☰

Weidong Xiao, PhD - Publications

Affiliations: 
Temple University, Philadelphia, PA, United States 
Tree Info Similar researchers PubMed Report error

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang J, Frabutt DA, Chrzanowski M, Li N, Miller LM, Tian J, Mulcrone PL, Lam AK, Draper BE, Jarrold MF, Herzog RW, Xiao W. A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR. Molecular Therapy. Methods & Clinical Development. 32: 101206. PMID 38390555 DOI: 10.1016/j.omtm.2024.101206  0.33
2023 Lam AK, Mulcrone PL, Frabutt D, Zhang J, Chrzanowski M, Arisa S, Munoz M, Li X, Biswas M, Markusic D, Herzog RW, Xiao W. Comprehensive Comparison of AAV Purification Methods: Iodixanol Gradient Centrifugation vs. Immuno-Affinity Chromatography. Advances in Cell and Gene Therapy. 2023. PMID 38130431 DOI: 10.1155/2023/2339702  0.304
2018 Xiao W, Gao G, Ling C, Herzog RW, Xiao X, Samulski RJ. Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates. Nature Medicine. PMID 29867233 DOI: 10.1038/S41591-018-0062-2  0.324
2017 Wang Q, Wu Z, Zhang J, Firrman J, Wei H, Zhuang Z, Liu L, Miao L, Hu Y, Li D, Diao Y, Xiao W. A Robust System for Production of Superabundant VP1 Recombinant AAV Vectors. Molecular Therapy. Methods & Clinical Development. 7: 146-156. PMID 29255740 DOI: 10.1016/J.Omtm.2017.11.002  0.337
2017 Yin C, Zhang T, Qu X, Zhang Y, Putatunda R, Xiao X, Li F, Xiao W, Zhao H, Dai S, Qin X, Mo X, Young WB, Khalili K, Hu W. In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28366764 DOI: 10.1016/J.Ymthe.2017.03.012  0.344
2015 Moore AR, Dong B, Chen L, Xiao W. Vaccinia virus as a subhelper for AAV replication and packaging. Molecular Therapy. Methods & Clinical Development. 2: 15044. PMID 26636113 DOI: 10.1038/mtm.2015.44  0.301
2014 Wang Q, Dong B, Firrman J, Roberts S, Moore AR, Cao W, Diao Y, Kapranov P, Xu R, Xiao W. Efficient production of dual recombinant adeno-associated viral vectors for factor VIII delivery. Human Gene Therapy Methods. 25: 261-8. PMID 25093498 DOI: 10.1089/Hgtb.2014.093  0.354
2013 Dong B, Moore AR, Dai J, Roberts S, Chu K, Kapranov P, Moss B, Xiao W. A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy. Nucleic Acids Research. 41: 6609-17. PMID 23677609 DOI: 10.1093/Nar/Gkt404  0.335
2011 Diao Y, Wang Q, Xiao W, Xu R. [Recombinant adeno-associated virus vector related impurities]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 27: 717-23. PMID 21845838  0.318
2011 Lu H, Qu G, Yang X, Xu R, Xiao W. Systemic elimination of de novo capsid protein synthesis from replication-competent AAV contamination in the liver. Human Gene Therapy. 22: 625-32. PMID 21244243 DOI: 10.1089/Hum.2011.005  0.407
2010 Dong B, Nakai H, Xiao W. Characterization of genome integrity for oversized recombinant AAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 87-92. PMID 19904236 DOI: 10.1038/mt.2009.258  0.308
2009 Lü Y, Wang Q, Xiao W, Diao Y, Xu R. [Trends in development of self-complementary adeno-associated virus vector]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 25: 658-64. PMID 19670632  0.326
2009 Chen L, Lu H, Wang J, Sarkar R, Yang X, Wang H, High KA, Xiao W. Enhanced factor VIII heavy chain for gene therapy of hemophilia A. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 417-24. PMID 19127250 DOI: 10.1038/Mt.2008.292  0.412
2008 Lu H, Chen L, Wang J, Huack B, Sarkar R, Zhou S, Xu R, Ding Q, Wang X, Wang H, Xiao W. Complete correction of hemophilia A with adeno-associated viral vectors containing a full-size expression cassette. Human Gene Therapy. 19: 648-54. PMID 18500941 DOI: 10.1089/Hum.2007.0182  0.444
2008 Li H, Li X, Lam KS, Tam S, Xiao W, Xu R. Adeno-associated virus-mediated pancreatic and duodenal homeobox gene-1 expression enhanced differentiation of hepatic oval stem cells to insulin-producing cells in diabetic rats. Journal of Biomedical Science. 15: 487-97. PMID 18253862 DOI: 10.1007/S11373-008-9233-3  0.307
2007 Wang J, Xie J, Lu H, Chen L, Hauck B, Samulski RJ, Xiao W. Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction. Proceedings of the National Academy of Sciences of the United States of America. 104: 13104-9. PMID 17664425 DOI: 10.1073/Pnas.0702778104  0.446
2007 Chen L, Zhu F, Li J, Lu H, Jiang H, Sarkar R, Arruda VR, Wang J, Zhao J, Pierce GF, Ding Q, Wang X, Wang H, Pipe SW, Liu XQ, ... ... Xiao W, et al. The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1856-62. PMID 17653101 DOI: 10.1038/Sj.Mt.6300268  0.47
2006 Hauck B, Xu RR, Xie J, Wu W, Ding Q, Sipler M, Wang H, Chen L, Wright JF, Xiao W. Efficient AAV1-AAV2 hybrid vector for gene therapy of hemophilia. Human Gene Therapy. 17: 46-54. PMID 16409124 DOI: 10.1089/Hum.2006.17.46  0.443
2006 Schuettrumpf J, Zou J, Zhang Y, Schlachterman A, Liu YL, Edmonson S, Xiao W, Arruda VR. The inhibitory effects of anticoagulation on in vivo gene transfer by adeno-associated viral or adenoviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 88-97. PMID 16230049 DOI: 10.1016/J.Ymthe.2005.08.004  0.414
2006 Chen L, Li J, Lu H, Jiang H, Sarkar R, Wang J, Arruda V, Pierce G, Pipe S, Liu P, Xiao X, Camire R, Xiao W. An Essential Role of the Factor VIII Light Chain in Facilitating Heavy Chain Secretion. Blood. 108: 4034-4034. DOI: 10.1182/Blood.V108.11.4034.4034  0.404
2006 Chen L, Lu H, Li J, Jiang H, Sarkar R, Pierce G, Camira R, Arruda V, Xiao X, Xiao W. 857. Molecular Engineering of Factor VIII for rAAV Delivery Molecular Therapy. 13: S330. DOI: 10.1016/J.Ymthe.2006.08.943  0.481
2005 Hauck B, Xu R, Xie J, Ding Q, Wu W, Sipler M, Wang H, High K, Xiao W. 605. Efficient AAV 1 and AAV2 Hybrid Vector for Gene Therapy of Hemophilia Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.145  0.441
2005 Hauck B, Xie J, Xiao W. 505. Analysis of AAV Genome Conversion and Stabilization Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.045  0.37
2004 Harrop JS, Poulsen DJ, Xiao W, Freese A, During MJ. Effect of altering titer, serotype, and promoter in recombinant adenoassociate virus gene therapy expression of spinal cord neurons and astrocytes. Spine. 29: 2787-92. PMID 15599280 DOI: 10.1097/01.Brs.0000147909.59083.Da  0.366
2004 Hauck B, Zhao W, High K, Xiao W. Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adeno-associated virus transduction. Journal of Virology. 78: 13678-86. PMID 15564477 DOI: 10.1128/Jvi.78.24.13678-13686.2004  0.341
2004 Arruda VR, Schuettrumpf J, Herzog RW, Nichols TC, Robinson N, Lotfi Y, Mingozzi F, Xiao W, Couto LB, High KA. Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1. Blood. 103: 85-92. PMID 12969984 DOI: 10.1182/Blood-2003-05-1446  0.41
2004 Xu RA, Sun K, Krissansen GW, Fung PW, Xu S, Xiao W, Shi J, Fan S. 625. AAV Gene Therapy for Liver Metastatic Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.549  0.358
2004 Hauck B, Zhao W, Xiao W. 747. Direct Labeling and Tracking of Adeno-Associated Virus Single Stranded DNA in AAV Transduction Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.1012  0.342
2003 Gao G, Zhou X, Alvira MR, Tran P, Marsh J, Lynd K, Xiao W, Wilson JM. High throughput creation of recombinant adenovirus vectors by direct cloning, green-white selection and I-Sce I-mediated rescue of circular adenovirus plasmids in 293 cells. Gene Therapy. 10: 1926-30. PMID 14502222 DOI: 10.1038/Sj.Gt.3302088  0.514
2003 Xu R, Sun X, Tse LY, Li H, Chan PC, Xu S, Xiao W, Kung HF, Krissansen GW, Fan ST. Long-term expression of angiostatin suppresses metastatic liver cancer in mice. Hepatology (Baltimore, Md.). 37: 1451-60. PMID 12774025 DOI: 10.1053/Jhep.2003.50244  0.335
2003 Hauck B, Chen L, Xiao W. Generation and characterization of chimeric recombinant AAV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 419-25. PMID 12668138 DOI: 10.1016/S1525-0016(03)00012-1  0.437
2003 Hauck B, Xiao W. Characterization of tissue tropism determinants of adeno-associated virus type 1. Journal of Virology. 77: 2768-74. PMID 12552020 DOI: 10.1128/Jvi.77.4.2768-2774.2003  0.374
2003 Liu Y-, Wagner K, Robinson N, Sabatino D, Margaritis P, Xiao W, Herzog RW. Optimized production of high-titer recombinant adeno-associated virus in roller bottles. Biotechniques. 34: 184-189. PMID 12545558 DOI: 10.2144/03341Dd07  0.384
2002 Mingozzi F, Schüttrumpf J, Arruda VR, Liu Y, Liu YL, High KA, Xiao W, Herzog RW. Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector. Journal of Virology. 76: 10497-502. PMID 12239326 DOI: 10.1128/Jvi.76.20.10497-10502.2002  0.433
2002 Cao L, During M, Xiao W. Replication competent helper functions for recombinant AAV vector generation. Gene Therapy. 9: 1199-206. PMID 12215886 DOI: 10.1038/Sj.Gt.3301710  0.424
2002 Rabinowitz JE, Rolling F, Li C, Conrath H, Xiao W, Xiao X, Samulski RJ. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. Journal of Virology. 76: 791-801. PMID 11752169 DOI: 10.1128/Jvi.76.2.791-801.2002  0.536
2000 Cao L, Liu Y, During MJ, Xiao W. High-titer, wild-type free recombinant adeno-associated virus vector production using intron-containing helper plasmids. Journal of Virology. 74: 11456-63. PMID 11090141 DOI: 10.1128/Jvi.74.24.11456-11463.2000  0.454
2000 Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, Flotte T, Muzyczka N. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. Journal of Virology. 74: 8635-47. PMID 10954565 DOI: 10.1128/Jvi.74.18.8635-8647.2000  0.552
2000 Xiao W, Chirmule N, Schnell MA, Tazelaar J, Hughes JV, Wilson JM. Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 323-9. PMID 10933950 DOI: 10.1006/Mthe.2000.0045  0.476
2000 Chirmule N, Xiao W, Truneh A, Schnell MA, Hughes JV, Zoltick P, Wilson JM. Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle. Journal of Virology. 74: 2420-5. PMID 10666273 DOI: 10.1128/Jvi.74.5.2420-2425.2000  0.489
2000 Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-Alanine Mutagenesis of the Adeno-Associated Virus Type 2 Rep78/68 Proteins Yields Temperature-Sensitive and Magnesium-Dependent Variants Journal of Virology. 74: 591-591. DOI: 10.1128/Jvi.74.1.591-591.2000  0.582
1999 Rabinowitz JE, Xiao W, Samulski RJ. Insertional mutagenesis of AAV2 capsid and the production of recombinant virus Virology. 265: 274-285. PMID 10600599 DOI: 10.1006/Viro.1999.0045  0.398
1999 Bals R, Xiao W, Sang N, Weiner DJ, Meegalla RL, Wilson JM. Transduction of well-differentiated airway epithelium by recombinant adeno-associated virus is limited by vector entry. Journal of Virology. 73: 6085-8. PMID 10364362 DOI: 10.1128/Jvi.73.7.6085-6088.1999  0.421
1999 Xiao W, Chirmule N, Berta SC, McCullough B, Gao G, Wilson JM. Gene therapy vectors based on adeno-associated virus type 1. Journal of Virology. 73: 3994-4003. PMID 10196295 DOI: 10.1128/Jvi.73.5.3994-4003.1999  0.524
1999 Ye X, Sachar J, Lisska E, Xiao W, Robinson MB, Wilson JM, Batshaw ML. Adeno-Associated Virus(AAV)-Mediated Expression of Ornithine Transcarbamylase (OTC) in OTC Deficient spf-ash mMice Pediatric Research. 45: 142A-142A. DOI: 10.1203/00006450-199904020-00845  0.479
1998 Gao GP, Qu G, Faust LZ, Engdahl RK, Xiao W, Hughes JV, Zoltick PW, Wilson JM. High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus. Human Gene Therapy. 9: 2353-62. PMID 9829534 DOI: 10.1089/Hum.1998.9.16-2353  0.538
1998 Xiao W, Berta SC, Lu MM, Moscioni AD, Tazelaar J, Wilson JM. Adeno-associated virus as a vector for liver-directed gene therapy. Journal of Virology. 72: 10222-6. PMID 9811765 DOI: 10.1128/Jvi.72.12.10222-10226.1998  0.503
Show low-probability matches.