Tsuyoshi Uehara - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Han W, Ma X, Balibar CJ, Baxter Rath CM, Benton B, Bermingham A, Casey F, Chie-Leon B, Cho MK, Frank AO, Frommlet A, Ho CM, Lee PS, Li M, Lingel A, ... ... Uehara T, et al. Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Journal of the American Chemical Society. PMID 32064871 DOI: 10.1021/Jacs.9B13530  0.327
2019 Hamrick JC, Docquier JD, Uehara T, Myers CL, Six DA, Chatwin CL, John KJ, Vernacchio SF, Cusick SM, Trout REL, Pozzi C, De Luca F, Benvenuti M, Mangani S, Liu B, et al. VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- and metallo-β-lactamases, restores activity of cefepime in and . Antimicrobial Agents and Chemotherapy. PMID 31871094 DOI: 10.1128/Aac.01963-19  0.334
2019 Ma X, Prathapam R, Wartchow C, Chie Leon B, Ho CM, de Vicente J, Han W, Li M, Lu Y, Ramurthy S, Shia S, Steffek M, Uehara T. Structural and biological basis of small molecule inhibition of Escherichia coli LpxD acyltransferase essential for lipopolysaccharide biosynthesis. Acs Infectious Diseases. PMID 31402665 DOI: 10.1021/Acsinfecdis.9B00127  0.381
2019 Sawyer WS, Wang L, Uehara T, Tamrakar P, Prathapam R, Mostafavi M, Metzger LE, Feng B, Baxter Rath CM. Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry. Plos One. 14: e0211803. PMID 30735516 DOI: 10.1371/Journal.Pone.0211803  0.361
2018 Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG. A pathway-directed screen for inhibitors of the bacterial cell elongation machinery. Antimicrobial Agents and Chemotherapy. PMID 30323039 DOI: 10.1128/Aac.01530-18  0.658
2018 Kreamer NNK, Chopra R, Caughlan RE, Fabbro D, Fang E, Gee P, Hunt I, Li M, Leon BC, Muller L, Vash B, Woods AL, Stams T, Dean CR, Uehara T. Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase. Scientific Reports. 8: 14124. PMID 30237436 DOI: 10.1038/S41598-018-32379-1  0.388
2018 Dean CR, Barkan DT, Bermingham A, Blais J, Casey F, Casarez A, Colvin R, Fuller J, Jones AK, Li C, Lopez S, Metzger LE, Mostafavi M, Prathapam R, Rasper D, ... ... Uehara T, et al. The monobactam LYS228: mode of action and mechanisms decreasing susceptibility of and . Antimicrobial Agents and Chemotherapy. PMID 30061293 DOI: 10.1128/Aac.01200-18  0.341
2017 Nilsson I, Grove K, Dovala D, Uehara T, Lapointe G, Six DA. Molecular characterization and verification of azido 3,8-dideoxy-D-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide. The Journal of Biological Chemistry. PMID 29018092 DOI: 10.1074/Jbc.M117.814962  0.343
2016 Meeske AJ, Riley EP, Robins WP, Uehara T, Mekalanos JJ, Kahne D, Walker S, Kruse AC, Bernhardt TG, Rudner DZ. SEDS proteins are a widespread family of bacterial cell wall polymerases. Nature. PMID 27525505 DOI: 10.1038/Nature19331  0.666
2016 Markovski M, Bohrhunter JL, Lupoli TJ, Uehara T, Walker S, Kahne DE, Bernhardt TG. Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071112 DOI: 10.1073/Pnas.1524538113  0.664
2014 Cho H, Uehara T, Bernhardt TG. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. 159: 1300-11. PMID 25480295 DOI: 10.1016/J.Cell.2014.11.017  0.686
2013 Uehara T. [Cell wall shaping during bacterial morphogenesis]. Seikagaku. the Journal of Japanese Biochemical Society. 85: 349-53. PMID 23819393  0.328
2013 Peters NT, Morlot C, Yang DC, Uehara T, Vernet T, Bernhardt TG. Structure-function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site. Molecular Microbiology. 89: 690-701. PMID 23796240 DOI: 10.1111/Mmi.12304  0.691
2012 Liu M, Haenssler E, Uehara T, Losick VP, Park JT, Isberg RR. The Legionella pneumophila EnhC protein interferes with immunostimulatory muramyl peptide production to evade innate immunity. Cell Host & Microbe. 12: 166-76. PMID 22901537 DOI: 10.1016/J.Chom.2012.06.004  0.627
2011 Uehara T, Bernhardt TG. More than just lysins: peptidoglycan hydrolases tailor the cell wall. Current Opinion in Microbiology. 14: 698-703. PMID 22055466 DOI: 10.1016/J.Mib.2011.10.003  0.672
2011 Yang DC, Peters NT, Parzych KR, Uehara T, Markovski M, Bernhardt TG. An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring. Proceedings of the National Academy of Sciences of the United States of America. 108: E1052-60. PMID 22006326 DOI: 10.1073/Pnas.1107780108  0.663
2010 Paradis-Bleau C, Markovski M, Uehara T, Lupoli TJ, Walker S, Kahne DE, Bernhardt TG. Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases. Cell. 143: 1110-20. PMID 21183074 DOI: 10.1016/J.Cell.2010.11.037  0.688
2010 Uehara T, Parzych KR, Dinh T, Bernhardt TG. Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis. The Embo Journal. 29: 1412-22. PMID 20300061 DOI: 10.1038/Emboj.2010.36  0.697
2010 Morlot C, Uehara T, Marquis KA, Bernhardt TG, Rudner DZ. A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis. Genes & Development. 24: 411-22. PMID 20159959 DOI: 10.1101/Gad.1878110  0.696
2009 Uehara T, Dinh T, Bernhardt TG. LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli. Journal of Bacteriology. 191: 5094-107. PMID 19525345 DOI: 10.1128/Jb.00505-09  0.687
2008 Uehara T, Park JT. Peptidoglycan Recycling. Ecosal Plus. 3. PMID 26443726 DOI: 10.1128/ecosalplus.4.7.1.5  0.667
2008 Park JT, Uehara T. How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Microbiology and Molecular Biology Reviews : Mmbr. 72: 211-27, table of con. PMID 18535144 DOI: 10.1128/Mmbr.00027-07  0.696
2008 Uehara T, Park JT. Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. Journal of Bacteriology. 190: 3914-22. PMID 18390656 DOI: 10.1128/Jb.00207-08  0.662
2007 Uehara T, Park JT. An anhydro-N-acetylmuramyl-L-alanine amidase with broad specificity tethered to the outer membrane of Escherichia coli. Journal of Bacteriology. 189: 5634-41. PMID 17526703 DOI: 10.1128/Jb.00446-07  0.642
2006 Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT. MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall. Journal of Bacteriology. 188: 1660-2. PMID 16452451 DOI: 10.1128/Jb.188.4.1660-1662.2006  0.644
2005 Uehara T, Suefuji K, Valbuena N, Meehan B, Donegan M, Park JT. Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate Journal of Bacteriology. 187: 3643-3649. PMID 15901686 DOI: 10.1128/Jb.187.11.3643-3649.2005  0.655
2004 Uehara T, Park JT. The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling. Journal of Bacteriology. 186: 7273-9. PMID 15489439 DOI: 10.1128/Jb.186.21.7273-7279.2004  0.665
2003 Uehara T, Park JT. Identification of MpaA, an amidase in Escherichia coli that hydrolyzes the gamma-D-glutamyl-meso-diaminopimelate bond in murein peptides. Journal of Bacteriology. 185: 679-82. PMID 12511517 DOI: 10.1128/Jb.185.2.679-682.2003  0.645
2002 Uehara T, Park JT. Role of the murein precursor UDP-N-acetylmuramyl-L-Ala-gamma-D-Glu-meso-diaminopimelic acid-D-Ala-D-Ala in repression of beta-lactamase induction in cell division mutants. Journal of Bacteriology. 184: 4233-9. PMID 12107141 DOI: 10.1128/Jb.184.15.4233-4239.2002  0.655
2001 Uehara T, Matsuzawa H, Nishimura A. HscA is involved in the dynamics of FtsZ-ring formation in Escherichia coli K12. Genes to Cells. 6: 803-814. PMID 11554926 DOI: 10.1046/J.1365-2443.2001.00463.X  0.369
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