Kostas Pantopoulos - Publications

Affiliations: 
Experimental Medicine McGill University, Montreal, QC, Canada 
Area:
Molecular Biology, Physiology Biology

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Wang J, Pantopoulos K. Regulation of cellular iron metabolism. The Biochemical Journal. 434: 365-81. PMID 21348856 DOI: 10.1042/BJ20101825  0.36
2010 Maffettone C, Chen G, Drozdov I, Ouzounis C, Pantopoulos K. Tumorigenic properties of iron regulatory protein 2 (IRP2) mediated by its specific 73-amino acids insert. Plos One. 5: e10163. PMID 20405006 DOI: 10.1371/journal.pone.0010163  0.36
2010 Schümann K, Herbach N, Kerling C, Seifert M, Fillebeen C, Prysch I, Reich J, Weiss G, Pantopoulos K. Iron absorption and distribution in TNF(DeltaARE/+) mice, a model of chronic inflammation. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 24: 58-66. PMID 20122582 DOI: 10.1016/j.jtemb.2009.10.002  0.44
2008 Wang J, Chen G, Filebeen C, Pantopoulos K. Insights on regulation and function of the iron regulatory protein 1 (IRP1). Hemoglobin. 32: 109-15. PMID 18274988 DOI: 10.1080/03630260701680326  0.36
2008 Wang J, Chen G, Lee J, Pantopoulos K. Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity. Bmc Molecular Biology. 9: 15. PMID 18226225 DOI: 10.1186/1471-2199-9-15  0.36
2007 Andriopoulos B, Hegedüsch S, Mangin J, Riedel HD, Hebling U, Wang J, Pantopoulos K, Mueller S. Sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron-responsive element network. The Journal of Biological Chemistry. 282: 20301-8. PMID 17517884 DOI: 10.1074/jbc.M702463200  0.36
2007 Fillebeen C, Muckenthaler M, Andriopoulos B, Bisaillon M, Mounir Z, Hentze MW, Koromilas AE, Pantopoulos K. Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells. Journal of Hepatology. 47: 12-22. PMID 17399844 DOI: 10.1016/j.jhep.2007.01.035  0.88
2007 Wang J, Fillebeen C, Chen G, Biederbick A, Lill R, Pantopoulos K. Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway. Molecular and Cellular Biology. 27: 2423-30. PMID 17242182 DOI: 10.1128/MCB.01111-06  0.36
2007 Chen G, Fillebeen C, Wang J, Pantopoulos K. Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts. Carcinogenesis. 28: 785-91. PMID 17127713 DOI: 10.1093/carcin/bgl210  0.36
2006 Nie G, Chen G, Sheftel AD, Pantopoulos K, Ponka P. In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin. Blood. 108: 2428-34. PMID 16757684 DOI: 10.1182/blood-2006-04-018341  0.36
2006 Wang J, Fillebeen C, Chen G, Andriopoulos B, Pantopoulos K. Sodium nitroprusside promotes IRP2 degradation via an increase in intracellular iron and in the absence of S nitrosylation at C178. Molecular and Cellular Biology. 26: 1948-54. PMID 16479012 DOI: 10.1128/MCB.26.5.1948-1954.2006  0.36
2005 Wang J, Chen G, Pantopoulos K. Inhibition of transferrin receptor 1 transcription by a cell density response element. The Biochemical Journal. 392: 383-8. PMID 16092918 DOI: 10.1042/BJ20050492  0.36
2005 Wang J, Pantopoulos K. The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL. Biochimica Et Biophysica Acta. 1743: 79-85. PMID 15777842 DOI: 10.1016/j.bbamcr.2004.08.011  0.36
2005 Wang J, Chen G, Pantopoulos K. Nitric oxide inhibits the degradation of IRP2. Molecular and Cellular Biology. 25: 1347-53. PMID 15684386 DOI: 10.1128/MCB.25.4.1347-1353.2005  0.36
2005 Fillebeen C, Rivas-Estilla AM, Bisaillon M, Ponka P, Muckenthaler M, Hentze MW, Koromilas AE, Pantopoulos K. Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus. The Journal of Biological Chemistry. 280: 9049-57. PMID 15637067 DOI: 10.1074/jbc.M412687200  0.88
2004 Schümann K, Brennan K, Weiss M, Pantopoulos K, Hentze MW. Rat duodenal IRP1 activity and iron absorption in iron deficiency and after HO perfusion. European Journal of Clinical Investigation. 34: 275-82. PMID 15086359 DOI: 10.1111/j.1365-2362.2004.01335.x  0.88
2004 Wang J, Chen G, Muckenthaler M, Galy B, Hentze MW, Pantopoulos K. Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity. Molecular and Cellular Biology. 24: 954-65. PMID 14729944  0.88
2003 Mütze S, Hebling U, Stremmel W, Wang J, Arnhold J, Pantopoulos K, Mueller S. Myeloperoxidase-derived hypochlorous acid antagonizes the oxidative stress-mediated activation of iron regulatory protein 1. The Journal of Biological Chemistry. 278: 40542-9. PMID 12888561 DOI: 10.1074/jbc.M307159200  0.36
2003 Wang J, Chen G, Pantopoulos K. The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin. The Biochemical Journal. 370: 891-9. PMID 12464008 DOI: 10.1042/BJ20021607  0.36
2002 Wang J, Buss JL, Chen G, Ponka P, Pantopoulos K. The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells. Febs Letters. 529: 309-12. PMID 12372619  0.36
2002 Wang J, Pantopoulos K. Conditional derepression of ferritin synthesis in cells expressing a constitutive IRP1 mutant. Molecular and Cellular Biology. 22: 4638-51. PMID 12052872  0.36
2002 Mueller S, Pantopoulos K. Activation of iron regulatory protein-1 by oxidative stress. Methods in Enzymology. 348: 324-37. PMID 11885287  0.36
2001 Mueller S, Pantopoulos K, Hübner CA, Stremmel W, Hentze MW. IRP1 activation by extracellular oxidative stress in the perfused rat liver. The Journal of Biological Chemistry. 276: 23192-6. PMID 11297549 DOI: 10.1074/jbc.M100654200  0.88
1999 Brazzolotto X, Gaillard J, Pantopoulos K, Hentze MW, Moulis JM. Human cytoplasmic aconitase (Iron regulatory protein 1) is converted into its [3Fe-4S] form by hydrogen peroxide in vitro but is not activated for iron-responsive element binding. The Journal of Biological Chemistry. 274: 21625-30. PMID 10419470  0.88
1999 Gehring NH, Hentze MW, Pantopoulos K. Inactivation of both RNA binding and aconitase activities of iron regulatory protein-1 by quinone-induced oxidative stress. The Journal of Biological Chemistry. 274: 6219-25. PMID 10037708  0.88
1998 Pantopoulos K, Hentze MW. Activation of iron regulatory protein-1 by oxidative stress in vitro. Proceedings of the National Academy of Sciences of the United States of America. 95: 10559-63. PMID 9724742  0.88
1997 Pantopoulos K, Mueller S, Atzberger A, Ansorge W, Stremmel W, Hentze MW. Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress. The Journal of Biological Chemistry. 272: 9802-8. PMID 9092514  0.88
1996 Pantopoulos K, Weiss G, Hentze MW. Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways. Molecular and Cellular Biology. 16: 3781-8. PMID 8668195  0.88
1996 Gray NK, Pantopoulos K, Dandekar T, Ackrell BA, Hentze MW. Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements. Proceedings of the National Academy of Sciences of the United States of America. 93: 4925-30. PMID 8643505  0.88
1995 Pantopoulos K, Hentze MW. Rapid responses to oxidative stress mediated by iron regulatory protein. The Embo Journal. 14: 2917-24. PMID 7796817  0.88
1995 Pantopoulos K, Gray NK, Hentze MW. Differential regulation of two related RNA-binding proteins, iron regulatory protein (IRP) and IRPB. Rna (New York, N.Y.). 1: 155-63. PMID 7585245  0.88
1995 Pantopoulos K, Hentze MW. Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 92: 1267-71. PMID 7533289  0.88
1994 Pantopoulos K, Weiss G, Hentze MW. Nitric oxide and the post-transcriptional control of cellular iron traffic. Trends in Cell Biology. 4: 82-6. PMID 14731597  0.88
1994 Pantopoulos K, Johansson HE, Hentze MW. The role of the 5' untranslated region of eukaryotic messenger RNAs in translation and its investigation using antisense technologies. Progress in Nucleic Acid Research and Molecular Biology. 48: 181-238. PMID 7938549  0.88
1994 Weiss G, Goossen B, Doppler W, Fuchs D, Pantopoulos K, Werner-Felmayer G, Grünewald K, Wachter H, Hentze MW. Stimulation of IRE-BP activity of IRF by tetrahydrobiopterin and cytokine dependent induction of nitric oxide synthase. Advances in Experimental Medicine and Biology. 356: 133-9. PMID 7534029  0.88
1993 Weiss G, Goossen B, Doppler W, Fuchs D, Pantopoulos K, Werner-Felmayer G, Wachter H, Hentze MW. Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway. The Embo Journal. 12: 3651-7. PMID 7504627  0.88
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