Michael A. Lynes - Publications

Affiliations: 
University of Connecticut at Storrs 
Area:
immunotoxicology, metallothionein, chronic inflammation, high content microarray biotechnology, chemotaxis

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Dostie KE, Thees AV, Lynes MA. Metallothionein: a Novel Therapeutic Target for Treatment of Inflammatory Bowel Disease. Current Pharmaceutical Design. PMID 30014800 DOI: 10.2174/1381612824666180717110236  0.326
2017 Bhandari S, Melchiorre C, Dostie K, Laukens D, Devisscher L, Louwrier A, Thees A, Lynes MA. Detection and Manipulation of the Stress Response Protein Metallothionein. Current Protocols in Toxicology. 71: 17.19.1-17.19.28. PMID 28146278 DOI: 10.1002/Cptx.17  0.324
2016 Rice JM, Zweifach A, Lynes MA. Metallothionein regulates intracellular zinc signaling during CD4(+) T cell activation. Bmc Immunology. 17: 13. PMID 27251638 DOI: 10.1186/S12865-016-0151-2  0.305
2015 Emeny RT, Kasten-Jolly J, Mondal T, Lynes MA, Lawrence DA. Metallothionein differentially affects the host response to Listeria infection both with and without an additional stress from cold-restraint. Cell Stress & Chaperones. 20: 1013-22. PMID 26267326 DOI: 10.1007/S12192-015-0630-Z  0.363
2014 Lynes MA, Hidalgo J, Manso Y, Devisscher L, Laukens D, Lawrence DA. Metallothionein and stress combine to affect multiple organ systems. Cell Stress & Chaperones. 19: 605-11. PMID 24584987 DOI: 10.1007/S12192-014-0501-Z  0.301
2014 Devisscher L, Hindryckx P, Lynes MA, Waeytens A, Cuvelier C, De Vos F, Vanhove C, Vos MD, Laukens D. Role of metallothioneins as danger signals in the pathogenesis of colitis. The Journal of Pathology. 233: 89-100. PMID 24452846 DOI: 10.1002/Path.4330  0.4
2013 Pietrosimone KM, Bhandari S, Lemieux MG, Knecht DA, Lynes MA. In vitro assays of chemotaxis as a window into mechanisms of toxicant-induced immunomodulation. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 58: Unit 18.17.. PMID 24510542 DOI: 10.1002/0471140856.Tx1817S58  0.304
2013 Wanczyk H, Barker T, Rood D, Zapata DI, Howell AR, Richardson SK, Zinckgraf J, Marusov GP, Lynes MA, Silbart LK. Cloning and characterization of a hybridoma secreting a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-specific monoclonal antibody and recombinant F(ab). Toxins. 5: 568-89. PMID 23518474 DOI: 10.3390/Toxins5030568  0.335
2013 Devisscher L, Hindryckx P, Olievier K, Peeters H, Lynes M, Cuvelier CA, De Vos M, Laukens D. Sa1846 Metallothionein, an Emerging Danger Signal During Experimental Colitis Gastroenterology. 144: S-319. DOI: 10.1016/S0016-5085(13)61156-7  0.366
2012 Pietrosimone KM, Yin X, Knecht DA, Lynes MA. Measurement of cellular chemotaxis with ECIS/Taxis. Journal of Visualized Experiments : Jove. PMID 22491349 DOI: 10.3791/3840  0.32
2012 Rice JM, Stern LJ, Guignon EF, Lawrence DA, Lynes MA. Antigen-specific T cell phenotyping microarrays using grating coupled surface plasmon resonance imaging and surface plasmon coupled emission. Biosensors & Bioelectronics. 31: 264-9. PMID 22104646 DOI: 10.1016/J.Bios.2011.10.029  0.364
2012 Marusov G, Sweatt A, Pietrosimone K, Benson D, Geary SJ, Silbart LK, Challa S, Lagoy J, Lawrence DA, Lynes MA. A microarray biosensor for multiplexed detection of microbes using grating-coupled surface plasmon resonance imaging. Environmental Science & Technology. 46: 348-59. PMID 22029256 DOI: 10.1021/Es201239F  0.31
2010 Lynes MA. Immunochemical Analysis of the Temporal and Tissue-Specific Expression of an Avena sativa Plasma Membrane Determinant. Plant Physiology. 98: 24-33. PMID 16668621 DOI: 10.1104/Pp.98.1.24  0.318
2009 Emeny RT, Marusov G, Lawrence DA, Pederson-Lane J, Yin X, Lynes MA. Manipulations of metallothionein gene dose accelerate the response to Listeria monocytogenes. Chemico-Biological Interactions. 181: 243-53. PMID 19576872 DOI: 10.1016/J.Cbi.2009.06.018  0.385
2009 Lynes MA. Molecular and Cellular Concepts in Toxicology General, Applied and Systems Toxicology. DOI: 10.1002/9780470744307.Gat012  0.312
2007 Hadjout N, Yin X, Knecht DA, Lynes MA. Automated real-time measurements of leukocyte chemotaxis. Journal of Immunological Methods. 320: 70-80. PMID 17275834 DOI: 10.1016/J.Jim.2006.12.005  0.313
2006 Lynes MA, Zaffuto K, Unfricht DW, Marusov G, Samson JS, Yin X. The physiological roles of extracellular metallothionein. Experimental Biology and Medicine (Maywood, N.J.). 231: 1548-54. PMID 17018879 DOI: 10.1177/153537020623100915  0.331
2006 Jin GB, Unfricht DW, Fernandez SM, Lynes MA. Cytometry on a chip: cellular phenotypic and functional analysis using grating-coupled surface plasmon resonance. Biosensors & Bioelectronics. 22: 200-6. PMID 16455238 DOI: 10.1016/J.Bios.2005.12.021  0.335
2005 Lynes MA. Solid-phase immunoassays. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit18.7. PMID 23045119 DOI: 10.1002/0471140856.Tx1807S23  0.341
2005 Unfricht DW, Colpitts SL, Fernandez SM, Lynes MA. Grating-coupled surface plasmon resonance: a cell and protein microarray platform. Proteomics. 5: 4432-42. PMID 16222719 DOI: 10.1002/Pmic.200401314  0.336
2005 Yin X, Knecht DA, Lynes MA. Metallothionein mediates leukocyte chemotaxis. Bmc Immunology. 6: 21. PMID 16164753 DOI: 10.1186/1471-2172-6-21  0.305
2003 Lyons BL, Lynes MA, Burzenski L, Joliat MJ, Hadjout N, Shultz LD. Mechanisms of anemia in SHP-1 protein tyrosine phosphatase-deficient "viable motheaten" mice. Experimental Hematology. 31: 234-43. PMID 12644021 DOI: 10.1016/S0301-472X(02)01031-7  0.331
2002 Youn J, Hwang SH, Ryoo ZY, Lynes MA, Paik DJ, Chung HS, Kim HY. Metallothionein suppresses collagen-induced arthritis via induction of TGF-beta and down-regulation of proinflammatory mediators. Clinical and Experimental Immunology. 129: 232-9. PMID 12165078 DOI: 10.1046/J.1365-2249.2002.01922.X  0.332
2002 Joliat MJ, Lang PA, Lyons BL, Burzenski L, Lynes MA, Yi T, Sundberg JP, Shultz LD. Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice. Journal of Autoimmunity. 18: 105-17. PMID 11908943 DOI: 10.1006/Jaut.2001.0570  0.345
2001 Hadjout N, Laevsky G, Knecht DA, Lynes MA. Automated real-time measurement of chemotactic cell motility. Biotechniques. 31: 1130-8. PMID 11730019 DOI: 10.2144/01315Rr02  0.335
2001 Brooks WP, Lynes MA. Effects of hemizygous CD45 expression in the autoimmune Fasl(gld/gld) syndrome. Cellular Immunology. 212: 24-34. PMID 11716526 DOI: 10.1006/Cimm.2001.1845  0.32
2001 Canpolat E, Lynes MA. In vivo manipulation of endogenous metallothionein with a monoclonal antibody enhances a T-dependent humoral immune response. Toxicological Sciences : An Official Journal of the Society of Toxicology. 62: 61-70. PMID 11399794 DOI: 10.1093/Toxsci/62.1.61  0.417
2000 Crowthers KC, Kline V, Giardina C, Lynes MA. Augmented humoral immune function in metallothionein-null mice. Toxicology and Applied Pharmacology. 166: 161-72. PMID 10906280 DOI: 10.1006/Taap.2000.8961  0.399
1999 Youn J, Lynes MA. Metallothionein-induced suppression of cytotoxic T lymphocyte function: An important immunoregulatory control Toxicological Sciences. 52: 199-208. PMID 10630572 DOI: 10.1093/Toxsci/52.2.199  0.4
1996 Ling W, Tibbetts DJ, Crain RC, Lynes MA. The phosphotyrosine phosphatase inhibitor-phenylarsine oxide restores defective phosphoinositide hydrolysis response in anergic C3H-gld/gld lymphocytes Immunology and Cell Biology. 74: 231-238. PMID 8799722 DOI: 10.1038/Icb.1996.42  0.346
1996 Borghesi LA, Lynes MA. Nonprotective effects of extracellular metallothionein. Toxicology and Applied Pharmacology. 139: 6-14. PMID 8685909 DOI: 10.1006/Taap.1996.0137  0.403
1996 Borghesi LA, Youn J, Olson EA, Lynes MA. Interactions of metallothionein with murine lymphocytes: plasma membrane binding and proliferation. Toxicology. 108: 129-40. PMID 8644111 DOI: 10.1016/S0300-483X(95)03243-9  0.42
1995 Youn J, Borghesi LA, Olson EA, Lynes MA. Immunomodulatory activities of extracellular metallothionein. II. Effects on macrophage functions. Journal of Toxicology and Environmental Health. 45: 397-413. PMID 7643428 DOI: 10.1080/15287399509532004  0.355
1993 Lynes MA, Borghesi LA, Youn J, Olson EA. Immunomodulatory activities of extracellular metallothionein. I. Metallothionein effects on antibody production. Toxicology. 85: 161-77. PMID 8303711 DOI: 10.1016/0300-483X(93)90040-Y  0.329
1987 Lynes M, Lamb CA, Napolitano LA, Stout RG. Antibodies to cell-surface antigens of plant protoplasts Plant Science. 50: 225-232. DOI: 10.1016/0168-9452(87)90077-X  0.349
1984 Lynes MA, Flaherty L, Michaelson J, Collins JJ, Rinchik EM. Allogeneic reactivity in normal mouse serum. Journal of Immunogenetics. 11: 189-96. PMID 6520407 DOI: 10.1111/J.1744-313X.1984.Tb01056.X  0.407
1984 Flaherty L, Lynes MA. Use of monoclonal antibodies in the study of the fine specificity of antigens coded for by the major histocompatibility complex in mice. Methods in Enzymology. 108: 481-94. PMID 6084800 DOI: 10.1016/S0076-6879(84)08113-1  0.337
1982 Lanier LL, Arnold LW, Raybourne RB, Russell S, Lynes MA, Warner NL, Haughton G. Transplantable B-cell lymphomas in B10. H-2aH-4bp/Wts mice. Immunogenetics. 16: 367-71. PMID 6983495 DOI: 10.1007/Bf00372309  0.598
1982 Rudofsky UH, Dilwith RL, Lynes M, Flaherty L. Murine monoclonal antikidney autoantibodies. I. Anti-renal proximal tubular basement membrane autoantibodies. Clinical Immunology and Immunopathology. 25: 165-78. PMID 6187505 DOI: 10.1016/0090-1229(82)90179-9  0.363
1982 Lynes MA, Karl M, DiBiase K, Flaherty L. Supramolecular relationships of membrane antigens on the murine thymocyte. Journal of Immunogenetics. 9: 475-84. PMID 6131095 DOI: 10.1111/J.1744-313X.1982.Tb01009.X  0.354
1981 Wiener F, Babonits M, Spira J, Bregula U, Klein G, Merwin RM, Asofsky R, Lynes M, Haughton G. Chromosome 15 trisomy in spontaneous and carcinogen-induced murine lymphomas of B-cell origin. International Journal of Cancer. 27: 51-8. PMID 6788720 DOI: 10.1002/Ijc.2910270109  0.601
1979 Lanier LL, Babcock GF, Lynes MA, Haughton G. Antigen-induced murine B-cell lymphomas. III. Passive anti-idiotype serum therapy and its combined effect with chemotherapy. Journal of the National Cancer Institute. 63: 1417-22. PMID 316036  0.611
1979 Lanier LL, Babcock GF, Lynes MA, Haughton G. Early detection of the CH1 murine lymphoma by tumor-associated idiotype in the serum. International Journal of Cancer. 24: 53-9. PMID 314422 DOI: 10.1002/Ijc.2910240110  0.587
1979 Lanier LL, Babcock GF, Lynes MA, Haughton G. Antigen-Induced Murine B-Cell Lymphomas. III. Passive Anti-idiotype Serum Therapy and Its Combined Effect With Chemotherapy Journal of the National Cancer Institute. 63: 1417-1422. DOI: 10.1093/Jnci/63.6.1417  0.633
1978 Lanier LL, Lynes M, Haughton G, Wettstein PJ. Novel type of murine B-cell lymphoma. Nature. 271: 554-5. PMID 304532 DOI: 10.1038/271554A0  0.631
1978 Babcock GF, Lanier LL, Lynes MA, Haughton G. A simple method for the preparation of antisera specific for murine immunoglobulin heavy chains. Journal of Immunological Methods. 23: 1-6. PMID 100558 DOI: 10.1016/0022-1759(78)90103-5  0.617
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