| Year |
Citation |
Score |
| 2023 |
Zaragoza JPT, Offenbacher AR, Hu S, Gee CL, Firestein ZM, Minnetian N, Deng Z, Fan F, Iavarone AT, Klinman JP. Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211630120. PMID 36867685 DOI: 10.1073/pnas.2211630120 |
0.738 |
|
| 2019 |
Hu S, Offenbacher AR, Lu ED, Klinman JP. Comparative kinetic isotope effects on first- and second-order rate constants of soybean lipoxygenase variants uncover a substrate-binding network. The Journal of Biological Chemistry. PMID 31624150 DOI: 10.1074/Jbc.Ra119.010826 |
0.706 |
|
| 2019 |
Hu S, Offenbacher AR, Thompson EM, Gee CL, Wilcoxen J, Carr CAM, Prigozhin DM, Yang V, Alber T, Britt RD, Fraser JS, Klinman JP. Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network. Journal of the American Chemical Society. PMID 30645119 DOI: 10.1021/Jacs.8B10992 |
0.723 |
|
| 2017 |
Hu S, Soudackov AV, Hammes-Schiffer S, Klinman JP. Enhanced Rigidification within a Double Mutant of Soybean Lipoxygenase Provides Experimental Support for Vibronically Nonadiabatic Proton-Coupled Electron Transfer Models. Acs Catalysis. 7: 3569-3574. PMID 29250456 DOI: 10.1021/Acscatal.7B00688 |
0.687 |
|
| 2017 |
Klinman JP, Offenbacher AR, Hu S. Origins of Enzyme Catalysis: Experimental Findings for C-H Activation, New Models, and Their Relevance to Prevailing Theoretical Constructs. Journal of the American Chemical Society. PMID 29244501 DOI: 10.1021/Jacs.7B08418 |
0.719 |
|
| 2017 |
Offenbacher AR, Hu S, Poss EM, Carr CAM, Scouras AD, Prigozhin DM, Iavarone AT, Palla A, Alber T, Fraser JS, Klinman JP. Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling. Acs Central Science. 3: 570-579. PMID 28691068 DOI: 10.1021/Acscentsci.7B00142 |
0.741 |
|
| 2016 |
Hu S, Cattin-Ortolá J, Munos JW, Klinman JP. Hydrostatic Pressure Studies Distinguish Global from Local Protein Motions in C-H Activation by Soybean Lipoxygenase-1. Angewandte Chemie (International Ed. in English). PMID 27348724 DOI: 10.1002/Anie.201603592 |
0.659 |
|
| 2014 |
Hu S, Sharma SC, Scouras AD, Soudackov AV, Carr CA, Hammes-Schiffer S, Alber T, Klinman JP. Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation. Journal of the American Chemical Society. 136: 8157-60. PMID 24884374 DOI: 10.1021/Ja502726S |
0.736 |
|
| 2012 |
Lv J, Zhang L, Hu S, Cheng JP, Luo S. Asymmetric binary-acid catalysis with InBr3 in the inverse-electron-demanding hetero-Diels-Alder reaction of mono- and bis-substituted cyclopentadienes: remote fluoro-effect on stereocontrol. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 799-803. PMID 22170757 DOI: 10.1002/Chem.201103340 |
0.321 |
|
| 2011 |
Hu S, Zhang L, Li J, Luo S, Cheng JP. Chiral primary amine catalyzed asymmetric direct cross-aldol reaction of acetaldehyde European Journal of Organic Chemistry. 3347-3352. DOI: 10.1002/Ejoc.201100267 |
0.376 |
|
| 2010 |
Li X, Hu S, Xi Z, Zhang L, Luo S, Cheng JP. Chiral amine thiourea-promoted enantioselective Michael addition reactions of 3-substituted benzofuran-2(3H)-ones to maleimides. The Journal of Organic Chemistry. 75: 8697-700. PMID 21105671 DOI: 10.1021/Jo101832E |
0.353 |
|
| 2010 |
Hu S, Li J, Xiang J, Pan J, Luo S, Cheng JP. Asymmetric supramolecular primary amine catalysis in aqueous buffer: Connections of selective recognition and asymmetric catalysis Journal of the American Chemical Society. 132: 7216-7228. PMID 20433173 DOI: 10.1021/Ja102819G |
0.386 |
|
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