Ira Mellman - Publications

Affiliations: 
Yale, Genetech 
Area:
Membrane transport in cells
Website:
http://www.gene.com/scientists/our-scientists/ira-mellman

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel Iii EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, ... ... Mellman I, et al. TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature. PMID 29443960 DOI: 10.1038/nature25501  0.4
2016 Ebert PJ, Cheung J, Yang Y, McNamara E, Hong R, Moskalenko M, Gould SE, Maecker H, Irving BA, Kim JM, Belvin M, Mellman I. MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade. Immunity. PMID 26944201 DOI: 10.1016/j.immuni.2016.01.024  1
2015 Belvin M, Mellman I. Is all cancer therapy immunotherapy? Science Translational Medicine. 7: 315fs48. PMID 26606965 DOI: 10.1126/scitranslmed.aad7661  1
2015 Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C, Peng I, Jeet S, Wu LC, Mellman I, Delamarre L, Austin CD. Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26561586 DOI: 10.1073/pnas.1520627112  1
2015 Delamarre L, Mellman I, Yadav M. Cancer immunotherapy. Neo approaches to cancer vaccines. Science (New York, N.Y.). 348: 760-1. PMID 25977539 DOI: 10.1126/science.aab3465  1
2015 Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren KJ, McInerney GM, Karlsson Hedestam GB, Mellman I, Smed-Sörensen A. Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. Journal of Immunology (Baltimore, Md. : 1950). 194: 4422-30. PMID 25801434 DOI: 10.4049/jimmunol.1402671  1
2015 Fu C, Liang X, Cui W, Ober-Blöbaum JL, Vazzana J, Shrikant PA, Lee KP, Clausen BE, Mellman I, Jiang A. β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10. Proceedings of the National Academy of Sciences of the United States of America. 112: 2823-8. PMID 25730849 DOI: 10.1073/pnas.1414167112  1
2015 Reversat A, Yuseff MI, Lankar D, Malbec O, Obino D, Maurin M, Penmatcha NV, Amoroso A, Sengmanivong L, Gundersen GG, Mellman I, Darchen F, Desnos C, Pierobon P, Lennon-Duménil AM. Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse. Molecular Biology of the Cell. 26: 1273-85. PMID 25631815 DOI: 10.1091/mbc.E14-09-1373  1
2015 Chung I, Mellman I. Single-molecule optical methods analyzing receptor tyrosine kinase activation in living cells. Methods in Molecular Biology (Clifton, N.J.). 1233: 35-44. PMID 25319887 DOI: 10.1007/978-1-4939-1789-1_4  1
2015 Topalian SL, Wolchok JD, Chan TA, Mellman I, Palucka K, Banchereau J, Rosenberg SA, Wittrup KD. Immunotherapy: The path to win the war on cancer? Cell. 161: 185-186. DOI: 10.1016/j.cell.2015.03.045  1
2014 Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR, Delamarre L. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 515: 572-6. PMID 25428506 DOI: 10.1038/nature14001  1
2014 Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, ... ... Mellman I, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 515: 563-7. PMID 25428504 DOI: 10.1038/nature14011  1
2014 Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Mazière A, Klumperman J, Schlatter M, Delamarre L, Mellman I. Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature. 509: 240-4. PMID 24695226 DOI: 10.1038/nature13133  1
2014 Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nature Immunology. 15: 161-7. PMID 24362890 DOI: 10.1038/ni.2795  1
2014 Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⁺ T cells. Journal of Leukocyte Biology. 95: 179-90. PMID 24023259 DOI: 10.1189/jlb.0613330  1
2013 Mellman I. Dendritic cells: master regulators of the immune response. Cancer Immunology Research. 1: 145-9. PMID 24777676 DOI: 10.1158/2326-6066.CIR-13-0102  1
2013 Mellman I, Yarden Y. Endocytosis and cancer. Cold Spring Harbor Perspectives in Biology. 5: a016949. PMID 24296170 DOI: 10.1101/cshperspect.a016949  1
2013 Mellman I, Emr SD. A Nobel Prize for membrane traffic: vesicles find their journey's end. The Journal of Cell Biology. 203: 559-61. PMID 24215073 DOI: 10.1083/jcb.201310134  1
2013 Sliwkowski MX, Mellman I. Antibody therapeutics in cancer. Science (New York, N.Y.). 341: 1192-8. PMID 24031011 DOI: 10.1126/science.1241145  1
2013 Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 39: 1-10. PMID 23890059 DOI: 10.1016/j.immuni.2013.07.012  1
2013 Oh J, Wu N, Baravalle G, Cohn B, Ma J, Lo B, Mellman I, Ishido S, Anderson M, Shin JS. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. The Journal of Experimental Medicine. 210: 1069-77. PMID 23712430 DOI: 10.1084/jem.20122695  1
2013 Cohn L, Chatterjee B, Esselborn F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L. Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation. The Journal of Experimental Medicine. 210: 1049-63. PMID 23569326 DOI: 10.1084/jem.20121251  1
2012 Lo B, Strasser G, Sagolla M, Austin CD, Junttila M, Mellman I. Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways. The Journal of Cell Biology. 199: 1117-30. PMID 23266956 DOI: 10.1083/jcb.201208080  1
2012 Chatterjee B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I. Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 120: 2011-20. PMID 22791285 DOI: 10.1182/blood-2012-01-402370  1
2012 Mellman I. Profile of Ira Mellman. Interview by Prashant Nair. Proceedings of the National Academy of Sciences of the United States of America. 109: 8790-2. PMID 22645337 DOI: 10.1073/pnas.1207791109  1
2012 Ma JK, Platt MY, Eastham-Anderson J, Shin JS, Mellman I. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length. Proceedings of the National Academy of Sciences of the United States of America. 109: 8820-7. PMID 22566640 DOI: 10.1073/pnas.1202977109  1
2012 Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, ... Mellman I, et al. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5299-304. PMID 22431598 DOI: 10.1073/pnas.1116510109  1
2012 Smed-Sörensen A, Chalouni C, Chatterjee B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I. Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. Plos Pathogens. 8: e1002572. PMID 22412374 DOI: 10.1371/journal.ppat.1002572  1
2011 Banchereau J, Cohn F, Inaba K, Muller B, Mellman I, Nathan C, Nussenzweig M, O'Garra A, Seder B, Schuler G, Sher A. Remembering Ralph Steinman. The Journal of Experimental Medicine. 208: 2343-7. PMID 22216461 DOI: 10.1084/jem.20112295  1
2011 Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature. 480: 480-9. PMID 22193102 DOI: 10.1038/nature10673  1
2011 Mellman I, Nussenzweig M. Retrospective. Ralph M. Steinman (1943-2011). Science (New York, N.Y.). 334: 466. PMID 22034425 DOI: 10.1126/science.1215136  1
2011 Nussenzweig MC, Mellman I. Ralph Steinman (1943-2011). Nature. 478: 460. PMID 22031432 DOI: 10.1038/478460a  1
2011 Francis SS, Sfakianos J, Lo B, Mellman I. A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. The Journal of Cell Biology. 193: 219-33. PMID 21444686 DOI: 10.1083/jcb.201009001  1
2011 Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane. The Journal of Biological Chemistry. 286: 16879-90. PMID 21383016 DOI: 10.1074/jbc.M110.186932  1
2010 Mellman I. Cell biology redux. Molecular Biology of the Cell. 21: 3809-10. PMID 21079023 DOI: 10.1091/mbc.E10-04-0346  1
2010 Palucka K, Banchereau J, Mellman I. Designing vaccines based on biology of human dendritic cell subsets. Immunity. 33: 464-78. PMID 21029958 DOI: 10.1016/j.immuni.2010.10.007  1
2010 Togawa A, Sfakianos J, Ishibe S, Suzuki S, Fujigaki Y, Kitagawa M, Mellman I, Cantley LG. Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly. Biochemical and Biophysical Research Communications. 400: 271-7. PMID 20728428 DOI: 10.1016/j.bbrc.2010.08.060  1
2010 Mellman I, Clausen BE. Immunology. Beta-catenin balances immunity. Science (New York, N.Y.). 329: 767-9. PMID 20705838 DOI: 10.1126/science.1194185  1
2010 McCurley N, Mellman I. Monocyte-derived dendritic cells exhibit increased levels of lysosomal proteolysis as compared to other human dendritic cell populations. Plos One. 5: e11949. PMID 20689855 DOI: 10.1371/journal.pone.0011949  1
2010 Winckler B, Mellman I. Trafficking guidance receptors. Cold Spring Harbor Perspectives in Biology. 2: a001826. PMID 20504966 DOI: 10.1101/cshperspect.a001826  1
2010 Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature. 464: 783-7. PMID 20208517 DOI: 10.1038/nature08827  1
2010 Mellman I, Cresswell P. Antigen processing and presentation. Current Opinion in Immunology. 22: 78-80. PMID 20172702 DOI: 10.1016/j.coi.2010.01.013  1
2010 Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML. Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Developmental Cell. 18: 39-51. PMID 20152176 DOI: 10.1016/j.devcel.2009.12.006  1
2010 Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L. Mature dendritic cells use endocytic receptors to capture and present antigens. Proceedings of the National Academy of Sciences of the United States of America. 107: 4287-92. PMID 20142498 DOI: 10.1073/pnas.0910609107  1
2009 Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, Mellman I, Prindiville SA, Viner JL, Weiner LM, Matrisian LM. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5323-37. PMID 19723653 DOI: 10.1158/1078-0432.CCR-09-0737  1
2009 Farr GA, Hull M, Mellman I, Caplan MJ. Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. The Journal of Cell Biology. 186: 269-82. PMID 19620635 DOI: 10.1083/jcb.200901021  1
2009 Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine. 27: 3013-21. PMID 19428913 DOI: 10.1016/j.vaccine.2009.03.034  1
2009 Becker SM, Delamarre L, Mellman I, Andrews NW. Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells. Immunobiology. 214: 495-505. PMID 19157638 DOI: 10.1016/j.imbio.2008.11.006  1
2009 Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. The Journal of Experimental Medicine. 206: 399-410. PMID 19153244 DOI: 10.1084/jem.20082108  1
2009 Mao YS, Yamaga M, Zhu X, Wei Y, Sun HQ, Wang J, Yun M, Wang Y, Di Paolo G, Bennett M, Mellman I, Abrams CS, De Camilli P, Lu CY, Yin HL. Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. The Journal of Cell Biology. 184: 281-96. PMID 19153220 DOI: 10.1083/jcb.200806121  1
2009 Mellman I. By the scientists, for the scientists. The Journal of Cell Biology. 184: 7-9. PMID 19139258 DOI: 10.1083/jcb.200812145  1
2008 Mellman I, Nelson WJ. Coordinated protein sorting, targeting and distribution in polarized cells. Nature Reviews. Molecular Cell Biology. 9: 833-45. PMID 18946473 DOI: 10.1038/nrm2525  1
2008 Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells. Traffic (Copenhagen, Denmark). 9: 1915-24. PMID 18764819 DOI: 10.1111/j.1600-0854.2008.00805.x  1
2008 Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (London, England). 3: 343-55. PMID 18510429 DOI: 10.2217/17435889.3.3.343  1
2008 Bloom O, Unternaehrer JJ, Jiang A, Shin JS, Delamarre L, Allen P, Mellman I. Spinophilin participates in information transfer at immunological synapses. The Journal of Cell Biology. 181: 203-11. PMID 18411312 DOI: 10.1083/jcb.200711149  1
2008 Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, Xue Y, Mellman I, Banchereau J, Connolly JE. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nature Immunology. 9: 551-7. PMID 18376401 DOI: 10.1038/ni.1602  1
2008 Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD. A33 antigen displays persistent surface expression. Cancer Immunology, Immunotherapy : Cii. 57: 1017-27. PMID 18236042 DOI: 10.1007/s00262-007-0433-x  1
2008 Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, Flavell RA, Mellman I, van der Goot FG. Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cellular Microbiology. 10: 1190-207. PMID 18194483 DOI: 10.1111/j.1462-5822.2008.01121.x  1
2007 Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody. Neoplasia (New York, N.Y.). 9: 1099-110. PMID 18084617 DOI: 10.1593/neo.07721  1
2007 Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L, Toomre D, Mellman I. Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. The Journal of Cell Biology. 179: 1133-40. PMID 18070914 DOI: 10.1083/jcb.200709111  1
2007 Jiang A, Bloom O, Ono S, Cui W, Unternaehrer J, Jiang S, Whitney JA, Connolly J, Banchereau J, Mellman I. Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity. 27: 610-24. PMID 17936032 DOI: 10.1016/j.immuni.2007.08.015  1
2007 Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, Homey B, Cao W, Wang YH, Su B, Nestle FO, Zal T, Mellman I, Schröder JM, Liu YJ, Gilliet M. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 449: 564-9. PMID 17873860 DOI: 10.1038/nature06116  1
2007 Mellman I. Private lives: reflections and challenges in understanding the cell biology of the immune system. Science (New York, N.Y.). 317: 625-7. PMID 17673653 DOI: 10.1126/science.1142955  1
2007 Rossner M, Mellman I. How the rich get richer. The Journal of Experimental Medicine. 204: 1503. PMID 17576780 DOI: 10.1084/jem.20071102  1
2007 Rossner M, Mellman I. How the rich get richer. The Journal of Cell Biology. 177: 951. PMID 17562793 DOI: 10.1083/jcb.200705199  1
2007 Mellman I. Ira Mellman: from endosomes to industry. Interview by William A Wells. The Journal of Cell Biology. 177: 570-1. PMID 17517958 DOI: 10.1083/jcb.1774pi  1
2007 Mellman I. Incomplete screening? Nature Immunology. 8: 473. PMID 17440454 DOI: 10.1038/ni0507-473  1
2007 Unternaehrer JJ, Chow A, Pypaert M, Inaba K, Mellman I. The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proceedings of the National Academy of Sciences of the United States of America. 104: 234-9. PMID 17190803 DOI: 10.1073/pnas.0609665104  1
2007 Schuck S, Gerl MJ, Ang A, Manninen A, Keller P, Mellman I, Simons K. Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic (Copenhagen, Denmark). 8: 47-60. PMID 17132146 DOI: 10.1111/j.1600-0854.2006.00506.x  1
2006 Mellman I. Bringing science to cancer therapy. The Yale Journal of Biology and Medicine. 79: 177-8. PMID 17940629  1
2006 Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature. 444: 115-8. PMID 17051151 DOI: 10.1038/nature05261  1
2006 Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA. Modulation of cell adhesion and motility in the immune system by Myo1f. Science (New York, N.Y.). 314: 136-9. PMID 17023661 DOI: 10.1126/science.1131920  1
2006 Delamarre L, Couture R, Mellman I, Trombetta ES. Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. The Journal of Experimental Medicine. 203: 2049-55. PMID 16908625 DOI: 10.1084/jem.20052442  1
2006 Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S. CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. The Journal of Cell Biology. 172: 1045-56. PMID 16567502 DOI: 10.1083/jcb.200509041  1
2006 Hua W, Sheff D, Toomre D, Mellman I. Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging. The Journal of Cell Biology. 172: 1035-44. PMID 16567501 DOI: 10.1083/jcb.200512012  1
2006 Zwickey HL, Unternaehrer JJ, Mellman I. Presentation of self-antigens on MHC class II molecules during dendritic cell maturation. International Immunology. 18: 199-209. PMID 16361313 DOI: 10.1093/intimm/dxh363  1
2006 Mellman I. Ira Mellman responds [3] Scientist. 20: 15.  1
2006 Mellman I. Where next for cancer immunotherap Scientist. 20: 47-53.  1
2005 Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, ... Mellman I, et al. Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 123: 157-70. PMID 16213220 DOI: 10.1016/j.cell.2005.08.018  1
2005 Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I. Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. The Journal of Cell Biology. 170: 595-605. PMID 16087710 DOI: 10.1083/jcb.200506051  1
2005 Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ. Targeting antigen to CD19 on B cells efficiently activates T cells. International Immunology. 17: 869-77. PMID 15967786 DOI: 10.1093/intimm/dxh266  1
2005 Mellman I. Antigen processing and presentation by dendritic cells: cell biological mechanisms. Advances in Experimental Medicine and Biology. 560: 63-7. PMID 15932021 DOI: 10.1007/0-387-24180-9_9  1
2005 Johns TG, Mellman I, Cartwright GA, Ritter G, Old LJ, Burgess AW, Scott AM. The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 780-2. PMID 15774576 DOI: 10.1096/fj.04-1766fje  1
2005 Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annual Review of Immunology. 23: 975-1028. PMID 15771591 DOI: 10.1146/annurev.immunol.22.012703.104538  1
2005 Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science (New York, N.Y.). 307: 1630-4. PMID 15761154 DOI: 10.1126/science.1108003  1
2005 Chow AY, Mellman I. Old lysosomes, new tricks: MHC II dynamics in DCs. Trends in Immunology. 26: 72-8. PMID 15668121 DOI: 10.1016/j.it.2004.11.008  1
2005 Mellman I. Fifty years of cell biology Journal of Cell Biology. 168: 15. DOI: 10.1083/jcb.200412045  1
2005 Chow AY, Unternaehrer JJ, Mellman I. MHC Class II Measuring Immunity: Basic Biology and Clinical Assessment. 12-22. DOI: 10.1016/B978-012455900-4/50264-6  1
2004 Ang AL, Taguchi T, Francis S, Fölsch H, Murrells LJ, Pypaert M, Warren G, Mellman I. Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells. The Journal of Cell Biology. 167: 531-43. PMID 15534004 DOI: 10.1083/jcb.200408165  1
2004 Meyer zum Bueschenfelde CO, Unternaehrer J, Mellman I, Bottomly K. Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 6119-24. PMID 15528348  1
2004 Matsuo M, Nagata Y, Sato E, Atanackovic D, Valmori D, Chen YT, Ritter G, Mellman I, Old LJ, Gnjatic S. IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation. Proceedings of the National Academy of Sciences of the United States of America. 101: 14467-72. PMID 15383663 DOI: 10.1073/pnas.0405947101  1
2004 Steinman RM, Mellman I. The JEM and the JCB: a synergistic partnership. The Journal of Cell Biology. 166: 611. PMID 15337771 DOI: 10.1083/jcb.200408039  1
2004 Steinman RM, Mellman I. Immunotherapy: bewitched, bothered, and bewildered no more. Science (New York, N.Y.). 305: 197-200. PMID 15247468 DOI: 10.1126/science.1099688  1
2004 Duffield A, Fölsch H, Mellman I, Caplan MJ. Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic (Copenhagen, Denmark). 5: 449-61. PMID 15117319 DOI: 10.1111/j.1398-9219.2004.00192.x  1
2004 Chang HC, Hull M, Mellman I. The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. The Journal of Cell Biology. 164: 1055-64. PMID 15051737 DOI: 10.1083/jcb.200311084  1
2004 Yeaman C, Ayala MI, Wright JR, Bard F, Bossard C, Ang A, Maeda Y, Seufferlein T, Mellman I, Nelson WJ, Malhotra V. Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nature Cell Biology. 6: 106-12. PMID 14743217 DOI: 10.1038/ncb1090  1
2004 Mellman I. Another evolutionary for the JCB Journal of Cell Biology. 167: 17. DOI: 10.1083/jcb.200409039  1
2004 Mellman I. Providing realistic access Journal of Cell Biology. 165: 19-20. DOI: 10.1083/jcb.200403076  1
2003 Fölsch H, Pypaert M, Maday S, Pelletier L, Mellman I. The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains. The Journal of Cell Biology. 163: 351-62. PMID 14581457 DOI: 10.1083/jcb.200309020  1
2003 Ang AL, Fölsch H, Koivisto UM, Pypaert M, Mellman I. The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. The Journal of Cell Biology. 163: 339-50. PMID 14581456 DOI: 10.1083/jcb.200307046  1
2003 Delamarre L, Holcombe H, Mellman I. Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation. The Journal of Experimental Medicine. 198: 111-22. PMID 12835477 DOI: 10.1084/jem.20021542  1
2003 Mellman I, Misteli T. Computational cell biology. The Journal of Cell Biology. 161: 463-4. PMID 12743098 DOI: 10.1083/jcb.200303202  1
2003 Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I. Activation of lysosomal function during dendritic cell maturation. Science (New York, N.Y.). 299: 1400-3. PMID 12610307 DOI: 10.1126/science.1080106  1
2002 Chang HC, Newmyer SL, Hull MJ, Ebersold M, Schmid SL, Mellman I. Hsc70 is required for endocytosis and clathrin function in Drosophila. The Journal of Cell Biology. 159: 477-87. PMID 12427870 DOI: 10.1083/jcb.200205086  1
2002 Holcombe H, Mellman I, Janeway CA, Bottomly K, Dittel BN. The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4982-9. PMID 12391212  1
2002 Chow A, Toomre D, Garrett W, Mellman I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 418: 988-94. PMID 12198549 DOI: 10.1038/nature01006  1
2002 Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett W, Old LJ, Mellman I. Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. Proceedings of the National Academy of Sciences of the United States of America. 99: 10629-34. PMID 12138174 DOI: 10.1073/pnas.112331099  1
2002 Sugimoto H, Sugahara M, Fölsch H, Koide Y, Nakatsu F, Tanaka N, Nishimura T, Furukawa M, Mullins C, Nakamura N, Mellman I, Ohno H. Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells. Molecular Biology of the Cell. 13: 2374-82. PMID 12134076 DOI: 10.1091/mbc.E01-10-0096  1
2002 Sheff D, Pelletier L, O'Connell CB, Warren G, Mellman I. Transferrin receptor recycling in the absence of perinuclear recycling endosomes. The Journal of Cell Biology. 156: 797-804. PMID 11877458 DOI: 10.1083/jcb.20111048  1
2002 Sheff DR, Kroschewski R, Mellman I. Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes. Molecular Biology of the Cell. 13: 262-75. PMID 11809838 DOI: 10.1091/mbc.01-07-0320  1
2001 Balamuth F, Leitenberg D, Unternaehrer J, Mellman I, Bottomly K. Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells. Immunity. 15: 729-38. PMID 11728335 DOI: 10.1016/S1074-7613(01)00223-0  1
2001 Mellman I, Steinman RM. Dendritic cells: specialized and regulated antigen processing machines. Cell. 106: 255-8. PMID 11509172 DOI: 10.1016/S0092-8674(01)00449-4  1
2001 Koivisto UM, Hubbard AL, Mellman I. A novel cellular phenotype for familial hypercholesterolemia due to a defect in polarized targeting of LDL receptor. Cell. 105: 575-85. PMID 11389828 DOI: 10.1016/S0092-8674(01)00371-3  1
2001 Mellman I. Setting logical priorities. Nature. 410: 1026. PMID 11323641 DOI: 10.1038/35074213  1
2001 Mellman I. Considerations in creating online archives. Science (New York, N.Y.). 292: 51. PMID 11294211  1
2001 Fölsch H, Pypaert M, Schu P, Mellman I. Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells. The Journal of Cell Biology. 152: 595-606. PMID 11157985  1
2001 Mellman I. Cell biology's journal gets a new look Journal of Cell Biology. 154: 9. DOI: 10.1083/jcb.200106064  1
2000 Fong DC, Brauweiler A, Minskoff SA, Bruhns P, Tamir I, Mellman I, Daeron M, Cambier JC. Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling. Journal of Immunology (Baltimore, Md. : 1950). 165: 4453-62. PMID 11035084  1
2000 Garrett WS, Chen LM, Kroschewski R, Ebersold M, Turley S, Trombetta S, Galán JE, Mellman I. Developmental control of endocytosis in dendritic cells by Cdc42. Cell. 102: 325-34. PMID 10975523  1
2000 Mellman I. Genomics comes to cell biology. The Journal of Cell Biology. 150: F21-2. PMID 10908581  1
2000 Turley SJ, Inaba K, Garrett WS, Ebersold M, Unternaehrer J, Steinman RM, Mellman I. Transport of peptide-MHC class II complexes in developing dendritic cells. Science (New York, N.Y.). 288: 522-7. PMID 10775112 DOI: 10.1126/science.288.5465.522  1
2000 Pierre P, Shachar I, Matza D, Gatti E, Flavell RA, Mellman I. Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cells. The Journal of Experimental Medicine. 191: 1057-62. PMID 10727467 DOI: 10.1084/jem.191.6.1057  1
2000 Inaba K, Turley S, Iyoda T, Yamaide F, Shimoyama S, Reis e Sousa C, Germain RN, Mellman I, Steinman RM. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. The Journal of Experimental Medicine. 191: 927-36. PMID 10727455 DOI: 10.1084/jem.191.6.927  1
2000 Gatti E, Velleca MA, Biedermann BC, Ma W, Unternaehrer J, Ebersold MW, Medzhitov R, Pober JS, Mellman I. Large-scale culture and selective maturation of human Langerhans cells from granulocyte colony-stimulating factor-mobilized CD34+ progenitors. Journal of Immunology (Baltimore, Md. : 1950). 164: 3600-7. PMID 10725716  1
2000 Steinman RM, Turley S, Mellman I, Inaba K. The induction of tolerance by dendritic cells that have captured apoptotic cells. The Journal of Experimental Medicine. 191: 411-6. PMID 10662786 DOI: 10.1084/jem.191.3.411  1
2000 Mellman I, Warren G. The road taken: Past and future foundations of membrane traffic Cell. 100: 99-112. PMID 10647935  1
2000 Mellman I. A new year's letter from the editor Journal of Cell Biology. 148: x-xi.  1
1999 Kroschewski R, Hall A, Mellman I. Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells Nature Cell Biology. 1: 8-13. PMID 10559857  1
1999 Fölsch H, Ohno H, Bonifacino JS, Mellman I. A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells Cell. 99: 189-198. PMID 10535737 DOI: 10.1016/S0092-8674(00)81650-5  1
1999 Winckler B, Mellman I. Neuronal polarity: Controlling the sorting and diffusion of membrane components Neuron. 23: 637-640. PMID 10482229 DOI: 10.1016/S0896-6273(01)80021-0  1
1999 Warren G, Mellman I. Bulk flow redux? Cell. 98: 125-127. PMID 10428023 DOI: 10.1016/S0092-8674(00)81006-5  1
1999 Steinman RM, Inaba K, Turley S, Pierre P, Mellman I. Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. Human Immunology. 60: 562-7. PMID 10426272 DOI: 10.1016/S0198-8859(99)00030-0  1
1999 Ohno H, Tomemori T, Nakatsu F, Okazaki Y, Aguilar RC, Foelsch H, Mellman I, Saito T, Shirasawa T, Bonifacino JS. μ1B, a novel adaptor medium chain expressed in polarized epithelial cells Febs Letters. 449: 215-220. PMID 10338135 DOI: 10.1016/S0014-5793(99)00432-9  1
1999 Lu HT, Yang DD, Wysk M, Gatti E, Mellman I, Davis RJ, Flavell RA. Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice. The Embo Journal. 18: 1845-57. PMID 10202148 DOI: 10.1093/emboj/18.7.1845  1
1999 Sheff DR, Daro EA, Hull M, Mellman I. The receptors recycling pathway contains two distinct populations of early endosomes with different sorting functions Journal of Cell Biology. 145: 123-139. PMID 10189373 DOI: 10.1083/jcb.145.1.123  1
1999 Winckler B, Forscher P, Mellman I. A diffusion barrier maintains distribution of membrane proteins in polarized neurons. Nature. 397: 698-701. PMID 10067893 DOI: 10.1038/17806  1
1999 Cleveland DW, Nelson WJ, Franke W, Reichardt L, Fuchs E, Schekman R, Mellman I, Yamada KM. The Journal of Cell Biology: Letter from the editors Journal of Cell Biology. 144: 805. DOI: 10.1083/jcb.144.5.805  1
1999 Albert ML, Bhardwaj N, Steinman RM, Turley S, Garrett W, Mellman I, Inaba K. Uptake and presentation of phagocytosed antigens by dendritic cells Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 363-378. DOI: 10.1016/S1874-5172(99)80040-6  1
1998 Inaba K, Turley S, Yamaide F, Iyoda T, Mahnke K, Inaba M, Pack M, Subklewe M, Sauter B, Sheff D, Albert M, Bhardwaj N, Mellman I, Steinman RM. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. The Journal of Experimental Medicine. 188: 2163-73. PMID 9841929 DOI: 10.1084/jem.188.11.2163  1
1998 Lazzarino DA, Blier P, Mellman I. The monomeric guanosine triphosphatase rab4 controls an essential step on the pathway of receptor-mediated antigen processing in B cells Journal of Experimental Medicine. 188: 1769-1774. PMID 9815254 DOI: 10.1084/jem.188.10.1769  1
1998 Simons K, Mellman I. Thomas Kreis (1952-98) Nature. 395: 446. PMID 9774097 DOI: 10.1038/26639  1
1998 Lewin DA, Sheff D, Ooi CE, Whitney JA, Yamamoto E, Chicione LM, Webster P, Bonifacino JS, Mellman I. Cloning, expression, and localization of a novel gamma-adaptin-like molecule. Febs Letters. 435: 263-8. PMID 9762922 DOI: 10.1016/S0014-5793(98)01083-7  1
1998 Minskoff SA, Matter K, Mellman I. Cutting edge: FcγRII-B1 regulates the presentation of B cell receptor- bound antigens Journal of Immunology. 161: 2079-2083. PMID 9725196  1
1998 Mellman I, Turley SJ, Steinman RM. Antigen processing for amateurs and professionals. Trends in Cell Biology. 8: 231-7. PMID 9695847 DOI: 10.1016/S0962-8924(98)01276-8  1
1998 Pierre P, Mellman I. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells Cell. 93: 1135-1145. PMID 9657147 DOI: 10.1016/S0092-8674(00)81458-0  1
1998 Pierre P, Mellman I. Exploring the mechanisms of antigen processing by cell fractionation Current Opinion in Immunology. 10: 145-153. PMID 9602302 DOI: 10.1016/S0952-7915(98)80242-2  1
1998 Talmor M, Mirza A, Turley S, Mellman I, Hoffman LA, Steinman RM. Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures. European Journal of Immunology. 28: 811-7. PMID 9541575 DOI: 10.1002/(SICI)1521-4141(199803)28:03<811::AID-IMMU811>3.0.CO;2-S  1
1998 Lewin DA, Mellman I. Sorting out adaptors. Biochimica Et Biophysica Acta. 1401: 129-45. PMID 9531969 DOI: 10.1016/S0167-4889(97)00130-4  1
1998 Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C. Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. The Journal of Cell Biology. 140: 1039-53. PMID 9490718 DOI: 10.1083/jcb.140.5.1039  1
1997 Daro E, Sheff D, Gomez M, Kreis T, Mellman I. Inhibition of endosome function in CHO cells bearing a temperature- sensitive defect in the coatomer (COPI) component ε-COP Journal of Cell Biology. 139: 1747-1759. PMID 9412469 DOI: 10.1083/jcb.139.7.1747  1
1997 Sacca R, Turley S, Soong L, Mellman I, Ruddle NH. Transgenic Expression of Lymphotoxin Restores Lymph Nodes to Lymphotoxin-α-Deficient Mice Journal of Immunology. 159: 4252-4260. PMID 9379020  1
1997 Drake JR, Webster P, Gambier JC, Mellman I. Delivery of B cell receptor-internalized antigen to endosomes and class II vesicles Journal of Experimental Medicine. 186: 1299-1306. PMID 9334369 DOI: 10.1084/jem.186.8.1299  1
1997 Ayad N, Hull M, Mellman I. Mitotic phosphorylation of rab4 prevents binding to a specific receptor on endosome membranes Embo Journal. 16: 4497-4507. PMID 9303294 DOI: 10.1093/emboj/16.15.4497  1
1997 Pierre P, Turley SJ, Meltzer J, Mirza A, Steinman R, Mellman I. Localization and intracellular transport of MHC class II molecules in bone marrow-derived dendritic cells Advances in Experimental Medicine and Biology. 417: 179-182. PMID 9286358  1
1997 Pierre P, Turley SJ, Gatti E, Hull M, Meltzer J, Mirza A, Inaba K, Steinman RM, Mellman I. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature. 388: 787-92. PMID 9285592 DOI: 10.1038/42039  1
1997 Schekman R, Mellman I. Does COPI go both ways? Cell. 90: 197-200. PMID 9244292 DOI: 10.1016/S0092-8674(00)80326-8  1
1997 Brachet V, Raposo G, Amigorena S, Mellman I. Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes Journal of Cell Biology. 137: 51-65. PMID 9105036 DOI: 10.1083/jcb.137.1.51  1
1996 Mellman I. Endocytosis and molecular sorting Annual Review of Cell and Developmental Biology. 12: 575-625. PMID 8970738 DOI: 10.1146/annurev.cellbio.12.1.575  1
1996 Mellman I. Membranes and sorting Current Opinion in Cell Biology. 8: 497-498. PMID 8791461 DOI: 10.1016/S0955-0674(96)80026-3  1
1996 Daro E, van der Sluijs P, Galli T, Mellman I. Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling. Proceedings of the National Academy of Sciences of the United States of America. 93: 9559-64. PMID 8790369 DOI: 10.1073/pnas.93.18.9559  1
1996 Cavenagh MM, Whitney JA, Carroll K, Zhang CJ, Boman AL, Rosenwald AG, Mellman I, Kahn RA. Intracellular distribution of Arf proteins in mammalian cells: Arf6 is uniquely localized to the plasma membrane Journal of Biological Chemistry. 271: 21767-21774. PMID 8702973 DOI: 10.1074/jbc.271.36.21767  1
1996 Sheff D, Lowe M, Kreis TE, Mellman I. Biochemical heterogeneity and phosphorylation of coatomer subunits. The Journal of Biological Chemistry. 271: 7230-6. PMID 8636162 DOI: 10.1074/jbc.271.12.7230  1
1996 Pierre P, Denzin LK, Hammond C, Drake JR, Amigorena S, Cresswell P, Mellman I. HLA-DM is localized to conventional and unconventional MHC class II-Containing endocytic compartments Immunity. 4: 229-239. PMID 8624813 DOI: 10.1016/S1074-7613(00)80431-8  1
1995 Mellman I. Molecular sorting of membrane proteins in polarized and nonpolarized cells Cold Spring Harbor Symposia On Quantitative Biology. 60: 745-752. PMID 8824449  1
1995 Whitney JA, Gomez M, Sheff D, Kreis TE, Mellman I. Cytoplasmic coat proteins involved in endosome function. Cell. 83: 703-13. PMID 8521487 DOI: 10.1016/0092-8674(95)90183-3  1
1995 Amigorena S, Webster P, Drake J, Newcomb J, Cresswell P, Mellman I. Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles Journal of Experimental Medicine. 181: 1729-1741. PMID 7722451  1
1995 D'Ambrosio D, Hippen KL, Minskoff SA, Mellman I, Pani G, Siminovitch KA, Cambier JC. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1 Science. 268: 293-297. PMID 7716523  1
1995 Mellman I. Enigma variations: Protein mediators of membrane fusion Cell. 82: 869-872. PMID 7553845 DOI: 10.1016/0092-8674(95)90018-7  1
1995 Mellman I, Pierre P, Amigorena S. Lonely MHC molecules seeking immunogenic peptides for meaningful relationships Current Opinion in Cell Biology. 7: 564-572. PMID 7495577 DOI: 10.1016/0955-0674(95)80014-X  1
1994 Elliott EA, Drake JR, Amigorena S, Elsemore J, Webster P, Mellman I, Flavell RA. The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules Journal of Experimental Medicine. 179: 681-694. PMID 8294875  1
1994 Fuchs R, Ellinger A, Pavelka M, Mellman I, Klapper H. Rat liver endocytic coated vesicles do not exhibit ATP-dependent acidification in vitro Proceedings of the National Academy of Sciences of the United States of America. 91: 4811-4815. PMID 8197139 DOI: 10.1073/pnas.91.11.4811  1
1994 Amigorena S, Drake JR, Webster P, Mellman I. Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes Nature. 369: 113-120. PMID 8177316 DOI: 10.1038/369113a0  1
1994 Matter K, Yamamoto EM, Mellman I. Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells Journal of Cell Biology. 126: 991-1004. PMID 8051216 DOI: 10.1083/jcb.126.4.991  1
1994 Matter K, Mellman I. Mechamisms of cell polarity: sorting and transport in epithelial cells Current Opinion in Cell Biology. 6: 545-554. PMID 7986532 DOI: 10.1016/0955-0674(94)90075-2  1
1994 Bacon RA, Cohen CJ, Lewin DA, Mellman I. Dictyostelium discoideum mutants with temperature-sensitive defects in endocytosis Journal of Cell Biology. 127: 387-399. PMID 7929583 DOI: 10.1083/jcb.127.2.387  1
1994 Cohen CJ, Bacon R, Clarke M, Joiner K, Mellman I. Dictyostelium discoideum mutants with conditional defects in phagocytosis Journal of Cell Biology. 126: 955-966. PMID 7519624 DOI: 10.1083/jcb.126.4.955  1
1994 Mellman I. Editorial overview Current Opinion in Cell Biology. 6: 497-498. DOI: 10.1016/0955-0674(94)90067-1  1
1993 Matter K, Whitney JA, Yamamoto EM, Mellman I. Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells Cell. 74: 1053-1064. PMID 8402881 DOI: 10.1016/0092-8674(93)90727-8  1
1993 Mellman I. Endocytosis and the entry of intracellular parasites Infectious Agents and Disease. 2: 186-192. PMID 8173792  1
1993 Mellman I, Yamamoto E, Whitney JA, Kim M, Hunziker W, Matter K. Molecular sorting in polarized and non-polarized cells: common problems, common solutions Journal of Cell Science. Supplement. 17: 1-7. PMID 8144683  1
1992 Miettinen HM, Matter K, Hunziker W, Rose JK, Mellman I. Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization. The Journal of Cell Biology. 116: 875-88. PMID 1734021  1
1992 Hunziker W, Whitney JA, Mellman I. Brefeldin A and the endocytic pathway Possible implications for membrane traffic and sorting Febs Letters. 307: 93-96. PMID 1639200 DOI: 10.1016/0014-5793(92)80908-Y  1
1992 Harter C, Mellman I. Transport of the lysosomal membrane glycoprotein Igp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane Journal of Cell Biology. 117: 311-325. PMID 1560028  1
1992 Mellman I, Simons K. The Golgi complex: In vitro veritas? Cell. 68: 829-840. PMID 1547485 DOI: 10.1016/0092-8674(92)90027-A  1
1992 Amigorena S, Bonnerot C, Drake JR, Choquet D, Hunziker W, Guillet JG, Webster P, Sautes C, Mellman I, Fridman WH. Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes. Science (New York, N.Y.). 256: 1808-12. PMID 1535455  1
1992 van der Sluijs P, Hull M, Webster P, Mâle P, Goud B, Mellman I. The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway Cell. 70: 729-740. PMID 1516131 DOI: 10.1016/0092-8674(92)90307-X  1
1992 Mellman I. The importance of being acid: the role of acidification in intracellular membrane traffic Journal of Experimental Biology. 172: 39-45. PMID 1491231  1
1992 Podbiliewicz B, Mellman I. [20] Reconstitution of endocytosis and recycling using perforated Madin- Darby canine kidney cells Methods in Enzymology. 219: 198-211. PMID 1487993 DOI: 10.1016/0076-6879(92)19022-X  1
1992 Van Der Sluijs P, Hull M, Huber LA, Mâle P, Goud B, Mellman I. Reversible phosphorylation - Dephosphorylation determines the localization of rab4 during the cell cycle Embo Journal. 11: 4379-4389. PMID 1425574  1
1992 Matter K, Hunziker W, Mellman I. Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants Cell. 71: 741-753. PMID 1423629 DOI: 10.1016/0092-8674(92)90551-M  1
1991 Hunziker W, Whitney JA, Mellman I. Selective inhibition of transcytosis by brefeldin A in MDCK cells Cell. 67: 617-627. PMID 1934063  1
1991 Hunziker W, Mellman I. Relationships between sorting in the exocytic and endocytic pathways of MDCK cells Seminars in Cell Biology. 2: 397-410. PMID 1813029  1
1990 Granger BL, Green SA, Gabel CA, Howe CL, Mellman I, Helenius A. Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells. The Journal of Biological Chemistry. 265: 12036-43. PMID 2142158  1
1989 Schmid S, Fuchs R, Kielian M, Helenius A, Mellman I. Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants. The Journal of Cell Biology. 108: 1291-300. PMID 2925786  0.6
1988 Marsh M, Kern H, Harms E, Schmid S, Mellman I, Helenius A. Co-fractionation of BHK-21 cell endosomes and lysosomes by free-flow electrophoresis. Progress in Clinical and Biological Research. 270: 21-33. PMID 3413159  0.6
1988 Copeland CS, Zimmer KP, Wagner KR, Healey GA, Mellman I, Helenius A. Folding, trimerization, and transport are sequential events in the biogenesis of influenza virus hemagglutinin. Cell. 53: 197-209. PMID 3359486 DOI: 10.1016/0092-8674(88)90381-9  1
1988 Mellman I, Fuchs R, Schmid S, Helenius A. The control of intracellular membrane traffic: implications for Ca++ and phosphate transport. Progress in Clinical and Biological Research. 252: 101-8. PMID 3279424  0.6
1988 Howe CL, Granger BL, Hull M, Green SA, Gabel CA, Helenius A, Mellman I. Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 85: 7577-81. PMID 3174652  1
1988 Vaux DJ, Helenius A, Mellman I. Spike--nucleocapsid interaction in Semliki Forest virus reconstructed using network antibodies. Nature. 336: 36-42. PMID 2460771 DOI: 10.1038/336036a0  0.6
1987 Helenius A, Doxsey S, Mellman I. Viruses as tools in drug delivery. Annals of the New York Academy of Sciences. 507: 1-6. PMID 3126693  1
1987 Marsh M, Schmid S, Kern H, Harms E, Male P, Mellman I, Helenius A. Rapid analytical and preparative isolation of functional endosomes by free flow electrophoresis. The Journal of Cell Biology. 104: 875-86. PMID 3031085  0.6
1986 Ukkonen P, Lewis V, Marsh M, Helenius A, Mellman I. Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes. The Journal of Experimental Medicine. 163: 952-71. PMID 3950548  0.6
1986 Marsh M, Griffiths G, Dean GE, Mellman I, Helenius A. Three-dimensional structure of endosomes in BHK-21 cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 2899-903. PMID 3458249  1
1986 Mellman I, Fuchs R, Helenius A. Acidification of the endocytic and exocytic pathways. Annual Review of Biochemistry. 55: 663-700. PMID 2874766 DOI: 10.1146/annurev.bi.55.070186.003311  0.6
1985 Horwich AL, Fenton WA, Firgaira FA, Fox JE, Kolansky D, Mellman IS, Rosenberg LE. Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor. The Journal of Cell Biology. 100: 1515-21. PMID 3988798 DOI: 10.1083/jcb.100.5.1515  1
1985 Helenius A, Kielian M, Wellsteed J, Mellman I, Rudnick G. Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells. The Journal of Biological Chemistry. 260: 5691-7. PMID 3988769  0.6
1985 Lewis V, Green SA, Marsh M, Vihko P, Helenius A, Mellman I. Glycoproteins of the lysosomal membrane. The Journal of Cell Biology. 100: 1839-47. PMID 3922993 DOI: 10.1083/jcb.100.6.1839  1
1985 Horwich AL, Kalousek F, Mellman I, Rosenberg LE. A leader peptide is sufficient to direct mitochondrial import of a chimeric protein. The Embo Journal. 4: 1129-35. PMID 3891325  1
1983 Mellman IS, Plutner H, Steinman RM, Unkeless JC, Cohn ZA. Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis. The Journal of Cell Biology. 96: 887-95. PMID 6833386  1
1983 Steinman RM, Mellman IS, Muller WA, Cohn ZA. Endocytosis and the recycling of plasma membrane. The Journal of Cell Biology. 96: 1-27. PMID 6298247  1
1981 Sennett C, Rosenberg LE, Mellman IS. Transmembrane transport of cobalamin in prokaryotic and eukaryotic cells. Annual Review of Biochemistry. 50: 1053-86. PMID 6267986 DOI: 10.1146/annurev.bi.50.070181.005201  1
1980 Mellman IS, Steinman RM, Unkeless JC, Cohn ZA. Selective iodination and polypeptide composition of pinocytic vesicles. The Journal of Cell Biology. 86: 712-22. PMID 7410475  1
1980 Steinman RM, Nogueira N, Witmer MD, Tydings JD, Mellman IS. Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages. The Journal of Experimental Medicine. 152: 1248-61. PMID 6448907  1
1979 Youngdahl-Turner P, Mellman IS, Allen RH, Rosenberg LE. Protein mediated vitamin uptake. Adsorptive endocytosis of the transcobalamin II-cobalamin complex by cultured human fibroblasts. Experimental Cell Research. 118: 127-34. PMID 759210 DOI: 10.1016/0014-4827(79)90590-1  1
1979 Mellman I, Willard HF, Youngdahl-Turner P, Rosenberg LE. Cobalamin coenzyme synthesis in normal and mutant human fibroblasts. Evidence for a processing enzyme activity deficient in cblC cells. The Journal of Biological Chemistry. 254: 11847-53. PMID 500677  1
1979 Mellman IS, Lin PF, Ruddle FH, Rosenberg LE. Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1. Proceedings of the National Academy of Sciences of the United States of America. 76: 405-9. PMID 284356  1
1978 Mellman I, Willard HF, Rosenberg LE. Cobalamin binding and cobalamin-dependent enzyme activity in normal and mutant human fibroblasts. The Journal of Clinical Investigation. 62: 952-60. PMID 30783 DOI: 10.1172/JCI109224  0.76
1978 Willard HF, Mellman IS, Rosenberg LE. Genetic complementation among inherited deficiencies of methylmalonyl-CoA mutase activity: evidence for a new class of human cobalamin mutant. American Journal of Human Genetics. 30: 1-13. PMID 23678  0.76
1977 Mellman IS, Youngdahl-Turner P, Willard HF, Rosenberg LE. Intracellular binding of radioactive hydroxocobalamin to cobalamin-dependent apoenzymes in rat liver. Proceedings of the National Academy of Sciences of the United States of America. 74: 916-20. PMID 15258  0.76
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