Year |
Citation |
Score |
2023 |
Johnson LA, Mart RJ, Allemann RK. A Photoresponsive Homing Endonuclease for Programmed DNA Cleavage. Acs Synthetic Biology. PMID 38061193 DOI: 10.1021/acssynbio.3c00425 |
0.694 |
|
2022 |
Allemann RK, Samperio R, Mart R, Luk L, Tsai YH, Jones A, Cruz-Samperio R. Spatio-temporal control of cell death by selective delivery of photo-activatable proteins. Chembiochem : a European Journal of Chemical Biology. PMID 35420232 DOI: 10.1002/cbic.202200115 |
0.695 |
|
2020 |
Adesina AS, Świderek K, Luk LYP, Moliner V, Allemann RK. Electric Field Measurements Reveal the Pivotal Role of Cofactor-Substrate Interaction in Dihydrofolate Reductase Catalysis. Acs Catalysis. 10: 7907-7914. PMID 32905264 DOI: 10.1021/Acscatal.0C01856 |
0.306 |
|
2020 |
Day AH, Übler MH, Best HL, Lloyd-Evans E, Mart RJ, Fallis IA, Allemann RK, Al-Wattar EAH, Keymer NI, Buurma NJ, Pope SJA. Targeted cell imaging properties of a deep red luminescent iridium(iii) complex conjugated with a c-Myc signal peptide. Chemical Science. 11: 1599-1606. PMID 32206278 DOI: 10.1039/C9Sc05568A |
0.721 |
|
2020 |
Allemann RK, Johnson L, Dunbabin A, Benton J, Mart R. Modular Chemoenzymatic Synthesis of Terpenes and their Analogues. Angewandte Chemie (International Ed. in English). PMID 32103574 DOI: 10.1002/Anie.202001744 |
0.708 |
|
2020 |
Cresser-Brown J, Rizkallah P, Jin Y, Roth C, Miller DJ, Allemann RK. An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq. Acta Crystallographica. Section F, Structural Biology Communications. 76: 81-85. PMID 32039889 DOI: 10.1107/S2053230X20001181 |
0.329 |
|
2019 |
Angelastro A, Ruiz-Pernía JJ, Tuñón I, Moliner V, Luk LYP, Allemann RK. Loss of Hyperconjugative Effects Drives Hydride Transfer during Dihydrofolate Reductase Catalysis. Acs Catalysis. 9: 10343-10349. PMID 32051770 DOI: 10.1021/Acscatal.9B02839 |
0.305 |
|
2019 |
Ruiz-Pernía JJ, Tuñón I, Moliner V, Allemann RK. Why are some Enzymes Dimers? Flexibility and Catalysis in Dihydrofolate Reductase. Acs Catalysis. 9: 5902-5911. PMID 31289693 DOI: 10.1021/Acscatal.9B01250 |
0.352 |
|
2019 |
Scott AF, Cresser-Brown J, Williams TL, Rizkallah PJ, Jin Y, Luk LY, Allemann RK. Crystal Structure and Biophysical Analysis of Furfural Detoxifying Aldehyde Reductase from . Applied and Environmental Microbiology. PMID 31101612 DOI: 10.1128/Aem.00978-19 |
0.354 |
|
2019 |
Kalvaitis M, Johnson LA, Mart RJ, Rizkallah PJ, Allemann RK. Non-canonical Chromophore Reveals Structural Rearrangements of Light-Oxygen-Voltage Domain on Photoactivation. Biochemistry. PMID 31082213 DOI: 10.1021/Acs.Biochem.9B00255 |
0.715 |
|
2019 |
Allemann RK, Scott AF, Luk LY, Tuñón I, Moliner V. Heavy enzymes and the rational redesign of protein catalysts. Chembiochem : a European Journal of Chemical Biology. PMID 31016852 DOI: 10.1002/Cbic.201900134 |
0.346 |
|
2019 |
Patel SG, Sayers EJ, He L, Narayan R, Williams TL, Mills EM, Allemann RK, Luk LYP, Jones AT, Tsai YH. Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines. Scientific Reports. 9: 6298. PMID 31000738 DOI: 10.1038/S41598-019-42456-8 |
0.333 |
|
2019 |
Loizzi M, Miller DJ, Allemann RK. Silent catalytic promiscuity in the high-fidelity terpene cyclase δ-cadinene synthase. Organic & Biomolecular Chemistry. PMID 30652178 DOI: 10.1039/C8Ob02821D |
0.316 |
|
2018 |
Kalash L, Cresser-Brown J, Habchi J, Morgan C, Miller DJ, Glen RC, Allemann RK, Bender A. Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space. European Journal of Medicinal Chemistry. 157: 1264-1275. PMID 30195237 DOI: 10.1016/J.Ejmech.2018.08.049 |
0.318 |
|
2018 |
Huynh F, Miller DJ, Allemann RK. Sesquiterpene Synthase-Catalyzed Conversion of a Farnesyl Diphosphate Analogue to a Nonnatural Terpenoid Ether. Methods in Enzymology. 608: 83-95. PMID 30173774 DOI: 10.1016/Bs.Mie.2018.05.004 |
0.326 |
|
2018 |
Allemann RK, Huynh F, Jenkins R, Grundy D, Miller DJ. Sesquiterpene Synthase Catalysed Formation of a Novel Medium Sized Cyclic Terpenoid Ether from Farnesyl Diphosphate Analogues. Chembiochem : a European Journal of Chemical Biology. PMID 29802753 DOI: 10.1002/Cbic.201800218 |
0.352 |
|
2018 |
Allemann RK, Ruiz-Pernia JJ, Luk L, Tunon I, Moliner V, Behiry E. Isotope substitution of promiscuous alcohol dehydrogenase reveals origin of substrate preference in transition state. Angewandte Chemie (International Ed. in English). PMID 29341402 DOI: 10.1002/Anie.201712826 |
0.312 |
|
2017 |
Scott AF, Luk LYP, Allemann RK. Chemical Ligation and Isotope Labeling to Locate Dynamic Effects. Methods in Enzymology. 596: 23-41. PMID 28911773 DOI: 10.1016/Bs.Mie.2017.06.040 |
0.339 |
|
2017 |
Angelastro A, Dawson WM, Luk LYP, Loveridge EJ, Allemann RK. Chemo-Enzymatic Assembly of Isotopically Labeled Folates. Journal of the American Chemical Society. PMID 28820585 DOI: 10.1021/Jacs.7B06358 |
0.32 |
|
2017 |
Hughes RL, Johnson LA, Behiry EM, Loveridge EJ, Allemann RK. A Rapid Analysis of Variations in Conformational Behavior During Dihydrofolate Reductase Catalysis. Biochemistry. PMID 28368101 DOI: 10.1021/Acs.Biochem.7B00045 |
0.378 |
|
2017 |
Loveridge EJ, Hroch L, Hughes RL, Williams T, Davies RL, Angelastro A, Luk LY, Maglia G, Allemann RK. Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima. Biochemistry. PMID 28319664 DOI: 10.1021/Acs.Biochem.6B01268 |
0.333 |
|
2017 |
Demiray M, Tang X, Wirth T, Faraldos JA, Allemann RK. An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde. Angewandte Chemie (International Ed. in English). PMID 28294491 DOI: 10.1002/Anie.201609557 |
0.305 |
|
2017 |
Angelastro A, Dawson WM, Luk LYP, Allemann RK. A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number Acs Catalysis. 7: 1025-1029. DOI: 10.1021/Acscatal.6B03061 |
0.301 |
|
2016 |
Ruiz-Pernía JJ, Behiry E, Luk LYP, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Minimization of dynamic effects in the evolution of dihydrofolate reductase. Chemical Science. 7: 3248-3255. PMID 29997817 DOI: 10.1039/C5Sc04209G |
0.324 |
|
2016 |
Loveridge EJ, Allemann RK. Pinpointing dynamic coupling in enzymes for efficient drug design. Future Science Oa. 2: FSO95. PMID 28031945 DOI: 10.4155/Fsoa.2015.0017 |
0.311 |
|
2016 |
Faraldos JA, Grundy DJ, Cascon O, Leoni S, van der Kamp MW, Allemann RK. Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate. Chemical Communications (Cambridge, England). PMID 27853760 DOI: 10.1039/C6Cc08164A |
0.351 |
|
2016 |
Mart RJ, Allemann RK. Azobenzene photocontrol of peptides and proteins. Chemical Communications (Cambridge, England). 52: 12262-12277. PMID 27541361 DOI: 10.1039/C6Cc04004G |
0.706 |
|
2016 |
Chen M, Chou WK, Al-Lami N, Faraldos JA, Allemann RK, Cane DE, Christianson DW. Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry. PMID 27172425 DOI: 10.1021/Acs.Biochem.6B00343 |
0.304 |
|
2016 |
Grundy DJ, Chen M, González V, Leoni S, Miller DJ, Christianson DW, Allemann RK. Mechanism of Germacradien-4-ol Synthase-Controlled Water Capture. Biochemistry. 55: 2112-21. PMID 26998816 DOI: 10.1021/Acs.Biochem.6B00115 |
0.338 |
|
2016 |
Mart RJ, Meah D, Allemann RK. Photocontrolled Exposure of Pro-apoptotic Peptide Sequences in LOV Proteins Modulates Bcl-2 Family Interactions. Chembiochem : a European Journal of Chemical Biology. 17: 698-701. PMID 26493687 DOI: 10.1002/Cbic.201500469 |
0.719 |
|
2015 |
Adams SE, Robinson EJ, Miller DJ, Rizkallah PJ, Hallett MB, Allemann RK. Conformationally restricted calpain inhibitors. Chemical Science. 6: 6865-6871. PMID 28757975 DOI: 10.1039/C5Sc01158B |
0.302 |
|
2015 |
Luk LY, Ruiz-Pernía JJ, Adesina AS, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Chemical Ligation and Isotope Labeling to Locate Dynamic Effects during Catalysis by Dihydrofolate Reductase. Angewandte Chemie (International Ed. in English). 54: 9016-20. PMID 26079622 DOI: 10.1002/Anie.201503968 |
0.312 |
|
2015 |
Luk LY, Loveridge EJ, Allemann RK. Protein motions and dynamic effects in enzyme catalysis. Physical Chemistry Chemical Physics : Pccp. 17: 30817-27. PMID 25854702 DOI: 10.1039/C5Cp00794A |
0.325 |
|
2014 |
Luk LY, Ruiz-Pernía JJ, Dawson WM, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Protein isotope effects in dihydrofolate reductase from Geobacillus stearothermophilus show entropic-enthalpic compensatory effects on the rate constant. Journal of the American Chemical Society. 136: 17317-23. PMID 25396728 DOI: 10.1021/Ja5102536 |
0.323 |
|
2014 |
Gonzalez V, Touchet S, Grundy DJ, Faraldos JA, Allemann RK. Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-germacrene A synthase. Journal of the American Chemical Society. 136: 14505-12. PMID 25230152 DOI: 10.1021/Ja5066366 |
0.34 |
|
2014 |
Adams SE, Rizkallah PJ, Miller DJ, Robinson EJ, Hallett MB, Allemann RK. The structural basis of differential inhibition of human calpain by indole and phenyl α-mercaptoacrylic acids. Journal of Structural Biology. 187: 236-41. PMID 25086406 DOI: 10.1016/J.Jsb.2014.07.004 |
0.307 |
|
2014 |
Behiry EM, Luk LY, Matthews SM, Loveridge EJ, Allemann RK. Role of the occluded conformation in bacterial dihydrofolate reductases. Biochemistry. 53: 4761-8. PMID 25014833 DOI: 10.1021/Bi500507V |
0.342 |
|
2014 |
Behiry EM, Evans RM, Guo J, Loveridge EJ, Allemann RK. Loop interactions during catalysis by dihydrofolate reductase from Moritella profunda. Biochemistry. 53: 4769-74. PMID 25014120 DOI: 10.1021/Bi500508Z |
0.335 |
|
2014 |
Luk LY, Loveridge EJ, Allemann RK. Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases. Journal of the American Chemical Society. 136: 6862-5. PMID 24779446 DOI: 10.1021/Ja502673H |
0.338 |
|
2013 |
Ruiz-Pernia JJ, Luk LY, GarcÃa-Meseguer R, Martà S, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society. 135: 18689-96. PMID 24252106 DOI: 10.1021/Ja410519H |
0.337 |
|
2013 |
van der Kamp MW, Sirirak J, Żurek J, Allemann RK, Mulholland AJ. Conformational change and ligand binding in the aristolochene synthase catalytic cycle. Biochemistry. 52: 8094-105. PMID 24106830 DOI: 10.1021/Bi400898K |
0.348 |
|
2013 |
Luk LY, Javier Ruiz-PernÃa J, Dawson WM, Roca M, Loveridge EJ, Glowacki DR, Harvey JN, Mulholland AJ, Tuñón I, Moliner V, Allemann RK. Unraveling the role of protein dynamics in dihydrofolate reductase catalysis. Proceedings of the National Academy of Sciences of the United States of America. 110: 16344-9. PMID 24065822 DOI: 10.1073/Pnas.1312437110 |
0.344 |
|
2013 |
Mart RJ, Errington RJ, Watkins CL, Chappell SC, Wiltshire M, Jones AT, Smith PJ, Allemann RK. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular Biosystems. 9: 2597-603. PMID 23942570 DOI: 10.1039/C3Mb70246D |
0.737 |
|
2013 |
Chen M, Al-lami N, Janvier M, D'Antonio EL, Faraldos JA, Cane DE, Allemann RK, Christianson DW. Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry. 52: 5441-53. PMID 23905850 DOI: 10.1021/Bi400691V |
0.364 |
|
2013 |
Guo J, Loveridge EJ, Luk LY, Allemann RK. Effect of dimerization on dihydrofolate reductase catalysis. Biochemistry. 52: 3881-7. PMID 23672258 DOI: 10.1021/Bi4005073 |
0.341 |
|
2013 |
Li JX, Fang X, Zhao Q, Ruan JX, Yang CQ, Wang LJ, Miller DJ, Faraldos JA, Allemann RK, Chen XY, Zhang P. Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. The Biochemical Journal. 451: 417-26. PMID 23438177 DOI: 10.1042/Bj20130041 |
0.355 |
|
2013 |
Wysoczanski P, Mart RJ, Loveridge EJ, Williams C, Whittaker SB, Crump MP, Allemann RK. ¹H, ¹³C and ¹âµN chemical shift assignments of unliganded Bcl-xL and its complex with a photoresponsive Bak-derived peptide. Biomolecular Nmr Assignments. 7: 187-91. PMID 22744789 DOI: 10.1007/S12104-012-9407-9 |
0.729 |
|
2012 |
Faraldos JA, Gonzalez V, Li A, Yu F, Köksal M, Christianson DW, Allemann RK. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. Journal of the American Chemical Society. 134: 20844-8. PMID 23214943 DOI: 10.1021/Ja311022S |
0.325 |
|
2012 |
Wysoczanski P, Mart RJ, Loveridge EJ, Williams C, Whittaker SB, Crump MP, Allemann RK. NMR solution structure of a photoswitchable apoptosis activating Bak peptide bound to Bcl-xL. Journal of the American Chemical Society. 134: 7644-7. PMID 22515821 DOI: 10.1021/Ja302390A |
0.739 |
|
2012 |
Loveridge EJ, Behiry EM, Guo J, Allemann RK. Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis. Nature Chemistry. 4: 292-7. PMID 22437714 DOI: 10.1038/Nchem.1296 |
0.355 |
|
2012 |
Mart RJ, Wysoczański P, Kneissl S, Ricci A, Brancale A, Allemann RK. Design of photocontrolled RNA-binding peptidomimetics. Chembiochem : a European Journal of Chemical Biology. 13: 515-9. PMID 22302640 DOI: 10.1002/Cbic.201100800 |
0.702 |
|
2012 |
Miller DJ, Allemann RK. Sesquiterpene synthases: passive catalysts or active players? Natural Product Reports. 29: 60-71. PMID 22068697 DOI: 10.1039/C1Np00060H |
0.335 |
|
2012 |
Wysoczanski P, Mart R, Loveridge J, Williams C, Whittaker S, Crump M, Allemann R. NMR STRUCTURE of Bcl-XL Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lpc/Pdb |
0.694 |
|
2012 |
Wysoczanski P, Mart R, Loveridge J, Williams C, Whittaker S, Crump M, Allemann R. SOLUTION STRUCTURE OF AN APOPTOSIS ACTIVATING PHOTOSWITCHABLE BAK PEPTIDE BOUND to BCL-XL Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lp8/Pdb |
0.719 |
|
2011 |
Loveridge EJ, Tey LH, Behiry EM, Dawson WM, Evans RM, Whittaker SB, Günther UL, Williams C, Crump MP, Allemann RK. The role of large-scale motions in catalysis by dihydrofolate reductase. Journal of the American Chemical Society. 133: 20561-70. PMID 22060818 DOI: 10.1021/Ja208844J |
0.336 |
|
2011 |
Faraldos JA, González V, Senske M, Allemann RK. Templating effects in aristolochene synthase catalysis: elimination versus cyclisation. Organic & Biomolecular Chemistry. 9: 6920-3. PMID 21870004 DOI: 10.1039/C1Ob06184D |
0.302 |
|
2011 |
Fricke T, Mart RJ, Watkins CL, Wiltshire M, Errington RJ, Smith PJ, Jones AT, Allemann RK. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry. 22: 1763-7. PMID 21823633 DOI: 10.1021/Bc200338U |
0.729 |
|
2011 |
Faraldos JA, Antonczak AK, González V, Fullerton R, Tippmann EM, Allemann RK. Probing eudesmane cation-π interactions in catalysis by aristolochene synthase with non-canonical amino acids. Journal of the American Chemical Society. 133: 13906-9. PMID 21815676 DOI: 10.1021/Ja205927U |
0.32 |
|
2010 |
Edwards WR, Williams AJ, Morris JL, Baldwin AJ, Allemann RK, Jones DD. Regulation of beta-lactamase activity by remote binding of heme: functional coupling of unrelated proteins through domain insertion. Biochemistry. 49: 6541-9. PMID 20602528 DOI: 10.1021/Bi100793Y |
0.346 |
|
2010 |
Loveridge EJ, Allemann RK. The temperature dependence of the kinetic isotope effects of dihydrofolate reductase from Thermotoga maritima is influenced by intersubunit interactions. Biochemistry. 49: 5390-6. PMID 20515024 DOI: 10.1021/Bi100761X |
0.342 |
|
2010 |
Tey LH, Loveridge EJ, Swanwick RS, Flitsch SL, Allemann RK. Highly site-selective stability increases by glycosylation of dihydrofolate reductase. The Febs Journal. 277: 2171-9. PMID 20412060 DOI: 10.1111/J.1742-4658.2010.07634.X |
0.331 |
|
2010 |
Faraldos JA, Kariuki B, Allemann RK. Intermediacy of eudesmane cation during catalysis by aristolochene synthase. The Journal of Organic Chemistry. 75: 1119-25. PMID 20095558 DOI: 10.1021/Jo902397V |
0.359 |
|
2010 |
Loveridge EJ, Tey LH, Allemann RK. Solvent effects on catalysis by Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society. 132: 1137-43. PMID 20047317 DOI: 10.1021/Ja909353C |
0.333 |
|
2010 |
Fricke T, Mart RJ, Watkins CL, Jones AT, Allemann RK. Click chemistry for the generation of cell permeable apoptotic peptides Drug Discovery Today. 15: 1088-1088. DOI: 10.1016/J.Drudis.2010.09.375 |
0.732 |
|
2009 |
Loveridge EJ, Maglia G, Allemann RK. The role of arginine 28 in catalysis by dihydrofolate reductase from the hyperthermophile Thermotoga maritima. Chembiochem : a European Journal of Chemical Biology. 10: 2624-7. PMID 19816891 DOI: 10.1002/Cbic.200900465 |
0.334 |
|
2009 |
Gennadios HA, Gonzalez V, Di Costanzo L, Li A, Yu F, Miller DJ, Allemann RK, Christianson DW. Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry. 48: 6175-83. PMID 19489610 DOI: 10.1021/Bi900483B |
0.307 |
|
2009 |
Loveridge EJ, Rodriguez RJ, Swanwick RS, Allemann RK. Effect of dimerization on the stability and catalytic activity of dihydrofolate reductase from the hyperthermophile Thermotoga maritima. Biochemistry. 48: 5922-33. PMID 19453185 DOI: 10.1021/Bi900411A |
0.32 |
|
2009 |
Loveridge EJ, Behiry EM, Swanwick RS, Allemann RK. Different reaction mechanisms for mesophilic and thermophilic dihydrofolate reductases. Journal of the American Chemical Society. 131: 6926-7. PMID 19419144 DOI: 10.1021/Ja901441K |
0.337 |
|
2009 |
Allemann RK, Evans RM, Loveridge EJ. Probing coupled motions in enzymatic hydrogen tunnelling reactions. Biochemical Society Transactions. 37: 349-53. PMID 19290860 DOI: 10.1042/Bst0370349 |
0.364 |
|
2009 |
Miller DJ, Yu F, Knight DW, Allemann RK. 6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase. Organic & Biomolecular Chemistry. 7: 962-75. PMID 19225680 DOI: 10.1039/B817194G |
0.326 |
|
2008 |
Kneissl S, Loveridge EJ, Williams C, Crump MP, Allemann RK. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL. Chembiochem : a European Journal of Chemical Biology. 9: 3046-54. PMID 19012295 DOI: 10.1002/Cbic.200800502 |
0.402 |
|
2008 |
Miller DJ, Gao J, Truhlar DG, Young NJ, Gonzalez V, Allemann RK. Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti. Organic & Biomolecular Chemistry. 6: 2346-54. PMID 18563268 DOI: 10.1039/B804198A |
0.307 |
|
2008 |
Edwards WR, Busse K, Allemann RK, Jones DD. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Research. 36: e78. PMID 18559359 DOI: 10.1093/Nar/Gkn363 |
0.325 |
|
2008 |
Shishova EY, Yu F, Miller DJ, Faraldos JA, Zhao Y, Coates RM, Allemann RK, Cane DE, Christianson DW. X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. The Journal of Biological Chemistry. 283: 15431-9. PMID 18385128 DOI: 10.1074/Jbc.M800659200 |
0.339 |
|
2008 |
Allemann RK. Chemical wizardry? The generation of diversity in terpenoid biosynthesis Pure and Applied Chemistry. 80: 1791-1798. DOI: 10.1351/Pac200880081791 |
0.345 |
|
2007 |
Allemann RK, Young NJ, Ma S, Truhlar DG, Gao J. Synthetic efficiency in enzyme mechanisms involving carbocations: aristolochene synthase. Journal of the American Chemical Society. 129: 13008-13. PMID 17918834 DOI: 10.1021/Ja0722067 |
0.344 |
|
2007 |
Miller DJ, Yu F, Young NJ, Allemann RK. Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity. Organic & Biomolecular Chemistry. 5: 3287-98. PMID 17912381 DOI: 10.1039/B713301B |
0.361 |
|
2007 |
Miller DJ, Yu F, Allemann RK. Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A. Chembiochem : a European Journal of Chemical Biology. 8: 1819-25. PMID 17683054 DOI: 10.1002/Cbic.200700219 |
0.314 |
|
2007 |
Pang J, Allemann RK. Molecular dynamics simulation of thermal unfolding of Thermatoga maritima DHFR Physical Chemistry Chemical Physics. 9: 711-718. PMID 17268682 DOI: 10.1039/B611210B |
0.333 |
|
2006 |
Allemann RK, Evans RM, Tey LH, Maglia G, Pang J, Rodriguez R, Shrimpton PJ, Swanwick RS. Protein motions during catalysis by dihydrofolate reductases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 1317-21. PMID 16873119 DOI: 10.1098/Rstb.2006.1865 |
0.343 |
|
2006 |
Nicoll AJ, Miller DJ, Fütterer K, Ravelli R, Allemann RK. Designed high affinity Cu2+-binding alpha-helical foldamer. Journal of the American Chemical Society. 128: 9187-93. PMID 16834392 DOI: 10.1021/Ja061513U |
0.377 |
|
2006 |
Forcat S, Allemann RK. Stabilisation of transition states prior to and following eudesmane cation in aristolochene synthase. Organic & Biomolecular Chemistry. 4: 2563-7. PMID 16791319 DOI: 10.1039/B604147G |
0.337 |
|
2006 |
Pang J, Pu J, Gao J, Truhlar DG, Allemann RK. Hydride transfer reaction catalyzed by hyperthermophilic dihydrofolate reductase is dominated by quantum mechanical tunneling and is promoted by both inter- and intramonomeric correlated motions. Journal of the American Chemical Society. 128: 8015-23. PMID 16771517 DOI: 10.1021/Ja061585L |
0.303 |
|
2006 |
Swanwick RS, Maglia G, Tey LH, Allemann RK. Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase. The Biochemical Journal. 394: 259-65. PMID 16241906 DOI: 10.1042/Bj20051464 |
0.33 |
|
2005 |
Nicoll AJ, Weston CJ, Cureton C, Ludwig C, Dancea F, Spencer N, Smart OS, Günther UL, Allemann RK. De novo design of a stable N-terminal helical foldamer. Organic & Biomolecular Chemistry. 3: 4310-5. PMID 16327890 DOI: 10.1039/B513891D |
0.383 |
|
2005 |
Guerrero L, Smart OS, Woolley GA, Allemann RK. Photocontrol of DNA binding specificity of a miniature engrailed homeodomain. Journal of the American Chemical Society. 127: 15624-9. PMID 16262429 DOI: 10.1021/Ja0550428 |
0.351 |
|
2005 |
Swanwick RS, Daines AM, Flitsch SL, Allemann RK. Synthesis of homogenous site-selectively glycosylated proteins. Organic & Biomolecular Chemistry. 3: 572-4. PMID 15703788 DOI: 10.1039/B417133K |
0.303 |
|
2004 |
Weston CJ, Cureton CH, Calvert MJ, Smart OS, Allemann RK. A stable miniature protein with oxaloacetate decarboxylase activity. Chembiochem : a European Journal of Chemical Biology. 5: 1075-80. PMID 15300830 DOI: 10.1002/Cbic.200300805 |
0.418 |
|
2004 |
Nicoll AJ, Allemann RK. Nucleophilic and general acid catalysis at physiological pH by a designed miniature esterase. Organic & Biomolecular Chemistry. 2: 2175-80. PMID 15280952 DOI: 10.1039/B404730C |
0.384 |
|
2004 |
Turner EC, Cureton CH, Weston CJ, Smart OS, Allemann RK. Controlling the DNA binding specificity of bHLH proteins through intramolecular interactions. Chemistry & Biology. 11: 69-77. PMID 15112996 DOI: 10.1016/J.Chembiol.2003.12.015 |
0.348 |
|
2004 |
Swanwick RS, Shrimpton PJ, Allemann RK. Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished catalytic performance. Biochemistry. 43: 4119-27. PMID 15065854 DOI: 10.1021/Bi036164K |
0.36 |
|
2003 |
Deligeorgopoulou A, Allemann RK. Evidence for differential folding of farnesyl pyrophosphate in the active site of aristolochene synthase: a single-point mutation converts aristolochene synthase into an (E)-beta-farnesene synthase. Biochemistry. 42: 7741-7. PMID 12820883 DOI: 10.1021/Bi034410M |
0.332 |
|
2003 |
Maglia G, Javed MH, Allemann RK. Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima. The Biochemical Journal. 374: 529-35. PMID 12765545 DOI: 10.1042/Bj20030412 |
0.311 |
|
2003 |
Shrimpton P, Mullaney A, Allemann RK. Functional role for Tyr 31 in the catalytic cycle of chicken dihydrofolate reductase. Proteins. 51: 216-23. PMID 12660990 DOI: 10.1002/Prot.10370 |
0.331 |
|
2002 |
Calvert MJ, Ashton PR, Allemann RK. Germacrene A is a product of the aristolochene synthase-mediated conversion of farnesylpyrophosphate to aristolochene. Journal of the American Chemical Society. 124: 11636-41. PMID 12296728 DOI: 10.1021/Ja020762P |
0.306 |
|
2002 |
Shrimpton P, Allemann RK. Role of water in the catalytic cycle of E. coli dihydrofolate reductase. Protein Science : a Publication of the Protein Society. 11: 1442-51. PMID 12021443 DOI: 10.1110/Ps.5060102 |
0.323 |
|
2002 |
Taylor SE, Rutherford TJ, Allemann RK. Design of a folded, conformationally stable oxaloacetate decarboxylase Journal of the Chemical Society-Perkin Transactions 1. 751-755. DOI: 10.1039/B200057C |
0.364 |
|
2001 |
Taylor SE, Rutherford TJ, Allemann RK. Design, synthesis and characterisation of a peptide with oxaloacetate decarboxylase activity. Bioorganic & Medicinal Chemistry Letters. 11: 2631-2635. PMID 11551766 DOI: 10.1016/S0960-894X(01)00519-4 |
0.399 |
|
2000 |
Sieber M, Allemann RK. Thermodynamics of DNA binding of MM17, a 'single chain dimer' of transcription factor MASH-1. Nucleic Acids Research. 28: 2122-2127. PMID 10773081 DOI: 10.1093/Nar/28.10.2122 |
0.331 |
|
1999 |
Dezan C, Meierhans D, Künne AGE, Allemann RK. Acquisition of myogenic specificity through replacement of one amino acid of MASH-1 and introduction of an additional alpha-helical turn. Biological Chemistry. 380: 705-710. PMID 10430036 DOI: 10.1515/Bc.1999.088 |
0.331 |
|
1998 |
Meierhans D, Allemann RK. The N-terminal Methionine Is a Major Determinant of the DNA Binding Specificity of MEF-2C Journal of Biological Chemistry. 273: 26052-26060. PMID 9748284 DOI: 10.1074/Jbc.273.40.26052 |
0.307 |
|
1998 |
Künne AGE, Sieber M, Meierhans D, Allemann RK. Thermodynamics of the DNA binding reaction of transcription factor MASH-1 Biochemistry. 37: 4217-4223. PMID 9521744 DOI: 10.1021/Bi9725374 |
0.331 |
|
1998 |
Sieber M, Allemann RK. Single chain dimers of MASH-1 bind DNA with enhanced affinity Nucleic Acids Research. 26: 1408-1413. PMID 9490785 DOI: 10.1093/Nar/26.6.1408 |
0.334 |
|
1997 |
Meierhans D, Allemann RK. High Level Expression in Soluble Form, One Step Purification, and Characterization of the DNA Binding Domain of MEF-2C Protein Expression and Purification. 11: 297-303. PMID 9425635 DOI: 10.1006/Prep.1997.0795 |
0.33 |
|
1997 |
Künne AGE, Allemann RK. Covalently linking BHLH subunits of MASH-1 increases specificity of DNA binding. Biochemistry. 36: 1085-1091. PMID 9033398 DOI: 10.1021/Bi962185L |
0.333 |
|
1996 |
Künne AGE, Meierhans D, Allemann RK. Basic helix-loop-helix protein MyoD displays modest DNA binding specificity. Febs Letters. 391: 79-83. PMID 8706935 DOI: 10.1016/0014-5793(96)00707-7 |
0.31 |
|
1995 |
Meierhan D, el-Ariss C, Neuenschwander M, Sieber M, Stackhouse JF, Allemann RK. DNA binding specificity of the basic-helix-loop-helix protein MASH-1. Biochemistry. 34: 11026-36. PMID 7669760 DOI: 10.1021/Bi00035A008 |
0.323 |
|
1993 |
Johnsson K, Allemann RK, Widmer H, Benner SA. Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides Nature. 365: 530-532. PMID 8413606 DOI: 10.1038/365530A0 |
0.669 |
|
1991 |
Allemann RK, Presnell SR, Benner SA. A hybrid of bovine pancreatic ribonuclease and human angiogenin: An external loop as a module controlling substrate specificity? Protein Engineering, Design and Selection. 4: 831-835. PMID 1798706 DOI: 10.1093/Protein/4.7.831 |
0.546 |
|
1989 |
Benner SA, Allemann RK. The return of pancreatic ribonucleases Trends in Biochemical Sciences. 14: 396-397. PMID 2479128 DOI: 10.1016/0968-0004(89)90282-X |
0.473 |
|
1988 |
Allemann RK, Hung R, Benner SA. Stereochemical profile of the dehydrogenases of Drosophila melanogaster Journal of the American Chemical Society. 110: 5555-5560. DOI: 10.1021/Ja00224A046 |
0.492 |
|
1987 |
Benner SA, Allemann RK, Ellington AD, Ge L, Glasfeld A, Leanz GF, Krauch T, MacPherson LJ, Moroney S, Piccirilli JA. Natural selection, protein engineering, and the last riboorganism: rational model building in biochemistry. Cold Spring Harbor Symposia On Quantitative Biology. 52: 53-63. PMID 2456885 DOI: 10.1101/Sqb.1987.052.01.009 |
0.748 |
|
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