Vickram Ramkumar, Ph.D. - Publications

Affiliations: 
Pharmacology Southern Illinois University School of Medicine, Springfield, IL, United States 

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Al Aameri RFH, Alanisi EMA, Oluwatosin A, Al Sallami D, Sheth S, Alberts I, Patel S, Rybak LP, Ramkumar V. Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity. Frontiers in Immunology. 14: 1125948. PMID 37063917 DOI: 10.3389/fimmu.2023.1125948  0.306
2021 Ramkumar V, Mukherjea D, Dhukhwa A, Rybak LP. Oxidative Stress and Inflammation Caused by Cisplatin Ototoxicity. Antioxidants (Basel, Switzerland). 10. PMID 34943021 DOI: 10.3390/antiox10121919  0.318
2021 Dhukhwa A, Al Aameri RFH, Sheth S, Mukherjea D, Rybak L, Ramkumar V. Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss. Scientific Reports. 11: 8116. PMID 33854102 DOI: 10.1038/s41598-021-87387-5  0.3
2021 Rosati R, Shahab M, Ramkumar V, Jamesdaniel S. Lmo4 Deficiency Enhances Susceptibility to Cisplatin-Induced Cochlear Apoptosis and Hearing Loss. Molecular Neurobiology. PMID 33411315 DOI: 10.1007/s12035-020-02226-4  0.302
2020 Mukherjea D, Dhukhwa A, Sapra A, Bhandari P, Woolford K, Franke J, Ramkumar V, Rybak L. Strategies to reduce the risk of platinum containing antineoplastic drug-induced ototoxicity. Expert Opinion On Drug Metabolism & Toxicology. PMID 32757852 DOI: 10.1080/17425255.2020.1806235  0.345
2019 Dhukhwa A, Bhatta P, Sheth S, Korrapati K, Tieu C, Mamillapalli C, Ramkumar V, Mukherjea D. Targeting Inflammatory Processes Mediated by TRPVI and TNF-α for Treating Noise-Induced Hearing Loss. Frontiers in Cellular Neuroscience. 13: 444. PMID 31632242 DOI: 10.3389/Fncel.2019.00444  0.34
2019 Rybak LP, Dhukhwa A, Mukherjea D, Ramkumar V. Local Drug Delivery for Prevention of Hearing Loss. Frontiers in Cellular Neuroscience. 13: 300. PMID 31338024 DOI: 10.3389/Fncel.2019.00300  0.328
2019 Sheth S, Sheehan K, Dhukhwa A, Al Aameri RFH, Mamillapalli C, Mukherjea D, Rybak LP, Ramkumar V. Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss. Scientific Reports. 9: 9571. PMID 31267026 DOI: 10.1038/S41598-019-45964-9  0.429
2019 Rybak LP, Mukherjea D, Ramkumar V. Mechanisms of Cisplatin-Induced Ototoxicity and Prevention. Seminars in Hearing. 40: 197-204. PMID 31036996 DOI: 10.1055/S-0039-1684048  0.401
2019 Bhatta P, Dhukhwa A, Sheehan K, Al Aameri RFH, Borse V, Ghosh S, Sheth S, Mamillapalli C, Rybak L, Ramkumar V, Mukherjea D. Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea. Scientific Reports. 9: 4131. PMID 30858408 DOI: 10.1038/S41598-019-40425-9  0.412
2018 Ghosh S, Sheth S, Sheehan K, Mukherjea D, Dhukhwa A, Borse V, Rybak LP, Ramkumar V. The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss. Frontiers in Cellular Neuroscience. 12: 271. PMID 30186120 DOI: 10.3389/Fncel.2018.00271  0.429
2017 Sheth S, Mukherjea D, Rybak LP, Ramkumar V. Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection. Frontiers in Cellular Neuroscience. 11: 338. PMID 29163050 DOI: 10.3389/Fncel.2017.00338  0.439
2017 Borse V, Al Aameri RFH, Sheehan K, Sheth S, Kaur T, Mukherjea D, Tupal S, Lowy M, Ghosh S, Dhukhwa A, Bhatta P, Rybak LP, Ramkumar V. Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity. Cell Death & Disease. 8: e2921. PMID 28703809 DOI: 10.1038/Cddis.2017.314  0.595
2017 Al Aameri RFH, Sheth S, Alanisi EMA, Borse V, Mukherjea D, Rybak LP, Ramkumar V. Tonic suppression of PCAT29 by the IL-6 signaling pathway in prostate cancer: Reversal by resveratrol. Plos One. 12: e0177198. PMID 28467474 DOI: 10.1371/Journal.Pone.0177198  0.361
2016 Kaur T, Borse V, Sheth S, Sheehan K, Ghosh S, Tupal S, Jajoo S, Mukherjea D, Rybak LP, Ramkumar V. Adenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3962-77. PMID 27053204 DOI: 10.1523/Jneurosci.3111-15.2016  0.607
2014 Brito R, Sheth S, Mukherjea D, Rybak LP, Ramkumar V. TRPV1: A Potential Drug Target for Treating Various Diseases. Cells. 3: 517-45. PMID 24861977 DOI: 10.3390/Cells3020517  0.311
2014 Sheth S, Brito R, Mukherjea D, Rybak LP, Ramkumar V. Adenosine receptors: expression, function and regulation. International Journal of Molecular Sciences. 15: 2024-52. PMID 24477263 DOI: 10.3390/Ijms15022024  0.376
2013 Jajoo S, Mukherjea D, Kaur T, Sheehan KE, Sheth S, Borse V, Rybak LP, Ramkumar V. Essential role of NADPH oxidase-dependent reactive oxygen species generation in regulating microRNA-21 expression and function in prostate cancer. Antioxidants & Redox Signaling. 19: 1863-76. PMID 23682737 DOI: 10.1089/Ars.2012.4820  0.539
2013 Sheth S, Jajoo S, Mukherjea D, Sheehan K, Rybak LP, Ramkumar V. Abstract 4084: Resveratrol attenuates prostate cancer growth by inhibiting insulin-like growth factor-1 receptor signaling. Cancer Research. 73: 4084-4084. DOI: 10.1158/1538-7445.Am2013-4084  0.362
2012 Sheth S, Jajoo S, Kaur T, Mukherjea D, Sheehan K, Rybak LP, Ramkumar V. Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway. Plos One. 7: e51655. PMID 23272133 DOI: 10.1371/Journal.Pone.0051655  0.556
2012 Rybak LP, Mukherjea D, Jajoo S, Kaur T, Ramkumar V. siRNA-mediated knock-down of NOX3: therapy for hearing loss? Cellular and Molecular Life Sciences : Cmls. 69: 2429-34. PMID 22562580 DOI: 10.1007/S00018-012-1016-3  0.587
2012 Jajoo S, Kaur T, Mukherjea D, Sheehan K, Sheth S, Rybak LP, Ramkumar V. Abstract 1940: Anti-tumor action of adenosine A3 receptor in prostate cancer involves suppression of micro RNA-21 Cancer Research. 72: 1940-1940. DOI: 10.1158/1538-7445.Am2012-1940  0.546
2012 Sheth SB, Jajoo S, Mukherjea D, Kaur T, Sheehan K, Rybak L, Ramkumar V. Abstract 1093: Resveratrol inhibits prostate cancer metastasis by targeting microRNA-21 Cancer Research. 72: 1093-1093. DOI: 10.1158/1538-7445.Am2012-1093  0.55
2011 Mukherjea D, Rybak LP, Sheehan KE, Kaur T, Ramkumar V, Jajoo S, Sheth S. The design and screening of drugs to prevent acquired sensorineural hearing loss. Expert Opinion On Drug Discovery. 6: 491-505. PMID 22646075 DOI: 10.1517/17460441.2011.562887  0.513
2011 Ramkumar V, Jhaveri KA, Xie X, Jajoo S, Toth LA. Nuclear Factor κB and Adenosine Receptors: Biochemical and Behavioral Profiling. Current Neuropharmacology. 9: 342-9. PMID 22131942 DOI: 10.2174/157015911795596559  0.397
2011 Kaur T, Mukherjea D, Sheehan K, Jajoo S, Rybak LP, Ramkumar V. Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation. Cell Death & Disease. 2: e180. PMID 21776018 DOI: 10.1038/Cddis.2011.63  0.593
2011 Mukherjea D, Jajoo S, Sheehan K, Kaur T, Sheth S, Bunch J, Perro C, Rybak LP, Ramkumar V. NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing loss. Antioxidants & Redox Signaling. 14: 999-1010. PMID 20712533 DOI: 10.1089/Ars.2010.3497  0.6
2011 Jajoo S, Mukherjea D, Sheehan K, Kaur T, Sheth S, Rybak LP, Ramkumar V. Abstract 1184: NADPH oxidase-dependent reactive oxygen species generation regulate micro RNA-21 in prostate cancer Cancer Research. 71: 1184-1184. DOI: 10.1158/1538-7445.Am2011-1184  0.54
2011 Sheth S, Jajoo S, Mukherjea D, Kaur T, Sheehan K, Ramkumar V. Abstract 1152: Micro RNA-21 serves as an essential target for resveratrol's anti-tumor action against metastatic prostate cancer cells Cancer Research. 71: 1152-1152. DOI: 10.1158/1538-7445.Am2011-1152  0.554
2010 Mukherjea D, Jajoo S, Kaur T, Sheehan KE, Ramkumar V, Rybak LP. Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat. Antioxidants & Redox Signaling. 13: 589-98. PMID 20214492 DOI: 10.1089/Ars.2010.3110  0.586
2010 Jajoo S, Mukherjea D, Kumar S, Sheth S, Kaur T, Rybak LP, Ramkumar V. Role of beta-arrestin1/ERK MAP kinase pathway in regulating adenosine A1 receptor desensitization and recovery. American Journal of Physiology. Cell Physiology. 298: C56-65. PMID 19828838 DOI: 10.1152/Ajpcell.00190.2009  0.563
2009 Jajoo S, Mukherjea D, Watabe K, Ramkumar V. Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity. Neoplasia (New York, N.Y.). 11: 1132-45. PMID 19881949 DOI: 10.1593/Neo.09744  0.41
2008 Mukherjea D, Jajoo S, Whitworth C, Bunch JR, Turner JG, Rybak LP, Ramkumar V. Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13056-65. PMID 19052196 DOI: 10.1523/Jneurosci.1307-08.2008  0.453
2008 Jajoo S, Mukherjea D, Brewer GJ, Ramkumar V. Pertussis toxin B-oligomer suppresses human immunodeficiency virus-1 Tat-induced neuronal apoptosis through feedback inhibition of phospholipase C-beta by protein kinase C. Neuroscience. 151: 525-32. PMID 18093742 DOI: 10.1016/J.Neuroscience.2007.11.010  0.332
2007 Xie X, Jhaveri KA, Ding M, Hughes LF, Toth LA, Ramkumar V. Expression of striatal adenosine and dopamine receptors in mice deficient in the p50 subunit of NF-kappaB. Life Sciences. 81: 1031-41. PMID 17869311 DOI: 10.1016/J.Lfs.2007.07.031  0.305
2007 Pingle SC, Jajoo S, Mukherjea D, Sniderhan LF, Jhaveri KA, Marcuzzi A, Rybak LP, Maggirwar SB, Ramkumar V. Activation of the adenosine A1 receptor inhibits HIV-1 tat-induced apoptosis by reducing nuclear factor-kappaB activation and inducible nitric-oxide synthase. Molecular Pharmacology. 72: 856-67. PMID 17609415 DOI: 10.1124/Mol.106.031427  0.635
2007 Jhaveri KA, Reichensperger J, Toth LA, Sekino Y, Ramkumar V. Reduced basal and lipopolysaccharide-stimulated adenosine A1 receptor expression in the brain of nuclear factor-κB p50-/- mice Neuroscience. 146: 415-426. PMID 17350174 DOI: 10.1016/J.Neuroscience.2006.12.035  0.307
2007 Rybak LP, Whitworth CA, Mukherjea D, Ramkumar V. Mechanisms of cisplatin-induced ototoxicity and prevention. Hearing Research. 226: 157-67. PMID 17113254 DOI: 10.1016/J.Heares.2006.09.015  0.375
2006 Jhaveri KA, Toth LA, Sekino Y, Ramkumar V. Nitric oxide serves as an endogenous regulator of neuronal adenosine A1 receptor expression. Journal of Neurochemistry. 99: 42-53. PMID 16987234 DOI: 10.1111/J.1471-4159.2006.04095.X  0.422
2006 Mukherjea D, Whitworth CA, Nandish S, Dunaway GA, Rybak LP, Ramkumar V. Expression of the kidney injury molecule 1 in the rat cochlea and induction by cisplatin Neuroscience. 139: 733-740. PMID 16464536 DOI: 10.1016/J.Neuroscience.2005.12.044  0.311
2006 Jajoo S, Mukherjea D, Pingle S, Sekino Y, Ramkumar V. Induction of adenosine A1 receptor expression by pertussis toxin via an adenosine 5'-diphosphate ribosylation-independent pathway. The Journal of Pharmacology and Experimental Therapeutics. 317: 1-10. PMID 16322354 DOI: 10.1124/Jpet.105.096255  0.422
2006 Martin L, Pingle SC, Hallam DM, Rybak LP, Ramkumar V. Activation of the adenosine A3 receptor in RAW 264.7 cells inhibits lipopolysaccharide-stimulated tumor necrosis factor-alpha release by reducing calcium-dependent activation of nuclear factor-kappaB and extracellular signal-regulated kinase 1/2. The Journal of Pharmacology and Experimental Therapeutics. 316: 71-8. PMID 16188954 DOI: 10.1124/Jpet.105.091868  0.341
2005 Puntambekar P, Mukherjea D, Jajoo S, Ramkumar V. Essential role of Rac1/NADPH oxidase in nerve growth factor induction of TRPV1 expression. Journal of Neurochemistry. 95: 1689-703. PMID 16283857 DOI: 10.1111/J.1471-4159.2005.03518.X  0.391
2004 Pingle SC, Mishra S, Marcuzzi A, Bhat SG, Sekino Y, Rybak LP, Ramkumar V. Osmotic diuretics induce adenosine A1 receptor expression and protect renal proximal tubular epithelial cells against cisplatin-mediated apoptosis. The Journal of Biological Chemistry. 279: 43157-67. PMID 15272017 DOI: 10.1074/Jbc.M405666200  0.415
2004 Ramirez SH, Fan S, Maguire CA, Perry S, Hardiek K, Ramkumar V, Gelbard HA, Dewhurst S, Maggirwar SB. Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal. Journal of Neuroscience Research. 77: 258-69. PMID 15211592 DOI: 10.1002/Jnr.20150  0.707
2004 Whitworth CA, Ramkumar V, Jones B, Tsukasaki N, Rybak LP. Protection against cisplatin ototoxicity by adenosine agonists. Biochemical Pharmacology. 67: 1801-7. PMID 15081879 DOI: 10.1016/J.Bcp.2004.01.010  0.422
2004 Puntambekar P, Van Buren J, Raisinghani M, Premkumar LS, Ramkumar V. Direct interaction of adenosine with the TRPV1 channel protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3663-71. PMID 15071115 DOI: 10.1523/Jneurosci.4773-03.2004  0.415
2004 Ramkumar V, Whitworth CA, Pingle SC, Hughes LF, Rybak LP. Noise induces A1 adenosine receptor expression in the chinchilla cochlea. Hearing Research. 188: 47-56. PMID 14759570 DOI: 10.1016/S0378-5955(03)00344-7  0.351
2003 Pingle SC, Sanchez JF, Hallam DM, Williamson AL, Maggirwar SB, Ramkumar V. Hypertonicity inhibits lipopolysaccharide-induced nitric oxide synthase expression in smooth muscle cells by inhibiting nuclear factor kappaB. Molecular Pharmacology. 63: 1238-47. PMID 12761333 DOI: 10.1124/Mol.63.6.1238  0.613
2002 Bhat SG, Mishra S, Mei Y, Nie Z, Whitworth CA, Rybak LP, Ramkumar V. Cisplatin up-regulates the adenosine A(1) receptor in the rat kidney. European Journal of Pharmacology. 442: 251-64. PMID 12065079 DOI: 10.1016/S0014-2999(02)01510-8  0.406
2001 Ramkumar V, Hallam DM, Nie Z. Adenosine, oxidative stress and cytoprotection Japanese Journal of Pharmacology. 86: 265-274. PMID 11488425 DOI: 10.1254/Jjp.86.265  0.39
2001 Hardiek K, Katholi RE, Ramkumar V, Deitrick C. Proximal tubule cell response to radiographic contrast media American Journal of Physiology - Renal Physiology. 280: F61-F70. PMID 11133515 DOI: 10.1152/Ajprenal.2001.280.1.F61  0.316
1999 Malek RL, Nie Z, Ramkumar V, Lee NH. Adenosine A(2A) receptor mRNA regulation by nerve growth factor is TrkA- , Src-, and Ras-dependent via extracellular regulated kinase and stress- activated protein kinase/c-Jun NH2-terminal kinase Journal of Biological Chemistry. 274: 35499-35504. PMID 10585422 DOI: 10.1074/Jbc.274.50.35499  0.366
1999 Bhat SG, Nie Z, Ramkumar V. Cisplatin up-regulates adenosine A1 receptors in rat testes European Journal of Pharmacology. 382: 35-43. PMID 10556502 DOI: 10.1016/S0014-2999(99)00584-1  0.403
1999 Nie Z, Mei Y, Malek RL, Marcuzzi A, Lee NH, Ramkumar V. A role of p75 in NGF-mediated down-regulation of the A(2A) adenosine receptors in PC12 cells Molecular Pharmacology. 56: 947-954. PMID 10531399 DOI: 10.1124/Mol.56.5.947  0.4
1998 Bhat SG, Wilson M, Ramkumar V. Age-dependent reductions in A1 adenosine receptor expression in rat testes American Journal of Physiology - Cell Physiology. 274: C1057-C1064. PMID 9575803 DOI: 10.1152/Ajpcell.1998.274.4.C1057  0.356
1998 Nie Z, Mei Y, Ford M, Rybak L, Marcuzzi A, Ren H, Stiles GL, Ramkumar V. Oxidative stress increases A1 adenosine receptor expression by activating nuclear factor κB Molecular Pharmacology. 53: 663-669. PMID 9547356 DOI: 10.1124/Mol.53.4.663  0.416
1997 Ford MS, Nie Z, Whitworth C, Rybak LP, Ramkumar V. Up-regulation of adenosine receptors in the cochlea by cisplatin Hearing Research. 111: 143-152. PMID 9307320 DOI: 10.1016/S0378-5955(97)00103-2  0.402
1997 Nie Z, Mei Y, Ramkumar V. Short term desensitization of the A1 adenosine receptors in DDT1 MF-2 cells Molecular Pharmacology. 52: 456-464. PMID 9281608 DOI: 10.1124/Mol.52.3.456  0.398
1997 Ford MS, Maggirwar SB, Rybak LP, Whitworth C, Ramkumar V. Expression and function of adenosine receptors in the chinchilla cochlea. Hearing Research. 105: 130-40. PMID 9083810 DOI: 10.1016/S0378-5955(96)00204-3  0.619
1997 NIE Z, RYBAK L, RAMKUMAR V, FORD M, WHITWORTH C, MEI Y. Up-regulation of A1 adenosine receptors by cisplatin following in vivo and in vitro administration Otolaryngology - Head and Neck Surgery. 117: P72-P72. DOI: 10.1016/S0194-5998(97)80075-7  0.349
1995 Ramkumar V, Nie Z, Rybak LP, Maggirwar SB. Adenosine, antioxidant enzymes and cytoprotection. Trends in Pharmacological Sciences. 16: 283-5. PMID 7482990 DOI: 10.1016/S0165-6147(00)89051-3  0.55
1994 Beaven MA, Ramkumar V, Ali H. Adenosine A3 receptors in mast cells. Trends in Pharmacological Sciences. 15: 13-4. PMID 8140652 DOI: 10.1016/0165-6147(94)90124-4  0.335
1994 Maggirwar SB, Dhanraj DN, Somani SM, Ramkumar V. Adenosine acts as an endogenous activator of the cellular antioxidant defense system. Biochemical and Biophysical Research Communications. 201: 508-15. PMID 8002980 DOI: 10.1006/Bbrc.1994.1731  0.59
1994 Ramkumar V, Ravi R, Wilson MC, Gettys TW, Whitworth C, Rybak LP. Identification of A1 adenosine receptors in rat cochlea coupled to inhibition of adenylyl cyclase. The American Journal of Physiology. 267: C731-7. PMID 7943201 DOI: 10.1152/Ajpcell.1994.267.3.C731  0.371
Show low-probability matches.