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James E. Bear, Ph.D. - Related publications

Cell and Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
cell migration
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Vasilev F, Ezhova Y, Chun JT. Signaling Enzymes and Ion Channels Being Modulated by the Actin Cytoskeleton at the Plasma Membrane. International Journal of Molecular Sciences. 22. PMID 34638705 DOI: 10.3390/ijms221910366   
2021 Leung G, Zhou Y, Ostrowski P, Mylvaganam S, Boroumand P, Mulder DJ, Guo C, Muise AM, Freeman S. ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells. Jci Insight. PMID 34673575 DOI: 10.1172/jci.insight.149376   
2021 Zhang Z, Liu R, Wang Y, Wang Y, Shuai Y, Ke C, Jin R, Wang X, Luo J. Phosphorylation of MICAL2 by ARG promotes head and neck cancer tumorigenesis by regulating skeletal rearrangement. Oncogene. PMID 34750518 DOI: 10.1038/s41388-021-02101-z   
2021 Peng JM, Chen WY, Cheng JH, Luo JW, Tzeng HT. Dysregulation of Cytoskeleton Remodeling Drives Invasive Leading Cells Detachment. Cancers. 13. PMID 34830801 DOI: 10.3390/cancers13225648   
2021 Ghosh S, Gutti S, Chaudhuri D. Pattern formation, localized and running pulsation on active spherical membranes. Soft Matter. PMID 34605510 DOI: 10.1039/d1sm00937k   
2021 Lamb MC, Kaluarachchi CP, Lansakara TI, Mellentine SQ, Lan Y, Tivanski AV, Tootle TL. Fascin limits Myosin activity within border cells to control substrate stiffness and promote migration. Elife. 10. PMID 34698017 DOI: 10.7554/eLife.69836   
2021 Biber G, Ben-Shmuel A, Noy E, Joseph N, Puthenveetil A, Reiss N, Levy O, Lazar I, Feiglin A, Ofran Y, Kedmi M, Avigdor A, Fried S, Barda-Saad M. Targeting the actin nucleation promoting factor WASp provides a therapeutic approach for hematopoietic malignancies. Nature Communications. 12: 5581. PMID 34552085 DOI: 10.1038/s41467-021-25842-7   
2021 Hu H, Zhang S, Xiong S, Hu B, He Y, Gu Y. ACTR3 promotes cell migration and invasion by inducing epithelial mesenchymal transition in pancreatic ductal adenocarcinoma. Journal of Gastrointestinal Oncology. 12: 2325-2333. PMID 34790395 DOI: 10.21037/jgo-21-609   
2021 Rana PS, Alkrekshi A, Wang W, Markovic V, Sossey-Alaoui K. The Role of WAVE2 Signaling in Cancer. Biomedicines. 9. PMID 34572403 DOI: 10.3390/biomedicines9091217   
2021 Titelbaum M, Brant B, Baumel D, Burstein-Willensky A, Perez S, Barsheshet Y, Avni O. Ezh2 harnesses the intranuclear actin cytoskeleton to remodel chromatin in differentiating Th cells. Iscience. 24: 103093. PMID 34622148 DOI: 10.1016/j.isci.2021.103093   
2021 Liu J, Kang L, Smith S, Wang C. Transmembrane MUC18 Targeted Polydopamine Nanoparticles and a Mild Photothermal Effect Synergistically Disrupt Actin Cytoskeleton and Migration of Cancer Cells. Nano Letters. PMID 34726401 DOI: 10.1021/acs.nanolett.1c03377   
2021 Liu ZZG, Taiyab A, West-Mays JA. MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens. International Journal of Molecular Sciences. 22. PMID 34769418 DOI: 10.3390/ijms222111988   
2021 Malla M, Pollard TD, Chen Q. Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis. Molecular Biology of the Cell. mbcE21080376. PMID 34613787 DOI: 10.1091/mbc.E21-08-0376   
2021 Law AL, Jalal S, Pallett T, Mosis F, Guni A, Brayford S, Yolland L, Marcotti S, Levitt JA, Poland SP, Rowe-Sampson M, Jandke A, Köchl R, Pula G, Ameer-Beg SM, et al. Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration. Nature Communications. 12: 5687. PMID 34584076 DOI: 10.1038/s41467-021-25916-6   
2021 Zhang H, Cheng Z, Li W, Hu J, Zhao L, Chen D, Gao J, Chen J, Yan Y, Lin L, Shi A. WTS-1/LATS regulates endocytic recycling by restraining F-actin assembly in a synergistic manner. Journal of Cell Science. PMID 34817059 DOI: 10.1242/jcs.259085   
2021 Lamptey J, Czika A, Aremu JO, Pervaz S, Adu-Gyamfi EA, Otoo A, Li F, Wang YX, Ding YB. The Role of Fascin in Carcinogenesis and Embryogenesis. Experimental Cell Research. 112885. PMID 34662557 DOI: 10.1016/j.yexcr.2021.112885   
2021 Bock F, Elias BC, Dong X, Parekh DV, Mernaugh G, Viquez OM, Hassan A, Amara VR, Liu J, Brown KL, Terker AS, Chiusa M, Gewin LS, Fogo AB, Brakebusch CH, et al. Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity. The Journal of Cell Biology. 220. PMID 34647970 DOI: 10.1083/jcb.202103080   
2021 Feng Y, Shi R, Hu J, Lou S. Effects of neural-derived estradiol on actin polymerization and synaptic plasticity-related proteins in prefrontal and hippocampal cells of mice. Steroids. 108935. PMID 34715132 DOI: 10.1016/j.steroids.2021.108935   
2021 Rutkowski DM, Vavylonis D. Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes. Plos Computational Biology. 17: e1009506. PMID 34662335 DOI: 10.1371/journal.pcbi.1009506   
2021 Stark BC, Gao Y, Sepich DS, Belk L, Culver MA, Hu B, Mekel M, Ferris W, Shin J, Solnica-Krezel L, Lin F, Cooper JA. CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish. Developmental Biology. PMID 34599906 DOI: 10.1016/j.ydbio.2021.09.008   
2021 Vaddepalli P, de Zeeuw T, Strauss S, Bürstenbinder K, Liao CY, Ramalho JJ, Smith RS, Weijers D. Auxin-dependent control of cytoskeleton and cell shape regulates division orientation in the Arabidopsis embryo. Current Biology : Cb. PMID 34610273 DOI: 10.1016/j.cub.2021.09.019   
2021 Shi X, Tang D, Xing Y, Zhao S, Fan C, Zhong J, Cui Y, Shi K, Jiu Y. Actin nucleator formins regulate the tension-buffering function of caveolin-1. Journal of Molecular Cell Biology. PMID 34718633 DOI: 10.1093/jmcb/mjab070   
2021 Marco S, Neilson M, Moore M, Perez-Garcia A, Hall H, Mitchell L, Lilla S, Blanco GR, Hedley A, Zanivan S, Norman JC. Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion. Nature Communications. 12: 6829. PMID 34819513 DOI: 10.1038/s41467-021-26839-y   
2021 Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J. Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors. Elife. 10. PMID 34796874 DOI: 10.7554/eLife.65910   
2021 Lin YS, Chang TH, Ho WC, Chang SF, Chen YL, Chang ST, Chen HC, Pan KL, Chen MC. Sarcomeres Morphology and Z-Line Arrangement Disarray Induced by Ventricular Premature Contractions through the Rac2/Cofilin Pathway. International Journal of Molecular Sciences. 22. PMID 34681906 DOI: 10.3390/ijms222011244   
2021 Zweifel ME, Sherer LA, Mahanta B, Courtemanche N. Nucleation limits the lengths of actin filaments assembled by formin. Biophysical Journal. 120: 4442-4456. PMID 34506773 DOI: 10.1016/j.bpj.2021.09.003   
2021 Bashirzadeh Y, Redford SA, Lorpaiboon C, Groaz A, Moghimianavval H, Litschel T, Schwille P, Hocky GM, Dinner AR, Liu AP. Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture. Communications Biology. 4: 1136. PMID 34584211 DOI: 10.1038/s42003-021-02653-6   
2021 Mascarenhas JB, Gaber AA, Larrinaga TM, Mayfield R, Novak S, Camp SM, Gregorio C, Jacobson JR, Cress AE, Dudek SM, Garcia JGN. EVL is a novel focal adhesion protein involved in the regulation of cytoskeletal dynamics and vascular permeability. Pulmonary Circulation. 11: 20458940211049002. PMID 34631011 DOI: 10.1177/20458940211049002   
2021 Filho EGF, da Silva EZM, Ong HL, Swaim WD, Ambudkar IS, Oliver C, Jamur MC. RACK1 plays a critical role in mast cell secretion and Ca2+ mobilization by modulating F-actin dynamics. Journal of Cell Science. 134. PMID 34550354 DOI: 10.1242/jcs.252585   
2021 Tan Y, Jin Y, Zhao P, Wu J, Ren Z. Lipid droplets contribute myogenic differentiation in C2C12 by promoting the remodeling of the acstin-filament. Cell Death & Disease. 12: 1102. PMID 34815388 DOI: 10.1038/s41419-021-04273-8   
2021 Hatakeyama J, Nomura M, Wakimoto Y, Inoue S, Li C, Takamura D, Akisue T, Moriyama H. Effects of cyclic tensile strain and microgravity on the distribution of actin fiber and Fat1 cadherin in murine articular chondrocytes. Journal of Biomechanics. 129: 110774. PMID 34627073 DOI: 10.1016/j.jbiomech.2021.110774   
2021 Ma Z, Sun Y, Zhu X, Yang L, Chen X, Miao Y. Membrane nanodomains modulate formin condensation for actin remodeling in Arabidopsis innate immune responses. The Plant Cell. PMID 34726756 DOI: 10.1093/plcell/koab261   
2021 Kubota H, Ogawa H, Miyazaki M, Ishii S, Oyama K, Kawamura Y, Ishiwata S, Suzuki M. Microscopic Temperature Control Reveals Cooperative Regulation of Actin-Myosin Interaction by Drebrin E. Nano Letters. PMID 34751025 DOI: 10.1021/acs.nanolett.1c02955   
2021 Barai A, Mukherjee A, Das A, Saxena N, Sen S. α-actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization. Journal of Cell Science. PMID 34730180 DOI: 10.1242/jcs.258581   
2021 Chen J, Kaw K, Lu H, Fagnant PM, Chattopadhyay A, Duan XY, Zhou Z, Ma S, Liu Z, Huang J, Kamm K, Stull JT, Kwartler CS, Trybus KM, Milewicz DM. Resistance of Acta2 Mice to Aortic Disease is Associated with Defective Release of Mutant Smooth Muscle α-actin from the Chaperonin-containing TCP1 folding complex. The Journal of Biological Chemistry. 101228. PMID 34600884 DOI: 10.1016/j.jbc.2021.101228   
2021 Faria M, Domingues R, Bugalho MJ, Silva AL, Matos P. Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer. Cancers. 13. PMID 34771624 DOI: 10.3390/cancers13215460   
2021 Lee G, Leech G, Lwin P, Michel J, Currie C, Rust MJ, Ross JL, McGorty RJ, Das M, Robertson-Anderson RM. Active cytoskeletal composites display emergent tunable contractility and restructuring. Soft Matter. PMID 34792082 DOI: 10.1039/d1sm01083b   
2021 Xie Y, Zhou F, Ma Q, Lu L, Miao Y. A teamwork promotion of formin-mediated actin nucleation by Bud6 and Aip5 in . Molecular Biology of the Cell. mbcE21060285. PMID 34818061 DOI: 10.1091/mbc.E21-06-0285   
2021 Sobral AF, Chan FY, Norman MJ, Osório DS, Dias AB, Ferreira V, Barbosa DJ, Cheerambathur D, Gassmann R, Belmonte JM, Carvalho AX. Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis. Current Biology : Cb. PMID 34666005 DOI: 10.1016/j.cub.2021.09.055   
2021 Mergault C, Lisée F, Tiroille V, Magnien M, Parent C, Lenga Mabonda W, Sizaret D, Jaillet M, Crestani B, Marchand-Adam S, Plantier L. Inhibition of the Arp2/3 complex represses human lung myofibroblast differentiation and attenuates bleomycin-induced pulmonary fibrosis. British Journal of Pharmacology. PMID 34453744 DOI: 10.1111/bph.15675   
2021 Kamnev A, Palani S, Zambon P, Cheffings T, Burroughs N, Balasubramanian MK. Time-varying mobility and turnover of actomyosin ring components during cytokinesis in . Molecular Biology of the Cell. 32: 237-246. PMID 33326250 DOI: 10.1091/mbc.E20-09-0588   
2021 Beussman KM, Mollica MY, Leonard A, Miles J, Hocter J, Song Z, Stolla M, Han SJ, Emery A, Thomas WE, Sniadecki NJ. Black Dots: High-Yield Traction Force Microscopy Reveals Structural Factors Contributing to Platelet Forces. Acta Biomaterialia. PMID 34781024 DOI: 10.1016/j.actbio.2021.11.013   
2021 Zou M, Guo M, Zhou Z, Wang B, Pan Q, Li J, Zhou JM, Li J. MPK3- and MPK6-mediated VLN3 phosphorylation regulates actin dynamics during stomatal immunity in Arabidopsis. Nature Communications. 12: 6474. PMID 34753953 DOI: 10.1038/s41467-021-26827-2   
2021 de Souza LB, Ong HL, Liu X, Ambudkar IS. PIP and septin control STIM1/Orai1 assembly by regulating cytoskeletal remodeling via a CDC42-WASP/WAVE-ARP2/3 protein complex. Cell Calcium. 99: 102475. PMID 34601312 DOI: 10.1016/j.ceca.2021.102475   
2021 Kirschner A, Strat AN, Yablonski J, Yoo H, Bagué T, Li H, Zhao J, Bollinger KE, Herberg S, Ganapathy PS. Mechanosensitive channel inhibition attenuates TGFβ2-induced actin cytoskeletal remodeling and reactivity in mouse optic nerve head astrocytes. Experimental Eye Research. 212: 108791. PMID 34656548 DOI: 10.1016/j.exer.2021.108791   
2021 Lu MS, Drubin DG. Unexplored Cdc42 functions at the budding yeast nucleus suggested by subcellular localization. Small Gtpases. 1-12. PMID 34689711 DOI: 10.1080/21541248.2021.1993714   
2021 Wang Y, Xiang YY, Sugihara J, Lu WY, Liao XH, Arvan P, Refetoff S, Liu M. XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes. Thyroid : Official Journal of the American Thyroid Association. PMID 34652970 DOI: 10.1089/thy.2021.0461   
2021 Xu J, Meng X, Yang Q, Zhang J, Hu W, Fu H, Chen JW, Ma W, Chisholm AD, Sun Q, Xu S. Redox-sensitive CDC-42 clustering promotes wound closure in C. elegans. Cell Reports. 37: 110040. PMID 34818546 DOI: 10.1016/j.celrep.2021.110040   
2021 Zhang DD, Song Y, Kong P, Xu X, Gao YK, Dou YQ, Weng L, Wang XW, Lin YL, Zhang F, Zhang H, Han M. Smooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis. Cell Death & Disease. 12: 982. PMID 34686657 DOI: 10.1038/s41419-021-04239-w   
2021 Liu Y, Wu S, Jiang N, Liu W, Zhou Y, Zeng L, Zhong Q, Li Z, Fan Y. Characterization of reference genes for qRT-PCR normalization in rice-field eel (Monopterus albus) to assess differences in embryonic developmental stages, the early development of immune organs, and cells infected with rhabdovirus. Fish & Shellfish Immunology. PMID 34800657 DOI: 10.1016/j.fsi.2021.11.021