Sidler C, Wóycicki R, Ilnytskyy Y, Metz G, Kovalchuk I, Kovalchuk O. Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs. Frontiers in Genetics. 4: 211. PMID 24151501 DOI: 10.3389/fgene.2013.00211  0.96
2013 Li D, Ilnytskyy Y, Kovalchuk A, Khachigian LM, Bronson RT, Wang B, Kovalchuk O. Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer. Oncotarget. 4: 1373-87. PMID 23945289 DOI: 10.18632/oncotarget.1165  0.32
2013 Titova LV, Ayesheshim AK, Golubov A, Rodriguez-Juarez R, Woycicki R, Hegmann FA, Kovalchuk O. Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? Scientific Reports. 3: 2363. PMID 23917523 DOI: 10.1038/srep02363  0.52
2013 Kovalchuk A, Aladedunye F, Rodriguez-Juarez R, Li D, Thomas J, Kovalchuk O, Przybylski R. Novel antioxidants are not toxic to normal tissues but effectively kill cancer cells. Cancer Biology & Therapy. 14: 907-15. PMID 23917379 DOI: 10.4161/cbt.25935  0.6
2013 Kovalchuk I, Walz P, Thomas J, Kovalchuk O. Genomic instability in liver cells caused by an LPS-induced bystander-like effect. Plos One. 8: e67342. PMID 23874414 DOI: 10.1371/journal.pone.0067342  0.96
2013 Luzhna L, Kathiria P, Kovalchuk O. Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond. Frontiers in Genetics. 4: 131. PMID 23874352 DOI: 10.3389/fgene.2013.00131  0.84
2013 Kovalchuk I, Walz P, Thomas J, Kovalchuk O. The increased expression of proteins involved in proliferation, DNA repair and DNA methylation in spleen of mice exposed to E. coli O157:H7 lipopolysaccharide. Environmental and Molecular Mutagenesis. 54: 421-8. PMID 23813549 DOI: 10.1002/em.21787  0.96
2013 Kutanzi K, Kovalchuk O. Exposure to estrogen and ionizing radiation causes epigenetic dysregulation, activation of mitogen-activated protein kinase pathways, and genome instability in the mammary gland of ACI rats. Cancer Biology & Therapy. 14: 564-73. PMID 23792640 DOI: 10.4161/cbt.24599  0.84
2013 Wang B, Li D, Kovalchuk O. p53 Ser15 phosphorylation and histone modifications contribute to IR-induced miR-34a transcription in mammary epithelial cells. Cell Cycle (Georgetown, Tex.). 12: 2073-83. PMID 23759592 DOI: 10.4161/cc.25135  0.44
2013 Kathiria P, Sidler C, Woycicki R, Yao Y, Kovalchuk I. Effect of external and internal factors on the expression of reporter genes driven by the N resistance gene promoter. Plant Signaling & Behavior. 8: e24760. PMID 23656874 DOI: 10.4161/psb.24760  0.92
2013 Kirkby C, Ghasroddashti E, Kovalchuk A, Kolb B, Kovalchuk O. Monte Carlo-based dose reconstruction in a rat model for scattered ionizing radiation investigations. International Journal of Radiation Biology. 89: 741-9. PMID 23593950 DOI: 10.3109/09553002.2013.791407  0.48
2013 Titova LV, Ayesheshim AK, Golubov A, Fogen D, Rodriguez-Juarez R, Hegmann FA, Kovalchuk O. Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue. Biomedical Optics Express. 4: 559-68. PMID 23577291 DOI: 10.1364/BOE.4.000559  0.48
2013 Merrifield M, Kovalchuk O. Epigenetics in radiation biology: a new research frontier. Frontiers in Genetics. 4: 40. PMID 23577019 DOI: 10.3389/fgene.2013.00040  0.44
2013 Yao Y, Bilichak A, Titov V, Golubov A, Kovalchuk I. Genome stability of Arabidopsis atm, ku80 and rad51b mutants: somatic and transgenerational responses to stress. Plant & Cell Physiology. 54: 982-9. PMID 23574700 DOI: 10.1093/pcp/pct051  0.92
2013 Yao Y, Kathiria P, Kovalchuk I. A systemic increase in the recombination frequency upon local infection of Arabidopsis thaliana plants with oilseed rape mosaic virus depends on plant age, the initial inoculum concentration and the time for virus replication. Frontiers in Plant Science. 4: 61. PMID 23519399 DOI: 10.3389/fpls.2013.00061  0.92
2013 Luzhna L, Golubov A, Ilnytskyy S, Chekhun VF, Kovalchuk O. Molecular mechanisms of radiation resistance in doxorubicin-resistant breast adenocarcinoma cells. International Journal of Oncology. 42: 1692-708. PMID 23467667 DOI: 10.3892/ijo.2013.1845  0.68
2013 Zucchi FC, Yao Y, Ward ID, Ilnytskyy Y, Olson DM, Benzies K, Kovalchuk I, Kovalchuk O, Metz GA. Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring. Plos One. 8: e56967. PMID 23451123 DOI: 10.1371/journal.pone.0056967  0.84
2013 Migicovsky Z, Kovalchuk I. Changes to DNA methylation and homologous recombination frequency in the progeny of stressed plants. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 91: 1-5. PMID 23442135 DOI: 10.1139/bcb-2012-0046  0.68
2013 Koch MW, Metz LM, Kovalchuk O. Epigenetic changes in patients with multiple sclerosis. Nature Reviews. Neurology. 9: 35-43. PMID 23165337 DOI: 10.1038/nrneurol.2012.226  0.32
2013 Zabolotneva AA, Zhavoronkov AA, Shegay PV, Gaifullin NM, Alekseev BY, Roumiantsev SA, Garazha AV, Kovalchuk O, Aravin A, Buzdin AA. A systematic experimental evaluation of microRNA markers of human bladder cancer Frontiers in Genetics. 4. DOI: 10.3389/fgene.2013.00247  0.68
2012 Yao Y, Danna CH, Ausubel FM, Kovalchuk I. Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants. Plant Signaling & Behavior. 7: 741-5. PMID 22751319 DOI: 10.4161/psb.20406  0.84
2012 Zemp FJ, Sidler C, Kovalchuk I. Increase in recombination rate in Arabidopsis thaliana plants sharing gaseous environment with X-ray and UVC-irradiated plants depends on production of radicals. Plant Signaling & Behavior. 7: 782-7. PMID 22751301 DOI: 10.4161/psb.20571  0.68
2012 Migicovsky Z, Kovalchuk I. Epigenetic Modifications during Angiosperm Gametogenesis. Frontiers in Plant Science. 3: 20. PMID 22645573 DOI: 10.3389/fpls.2012.00020  0.68
2012 Yao Y, Bilichak A, Golubov A, Kovalchuk I. ddm1 plants are sensitive to methyl methane sulfonate and NaCl stresses and are deficient in DNA repair. Plant Cell Reports. 31: 1549-61. PMID 22538524 DOI: 10.1007/s00299-012-1269-1  0.92
2012 Kovalchuk A, Lowings M, Rodriguez-Juarez R, Muhammad A, Ilnytskyy S, Kolb B, Kovalchuk O. Epigenetic bystander-like effects of stroke in somatic organs. Aging. 4: 224-34. PMID 22466454  0.48
2012 Babenko O, Kovalchuk I, Metz GA. Epigenetic programming of neurodegenerative diseases by an adverse environment. Brain Research. 1444: 96-111. PMID 22330722 DOI: 10.1016/j.brainres.2012.01.038  0.84
2012 Bilichak A, Ilnystkyy Y, Hollunder J, Kovalchuk I. The progeny of Arabidopsis thaliana plants exposed to salt exhibit changes in DNA methylation, histone modifications and gene expression. Plos One. 7: e30515. PMID 22291972 DOI: 10.1371/journal.pone.0030515  0.68
2012 Babenko O, Golubov A, Ilnytskyy Y, Kovalchuk I, Metz GA. Genomic and epigenomic responses to chronic stress involve miRNA-mediated programming. Plos One. 7: e29441. PMID 22291890 DOI: 10.1371/journal.pone.0029441  0.84
2012 Ziemienowicz A, Shim YS, Matsuoka A, Eudes F, Kovalchuk I. A novel method of transgene delivery into triticale plants using the Agrobacterium transferred DNA-derived nano-complex. Plant Physiology. 158: 1503-13. PMID 22291201 DOI: 10.1104/pp.111.192856  0.84
2011 Rahavi MR, Migicovsky Z, Titov V, Kovalchuk I. Transgenerational adaptation to heavy metal salts in Arabidopsis. Frontiers in Plant Science. 2: 91. PMID 22639617 DOI: 10.3389/fpls.2011.00091  0.68
2011 Migicovsky Z, Kovalchuk I. Epigenetic memory in mammals. Frontiers in Genetics. 2: 28. PMID 22303324 DOI: 10.3389/fgene.2011.00028  0.68
2011 Yao Y, Danna CH, Zemp FJ, Titov V, Ciftci ON, Przybylski R, Ausubel FM, Kovalchuk I. UV-C-irradiated Arabidopsis and tobacco emit volatiles that trigger genomic instability in neighboring plants. The Plant Cell. 23: 3842-52. PMID 22028460 DOI: 10.1105/tpc.111.089003  0.84
2011 Dickey JS, Zemp FJ, Martin OA, Kovalchuk O. The role of miRNA in the direct and indirect effects of ionizing radiation. Radiation and Environmental Biophysics. 50: 491-9. PMID 21928045 DOI: 10.1007/s00411-011-0386-5  0.4
2011 Mychasiuk R, Schmold N, Ilnytskyy S, Kovalchuk O, Kolb B, Gibb R. Prenatal bystander stress alters brain, behavior, and the epigenome of developing rat offspring. Developmental Neuroscience. 33: 159-69. PMID 21893948 DOI: 10.1159/000330034  0.36
2011 Ilnytskyy Y, Kovalchuk O. Non-targeted radiation effects-an epigenetic connection. Mutation Research. 714: 113-25. PMID 21784089 DOI: 10.1016/j.mrfmmm.2011.06.014  0.92
2011 Maheshwari P, Selvaraj G, Kovalchuk I. Optimization of Brassica napus (canola) explant regeneration for genetic transformation. New Biotechnology. 29: 144-55. PMID 21722759 DOI: 10.1016/j.nbt.2011.06.014  0.84
2011 Hudson D, Kovalchuk I, Koturbash I, Kolb B, Martin OA, Kovalchuk O. Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals. Aging. 3: 609-20. PMID 21685513  0.84
2011 Maheshwari P, Kovalchuk I. Efficient shoot regeneration from internodal explants of Populus angustifolia, Populus balsamifera and Populus deltoids. New Biotechnology. 28: 778-87. PMID 21640207 DOI: 10.1016/j.nbt.2011.05.005  0.84
2011 Boyko A, Kovalchuk I. Genetic and epigenetic effects of plant-pathogen interactions: an evolutionary perspective. Molecular Plant. 4: 1014-23. PMID 21459830 DOI: 10.1093/mp/ssr022  0.44
2011 Boyko A, Kovalchuk I. Genome instability and epigenetic modification--heritable responses to environmental stress? Current Opinion in Plant Biology. 14: 260-6. PMID 21440490 DOI: 10.1016/j.pbi.2011.03.003  0.44
2011 Yao Y, Bilichak A, Golubov A, Kovalchuk I. Local infection with oilseed rape mosaic virus promotes genetic rearrangements in systemic Arabidopsis tissue. Mutation Research. 709: 7-14. PMID 21376739 DOI: 10.1016/j.mrfmmm.2011.02.014  0.92
2011 Yao Y, Kovalchuk I. Abiotic stress leads to somatic and heritable changes in homologous recombination frequency, point mutation frequency and microsatellite stability in Arabidopsis plants. Mutation Research. 707: 61-6. PMID 21236268 DOI: 10.1016/j.mrfmmm.2010.12.013  0.92
2011 Tamminga J, Kovalchuk O. Role of DNA damage and epigenetic DNA methylation changes in radiation-induced genomic instability and bystander effects in germline in vivo. Current Molecular Pharmacology. 4: 115-25. PMID 21143184  0.8
2011 Boyko A, Matsuoka A, Kovalchuk I. Potassium chloride and rare earth elements improve plant growth and increase the frequency of the Agrobacterium tumefaciens-mediated plant transformation. Plant Cell Reports. 30: 505-18. PMID 21132499 DOI: 10.1007/s00299-010-0960-3  0.44
2011 Koturbash I, Zemp F, Kolb B, Kovalchuk O. Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 722: 114-118. PMID 20478395 DOI: 10.1016/j.mrgentox.2010.05.007  0.48
2011 Koturbash I, Zemp FJ, Pogribny I, Kovalchuk O. Small molecules with big effects: the role of the microRNAome in cancer and carcinogenesis. Mutation Research. 722: 94-105. PMID 20472093 DOI: 10.1016/j.mrgentox.2010.05.006  0.68
2011 Shpyleva SI, Tryndyak VP, Kovalchuk O, Starlard-Davenport A, Chekhun VF, Beland FA, Pogribny IP. Role of ferritin alterations in human breast cancer cells. Breast Cancer Research and Treatment. 126: 63-71. PMID 20390345 DOI: 10.1007/s10549-010-0849-4  0.32
2010 Yao Y, Bilichak A, Golubov A, Blevins T, Kovalchuk I. Differential sensitivity of Arabidopsis siRNA biogenesis mutants to genotoxic stress. Plant Cell Reports. 29: 1401-10. PMID 20953786 DOI: 10.1007/s00299-010-0930-9  0.92
2010 Golubov A, Yao Y, Maheshwari P, Bilichak A, Boyko A, Belzile F, Kovalchuk I. Microsatellite instability in Arabidopsis increases with plant development. Plant Physiology. 154: 1415-27. PMID 20817752 DOI: 10.1104/pp.110.162933  0.84
2010 Boyko A, Kovalchuk I. Transgenerational response to stress in Arabidopsis thaliana. Plant Signaling & Behavior. 5: 995-8. PMID 20724818 DOI: 10.1371/journal.pone.0009514  0.44
2010 Kutanzi KR, Koturbash I, Kovalchuk O. Reversibility of pre-malignant estrogen-induced epigenetic changes. Cell Cycle (Georgetown, Tex.). 9: 3078-84. PMID 20699652 DOI: 10.4161/cc.9.15.12516  0.48
2010 Kutanzi KR, Koturbash I, Bronson RT, Pogribny IP, Kovalchuk O. Imbalance between apoptosis and cell proliferation during early stages of mammary gland carcinogenesis in ACI rats. Mutation Research. 694: 1-6. PMID 20659487 DOI: 10.1016/j.mrfmmm.2010.07.006  0.44
2010 Kovalchuk O, Zemp FJ, Filkowski JN, Altamirano AM, Dickey JS, Jenkins-Baker G, Marino SA, Brenner DJ, Bonner WM, Sedelnikova OA. microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways. Carcinogenesis. 31: 1882-8. PMID 20643754 DOI: 10.1093/carcin/bgq119  0.4
2010 Kathiria P, Sidler C, Golubov A, Kalischuk M, Kawchuk LM, Kovalchuk I. Tobacco mosaic virus infection results in an increase in recombination frequency and resistance to viral, bacterial, and fungal pathogens in the progeny of infected tobacco plants. Plant Physiology. 153: 1859-70. PMID 20498336 DOI: 10.1104/pp.110.157263  0.8
2010 Boyko A, Golubov A, Bilichak A, Kovalchuk I. Chlorine ions but not sodium ions alter genome stability of Arabidopsis thaliana. Plant & Cell Physiology. 51: 1066-78. PMID 20385609 DOI: 10.1093/pcp/pcq048  0.8
2010 Boyko A, Blevins T, Yao Y, Golubov A, Bilichak A, Ilnytskyy Y, Hollunder J, Hollander J, Meins F, Kovalchuk I. Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins. Plos One. 5: e9514. PMID 20209086 DOI: 10.1371/journal.pone.0009514  0.92
2010 Kathiria P, Kovalchuk I. Reporter gene-based recombination lines for studies of genome stability. Methods in Molecular Biology (Clifton, N.J.). 631: 243-52. PMID 20204880 DOI: 10.1007/978-1-60761-646-7_18  0.68
2010 Boyko A, Kovalchuk I. Detection and quantification of DNA strand breaks using the ROPS (random oligonucleotide primed synthesis) assay. Methods in Molecular Biology (Clifton, N.J.). 631: 237-42. PMID 20204879 DOI: 10.1007/978-1-60761-646-7_17  0.44
2010 Boyko A, Kovalchuk I. Analysis of mutation/rearrangement frequencies and methylation patterns at a given DNA locus using restriction fragment length polymorphism. Methods in Molecular Biology (Clifton, N.J.). 631: 49-62. PMID 20204868 DOI: 10.1007/978-1-60761-646-7_6  0.44
2010 Kathiria P, Kovalchuk I. In situ analysis of DNA methylation in plants. Methods in Molecular Biology (Clifton, N.J.). 631: 41-8. PMID 20204867 DOI: 10.1007/978-1-60761-646-7_5  0.68
2010 Boyko A, Kovalchuk I. Detection of changes in global genome methylation using the cytosine-extension assay. Methods in Molecular Biology (Clifton, N.J.). 631: 33-9. PMID 20204866 DOI: 10.1007/978-1-60761-646-7_4  0.44
2010 Boyko A, Kovalchuk I. Analysis of locus-specific changes in methylation patterns using a COBRA (combined bisulfite restriction analysis) assay. Methods in Molecular Biology (Clifton, N.J.). 631: 23-31. PMID 20204865 DOI: 10.1007/978-1-60761-646-7_3  0.44
2010 Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI, Kovalchuk O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. International Journal of Cancer. 127: 1785-94. PMID 20099276 DOI: 10.1002/ijc.25191  0.48
2010 Luzhna L, Kovalchuk O. Modulation of DNA methylation levels sensitizes doxorubicin-resistant breast adenocarcinoma cells to radiation-induced apoptosis. Biochemical and Biophysical Research Communications. 392: 113-7. PMID 20034463 DOI: 10.1016/j.bbrc.2009.12.093  0.92
2010 Filkowski JN, Ilnytskyy Y, Tamminga J, Koturbash I, Golubov A, Bagnyukova T, Pogribny IP, Kovalchuk O. Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression. Carcinogenesis. 31: 1110-5. PMID 19959559 DOI: 10.1093/carcin/bgp300  0.52
2010 Boyko A, Molinier J, Chatter W, Laroche A, Kovalchuk I. Acute but not chronic exposure to abiotic stress results in transient reduction of expression levels of the transgene driven by the 35S promoter. New Biotechnology. 27: 70-7. PMID 19800040 DOI: 10.1016/j.nbt.2009.09.007  0.84
2009 Koturbash I, Thomas JE, Kovalchuk O, Kovalchuk I. Heat-killed bacteria induce genome instability in mouse small intestine, liver and spleen tissues. Cell Cycle (Georgetown, Tex.). 8: 1935-9. PMID 19440049  0.96
2009 Boyko A, Matsuoka A, Kovalchuk I. High frequency Agrobacterium tumefaciens-mediated plant transformation induced by ammonium nitrate. Plant Cell Reports. 28: 737-57. PMID 19221758 DOI: 10.1007/s00299-009-0676-4  0.44
2009 Ilnytskyy Y, Koturbash I, Kovalchuk O. Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner. Environmental and Molecular Mutagenesis. 50: 105-13. PMID 19107897 DOI: 10.1002/em.20440  0.64
2008 Kovalchuk I, Kovalchuk O. Transgenic Plants as Sensors of Environmental Pollution Genotoxicity. Sensors (Basel, Switzerland). 8: 1539-1558. PMID 27879779 DOI: 10.3390/s8031539  0.96
2008 Tamminga J, Kathiria P, Koturbash I, Kovalchuk O. DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle (Georgetown, Tex.). 7: 3731-6. PMID 19029807 DOI: 10.4161/cc.7.23.7186  0.72
2008 Ilnytskyy Y, Zemp FJ, Koturbash I, Kovalchuk O. Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochemical and Biophysical Research Communications. 377: 41-5. PMID 18823940 DOI: 10.1016/j.bbrc.2008.09.080  0.68
2008 Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF, Pogribny IP. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Molecular Cancer Therapeutics. 7: 2152-9. PMID 18645025 DOI: 10.1158/1535-7163.MCT-08-0021  0.36
2008 Koturbash I, Zemp FJ, Kutanzi K, Luzhna L, Loree J, Kolb B, Kovalchuk O. Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice Cell Cycle. 7: 1658-1667. PMID 18560276  0.56
2008 Koturbash I, Kutanzi K, Hendrickson K, Rodriguez-Juarez R, Kogosov D, Kovalchuk O. Radiation-induced bystander effects in vivo are sex specific. Mutation Research. 642: 28-36. PMID 18508093 DOI: 10.1016/j.mrfmmm.2008.04.002  0.64
2008 Tamminga J, Koturbash I, Baker M, Kutanzi K, Kathiria P, Pogribny IP, Sutherland RJ, Kovalchuk O. Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle (Georgetown, Tex.). 7: 1238-45. PMID 18418050  0.36
2008 Koturbash I, Loree J, Kutanzi K, Koganow C, Pogribny I, Kovalchuk O. In vivo bystander effect: cranial X-irradiation leads to elevated DNA damage, altered cellular proliferation and apoptosis, and increased p53 levels in shielded spleen. International Journal of Radiation Oncology, Biology, Physics. 70: 554-62. PMID 18207032 DOI: 10.1016/j.ijrobp.2007.09.039  0.68
2008 Kovalchuk O. Epigenetic research sheds new light on the nature of interactions between organisms and their environment. Environmental and Molecular Mutagenesis. 49: 1-3. PMID 18196589 DOI: 10.1002/em.20362  1
2008 Kovalchuk O, Baulch JE. Epigenetic changes and nontargeted radiation effects--is there a link? Environmental and Molecular Mutagenesis. 49: 16-25. PMID 18172877 DOI: 10.1002/em.20361  0.48
2008 Yauk CL, Polyzos A, Rowan-Carroll A, Kortubash I, Williams A, Kovalchuk O. Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of action. Environmental and Molecular Mutagenesis. 49: 26-35. PMID 18172875 DOI: 10.1002/em.20359  0.32
2008 Boyko A, Kovalchuk I. Epigenetic control of plant stress response. Environmental and Molecular Mutagenesis. 49: 61-72. PMID 17948278 DOI: 10.1002/em.20347  0.44
2007 Kovalchuk O, Tryndyak VP, Montgomery B, Boyko A, Kutanzi K, Zemp F, Warbritton AR, Latendresse JR, Kovalchuk I, Beland FA, Pogribny IP. Estrogen-induced rat breast carcinogenesis is characterized by alterations in DNA methylation, histone modifications and aberrant microRNA expression. Cell Cycle (Georgetown, Tex.). 6: 2010-8. PMID 17700064 DOI: 10.4161/cc.6.16.4549  0.96
2007 Kovalchuk I, Molinier J, Yao Y, Arkhipov A, Kovalchuk O. Transcriptome analysis reveals fundamental differences in plant response to acute and chronic exposure to ionizing radiation. Mutation Research. 624: 101-13. PMID 17568626 DOI: 10.1016/j.mrfmmm.2007.04.009  0.84
2007 Chekhun VF, Lukyanova NY, Kovalchuk O, Tryndyak VP, Pogribny IP. Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets. Molecular Cancer Therapeutics. 6: 1089-98. PMID 17363502 DOI: 10.1158/1535-7163.MCT-06-0663  0.44
2007 Koturbash I, Boyko A, Rodriguez-Juarez R, McDonald RJ, Tryndyak VP, Kovalchuk I, Pogribny IP, Kovalchuk O. Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo. Carcinogenesis. 28: 1831-8. PMID 17347136 DOI: 10.1093/carcin/bgm053  0.96
2007 Pogribny IP, Tryndyak VP, Boyko A, Rodriguez-Juarez R, Beland FA, Kovalchuk O. Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. Mutation Research. 619: 30-7. PMID 17343880 DOI: 10.1016/j.mrfmmm.2006.12.006  0.44
2007 Boyko A, Kathiria P, Zemp FJ, Yao Y, Pogribny I, Kovalchuk I. Transgenerational changes in the genome stability and methylation in pathogen-infected plants: (virus-induced plant genome instability). Nucleic Acids Research. 35: 1714-25. PMID 17311811 DOI: 10.1093/nar/gkm029  0.92
2006 Loree J, Koturbash I, Kutanzi K, Baker M, Pogribny I, Kovalchuk O. Radiation-induced molecular changes in rat mammary tissue: Possible implications for radiation-induced carcinogenesis International Journal of Radiation Biology. 82: 805-815. PMID 17148264 DOI: 10.1080/09553000600960027  0.4
2006 Boyko A, Greer M, Kovalchuk I. Acute exposure to UVB has a more profound effect on plant genome stability than chronic exposure. Mutation Research. 602: 100-9. PMID 17027865 DOI: 10.1016/j.mrfmmm.2006.08.008  0.44
2006 Koturbash I, Baker M, Loree J, Kutanzi K, Hudson D, Pogribny I, Sedelnikova O, Bonner W, Kovalchuk O. Epigenetic dysregulation underlies radiation-induced transgenerational genome instability in vivo International Journal of Radiation Oncology Biology Physics. 66: 327-330. PMID 16965987 DOI: 10.1016/j.ijrobp.2006.06.012  0.48
2006 Tryndyak V, Kovalchuk O, Pogribny IP. Identification of differentially methylated sites within unmethylated DNA domains in normal and cancer cells. Analytical Biochemistry. 356: 202-7. PMID 16824473 DOI: 10.1016/j.ab.2006.05.019  0.36
2006 Boyko A, Hudson D, Bhomkar P, Kathiria P, Kovalchuk I. Increase of homologous recombination frequency in vascular tissue of Arabidopsis plants exposed to salt stress. Plant & Cell Physiology. 47: 736-42. PMID 16608867 DOI: 10.1093/pcp/pcj045  0.68
2006 Boyko A, Zemp F, Filkowski J, Kovalchuk I. Double-strand break repair in plants is developmentally regulated. Plant Physiology. 141: 488-97. PMID 16474027 DOI: 10.1104/pp.105.074658  0.6
2006 Boyko A, Filkowski J, Hudson D, Kovalchuk I. Homologous recombination in plants is organ specific. Mutation Research. 595: 145-55. PMID 16442571 DOI: 10.1016/j.mrfmmm.2005.11.009  0.6
2006 Tryndyak VP, Kovalchuk O, Pogribny IP. Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biology & Therapy. 5: 65-70. PMID 16322686  0.44
2006 Cassie S, Koturbash I, Hudson D, Baker M, Ilnytskyy Y, Rodriguez-Juarez R, Weber E, Kovalchuk O. Novel retinoblastoma binding protein RBBP9 modulates sex-specific radiation responses in vivo Carcinogenesis. 27: 465-474. PMID 16272168 DOI: 10.1093/carcin/bgi261  0.4
2005 Pogribny I, Koturbash I, Tryndyak V, Hudson D, Stevenson SM, Sedelnikova O, Bonner W, Kovalchuk O. Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus. Molecular Cancer Research : McR. 3: 553-61. PMID 16254189 DOI: 10.1158/1541-7786.MCR-05-0074  0.36
2005 Koturbash I, Pogribny I, Kovalchuk O. Stable loss of global DNA methylation in the radiation-target tissue--a possible mechanism contributing to radiation carcinogenesis? Biochemical and Biophysical Research Communications. 337: 526-33. PMID 16202973 DOI: 10.1016/j.bbrc.2005.09.084  0.56
2005 Besplug J, Burke P, Ponton A, Filkowski J, Titov V, Kovalchuk I, Kovalchuk O. Sex and tissue-specific differences in low-dose radiation-induced oncogenic signaling. International Journal of Radiation Biology. 81: 157-68. PMID 16019925 DOI: 10.1080/09553000500103512  0.96
2005 Boyko A, Filkowski J, Kovalchuk I. Homologous recombination in plants is temperature and day-length dependent. Mutation Research. 572: 73-83. PMID 15790491 DOI: 10.1016/j.mrfmmm.2004.12.011  0.6
2005 Molinier J, Oakeley EJ, Niederhauser O, Kovalchuk I, Hohn B. Dynamic response of plant genome to ultraviolet radiation and other genotoxic stresses. Mutation Research. 571: 235-47. PMID 15748650 DOI: 10.1016/j.mrfmmm.2004.09.016  0.84
2005 Kovalchuk I, Titov V, Hohn B, Kovalchuk O. Transcriptome profiling reveals similarities and differences in plant responses to cadmium and lead. Mutation Research. 570: 149-61. PMID 15708574 DOI: 10.1016/j.mrfmmm.2004.10.004  0.96
2005 Ilnytskyy Y, Yao Y, Kovalchuk I. Double-strand break repair machinery is sensitive to UV radiation. Journal of Molecular Biology. 345: 707-15. PMID 15588820 DOI: 10.1016/j.jmb.2004.11.001  0.92
2004 Dube T, Kovalchuk I, Hohn B, Thomson JA. Agrobacterium tumefaciens-mediated transformation of plants by the pTF-FC2 plasmid is efficient and strictly dependent on the MobA protein. Plant Molecular Biology. 55: 531-9. PMID 15604698 DOI: 10.1007/s11103-004-1159-1  0.32
2004 Raiche J, Rodriguez-Juarez R, Pogribny I, Kovalchuk O. Sex- and tissue-specific expression of maintenance and de novo DNA methyltransferases upon low dose X-irradiation in mice. Biochemical and Biophysical Research Communications. 325: 39-47. PMID 15522198 DOI: 10.1016/j.bbrc.2004.10.002  0.84
2004 Pogribny I, Raiche J, Slovack M, Kovalchuk O. Dose-dependence, sex- and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes. Biochemical and Biophysical Research Communications. 320: 1253-61. PMID 15249225 DOI: 10.1016/j.bbrc.2004.06.081  0.76
2004 Besplug J, Filkowski J, Burke P, Kovalchuk I, Kovalchuk O. Atrazine induces homologous recombination but not point mutation in the transgenic plant-based biomonitoring assay. Archives of Environmental Contamination and Toxicology. 46: 296-300. PMID 15195800  0.96
2004 Kovalchuk I, Pelczar P, Kovalchuk O. High frequency of nucleotide misincorporations upon the processing of double-strand breaks. Dna Repair. 3: 217-23. PMID 15177037 DOI: 10.1016/j.dnarep.2003.09.011  0.96
2004 Kovalchuk O, Ponton A, Filkowski J, Kovalchuk I. Dissimilar genome response to acute and chronic low-dose radiation in male and female mice. Mutation Research. 550: 59-72. PMID 15135641 DOI: 10.1016/j.mrfmmm.2004.02.007  0.96
2004 Kovalchuk I, Abramov V, Pogribny I, Kovalchuk O. Molecular aspects of plant adaptation to life in the Chernobyl zone. Plant Physiology. 135: 357-63. PMID 15133154 DOI: 10.1104/pp.104.040477  0.96
2004 Ilnytskyy Y, Boyko A, Kovalchuk I. Luciferase-based transgenic recombination assay is more sensitive than beta-glucoronidase-based. Mutation Research. 559: 189-97. PMID 15066586 DOI: 10.1016/j.mrgentox.2004.02.001  0.88
2004 Kovalchuk O, Burke P, Besplug J, Slovack M, Filkowski J, Pogribny I. Methylation changes in muscle and liver tissues of male and female mice exposed to acute and chronic low-dose X-ray-irradiation. Mutation Research. 548: 75-84. PMID 15063138 DOI: 10.1016/j.mrfmmm.2003.12.016  0.52
2004 Filkowski J, Kovalchuk O, Kovalchuk I. Genome stability of vtc1, tt4, and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. The Plant Journal : For Cell and Molecular Biology. 38: 60-9. PMID 15053760 DOI: 10.1111/j.1365-313X.2004.02020.x  0.96
2004 Filkowski J, Yeoman A, Kovalchuk O, Kovalchuk I. Systemic plant signal triggers genome instability. The Plant Journal : For Cell and Molecular Biology. 38: 1-11. PMID 15053755 DOI: 10.1111/j.1365-313X.2004.02025.x  0.96
2003 Kovalchuk I, Kovalchuk O. A new use for transgenic plants--environmental biomonitors. Biotechnology & Genetic Engineering Reviews. 20: 23-45. PMID 14997845  0.96
2003 Filkowski J, Besplug J, Burke P, Kovalchuk I, Kovalchuk O. Genotoxicity of 2,4-D and dicamba revealed by transgenic Arabidopsis thaliana plants harboring recombination and point mutation markers. Mutation Research. 542: 23-32. PMID 14644350  0.96
2003 Kovalchuk O, Burke P, Arkhipov A, Kuchma N, James SJ, Kovalchuk I, Pogribny I. Genome hypermethylation in Pinus silvestris of Chernobyl--a mechanism for radiation adaptation? Mutation Research. 529: 13-20. PMID 12943916  0.96
2003 Pelczar P, Kalck V, Kovalchuk I. Different genome maintenance strategies in human and tobacco cells. Journal of Molecular Biology. 331: 771-9. PMID 12909009  0.32
2003 Kovalchuk I, Kovalchuk O, Kalck V, Boyko V, Filkowski J, Heinlein M, Hohn B. Pathogen-induced systemic plant signal triggers DNA rearrangements. Nature. 423: 760-2. PMID 12802336 DOI: 10.1038/nature01683  0.96
2003 Kovalchuk O, Kovalchuk I, Arkhipov A, Hohn B, Dubrova YE. Extremely complex pattern of microsatellite mutation in the germline of wheat exposed to the post-Chernobyl radioactive contamination. Mutation Research. 525: 93-101. PMID 12650909 DOI: 10.1016/S0027-5107(03)00006-X  0.96
2001 Kovalchuk O, Titov V, Hohn B, Kovalchuk I. A sensitive transgenic plant system to detect toxic inorganic compounds in the environment. Nature Biotechnology. 19: 568-72. PMID 11385463 DOI: 10.1038/89327  0.32
2000 Kovalchuk O, Dubrova YE, Arkhipov A, Hohn B, Kovalchuk I. Wheat mutation rate after Chernobyl. Nature. 407: 583-4. PMID 11034198 DOI: 10.1038/35036692  0.4
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