Lenno Krenning, Ph.D. - Publications

Affiliations: 
2010-2015 Cell Biology Netherlands Cancer Institute 
 2016-2018 Gene Expression Hubrecht Institute 
 2018- Cell Biology Netherlands Cancer Institute 
Area:
Cell Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Koob L, Friskes A, van Bergen L, Feringa FM, van den Broek B, Koeleman ES, van Beek E, Schubert M, Blomen VA, Brummelkamp TR, Krenning L, Medema RH. MND1 enables homologous recombination in somatic cells primarily outside the context of replication. Molecular Oncology. PMID 37195379 DOI: 10.1002/1878-0261.13448  0.702
2022 Friskes A, Koob L, Krenning L, Severson TM, Koeleman ES, Vergara X, Schubert M, van den Berg J, Evers B, Manjón AG, Joosten S, Kim Y, Zwart W, Medema RH. Double-strand break toxicity is chromatin context independent. Nucleic Acids Research. 50: 9930-9947. PMID 36107780 DOI: 10.1093/nar/gkac758  0.701
2022 Pogacar Z, Johnson JL, Krenning L, De Conti G, Jochems F, Lieftink C, Velds A, Wardak L, Groot K, Schepers A, Wang L, Song JY, van de Ven M, van Tellingen O, Medema RH, et al. Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity. Plos One. 17: e0273182. PMID 36067171 DOI: 10.1371/journal.pone.0273182  0.666
2022 Krenning L, Sonneveld S, Tanenbaum M. Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during the mitosis-to-G1 phase transition. Elife. 11. PMID 35103592 DOI: 10.7554/eLife.71356  0.75
2021 Shaltiel IA, Llopis A, Aprelia M, Klompmaker R, Menegakis A, Krenning L, Medema RH. Combined Inactivation of Pocket Proteins and APC/C by Cdk4/6 Controls Recovery from DNA Damage in G1 Phase. Cells. 10. PMID 33806417 DOI: 10.3390/cells10030550  0.719
2021 Menegakis A, Klompmaker R, Vennin C, Arbusà A, Damen M, van den Broek B, Zips D, van Rheenen J, Krenning L, Medema RH. Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence. Cells. 10. PMID 33801903 DOI: 10.3390/cells10030610  0.672
2021 García-Santisteban I, Llopis A, Krenning L, Vallejo-Rodríguez J, van den Broek B, Zubiaga AM, Medema RH. Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells. Bmc Biology. 19: 35. PMID 33607997 DOI: 10.1186/s12915-021-00965-x  0.72
2021 Hornsveld M, Feringa FM, Krenning L, van den Berg J, Smits LMM, Nguyen NBT, Rodríguez-Colman MJ, Dansen TB, Medema RH, Burgering BMT. A FOXO-dependent replication checkpoint restricts proliferation of damaged cells. Cell Reports. 34: 108675. PMID 33503422 DOI: 10.1016/j.celrep.2020.108675  0.703
2021 Krenning L, Raaijmakers JA, Medema RH. Centrosomes: Please keep your social distance! The Embo Journal. e107525. PMID 33491191 DOI: 10.15252/embj.2020107525  0.641
2020 Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 79: 191-198.e3. PMID 32619469 DOI: 10.1016/J.Molcel.2020.06.008  0.752
2020 Battich N, Beumer J, de Barbanson B, Krenning L, Baron CS, Tanenbaum ME, Clevers H, van Oudenaarden A. Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies. Science (New York, N.Y.). 367: 1151-1156. PMID 32139547 DOI: 10.1126/Science.Aax3072  0.743
2019 Krenning L, van den Berg J, Medema RH. Life or Death after a Break: What Determines the Choice? Molecular Cell. PMID 31561953 DOI: 10.1016/J.Molcel.2019.08.023  0.717
2018 Feringa FM, Raaijmakers JA, Hadders MA, Vaarting C, Macurek L, Heitink L, Krenning L, Medema RH. Persistent repair intermediates induce senescence. Nature Communications. 9: 3923. PMID 30254262 DOI: 10.1038/S41467-018-06308-9  0.76
2018 Soto M, García-Santisteban I, Krenning L, Medema RH, Raaijmakers JA. Chromosomes trapped in micronuclei are liable to segregation errors. Journal of Cell Science. PMID 29930083 DOI: 10.1242/Jcs.214742  0.693
2017 Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 68: 210-223.e6. PMID 28985505 DOI: 10.1016/J.Molcel.2017.09.012  0.716
2016 Feringa FM, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, Medema RH. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nature Communications. 7: 12618. PMID 27561326 DOI: 10.1038/Ncomms12618  0.762
2015 Shaltiel IA, Krenning L, Bruinsma W, Medema RH. The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle. Journal of Cell Science. 128: 607-20. PMID 25609713 DOI: 10.1242/Jcs.163766  0.764
2014 Krenning L, Medema RH. Enter the nucleus to exit the cycle. Cell Cycle (Georgetown, Tex.). 13: 2651-2. PMID 25486348 DOI: 10.4161/15384101.2014.948783  0.648
2014 Krenning L, Feringa FM, Shaltiel IA, van den Berg J, Medema RH. Transient activation of p53 in G2 phase is sufficient to induce senescence. Molecular Cell. 55: 59-72. PMID 24910099 DOI: 10.1016/J.Molcel.2014.05.007  0.734
2012 Espeut J, Cheerambathur DK, Krenning L, Oegema K, Desai A. Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. The Journal of Cell Biology. 196: 469-82. PMID 22331849 DOI: 10.1083/Jcb.201111107  0.441
2010 Alvarez-Fernández M, Halim VA, Krenning L, Aprelia M, Mohammed S, Heck AJ, Medema RH. Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1. Embo Reports. 11: 452-8. PMID 20379221 DOI: 10.1038/Embor.2010.46  0.747
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