| Year |
Citation |
Score |
| 2023 |
Schwartz PB, Nukaya M, Berres ME, Rubinstein CD, Wu G, Hogenesch JB, Bradfield CA, Ronnekleiv-Kelly SM. The circadian clock is disrupted in pancreatic cancer. Plos Genetics. 19: e1010770. PMID 37262074 DOI: 10.1371/journal.pgen.1010770 |
0.655 |
|
| 2020 |
Avilla MN, Malecki KMC, Hahn ME, Wilson RH, Bradfield CA. The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model. Chemical Research in Toxicology. PMID 32259433 DOI: 10.1021/Acs.Chemrestox.9B00476 |
0.338 |
|
| 2019 |
Mescher M, Tigges J, Rolfes KM, Shen AL, Yee JS, Vogeley C, Krutmann J, Bradfield CA, Lang D, Haarmann-Stemmann T. The Toll-like receptor agonist imiquimod is metabolized by aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in human keratinocytes and mouse liver. Archives of Toxicology. PMID 31111189 DOI: 10.1007/S00204-019-02488-5 |
0.355 |
|
| 2018 |
O'Driscoll CA, Gallo ME, Hoffmann EJ, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD. Polycyclic aromatic hydrocarbons (PAHs) present in ambient urban dust drive proinflammatory T cell and dendritic cell responses via the aryl hydrocarbon receptor (AHR) in vitro. Plos One. 13: e0209690. PMID 30576387 DOI: 10.1371/Journal.Pone.0209690 |
0.338 |
|
| 2018 |
Clements J, Sanchez-Sedillo B, Bradfield CA, Groves RL. Transcriptomic analysis reveals similarities in genetic activation of detoxification mechanisms resulting from imidacloprid and chlorothalonil exposure. Plos One. 13: e0205881. PMID 30359414 DOI: 10.1371/Journal.Pone.0205881 |
0.334 |
|
| 2017 |
Seok SH, Ma ZX, Feltenberger JB, Chen H, Chen H, Scarlett C, Lin Z, Satyshur KA, Cortopassi M, Jefcoate CR, Ge Y, Tang W, Bradfield CA, Xing Y. Trace Derivatives of Kynurenine Potently Activate the Aryl Hydrocarbon Receptor (AHR). The Journal of Biological Chemistry. PMID 29279331 DOI: 10.1074/Jbc.Ra117.000631 |
0.356 |
|
| 2017 |
Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396409 DOI: 10.1073/Pnas.1617035114 |
0.37 |
|
| 2016 |
Shen AL, Moran SA, Glover EA, Drinkwater NR, Swearingen RE, Teixeira LB, Bradfield CA. Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression. Plos One. 11: e0157577. PMID 27310661 DOI: 10.1371/Journal.Pone.0157577 |
0.328 |
|
| 2015 |
Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, Hong H, Huang W, Omura C, Allred AL, Bradfield CA, Dinner AR, Barish GD, Bass J. Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion. Science (New York, N.Y.). 350: aac4250. PMID 26542580 DOI: 10.1126/Science.Aac4250 |
0.328 |
|
| 2014 |
Izumo M, Pejchal M, Schook AC, Lange RP, Walisser JA, Sato TR, Wang X, Bradfield CA, Takahashi JS. Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant. Elife. 3. PMID 25525750 DOI: 10.7554/Elife.04617 |
0.306 |
|
| 2014 |
Johnson BP, Walisser JA, Liu Y, Shen AL, McDearmon EL, Moran SM, McIntosh BE, Vollrath AL, Schook AC, Takahashi JS, Bradfield CA. Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proceedings of the National Academy of Sciences of the United States of America. 111: 18757-62. PMID 25512522 DOI: 10.1073/Pnas.1421708111 |
0.764 |
|
| 2014 |
Liu Y, Johnson BP, Shen AL, Wallisser JA, Krentz KJ, Moran SM, Sullivan R, Glover E, Parlow AF, Drinkwater NR, Schuler LA, Bradfield CA. Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 14295-300. PMID 25225411 DOI: 10.1073/Pnas.1209249111 |
0.574 |
|
| 2014 |
Sengupta S, Johnson BP, Swanson SA, Stewart R, Bradfield CA, Thomson JA. Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 236-45. PMID 24752503 DOI: 10.1093/Toxsci/Kfu069 |
0.505 |
|
| 2014 |
Kennedy GD, Nukaya M, Moran SM, Glover E, Weinberg S, Balbo S, Hecht SS, Pitot HC, Drinkwater NR, Bradfield CA. Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 135-43. PMID 24718703 DOI: 10.1093/Toxsci/Kfu065 |
0.322 |
|
| 2013 |
Sievers CK, Shanle EK, Bradfield CA, Xu W. Differential action of monohydroxylated polycyclic aromatic hydrocarbons with estrogen receptors α and β. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 359-67. PMID 22989670 DOI: 10.1093/Toxsci/Kfs287 |
0.362 |
|
| 2012 |
Paschos GK, Ibrahim S, Song WL, Kunieda T, Grant G, Reyes TM, Bradfield CA, Vaughan CH, Eiden M, Masoodi M, Griffin JL, Wang F, Lawson JA, Fitzgerald GA. Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nature Medicine. 18: 1768-77. PMID 23142819 DOI: 10.1038/Nm.2979 |
0.308 |
|
| 2012 |
Pauly SK, Fechner JH, Zhang X, Torrealba J, Bradfield CA, Mezrich JD. The Aryl Hydrocarbon Receptor Influences Transplant Outcomes in Response to Environmental Signals. Toxicological and Environmental Chemistry. 94: 1175-1187. PMID 23002321 DOI: 10.1080/02772248.2012.688546 |
0.334 |
|
| 2012 |
Mezrich JD, Nguyen LP, Kennedy G, Nukaya M, Fechner JH, Zhang X, Xing Y, Bradfield CA. SU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulation. Plos One. 7: e44547. PMID 22970246 DOI: 10.1371/Journal.Pone.0044547 |
0.581 |
|
| 2012 |
Xing Y, Nukaya M, Satyshur KA, Jiang L, Stanevich V, Korkmaz EN, Burdette L, Kennedy GD, Cui Q, Bradfield CA. Identification of the Ah-receptor structural determinants for ligand preferences. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 86-97. PMID 22659362 DOI: 10.1093/Toxsci/Kfs194 |
0.344 |
|
| 2012 |
Lee JS, Cella M, McDonald KG, Garlanda C, Kennedy GD, Nukaya M, Mantovani A, Kopan R, Bradfield CA, Newberry RD, Colonna M. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nature Immunology. 13: 144-51. PMID 22101730 DOI: 10.1038/Ni.2187 |
0.308 |
|
| 2011 |
Chernoff N, Rogers EH, Zehr RD, Gage MI, Malarkey DE, Bradfield CA, Liu Y, Schmid JE, Jaskot RH, Richards JH, Wood CR, Rosen MB. Toxicity and recovery in the pregnant mouse after gestational exposure to the cyanobacterial toxin, cylindrospermopsin. Journal of Applied Toxicology : Jat. 31: 242-54. PMID 20936652 DOI: 10.1002/Jat.1586 |
0.323 |
|
| 2010 |
Nukaya M, Walisser JA, Moran SM, Kennedy GD, Bradfield CA. Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 554-63. PMID 20935161 DOI: 10.1093/Toxsci/Kfq305 |
0.432 |
|
| 2010 |
Nukaya M, Lin BC, Glover E, Moran SM, Kennedy GD, Bradfield CA. The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes. The Journal of Biological Chemistry. 285: 35599-605. PMID 20829355 DOI: 10.1074/Jbc.M110.132043 |
0.657 |
|
| 2010 |
Shen AL, O'Leary KA, Dubielzig RR, Drinkwater N, Murphy CJ, Kasper CB, Bradfield CA. The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene. Plos One. 5: e12213. PMID 20808945 DOI: 10.1371/Journal.Pone.0012213 |
0.321 |
|
| 2010 |
Mezrich JD, Fechner JH, Zhang X, Johnson BP, Burlingham WJ, Bradfield CA. An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 3190-8. PMID 20720200 DOI: 10.4049/Jimmunol.0903670 |
0.538 |
|
| 2010 |
McIntosh BE, Hogenesch JB, Bradfield CA. Mammalian Per-Arnt-Sim proteins in environmental adaptation. Annual Review of Physiology. 72: 625-45. PMID 20148691 DOI: 10.1146/Annurev-Physiol-021909-135922 |
0.778 |
|
| 2009 |
Nguyen LP, Hsu EL, Chowdhury G, Dostalek M, Guengerich FP, Bradfield CA. D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan. Chemical Research in Toxicology. 22: 1897-904. PMID 19860415 DOI: 10.1021/Tx900043S |
0.549 |
|
| 2009 |
Chowdhury G, Dostalek M, Hsu EL, Nguyen LP, Stec DF, Bradfield CA, Guengerich FP. Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid. Chemical Research in Toxicology. 22: 1905-12. PMID 19860413 DOI: 10.1021/Tx9000418 |
0.518 |
|
| 2009 |
Vollrath AL, Smith AA, Craven M, Bradfield CA. EDGE(3): a web-based solution for management and analysis of Agilent two color microarray experiments. Bmc Bioinformatics. 10: 280. PMID 19732451 DOI: 10.1186/1471-2105-10-280 |
0.766 |
|
| 2009 |
Stevens EA, Mezrich JD, Bradfield CA. The aryl hydrocarbon receptor: a perspective on potential roles in the immune system. Immunology. 127: 299-311. PMID 19538249 DOI: 10.1111/J.1365-2567.2009.03054.X |
0.615 |
|
| 2009 |
Smith AA, Vollrath A, Bradfield CA, Craven M. Clustered alignments of gene-expression time series data. Bioinformatics (Oxford, England). 25: i119-27. PMID 19477977 DOI: 10.1093/Bioinformatics/Btp206 |
0.768 |
|
| 2009 |
Nukaya M, Moran S, Bradfield CA. The role of the dioxin-responsive element cluster between the Cyp1a1 and Cyp1a2 loci in aryl hydrocarbon receptor biology. Proceedings of the National Academy of Sciences of the United States of America. 106: 4923-8. PMID 19261855 DOI: 10.1073/Pnas.0809613106 |
0.418 |
|
| 2008 |
Lin BC, Nguyen LP, Walisser JA, Bradfield CA. A hypomorphic allele of aryl hydrocarbon receptor-associated protein-9 produces a phenocopy of the AHR-null mouse. Molecular Pharmacology. 74: 1367-71. PMID 18669605 DOI: 10.1124/Mol.108.047068 |
0.707 |
|
| 2008 |
Bunger MK, Glover E, Moran SM, Walisser JA, Lahvis GP, Hsu EL, Bradfield CA. Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 106: 83-92. PMID 18660548 DOI: 10.1093/Toxsci/Kfn149 |
0.78 |
|
| 2008 |
Smith AA, Vollrath A, Bradfield CA, Craven M. Similarity queries for temporal toxicogenomic expression profiles. Plos Computational Biology. 4: e1000116. PMID 18636114 DOI: 10.1371/Journal.Pcbi.1000116 |
0.767 |
|
| 2008 |
Stevens EA, Bradfield CA. Immunology: T cells hang in the balance. Nature. 453: 46-7. PMID 18451850 DOI: 10.1038/453046A |
0.557 |
|
| 2008 |
Westgate EJ, Cheng Y, Reilly DF, Price TS, Walisser JA, Bradfield CA, FitzGerald GA. Genetic components of the circadian clock regulate thrombogenesis in vivo. Circulation. 117: 2087-95. PMID 18413500 DOI: 10.1161/Circulationaha.107.739227 |
0.319 |
|
| 2008 |
Nguyen LP, Bradfield CA. The search for endogenous activators of the aryl hydrocarbon receptor. Chemical Research in Toxicology. 21: 102-16. PMID 18076143 DOI: 10.1021/Tx7001965 |
0.59 |
|
| 2008 |
Smith AA, Vollrath A, Bradfield CA, Craven M. Correction: Similarity Queries for Temporal Toxicogenomic Expression Profiles Plos Computational Biology. 4. DOI: 10.1371/Annotation/48Ea9Acf-4422-4792-B9A6-565De3E64F60 |
0.755 |
|
| 2008 |
Vollrath AL, Bradfield CA. An Introduction to Toxicogenomics Drug Metabolism Handbook: Concepts and Applications. 737-759. DOI: 10.1002/9780470439265.ch25 |
0.744 |
|
| 2007 |
Hayes KR, Zastrow GM, Nukaya M, Pande K, Glover E, Maufort JP, Liss AL, Liu Y, Moran SM, Vollrath AL, Bradfield CA. Hepatic transcriptional networks induced by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemical Research in Toxicology. 20: 1573-81. PMID 17949056 DOI: 10.1021/Tx7003294 |
0.778 |
|
| 2007 |
Lin BC, Sullivan R, Lee Y, Moran S, Glover E, Bradfield CA. Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality. The Journal of Biological Chemistry. 282: 35924-32. PMID 17916558 DOI: 10.1074/Jbc.M705471200 |
0.617 |
|
| 2007 |
McMillan BJ, Bradfield CA. The aryl hydrocarbon receptor sans xenobiotics: endogenous function in genetic model systems. Molecular Pharmacology. 72: 487-98. PMID 17535977 DOI: 10.1124/Mol.107.037259 |
0.645 |
|
| 2007 |
McMillan BJ, McMillan SN, Glover E, Bradfield CA. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces premature activation of the KLF2 regulon during thymocyte development. The Journal of Biological Chemistry. 282: 12590-7. PMID 17337447 DOI: 10.1074/Jbc.M611446200 |
0.626 |
|
| 2007 |
McMillan BJ, Bradfield CA. The aryl hydrocarbon receptor is activated by modified low-density lipoprotein. Proceedings of the National Academy of Sciences of the United States of America. 104: 1412-7. PMID 17227852 DOI: 10.1073/Pnas.0607296104 |
0.639 |
|
| 2006 |
McDearmon EL, Patel KN, Ko CH, Walisser JA, Schook AC, Chong JL, Wilsbacher LD, Song EJ, Hong HK, Bradfield CA, Takahashi JS. Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science (New York, N.Y.). 314: 1304-8. PMID 17124323 DOI: 10.1126/Science.1132430 |
0.338 |
|
| 2006 |
Dunham EE, Stevens EA, Glover E, Bradfield CA. The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein. Molecular Pharmacology. 70: 8-15. PMID 16582008 DOI: 10.1124/Mol.106.024380 |
0.788 |
|
| 2006 |
Harstad EB, Guite CA, Thomae TL, Bradfield CA. Liver deformation in Ahr-null mice: evidence for aberrant hepatic perfusion in early development. Molecular Pharmacology. 69: 1534-41. PMID 16443691 DOI: 10.1124/Mol.105.020107 |
0.768 |
|
| 2006 |
Thomae TL, Stevens EA, Liss AL, Drinkwater NR, Bradfield CA. The teratogenic sensitivity to 2,3,7,8-tetrachlorodibenzo-p-dioxin is modified by a locus on mouse chromosome 3. Molecular Pharmacology. 69: 770-5. PMID 16354765 DOI: 10.1124/Mol.105.019760 |
0.77 |
|
| 2005 |
Walisser JA, Glover E, Pande K, Liss AL, Bradfield CA. Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types. Proceedings of the National Academy of Sciences of the United States of America. 102: 17858-63. PMID 16301529 DOI: 10.1073/Pnas.0504757102 |
0.648 |
|
| 2005 |
Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Molecular and Cellular Biology. 25: 3163-72. PMID 15798202 DOI: 10.1128/Mcb.25.8.3163-3172.2005 |
0.334 |
|
| 2005 |
Hayes KR, Bradfield CA. Advances in toxicogenomics. Chemical Research in Toxicology. 18: 403-14. PMID 15777080 DOI: 10.1021/Tx0496690 |
0.686 |
|
| 2005 |
Bunger MK, Walisser JA, Sullivan R, Manley PA, Moran SM, Kalscheur VL, Colman RJ, Bradfield CA. Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus. Genesis (New York, N.Y. : 2000). 41: 122-32. PMID 15739187 DOI: 10.1002/Gene.20102 |
0.743 |
|
| 2005 |
Pande K, Moran SM, Bradfield CA. Aspects of dioxin toxicity are mediated by interleukin 1-like cytokines. Molecular Pharmacology. 67: 1393-8. PMID 15722456 DOI: 10.1124/Mol.105.010983 |
0.614 |
|
| 2005 |
Thomae TL, Stevens EA, Bradfield CA. Transforming growth factor-beta3 restores fusion in palatal shelves exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. The Journal of Biological Chemistry. 280: 12742-6. PMID 15668235 DOI: 10.1074/Jbc.M410780200 |
0.781 |
|
| 2005 |
Hayes KR, Vollrath AL, Zastrow GM, McMillan BJ, Craven M, Jovanovich S, Rank DR, Penn S, Walisser JA, Reddy JK, Thomas RS, Bradfield CA. EDGE: a centralized resource for the comparison, analysis, and distribution of toxicogenomic information. Molecular Pharmacology. 67: 1360-8. PMID 15662043 DOI: 10.1124/Mol.104.009175 |
0.758 |
|
| 2005 |
Lahvis GP, Pyzalski RW, Glover E, Pitot HC, McElwee MK, Bradfield CA. The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse. Molecular Pharmacology. 67: 714-20. PMID 15590894 DOI: 10.1124/Mol.104.008888 |
0.341 |
|
| 2005 |
Williams SN, Dunham E, Bradfield CA. Induction of cytochrome P450 enzymes Cytochrome P450: Structure, Mechanism, and Biochemistry: Third Edition. 323-346. DOI: 10.1007/0-387-27447-2_8 |
0.708 |
|
| 2004 |
Walisser JA, Bunger MK, Glover E, Bradfield CA. Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development. Proceedings of the National Academy of Sciences of the United States of America. 101: 16677-82. PMID 15545609 DOI: 10.1073/Pnas.0404379101 |
0.776 |
|
| 2004 |
Thomae TL, Glover E, Bradfield CA. A maternal Ahr null genotype sensitizes embryos to chemical teratogenesis. The Journal of Biological Chemistry. 279: 30189-94. PMID 15145931 DOI: 10.1074/Jbc.M403690200 |
0.784 |
|
| 2004 |
Yao G, Craven M, Drinkwater N, Bradfield CA. Interaction networks in yeast define and enumerate the signaling steps of the vertebrate aryl hydrocarbon receptor. Plos Biology. 2: E65. PMID 15024417 DOI: 10.1371/Journal.Pbio.0020065 |
0.582 |
|
| 2004 |
Peter Guengerich F, Martin MV, McCormick WA, Nguyen LP, Glover E, Bradfield CA. Aryl hydrocarbon receptor response to indigoids in vitro and in vivo. Archives of Biochemistry and Biophysics. 423: 309-16. PMID 15001395 DOI: 10.1016/J.Abb.2004.01.002 |
0.547 |
|
| 2004 |
Walisser JA, Bunger MK, Glover E, Harstad EB, Bradfield CA. Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele. The Journal of Biological Chemistry. 279: 16326-31. PMID 14764592 DOI: 10.1074/Jbc.M400784200 |
0.789 |
|
| 2003 |
Bittinger MA, Nguyen LP, Bradfield CA. Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor. Molecular Pharmacology. 64: 550-6. PMID 12920190 DOI: 10.1124/Mol.64.3.550 |
0.581 |
|
| 2003 |
Bunger MK, Moran SM, Glover E, Thomae TL, Lahvis GP, Lin BC, Bradfield CA. Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 278: 17767-74. PMID 12621046 DOI: 10.1074/Jbc.M209594200 |
0.788 |
|
| 2002 |
Thomas RS, Rank DR, Penn SG, Zastrow GM, Hayes KR, Hu T, Pande K, Lewis M, Jovanovich SB, Bradfield CA. Application of genomics to toxicology research. Environmental Health Perspectives. 110: 919-23. PMID 12634120 DOI: 10.1289/Ehp.02110S6919 |
0.767 |
|
| 2002 |
Thomas RS, Rank DR, Penn SG, Craven MW, Drinkwater NR, Bradfield CA. Developing toxicologically predictive gene sets using cDNA microarrays and Bayesian classification. Methods in Enzymology. 357: 198-205. PMID 12424911 DOI: 10.1016/S0076-6879(02)57679-5 |
0.3 |
|
| 2002 |
Thomas RS, Penn SG, Holden K, Bradfield CA, Rank DR. Sequence variation and phylogenetic history of the mouse Ahr gene. Pharmacogenetics. 12: 151-63. PMID 11875369 DOI: 10.1097/00008571-200203000-00009 |
0.342 |
|
| 2001 |
Thomas RS, Rank DR, Penn SG, Zastrow GM, Hayes KR, Pande K, Glover E, Silander T, Craven MW, Reddy JK, Jovanovich SB, Bradfield CA. Identification of toxicologically predictive gene sets using cDNA microarrays. Molecular Pharmacology. 60: 1189-94. PMID 11723225 DOI: 10.1124/Mol.60.6.1189 |
0.792 |
|
| 2000 |
Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell. 103: 1009-17. PMID 11163178 DOI: 10.1016/S0092-8674(00)00205-1 |
0.779 |
|
| 2000 |
Lahvis GP, Lindell SL, Thomas RS, McCuskey RS, Murphy C, Glover E, Bentz M, Southard J, Bradfield CA. Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 10442-7. PMID 10973493 DOI: 10.1073/Pnas.190256997 |
0.364 |
|
| 2000 |
Hogenesch JB, Gu YZ, Moran SM, Shimomura K, Radcliffe LA, Takahashi JS, Bradfield CA. The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC83. PMID 10864977 DOI: 10.1523/Jneurosci.20-13-J0002.2000 |
0.692 |
|
| 2000 |
Gu YZ, Hogenesch JB, Bradfield CA. The PAS superfamily: sensors of environmental and developmental signals. Annual Review of Pharmacology and Toxicology. 40: 519-61. PMID 10836146 DOI: 10.1146/Annurev.Pharmtox.40.1.519 |
0.678 |
|
| 2000 |
LaPres JJ, Glover E, Dunham EE, Bunger MK, Bradfield CA. ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor. The Journal of Biological Chemistry. 275: 6153-9. PMID 10692406 DOI: 10.1074/Jbc.275.9.6153 |
0.785 |
|
| 1999 |
Chan WK, Yao G, Gu YZ, Bradfield CA. Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation. The Journal of Biological Chemistry. 274: 12115-23. PMID 10207038 DOI: 10.1074/Jbc.274.17.12115 |
0.598 |
|
| 1998 |
Bunger MK, Bradfield CA. Generation of allelic series in mice by gene targeting. Methods in Molecular Biology (Clifton, N.J.). 107: 439-68. PMID 14577251 DOI: 10.1385/0-89603-519-0:439 |
0.741 |
|
| 1998 |
Gu YZ, Moran SM, Hogenesch JB, Wartman L, Bradfield CA. Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha. Gene Expression. 7: 205-13. PMID 9840812 |
0.65 |
|
| 1998 |
Carver LA, LaPres JJ, Jain S, Dunham EE, Bradfield CA. Characterization of the Ah receptor-associated protein, ARA9. The Journal of Biological Chemistry. 273: 33580-7. PMID 9837941 DOI: 10.1074/Jbc.273.50.33580 |
0.76 |
|
| 1998 |
Lahvis GP, Bradfield CA. Ahr null alleles: distinctive or different? Biochemical Pharmacology. 56: 781-7. PMID 9774139 DOI: 10.1016/S0006-2952(98)00134-8 |
0.329 |
|
| 1998 |
Hogenesch JB, Gu YZ, Jain S, Bradfield CA. The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proceedings of the National Academy of Sciences of the United States of America. 95: 5474-9. PMID 9576906 DOI: 10.1073/Pnas.95.10.5474 |
0.687 |
|
| 1998 |
Jain S, Maltepe E, Lu MM, Simon C, Bradfield CA. Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. Mechanisms of Development. 73: 117-23. PMID 9545558 DOI: 10.1016/S0925-4773(98)00038-0 |
0.332 |
|
| 1998 |
Powell-Coffman JA, Bradfield CA, Wood WB. Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator. Proceedings of the National Academy of Sciences of the United States of America. 95: 2844-9. PMID 9501178 DOI: 10.1073/Pnas.95.6.2844 |
0.408 |
|
| 1997 |
Luo G, Gu YZ, Jain S, Chan WK, Carr KM, Hogenesch JB, Bradfield CA. Molecular characterization of the murine Hif-1 alpha locus. Gene Expression. 6: 287-99. PMID 9368100 |
0.649 |
|
| 1997 |
Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature. 386: 403-7. PMID 9121557 DOI: 10.1038/386403A0 |
0.36 |
|
| 1997 |
Carver LA, Bradfield CA. Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. The Journal of Biological Chemistry. 272: 11452-6. PMID 9111057 DOI: 10.1074/Jbc.272.17.11452 |
0.346 |
|
| 1997 |
Hogenesch JB, Chan WK, Jackiw VH, Brown RC, Gu YZ, Pray-Grant M, Perdew GH, Bradfield CA. Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. The Journal of Biological Chemistry. 272: 8581-93. PMID 9079689 DOI: 10.1074/jbc.272.13.8581 |
0.684 |
|
| 1996 |
Schmidt JV, Bradfield CA. Ah receptor signaling pathways. Annual Review of Cell and Developmental Biology. 12: 55-89. PMID 8970722 DOI: 10.1146/Annurev.Cellbio.12.1.55 |
0.411 |
|
| 1996 |
Perdew GH, Bradfield CA. Mapping the 90 kDa heat shock protein binding region of the Ah receptor. Biochemistry and Molecular Biology International. 39: 589-93. PMID 8828811 DOI: 10.1080/15216549600201651 |
0.31 |
|
| 1996 |
Schmidt JV, Su GH, Reddy JK, Simon MC, Bradfield CA. Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proceedings of the National Academy of Sciences of the United States of America. 93: 6731-6. PMID 8692887 DOI: 10.1073/Pnas.93.13.6731 |
0.39 |
|
| 1995 |
Swanson HI, Chan WK, Bradfield CA. DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. The Journal of Biological Chemistry. 270: 26292-302. PMID 7592839 DOI: 10.1074/Jbc.270.44.26292 |
0.317 |
|
| 1994 |
Le Beau MM, Carver LA, Espinosa R, Schmidt JV, Bradfield CA. Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15. Cytogenetics and Cell Genetics. 66: 172-6. PMID 8125016 DOI: 10.1159/000133694 |
0.362 |
|
| 1994 |
Carver LA, Hogenesch JB, Bradfield CA. Tissue specific expression of the rat Ah-receptor and ARNT mRNAs. Nucleic Acids Research. 22: 3038-44. PMID 8065918 DOI: 10.1093/Nar/22.15.3038 |
0.698 |
|
| 1993 |
Dolwick KM, Swanson HI, Bradfield CA. In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition. Proceedings of the National Academy of Sciences of the United States of America. 90: 8566-70. PMID 8397410 DOI: 10.1073/Pnas.90.18.8566 |
0.345 |
|
| 1993 |
Swanson HI, Bradfield CA. The AH-receptor: genetics, structure and function. Pharmacogenetics. 3: 213-30. PMID 8287061 DOI: 10.1097/00008571-199310000-00001 |
0.383 |
|
| 1992 |
Poland A, Bradfield C. A brief review of the Ah locus. The Tohoku Journal of Experimental Medicine. 168: 83-7. PMID 1339107 DOI: 10.1620/Tjem.168.83 |
0.363 |
|
| 1992 |
Burbach KM, Poland A, Bradfield CA. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 89: 8185-9. PMID 1325649 DOI: 10.1073/Pnas.89.17.8185 |
0.355 |
|
| 1991 |
Bradfield CA, Bjeldanes LF. Modification of carcinogen metabolism by indolylic autolysis products of Brassica oleraceae. Advances in Experimental Medicine and Biology. 289: 153-63. PMID 1897390 DOI: 10.1007/978-1-4899-2626-5_13 |
0.566 |
|
| 1991 |
Bjeldanes LF, Kim JY, Grose KR, Bartholomew JC, Bradfield CA. Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proceedings of the National Academy of Sciences of the United States of America. 88: 9543-7. PMID 1658785 DOI: 10.1073/Pnas.88.21.9543 |
0.561 |
|
| 1987 |
Bradfield CA, Bjeldanes LF. Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism. Journal of Toxicology and Environmental Health. 21: 311-23. PMID 3495667 DOI: 10.1080/15287398709531021 |
0.538 |
|
| 1987 |
Bradfield CA, Bjeldanes LF. Dietary modification of xenobiotic metabolism: Contribution of indolylic compounds present in Brassica oleracea Journal of Agricultural and Food Chemistry. 35: 896-900. DOI: 10.1021/Jf00078A011 |
0.556 |
|
| 1987 |
Bradfield CA, Bjeldanes LF. High-performance liquid chromatographic analysis of anticarcinogenic indoles in Brassica oleracea Journal of Agricultural and Food Chemistry. 35: 46-49. DOI: 10.1021/Jf00073A010 |
0.525 |
|
| 1985 |
Bradfield CA, Chang Y, Bjeldanes LF. Effects of commonly consumed vegetables on hepatic xenobiotic-metabolizing enzymes in the mouse. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 23: 899-904. PMID 3877667 DOI: 10.1016/0278-6915(85)90105-X |
0.544 |
|
| 1984 |
Bradfield CA, Bjeldanes LF. Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the rat. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 22: 977-82. PMID 6334634 DOI: 10.1016/0278-6915(84)90147-9 |
0.51 |
|
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