| Year |
Citation |
Score |
| 2023 |
Bullert A, Li X, Zhang C, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure. Biorxiv : the Preprint Server For Biology. PMID 37609242 DOI: 10.1101/2023.06.19.544952 |
0.686 |
|
| 2023 |
Bullert A, Li X, Chunyun Z, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure. Environmental Toxicology and Pharmacology. 104245. PMID 37572994 DOI: 10.1016/j.etap.2023.104245 |
0.686 |
|
| 2022 |
Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Lehmler HJ, Ankrum JA, Klingelhutz AJ. Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3',4,4',5-Pentachlorobiphenyl (PCB126). Data in Brief. 45: 108571. PMID 36131953 DOI: 10.1016/j.dib.2022.108571 |
0.675 |
|
| 2022 |
Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Joachim-Lehmler H, Ankrum JA, Klingelhutz AJ. Transcriptome sequencing of 3,3',4,4',5-Pentachlorobiphenyl (PCB126)-treated human preadipocytes demonstrates progressive changes in pathways associated with inflammation and diabetes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 83: 105396. PMID 35618242 DOI: 10.1016/j.tiv.2022.105396 |
0.566 |
|
| 2021 |
Eti NA, Flor S, Iqbal K, Scott RL, Klenov VE, Gibson-Corley KN, Soares MJ, Ludewig G, Robertson LW. PCB126 Induced Toxic Actions on Liver Energy Metabolism is Mediated by AhR in Rats. Toxicology. 153054. PMID 34848246 DOI: 10.1016/j.tox.2021.153054 |
0.309 |
|
| 2021 |
Duffel MW, Tuttle K, Lehmler HJ, Robertson LW. Human hepatic microsomal sulfatase catalyzes the hydrolysis of polychlorinated biphenyl sulfates: A potential mechanism for retention of hydroxylated PCBs. Environmental Toxicology and Pharmacology. 88: 103757. PMID 34688910 DOI: 10.1016/j.etap.2021.103757 |
0.538 |
|
| 2020 |
Wang H, Adamcakova-Dodd A, Flor S, Gosse L, Klenov VE, Stolwijk JM, Lehmler HJ, Hornbuckle KC, Ludewig G, Robertson LW, Thorne PS. Comprehensive Subchronic Inhalation Toxicity Assessment of an Indoor School Air Mixture of PCBs. Environmental Science & Technology. PMID 33256405 DOI: 10.1021/acs.est.0c04470 |
0.493 |
|
| 2020 |
Grimm FA, Klaren WD, Li X, Lehmler HJ, Karmakar M, Robertson LW, Chiu WA, Rusyn I. Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites. Environmental Health Perspectives. 128: 77008. PMID 32701041 DOI: 10.1289/Ehp7030 |
0.499 |
|
| 2020 |
Williams AE, Watt J, Robertson LW, Gadupudi G, Osborn ML, Soares MJ, Iqbal K, Pedersen KB, Shankar K, Littleton S, Maimone C, Eti NA, Suva LJ, Ronis MJJ. Skeletal Toxicity of Coplanar Polychlorinated Biphenyl Congener 126 in the Rat is Aryl Hydrocarbon Receptor-Dependent. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32119087 DOI: 10.1093/Toxsci/Kfaa030 |
0.782 |
|
| 2019 |
Ronis MJ, Watt J, Pulliam CF, Williams AE, Alund AW, Haque E, Gadupudi GS, Robertson LW. Skeletal toxicity resulting from exposure of growing male rats to coplanar PCB 126 is associated with disruption of calcium homeostasis and the GH-IGF-1 axis and direct effects on bone formation. Archives of Toxicology. PMID 31820026 DOI: 10.1007/S00204-019-02645-W |
0.802 |
|
| 2019 |
Gourronc FA, Perdew GH, Robertson LW, Klingelhutz AJ. PCB126 blocks the thermogenic beiging response of adipocytes. Environmental Science and Pollution Research International. PMID 31721030 DOI: 10.1007/S11356-019-06663-0 |
0.601 |
|
| 2018 |
Rodriguez EA, Vanle BC, Doorn JA, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environmental Toxicology and Pharmacology. 62: 69-78. PMID 29986280 DOI: 10.1016/J.Etap.2018.06.010 |
0.561 |
|
| 2018 |
Gadupudi GS, Elser BA, Sandgruber FA, Li X, Gibson-Corley KN, Robertson LW. PCB126 inhibits the activation of AMPK-CREB signal transduction required for energy sensing in liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29474705 DOI: 10.1093/Toxsci/Kfy041 |
0.822 |
|
| 2018 |
Parker VS, Squirewell EJ, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1. Environmental Toxicology and Pharmacology. 58: 196-201. PMID 29408762 DOI: 10.1016/J.Etap.2018.01.010 |
0.566 |
|
| 2018 |
Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environmental Science and Pollution Research International. PMID 29322390 DOI: 10.1007/S11356-017-1162-0 |
0.529 |
|
| 2018 |
Klenov V, Flor S, Ganesan S, Clark K, Eti N, Iqbal K, Soares M, Ludewig G, Keating A, Robertson L. Ovarian toxicity following exposure to polychlorinated biphenyl 126 is mediated by the aryl hydrocarbon receptor Fertility and Sterility. 110: e53. DOI: 10.1016/J.Fertnstert.2018.07.165 |
0.302 |
|
| 2017 |
Klaren WD, Vine D, Vogt S, Robertson LW. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environmental Science and Pollution Research International. PMID 28940161 DOI: 10.1007/S11356-017-0202-0 |
0.347 |
|
| 2017 |
Dhakal K, Gadupudi GS, Lehmler HJ, Ludewig G, Duffel MW, Robertson LW. Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environmental Science and Pollution Research International. PMID 28744683 DOI: 10.1007/S11356-017-9694-X |
0.803 |
|
| 2017 |
Gourronc FA, Robertson LW, Klingelhutz AJ. A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor. Environmental Science and Pollution Research International. PMID 28699004 DOI: 10.1007/S11356-017-9676-Z |
0.602 |
|
| 2016 |
Grimm FA, Lehmler HJ, Koh WX, DeWall J, Teesch LM, Hornbuckle KC, Thorne PS, Robertson LW, Duffel MW. Identification of a sulfate metabolite of PCB 11 in human serum. Environment International. PMID 27816204 DOI: 10.1016/J.Envint.2016.10.023 |
0.563 |
|
| 2016 |
Gadupudi GS, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis and glycogenolysis in PCB126 hepatotoxicity. Chemical Research in Toxicology. PMID 27509375 DOI: 10.1021/Acs.Chemrestox.6B00172 |
0.805 |
|
| 2016 |
Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) decreases hepatic and systemic ratios of epoxide to diol metabolites of unsaturated fatty acids in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27208083 DOI: 10.1093/Toxsci/Kfw084 |
0.62 |
|
| 2016 |
Rodriguez EA, Li X, Lehmler HJ, Robertson LW, Duffel MW. Sulfation of lower chlorinated polychlorinated biphenyls increases their affinity for the major drug-binding sites of human serum albumin. Environmental Science & Technology. PMID 27116425 DOI: 10.1021/Acs.Est.6B00484 |
0.527 |
|
| 2016 |
Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW. Assessment of the Mitigative Capacity of Dietary Zinc on PCB126 Hepatotoxicity and the Contribution of Zinc to Toxicity. Chemical Research in Toxicology. PMID 26967026 DOI: 10.1021/Acs.Chemrestox.6B00022 |
0.398 |
|
| 2016 |
Klaren WD, Flor S, Gibson-Corley KN, Ludewig G, Robertson LW. Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption. Toxicology Reports. 3: 21-28. PMID 26770886 DOI: 10.1016/J.Toxrep.2015.12.001 |
0.375 |
|
| 2016 |
Ekuase EJ, van 't Erve TJ, Rahaman A, Robertson LW, Duffel MW, Luthe G. Mechanistic insights into the specificity of human cytosolic sulfotransferase 2A1 (hSULT2A1) for hydroxylated polychlorinated biphenyls through the use of fluoro-tagged probes. Environmental Science and Pollution Research International. 23: 2119-27. PMID 26165989 DOI: 10.1007/S11356-015-4886-8 |
0.341 |
|
| 2015 |
Wang B, Klaren WD, Wels BR, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26660635 DOI: 10.1093/Toxsci/Kfv312 |
0.359 |
|
| 2015 |
Klaren WD, Gadupudi GS, Wels B, Simmons DL, Olivier AK, Robertson LW. Progression of micronutrient alteration and hepatotoxicity following acute PCB126 exposure. Toxicology. PMID 26410179 DOI: 10.1016/J.Tox.2015.09.004 |
0.807 |
|
| 2015 |
Wangpradit O, Adamcakova-Dodd A, Heitz K, Robertson L, Thorne PS, Luthe G. PAMAM dendrimers as nano carriers to investigate inflammatory responses induced by pulmonary exposure of PCB metabolites in Sprague-Dawley rats. Environmental Science and Pollution Research International. PMID 26400242 DOI: 10.1007/S11356-015-5022-5 |
0.799 |
|
| 2015 |
Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26396156 DOI: 10.1093/Toxsci/Kfv215 |
0.808 |
|
| 2015 |
Wangpradit O, Rahaman A, Mariappan SV, Buettner GR, Robertson LW, Luthe G. Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids. Environmental Science and Pollution Research International. PMID 26396011 DOI: 10.1007/S11356-015-5007-4 |
0.772 |
|
| 2015 |
Li M, Teesch LM, Murry DJ, Pope RM, Li Y, Robertson LW, Ludewig G. Cytochrome c adducts with PCB quinoid metabolites. Environmental Science and Pollution Research International. PMID 26062463 DOI: 10.1007/S11356-015-4801-3 |
0.313 |
|
| 2015 |
Grimm FA, He X, Teesch LM, Lehmler HJ, Robertson LW, Duffel MW. Tissue Distribution, Metabolism, and Excretion of 3,3'-Dichloro-4'-sulfooxy-biphenyl in the Rat. Environmental Science & Technology. 49: 8087-95. PMID 26046945 DOI: 10.1021/Acs.Est.5B01499 |
0.565 |
|
| 2015 |
Shen H, Robertson LW, Ludewig G. Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3. Environmental Science and Pollution Research International. PMID 26006071 DOI: 10.1007/S11356-015-4722-1 |
0.437 |
|
| 2015 |
Grimm FA, Hu D, Kania-Korwel I, Lehmler HJ, Ludewig G, Hornbuckle KC, Duffel MW, Bergman Å, Robertson LW. Metabolism and metabolites of polychlorinated biphenyls. Critical Reviews in Toxicology. 45: 245-72. PMID 25629923 DOI: 10.3109/10408444.2014.999365 |
0.532 |
|
| 2015 |
Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Modulating inhibitors of transthyretin fibrillogenesis via sulfation: polychlorinated biphenyl sulfates as models. Chemico-Biological Interactions. 228: 1-8. PMID 25595224 DOI: 10.1016/J.Cbi.2015.01.002 |
0.508 |
|
| 2015 |
Gadupudi G, Gourronc FA, Ludewig G, Robertson LW, Klingelhutz AJ. PCB126 inhibits adipogenesis of human preadipocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 132-41. PMID 25304490 DOI: 10.1016/J.Tiv.2014.09.015 |
0.784 |
|
| 2014 |
Aqil F, Shen H, Jeyabalan J, Xin X, Lehmler HJ, Ludewig G, Robertson LW, Gupta RC. Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants. Toxicology Reports. 1: 820-833. PMID 25530946 DOI: 10.1016/J.Toxrep.2014.09.010 |
0.576 |
|
| 2014 |
Dhakal K, Uwimana E, Adamcakova-Dodd A, Thorne PS, Lehmler HJ, Robertson LW. Disposition of phenolic and sulfated metabolites after inhalation exposure to 4-chlorobiphenyl (PCB3) in female rats. Chemical Research in Toxicology. 27: 1411-20. PMID 24988477 DOI: 10.1021/Tx500150H |
0.561 |
|
| 2014 |
Vorrink SU, Sarsour EH, Olivier AK, Robertson LW, Goswami PC, Domann FE. PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 377-82. PMID 24916446 DOI: 10.1016/J.Etp.2014.05.005 |
0.302 |
|
| 2014 |
Ekuase EJ, Lehmler HJ, Robertson LW, Duffel MW. Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1. Chemico-Biological Interactions. 212: 56-64. PMID 24508592 DOI: 10.1016/J.Cbi.2014.01.018 |
0.542 |
|
| 2014 |
Kim JS, Klösener J, Flor S, Peters TM, Ludewig G, Thorne PS, Robertson LW, Luthe G. Toxicity assessment of air-delivered particle-bound polybrominated diphenyl ethers. Toxicology. 317: 31-9. PMID 24451063 DOI: 10.1016/J.Tox.2014.01.005 |
0.304 |
|
| 2014 |
Shen H, Li M, Wang B, Lai IK, Robertson LW, Ludewig G. Dietary antioxidants (selenium and N-acetylcysteine) modulate paraoxonase 1 (PON1) in PCB 126-exposed rats. Environmental Science and Pollution Research International. 21: 6384-99. PMID 23644946 DOI: 10.1007/S11356-013-1690-1 |
0.813 |
|
| 2014 |
Salman KN, Stuart MA, Schmidt J, Borges T, McClain CJ, Robinson FR, Li M, Robertson LW. The effects of 3,3',4,4'-tetrabromobiphenyl on rats fed diets containing a constant level of copper and varying levels of molybdenum. Environmental Science and Pollution Research International. 21: 6400-9. PMID 23532536 DOI: 10.1007/S11356-013-1638-5 |
0.332 |
|
| 2013 |
Qin X, Lehmler HJ, Teesch LM, Robertson LW, Duffel MW. Chlorinated biphenyl quinones and phenyl-2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1. Chemical Research in Toxicology. 26: 1474-85. PMID 24059442 DOI: 10.1021/Tx400207Q |
0.585 |
|
| 2013 |
Zhu Y, Mapuskar KA, Marek RF, Xu W, Lehmler HJ, Robertson LW, Hornbuckle KC, Spitz DR, Aykin-Burns N. A new player in environmentally induced oxidative stress: polychlorinated biphenyl congener, 3,3'-dichlorobiphenyl (PCB11). Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 39-50. PMID 23997111 DOI: 10.1093/Toxsci/Kft186 |
0.583 |
|
| 2013 |
Dhakal K, Adamcakova-Dodd A, Lehmler HJ, Thorne PS, Robertson LW. Sulfate conjugates are urinary markers of inhalation exposure to 4-chlorobiphenyl (PCB3). Chemical Research in Toxicology. 26: 853-5. PMID 23713983 DOI: 10.1021/Tx4001539 |
0.558 |
|
| 2013 |
Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environmental Health Perspectives. 121: 657-62. PMID 23584369 DOI: 10.1289/Ehp.1206198 |
0.514 |
|
| 2013 |
Lai IK, Klaren WD, Li M, Wels B, Simmons DL, Olivier AK, Haschek WM, Wang K, Ludewig G, Robertson LW. Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver? Chemical Research in Toxicology. 26: 634-44. PMID 23527585 DOI: 10.1021/Tx400049S |
0.803 |
|
| 2013 |
Rignall B, Grote K, Gavrilov A, Weimer M, Kopp-Schneider A, Krause E, Appel KE, Buchmann A, Robertson LW, Lehmler HJ, Kania-Korwel I, Chahoud I, Schwarz M. Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 29-41. PMID 23457121 DOI: 10.1093/Toxsci/Kft034 |
0.569 |
|
| 2013 |
Ludewig G, Robertson LW. Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma. Cancer Letters. 334: 46-55. PMID 23211541 DOI: 10.1016/J.Canlet.2012.11.041 |
0.31 |
|
| 2012 |
Dhakal K, He X, Lehmler HJ, Teesch LM, Duffel MW, Robertson LW. Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats. Chemical Research in Toxicology. 25: 2796-804. PMID 23137097 DOI: 10.1021/Tx300416V |
0.593 |
|
| 2012 |
Lai IK, Dhakal K, Gadupudi GS, Li M, Ludewig G, Robertson LW, Olivier AK. N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents. Toxicology. 302: 25-33. PMID 22824115 DOI: 10.1016/J.Tox.2012.07.007 |
0.804 |
|
| 2012 |
Shen H, Robertson LW, Ludewig G. Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats. Toxicology Letters. 209: 291-8. PMID 22266287 DOI: 10.1016/J.Toxlet.2012.01.003 |
0.42 |
|
| 2011 |
Senthilkumar PK, Robertson LW, Ludewig G. PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK). Toxicology and Applied Pharmacology. 259: 115-23. PMID 22210444 DOI: 10.1016/J.Taap.2011.12.015 |
0.324 |
|
| 2011 |
Bunaciu RP, Tharappel JC, Lehmler HJ, Lee EY, Robertson LW, Bruckner GG, Spear BT, Glauert HP. Role of oil vehicle on hepatic cell proliferation in PCB-treated rats. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 30: 273-82. PMID 22181977 DOI: 10.1615/Jenvironpatholtoxicoloncol.V30.I4.10 |
0.518 |
|
| 2011 |
Wang B, Robertson LW, Wang K, Ludewig G. Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 1031-43. PMID 21970748 DOI: 10.3109/00498254.2011.603763 |
0.376 |
|
| 2011 |
Ekuase EJ, Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 24: 1720-8. PMID 21913674 DOI: 10.1021/Tx200260H |
0.561 |
|
| 2011 |
Lai IK, Chai Y, Simmons D, Watson WH, Tan R, Haschek WM, Wang K, Wang B, Ludewig G, Robertson LW. Dietary selenium as a modulator of PCB 126-induced hepatotoxicity in male Sprague-Dawley rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 202-14. PMID 21865291 DOI: 10.1093/Toxsci/Kfr215 |
0.816 |
|
| 2011 |
Song Y, Ambati J, Parkin S, Rankin SE, Robertson LW, Lehmler HJ. Crystal structure and density functional theory studies of toxic quinone metabolites of polychlorinated biphenyls. Chemosphere. 85: 386-92. PMID 21824639 DOI: 10.1016/J.Chemosphere.2011.07.004 |
0.546 |
|
| 2011 |
Senthilkumar PK, Klingelhutz AJ, Jacobus JA, Lehmler H, Robertson LW, Ludewig G. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicology Letters. 204: 64-70. PMID 21530622 DOI: 10.1016/J.Toxlet.2011.04.012 |
0.783 |
|
| 2011 |
Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1). Chemico-Biological Interactions. 189: 153-60. PMID 21130751 DOI: 10.1016/J.Cbi.2010.11.009 |
0.541 |
|
| 2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. 4'-Chloro-biphenyl-3-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o2306. PMID 21588655 DOI: 10.1107/S1600536810031338 |
0.495 |
|
| 2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. 3',4'-Dichloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o1615-6. PMID 21587847 DOI: 10.1107/S1600536810020362 |
0.424 |
|
| 2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. Biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o1073. PMID 21579128 DOI: 10.1107/S1600536810012845 |
0.498 |
|
| 2010 |
Wangpradit O, Moman E, Nolan KB, Buettner GR, Robertson LW, Luthe G. Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2. Chemosphere. 81: 1501-8. PMID 20843536 DOI: 10.1016/J.Chemosphere.2010.08.041 |
0.782 |
|
| 2010 |
Jacobus JA, Wang B, Maddox C, Esch H, Lehmann L, Robertson LW, Wang K, Kirby P, Ludewig G. 3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats. Environment International. 36: 970-9. PMID 20739065 DOI: 10.1016/J.Envint.2010.07.006 |
0.784 |
|
| 2010 |
van 't Erve TJ, Rautiainen RH, Robertson LW, Luthe G. Trimethylsilyldiazomethane: A safe non-explosive, cost effective and less-toxic reagent for phenol derivatization in GC applications Environment International. 36: 835-842. PMID 20385409 DOI: 10.1016/J.Envint.2010.02.011 |
0.324 |
|
| 2010 |
Xie W, Wang K, Robertson LW, Ludewig G. Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites. Environment International. 36: 950-61. PMID 20129669 DOI: 10.1016/J.Envint.2009.12.004 |
0.362 |
|
| 2010 |
Lai I, Chai Y, Simmons D, Luthe G, Coleman MC, Spitz D, Haschek WM, Ludewig G, Robertson LW. Acute toxicity of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) in male Sprague-Dawley rats: effects on hepatic oxidative stress, glutathione and metals status. Environment International. 36: 918-23. PMID 19969354 DOI: 10.1016/J.Envint.2009.11.002 |
0.814 |
|
| 2010 |
Chan K, Lehmler HJ, Sivagnanam M, Feng CY, Robertson L, O'Brien PJ. Cytotoxic effects of polychlorinated biphenyl hydroquinone metabolites in rat hepatocytes. Journal of Applied Toxicology : Jat. 30: 163-71. PMID 19830680 DOI: 10.1002/Jat.1483 |
0.598 |
|
| 2010 |
Ravoori S, Srinivasan C, Pereg D, Robertson LW, Ayotte P, Gupta RC. Protective effects of selenium against DNA adduct formation in Inuit environmentally exposed to PCBs. Environment International. 36: 980-6. PMID 19735942 DOI: 10.1016/J.Envint.2009.08.001 |
0.331 |
|
| 2010 |
Zhao HX, Adamcakova-Dodd A, Hu D, Hornbuckle KC, Just CL, Robertson LW, Thorne PS, Lehmler HJ. Development of a synthetic PCB mixture resembling the average polychlorinated biphenyl profile in Chicago air Environment International. 36: 819-827. PMID 19375801 DOI: 10.1016/J.Envint.2009.03.003 |
0.303 |
|
| 2010 |
Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. An efficient approach to sulfate metabolites of polychlorinated biphenyls. Environment International. 36: 843-8. PMID 19345419 DOI: 10.1016/J.Envint.2009.02.005 |
0.555 |
|
| 2010 |
Telu S, Parkin S, Robertson LW, Lehmler HJ. Improved syntheses of non-dioxin-like polychlorinated biphenyls (PCBs) and some of their sulfur-containing metabolites. Environment International. 36: 828-34. PMID 19261331 DOI: 10.1016/J.Envint.2009.01.013 |
0.526 |
|
| 2009 |
Zhu Y, Kalen AL, Li L, Lehmler HJ, Robertson LW, Goswami PC, Spitz DR, Aykin-Burns N. Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radical Biology & Medicine. 47: 1762-71. PMID 19796678 DOI: 10.1016/J.Freeradbiomed.2009.09.024 |
0.36 |
|
| 2009 |
Dreiem A, Rykken S, Lehmler HJ, Robertson LW, Fonnum F. Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells. Toxicology and Applied Pharmacology. 240: 306-13. PMID 19631230 DOI: 10.1016/J.Taap.2009.07.016 |
0.558 |
|
| 2009 |
Li X, Robertson LW, Lehmler HJ. Electron ionization mass spectral fragmentation study of sulfation derivatives of polychlorinated biphenyls. Chemistry Central Journal. 3: 5. PMID 19272150 DOI: 10.1186/1752-153X-3-5 |
0.52 |
|
| 2009 |
Spencer WA, Lehmler HJ, Robertson LW, Gupta RC. Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species. Free Radical Biology & Medicine. 46: 1346-52. PMID 19233261 DOI: 10.1016/J.Freeradbiomed.2009.02.005 |
0.539 |
|
| 2009 |
Liu Y, Smart JT, Song Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1065-72. PMID 19196841 DOI: 10.1124/Dmd.108.026021 |
0.58 |
|
| 2009 |
Wangpradit O, Teesch LM, Mariappan SV, Duffel MW, Norstrom K, Robertson LW, Luthe G. Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase. Chemical Research in Toxicology. 22: 64-71. PMID 19105592 DOI: 10.1021/Tx800300T |
0.788 |
|
| 2009 |
Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chemical Research in Toxicology. 22: 201-7. PMID 18954145 DOI: 10.1021/Tx800328U |
0.532 |
|
| 2008 |
Ravoori S, Ayotte P, Srinivasan C, Pereg D, Robertson LW, Russell GK, Jeyabalan J, Gupta RC. DNA damage associated with PCBs in the whole blood cells of Inuit. Environmental Toxicology and Pharmacology. 25: 273-6. PMID 21783863 DOI: 10.1016/J.Etap.2007.10.027 |
0.319 |
|
| 2008 |
Robertson LW, Sulkowski W, Hennig B. Preface. Environmental Toxicology and Pharmacology. 25: 127. PMID 21783846 DOI: 10.1016/j.etap.2007.10.006 |
0.392 |
|
| 2008 |
Li X, Parkin S, Robertson LW, Lehmler HJ. 4'-Chloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 64: o2464. PMID 21581432 DOI: 10.1107/S1600536808038865 |
0.431 |
|
| 2008 |
Telu S, Parkin S, Robertson LW, Lehmler HJ. 1,3,5-Trichloro-2-methoxy-benzene. Acta Crystallographica. Section E, Structure Reports Online. 64: o424. PMID 21201451 DOI: 10.1107/S160053680800055X |
0.49 |
|
| 2008 |
Luthe G, Jacobus JA, Robertson LW. Receptor interactions by polybrominated diphenyl ethers versus polychlorinated biphenyls: a theoretical Structure-activity assessment. Environmental Toxicology and Pharmacology. 25: 202-10. PMID 19768137 DOI: 10.1016/J.Etap.2007.10.017 |
0.755 |
|
| 2008 |
Glauert HP, Tharappel JC, Lu Z, Stemm D, Banerjee S, Chan LS, Lee EY, Lehmler HJ, Robertson LW, Spear BT. Role of oxidative stress in the promoting activities of pcbs. Environmental Toxicology and Pharmacology. 25: 247-50. PMID 19122744 DOI: 10.1016/J.Etap.2007.10.025 |
0.564 |
|
| 2008 |
Song Y, Buettner GR, Parkin S, Wagner BA, Robertson LW, Lehmler HJ. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones. The Journal of Organic Chemistry. 73: 8296-304. PMID 18839991 DOI: 10.1021/Jo801397G |
0.554 |
|
| 2008 |
Tharappel JC, Lehmler HJ, Srinivasan C, Robertson LW, Spear BT, Glauert HP. Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 3467-74. PMID 18796325 DOI: 10.1016/J.Fct.2008.08.023 |
0.601 |
|
| 2008 |
Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radical Biology & Medicine. 45: 1094-102. PMID 18691649 DOI: 10.1016/J.Freeradbiomed.2008.07.007 |
0.553 |
|
| 2008 |
Glauert HP, Tharappel JC, Banerjee S, Chan NL, Kania-Korwel I, Lehmler HJ, Lee EY, Robertson LW, Spear BT. Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice. Toxicology and Applied Pharmacology. 232: 302-8. PMID 18644402 DOI: 10.1016/J.Taap.2008.06.013 |
0.515 |
|
| 2008 |
Ludewig G, Lehmann L, Esch H, Robertson LW. Metabolic Activation of PCBs to Carcinogens in Vivo - A Review. Environmental Toxicology and Pharmacology. 25: 241-6. PMID 18452002 DOI: 10.1016/J.Etap.2007.10.029 |
0.454 |
|
| 2008 |
Jacobus JA, Flor S, Klingelhutz A, Robertson LW, Ludewig G. 2-(4'-CHLOROPHENYL)-1,4-BENZOQUINONE INCREASES THE FREQUENCY OF MICRONUCLEI AND SHORTENS TELOMERES. Environmental Toxicology and Pharmacology. 25: 267-272. PMID 18438462 DOI: 10.1016/J.Etap.2007.10.022 |
0.785 |
|
| 2008 |
Kania-Korwel I, Xie W, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes. Archives of Environmental Contamination and Toxicology. 55: 510-7. PMID 18437444 DOI: 10.1007/S00244-007-9111-4 |
0.562 |
|
| 2008 |
Luthe G, Garcia Boy R, Jacobus J, Smith BJ, Rahaman A, Robertson LW, Ludewig G. Xenobiotic geometry and media pH determine cytotoxicity through solubility. Chemical Research in Toxicology. 21: 1017-27. PMID 18402468 DOI: 10.1021/Tx700214P |
0.761 |
|
| 2008 |
Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler HJ. Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice. Environmental Toxicology and Chemistry / Setac. 27: 299-305. PMID 18348647 DOI: 10.1897/07-359R.1 |
0.549 |
|
| 2008 |
Stemm DN, Tharappel JC, Lehmler HJ, Srinivasan C, Morris JS, Spate VL, Robertson LW, Spear BT, Glauert HP. Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl. Experimental Biology and Medicine (Maywood, N.J.). 233: 366-76. PMID 18296742 DOI: 10.3181/0708-Rm-211 |
0.604 |
|
| 2008 |
Sacco JC, Lehmler HJ, Robertson LW, Li W, James MO. Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 623-30. PMID 18180271 DOI: 10.1124/Dmd.107.019596 |
0.544 |
|
| 2007 |
Robertson LW, Berberian I, Borges T, Chen LC, Chow CK, Glauert HP, Filser JG, Thomas H. Suppression of peroxisomal enzyme activities and cytochrome P450 4A isozyme expression by congeneric polybrominated and polychlorinated biphenyls. Ppar Research. 2007: 15481. PMID 18274624 DOI: 10.1155/2007/15481 |
0.414 |
|
| 2007 |
Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler HJ. Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 637-44. PMID 17950514 DOI: 10.1016/J.Fct.2007.09.072 |
0.345 |
|
| 2007 |
Bunaciu RP, Tharappel JC, Lehmler HJ, Kania-Korwel I, Robertson LW, Srinivasan C, Spear BT, Glauert HP. The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats. Toxicology. 239: 147-55. PMID 17703865 DOI: 10.1016/J.Tox.2007.06.102 |
0.609 |
|
| 2007 |
Zettner MA, Flor S, Ludewig G, Wagner J, Robertson LW, Lehmann L. Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 88-98. PMID 17686921 DOI: 10.1093/Toxsci/Kfm204 |
0.342 |
|
| 2007 |
Sadeghi-Aliabadi H, Chan K, Lehmler HJ, Robertson LW, O'Brien PJ. Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. Chemico-Biological Interactions. 167: 184-92. PMID 17408604 DOI: 10.1016/J.Cbi.2007.02.011 |
0.587 |
|
| 2007 |
Kania-Korwel I, Shaikh NS, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration. Chirality. 19: 56-66. PMID 17089340 DOI: 10.1002/Chir.20342 |
0.539 |
|
| 2007 |
Lehmann L, Esch HL, Kirby PA, Robertson LW, Ludewig G. 4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats. Carcinogenesis. 28: 471-8. PMID 16950798 DOI: 10.1093/Carcin/Bgl157 |
0.378 |
|
| 2006 |
Liu Y, Apak TI, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 19: 1420-5. PMID 17112228 DOI: 10.1021/TX060160+ |
0.552 |
|
| 2006 |
Ptak A, Ludewig G, Kapiszewska M, Magnowska Z, Lehmler HJ, Robertson LW, Gregoraszczuk EL. Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. Toxicology Letters. 166: 200-11. PMID 16949219 DOI: 10.1016/J.Toxlet.2006.07.304 |
0.59 |
|
| 2006 |
Bender RP, Lehmler HJ, Robertson LW, Ludewig G, Osheroff N. Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate. Biochemistry. 45: 10140-52. PMID 16906772 DOI: 10.1021/Bi0524666 |
0.372 |
|
| 2006 |
Kania-Korwel I, Garrison AW, Avants JK, Hornbuckle KC, Robertson LW, Sulkowski WW, Lehmler HJ. Distribution of chiral PCBs in selected tissues in the laboratory rat. Environmental Science & Technology. 40: 3704-10. PMID 16830530 DOI: 10.1021/Es0602086 |
0.548 |
|
| 2006 |
Kunz S, Schwarz M, Schilling B, Päpke O, Lehmler HJ, Robertson LW, Schrenk D, Schmitz HJ. Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicology Letters. 164: 133-43. PMID 16426774 DOI: 10.1016/J.Toxlet.2005.12.003 |
0.582 |
|
| 2006 |
Wang LQ, Lehmler HJ, Robertson LW, James MO. Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate. Chemico-Biological Interactions. 159: 235-46. PMID 16413005 DOI: 10.1016/J.Cbi.2005.12.004 |
0.542 |
|
| 2006 |
Ptak A, Ludewig G, Robertson L, Lehmler HJ, Gregoraszczuk EL. In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity. Toxicology Letters. 164: 113-22. PMID 16412591 DOI: 10.1016/J.Toxlet.2005.12.001 |
0.581 |
|
| 2006 |
Vyas SM, Parkin S, Robertson LW, Lehmler H. 2,5-Dichloro-4′-methoxybiphenyl Acta Crystallographica Section E Structure Reports Online. 62: o4162-o4163. DOI: 10.1107/S1600536806033319 |
0.479 |
|
| 2006 |
Vyas SM, Parkin S, Robertson LW, Lehmler H. 4-Chloro-2′,3′-dimethoxybiphenyl Acta Crystallographica Section E Structure Reports Online. 62: o3639-o3640. DOI: 10.1107/S1600536806028923 |
0.476 |
|
| 2005 |
Kodavanti PRS, Ward TR, Ludewig G, Robertson LW, Birnbaum LS. Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships Toxicological Sciences. 88: 181-192. PMID 16107548 DOI: 10.1093/Toxsci/Kfi289 |
0.328 |
|
| 2005 |
Kania-Korwel I, Hornbuckle KC, Peck A, Ludewig G, Robertson LW, Sulkowski WW, Espandiari P, Gairola CG, Lehmler HJ. Congener-specific tissue distribution of aroclor 1254 and a highly chlorinated environmental PCB mixture in rats. Environmental Science & Technology. 39: 3513-20. PMID 15954224 DOI: 10.1021/Es047987F |
0.535 |
|
| 2005 |
Wang LQ, Lehmler HJ, Robertson LW, Falany CN, James MO. In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols. Environmental Health Perspectives. 113: 680-7. PMID 15929889 DOI: 10.1289/Ehp.7837 |
0.551 |
|
| 2005 |
Ptak A, Ludewig G, Lehmler HJ, Wójtowicz AK, Robertson LW, Gregoraszczuk EL. Comparison of the actions of 4-chlorobiphenyl and its hydroxylated metabolites on estradiol secretion by ovarian follicles in primary cells in culture. Reproductive Toxicology (Elmsford, N.Y.). 20: 57-64. PMID 15808786 DOI: 10.1016/J.Reprotox.2004.12.003 |
0.547 |
|
| 2005 |
Lehmler HJ, Robertson LW, Garrison AW, Kodavanti PR. Effects of PCB 84 enantiomers on [3H]-phorbol ester binding in rat cerebellar granule cells and 45Ca2+-uptake in rat cerebellum. Toxicology Letters. 156: 391-400. PMID 15763638 DOI: 10.1016/J.Toxlet.2004.12.011 |
0.543 |
|
| 2005 |
Glauert HP, Lu Z, Kumar A, Bunaciu RP, Patel S, Tharappel JC, Stemm DN, Lehmler HJ, Lee EY, Robertson LW, Spear BT. Dietary vitamin E does not inhibit the promotion of liver carcinogenesis by polychlorinated biphenyls in rats. The Journal of Nutrition. 135: 283-6. PMID 15671227 DOI: 10.1093/Jn/135.2.283 |
0.566 |
|
| 2005 |
Hennig B, Reiterer G, Toborek M, Matveev SV, Daugherty A, Smart E, Robertson LW. Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor. Environmental Health Perspectives. 113: 83-7. PMID 15626652 DOI: 10.1289/Ehp.7280 |
0.562 |
|
| 2005 |
Espandiari P, Robertson LW, Srinivasan C, Glauert HP. Comparison of different initiation protocols in the resistant hepatocyte model. Toxicology. 206: 373-81. PMID 15588927 DOI: 10.1016/J.Tox.2004.07.014 |
0.322 |
|
| 2005 |
Hansen L, Machala M, Fischer L, James M, Hennig B, Glauert H, Narbonne JF, Van Bree L, Schultz T, Grevatt P, Suk W, Holoubek I, Robertson L. Research needs identified at the Second PCB Workshop in Brno, Czech Republic, May 7-11, 2002 Toxicological and Environmental Chemistry. 87: 261-265. DOI: 10.1080/02772240500079011 |
0.516 |
|
| 2004 |
Kania-Korwel I, Parkin S, Robertson LW, Lehmler HJ. Synthesis of polychlorinated biphenyls and their metabolites with a modified Suzuki-coupling. Chemosphere. 56: 735-44. PMID 15251288 DOI: 10.1016/J.Chemosphere.2004.04.035 |
0.495 |
|
| 2004 |
Lu Z, Lee EY, Robertson LW, Glauert HP, Spear BT. Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-kappaB. Toxicological Sciences : An Official Journal of the Society of Toxicology. 81: 35-42. PMID 15201435 DOI: 10.1093/Toxsci/Kfh193 |
0.327 |
|
| 2004 |
Gauger KJ, Kato Y, Haraguchi K, Lehmler HJ, Robertson LW, Bansal R, Zoeller RT. Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors. Environmental Health Perspectives. 112: 516-23. PMID 15064154 DOI: 10.1289/Ehp.6672 |
0.549 |
|
| 2004 |
Machala M, Bláha L, Lehmler HJ, Plísková M, Májková Z, Kapplová P, Sovadinová I, Vondrácek J, Malmberg T, Robertson LW. Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells. Chemical Research in Toxicology. 17: 340-7. PMID 15025504 DOI: 10.1021/Tx030034V |
0.594 |
|
| 2004 |
Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW. Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 41-6. PMID 14976334 DOI: 10.1093/Toxsci/Kfh097 |
0.619 |
|
| 2004 |
Kania-Korwel I, Parkin S, Robertson LW, Lehmler H. 2,4,5-Trichlorobiphenyl Acta Crystallographica Section E Structure Reports Online. 60: o1652-o1653. DOI: 10.1107/S1600536804020975 |
0.476 |
|
| 2003 |
Ramadass P, Meerarani P, Toborek M, Robertson LW, Hennig B. Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 212-9. PMID 12970578 DOI: 10.1093/Toxsci/Kfg227 |
0.582 |
|
| 2003 |
Lu Z, Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. Effect of a single dose of polychlorinated biphenyls on hepatic cell proliferation and the DNA binding activity of NF-kappaB and AP-1 in rats. Molecular Carcinogenesis. 37: 171-80. PMID 12891626 DOI: 10.1002/Mc.10135 |
0.405 |
|
| 2003 |
Choi W, Eum SY, Lee YW, Hennig B, Robertson LW, Toborek M. PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 75: 47-56. PMID 12805654 DOI: 10.1093/Toxsci/Kfg149 |
0.55 |
|
| 2003 |
Tampal N, Myers S, Robertson LW. Binding of polychlorinated biphenyls/metabolites to hemoglobin. Toxicology Letters. 142: 53-60. PMID 12765239 DOI: 10.1016/S0378-4274(02)00484-8 |
0.359 |
|
| 2003 |
Lee YW, Park HJ, Son KW, Hennig B, Robertson LW, Toborek M. 2,2',4,6,6'-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicology and Applied Pharmacology. 189: 1-10. PMID 12758055 DOI: 10.1016/S0041-008X(03)00084-X |
0.569 |
|
| 2003 |
Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW. Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model. Toxicology and Applied Pharmacology. 186: 55-62. PMID 12583993 DOI: 10.1016/S0041-008X(02)00018-2 |
0.598 |
|
| 2003 |
Arif JM, Lehmler HJ, Robertson LW, Gupta RC. Interaction of benzoquinone- and hydroquinone-derivatives of lower chlorinated biphenyls with DNA and nucleotides in vitro. Chemico-Biological Interactions. 142: 307-16. PMID 12453668 DOI: 10.1016/S0009-2797(02)00141-2 |
0.506 |
|
| 2003 |
Kania-Korwel I, Robertson LW, Lehmler H, Parkin S. 2,4,6-Trichloroiodobenzene Acta Crystallographica Section E Structure Reports Online. 59: o1770-o1771. DOI: 10.1107/S1600536803022530 |
0.459 |
|
| 2003 |
Kania-Korwel I, Lehmler H, Robertson LW, Parkin S. 2,4,5-Trichloro-1-iodobenzene Acta Crystallographica Section E Structure Reports Online. 59: o1048-o1049. DOI: 10.1107/S1600536803013977 |
0.474 |
|
| 2002 |
Tampal N, Lehmler HJ, Espandiari P, Malmberg T, Robertson LW. Glucuronidation of hydroxylated polychlorinated biphenyls (PCBs). Chemical Research in Toxicology. 15: 1259-66. PMID 12387623 DOI: 10.1021/Tx0200212 |
0.581 |
|
| 2002 |
Hennig B, Meerarani P, Slim R, Toborek M, Daugherty A, Silverstone AE, Robertson LW. Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicology and Applied Pharmacology. 181: 174-83. PMID 12079426 DOI: 10.1006/Taap.2002.9408 |
0.58 |
|
| 2002 |
Fadhel Z, Lu Z, Robertson LW, Glauert HP. Effect of 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl on the induction of hepatic lipid peroxidation and cytochrome P-450 associated enzyme activities in rats. Toxicology. 175: 15-25. PMID 12049832 DOI: 10.1016/S0300-483X(02)00086-0 |
0.461 |
|
| 2002 |
Hennig B, Hammock BD, Slim R, Toborek M, Saraswathi V, Robertson LW. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. International Journal of Hygiene and Environmental Health. 205: 95-102. PMID 12018021 DOI: 10.1078/1438-4639-00134 |
0.569 |
|
| 2002 |
Srinivasan A, Robertson LW, Ludewig G. Sulfhydryl binding and topoisomerase inhibition by PCB metabolites. Chemical Research in Toxicology. 15: 497-505. PMID 11952335 DOI: 10.1021/TX010128+ |
0.386 |
|
| 2002 |
Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls. Toxicology and Applied Pharmacology. 179: 172-84. PMID 11906247 DOI: 10.1006/Taap.2001.9360 |
0.414 |
|
| 2002 |
Lehmler HJ, Parkin S, Robertson LW. The three-dimensional structure of 3, 3', 5'-trichloro-4-methoxybiphenyl, a "coplanar" polychlorinated biphenyl (PCB) derivative. Chemosphere. 46: 485-8. PMID 11829405 DOI: 10.1016/S0045-6535(01)00177-1 |
0.485 |
|
| 2002 |
Pereg D, Robertson LW, Gupta RC. DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites. Chemico-Biological Interactions. 139: 129-44. PMID 11823002 DOI: 10.1016/S0009-2797(01)00292-7 |
0.377 |
|
| 2002 |
Lehmler HJ, Robertson LW, Parkin S, Brock CP. Z' = 4 structure without obvious pseudosymmetry: implications for the formation of solid-state compounds. Acta Crystallographica. Section B, Structural Science. 58: 140-7. PMID 11818662 DOI: 10.1107/S0108768101018043 |
0.486 |
|
| 2002 |
Lehmler HJ, Robertson LW. Synthesis of hydroxylated PCB metabolites with the Suzuki-coupling. Chemosphere. 45: 1119-27. PMID 11695625 DOI: 10.1016/S0045-6535(01)00052-2 |
0.511 |
|
| 2002 |
Lehmler HJ, Robertson LW. Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-coupling. Chemosphere. 45: 137-43. PMID 11572605 DOI: 10.1016/S0045-6535(00)00546-4 |
0.479 |
|
| 2002 |
Lehmler H, Robertson LW, Parkin S. 2-(3,5-Dichlorophenyl)-1,4-benzoquinone Acta Crystallographica Section E Structure Reports Online. 58: o366-o367. DOI: 10.1107/S160053680200291X |
0.472 |
|
| 2001 |
Pereg D, Tampal N, Espandiari P, Robertson LW. Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice. Chemico-Biological Interactions. 137: 243-58. PMID 11566292 DOI: 10.1016/S0009-2797(01)00256-3 |
0.347 |
|
| 2001 |
Twaroski TP, O'Brien ML, Robertson LW. Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress. Biochemical Pharmacology. 62: 273-81. PMID 11434900 DOI: 10.1016/S0006-2952(01)00668-2 |
0.462 |
|
| 2001 |
Slim R, Hammock BD, Toborek M, Robertson LW, Newman JW, Morisseau CH, Watkins BA, Saraswathi V, Hennig B. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicology and Applied Pharmacology. 171: 184-93. PMID 11243918 DOI: 10.1006/Taap.2001.9131 |
0.564 |
|
| 2001 |
Srinivasan A, Lehmler HJ, Robertson LW, Ludewig G. Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites. Toxicological Sciences : An Official Journal of the Society of Toxicology. 60: 92-102. PMID 11222876 DOI: 10.1093/Toxsci/60.1.92 |
0.555 |
|
| 2001 |
Twaroski TP, O'Brien ML, Larmonier N, Glauert HP, Robertson LW. Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver. Toxicology and Applied Pharmacology. 171: 85-93. PMID 11222084 DOI: 10.1006/Taap.2000.9114 |
0.435 |
|
| 2001 |
Lehmler H, Robertson LW, Parkin S. 4-Chloro-3′,4′-dihydroxybiphenyl Acta Crystallographica Section E Structure Reports Online. 57: o590-o591. DOI: 10.1107/S1600536801008844 |
0.488 |
|
| 2001 |
Lehmler H, Parkin S, Robertson LW. 2,3,4′-Trichlorobiphenyl Acta Crystallographica Section E Structure Reports Online. 57: o111-o112. DOI: 10.1107/S1600536800021127 |
0.465 |
|
| 2000 |
Slim R, Toborek M, Robertson LW, Lehmler HJ, Hennig B. Cellular glutathione status modulates polychlorinated biphenyl-induced stress response and apoptosis in vascular endothelial cells. Toxicology and Applied Pharmacology. 166: 36-42. PMID 10873716 DOI: 10.1006/Taap.2000.8944 |
0.571 |
|
| 2000 |
McLean MR, Twaroski TP, Robertson LW. Redox cycling of 2-(x'-mono, -di, -trichlorophenyl)- 1, 4-benzoquinones, oxidation products of polychlorinated biphenyls. Archives of Biochemistry and Biophysics. 376: 449-55. PMID 10775433 DOI: 10.1006/Abbi.2000.1754 |
0.365 |
|
| 2000 |
Slim R, Toborek M, Robertson LW, Hennig B. Antioxidant protection against PCB-mediated endothelial cell activation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 52: 232-9. PMID 10630576 DOI: 10.1093/Toxsci/52.2.232 |
0.542 |
|
| 1999 |
Hennig B, Slim R, Toborek M, Robertson LW. Linoleic acid amplifies polychlorinated biphenyl-mediated dysfunction of endothelial cells. Journal of Biochemical and Molecular Toxicology. 13: 83-91. PMID 9890193 DOI: 10.1002/(Sici)1099-0461(1999)13:2<83::Aid-Jbt4>3.0.Co;2-7 |
0.576 |
|
| 1999 |
Espandiari P, Glauert HP, Lee EY, Robertson LW. Promoting activity of the herbicide dicamba (2-methoxy-3, 6-dichlorobenzoic acid) in two stage hepatocarcinogenesis. International Journal of Oncology. 14: 79-84. DOI: 10.3892/Ijo.14.1.79 |
0.354 |
|
| 1997 |
Oakley GG, Devanaboyina U, Robertson LW, Gupta RC. Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer. Chemical Research in Toxicology. 9: 1285-92. PMID 8951230 DOI: 10.1021/Tx960103O |
0.318 |
|
| 1996 |
McLean MR, Robertson LW, Gupta RC. Detection of PCB adducts by the 32P-postlabeling technique. Chemical Research in Toxicology. 9: 165-71. PMID 8924587 DOI: 10.1021/Tx9500843 |
0.353 |
|
| 1996 |
McLean MR, Bauer U, Amaro AR, Robertson LW. Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl. Chemical Research in Toxicology. 9: 158-64. PMID 8924585 DOI: 10.1021/Tx950083A |
0.411 |
|
| 1996 |
Amaro AR, Oakley GG, Bauer U, Spielmann HP, Robertson LW. Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase. Chemical Research in Toxicology. 9: 623-9. PMID 8728508 DOI: 10.1021/Tx950117E |
0.313 |
|
| 1996 |
Oakley GG, Robertson LW, Gupta RC. Analysis of polychlorinated biphenyl-DNA adducts by 32P-postlabeling. Carcinogenesis. 17: 109-14. PMID 8565118 DOI: 10.1093/Carcin/17.1.109 |
0.352 |
|
| 1996 |
Wilson MW, Lay LT, Chow CK, Tai HH, Robertson LW, Glauert HP. Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid. Archives of Toxicology. 69: 491-7. PMID 8526745 DOI: 10.1007/S002040050203 |
0.429 |
|
| 1995 |
Toborek M, Barger SW, Mattson MP, Espandiari P, Robertson LW, Hennig B. Exposure to polychlorinated biphenyls causes endothelial cell dysfunction. Journal of Biochemical Toxicology. 10: 219-26. PMID 8568836 DOI: 10.1002/Jbt.2570100406 |
0.573 |
|
| 1995 |
Chen H, Huang CY, Wilson MW, Lay LT, Robertson LW, Chow CK, Glauert HP. Effect of the peroxisome proliferators ciprofibrate and perfluorodecanoic acid on hepatic cell proliferation and toxicity in Sprague-Dawley rats. Carcinogenesis. 15: 2847-50. PMID 8001245 DOI: 10.1093/Carcin/15.12.2847 |
0.397 |
|
| 1995 |
Berberian I, Chen LC, Robinson FR, Glauert HP, Chow CK, Robertson LW. Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl in rats initiated with diethylnitrosamine. Carcinogenesis. 16: 393-8. PMID 7859372 DOI: 10.1093/Carcin/16.2.393 |
0.391 |
|
| 1995 |
Huang CY, Wilson MW, Lay LT, Chow CK, Robertson LW, Glauert HP. Increased 8-hydroxydeoxyguanosine in hepatic DNA of rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid. Cancer Letters. 87: 223-8. PMID 7812944 DOI: 10.1016/0304-3835(94)90226-7 |
0.382 |
|
| 1995 |
Bauer U, Amaro AR, Robertson LW. A new strategy for the synthesis of polychlorinated biphenyl metabolites. Chemical Research in Toxicology. 8: 92-5. PMID 7703372 DOI: 10.1021/Tx00043A012 |
0.303 |
|
| 1995 |
Espandiari P, Thomas VA, Glauert HP, O'Brien M, Noonan D, Robertson LW. The herbicide dicamba (2-methoxy-3,6-dichlorobenzoic acid) is a peroxisome proliferator in rats. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 26: 85-90. PMID 7657066 DOI: 10.1006/Faat.1995.1077 |
0.424 |
|
| 1994 |
Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A, Blouin RA. Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment. Archives of Biochemistry and Biophysics. 307: 386-90. PMID 8274026 DOI: 10.1006/Abbi.1993.1604 |
0.622 |
|
| 1994 |
Tuntaterdtum S, Chaudhary IP, Cibull M, Robertson LW, Blouin RA. Acetaminophen hepatotoxicity: influence of phenobarbital and beta-naphthoflavone treatment in obese and lean Zucker rats. Toxicology and Applied Pharmacology. 123: 219-25. PMID 8248929 DOI: 10.1006/Taap.1993.1240 |
0.359 |
|
| 1994 |
Bani MH, Narbonne JF, Fukuhara M, Ushio F, Robertson LW. Differential modulation of hepatic cytochrome P-450 enzymes in rat and Syrian hamster by 4'-trifluoromethyl-2,3,4,5-tetrachlorobiphenyl J.Biochem.Toxicol.. 9: 241-248. PMID 7853359 DOI: 10.1002/Jbt.2570090504 |
0.348 |
|
| 1994 |
Chen L, Berberian I, Glauert HP, Robertson LW, Chow CK. Altered Tissue Levels of Vitamin a by Selected Polycyclic Aromatic Hydrocarbons (PAHs) Polycyclic Aromatic Compounds. 4: 173-182. DOI: 10.1080/10406639408014701 |
0.385 |
|
| 1993 |
Blouin RA, Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A. Cytochrome P450 2B enzyme (CYP2B) induction defect following phenobarbital treatment in the fa/fa Zucker rat: molecular characterization. Archives of Biochemistry and Biophysics. 303: 313-20. PMID 8512318 DOI: 10.1006/Abbi.1993.1289 |
0.613 |
|
| 1993 |
Borges T, Glauert HP, Robertson LW. Perfluorodecanoic acid noncompetitively inhibits the peroxisomal enzymes enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase. Toxicology and Applied Pharmacology. 118: 8-15. PMID 8430427 DOI: 10.1006/Taap.1993.1003 |
0.366 |
|
| 1993 |
Borges T, Peterson RE, Pitot HC, Robertson LW, Glauert HP. Effect of the peroxisome proliferator perfluorodecanoic acid on the promotion of two-stage hepatocarcinogenesis in rats. Cancer Letters. 72: 111-20. PMID 8104684 DOI: 10.1016/0304-3835(93)90019-6 |
0.393 |
|
| 1992 |
Buchmann A, Ziegler S, Wolf A, Robertson LW, Durham SK, Schwarz M. Effects of polychlorinated biphenyls in rat liver: correlation between primary subcellular effects and promoting activity. Toxicology and Applied Pharmacology. 111: 454-68. PMID 1684070 DOI: 10.1016/0041-008X(91)90250-I |
0.431 |
|
| 1992 |
Borges T, Robertson LW, Peterson RE, Glauert HP. Dose-related effects of perfluorodecanoic acid on growth, feed intake and hepatic peroxisomal beta-oxidation. Archives of Toxicology. 66: 18-22. PMID 1580792 DOI: 10.1007/Bf02307265 |
0.371 |
|
| 1992 |
Glauert HP, Srinivasan S, Tatum VL, Chen LC, Saxon DM, Lay LT, Borges T, Baker M, Chen LH, Robertson LW. Effects of the peroxisome proliferators ciprofibrate and perfluorodecanoic acid on hepatic cellular antioxidants and lipid peroxidation in rats. Biochemical Pharmacology. 43: 1353-9. PMID 1562286 DOI: 10.1016/0006-2952(92)90513-I |
0.415 |
|
| 1992 |
Pélissier MA, Siess MH, Lhuissier M, Grolier P, Suschetet M, Narbonne JF, Albrecht R, Robertson LW. Effect of prototypic polychlorinated biphenyls on hepatic and renal vitamin contents and on drug-metabolizing enzymes in rats fed diets containing low or high levels of retinyl palmitate Food and Chemical Toxicology. 30: 723-729. PMID 1398354 DOI: 10.1016/0278-6915(92)90170-P |
0.36 |
|
| 1992 |
Glatt H, Anklam E, Robertson LW. Biphenyl and fluorinated derivatives: liver enzyme-mediated mutagenicity detected in Salmonella typhimurium and Chinese hamster V79 cells. Mutation Research. 281: 151-6. PMID 1371835 DOI: 10.1016/0165-7992(92)90001-X |
0.403 |
|
| 1992 |
Chen LC, Berberian I, Koch B, Mercier M, Azais-Braesco V, Glauert HP, Chow CK, Robertson LW. Polychlorinated and polybrominated biphenyl congeners and retinoid levels in rat tissues: structure-activity relationships. Toxicology and Applied Pharmacology. 114: 47-55. PMID 1316647 DOI: 10.1016/0041-008X(92)90095-A |
0.399 |
|
| 1991 |
Rodman LE, Shedlofsky SI, Mannschreck A, Püttmann M, Swim AT, Robertson LW. Differential potency of atropisomers of polychlorinated biphenyls on cytochrome P450 induction and uroporphyrin accumulation in the chick embryo hepatocyte culture. Biochemical Pharmacology. 41: 915-22. PMID 1901208 DOI: 10.1016/0006-2952(91)90196-C |
0.356 |
|
| 1991 |
Arand M, Coughtrie MW, Burchell B, Oesch F, Robertson LW. Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid. Chemico-Biological Interactions. 77: 97-105. PMID 1898504 DOI: 10.1016/0009-2797(91)90008-U |
0.516 |
|
| 1991 |
Shedlofsky SI, Hoglen NC, Rodman LE, Honchel R, Robinson FR, Swim AT, McClain CJ, Robertson LW. 3,3′,4,4′-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor Hepatology. 14: 1201-1208. DOI: 10.1002/Hep.1840140640 |
0.367 |
|
| 1991 |
Robertson LW, Silberhorn EM, Glauert HP, Schwarz M, Buchmann A. Do structure-activity relationships for the acute toxicity of pcbs and pbbs also apply for induction of hepatocellular carcinoma? Environmental Toxicology and Chemistry. 10: 715-726. DOI: 10.1002/Etc.5620100603 |
0.383 |
|
| 1990 |
Azaïs-Braesco V, Macaire JP, Bellenand P, Robertson LW, Pascal G. Effects of two prototypic polychlorinated biphenyls (PCBs) on lipid composition of rat liver and serum. The Journal of Nutritional Biochemistry. 1: 350-4. PMID 15539224 DOI: 10.1016/0955-2863(90)90002-3 |
0.378 |
|
| 1990 |
Steinberg P, Schramm H, Schladt L, Robertson LW, Thomas H, Oesch F. The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells. The Biochemical Journal. 264: 737-44. PMID 2619713 DOI: 10.1042/Bj2640737 |
0.462 |
|
| 1990 |
Borges T, Glauert HP, Chen LC, Chow CK, Robertson LW. Effect of the peroxisome proliferator perfluorodecanoic acid on growth and lipid metabolism in Sprague Dawley rats fed three dietary levels of selenium. Archives of Toxicology. 64: 26-30. PMID 2306190 DOI: 10.1007/Bf01973372 |
0.406 |
|
| 1990 |
Chen LC, Borges T, Glauert HP, Knight SA, Sunde RA, Schramm H, Oesch F, Chow CK, Robertson LW. Modulation of selenium-dependent glutathione peroxidase by perfluorodecanoic acid in rats: effect of dietary selenium. The Journal of Nutrition. 120: 298-304. PMID 2181083 DOI: 10.1093/Jn/120.3.298 |
0.543 |
|
| 1990 |
Silberhorn EM, Glauert HP, Robertson LW. Carcinogenicity of polyhalogenated biphenyls: PCBs and PBBs. Critical Reviews in Toxicology. 20: 440-96. PMID 2165409 DOI: 10.3109/10408449009029331 |
0.336 |
|
| 1990 |
Swierenga SHH, Yamasaki H, Piccoli C, Robertson L, Bourgon L, Marceau N, Fitzgerald DJ. Effects of intercellular communication in human keratinocytes and liver-derived cells of polychlorinated biphenyl congeners with differing in vivo promotion activities Carcinogenesis. 11: 921-926. PMID 2112060 DOI: 10.1093/Carcin/11.6.921 |
0.377 |
|
| 1990 |
Narbonne JF, Grolier P, Albrecht R, Azais V, Oesch F, Robertson LW. A time course investigation of vitamin A level and lipid composition of the liver endoplasmic reticulum in rats following treatment with congeneric polychlorobiphenyls Toxicology. 60: 253-261. PMID 2107605 DOI: 10.1016/0300-483X(90)90148-A |
0.55 |
|
| 1989 |
Dogra S, Filser JG, Cojocel C, Greim H, Regel U, Oesch F, Robertson LW. Long-term effects of commercial and congeneric polychlorinated biphenyls on ethane production and malondialdehyde levels, indicators of in vivo lipid peroxidation. Archives of Toxicology. 62: 369-74. PMID 3242447 DOI: 10.1007/Bf00293625 |
0.541 |
|
| 1989 |
Schramm H, Friedberg T, Robertson LW, Oesch F, Kissel W. Perfluorodecanoic acid decreases the enzyme activity and the amount of glutathione S-transferases proteins and mRNAs in vivo. Chemico-Biological Interactions. 70: 127-43. PMID 2736674 DOI: 10.1016/0009-2797(89)90068-9 |
0.437 |
|
| 1989 |
Rodman LE, Shedlofsky SI, Swim AT, Robertson LW. Effects of polychlorinated biphenyls on cytochrome P450 induction in the chick embryo hepatocyte culture. Archives of Biochemistry and Biophysics. 275: 252-62. PMID 2510602 DOI: 10.1016/0003-9861(89)90371-8 |
0.401 |
|
| 1989 |
Borlakoglu JT, Edwards-Webb JD, Dils RR, Wilkins JP, Robertson LW. Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. Febs Letters. 247: 327-9. PMID 2497034 DOI: 10.1016/0014-5793(89)81362-6 |
0.424 |
|
| 1989 |
Püttmann M, Mannschreck A, Oesch F, Robertson L. Chiral effects in the induction of drug-metabolizing enzymes using synthetic atropisomers of polychlorinated biphenyls (PCBs). Biochemical Pharmacology. 38: 1345-52. PMID 2495802 DOI: 10.1016/0006-2952(89)90342-0 |
0.476 |
|
| 1989 |
Grolier P, Cassand P, Antignac E, Narbonne JF, Albrecht R, Azais V, Robertson LW, Oesch F. Effects of prototypic PCBs on benzo[a]pyrene mutagenic activity related to vitamin A intake Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 211: 139-145. PMID 2493575 DOI: 10.1016/0027-5107(89)90114-0 |
0.529 |
|
| 1989 |
Kubiczak GA, Oesch F, Borlakoglu JT, Kunz H, Robertson LW. A unique approach to the synthesis of 2,3,4,5-substituted polybrominated biphenyls: quantitation in FireMaster FF-1 and FireMaster BP-6 Journal of Agricultural and Food Chemistry. 37: 1160-1164. DOI: 10.1021/Jf00088A075 |
0.407 |
|
| 1988 |
Amelizad Z, Narbonne JF, Wolf CR, Robertson LW, Oesch F. Effect of nutritional imbalances on cytochrome P-450 isozymes in rat liver Biochemical Pharmacology. 37: 3245-3249. PMID 3041969 DOI: 10.1016/0006-2952(88)90634-X |
0.516 |
|
| 1988 |
Rauch P, Püttmann M, Oesch F, Okamoto Y, Robertson LW. Differential induction of cytochrome P-450 by the enantiomers of trans-stilbene oxide. Biochemical Pharmacology. 36: 4355-9. PMID 2825725 DOI: 10.1016/0006-2952(87)90684-8 |
0.51 |
|
| 1987 |
Amelizad Z, Narbonne JF, Borin C, Robertson LW, Periquet A, Oesch F. Effect of unbalanced diets on incorporation of δ-aminolevulinic acid into cytochrome P-450 Febs Letters. 220: 231-235. PMID 3609316 DOI: 10.1016/0014-5793(87)80911-0 |
0.529 |
|
| 1987 |
Glatt HR, Robertson LW, Arand M, Rauch P, Schramm H, Setiabudi F, Pöchlauer P, Müller EP, Oesch F. cis- and trans-1,2-diphenylaziridines: induction of xenobiotic-metabolizing enzymes in rat liver and mutagenicity in Salmonella typhimurium. Archives of Toxicology. 59: 242-8. PMID 3548649 DOI: 10.1007/Bf00290545 |
0.468 |
|
| 1987 |
Arand M, Robertson LW, Oesch F. A fluorometric assay for quantitating phenol sulfotransferase activities in homogenates of cells and tissues. Analytical Biochemistry. 163: 546-51. PMID 3477964 DOI: 10.1016/0003-2697(87)90261-2 |
0.361 |
|
| 1987 |
Azais V, Arand M, Rauch P, Schramm H, Bellenand P, Narbonne JF, Oesch F, Pascal G, Robertson LW. A time-course investigation of vitamin A levels and drug metabolizing enzyme activities in rats following a single treatment with prototypic polychlorinated biphenyls and DDT. Toxicology. 44: 341-54. PMID 3107167 DOI: 10.1016/0300-483X(87)90035-7 |
0.498 |
|
| 1986 |
Buchmann A, Kunz W, Wolf CR, Oesch F, Robertson LW. Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats. Cancer Letters. 32: 243-53. PMID 3094931 DOI: 10.1016/0304-3835(86)90176-X |
0.499 |
|
| 1986 |
Nishihara Y, Robertson LW, Oesch F, Utsumi K. The effects of tetrachlorobiphenyls on the electron transfer reaction of isolated rat liver mitochondria. Life Sciences. 38: 627-35. PMID 3003488 DOI: 10.1016/0024-3205(86)90056-1 |
0.444 |
|
| 1986 |
Nishihara Y, Robertson LW, Oesch F, Utsumi K. Interaction of tetrachlorobiphenyls with isolated rat liver mitochondria. Journal of Pharmacobio-Dynamics. 8: 726-32. PMID 2935621 DOI: 10.1248/bpb1978.8.726 |
0.451 |
|
| 1986 |
Mönig J, Asmus K, Robertson LW, Oesch F. Polychlorinated biphenyl radical cations: a pulse radiolysis investigation Journal of the Chemical Society-Perkin Transactions 1. 17: 891-896. DOI: 10.1039/P29860000891 |
0.473 |
|
| 1986 |
Azais V, Pascal G, Arand M, Oesch F, Robertson L. Effects of congeneric polychlorinated biphenyls on liver and kidney retinoid levels Chemosphere. 15: 1905-1908. DOI: 10.1016/0045-6535(86)90480-7 |
0.47 |
|
| 1985 |
Shepherd EC, Phillips TD, Irvin TR, Safe SH, Robertson LW. Aflatoxin B1 metabolism in the rat: polyhalogenated biphenyl enhanced conversion to aflatoxin M1. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 14: 741-50. PMID 6097059 DOI: 10.3109/00498258409151472 |
0.491 |
|
| 1985 |
Schramm H, Robertson LW, Oesch F. Differential regulation of hepatic glutathione transferase and glutathione peroxidase activities in the rat. Biochemical Pharmacology. 34: 3735-9. PMID 4052112 DOI: 10.1016/0006-2952(85)90239-4 |
0.495 |
|
| 1985 |
Robertson LW, Regel U, Filser JG, Oesch F. Absence of lipid peroxidation as determined by ethane exhalation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Archives of Toxicology. 57: 13-6. PMID 4015393 DOI: 10.1007/Bf00286568 |
0.487 |
|
| 1985 |
Halvorson MR, Phillips TD, Safe SH, Robertson LW. Metabolism of aflatoxin B1 by rat hepatic microsomes induced by polyhalogenated biphenyl congeners. Applied and Environmental Microbiology. 49: 882-6. PMID 2988440 DOI: 10.1128/Aem.49.4.882-886.1985 |
0.512 |
|
| 1985 |
Safe S, Bandiera S, Sawyer T, Robertson L, Safe L, Parkinson A, Thomas PE, Ryan DE, Reik LM, Levin W, Denomme MA, Fujita T. PCBs: Structure-Function Relationships and Mechanism of Action Environmental Health Perspectives. 60: 47. DOI: 10.2307/3429944 |
0.643 |
|
| 1985 |
Mannschreck A, Pustet N, Robertson LW, Oesch F, Püttmann M. Enantiomers of Polychlorinated Biphenyls Semipreparative Enrichment by Liquid Chromatography Liebigs Annalen Der Chemie. 1985: 2101-2103. DOI: 10.1002/Chin.198604339 |
0.415 |
|
| 1984 |
Robertson LW, Parkinson A, Bandiera S, Lambert I, Merrill J, Safe SH. PCBs and PBBs: biologic and toxic effects on C57BL/6J and DBA/2J inbred mice. Toxicology. 31: 191-206. PMID 6330936 DOI: 10.1016/0300-483x(84)90101-x |
0.595 |
|
| 1984 |
Robertson LW, Thompson K, Parkinson A. Synthesis, characterization and biologic effects of polybrominated naphthalenes. Archives of Toxicology. 55: 127-31. PMID 6089700 DOI: 10.1007/BF00346051 |
0.627 |
|
| 1984 |
Robertson LW, Safe SH, Parkinson A, Pellizzari E, Pochini C, Mullin MD. Synthesis and identification of highly toxic polybrominated biphenyls in the fire retardant Firemaster BP-6 Journal of Agricultural and Food Chemistry. 32: 1107-1111. DOI: 10.1021/Jf00125A045 |
0.624 |
|
| 1983 |
Parkinson A, Robertson LW, Safe S. Binding of metyrapone to dithionite-reduced cytochrome P-450 from rats treated with xenobiotics. Biochemical Pharmacology. 31: 3489-94. PMID 7150369 DOI: 10.1016/0006-2952(82)90631-1 |
0.615 |
|
| 1983 |
Campbell MA, Bandiera S, Robertson L, Parkinson A, Safe S. Hepta-, hexa-, tetra- and dichloronaphthalene congeners as inducers of hepatic microsomal drug-metabolizing enzymes. Toxicology. 26: 193-205. PMID 6857695 DOI: 10.1016/0300-483X(83)90081-1 |
0.669 |
|
| 1983 |
Parkinson A, Thomas PE, Ryan DE, Reik LM, Safe SH, Robertson LW, Levin W. Differential time course of induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by Aroclor 1254. Archives of Biochemistry and Biophysics. 225: 203-15. PMID 6412631 DOI: 10.1016/0003-9861(83)90024-3 |
0.62 |
|
| 1983 |
Parkinson A, Robertson LW, Safe SH. Induction of rat hepatic microsomal cytochrome P-450 by 2,3',4,4',5,5'-hexachlorobiphenyl. Biochemical Pharmacology. 32: 2269-79. PMID 6409119 DOI: 10.1016/0006-2952(83)90237-X |
0.648 |
|
| 1983 |
Andres J, Lambert I, Robertson L, Bandiera S, Sawyer T, Lovering S, Safe S. The comparative biologic and toxic potencies of polychlorinated biphenyls and polybrominated biphenyls. Toxicology and Applied Pharmacology. 70: 204-15. PMID 6312630 DOI: 10.1016/0041-008X(83)90096-0 |
0.505 |
|
| 1983 |
Robertson LW, Andres JL, Safe SH, Lovering SL. Toxicity of 3,3',4,4'- and 2,2',5,5'-tetrabromobiphenyl: correlation of activity with aryl hydrocarbon hydroxylase induction and lack of protection by antioxidants. Journal of Toxicology and Environmental Health. 11: 81-91. PMID 6298436 DOI: 10.1080/15287398309530322 |
0.463 |
|
| 1983 |
Robertson LW, Parkinson A, Campbell MA, Safe S. Polybrominated biphenyls as aryl hydrocarbon hydroxylase inducers: structure-activity correlations. Chemico-Biological Interactions. 42: 53-66. PMID 6295646 DOI: 10.1016/0009-2797(82)90141-7 |
0.669 |
|
| 1983 |
Robertson LW, Chittim B, Safe SH, Mullin MD, Pochini CM. Photodecomposition of a commercial polybrominated biphenyl (PBB) fire retardant: high-resolution gas chromatographic analysis Journal of Agricultural and Food Chemistry. 31: 454-457. DOI: 10.1021/Jf00116A071 |
0.367 |
|
| 1982 |
Parkinson A, Robertson LW, Safe S. Further characterization and applications of the 4-chlorobiphenyl hydroxylase assay. Advances in Experimental Medicine and Biology. 753-9. PMID 7344491 DOI: 10.1007/978-1-4757-0674-1_57 |
0.624 |
|
| 1982 |
Bandiera S, Sawyer T, Campbell MA, Robertson L, Safe S. Halogenated biphenyls as AHH inducers: effects of different halogen substituents. Life Sciences. 31: 517-25. PMID 7132565 DOI: 10.1016/0024-3205(82)90479-9 |
0.429 |
|
| 1982 |
Parkinson A, Robertson L, Uhlig L, Campbell MA, Safe S. 2,3,4,4'-Pentachlorobiphenyl: differential effects on C57BL/6J and DBA/2J inbred mice. Biochemical Pharmacology. 31: 2830-3. PMID 6814446 DOI: 10.1016/0006-2952(82)90143-5 |
0.548 |
|
| 1982 |
Safe S, Robertson LW, Safe L, Parkinson A, Bandiera S, Sawyer T, Campbell MA. Halogenated biphenyls: molecular toxicology. Canadian Journal of Physiology and Pharmacology. 60: 1057-64. PMID 6812934 DOI: 10.1139/Y82-151 |
0.702 |
|
| 1981 |
Campbell MA, Bandiera S, Robertson L, Parkinson A, Safe S. Octachloronaphthalene induction of hepatic microsomal aryl hydrocarbon hydroxylase activity in the immature male rat. Toxicology. 22: 123-32. PMID 7324072 DOI: 10.1016/0300-483X(81)90112-8 |
0.663 |
|
| 1981 |
Parkinson A, Robertson LW, Safe S. Hepatic microsomal enzyme induction by 2,2', 3,3', 4,4'- and 2,2', 3', 4,4', 5-hexachlorobiphenyl. Life Sciences. 27: 2333-7. PMID 6782406 DOI: 10.1016/0024-3205(80)90502-0 |
0.643 |
|
| 1981 |
Parkinson A, Robertson LW, Safe L, Safe S. Polychlorinated biphenyls as inducers of hepatic microsomal enzymes: effects of di-ortho substitution. Chemico-Biological Interactions. 35: 1-12. PMID 6781768 DOI: 10.1016/0009-2797(81)90059-4 |
0.654 |
|
| 1981 |
Robertson LW, Parkinson A, Chittim B, Bandiera S, Sawyer TW, Safe S. Aryl hydrocarbon hydroxylase (AHH) induction by polybrominated biphenyls (PBBs): enchancement by photolysis. Toxicology. 22: 103-14. PMID 6275573 DOI: 10.1016/0300-483X(81)90110-4 |
0.647 |
|
| 1981 |
Robertson L, Parkinson A, Safe S. Induction of drug-metabolizing enzymes by fractionated commercial polybrominated biphenyls (PBBs). Toxicology and Applied Pharmacology. 57: 254-62. PMID 6261418 DOI: 10.1016/0041-008X(81)90287-8 |
0.618 |
|
| 1981 |
Robertson LW, Parkinson A, Bandiera S, Safe S. Potent induction of rat liver microsomal, drug-metabolizing enzymes by 2,3,3',4,4',5-hexabromobiphenyl, a component of fireMaster. Chemico-Biological Interactions. 35: 13-24. PMID 6258818 DOI: 10.1016/0009-2797(81)90060-0 |
0.647 |
|
| 1981 |
Safe S, Robertson L, Safe L, Parkinson A, Campbell M, Sawyer T, Bandiera S. POLYCHLORINATED BIPHENYLS (PCBs) AS INDUCERS OF THE HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYMES - EFFECTS OF STRUCTURE ON ACTIVITY Drug Metabolism and Drug Interactions. 3. DOI: 10.1515/Dmdi.1981.3.4.255 |
0.66 |
|
| 1980 |
Parkinson A, Robertson LW, Safe S. Reconstituted human breast milk PCBs as potent inducers of aryl hydrocarbon hydroxylase. Biochemical and Biophysical Research Communications. 96: 882-9. PMID 6775632 DOI: 10.1016/0006-291X(80)91438-2 |
0.604 |
|
| 1980 |
Parkinson A, Robertson L, Safe L, Safe S. Polychlorinated biphenyls as inducers of hepatic microsomal enzymes: structure-activity rules. Chemico-Biological Interactions. 30: 271-85. PMID 6769597 DOI: 10.1016/0009-2797(80)90050-2 |
0.668 |
|
| 1980 |
Robertson LW, Parkinson A, Safe S. Induction of both cytochromes P-450 and P-448 by 2,3',4,4',5-pentabromobiphenyl, a component of fireMaster. Biochemical and Biophysical Research Communications. 92: 175-82. PMID 6243934 DOI: 10.1016/0006-291X(80)91536-3 |
0.647 |
|
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