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Dean E. Wilcox - Publications

Affiliations: 
Chemistry Dartmouth College, Hanover, NH, United States 
Area:
Bioinorganic chemistry, thermodynamics of metal-protein interactions, metalloenzymes, nitric oxide biochemistry
Website:
http://www.dartmouth.edu/~chem/faculty/dew.html
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Mehlenbacher MR, Elsiesy R, Lakha R, Villones RLE, Orman M, Vizcarra CL, Meloni G, Wilcox DE, Austin RN. Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu supplants entropically favoured Zn to form Cu clusters under physiological conditions. Chemical Science. 13: 5289-5304. PMID 35655557 DOI: 10.1039/d2sc00676f  0.343
2021 Miller A, Matera-Witkiewicz A, Mikołajczyk A, Wątły J, Wilcox D, Witkowska D, Rowińska-Żyrek M. Zn-Enhanced Asp-Rich Antimicrobial Peptides: N-Terminal Coordination by Zn(II) and Cu(II), Which Distinguishes Cu(II) Binding to Different Peptides. International Journal of Molecular Sciences. 22. PMID 34203496 DOI: 10.3390/ijms22136971  0.304
2019 North ML, Wilcox DE. The Shift from Entropic Cu2+ Binding to Enthalpic Cu+ Binding Determines the Reduction Thermodynamics of Blue Copper Proteins. Journal of the American Chemical Society. PMID 31433629 DOI: 10.1021/Jacs.9B06836  0.424
2017 Pedroso MM, Ely F, Carpenter MC, Mitic N, Gahan LR, Ollis DL, Wilcox DE, Schenk G. Mechanistic Insight from Calorimetric Measurements of the Assembly of the Binuclear Metal Active Site of Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Biochemistry. PMID 28562023 DOI: 10.1021/Acs.Biochem.6B01200  0.785
2016 Wahba HM, Stevenson MJ, Mansour A, Sygusch J, Wilcox DE, Omichinski JG. Structural and biochemical characterization of organotin and organolead compounds binding to the organomercurial lyase MerB provide new insights into its mechanism of carbon-metal bond cleavage. Journal of the American Chemical Society. PMID 27989130 DOI: 10.1021/Jacs.6B11327  0.659
2016 Lisi GP, Hughes RP, Wilcox DE. Coordination contributions to protein stability in metal-substituted carbonic anhydrase. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 27350155 DOI: 10.1007/S00775-016-1375-6  0.713
2016 Wahba H, Lecoq L, Stevenson MJ, Mansour A, Cappadocia L, Lafrance-Vanasse J, Wilkinson KJ, Sygusch J, Wilcox DE, Omichinski JG. Structural and biochemical characterization of a copper-binding mutant of the organomercurial lyase MerB: Insight into the key role of the active site aspartic acid in both Hg-carbon bond cleavage and metal-binding specificity. Biochemistry. PMID 26820485 DOI: 10.1021/Acs.Biochem.5B01298  0.676
2016 Quinn CF, Carpenter MC, Croteau ML, Wilcox DE. Isothermal Titration Calorimetry Measurements of Metal Ions Binding to Proteins. Methods in Enzymology. 567: 3-21. PMID 26794348 DOI: 10.1016/Bs.Mie.2015.08.021  0.792
2016 Carpenter MC, Shami Shah A, DeSilva S, Gleaton A, Su A, Goundie B, Croteau ML, Stevenson MJ, Wilcox DE, Austin RN. Thermodynamics of Pb(ii) and Zn(ii) binding to MT-3, a neurologically important metallothionein. Metallomics : Integrated Biometal Science. PMID 26757944 DOI: 10.1039/C5Mt00209E  0.795
2015 Johnson DK, Stevenson MJ, Almadidy ZA, Jenkins SE, Wilcox DE, Grossoehme NE. Stabilization of Cu(i) for binding and calorimetric measurements in aqueous solution. Dalton Transactions (Cambridge, England : 2003). 44: 16494-505. PMID 26327397 DOI: 10.1039/C5Dt02689J  0.609
2014 Pedroso MM, Ely F, Mitić N, Carpenter MC, Gahan LR, Wilcox DE, Larrabee JL, Ollis DL, Schenk G. Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH). Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 19: 1263-75. PMID 25104333 DOI: 10.1007/S00775-014-1183-9  0.758
2014 Lisi GP, Png CY, Wilcox DE. Thermodynamic contributions to the stability of the insulin hexamer. Biochemistry. 53: 3576-84. PMID 24811232 DOI: 10.1021/Bi401678N  0.694
2014 He X, Swarts SG, Demidenko E, Flood AB, Grinberg O, Gui J, Mariani M, Marsh SD, Ruuge AE, Sidabras JW, Tipikin D, Wilcox DE, Swartz HM. Development and validation of an ex vivo electron paramagnetic resonance fingernail biodosimetric method. Radiation Protection Dosimetry. 159: 172-81. PMID 24803513 DOI: 10.1093/Rpd/Ncu129  0.424
2014 Carpenter MC, Wilcox DE. Thermodynamics of formation of the insulin hexamer: metal-stabilized proton-coupled assembly of quaternary structure. Biochemistry. 53: 1296-301. PMID 24506168 DOI: 10.1021/Bi4016567  0.737
2014 Croteau ML, Su X, Wilcox DE, Aprahamian I. Metal coordination and isomerization of a hydrazone switch Chempluschem. 79: 1214-1224. DOI: 10.1002/Cplu.201402134  0.445
2012 Swartz HM, Flood AB, Williams BB, Dong R, Swarts SG, He X, Grinberg O, Sidabras J, Demidenko E, Gui J, Gladstone DJ, Jarvis LA, Kmiec MM, Kobayashi K, Lesniewski PN, ... ... Wilcox DE, et al. Electron paramagnetic resonance dosimetry for a large-scale radiation incident. Health Physics. 103: 255-67. PMID 22850230 DOI: 10.1097/Hp.0B013E3182588D92  0.418
2012 Rich AM, Bombarda E, Schenk AD, Lee PE, Cox EH, Spuches AM, Hudson LD, Kieffer B, Wilcox DE. Thermodynamics of Zn2+ binding to Cys2His2 and Cys2HisCys zinc fingers and a Cys4 transcription factor site. Journal of the American Chemical Society. 134: 10405-18. PMID 22591173 DOI: 10.1021/Ja211417G  0.764
2012 Cochran JC, Zhao YC, Wilcox DE, Kull FJ. A metal switch for controlling the activity of molecular motor proteins. Nature Structural & Molecular Biology. 19: 122-7. PMID 22198464 DOI: 10.1038/Nsmb.2190  0.354
2011 He X, Gui J, Matthews TP, Williams BB, Swarts SG, Grinberg O, Sidabras J, Wilcox DE, Swartz HM. Advances towards using finger/toenail dosimetry to triage a large population after potential exposure to ionizing radiation. Radiation Measurements. 46: 882-887. PMID 22125410 DOI: 10.1016/J.Radmeas.2011.05.016  0.424
2010 Grossoehme NE, Spuches AM, Wilcox DE. Application of isothermal titration calorimetry in bioinorganic chemistry. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 1183-91. PMID 20725755 DOI: 10.1007/S00775-010-0693-3  0.769
2010 Wilcox DE, He X, Gui J, Ruuge AE, Li H, Williams BB, Swartz HM. Dosimetry based on EPR spectral analysis of fingernail clippings. Health Physics. 98: 309-17. PMID 20065699 DOI: 10.1097/Hp.0B013E3181B27502  0.409
2010 Grossoehme NE, Spuches AM, Wilcox DE. Erratum to: Application of isothermal titration calorimetry in bioinorganic chemistry Jbic Journal of Biological Inorganic Chemistry. 15: 1193-1194. DOI: 10.1007/S00775-010-0707-1  0.679
2009 Wilcox D. Metal Ions in Life Sciences, Volume 5: Metallothionein and Related Chelators Metal Ions in Life Sciences, Volume 5: Metallothionein and Related Chelators . Edited by Astrid Sigel , Helmut Sigel (University of Basel, Switzerland), and Roland K. O. Sigel (University of Zürich, Switzerland). Royal Society of Chemistry: Cambridge. 2009. xxx + 514 pp. $299. ISBN 978-1-84755-899-2 . Journal of the American Chemical Society. 131: 14126-14126. DOI: 10.1021/Ja907058Z  0.34
2008 Spuches AM, Wilcox DE. Monomethylarsenite competes with Zn2+ for binding sites in the glucocorticoid receptor. Journal of the American Chemical Society. 130: 8148-9. PMID 18529053 DOI: 10.1021/Ja802179P  0.757
2008 Wilcox DE. Isothermal titration calorimetry of metal ions binding to proteins: An overview of recent studies Inorganica Chimica Acta. 361: 857-867. DOI: 10.1016/J.Ica.2007.10.032  0.473
2008 Gorodetsky AA, Dietrich LEP, Lee PE, Demple B, Newman DK, Barton JK, Watanabe S, Kita A, Kobayashi K, Miki K, Taylor JL, Moga TG, Karagiaridi O, Wilcox DE, Pletneva EV. Effects of DNA binding on the structural and redox properties of the [2fe-2s] transcription factor soxr Chemtracts. 21: 336-345.  0.64
2007 Grossoehme NE, Mulrooney SB, Hausinger RP, Wilcox DE. Thermodynamics of Ni2+, Cu2+, and Zn2+ binding to the urease metallochaperone UreE. Biochemistry. 46: 10506-16. PMID 17711301 DOI: 10.1021/Bi700171V  0.472
2007 Spuches AM, Argiros HJ, Lee KH, Haas LL, Pero SC, Krag DN, Roller PP, Wilcox DE, Lyons BA. Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain. Journal of Molecular Recognition : Jmr. 20: 245-52. PMID 17705331 DOI: 10.1002/Jmr.834  0.724
2007 Mustra DJ, Warren AJ, Wilcox DE, Hamilton JW. Preferential binding of human XPA to the mitomycin C-DNA interstrand crosslink and modulation by arsenic and cadmium. Chemico-Biological Interactions. 168: 159-68. PMID 17512921 DOI: 10.1016/J.Cbi.2007.04.004  0.333
2006 Grossoehme NE, Akilesh S, Guerinot ML, Wilcox DE. Metal-binding thermodynamics of the histidine-rich sequence from the metal-transport protein IRT1 of Arabidopsis thaliana. Inorganic Chemistry. 45: 8500-8. PMID 17029360 DOI: 10.1021/Ic0606431  0.453
2006 Ge R, Zhang Y, Sun X, Watt RM, He QY, Huang JD, Wilcox DE, Sun H. Thermodynamic and kinetic aspects of metal binding to the histidine-rich protein, Hpn. Journal of the American Chemical Society. 128: 11330-1. PMID 16939237 DOI: 10.1021/Ja062589T  0.398
2005 Ivancic M, Spuches AM, Guth EC, Daugherty MA, Wilcox DE, Lyons BA. Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complex. Protein Science : a Publication of the Protein Society. 14: 1556-69. PMID 15930003 DOI: 10.1110/Ps.041102305  0.711
2005 Spuches AM, Kruszyna HG, Rich AM, Wilcox DE. Thermodynamics of the As(III)-thiol interaction: arsenite and monomethylarsenite complexes with glutathione, dihydrolipoic acid, and other thiol ligands. Inorganic Chemistry. 44: 2964-72. PMID 15819584 DOI: 10.1021/Ic048694Q  0.714
2002 Zhang Y, Wilcox DE. Thermodynamic and spectroscopic study of Cu(II) and Ni(II) binding to bovine serum albumin. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 7: 327-37. PMID 11935357 DOI: 10.1007/S00775-001-0302-6  0.396
2001 Wilcox DE, Schenk AD, Feldman BM, Xu Y. Oxidation of zinc-binding cysteine residues in transcription factor proteins. Antioxidants & Redox Signaling. 3: 549-64. PMID 11554444 DOI: 10.1089/15230860152542925  0.41
2000 Zhang Y, Akilesh S, Wilcox DE. Isothermal titration calorimetry measurements of Ni(II) and Cu(II) binding to His, GlyGlyHis, HisGlyHis, and bovine serum albumin: a critical evaluation. Inorganic Chemistry. 39: 3057-64. PMID 11196901 DOI: 10.1021/Ic000036S  0.51
1998 Kruszyna H, Magyar JS, Rochelle LG, Russell MA, Smith RP, Wilcox DE. Spectroscopic studies of nitric oxide (NO) interactions with cobalamins: reaction of NO with superoxocobalamin(III) likely accounts for cobalamin reversal of the biological effects of NO. The Journal of Pharmacology and Experimental Therapeutics. 285: 665-71. PMID 9580611  0.713
1995 Posewitz MC, Wilcox DE. Properties of the Sp1 zinc finger 3 peptide: coordination chemistry, redox reactions, and metal binding competition with metallothionein. Chemical Research in Toxicology. 8: 1020-8. PMID 8605284 DOI: 10.1021/Tx00050A005  0.457
1994 Jones WB, Elgren TE, Morelock MM, Elder RC, Wilcox DE. Technetium metallothionein: Spectroscopic and EXAFS study of 99TcO3+ binding to Zn7-metallothionein Inorganic Chemistry. 33: 5571-5578. DOI: 10.1021/Ic00102A034  0.368
1994 Wang S, Lee MH, Hausinger RP, Clark PA, Wilcox DE, Scott RA. Structure of the dinuclear active site of urease. X-ray absorption spectroscopic study of native and 2-mercaptoethanol-inhibited bacterial and plant enzymes Inorganic Chemistry. 33: 1589-1593. DOI: 10.1021/Ic00086A006  0.319
1992 Barrera JA, Wilcox DE. EPR study of the toluene solution properties of the chromium(III)-alkyl complexes [CpCrMeCl]2, [Cp*CrRCl]2 (R = Me, Et, CH2SiMe3), and [Cp*CrMeBr]2: Dimer-monomer equilibria in solution Inorganic Chemistry. 31: 1745-1752. DOI: 10.1021/Ic00036A005  0.311
1991 Wilcox DE, Aufdenkampe AK, Dillon KG, Kull F, Reed MF, Elgren TE, Posewitz MG, Ciardelli TL. Metal binding properties of native and modified metallothionein Journal of Inorganic Biochemistry. 43: 150. DOI: 10.1016/0162-0134(91)84144-X  0.449
1990 Clark PA, Wilcox DE, Scott RA. X-ray absorption spectroscopic evidence for binding of the competitive inhibitor 2-mercaptoethanol to the nickel sites of Jack Bean Urease. A new Ni-Ni interaction in the inhibited enzyme Inorganic Chemistry. 29: 579-581. DOI: 10.1021/Ic00329A002  0.384
1989 Elgren TE, Wilcox DE. A unique low frequency Raman band associated with metal binding to metallothionein. Biochemical and Biophysical Research Communications. 163: 1093-9. PMID 2528950 DOI: 10.1016/0006-291X(89)92333-4  0.401
1989 Westmoreland TD, Wilcox DE, Baldwin MJ, Mims WB, Solomon EI. Detailed spectroscopic analysis of half-met hemocyanins: Mixed-valent contributions to electronic properties and structure Journal of the American Chemical Society. 111: 6106-6123. DOI: 10.1021/Ja00198A019  0.615
1989 Wilcox D, Clark P. Structure and chemistry of the urease Ni(II) active site Journal of Inorganic Biochemistry. 36: 300. DOI: 10.1016/0162-0134(89)84450-2  0.319
1987 Desjardins SR, Wilcox DE, Musselman RL, Solomon EI. Polarized, single-crystal, electronic spectral studies of hexachlorodicuprate(2-): excited-state effects of binuclear interaction Inorganic Chemistry. 26: 288-300. DOI: 10.1021/Ic00249A017  0.386
1987 Desjardins SR, Wilcox DE, Musselman RL, Solomon EI. Polarized, single-crystal, electronic spectral studies of Cu2Cl6 2-: Excited-state effects of the binuclear interaction Inorganic Chemistry. 26: 288-300.  0.301
1985 Wilcox DE, Porras AG, Hwang YT, Lerch K, Winkler ME, Solomon EI. Substrate analog binding to the coupled binuclear copper active site in tyrosinase Journal of the American Chemical Society. 107: 4015-4027. DOI: 10.1021/Ja00299A043  0.515
1985 Wilcox DE, Porras AG, Hwang YT, Lerch K, Winkler ME, Solomon EI. Substrate analogue binding to the coupled binuclear copper active site in tyrosinase Journal of the American Chemical Society. 107: 4015-4027.  0.445
1984 WILCOX DE, LONG JR, SOLOMON EI. ChemInform Abstract: EPR STUDIES OF THE “EPR-NONDETECTABLE” MET DERIVATIVE OF HEMOCYANIN: PERTURBATIONS AND DISPLACEMENT OF THE ENDOGENOUS BRIDGE IN THE COUPLED BINUCLEAR COPPER ACTIVE SITE Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198428042  0.374
1984 Wilcox DE, Long JR, Solomon EI. EPR studies of the "EPR-nondetectable" met derivative of hemocyanin: perturbations and displacement of the endogenous bridge in the coupled binuclear copper active site Journal of the American Chemical Society. 106: 2186-2194. DOI: 10.1002/Chin.198428042  0.456
1982 Solomon EI, Eickman NC, Himmelwright RS, Hwang YT, Plon SE, Wilcox DE. The nature of the binuclear copper site in Limulus and other hemocyanins. Progress in Clinical and Biological Research. 81: 189-230. PMID 6289350  0.382
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