| Year |
Citation |
Score |
| 2024 |
Chen Y, Chen M, Liu Y, Li Q, Xue Y, Liu L, Liang R, Xiong Y, Zhao J, Chen J, Lin W, Wang J, Pan Y, Stohl W, Zheng SG. BAFF promotes follicular helper T cell development and germinal center formation through BR3 signal. Jci Insight. PMID 39325665 DOI: 10.1172/jci.insight.183400 |
0.33 |
|
| 2023 |
Chen Y, Liang R, Shi X, Shen R, Liu L, Liu Y, Xue Y, Guo X, Dang J, Zeng D, Huang F, Sun J, Zhang J, Wang J, Olsen N, ... ... Zheng SG, et al. Targeting kinase ITK treats autoimmune arthritis via orchestrating T cell differentiation and function. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 169: 115886. PMID 37992572 DOI: 10.1016/j.biopha.2023.115886 |
0.361 |
|
| 2022 |
Chen W, Huang W, Xue Y, Chen Y, Qian W, Ma J, August A, Wang J, Zheng SG, Lin J. Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3 Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation. Frontiers in Immunology. 13: 900139. PMID 35603221 DOI: 10.3389/fimmu.2022.900139 |
0.421 |
|
| 2021 |
Kim MC, Borcherding N, Ahmed KK, Voigt AP, Vishwakarma A, Kolb R, Kluz PN, Pandey G, De U, Drashansky T, Helm EY, Zhang X, Gibson-Corley KN, Klesney-Tait J, Zhu Y, ... ... Zheng SG, et al. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nature Communications. 12: 5764. PMID 34599187 DOI: 10.1038/s41467-021-26091-4 |
0.359 |
|
| 2021 |
Chen J, Huang F, Hou Y, Lin X, Liang R, Hu X, Zhao J, Wang J, Olsen N, Zheng SG. TGF-β-induced CD4+ FoxP3+ regulatory T cell-derived extracellular vesicles modulate Notch1 signaling through miR-449a and prevent collagen-induced arthritis in a murine model. Cellular & Molecular Immunology. PMID 34556822 DOI: 10.1038/s41423-021-00764-y |
0.338 |
|
| 2020 |
Liu X, Zhao J, Shi C, Liu Z, Shen H, Dang J, Li Y, Yang D, Wei J, Kang L, Zhou J, Cao F, Zheng SG, Wang Z. Construction of CII-Specific CAR-T to Explore the Cytokine Cascades Between Cartilage-Reactive T Cells and Chondrocytes. Frontiers in Immunology. 11: 568741. PMID 33343563 DOI: 10.3389/fimmu.2020.568741 |
0.323 |
|
| 2020 |
Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG. Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Ileitis Depending on IL-22 Expression. Frontiers in Immunology. 11: 592865. PMID 33193440 DOI: 10.3389/fimmu.2020.592865 |
0.487 |
|
| 2020 |
Liu Y, Qi G, Bellanti JA, Moser R, Ryffel B, Zheng SG. Regulatory T cells: A potential weapon to combat COVID-19? Medcomm. PMID 32838397 DOI: 10.1002/Mco2.12 |
0.466 |
|
| 2020 |
Chen Y, Xu Z, Liang R, Wang J, Xu A, Na N, Li B, Wang R, Joseph M, Olsen N, Hsueh W, Zheng SG. CD4CD126 Foxp3 Cell Population Represents a Superior Subset of Regulatory T Cells in Treating Autoimmune Diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32738192 DOI: 10.1016/j.ymthe.2020.07.020 |
0.42 |
|
| 2020 |
Liu Y, Qi G, Wang J, Huang F, Bellanti JA, Zheng SG. CD4CD25CD226: An innovative approach to identify human regulatory T cells. The Journal of Allergy and Clinical Immunology. PMID 32668282 DOI: 10.1016/J.Jaci.2020.06.029 |
0.386 |
|
| 2020 |
Yang J, Wei P, Barbi J, Huang Q, Yang E, Bai Y, Nie J, Gao Y, Tao J, Lu Y, Xie C, Hou X, Ren J, Wu X, Meng J, ... ... Zheng SG, et al. The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation. Embo Reports. e50308. PMID 32644293 DOI: 10.15252/Embr.202050308 |
0.441 |
|
| 2020 |
Huang W, Solouki S, Koylass N, Zheng SG, August A. Author Correction: ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells. Nature Communications. 11: 2579. PMID 32427893 DOI: 10.1038/S41467-020-16420-4 |
0.316 |
|
| 2020 |
Liu Y, Jarjour W, Olsen N, Zheng SG. Traitor or warrior-Treg cells sneaking into the lesions of psoriatic arthritis. Clinical Immunology (Orlando, Fla.). 108425. PMID 32305454 DOI: 10.1016/j.clim.2020.108425 |
0.341 |
|
| 2020 |
Zhang X, Olsen N, Zheng SG. The progress and prospect of regulatory T cells in autoimmune diseases. Journal of Autoimmunity. 102461. PMID 32305296 DOI: 10.1016/j.jaut.2020.102461 |
0.354 |
|
| 2020 |
Zhao J, Chen J, Huang F, Wang J, Su W, Zhou J, Qi Q, Cao F, Sun B, Liu Z, Bellanti JA, Zheng SG. Erratum: Human gingiva tissue-derived MSC ameliorates immune-mediated bone marrow failure of aplastic anemia suppression of Th1 and Th17 cells and enhancement of CD4+Foxp3+ regulatory T cells differentiation. American Journal of Translational Research. 12: 1167. PMID 32269743 |
0.325 |
|
| 2020 |
Jiang X, Chen Y, Liu D, Shi T, Cheng X, He W, Li Y, Ryffel B, Zheng SG, Zheng Y. Secoeudesma sesquiterpenes lactone A alleviates inflammation and offers adjuvant protection in severe infection of carbapenem-resistant Klebsiella pneumoniae. Journal of Ethnopharmacology. 112605. PMID 31981749 DOI: 10.1016/J.Jep.2020.112605 |
0.392 |
|
| 2020 |
Chang L, Wang Z, Li S, Chen X, Li X, Zhao J, Lai X, Huang J, Wu X, Huang Z, Bellanti JA, Zheng SG, Zhang G. Type 2 inflammation suppression by T regulatory cells attenuates the eosinophil recruitment in mucosa of chronic sinusitis. Clinical Science (London, England : 1979). PMID 31922185 DOI: 10.1042/CS20190388 |
0.413 |
|
| 2019 |
Li X, Wang Z, Chang L, Chen X, Yang L, Lai X, Li S, Huang J, Huang Z, Wu X, Bellanti JA, Zheng SG, Zhang G. γδT Cells Contribute to Type 2 Inflammatory Profiles in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps. Clinical Science (London, England : 1979). PMID 31722010 DOI: 10.1042/CS20190481 |
0.31 |
|
| 2019 |
Huang Z, Xie L, Li H, Liu X, Bellanti JA, Zheng SG, Su W. Insight into interleukin-37: The potential therapeutic target in allergic diseases. Cytokine & Growth Factor Reviews. PMID 31672283 DOI: 10.1016/j.cytogfr.2019.10.003 |
0.323 |
|
| 2019 |
Li H, Deng Y, Liang J, Huang F, Qiu W, Zhang M, Long Y, Hu X, Lu Z, Liu W, Zheng SG. Mesenchymal stromal cells attenuate multiple sclerosis IDO-dependent increasing the suppressive proportion of CD5+ IL-10+ B cells. American Journal of Translational Research. 11: 5673-5688. PMID 31632539 |
0.361 |
|
| 2019 |
Su W, Chen X, Zhu W, Yu J, Li W, Li Y, Li Z, Olsen N, Liang D, Zheng SG. The cAMP-Adenosine Feedback Loop Maintains the Suppressive Function of Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 31420466 DOI: 10.4049/jimmunol.1801306 |
0.374 |
|
| 2019 |
Lai X, Li X, Chang L, Chen X, Huang Z, Bao H, Huang J, Yang L, Wu X, Wang Z, Bellanti JA, Zheng SG, Zhang G. IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis STAT3 Pathway. Frontiers in Immunology. 10: 1682. PMID 31379870 DOI: 10.3389/fimmu.2019.01682 |
0.314 |
|
| 2019 |
Chen Y, Wang J, Wang X, Li X, Song J, Fang J, Liu X, Liu T, Wang D, Li Q, Wen S, Ma D, Xia J, Luo L, Zheng SG, et al. Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T cell Immunity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31350312 DOI: 10.1158/1078-0432.Ccr-18-4134 |
0.309 |
|
| 2019 |
Liu X, Xiao Y, Pan Y, Li H, Zheng SG, Su W. The role of the IL-33/ST2 axis in autoimmune disorders: Friend or foe? Cytokine & Growth Factor Reviews. PMID 31085085 DOI: 10.1016/j.cytogfr.2019.04.004 |
0.415 |
|
| 2019 |
Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG. Blockade of IL-33R/ST2 Signaling Attenuates Ileitis Depending on IL-22 Expression. Frontiers in Immunology. 10: 702. PMID 31057534 DOI: 10.3389/Fimmu.2019.00702 |
0.517 |
|
| 2019 |
Yang M, Liu Y, Mo B, Xue Y, Ye C, Jiang Y, Bi X, Liu M, Wu Y, Wang J, Olsen N, Pan Y, Zheng SG. Helios but not CD226, TIGIT and Foxp3 is a Potential Marker for CD4 Treg Cells in Patients with Rheumatoid Arthritis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 1178-1192. PMID 30990587 DOI: 10.33594/000000080 |
0.315 |
|
| 2019 |
Deng YN, Bellanti JA, Zheng SG. Essential Kinases and Transcriptional Regulators and Their Roles in Autoimmunity. Biomolecules. 9. PMID 30974919 DOI: 10.3390/biom9040145 |
0.302 |
|
| 2019 |
Zhou L, Wang J, Li J, Li T, Chen Y, June RR, Zheng SG. 1,25-Dihydroxyvitamin D3 Ameliorates Collagen-Induced Arthritis via Suppression of Th17 Cells Through miR-124 Mediated Inhibition of IL-6 Signaling. Frontiers in Immunology. 10: 178. PMID 30792721 DOI: 10.3389/Fimmu.2019.00178 |
0.527 |
|
| 2019 |
Luo Y, Xue Y, Wang J, Dang J, Fang Q, Huang G, Olsen N, Zheng SG. Negligible Effect of Sodium Chloride on the Development and Function of TGF-β-Induced CD4 Foxp3 Regulatory T Cells. Cell Reports. 26: 1869-1879.e3. PMID 30759396 DOI: 10.1016/J.Celrep.2019.01.066 |
0.438 |
|
| 2019 |
Yang S, Xie C, Chen Y, Wang J, Chen X, Lu Z, June RR, Zheng SG. Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4Foxp3 induced Treg cells in vitro and in vivo periphery in autoimmune diseases. Cell Death & Disease. 10: 27. PMID 30631042 DOI: 10.1038/S41419-018-1266-6 |
0.468 |
|
| 2018 |
Mao YM, Zhao CN, Leng J, Leng RX, Ye DQ, Zheng SG, Pan HF. Interleukin-13: A promising therapeutic target for autoimmune disease. Cytokine & Growth Factor Reviews. PMID 30581068 DOI: 10.1016/J.Cytogfr.2018.12.001 |
0.472 |
|
| 2018 |
Liu F, Feng XX, Zhu SL, Huang HY, Chen YD, Pan YF, June RR, Zheng SG, Huang JL. Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis MAPK/ERK Signaling Pathway. Frontiers in Immunology. 9: 2847. PMID 30568656 DOI: 10.3389/Fimmu.2018.02847 |
0.33 |
|
| 2018 |
Huang W, Solouki S, Carter C, Zheng SG, August A. Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages. Frontiers in Immunology. 9: 2625. PMID 30510554 DOI: 10.3389/Fimmu.2018.02625 |
0.539 |
|
| 2018 |
Chen X, Chang L, Li X, Huang J, Yang L, Lai X, Huang Z, Wang Z, Wu X, Zhao J, Bellanti JA, Zheng SG, Zhang G. Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis. Frontiers in Immunology. 9: 2121. PMID 30283454 DOI: 10.3389/Fimmu.2018.02121 |
0.42 |
|
| 2018 |
Huang Z, Liu Y, Qi G, Brand D, Zheng SG. Role of Vitamin A in the Immune System. Journal of Clinical Medicine. 7. PMID 30200565 DOI: 10.3390/Jcm7090258 |
0.313 |
|
| 2018 |
Chen M, Lin X, Cheukfai Li, Olsen N, He X, Zheng SG. Advances in T follicular helper and T follicular regulatory cells in transplantation immunity. Transplantation Reviews (Orlando, Fla.). PMID 30139705 DOI: 10.1016/J.Trre.2018.07.002 |
0.393 |
|
| 2018 |
Chen W, Wang J, Xu Z, Huang F, Qian W, Ma J, Wee HB, Lewis GS, June RR, Schafer PH, Lin J, Zheng SG. Apremilast Ameliorates Experimental Arthritis Suppression of Th1 and Th17 Cells and Enhancement of CD4Foxp3 Regulatory T Cells Differentiation. Frontiers in Immunology. 9: 1662. PMID 30072998 DOI: 10.3389/Fimmu.2018.01662 |
0.399 |
|
| 2018 |
Zou F, Wang X, Han X, Rothschild G, Zheng SG, Basu U, Sun J. Expression and Function of Tetraspanins and Their Interacting Partners in B Cells. Frontiers in Immunology. 9: 1606. PMID 30072987 DOI: 10.3389/Fimmu.2018.01606 |
0.376 |
|
| 2018 |
Zhang X, Huang F, Li W, Dang JL, Yuan J, Wang J, Zeng DL, Sun CX, Liu YY, Ao Q, Tan H, Su W, Qian X, Olsen N, Zheng SG. Human Gingiva-Derived Mesenchymal Stem Cells Modulate Monocytes/Macrophages and Alleviate Atherosclerosis. Frontiers in Immunology. 9: 878. PMID 29760701 DOI: 10.3389/Fimmu.2018.00878 |
0.337 |
|
| 2018 |
Yang S, Wang J, Brand DD, Zheng SG. Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications. Frontiers in Immunology. 9: 784. PMID 29725328 DOI: 10.3389/Fimmu.2018.00784 |
0.392 |
|
| 2018 |
Mo BY, Guo XH, Yang MR, Liu F, Bi X, Liu Y, Fang LK, Luo XQ, Wang J, Bellanti JA, Pan YF, Zheng SG. Long Non-Coding RNA GAPLINC Promotes Tumor-Like Biologic Behaviors of Fibroblast-Like Synoviocytes as MicroRNA Sponging in Rheumatoid Arthritis Patients. Frontiers in Immunology. 9: 702. PMID 29692777 DOI: 10.3389/Fimmu.2018.00702 |
0.307 |
|
| 2018 |
Ye C, Brand D, Zheng SG. Targeting IL-2: an unexpected effect in treating immunological diseases. Signal Transduction and Targeted Therapy. 3: 2. PMID 29527328 DOI: 10.1038/S41392-017-0002-5 |
0.487 |
|
| 2018 |
Lawless OJ, Bellanti JA, Brown ML, Sandberg K, Umans JG, Zhou L, Chen W, Wang J, Wang K, Zheng SG.
induction of T regulatory cells by a methylated CpG DNA sequence in humans: Potential therapeutic applications in allergic and autoimmune diseases. Allergy and Asthma Proceedings. 39: 143-152. PMID 29490770 DOI: 10.2500/Aap.2018.39.4113 |
0.451 |
|
| 2018 |
Zhong H, Liu Y, Xu Z, Liang P, Yang H, Zhang X, Zhao J, Chen J, Fu S, Tang Y, Lv J, Wang J, Olsen N, Xu A, Zheng SG. TGF-β-Induced CD8CD103Regulatory T Cells Show Potent Therapeutic Effect on Chronic Graft-versus-Host Disease Lupus by Suppressing B Cells. Frontiers in Immunology. 9: 35. PMID 29441062 DOI: 10.3389/Fimmu.2018.00035 |
0.51 |
|
| 2017 |
Xiao ZX, Zheng X, Hu L, Wang J, Olsen N, Zheng SG. Immunosuppressive Effect of B7-H4 Pathway in a Murine Systemic Lupus Erythematosus Model. Frontiers in Immunology. 8: 1765. PMID 29321778 DOI: 10.3389/Fimmu.2017.01765 |
0.322 |
|
| 2017 |
Zhang W, Zhou L, Dang J, Zhang X, Wang J, Chen Y, Liang J, Li D, Ma J, Yuan J, Chen W, Zadeh HH, Olsen N, Zheng SG. Human Gingiva-Derived Mesenchymal Stem Cells Ameliorate Streptozoticin-induced T1DM in mice via Suppression of T effector cells and Up-regulating Treg Subsets. Scientific Reports. 7: 15249. PMID 29127315 DOI: 10.1038/S41598-017-14979-5 |
0.436 |
|
| 2017 |
Liao T, Xue Y, Zhao D, Li S, Liu M, Chen J, Brand DD, Zheng H, Zhang Y, Zheng SG, Sun Q. In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-β-Induced CD4(+)Foxp3(+) Regulatory T Cells. Frontiers in Immunology. 8: 1334. PMID 29085374 DOI: 10.3389/Fimmu.2017.01334 |
0.435 |
|
| 2017 |
Chen W, Xu Z, Zheng Y, Wang J, Qian W, Olsen N, Brand D, Lin J, Zheng SG. A protocol to develop T helper and Treg cells in vivo. Cellular & Molecular Immunology. PMID 29082917 DOI: 10.1038/Cmi.2017.116 |
0.497 |
|
| 2017 |
Lei F, Haque M, Sandhu P, Ravi S, Song J, Ni B, Zheng S, Fang D, Jia H, Yang JM, Song J. Development and characterization of naive single-type tumor antigen-specific CD8(+) T lymphocytes from murine pluripotent stem cells. Oncoimmunology. 6: e1334027. PMID 28811978 DOI: 10.1080/2162402X.2017.1334027 |
0.388 |
|
| 2017 |
Chen X, Su W, Wan T, Yu J, Zhu W, Tang F, Liu G, Olsen N, Liang D, Zheng SG. Sodium Butyrate Regulates Th17/Treg Cell Balance to Ameliorate Uveitis via the Nrf2/HO-1 Pathway. Biochemical Pharmacology. PMID 28684304 DOI: 10.1016/J.Bcp.2017.06.136 |
0.488 |
|
| 2017 |
Su W, Li Z, Jia Y, Zhu Y, Cai W, Wan P, Zhang Y, Zheng SG, Zhuo Y. microRNA-21a-5p/PDCD4 axis regulates mesenchymal stem cell-induced neuroprotection in acute glaucoma. Journal of Molecular Cell Biology. PMID 28655163 DOI: 10.1093/Jmcb/Mjx022 |
0.339 |
|
| 2017 |
Huang W, Solouki S, Koylass N, Zheng SG, August A. ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells. Nature Communications. 8: 15871. PMID 28635957 DOI: 10.1038/Ncomms15871 |
0.47 |
|
| 2017 |
Guan SY, Leng RX, Tao JH, Li XP, Ye DQ, Olsen N, Zheng SG, Pan HF. Hypoxia-inducible factor-1α: a promising therapeutic target for autoimmune diseases. Expert Opinion On Therapeutic Targets. PMID 28553732 DOI: 10.1080/14728222.2017.1336539 |
0.322 |
|
| 2017 |
Haque R, Song J, Haque M, Lei F, Sandhu P, Ni B, Zheng S, Fang D, Yang JM, Song J. c-Myc-Induced Survivin Is Essential for Promoting the Notch-Dependent T Cell Differentiation from Hematopoietic Stem Cells. Genes. 8. PMID 28272325 DOI: 10.3390/Genes8030097 |
0.395 |
|
| 2017 |
Peng WX, Zhu SL, Zhang BY, Shi YM, Feng XX, Liu F, Huang JL, Zheng SG. Smoothened Regulates Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Activation of Rho GTPase Signaling. Frontiers in Immunology. 8: 159. PMID 28261216 DOI: 10.3389/Fimmu.2017.00159 |
0.318 |
|
| 2017 |
Huang F, Chen M, Chen W, Gu J, Yuan J, Xue Y, Dang J, Su W, Wang J, Zadeh HH, He X, Rong L, Olsen N, Zheng SG. Human Gingiva-Derived Mesenchymal Stem Cells Inhibit Xeno-Graft-versus-Host Disease via CD39-CD73-Adenosine and IDO Signals. Frontiers in Immunology. 8: 68. PMID 28210258 DOI: 10.3389/Fimmu.2017.00068 |
0.453 |
|
| 2017 |
Liu Y, Pan YF, Xue YQ, Fang LK, Guo XH, Guo X, Liu M, Mo BY, Yang MR, Liu F, Wu YT, Olsen N, Zheng SG. uPAR promotes tumor-like biologic behaviors of fibroblast-like synoviocytes through PI3K/Akt signaling pathway in patients with rheumatoid arthritis. Cellular & Molecular Immunology. PMID 28090093 DOI: 10.1038/Cmi.2016.60 |
0.339 |
|
| 2017 |
Chen M, Lin X, Wang J, Olsen N, Zheng SG. Advances in the role of follicular T helper cells in graft versus host diseases Liver Research. 1: 131-134. DOI: 10.1016/J.Livres.2017.06.001 |
0.489 |
|
| 2016 |
Luo Y, Zheng SG. Hall of Fame among Pro-inflammatory Cytokines: Interleukin-6 Gene and Its Transcriptional Regulation Mechanisms. Frontiers in Immunology. 7: 604. PMID 28066415 DOI: 10.3389/Fimmu.2016.00604 |
0.445 |
|
| 2016 |
Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, Liang R, Zhang Y, Leng Q, Wei G, Shi G, Zhu R, Li D, Wang H, Zheng SG, et al. USP21 prevents the generation of T-helper-1-like Treg cells. Nature Communications. 7: 13559. PMID 27857073 DOI: 10.1038/Ncomms13559 |
0.475 |
|
| 2016 |
Wang K, Gu J, Ni X, Ding Z, Wang Q, Zhou H, Zheng S, Li B, Lu L. CD25 signaling regulates the function and stability of peripheral Foxp3+ regulatory T cells derived from the spleen and lymph nodes of mice. Molecular Immunology. 76: 35-40. PMID 27344615 DOI: 10.1016/J.Molimm.2016.06.007 |
0.467 |
|
| 2016 |
Xu A, Liu Y, Chen W, Wang J, Xue Y, Huang F, Rong L, Lin J, Liu D, Yan M, Li QZ, Li B, Song J, Olsen N, Zheng SG. TGF-β-Induced Regulatory T Cells Directly Suppress B Cell Responses through a Noncytotoxic Mechanism. Journal of Immunology (Baltimore, Md. : 1950). PMID 27001954 DOI: 10.4049/Jimmunol.1501740 |
0.468 |
|
| 2016 |
Haque M, Song J, Fino K, Sandhu P, Song X, Lei F, Zheng S, Ni B, Fang D, Song J. Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity. Scientific Reports. 6: 20588. PMID 26846186 DOI: 10.1038/Srep20588 |
0.418 |
|
| 2015 |
Nie J, Li YY, Zheng SG, Tsun A, Li B. FOXP3(+) Treg Cells and Gender Bias in Autoimmune Diseases. Frontiers in Immunology. 6: 493. PMID 26441996 DOI: 10.3389/Fimmu.2015.00493 |
0.486 |
|
| 2015 |
Li B, Zheng SG. How regulatory T cells sense and adapt to inflammation. Cellular & Molecular Immunology. PMID 26277895 DOI: 10.1038/Cmi.2015.65 |
0.497 |
|
| 2015 |
Zhu SL, Huang JL, Peng WX, Wu DC, Luo MQ, Li QX, Li ZX, Feng XX, Liu F, Wang MX, Chen WQ, Olsen N, Zheng SG. Inhibition of smoothened decreases proliferation of synoviocytes in rheumatoid arthritis. Cellular & Molecular Immunology. PMID 26189371 DOI: 10.1038/Cmi.2015.67 |
0.344 |
|
| 2015 |
Gao Y, Tang J, Chen W, Li Q, Nie J, Lin F, Wu Q, Chen Z, Gao Z, Fan H, Tsun A, Shen J, Chen G, Liu Z, Lou Z, ... ... Zheng SG, et al. Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1. Proceedings of the National Academy of Sciences of the United States of America. 112: E3246-54. PMID 26060310 DOI: 10.1073/Pnas.1421463112 |
0.45 |
|
| 2015 |
Madouri F, Guillou N, Fauconnier L, Marchiol T, Rouxel N, Chenuet P, Ledru A, Apetoh L, Ghiringhelli F, Chamaillard M, Zheng SG, Trovero F, Quesniaux VF, Ryffel B, Togbe D. Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation. Journal of Molecular Cell Biology. 7: 351-65. PMID 25714839 DOI: 10.1093/Jmcb/Mjv012 |
0.759 |
|
| 2015 |
Su W, Wan Q, Huang J, Han L, Chen X, Chen G, Olsen N, Zheng SG, Liang D. Culture medium from TNF-α-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms. The Journal of Allergy and Clinical Immunology. PMID 25652765 DOI: 10.1016/J.Jaci.2014.12.1926 |
0.356 |
|
| 2015 |
Liu ZM, Wang KP, Ma J, Zheng SG. The role of all- trans retinoic acid in the biology of Foxp3 + regulatory T cells Cellular & Molecular Immunology. 12: 553-557. PMID 25640656 DOI: 10.1038/Cmi.2014.133 |
0.487 |
|
| 2015 |
Chen W, Lin J, Zheng SG. Frequency of CD4+Foxp3+ Treg Cells Increase But is Unable to Control Nephritis in Lupus Prone Mice Hong Kong Journal of Nephrology. 17: S57. DOI: 10.1016/J.Hkjn.2015.08.150 |
0.389 |
|
| 2014 |
Gu J, Lu L, Chen M, Xu L, Lan Q, Li Q, Liu Z, Chen G, Wang P, Wang X, Brand D, Olsen N, Zheng SG. TGF-β-induced CD4+Foxp3+ T cells attenuate acute graft-versus-host disease by suppressing expansion and killing of effector CD8+ cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 3388-97. PMID 25156367 DOI: 10.4049/Jimmunol.1400207 |
0.483 |
|
| 2014 |
Su W, Wan Q, Han L, Huang J, Chen X, Chen G, Zheng SG, Liang D. Doxycycline exerts multiple anti-allergy effects to attenuate murine allergic conjunctivitis and systemic anaphylaxis. Biochemical Pharmacology. 91: 359-68. PMID 25128381 DOI: 10.1016/J.Bcp.2014.08.001 |
0.411 |
|
| 2014 |
Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, Wang J, Chen M, Liu Y, Shen Y, Brand DD, Ryffel B, Horwitz DA, Quismorio FP, Liu Z, ... ... Zheng SG, et al. Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proceedings of the National Academy of Sciences of the United States of America. 111: E3432-40. PMID 25099355 DOI: 10.1073/Pnas.1408780111 |
0.646 |
|
| 2014 |
Li Z, Lin F, Zhuo C, Deng G, Chen Z, Yin S, Gao Z, Piccioni M, Tsun A, Cai S, Zheng SG, Zhang Y, Li B. PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation. The Journal of Biological Chemistry. 289: 26872-81. PMID 25096571 DOI: 10.1074/Jbc.M114.586651 |
0.457 |
|
| 2014 |
Lin S, Yang X, Liang D, Zheng SG. Treg cells: a potential regulator for IL-22 expression? International Journal of Clinical and Experimental Pathology. 7: 474-80. PMID 24551268 |
0.362 |
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| 2014 |
Yang X, Zheng SG. Interleukin-22: a likely target for treatment of autoimmune diseases. Autoimmunity Reviews. 13: 615-20. PMID 24418299 DOI: 10.1016/J.Autrev.2013.11.008 |
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Chen M, Lin X, Liu Y, Li Q, Deng Y, Liu Z, Brand D, Guo Z, He X, Ryffel B, Zheng SG. The function of BAFF on T helper cells in autoimmunity. Cytokine & Growth Factor Reviews. 25: 301-5. PMID 24411564 DOI: 10.1016/J.Cytogfr.2013.12.011 |
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Ma J, Liu Y, Li Y, Gu J, Liu J, Tang J, Wang J, Ryffel B, Shen Y, Brand D, Liu Z, Zheng SG. Differential role of all-trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells. Journal of Leukocyte Biology. 95: 275-83. PMID 24082012 DOI: 10.1189/Jlb.0513297 |
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Liu Y, Lan Q, Lu L, Chen M, Xia Z, Ma J, Wang J, Fan H, Shen Y, Ryffel B, Brand D, Quismorio F, Liu Z, Horwitz DA, Xu A, ... Zheng SG, et al. Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. Journal of Molecular Cell Biology. 6: 81-92. PMID 23861553 DOI: 10.1093/Jmcb/Mjt026 |
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Pan HF, Leng RX, Li XP, Zheng SG, Ye DQ. Targeting T-helper 9 cells and interleukin-9 in autoimmune diseases. Cytokine & Growth Factor Reviews. 24: 515-22. PMID 25215394 DOI: 10.1016/J.Cytogfr.2013.09.001 |
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Wang P, Zheng SG. Regulatory T cells and B cells: implication on autoimmune diseases. International Journal of Clinical and Experimental Pathology. 6: 2668-74. PMID 24294353 |
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Lu L, Feng M, Gu J, Xia Z, Zhang H, Zheng S, Duan Z, Hu R, Wang J, Shi W, Ji C, Shen Y, Chen G, Zheng SG, Han YP. Restoration of intrahepatic regulatory T cells through MMP-9/13-dependent activation of TGF-β is critical for immune homeostasis following acute liver injury. Journal of Molecular Cell Biology. 5: 369-79. PMID 24280647 DOI: 10.1093/Jmcb/Mjt042 |
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Horwitz DA, Pan S, Ou JN, Wang J, Chen M, Gray JD, Zheng SG. Therapeutic polyclonal human CD8+ CD25+ Fox3+ TNFR2+ PD-L1+ regulatory cells induced ex-vivo. Clinical Immunology (Orlando, Fla.). 149: 450-63. PMID 24211847 DOI: 10.1016/J.Clim.2013.08.007 |
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| 2013 |
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, ... ... Zheng SG, et al. The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3. Immunity. 39: 272-85. PMID 23973223 DOI: 10.1016/J.Immuni.2013.08.006 |
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Zheng SG. Regulatory T cells vs Th17: differentiation of Th17 versus Treg, are the mutually exclusive? American Journal of Clinical and Experimental Immunology. 2: 94-106. PMID 23885327 |
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Li N, Wang JC, Liang TH, Zhu MH, Wang JY, Fu XL, Zhou JR, Zheng SG, Chan P, Han J. Pathologic finding of increased expression of interleukin-17 in the synovial tissue of rheumatoid arthritis patients. International Journal of Clinical and Experimental Pathology. 6: 1375-9. PMID 23826419 |
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Chen M, Su W, Lin X, Guo Z, Wang J, Zhang Q, Brand D, Ryffel B, Huang J, Liu Z, He X, Le AD, Zheng SG. Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation. Arthritis and Rheumatism. 65: 1181-93. PMID 23400582 DOI: 10.1002/Art.37894 |
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Tan Z, Jiang R, Wang X, Wang Y, Lu L, Liu Q, Zheng SG, Sun B, Ryffel B. RORγt+IL-17+ neutrophils play a critical role in hepatic ischemia-reperfusion injury. Journal of Molecular Cell Biology. 5: 143-6. PMID 23362310 DOI: 10.1093/Jmcb/Mjs065 |
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Lin X, Chen M, Liu Y, Guo Z, He X, Brand D, Zheng SG. Advances in distinguishing natural from induced Foxp3(+) regulatory T cells. International Journal of Clinical and Experimental Pathology. 6: 116-23. PMID 23329997 |
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Pan HF, Leng RX, Feng CC, Li XP, Chen GM, Li BZ, Xu WD, Zheng SG, Ye DQ. Expression profiles of Th17 pathway related genes in human systemic lupus erythematosus. Molecular Biology Reports. 40: 391-9. PMID 23054011 DOI: 10.1007/S11033-012-2073-2 |
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Pan HF, Li XP, Zheng SG, Ye DQ. Emerging role of interleukin-22 in autoimmune diseases. Cytokine & Growth Factor Reviews. 24: 51-7. PMID 22906768 DOI: 10.1016/J.Cytogfr.2012.07.002 |
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Ramalingam R, Larmonier CB, Thurston RD, Midura-Kiela MT, Zheng SG, Ghishan FK, Kiela PR. Dendritic cell-specific disruption of TGF-β receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 189: 3878-93. PMID 22972928 DOI: 10.4049/Jimmunol.1201029 |
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Zheng SG. Frontiers in immunology and immune tolerance: new perspectives. Journal of Molecular Cell Biology. 4: 266-7. PMID 22824556 DOI: 10.1093/Jmcb/Mjs028 |
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Xu W, Lan Q, Chen M, Chen H, Zhu N, Zhou X, Wang J, Fan H, Yan CS, Kuang JL, Warburton D, Togbe D, Ryffel B, Zheng SG, Shi W. Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. Plos One. 7: e40314. PMID 22792275 DOI: 10.1371/Journal.Pone.0040314 |
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Lan Q, Zhou X, Fan H, Chen M, Wang J, Ryffel B, Brand D, Ramalingam R, Kiela PR, Horwitz DA, Liu Z, Zheng SG. Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome. Journal of Molecular Cell Biology. 4: 409-19. PMID 22773728 DOI: 10.1093/Jmcb/Mjs040 |
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Kong N, Lan Q, Chen M, Zheng T, Su W, Wang J, Yang Z, Park R, Dagliyan G, Conti PS, Brand D, Liu Z, Zou H, Stohl W, Zheng SG. Induced T regulatory cells suppress osteoclastogenesis and bone erosion in collagen-induced arthritis better than natural T regulatory cells. Annals of the Rheumatic Diseases. 71: 1567-72. PMID 22764040 DOI: 10.1136/Annrheumdis-2011-201052 |
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Su W, Fan H, Chen M, Wang J, Brand D, He X, Quesniaux V, Ryffel B, Zhu L, Liang D, Zheng SG. Induced CD4+ forkhead box protein-positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1. The Journal of Allergy and Clinical Immunology. 130: 444-52.e7. PMID 22738679 DOI: 10.1016/J.Jaci.2012.05.011 |
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Chen M, Guo Z, Ju W, Ryffel B, He X, Zheng SG. The development and function of follicular helper T cells in immune responses. Cellular & Molecular Immunology. 9: 375-9. PMID 22659733 DOI: 10.1038/Cmi.2012.18 |
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Kong N, Lan Q, Chen M, Wang J, Shi W, Horwitz DA, Quesniaux V, Ryffel B, Liu Z, Brand D, Zou H, Zheng SG. Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. Arthritis and Rheumatism. 64: 2548-58. PMID 22605463 DOI: 10.1002/Art.34513 |
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Besnard AG, Togbe D, Couillin I, Tan Z, Zheng SG, Erard F, Le Bert M, Quesniaux V, Ryffel B. Inflammasome-IL-1-Th17 response in allergic lung inflammation. Journal of Molecular Cell Biology. 4: 3-10. PMID 22147847 DOI: 10.1093/Jmcb/Mjr042 |
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Zheng SG. Emerging topics and new perspectives on regulatory and effector T cells. Journal of Molecular Cell Biology. 4: 1-2. PMID 22140270 DOI: 10.1093/Jmcb/Mjr044 |
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Lan Q, Fan H, Quesniaux V, Ryffel B, Liu Z, Zheng SG. Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases? Journal of Molecular Cell Biology. 4: 22-8. PMID 22107826 DOI: 10.1093/Jmcb/Mjr039 |
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| 2011 |
Kida Y, Xia Z, Zheng S, Mordwinkin NM, Louie SG, Zheng SG, Feng M, Shi H, Duan Z, Han YP. Interleukin-1 as an injury signal mobilizes retinyl esters in hepatic stellate cells through down regulation of lecithin retinol acyltransferase. Plos One. 6: e26644. PMID 22073179 DOI: 10.1371/Journal.Pone.0026644 |
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Lu L, Ma J, Li Z, Lan Q, Chen M, Liu Y, Xia Z, Wang J, Han Y, Shi W, Quesniaux V, Ryffel B, Brand D, Li B, Liu Z, ... Zheng SG, et al. All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus. Plos One. 6: e24590. PMID 21931768 DOI: 10.1371/Journal.Pone.0024590 |
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Zhou X, Xia Z, Lan Q, Wang J, Su W, Han YP, Fan H, Liu Z, Stohl W, Zheng SG. BAFF promotes Th17 cells and aggravates experimental autoimmune encephalomyelitis. Plos One. 6: e23629. PMID 21897850 DOI: 10.1371/Journal.Pone.0023629 |
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Shi Q, Cao H, Liu J, Zhou X, Lan Q, Zheng S, Liu Z, Li Q, Fan H. CD4+ Foxp3+ regulatory T cells induced by TGF-β, IL-2 and all-trans retinoic acid attenuate obliterative bronchiolitis in rat trachea transplantation. International Immunopharmacology. 11: 1887-94. PMID 21839859 DOI: 10.1016/J.Intimp.2011.07.020 |
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Huang Z, Fu B, Zheng SG, Li X, Sun R, Tian Z, Wei H. Involvement of CD226+ NK cells in immunopathogenesis of systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 186: 3421-31. PMID 21296979 DOI: 10.4049/Jimmunol.1000569 |
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Qian X, Wang K, Wang X, Zheng SG, Lu L. Generation of human regulatory T cells de novo with suppressive function prevent xenogeneic graft versus host disease. International Immunopharmacology. 11: 630-7. PMID 21147213 DOI: 10.1016/J.Intimp.2010.11.036 |
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Zhou X, Kong N, Zou H, Brand D, Li X, Liu Z, Zheng SG. Therapeutic potential of TGF-β-induced CD4(+) Foxp3(+) regulatory T cells in autoimmune diseases. Autoimmunity. 44: 43-50. PMID 20670119 DOI: 10.3109/08916931003782163 |
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| 2010 |
Lu L, Zhou X, Wang J, Zheng SG, Horwitz DA. Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid. Plos One. 5: e15150. PMID 21179414 DOI: 10.1371/Journal.Pone.0015150 |
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Hu G, Liu Z, Zheng C, Zheng SG. Antigen-non-specific regulation centered on CD25+Foxp3+ Treg cells. Cellular & Molecular Immunology. 7: 414-8. PMID 20729905 DOI: 10.1038/Cmi.2010.39 |
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Fan H, Zheng SG. Frontiers in Clinical Immunology and Immunoregulation 2010: The Highlight Journal of Molecular Cell Biology. 2: 240-242. PMID 20716549 DOI: 10.1093/Jmcb/Mjq018 |
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Zhou X, Kong N, Wang J, Fan H, Zou H, Horwitz D, Brand D, Liu Z, Zheng SG. Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu. Journal of Immunology (Baltimore, Md. : 1950). 185: 2675-9. PMID 20679534 DOI: 10.4049/Jimmunol.1000598 |
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Ma J, Yu J, Tao X, Cai L, Wang J, Zheng SG. The imbalance between regulatory and IL-17-secreting CD4+ T cells in lupus patients. Clinical Rheumatology. 29: 1251-8. PMID 20563617 DOI: 10.1007/S10067-010-1510-7 |
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Zhou X, Wang J, Shi W, Brand DD, Liu Z, Fan H, Zheng SG. Isolation of purified and live Foxp3+ regulatory T cells using FACS sorting on scatter plot. Journal of Molecular Cell Biology. 2: 164-9. PMID 20430855 DOI: 10.1093/Jmcb/Mjq007 |
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| 2010 |
Lu L, Wang J, Zhang F, Chai Y, Brand D, Wang X, Horwitz DA, Shi W, Zheng SG. Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 4295-306. PMID 20304828 DOI: 10.4049/Jimmunol.0903418 |
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| 2010 |
Lu L, Ma J, Wang X, Wang J, Zhang F, Yu J, He G, Xu B, Brand DD, Horwitz DA, Shi W, Zheng SG. Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg. European Journal of Immunology. 40: 142-52. PMID 19943263 DOI: 10.1002/Eji.200939618 |
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Lan Q, Zhou X, Shi W, Fan H, Brand D, Liu Z, Zheng SG. Isolation of Purified and Live Foxp3+ Regulatory T Cells Using FACS Sorting on Scatter Plot Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.364 |
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Shi Q, Niu Y, Fan H, Zheng SG, Liu Z. CD28 Superagonist Antibody Treatment Attenuates Development of Obliterative Airway Disease in Rat Allo-orthotopic Tracheal Transplant Model Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.274 |
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| 2010 |
Zheng SG, Lu L, Wang J, Zhang F, Brand D, Horwitz D, Wang X, Shi W. Role of Smad and non-Smad Signals in the Development of Th17 and Regulatory T Cells Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.209 |
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| 2010 |
Lu L, Wang J, Zheng SG, Horwitz D. Retinoic Acid, IL-2 and TGF-β can Rapidly Induce Naïve Human CD4+ Cells to Become CD25+Foxp3+ Regulatory Cells with Protective Activity in vivo Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.096 |
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Zhou X, Wang J, Liu Z, Stohl W, Zheng SG. Opposing Roles for BAFF and CTLA-4 in the Development of IL-17-producing or Foxp3+ T Regulatory (Treg) Cells Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.086 |
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| 2010 |
Shi Q, Cao H, Lan Q, Zheng SG, Fan H. CD4+Foxp3+ T Cells Generated ex vivo with TGF-β and atRA Attenuate Rat Trachea Transplant Rejection Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.075 |
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| 2010 |
Zheng SG, Kong N, Zhou X, Wang J, Zou H, Liu Z, Brand D. TGF-β-induced CD4+Foxp3+ Cells but not Natural CD4+CD25+ Cells Suppress Established Collagen-induced Arthritis Clinical Immunology. 135: S22. DOI: 10.1016/J.Clim.2010.03.071 |
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| 2009 |
Lu L, Yu Y, Li G, Pu L, Zhang F, Zheng S, Wang X. CD8(+)CD103(+) regulatory T cells in spontaneous tolerance of liver allografts. International Immunopharmacology. 9: 546-548. PMID 19539566 DOI: 10.1016/J.Intimp.2009.01.021 |
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Jacob N, Yang H, Pricop L, Liu Y, Gao X, Zheng SG, Wang J, Gao HX, Putterman C, Koss MN, Stohl W, Jacob CO. Accelerated pathological and clinical nephritis in systemic lupus erythematosus-prone New Zealand Mixed 2328 mice doubly deficient in TNF receptor 1 and TNF receptor 2 via a Th17-associated pathway. Journal of Immunology (Baltimore, Md. : 1950). 182: 2532-41. PMID 19201910 DOI: 10.4049/Jimmunol.0802948 |
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Li D, Li X, Li X, Wang G, Ma Y, Zhao S, Zheng S. [Expression of FOXP3 in CD4+ CD39+ T cells of patients with systemic lupus erythematosus and dynamic observation of treatment with glucocorticoid]. National Medical Journal of China. 89: 1636-1638. DOI: 10.3760/Cma.J.Issn.0376-2491.2009.23.015 |
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| 2009 |
Zheng SG, Lu L, Wang J, Brand D, Horwitz D, Shi W. F.49. Neither Smad2 or Smad3 is Essential for TGF-β to Induce Foxp3+ Regulatory T Cells and Th17 Cells Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.313 |
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| 2009 |
Zheng SG, Lu L, Li B, Wang J, Brand D, Shi W, Horwitz D. OR.101. All-trans Retinoic Acid Promotes the Differentiation of iTreg Cells via Smad and Non-Smad Signaling Pathways Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.116 |
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| 2009 |
Lu L, Wang J, Wang X, Zhang F, Luo J, Brand D, Horwitz D, Zheng SG. OR.60. Characteristics of CD8+CD25-Cells Induced to Become Suppressor Cells ex-vivo with IL-2 and TGF-β Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.072 |
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| 2008 |
Tao X, Ma J, Zhang Y, Yu J, Cai L, Wang J, Zheng SG. Neutralization of IL-4 and IFN-γ Facilitates inducing TGF-β-induced CD4(+)Foxp3(+) Regulatory Cells. International Journal of Biomedical Science : Ijbs. 4: 52-7. PMID 23675066 |
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| 2008 |
Zheng SG. The Critical Role of TGF-beta1 in the Development of Induced Foxp3+ Regulatory T Cells. International Journal of Clinical and Experimental Medicine. 1: 192-202. PMID 19079658 |
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| 2008 |
Horwitz DA, Zheng SG, Gray JD. Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other. Trends in Immunology. 29: 429-35. PMID 18676178 DOI: 10.1016/J.It.2008.06.005 |
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| 2008 |
Zheng SG, Wang J, Horwitz DA. Cutting Edge: Foxp3+CD4+CD25+ Regulatory T Cells Induced by IL-2 and TGF-β Are Resistant to Th17 Conversion by IL-6 Journal of Immunology. 180: 7112-7116. PMID 18490709 DOI: 10.4049/Jimmunol.180.11.7112 |
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| 2008 |
Horwitz DA, Zheng SG, Wang J, Gray JD. Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg. European Journal of Immunology. 38: 912-5. PMID 18395858 DOI: 10.1002/Eji.200738109 |
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| 2008 |
Zhao S, Li X, Li X, Zhai Z, Chen Z, Ma Y, Zhang H, Zheng S. [Expression of CD4+ CD25+ CD127(low/-) T cells in patients with systemic lupus erythematosus]. National Medical Journal of China. 88: 453-456. DOI: 10.3321/J.Issn:0376-2491.2008.07.007 |
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| 2008 |
Zheng SG, Wang J, Gray JD, Cava AL, Hahn B, Horwitz D. Sa.28. Protective Effects of Polyclonal Foxp3+CD4+CD25+ Cells Induced Ex-Vivo on SLE Mouse Models Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.249 |
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| 2008 |
Zheng SG, Wang J, Horwitz D. OR.42. IL-6 Induces Natural Foxp3+ but Not TGF-β-induced CD4+CD25+ Cells to Become Th17 Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.048 |
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| 2007 |
Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 2018-27. PMID 17277105 DOI: 10.4049/Jimmunol.178.4.2018 |
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| 2007 |
Zheng SG, Wang J, Ye S, Sehy D, Palian B, Horwitz DA. Comparison of Membrane-bound and Secreted TGFβ by IL-2 Activated Natural and Adaptive CD4+CD25+ Regulatory Cells from Healthy and Lupus-prone Mice Clinical Immunology. 123: S122-S123. DOI: 10.1016/J.Clim.2007.03.527 |
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| 2007 |
Zheng SG, Wang J, Ye S, Horwitz DA. Polyclonal CD4+CD25+ Regulatory T Cells Induced With TGF-β Prevent a Stimulatory Graft-Versus-Host Disease With a Lupus-Like Syndrome Clinical Immunology. 123. DOI: 10.1016/J.Clim.2007.03.015 |
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| 2006 |
Zheng SG, Wang JH, Stohl W, Kim KS, Gray JD, Horwitz DA. TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 3321-9. PMID 16517699 DOI: 10.4049/Jimmunol.176.6.3321 |
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| 2006 |
Zheng SG, Meng L, Wang JH, Watanabe M, Barr ML, Cramer DV, Gray JD, Horwitz DA. Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient. International Immunology. 18: 279-89. PMID 16415106 DOI: 10.1093/Intimm/Dxh368 |
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| 2004 |
Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. Journal of Immunology (Baltimore, Md. : 1950). 172: 5213-21. PMID 15100259 DOI: 10.4049/Jimmunol.172.9.5213 |
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Horwitz DA, Zheng SG, Gray JD, Wang JH, Ohtsuka K, Yamagiwa S. Regulatory T cells generated ex vivo as an approach for the therapy of autoimmune disease. Seminars in Immunology. 16: 135-43. PMID 15036237 DOI: 10.1016/J.Smim.2003.12.009 |
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| 2004 |
Zheng SG, Wang JH, Koss MN, Quismorio F, Gray JD, Horwitz DA. CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome. Journal of Immunology (Baltimore, Md. : 1950). 172: 1531-9. PMID 14734731 DOI: 10.4049/Jimmunol.172.3.1531 |
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Horwitz DA, Zheng SG, Gray JD. The role of the combination of IL-2 and TGF-beta or IL-10 in the generation and function of CD4+ CD25+ and CD8+ regulatory T cell subsets. Journal of Leukocyte Biology. 74: 471-8. PMID 14519757 DOI: 10.1189/Jlb.0503228 |
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| 2002 |
Zheng SG, Gray JD, Ohtsuka K, Yamagiwa S, Horwitz DA. Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors. Journal of Immunology (Baltimore, Md. : 1950). 169: 4183-9. PMID 12370347 DOI: 10.4049/Jimmunol.169.8.4183 |
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| 2002 |
Horwitz DA, Gray JD, Zheng SG. The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases. Arthritis Research. 4: 241-6. PMID 12106494 DOI: 10.1186/Ar414 |
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