Charles D. Loftin - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Pharmacology, Pharmacy, Molecular Biology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Oestreich JH, Steinhubl SR, Ferraris SP, Loftin CD, Akers WS. Effect of genetic variation in P2Y12 on TRAP-stimulated platelet response in healthy subjects. Journal of Thrombosis and Thrombolysis. 38: 372-9. PMID 24510678 DOI: 10.1007/S11239-014-1058-5  0.32
2013 Trivedi DB, Loftin CD, Clark J, Myers P, DeGraff LM, Cheng J, Zeldin DC, Langenbach R. β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice. Circulation Research. 112: 1219-29. PMID 23524589 DOI: 10.1161/Circresaha.112.280399  0.32
2012 Ghoshal S, Loftin CD. Cyclooxygenase-2 inhibition attenuates abdominal aortic aneurysm progression in hyperlipidemic mice. Plos One. 7: e44369. PMID 23209546 DOI: 10.1371/Journal.Pone.0044369  0.32
2012 Mukherjee K, Gitlin JM, Loftin CD. Effectiveness of cyclooxygenase-2 inhibition in limiting abdominal aortic aneurysm progression in mice correlates with a differentiated smooth muscle cell phenotype. Journal of Cardiovascular Pharmacology. 60: 520-9. PMID 22967986 DOI: 10.1097/Fjc.0B013E318270B968  0.32
2011 Banks SL, Paudel KS, Brogden NK, Loftin CD, Stinchcomb AL. Diclofenac enables prolonged delivery of naltrexone through microneedle-treated skin. Pharmaceutical Research. 28: 1211-9. PMID 21301935 DOI: 10.1007/S11095-011-0372-2  0.32
2011 Ghoshal S, Trivedi DB, Graf GA, Loftin CD. Cyclooxygenase-2 deficiency attenuates adipose tissue differentiation and inflammation in mice. The Journal of Biological Chemistry. 286: 889-98. PMID 20961858 DOI: 10.1074/Jbc.M110.139139  0.32
2010 Long S, Theiss KL, Mattei A, Loftin CD, Li T. Solid-state properties of the cyclooxygenase-1-selective inhibitor, SC-560. Aaps Pharmscitech. 11: 485-8. PMID 20306238 DOI: 10.1208/S12249-010-9407-Y  0.32
2009 Long S, Theiss KL, Li T, Loftin CD. Cyclo-oxygenase-1-selective inhibitor SC-560. Acta Crystallographica. Section E, Structure Reports Online. 65: o360. PMID 21581958 DOI: 10.1107/S1600536809001779  0.32
2009 Kelso ML, Scheff SW, Pauly JR, Loftin CD. Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. Bmc Neuroscience. 10: 108. PMID 19719848 DOI: 10.1186/1471-2202-10-108  0.32
2009 Gitlin JM, Loftin CD. Cyclooxygenase-2 inhibition increases lipopolysaccharide-induced atherosclerosis in mice. Cardiovascular Research. 81: 400-7. PMID 18948273 DOI: 10.1093/Cvr/Cvn286  0.32
2007 Gitlin JM, Trivedi DB, Langenbach R, Loftin CD. Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice. Cardiovascular Research. 73: 227-36. PMID 17137566 DOI: 10.1016/J.Cardiores.2006.10.015  0.32
2006 Trivedi DB, Sugimoto Y, Loftin CD. Attenuated cyclooxygenase-2 expression contributes to patent ductus arteriosus in preterm mice. Pediatric Research. 60: 669-74. PMID 17065565 DOI: 10.1203/01.Pdr.0000246480.13170.C0  0.32
2006 King VL, Trivedi DB, Gitlin JM, Loftin CD. Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1137-43. PMID 16514081 DOI: 10.1161/01.Atv.0000216119.79008.Ac  0.32
2004 Schneider A, Guan Y, Zhang Y, Magnuson MA, Pettepher C, Loftin CD, Langenbach R, Breyer RM, Breyer MD. Generation of a conditional allele of the mouse prostaglandin EP4 receptor. Genesis (New York, N.Y. : 2000). 40: 7-14. PMID 15354288 DOI: 10.1002/Gene.20048  0.32
2004 Gray T, Nettesheim P, Loftin C, Koo JS, Bonner J, Peddada S, Langenbach R. Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling. Molecular Pharmacology. 66: 337-46. PMID 15266025 DOI: 10.1124/Mol.66.2.337  0.32
2002 Loftin CD, Tiano HF, Langenbach R. Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2. Prostaglandins & Other Lipid Mediators. 68: 177-85. PMID 12432917 DOI: 10.1016/S0090-6980(02)00028-X  0.32
2002 Loftin CD, Trivedi DB, Langenbach R. Cyclooxygenase-1-selective inhibition prolongs gestation in mice without adverse effects on the ductus arteriosus. The Journal of Clinical Investigation. 110: 549-57. PMID 12189249 DOI: 10.1172/JCI14924  0.32
2002 Tiano HF, Loftin CD, Akunda J, Lee CA, Spalding J, Sessoms A, Dunson DB, Rogan EG, Morham SG, Smart RC, Langenbach R. Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. Cancer Research. 62: 3395-401. PMID 12067981  0.32
2002 Kim KS, Baek SJ, Flake GP, Loftin CD, Calvo BF, Eling TE. Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue. Gastroenterology. 122: 1388-98. PMID 11984525  0.32
2001 Xu H, Izon DJ, Loftin C, Spain LM. The COX-2 inhibitor NS-398 causes T-cell developmental disruptions independent of COX-2 enzyme inhibition. Cellular Immunology. 214: 184-93. PMID 12088417 DOI: 10.1006/cimm.2001.1891  0.32
1999 Langenbach R, Loftin CD, Lee C, Tiano H. Cyclooxygenase-deficient mice. A summary of their characteristics and susceptibilities to inflammation and carcinogenesis. Annals of the New York Academy of Sciences. 889: 52-61. PMID 10668482 DOI: 10.1111/j.1749-6632.1999.tb08723.x  0.32
1999 Langenbach R, Loftin C, Lee C, Tiano H. Cyclooxygenase knockout mice: models for elucidating isoform-specific functions. Biochemical Pharmacology. 58: 1237-46. PMID 10487525 DOI: 10.1016/S0006-2952(99)00158-6  0.32
1996 Loftin CD, Eling TE. Prostaglandin synthase 2 expression in epidermal growth factor-dependent proliferation of mouse keratinocytes. Archives of Biochemistry and Biophysics. 330: 419-29. PMID 8660674 DOI: 10.1006/abbi.1996.0271  0.32
1996 Chulada PC, Loftin CD, Winn VD, Young DA, Tiano HF, Eling TE, Langenbach R. Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid. Archives of Biochemistry and Biophysics. 330: 301-13. PMID 8660660 DOI: 10.1006/Abbi.1996.0257  0.32
1995 Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Lee CA, Goulding EH, Kluckman KD, Kim HS, Smithies O. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell. 83: 483-92. PMID 8521478 DOI: 10.1016/0092-8674(95)90126-4  0.32
1995 Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, Smithies O. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell. 83: 473-82. PMID 8521477 DOI: 10.1016/0092-8674(95)90125-6  0.32
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