Hassan Fahmi - Publications

Affiliations: 
Pharmacology Université de Montréal, Montréal, Canada 
Area:
Molecular Biology

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Najar M, Martel-Pelletier J, Pelletier JP, Fahmi H. Novel insights for improving the therapeutic safety and efficiency of mesenchymal stromal cells. World Journal of Stem Cells. 12: 1474-1491. PMID 33505596 DOI: 10.4252/wjsc.v12.i12.1474  0.48
2020 Ouhaddi Y, Najar M, Paré F, Lussier B, Urade Y, Benderdour M, Pelletier JP, Martel-Pelletier J, Fahmi H. L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis. Aging. 12. PMID 33361529 DOI: 10.18632/aging.202367  0.48
2020 Najar M, Martel-Pelletier J, Pelletier JP, Fahmi H. Mesenchymal Stromal Cell Immunology for Efficient and Safe Treatment of Osteoarthritis. Frontiers in Cell and Developmental Biology. 8: 567813. PMID 33072752 DOI: 10.3389/Fcell.2020.567813  0.48
2020 Najar M, Ouhaddi Y, Paré F, Lussier B, Urade Y, Kapoor M, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. Role of Lipocalin-type prostaglandin D synthase in experimental osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32336048 DOI: 10.1002/Art.41297  0.48
2020 Paré F, Tardif G, Fahmi H, Ouhaddi Y, Pelletier JP, Martel-Pelletier J. In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice. Aging. 12. PMID 32012117 DOI: 10.18632/aging.102784  0.48
2019 Najar M, Bouhtit F, Melki R, Afif H, Hamal A, Fahmi H, Merimi M, Lagneaux L. Mesenchymal Stromal Cell-Based Therapy: New Perspectives and Challenges. Journal of Clinical Medicine. 8. PMID 31071990 DOI: 10.3390/Jcm8050626  0.4
2019 Benabdoun HA, Kulbay M, Rondon EP, Vallières F, Shi Q, Fernandes J, Fahmi H, Benderdour M. In vitro and in vivo assessment of the proresolutive and antiresorptive actions of resolvin D1: relevance to arthritis. Arthritis Research & Therapy. 21: 72. PMID 30867044 DOI: 10.1186/S13075-019-1852-8  0.48
2018 Najar M, Ouhaddi Y, Bouhtit F, Melki R, Afif H, Boukhatem N, Merimi M, Fahmi H. Empowering the immune fate of bone marrow mesenchymal stromal cells: gene and protein changes. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 30426152 DOI: 10.1007/S00011-018-1198-8  0.4
2018 Valverde-Franco G, Tardif G, Mineau F, Paré F, Lussier B, Fahmi H, Pelletier JP, Martel-Pelletier J. High in vivo levels of adipsin lead to increased knee tissue degradation in osteoarthritis: data from humans and animal models. Rheumatology (Oxford, England). PMID 29982662 DOI: 10.1093/Rheumatology/Key181  0.48
2018 Farrán A, Valverde-Franco G, Tío L, Lussier B, Fahmi H, Pelletier JP, Bishop PN, Monfort J, Martel-Pelletier J. In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis. Scientific Reports. 8: 457. PMID 29323130 DOI: 10.1038/S41598-017-18047-W  0.48
2017 Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, ... ... Fahmi H, et al. Corrigendum: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis. Nature Medicine. 23: 1499. PMID 29216045 DOI: 10.1038/Nm1217-1499B  0.48
2017 Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, ... ... Fahmi H, et al. ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis. Nature Medicine. PMID 29058717 DOI: 10.1038/Nm.4419  0.48
2017 Habouri L, El Mansouri FE, Ouhaddi Y, Lussier B, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. Accelerated development of aging-associated and instability-induced osteoarthritis in 12/15-lipoxygenase deficient mice. Osteoarthritis and Cartilage. PMID 28694081 DOI: 10.1016/J.Joca.2017.07.001  0.48
2017 Ouhaddi Y, Nebbaki SS, Habouri L, Afif H, Lussier B, Kapoor M, Narumiya S, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. Deletion of the prostaglandin D2 receptor DP1 exacerbates aging-associated and instability-induced osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28544596 DOI: 10.1002/Art.40160  0.48
2017 Abusarah J, Bentz M, Benabdoune H, Rondon PE, Shi Q, Fernandes JC, Fahmi H, Benderdour M. An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 28447122 DOI: 10.1007/S00011-017-1044-4  0.48
2017 Habouri L, Mansouri FE, Ouhaddi Y, Pelletier J, Martel-Pelletier J, Benderdour M, Fahmi H. FRI0009 Accelerated development of aging-associated and instability-induced osteoarthritis in 12/15-lipoxygenase deficient mice Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2017-Eular.6184  0.48
2017 Ouhaddi Y, Habouri L, Pelletier J, Martel-Pelletier J, Benderdour M, Fahmi H. OP0181 Deletion of the prostaglandin D2 receptor DP1 exacerbates aging-associated and instability-induced osteoarthritis Annals of the Rheumatic Diseases. 76: 126-127. DOI: 10.1136/Annrheumdis-2017-Eular.6132  0.48
2017 Benabdoune H, Rondon P, Shi Q, Fernandes J, Fahmi H, Benderdour M. THU0061 Regulation of osteoclast recruitment and activation by resolvin d1 Annals of the Rheumatic Diseases. 76: 221-222. DOI: 10.1136/Annrheumdis-2017-Eular.2934  0.48
2016 Abusarah J, Benabdoun HA, Shi Q, Lussier B, Martel-Pelletier J, Malo M, Fernandes JC, Pereira de Souza F, Fahmi H, Benderdour M. Elucidating the Role of Protandim and 6-Gingerol in Protection Against Osteoarthritis. Journal of Cellular Biochemistry. PMID 27463229 DOI: 10.1002/Jcb.25659  0.48
2016 Li YH, Tardif G, Hum D, Kapoor M, Fahmi H, Pelletier JP, Martel-Pelletier J. The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target. Arthritis Research & Therapy. 18: 172. PMID 27435272 DOI: 10.1186/S13075-016-1070-6  0.48
2016 Benabdoune H, Rondon EP, Shi Q, Fernandes J, Ranger P, Fahmi H, Benderdour M. The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 27056390 DOI: 10.1007/S00011-016-0946-X  0.48
2015 Valverde-Franco G, Lussier B, Hum D, Wu J, Hamadjida A, Dancause N, Fahmi H, Kapoor M, Pelletier JP, Martel-Pelletier J. Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo. Arthritis Research & Therapy. 18: 65. PMID 26980243 DOI: 10.1186/S13075-016-0965-6  0.48
2015 Oliveira BS, Zunzunegui MV, Quinlan J, Fahmi H, Tu MT, Guerra RO. Systematic review of the association between chronic social stress and telomere length: A life course perspective. Ageing Research Reviews. 26: 37-52. PMID 26732034 DOI: 10.1016/J.Arr.2015.12.006  0.48
2015 Benderdour M, Martel-Pelletier J, Pelletier JP, Kapoor M, Zunzunegui MV, Fahmi H. Cellular Aging, Senescence and Autophagy Processes in Osteoarthritis. Current Aging Science. 8: 147-57. PMID 26212056 DOI: 10.2174/1874609808666150727111530  0.48
2015 Vasheghani F, Zhang Y, Li YH, Blati M, Fahmi H, Lussier B, Roughley P, Lagares D, Endisha H, Saffar B, Lajeunesse D, Marshall WK, Rampersaud YR, Mahomed NN, Gandhi R, et al. PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage. Annals of the Rheumatic Diseases. 74: 569-78. PMID 25573665 DOI: 10.1136/Annrheumdis-2014-205743  0.48
2015 Valverde-Franco G, Hum D, Matsuo K, Lussier B, Pelletier JP, Fahmi H, Kapoor M, Martel-Pelletier J. The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice. The American Journal of Pathology. 185: 335-46. PMID 25453723 DOI: 10.1016/J.Ajpath.2014.10.004  0.48
2015 Zhang Y, Vasheghani F, Li YH, Blati M, Simeone K, Fahmi H, Lussier B, Roughley P, Lagares D, Pelletier JP, Martel-Pelletier J, Kapoor M. Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis. Annals of the Rheumatic Diseases. 74: 1432-40. PMID 24651621 DOI: 10.1016/J.Joca.2014.02.631  0.48
2014 Quinlan J, Tu MT, Langlois EV, Kapoor M, Ziegler D, Fahmi H, Zunzunegui MV. Protocol for a systematic review of the association between chronic stress during the life course and telomere length. Systematic Reviews. 3: 40. PMID 24886862 DOI: 10.1186/2046-4053-3-40  0.48
2014 El Mansouri FE, Nebbaki SS, Kapoor M, Afif H, Martel-Pelletier J, Pelletier JP, Benderdour M, Fahmi H. Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes. Arthritis Research & Therapy. 16: R113. PMID 24886859 DOI: 10.1186/Ar4564  0.48
2014 Mongkhon JM, Thach M, Shi Q, Fernandes JC, Fahmi H, Benderdour M. Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 63: 691-701. PMID 24858301 DOI: 10.1016/J.Joca.2014.02.272  0.48
2014 Shi Q, Abusarah J, Zaouter C, Moldovan F, Fernandes JC, Fahmi H, Benderdour M. New evidence implicating 4-hydroxynonenal in the pathogenesis of osteoarthritis in vivo. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2461-71. PMID 24838404 DOI: 10.1002/Art.38704  0.48
2014 Mansouri FEE, Nebbaki S, Kapoor M, Afif H, Martel-Pelletier J, Pelletier J-, Benderdour M, Fahmi H. THU0464 Lsd1-Mediated Demethylation of Histone H3 Lysine 9 Contributes to Interleukin 1-Induced Microsomal Prostaglandin E Synthase-1 Expression Annals of the Rheumatic Diseases. 73: 344-344. DOI: 10.1136/Annrheumdis-2014-Eular.1199  0.48
2013 Tardif G, Pelletier JP, Fahmi H, Hum D, Zhang Y, Kapoor M, Martel-Pelletier J. NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis. Arthritis Research & Therapy. 15: R197. PMID 24257415 DOI: 10.1186/Ar4387  0.48
2013 Shi Q, Abusarah J, Baroudi G, Fernandes JC, Fahmi H, Benderdour M. Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' - authors' reply. Arthritis Research & Therapy. 15: 406. PMID 23566352 DOI: 10.1186/Ar4196  0.48
2013 Nebbaki SS, El Mansouri FE, Afif H, Kapoor M, Benderdour M, Pelletier JP, Martel-Pelletier J, Fahmi H. Expression of peroxisome proliferator-activated receptors α, β, γ, and H- and L-prostaglandin D synthase during osteoarthritis in the spontaneous hartley guinea pig and experimental dog models. The Journal of Rheumatology. 40: 877-90. PMID 23547214 DOI: 10.3899/Jrheum.120738  0.48
2013 Vasheghani F, Monemdjou R, Fahmi H, Zhang Y, Perez G, Blati M, St-Arnaud R, Pelletier JP, Beier F, Martel-Pelletier J, Kapoor M. Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype. The American Journal of Pathology. 182: 1099-106. PMID 23375622 DOI: 10.1016/J.Ajpath.2012.12.012  0.48
2013 Pelletier JP, Kapoor M, Fahmi H, Lajeunesse D, Blesius A, Maillet J, Martel-Pelletier J. Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium. Annals of the Rheumatic Diseases. 72: 250-7. PMID 23065732 DOI: 10.1136/Annrheumdis-2012-201710  0.48
2012 Shi Q, Abusarah J, Baroudi G, Fernandes JC, Fahmi H, Benderdour M. Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis. Arthritis Research & Therapy. 14: R223. PMID 23079082 DOI: 10.1186/Ar4062  0.48
2012 Valverde-Franco G, Pelletier JP, Fahmi H, Hum D, Matsuo K, Lussier B, Kapoor M, Martel-Pelletier J. In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis. Arthritis and Rheumatism. 64: 3614-25. PMID 22833446 DOI: 10.1002/Art.34638  0.48
2012 Bentz M, Zaouter C, Shi Q, Fahmi H, Moldovan F, Fernandes JC, Benderdour M. Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes. Journal of Cellular Biochemistry. 113: 2256-67. PMID 22573548 DOI: 10.1002/Jcb.24096  0.48
2012 Nebbaki SS, El Mansouri FE, Afif H, Kapoor M, Benderdour M, Duval N, Pelletier JP, Martel-Pelletier J, Fahmi H. Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes. Arthritis Research & Therapy. 14: R69. PMID 22455954 DOI: 10.1186/Ar3788  0.48
2012 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M. Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis and Rheumatism. 64: 1551-61. PMID 22131019 DOI: 10.1002/Art.33490  0.48
2012 Kapoor M, Mineau F, Fahmi H, Pelletier JP, Martel-Pelletier J. Glucosamine sulfate reduces prostaglandin E(2) production in osteoarthritic chondrocytes through inhibition of microsomal PGE synthase-1. The Journal of Rheumatology. 39: 635-44. PMID 22089456 DOI: 10.3899/Jrheum.110621  0.48
2011 Benderdour M, Fahmi H, Beaudet F, Fernandes JC, Shi Q. Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts. Journal of Cellular Biochemistry. 112: 2160-9. PMID 21480365 DOI: 10.1002/Jcb.23141  0.48
2011 McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M. mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis. Arthritis Research & Therapy. 13: R6. PMID 21266028 DOI: 10.1186/Ar3226  0.48
2011 Zayed N, El Mansouri FE, Chabane N, Kapoor M, Martel-Pelletier J, Benderdour M, Pelletier JP, Duval N, Fahmi H. Valproic acid suppresses interleukin-1ß-induced microsomal prostaglandin E2 synthase-1 expression in chondrocytes through upregulation of NAB1. The Journal of Rheumatology. 38: 492-502. PMID 21239760 DOI: 10.3899/Jrheum.100907  0.48
2011 Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nature Reviews. Rheumatology. 7: 33-42. PMID 21119608 DOI: 10.1038/Nrrheum.2010.196  0.48
2011 Vaillancourt F, Silva P, Shi Q, Fahmi H, Fernandes JC, Benderdour M. Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis. Journal of Cellular Biochemistry. 112: 107-17. PMID 20872780 DOI: 10.1002/Jcb.22884  0.48
2011 El Mansouri FE, Chabane N, Zayed N, Kapoor M, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes. Arthritis and Rheumatism. 63: 168-79. PMID 20862685 DOI: 10.1002/Art.27762  0.48
2011 Fahmi H, Martel-Pelletier J, Pelletier JP, Kapoor M. Peroxisome proliferator-activated receptor gamma in osteoarthritis. Modern Rheumatology / the Japan Rheumatism Association. 21: 1-9. PMID 20820843 DOI: 10.1007/S10165-010-0347-X  0.48
2011 McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M. Correction: MPGES-1 null mice are resistant to bleomycin-induced skin fibrosis Arthritis Research and Therapy. 13. DOI: 10.1186/Ar3285  0.48
2010 El-Bikai R, Welman M, Margaron Y, Côté JF, Macqueen L, Buschmann MD, Fahmi H, Shi Q, Maghni K, Fernandes JC, Benderdour M. Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis. Arthritis Research & Therapy. 12: R201. PMID 20977750 DOI: 10.1186/Ar3173  0.48
2010 Chen SH, Fahmi H, Shi Q, Benderdour M. Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes. Arthritis Research & Therapy. 12: R21. PMID 20144213 DOI: 10.1186/Ar2926  0.48
2010 Monemdjou R, Fahmi H, Kapoor M. Synovium in the pathophysiology of osteoarthritis Therapy. 7: 661-668. DOI: 10.2217/Thy.10.72  0.48
2009 Zhang J, Wang X, Fahmi H, Wojcik S, Fikes J, Yu Y, Wu J, Luo H. Role of TL1A in the pathogenesis of rheumatoid arthritis. Journal of Immunology (Baltimore, Md. : 1950). 183: 5350-7. PMID 19786547 DOI: 10.4049/jimmunol.0802645  0.48
2009 Chabane N, Zayed N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis. Arthritis Research & Therapy. 11: R44. PMID 19296842 DOI: 10.1186/Ar2652  0.48
2009 Chabane N, Li X, Fahmi H. HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity. Journal of Cellular Biochemistry. 106: 453-63. PMID 19115247 DOI: 10.1002/Jcb.22027  0.48
2009 Chabane N, Zayed N, Benderdour M, Martel-Pelletier J, Pelletier J-, Duval N, Fahmi H. 248 Human Articular Chondrocytes Express 15-Lipoxygenase-1 And -2: Potential Role In Osteoarthritis Osteoarthritis and Cartilage. 17. DOI: 10.1016/S1063-4584(09)60270-3  0.48
2009 Tat SK, Pelletier JP, Lajeunesse D, Fahmi H, Duval N, Martel-Pelletier J. Corrigendum to "Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors" [Bone 43 (2008) 284-291] (DOI:10.1016/j.bone.2008.04.006) Bone. 44: 387. DOI: 10.1016/J.Bone.2008.10.043  0.48
2008 Zayed N, Li X, Chabane N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage. Arthritis Research & Therapy. 10: R146. PMID 19094210 DOI: 10.1186/Ar2581  0.48
2008 Zayed N, Afif H, Chabane N, Mfuna-Endam L, Benderdour M, Martel-Pelletier J, Pelletier JP, Motiani RK, Trebak M, Duval N, Fahmi H. Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. Arthritis and Rheumatism. 58: 3530-40. PMID 18975308 DOI: 10.1002/Art.23958  0.48
2008 Vaillancourt F, Fahmi H, Shi Q, Lavigne P, Ranger P, Fernandes JC, Benderdour M. 4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase. Arthritis Research & Therapy. 10: R107. PMID 18782442 DOI: 10.1186/Ar2503  0.48
2008 Tat SK, Pelletier JP, Lajeunesse D, Fahmi H, Duval N, Martel-Pelletier J. Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors. Bone. 43: 284-91. PMID 18539107 DOI: 10.1016/J.Bone.2008.04.006  0.48
2008 Chabane N, Zayed N, Afif H, Mfuna-Endam L, Benderdour M, Boileau C, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 16: 1267-74. PMID 18417374 DOI: 10.1016/J.Joca.2008.03.009  0.48
2007 Boileau C, Amiable N, Martel-Pelletier J, Fahmi H, Duval N, Pelletier JP. Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study. Arthritis Research & Therapy. 9: R121. PMID 18031579 DOI: 10.1186/Ar2329  0.48
2007 Tat SK, Pelletier JP, Vergés J, Lajeunesse D, Montell E, Fahmi H, Lavigne M, Martel-Pelletier J. Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study. Arthritis Research & Therapy. 9: R117. PMID 17996099 DOI: 10.1186/Ar2325  0.48
2007 Boileau C, Martel-Pelletier J, Fahmi H, Mineau F, Boily M, Pelletier JP. The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways. Arthritis and Rheumatism. 56: 2288-98. PMID 17599749 DOI: 10.1002/Art.22726  0.48
2007 Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes. Arthritis Research & Therapy. 9: R31. PMID 17386086 DOI: 10.1186/Ar2151  0.48
2007 Vaillancourt F, Morquette B, Shi Q, Fahmi H, Lavigne P, Di Battista JA, Fernandes JC, Benderdour M. Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade. Journal of Cellular Biochemistry. 100: 1217-31. PMID 17031850 DOI: 10.1002/Jcb.21110  0.48
2006 Shi Q, Vaillancourt F, Côté V, Fahmi H, Lavigne P, Afif H, Di Battista JA, Fernandes JC, Benderdour M. Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal. Arthritis Research & Therapy. 8: R159. PMID 17042956 DOI: 10.1186/Ar2066  0.48
2006 Cheng S, Afif H, Martel-Pelletier J, Benderdour M, Pelletier JP, Hilal G, Haraoui P, Raynauld JP, Choquette D, Fahmi H. Association of polymorphisms in the peroxisome proliferator-activated receptor gamma gene and osteoarthritis of the knee. Annals of the Rheumatic Diseases. 65: 1394-7. PMID 16973789 DOI: 10.1136/ard.2006.051904  0.48
2006 Martel-Pelletier J, Lajeunesse D, Fahmi H, Tardif G, Pelletier JP. New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets. Current Rheumatology Reports. 8: 30-6. PMID 16515762 DOI: 10.1007/S11926-006-0022-6  0.48
2005 Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H. Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. The Journal of Rheumatology. 32: 887-95. PMID 15868626 DOI: 10.1186/Ar1439  0.48
2005 Farrajota K, Cheng S, Martel-Pelletier J, Afif H, Pelletier JP, Li X, Ranger P, Fahmi H. Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism. Arthritis and Rheumatism. 52: 94-104. PMID 15641079 DOI: 10.1002/Art.20714  0.48
2005 Boileau C, Pelletier JP, Tardif G, Fahmi H, Laufer S, Lavigne M, Martel-Pelletier J. The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway. Annals of the Rheumatic Diseases. 64: 891-8. PMID 15498796 DOI: 10.1136/Ard.2004.026906  0.48
2004 Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP. Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids. Arthritis and Rheumatism. 50: 3925-33. PMID 15593193 DOI: 10.1002/Art.20632  0.48
2004 Fahmi H. mPGES-1 as a novel target for arthritis. Current Opinion in Rheumatology. 16: 623-7. PMID 15314505 DOI: 10.1097/01.Bor.0000129664.81052.8E  0.48
2004 Cheng S, Afif H, Martel-Pelletier J, Pelletier JP, Li X, Farrajota K, Lavigne M, Fahmi H. Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. The Journal of Biological Chemistry. 279: 22057-65. PMID 15023995 DOI: 10.1074/Jbc.M402828200  0.48
2004 Martel-Pelletier J, Pelletier JP, Fahmi H. New insights into prostaglandin biology. The Journal of Rheumatology. 31: 14-6. PMID 14705212  0.48
2003 Martel-Pelletier J, Pelletier JP, Fahmi H. Cyclooxygenase-2 and prostaglandins in articular tissues. Seminars in Arthritis and Rheumatism. 33: 155-67. PMID 14671726 DOI: 10.1016/S0049-0172(03)00134-3  0.48
2002 Fahmi H, Pelletier JP, Mineau F, Martel-Pelletier J. 15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 10: 845-8. PMID 12435328 DOI: 10.1053/Joca.2002.0835  0.48
2002 Fahmi H, Pelletier JP, Di Battista JA, Cheung HS, Fernandes JC, Martel-Pelletier J. Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 10: 100-8. PMID 11869069 DOI: 10.1053/Joca.2001.0485  0.48
2002 Kalajdzic T, Faour WH, He QW, Fahmi H, Martel-Pelletier J, Pelletier JP, Di Battista JA. Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism. Arthritis and Rheumatism. 46: 494-506. PMID 11840453 DOI: 10.1002/Art.10055  0.48
2002 Fahmi H, Pelletier JP, Martel-Pelletier J. PPARgamma ligands as modulators of inflammatory and catabolic responses in arthritis. An overview. The Journal of Rheumatology. 29: 3-14. PMID 11824967  0.48
2001 Fahmi H, He Y, Zhang M, Martel-Pelletier J, Pelletier JP, Di Battista JA. Nimesulide reduces interleukin-1beta-induced cyclooxygenase-2 gene expression in human synovial fibroblasts. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 9: 332-40. PMID 11399097 DOI: 10.1053/Joca.2000.0393  0.48
2001 Fahmi H, Di Battista JA, Pelletier JP, Mineau F, Ranger P, Martel-Pelletier J. Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes. Arthritis and Rheumatism. 44: 595-607. PMID 11263774 DOI: 10.1002/1529-0131(200103)44:3<595::Aid-Anr108>3.0.Co;2-8  0.48
1997 Ancuta P, Fahmi H, Pons JF, Le Blay K, Chaby R. Involvement of the membrane form of tumour necrosis factor-alpha in lipopolysaccharide-induced priming of mouse peritoneal macrophages for enhanced nitric oxide response to lipopolysaccharide. Immunology. 92: 259-66. PMID 9415035 DOI: 10.1046/j.1365-2567.1997.00338.x  0.48
1996 Fahmi H, Ancuta P, Perrier S, Chaby R. Preexposure of mouse peritoneal macrophages to lipopolysaccharide and other stimuli enhances the nitric oxide response to secondary stimuli. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 45: 347-53. PMID 8841836 DOI: 10.1007/BF02252947  0.48
1995 Fahmi H, Charon D, Mondange M, Chaby R. Endotoxin-induced desensitization of mouse macrophages is mediated in part by nitric oxide production. Infection and Immunity. 63: 1863-9. PMID 7729896 DOI: 10.1128/IAI.63.5.1863-1869.1995  0.48
1994 Fahmi H, Chaby R. Differential recovery of macrophages from endotoxin-tolerant states elicited by lipopolysaccharide and enzymatic treatments. Immunological Investigations. 23: 243-58. PMID 7959959 DOI: 10.3109/08820139409066821  0.48
1993 Fahmi H, Chaby R. Selective refractoriness of macrophages to endotoxin-induced production of tumor necrosis factor, elicited by an autocrine mechanism. Journal of Leukocyte Biology. 53: 45-52. PMID 8426091 DOI: 10.1002/jlb.53.1.45  0.48
1993 Fahmi H, Chaby R. Desensitization of macrophages to endotoxin effects is not correlated with a down-regulation of lipopolysaccharide-binding sites. Cellular Immunology. 150: 219-29. PMID 7688269 DOI: 10.1006/cimm.1993.1191  0.48
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