Christopher A. Ross - Publications

Affiliations: 
Psychiatry Johns Hopkins University School of Medicine, Baltimore, MD, United States 

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Eddings CR, Arbez N, Akimov S, Geva M, Hayden MR, Ross CA. Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor. Neurobiology of Disease. PMID 31108174 DOI: 10.1016/j.nbd.2019.05.009  0.48
2019 Nucifora LG, MacDonald ML, Lee BJ, Peters ME, Norris AL, Orsburn BC, Yang K, Gleason K, Margolis RL, Pevsner J, Tamminga CA, Sweet RA, Ross CA, Sawa A, Nucifora FC. Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia. The American Journal of Psychiatry. appiajp201918070864. PMID 31055969 DOI: 10.1176/appi.ajp.2019.18070864  0.32
2019 Arbez N, Roby E, Akimov S, Eddings C, Ren M, Wang X, Ross CA. Cysteamine Protects Neurons from Mutant Huntingtin Toxicity. Journal of Huntington's Disease. PMID 30856117 DOI: 10.3233/JHD-180312  0.48
2019 Kedaigle AJ, Fraenkel E, Atwal RS, Wu M, Gusella JF, MacDonald ME, Kaye JA, Finkbeiner S, Mattis VB, Tom CM, Svendsen C, King AR, Chen Y, Stocksdale JT, Lim RG, ... ... Ross CA, et al. Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites. Human Molecular Genetics. PMID 30768179 DOI: 10.1093/hmg/ddy430  0.48
2018 Ross CA, Margolis RL. Research Domain Criteria: Cutting Edge Neuroscience or Galen's Humors Revisited? Molecular Neuropsychiatry. 4: 158-163. PMID 30643789 DOI: 10.1159/000493685  0.32
2018 Hua J, Blair NIS, Paez A, Choe A, Barber AD, Brandt A, Lim IAL, Xu F, Kamath V, Pekar JJ, van Zijl PCM, Ross CA, Margolis RL. Altered functional connectivity between sub-regions in the thalamus and cortex in schizophrenia patients measured by resting state BOLD fMRI at 7T. Schizophrenia Research. PMID 30409697 DOI: 10.1016/j.schres.2018.10.016  0.32
2018 Bowie LE, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, Hung CLK, Patel S, Xia J, Hertz NT, Ross CA, Litchfield DW, Sipione S, Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987005 DOI: 10.1073/pnas.1801772115  0.48
2017 Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, ... Ross CA, et al. PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9. PMID 29212711 DOI: 10.1126/scitranslmed.aal2332  0.48
2017 Arbez N, Ratovitski T, Roby E, Chighladze E, Stewart J, Ren M, Wang X, Lavery DJ, Ross CA. Posttranslational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity. The Journal of Biological Chemistry. PMID 28972180 DOI: 10.1074/jbc.M117.782300  0.48
2017 Ross CA, Kronenbuerger M, Duan W, Margolis RL. Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies. Handbook of Clinical Neurology. 144: 15-28. PMID 28947113 DOI: 10.1016/B978-0-12-801893-4.00002-X  0.32
2017 Zhu S, Cordner ZA, Xiong J, Chiu CT, Artola A, Zuo Y, Nelson AD, Kim TY, Zaika N, Woolums BM, Hess EJ, Wang X, Chuang DM, Pletnikov MM, Jenkins PM, ... ... Ross CA, et al. Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America. PMID 28894008 DOI: 10.1073/pnas.1700689114  0.48
2017 Ratovitski T, O'Meally RN, Jiang M, Chaerkady R, Chighladze E, Stewart JC, Wang X, Arbez N, Roby E, Alexandris A, Duan W, Vijayvargia R, Seong IS, Lavery DJ, Cole RN, ... Ross CA, et al. Post-translational modifications (PTMs), identified on endogenous huntingtin, cluster within proteolytic domains between HEAT repeats. Journal of Proteome Research. PMID 28653853 DOI: 10.1021/acs.jproteome.6b00991  0.48
2017 Grima JC, Daigle JG, Arbez N, Cunningham KC, Zhang K, Ochaba J, Geater C, Morozko E, Stocksdale J, Glatzer JC, Pham JT, Ahmed I, Peng Q, Wadhwa H, Pletnikova O, ... ... Ross CA, et al. Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 94: 93-107.e6. PMID 28384479 DOI: 10.1016/j.neuron.2017.03.023  0.48
2016 Lee BJ, Marchionni L, Andrews CE, Norris AL, Nucifora LG, Wu YC, Wright RA, Pevsner J, Ross CA, Margolis RL, Sawa A, Nucifora FC. Analysis of differential gene expression mediated by clozapine in human postmortem brains. Schizophrenia Research. PMID 28038920 DOI: 10.1016/j.schres.2016.12.017  0.32
2016 Nucifora LG, Wu YC, Lee BJ, Sha L, Margolis RL, Ross CA, Sawa A, Nucifora FC. A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation. Molecular Neuropsychiatry. 2: 133-144. PMID 27867938 DOI: 10.1159/000447358  0.32
2016 Hua J, Brandt AS, Lee S, Blair NI, Wu Y, Lui S, Patel J, Faria AV, Lim IA, Unschuld PG, Pekar JJ, van Zijl PC, Ross CA, Margolis RL. Abnormal Grey Matter Arteriolar Cerebral Blood Volume in Schizophrenia Measured With 3D Inflow-Based Vascular-Space-Occupancy MRI at 7T. Schizophrenia Bulletin. PMID 27539951 DOI: 10.1093/schbul/sbw109  0.32
2016 Li PP, Sun X, Xia G, Arbez N, Paul S, Zhu S, Peng HB, Ross CA, Koeppen AH, Margolis RL, Pulst SM, Ashizawa T, Rudnicki DD. ATXN2-AS, a gene antisense to ATXN2, is associated with SCA2 and ALS. Annals of Neurology. PMID 27531668 DOI: 10.1002/ana.24761  0.48
2016 Ratovitski T, Chaerkady R, Kammers K, Stewart JC, Zavala A, Pletnikova O, Troncoso JC, Rudnicki DD, Margolis RL, Cole RN, Ross CA. Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains. Journal of Proteome Research. PMID 27486686 DOI: 10.1021/acs.jproteome.6b00448  0.32
2016 Nucifora FC, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, ... ... Ross CA, et al. Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. Nature Communications. 7: 11792. PMID 27273569 DOI: 10.1038/ncomms11792  0.48
2016 Meng X, Zhu S, Shevelkin A, Ross CA, Pletnikov M. DISC1, astrocytes and neuronal maturation: a possible mechanistic link with implications for mental disorders. Journal of Neurochemistry. PMID 27187935 DOI: 10.1111/jnc.13663  0.48
2016 Sun X, Ran D, Zhao X, Huang Y, Long S, Liang F, Guo W, Nucifora FC, Gu H, Lu X, Chen L, Zeng J, Ross CA, Pei Z. Melatonin attenuates hLRRK2-induced sleep disturbances and synaptic dysfunction in a Drosophila model of Parkinson's disease. Molecular Medicine Reports. PMID 26985725 DOI: 10.3892/mmr.2016.4991  0.48
2016 Brandt AS, Unschuld PG, Pradhan S, Lim IA, Churchill G, Harris AD, Hua J, Barker PB, Ross CA, van Zijl PC, Edden RA, Margolis RL. Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7Tesla. Schizophrenia Research. PMID 26925800 DOI: 10.1016/j.schres.2016.02.017  0.48
2015 Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MM, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, ... ... Ross CA, et al. PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Nature Medicine. PMID 26642438 DOI: 10.1038/nm.4003  0.48
2015 Bañez-Coronel M, Ayhan F, Tarabochia AD, Zu T, Perez BA, Tusi SK, Pletnikova O, Borchelt DR, Ross CA, Margolis RL, Yachnis AT, Troncoso JC, Ranum LP. RAN Translation in Huntington Disease. Neuron. 88: 667-77. PMID 26590344 DOI: 10.1016/j.neuron.2015.10.038  0.48
2015 Waldron-Roby E, Hoerauf J, Arbez N, Zhu S, Kulcsar K, Ross CA. Sox11 Reduces Caspase-6 Cleavage and Activity. Plos One. 10: e0141439. PMID 26505998 DOI: 10.1371/journal.pone.0141439  0.48
2015 O'Hearn EE, Hwang HS, Holmes SE, Rudnicki DD, Chung DW, Seixas AI, Cohen RL, Ross CA, Trojanowski JQ, Pletnikova O, Troncoso JC, Margolis RL. Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26340331 DOI: 10.1002/mds.26348  0.48
2015 Sun X, Li PP, Zhu S, Cohen R, Marque LO, Ross CA, Pulst SM, Chan HY, Margolis RL, Rudnicki DD. Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65. Scientific Reports. 5: 12521. PMID 26218986 DOI: 10.1038/srep12521  0.48
2015 Ratovitski T, Arbez N, Stewart JC, Chighladze E, Ross CA. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD). Cell Cycle (Georgetown, Tex.). 14: 1716-29. PMID 25927346 DOI: 10.1080/15384101.2015.1033595  0.48
2015 Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, et al. HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Human Molecular Genetics. 24: 3257-71. PMID 25740845 DOI: 10.1093/hmg/ddv080  0.48
2015 Jin J, Peng Q, Hou Z, Jiang M, Wang X, Langseth AJ, Tao M, Barker PB, Mori S, Bergles DE, Ross CA, Detloff PJ, Zhang J, Duan W. Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease. Human Molecular Genetics. 24: 2508-27. PMID 25609071 DOI: 10.1093/hmg/ddv016  0.48
2014 Paulsen JS, Long JD, Ross CA, Harrington DL, Erwin CJ, Williams JK, Westervelt HJ, Johnson HJ, Aylward EH, Zhang Y, Bockholt HJ, Barker RA. Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study. The Lancet. Neurology. 13: 1193-201. PMID 25453459 DOI: 10.1016/S1474-4422(14)70238-8  0.48
2014 Borchelt DR, Ross CA. Gabriele schilling (september 5, 1968-july 4, 2014. Journal of Huntington's Disease. 3: 225-7. PMID 25300326 DOI: 10.3233/JHD-149005  0.48
2014 Ross CA, Pantelyat A, Kogan J, Brandt J. Determinants of functional disability in Huntington's disease: role of cognitive and motor dysfunction. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1351-8. PMID 25216368 DOI: 10.1002/mds.26012  0.48
2014 Reilmann R, Leavitt BR, Ross CA. Huntington's disease: a field on the move. Introduction. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1333-4. PMID 25164859 DOI: 10.1002/mds.26017  0.48
2014 Reilmann R, Leavitt BR, Ross CA. Diagnostic criteria for Huntington's disease based on natural history. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1335-41. PMID 25164527 DOI: 10.1002/mds.26011  0.48
2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, ... ... Ross CA, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515: 414-8. PMID 25132547 DOI: 10.1038/nature13716  0.48
2014 Paulsen JS, Long JD, Johnson HJ, Aylward EH, Ross CA, Williams JK, Nance MA, Erwin CJ, Westervelt HJ, Harrington DL, Bockholt HJ, Zhang Y, McCusker EA, Chiu EM, Panegyres PK, et al. Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study. Frontiers in Aging Neuroscience. 6: 78. PMID 24795630 DOI: 10.3389/fnagi.2014.00078  0.48
2014 Ross CA, Aylward EH, Wild EJ, Langbehn DR, Long JD, Warner JH, Scahill RI, Leavitt BR, Stout JC, Paulsen JS, Reilmann R, Unschuld PG, Wexler A, Margolis RL, Tabrizi SJ. Huntington disease: natural history, biomarkers and prospects for therapeutics. Nature Reviews. Neurology. 10: 204-16. PMID 24614516 DOI: 10.1038/nrneurol.2014.24  0.48
2014 Watkin EE, Arbez N, Waldron-Roby E, O'Meally R, Ratovitski T, Cole RN, Ross CA. Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity. Plos One. 9: e88284. PMID 24505464 DOI: 10.1371/journal.pone.0088284  0.48
2014 Boudreau RL, Jiang P, Gilmore BL, Spengler RM, Tirabassi R, Nelson JA, Ross CA, Xing Y, Davidson BL. Transcriptome-wide discovery of microRNA binding sites in human brain. Neuron. 81: 294-305. PMID 24389009 DOI: 10.1016/j.neuron.2013.10.062  0.48
2014 Hua J, Unschuld PG, Margolis RL, van Zijl PC, Ross CA. Elevated arteriolar cerebral blood volume in prodromal Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 396-401. PMID 23847161 DOI: 10.1002/mds.25591  0.48
2014 Unschuld PG, Buchholz AS, Varvaris M, van Zijl PC, Ross CA, Pekar JJ, Hock C, Sweeney JA, Tamminga CA, Keshavan MS, Pearlson GD, Thaker GK, Schretlen DJ. Prefrontal brain network connectivity indicates degree of both schizophrenia risk and cognitive dysfunction. Schizophrenia Bulletin. 40: 653-64. PMID 23778975 DOI: 10.1093/schbul/sbt077  0.48
2014 Younes L, Ratnanather JT, Brown T, Aylward E, Nopoulos P, Johnson H, Magnotta VA, Paulsen JS, Margolis RL, Albin RL, Miller MI, Ross CA. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. Human Brain Mapping. 35: 792-809. PMID 23281100 DOI: 10.1002/hbm.22214  0.48
2013 Aylward EH, Harrington DL, Mills JA, Nopoulos PC, Ross CA, Long JD, Liu D, Westervelt HK, Paulsen JS. Regional atrophy associated with cognitive and motor function in prodromal Huntington disease. Journal of Huntington's Disease. 2: 477-89. PMID 25062732 DOI: 10.3233/JHD-130076  0.48
2013 Qin YY, Hsu JT, Yoshida S, Faria AV, Oishi K, Unschuld PG, Redgrave GW, Ying SH, Ross CA, van Zijl PC, Hillis AE, Albert MS, Lyketsos CG, Miller MI, Mori S, et al. Gross feature recognition of Anatomical Images based on Atlas grid (GAIA): Incorporating the local discrepancy between an atlas and a target image to capture the features of anatomic brain MRI. Neuroimage. Clinical. 3: 202-11. PMID 24179864 DOI: 10.1016/j.nicl.2013.08.006  0.48
2013 Unschuld PG, Liu X, Shanahan M, Margolis RL, Bassett SS, Brandt J, Schretlen DJ, Redgrave GW, Hua J, Hock C, Reading SA, van Zijl PC, Pekar JJ, Ross CA. Prefrontal executive function associated coupling relates to Huntington's disease stage. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 49: 2661-73. PMID 23906595 DOI: 10.1016/j.cortex.2013.05.015  0.48
2013 Vashishtha M, Ng CW, Yildirim F, Gipson TA, Kratter IH, Bodai L, Song W, Lau A, Labadorf A, Vogel-Ciernia A, Troncosco J, Ross CA, Bates GP, Krainc D, Sadri-Vakili G, et al. Targeting H3K4 trimethylation in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E3027-36. PMID 23872847 DOI: 10.1073/pnas.1311323110  0.48
2013 Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, et al. Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics. 14: 173-9. PMID 23644918 DOI: 10.1007/s10048-013-0364-y  0.48
2013 Holley SM, Wang EA, Cepeda C, Jentsch JD, Ross CA, Pletnikov MV, Levine MS. Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia. Schizophrenia Research. 146: 264-72. PMID 23481583 DOI: 10.1016/j.schres.2013.02.007  0.48
2013 Jin J, Albertz J, Guo Z, Peng Q, Rudow G, Troncoso JC, Ross CA, Duan W. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease. Journal of Neurochemistry. 125: 410-9. PMID 23373812 DOI: 10.1111/jnc.12190  0.48
2013 Chen H, Wang N, Zhao X, Ross CA, O'Shea KS, McInnis MG. Gene expression alterations in bipolar disorder postmortem brains. Bipolar Disorders. 15: 177-87. PMID 23360497 DOI: 10.1111/bdi.12039  0.48
2012 Cloud LJ, Rosenblatt A, Margolis RL, Ross CA, Pillai JA, Corey-Bloom J, Tully HM, Bird T, Panegyres PK, Nichter CA, Higgins DS, Helmers SL, Factor SA, Jones R, Testa CM. Seizures in juvenile Huntington's disease: frequency and characterization in a multicenter cohort. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1797-800. PMID 23124580 DOI: 10.1002/mds.25237  0.48
2012 Guo Z, Rudow G, Pletnikova O, Codispoti KE, Orr BA, Crain BJ, Duan W, Margolis RL, Rosenblatt A, Ross CA, Troncoso JC. Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1379-86. PMID 22975850 DOI: 10.1002/mds.25159  0.48
2012 Unschuld PG, Joel SE, Pekar JJ, Reading SA, Oishi K, McEntee J, Shanahan M, Bakker A, Margolis RL, Bassett SS, Rosenblatt A, Mori S, van Zijl PC, Ross CA, Redgrave GW. Depressive symptoms in prodromal Huntington's Disease correlate with Stroop-interference related functional connectivity in the ventromedial prefrontal cortex. Psychiatry Research. 203: 166-74. PMID 22974690 DOI: 10.1016/j.pscychresns.2012.01.002  0.48
2012 Ramos EM, Latourelle JC, Lee JH, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, et al. Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset. Human Genetics. 131: 1833-40. PMID 22825315 DOI: 10.1007/s00439-012-1205-z  0.48
2012 Lee JH, Lee JM, Ramos EM, Gillis T, Mysore JS, Kishikawa S, Hadzi T, Hendricks AE, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Gellera C, et al. TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease. Biochemical and Biophysical Research Communications. 424: 404-8. PMID 22771793 DOI: 10.1016/j.bbrc.2012.06.120  0.48
2012 Yang D, Li T, Liu Z, Arbez N, Yan J, Moran TH, Ross CA, Smith WW. LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin. Neurobiology of Disease. 47: 385-92. PMID 22668778 DOI: 10.1016/j.nbd.2012.05.020  0.48
2012 Unschuld PG, Edden RA, Carass A, Liu X, Shanahan M, Wang X, Oishi K, Brandt J, Bassett SS, Redgrave GW, Margolis RL, van Zijl PC, Barker PB, Ross CA. Brain metabolite alterations and cognitive dysfunction in early Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 895-902. PMID 22649062 DOI: 10.1002/mds.25010  0.48
2012 Fu J, Jin J, Cichewicz RH, Hageman SA, Ellis TK, Xiang L, Peng Q, Jiang M, Arbez N, Hotaling K, Ross CA, Duan W. trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease. The Journal of Biological Chemistry. 287: 24460-72. PMID 22648412 DOI: 10.1074/jbc.M112.382226  0.48
2012 Juopperi TA, Kim WR, Chiang CH, Yu H, Margolis RL, Ross CA, Ming GL, Song H. Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells. Molecular Brain. 5: 17. PMID 22613578 DOI: 10.1186/1756-6606-5-17  0.48
2012 Ratovitski T, Chighladze E, Arbez N, Boronina T, Herbrich S, Cole RN, Ross CA. Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis. Cell Cycle (Georgetown, Tex.). 11: 2006-21. PMID 22580459 DOI: 10.4161/cc.20423  0.48
2012 Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein. The Journal of Biological Chemistry. 287: 16017-28. PMID 22433867 DOI: 10.1074/jbc.M111.252577  0.48
2012 Unschuld PG, Joel SE, Liu X, Shanahan M, Margolis RL, Biglan KM, Bassett SS, Schretlen DJ, Redgrave GW, van Zijl PC, Pekar JJ, Ross CA. Impaired cortico-striatal functional connectivity in prodromal Huntington's Disease. Neuroscience Letters. 514: 204-9. PMID 22425717 DOI: 10.1016/j.neulet.2012.02.095  0.48
2012 Lee JM, Gillis T, Mysore JS, Ramos EM, Myers RH, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Griguoli A, Di Donato S, Gomez-Tortosa E, Ayuso C, et al. Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. American Journal of Human Genetics. 90: 434-44. PMID 22387017 DOI: 10.1016/j.ajhg.2012.01.005  0.48
2012 Seixas AI, Holmes SE, Takeshima H, Pavlovich A, Sachs N, Pruitt JL, Silveira I, Ross CA, Margolis RL, Rudnicki DD. Loss of junctophilin-3 contributes to Huntington disease-like 2 pathogenesis. Annals of Neurology. 71: 245-57. PMID 22367996 DOI: 10.1002/ana.22598  0.48
2012 Waldron-Roby E, Ratovitski T, Wang X, Jiang M, Watkin E, Arbez N, Graham RK, Hayden MR, Hou Z, Mori S, Swing D, Pletnikov M, Duan W, Tessarollo L, Ross CA. Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 183-93. PMID 22219281 DOI: 10.1523/JNEUROSCI.1305-11.2012  0.48
2012 Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, ... ... Ross CA, et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nature Medicine. 18: 153-8. PMID 22179319 DOI: 10.1038/nm.2558  0.48
2012 Rosenblatt A, Kumar BV, Mo A, Welsh CS, Margolis RL, Ross CA. Age, CAG repeat length, and clinical progression in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 272-6. PMID 22173986 DOI: 10.1002/mds.24024  0.48
2012 Aylward EH, Liu D, Nopoulos PC, Ross CA, Pierson RK, Mills JA, Long JD, Paulsen JS. Striatal volume contributes to the prediction of onset of Huntington disease in incident cases. Biological Psychiatry. 71: 822-8. PMID 21907324 DOI: 10.1016/j.biopsych.2011.07.030  0.48
2011 Reading SA, Oishi K, Redgrave GW, McEntee J, Shanahan M, Yoritomo N, Younes L, Mori S, Miller MI, van Zijl P, Margolis RL, Ross CA. Diffuse abnormality of low to moderately organized white matter in schizophrenia. Brain Connectivity. 1: 511-9. PMID 22500774 DOI: 10.1089/brain.2011.0041  0.32
2011 Aylward E, Mills J, Liu D, Nopoulos P, Ross CA, Pierson R, Paulsen JS. Association between Age and Striatal Volume Stratified by CAG Repeat Length in Prodromal Huntington Disease. Plos Currents. 3: RRN1235. PMID 21593963 DOI: 10.1371/currents.RRN1235  0.48
2011 Wang Y, Steimle PA, Ren Y, Ross CA, Robinson DN, Egelhoff TT, Sesaki H, Iijima M. Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation Molecular Biology of the Cell. 22: 2270-2281. PMID 21562226 DOI: 10.1091/mbc.E10-11-0926  0.48
2011 Rosenblatt A, Kumar BV, Margolis RL, Welsh CS, Ross CA. Factors contributing to institutionalization in patients with Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1711-6. PMID 21538527 DOI: 10.1002/mds.23716  0.48
2011 Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA. A compact beta model of huntingtin toxicity. The Journal of Biological Chemistry. 286: 8188-96. PMID 21209075 DOI: 10.1074/jbc.M110.192013  0.48
2011 Ross CA, Tabrizi SJ. Huntington's disease: from molecular pathogenesis to clinical treatment. The Lancet. Neurology. 10: 83-98. PMID 21163446 DOI: 10.1016/S1474-4422(10)70245-3  0.48
2011 Nopoulos PC, Aylward EH, Ross CA, Mills JA, Langbehn DR, Johnson HJ, Magnotta VA, Pierson RK, Beglinger LJ, Nance MA, Barker RA, Paulsen JS. Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment. Brain : a Journal of Neurology. 134: 137-42. PMID 20923788 DOI: 10.1093/brain/awq280  0.48
2011 Aylward EH, Nopoulos PC, Ross CA, Langbehn DR, Pierson RK, Mills JA, Johnson HJ, Magnotta VA, Juhl AR, Paulsen JS. Longitudinal change in regional brain volumes in prodromal Huntington disease. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 405-10. PMID 20884680 DOI: 10.1136/jnnp.2010.208264  0.48
2010 Abazyan B, Nomura J, Kannan G, Ishizuka K, Tamashiro KL, Nucifora F, Pogorelov V, Ladenheim B, Yang C, Krasnova IN, Cadet JL, Pardo C, Mori S, Kamiya A, Vogel MW, ... ... Ross CA, et al. Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. Biological Psychiatry. 68: 1172-81. PMID 21130225 DOI: 10.1016/j.biopsych.2010.09.022  0.48
2010 Duan W, Ross CA. Potential therapeutic targets for neurodegenerative diseases: Lessons learned from calorie restriction Current Drug Targets. 11: 1281-1292. PMID 20840070  0.48
2010 Nopoulos PC, Aylward EH, Ross CA, Johnson HJ, Magnotta VA, Juhl AR, Pierson RK, Mills J, Langbehn DR, Paulsen JS. Cerebral cortex structure in prodromal Huntington disease. Neurobiology of Disease. 40: 544-54. PMID 20688164 DOI: 10.1016/j.nbd.2010.07.014  0.48
2010 Duff K, Paulsen JS, Beglinger LJ, Langbehn DR, Wang C, Stout JC, Ross CA, Aylward E, Carlozzi NE, Queller S. "Frontal" behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness. The Journal of Neuropsychiatry and Clinical Neurosciences. 22: 196-207. PMID 20463114 DOI: 10.1176/appi.neuropsych.22.2.196  0.48
2010 Jiang M, Porat-Shliom Y, Pei Z, Cheng Y, Xiang L, Sommers K, Li Q, Gillardon F, Hengerer B, Berlinicke C, Smith WW, Zack DJ, Poirier MA, Ross CA, Duan W. Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. Journal of Neurochemistry. 114: 419-29. PMID 20412383 DOI: 10.1111/j.1471-4159.2010.06752.x  0.48
2010 Paulsen JS, Nopoulos PC, Aylward E, Ross CA, Johnson H, Magnotta VA, Juhl A, Pierson RK, Mills J, Langbehn D, Nance M. Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Research Bulletin. 82: 201-7. PMID 20385209 DOI: 10.1016/j.brainresbull.2010.04.003  0.48
2010 Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. Human Molecular Genetics. 19: 2087-98. PMID 20185556 DOI: 10.1093/hmg/ddq086  0.48
2010 Margolis RL, Ross CA. Neuronal signaling pathways: genetic insights into the pathophysiology of major mental illness. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 350-1. PMID 20010716 DOI: 10.1038/npp.2009.137  0.48
2010 Zhang J, Peng Q, Li Q, Jahanshad N, Hou Z, Jiang M, Masuda N, Langbehn DR, Miller MI, Mori S, Ross CA, Duan W. Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. Neuroimage. 49: 2340-51. PMID 19850133 DOI: 10.1016/j.neuroimage.2009.10.027  0.48
2009 Bruce HA, Sachs N, Rudnicki DD, Lin SG, Willour VL, Cowell JK, Conroy J, McQuaid DE, Rossi M, Gaile DP, Nowak NJ, Holmes SE, Sklar P, Ross CA, Delisi LE, et al. Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations. Psychiatric Genetics. 19: 64-71. PMID 19672138 DOI: 10.1097/YPG.0b013e3283207ff6  0.48
2009 Biglan KM, Ross CA, Langbehn DR, Aylward EH, Stout JC, Queller S, Carlozzi NE, Duff K, Beglinger LJ, Paulsen JS. Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1763-72. PMID 19562761 DOI: 10.1002/mds.22601  0.48
2009 Ross CA, Margolis RL. Schizophrenia: A point of disruption. Nature. 458: 976-7. PMID 19396131 DOI: 10.1038/458976a  0.48
2009 Ayhan Y, Sawa A, Ross CA, Pletnikov MV. Animal models of gene-environment interactions in schizophrenia. Behavioural Brain Research. 204: 274-81. PMID 19379776 DOI: 10.1016/j.bbr.2009.04.010  0.48
2009 Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL. CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proceedings of the National Academy of Sciences of the United States of America. 106: 2897-902. PMID 19196961 DOI: 10.1073/pnas.0810123106  0.48
2009 Sato T, Miura M, Yamada M, Yoshida T, Wood JD, Yazawa I, Masuda M, Suzuki T, Shin RM, Yau HJ, Liu FC, Shimohata T, Onodera O, Ross CA, Katsuki M, et al. Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice. Human Molecular Genetics. 18: 723-36. PMID 19039037 DOI: 10.1093/hmg/ddn403  0.48
2009 Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT. Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain Human Molecular Genetics. 18: 391-404. PMID 18996920 DOI: 10.1093/hmg/ddn361  0.48
2008 Brandt J, Inscore AB, Ward J, Shpritz B, Rosenblatt A, Margolis RL, Ross CA. Neuropsychological deficits in Huntington's disease gene carriers and correlates of early "conversion". The Journal of Neuropsychiatry and Clinical Neurosciences. 20: 466-72. PMID 19196932 DOI: 10.1176/appi.neuropsych.20.4.466  0.48
2008 Liu M, Liang Y, Chigurupati S, Lathia JD, Pletnikov M, Sun Z, Crow M, Ross CA, Mattson MP, Rabb H. Acute kidney injury leads to inflammation and functional changes in the brain. Journal of the American Society of Nephrology : Jasn. 19: 1360-70. PMID 18385426 DOI: 10.1681/ASN.2007080901  0.4
2008 Rudnicki DD, Pletnikova O, Vonsattel JP, Ross CA, Margolis RL. A comparison of huntington disease and huntington disease-like 2 neuropathology. Journal of Neuropathology and Experimental Neurology. 67: 366-74. PMID 18379432 DOI: 10.1097/NEN.0b013e31816b4aee  0.48
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, ... ... Ross CA, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/j.biopsych.2008.03.005  0.48
2008 Liu Z, Wang X, Yu Y, Li X, Wang T, Jiang H, Ren Q, Jiao Y, Sawa A, Moran T, Ross CA, Montell C, Smith WW. A Drosophila model for LRRK2-linked parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 105: 2693-8. PMID 18258746 DOI: 10.1073/pnas.0708452105  0.48
2008 Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H, Giese A. Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. The Journal of Biological Chemistry. 283: 10992-1003. PMID 18258594 DOI: 10.1074/jbc.M709634200  0.48
2007 Ratovitski T, Nakamura M, D'Ambola J, Chighladze E, Liang Y, Wang W, Graham R, Hayden MR, Borchelt DR, Hirschhorn RR, Ross CA. N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington's disease. Cell Cycle (Georgetown, Tex.). 6: 2970-81. PMID 18156806  0.48
2007 Williams RB, Gutekunst WR, Joyner PM, Duan W, Li Q, Ross CA, Williams TD, Cichewicz RH. Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and alpha-synuclein toxicity. Journal of Agricultural and Food Chemistry. 55: 9450-6. PMID 17944533 DOI: 10.1021/jf072241x  0.48
2007 Colomer Gould VF, Goti D, Pearce D, Gonzalez GA, Gao H, Bermudez de Leon M, Jenkins NA, Copeland NG, Ross CA, Brown DR. A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice. Neurobiology of Disease. 27: 362-9. PMID 17632007 DOI: 10.1016/j.nbd.2007.06.005  0.48
2007 Johnson SA, Stout JC, Solomon AC, Langbehn DR, Aylward EH, Cruce CB, Ross CA, Nance M, Kayson E, Julian-Baros E, Hayden MR, Kieburtz K, Guttman M, Oakes D, Shoulson I, et al. Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease. Brain : a Journal of Neurology. 130: 1732-44. PMID 17584778 DOI: 10.1093/brain/awm107  0.48
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