Year |
Citation |
Score |
2023 |
Zhou Q, Luo Y, Zhu Y, Chen Q, Qiu J, Cong F, Li Y, Zhang X. Nonsteroidal anti-inflammatory drugs (NSAIDs) and nucleotide analog GS-441524 conjugates with potent in vivo efficacy against coronaviruses. European Journal of Medicinal Chemistry. 249: 115113. PMID 36706621 DOI: 10.1016/j.ejmech.2023.115113 |
0.36 |
|
2023 |
Cheng H, Fu L, Yang X, Yang Y, Zhang Z, Tao Y, Wan J, Tu Z, Chen J, Li Y. Screening and identification of 3-aryl-quinolin-2-one derivatives as antiviral agents against influenza A. Journal of Medical Virology. 95: e28327. PMID 36415105 DOI: 10.1002/jmv.28327 |
0.339 |
|
2022 |
Yang Y, Yu Q, Hu L, Dai B, Qi R, Chang Y, Zhang Q, Zhang Z, Li Y, Zhang X. Enantioselective semisynthesis of novel cephalotaxine esters with potent antineoplastic activities against leukemia. European Journal of Medicinal Chemistry. 244: 114731. PMID 36242991 DOI: 10.1016/j.ejmech.2022.114731 |
0.322 |
|
2022 |
Li Y, Huang Y, Cheng H, Xu F, Qi R, Dai B, Yang Y, Tu Z, Peng L, Zhang Z. Discovery of BRAF/HDAC Dual Inhibitors Suppressing Proliferation of Human Colorectal Cancer Cells. Frontiers in Chemistry. 10: 910353. PMID 35936102 DOI: 10.3389/fchem.2022.910353 |
0.456 |
|
2020 |
Li Y, Pasunooti KK, Peng H, Li RJ, Shi WQ, Liu W, Cheng Z, Head SA, Liu JO. Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors. Acs Medicinal Chemistry Letters. 11: 1111-1117. PMID 32550989 DOI: 10.1021/Acsmedchemlett.9B00438 |
0.615 |
|
2019 |
Yang W, Li Y, Ai Y, Obianom ON, Guo D, Yang H, Sakamuru S, Xia M, Shu Y, Xue F. Pyrazole-4-Carboxamide (YW2065): A Therapeutic Candidate for Colorectal Cancer via Dual Activities of Wnt/β-Catenin Signaling Inhibition and AMP-Activated Protein Kinase (AMPK) Activation. Journal of Medicinal Chemistry. PMID 31769984 DOI: 10.1021/Acs.Jmedchem.9B01252 |
0.406 |
|
2019 |
Liu JO, Guo Z, Cheng Z, Wang J, Liu W, Peng H, Wang Y, Rao S, Li R, Ying X, Korangath P, Liberti M, Li Y, Xie Y, Hong S, et al. Discovery of a potent GLUT inhibitor using rapafucin 3D microarrays. Angewandte Chemie (International Ed. in English). PMID 31591797 DOI: 10.1002/Anie.201905578 |
0.542 |
|
2018 |
Li Y, Pasunooti KK, Li RJ, Liu W, Head SA, Shi WQ, Liu JO. Novel Tetrazole-containing Analogs of Itraconazole as Potent Anti-angiogenic Agents with Reduced CYP3A4 Inhibition. Journal of Medicinal Chemistry. PMID 30481027 DOI: 10.1021/Acs.Jmedchem.8B01252 |
0.658 |
|
2017 |
Chang Y, Lu X, Shibu MA, Dai YB, Luo J, Zhang Y, Li Y, Zhao P, Zhang Z, Xu Y, Tu ZC, Zhang Q, Yun CH, Huang CY, Ding K. Structure-Based Design of N-(3-((1H-pyrazolo[3, 4-b]pyridin-5-yl)ethynyl) Benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors. Journal of Medicinal Chemistry. PMID 28586211 DOI: 10.1021/acs.jmedchem.7b00572 |
0.41 |
|
2015 |
Chan S, Han K, Qu R, Tong L, Li Y, Zhang Z, Cheng H, Lu X, Patterson A, Smaill J, Ren X, Ding J, Xie H, Ding K. 2,4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFR(L858R/T790M). Bioorganic & Medicinal Chemistry Letters. PMID 26259806 DOI: 10.1016/J.Bmcl.2015.07.089 |
0.44 |
|
2015 |
Li Y, Cheng H, Zhang Z, Zhuang X, Luo J, Long H, Zhou Y, Xu Y, Taghipouran R, Li D, Patterson A, Smaill J, Tu Z, Wu D, Ren X, et al. N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors. Acs Medicinal Chemistry Letters. 6: 543-7. PMID 26005530 DOI: 10.1021/Acsmedchemlett.5B00039 |
0.476 |
|
2014 |
Li Y, Yu Y, Jin K, Gao L, Luo T, Sheng L, Shao X, Li J. Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 4125-8. PMID 25124112 DOI: 10.1016/j.bmcl.2014.07.055 |
0.393 |
|
2012 |
Li Y, Shen M, Zhang Z, Luo J, Pan X, Lu X, Long H, Wen D, Zhang F, Leng F, Li Y, Tu Z, Ren X, Ding K. Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant. Journal of Medicinal Chemistry. 55: 10033-46. PMID 23088644 DOI: 10.1021/jm301188x |
0.451 |
|
2011 |
Peng L, Duan L, Liu X, Shen M, Li Y, Yan J, Li H, Ding K. Structure-activity study on a series of α-glutamic acid scaffold based compounds as new ADAMTS inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 4457-61. PMID 21733683 DOI: 10.1016/j.bmcl.2011.06.009 |
0.435 |
|
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