| Year |
Citation |
Score |
| 2022 |
Kuzuoglu-Ozturk D, Aksoy O, Schmidt C, Lea R, Larson JD, Phelps RRL, Nasholm N, Holt M, Contreras A, Huang M, Wong-Michalak S, Shao H, Wechsler-Reya R, Phillips JJ, Gestwicki JE, ... Ruggero D, et al. N-myc mediated translation control is a therapeutic vulnerability in medulloblastoma. Cancer Research. PMID 36264168 DOI: 10.1158/0008-5472.CAN-22-0945 |
0.339 |
|
| 2022 |
Barna M, Karbstein K, Tollervey D, Ruggero D, Brar G, Greer EL, Dinman JD. The promises and pitfalls of specialized ribosomes. Molecular Cell. 82: 2179-2184. PMID 35714581 DOI: 10.1016/j.molcel.2022.05.035 |
0.493 |
|
| 2022 |
Kovalski JR, Kuzuoglu-Ozturk D, Ruggero D. Protein synthesis control in cancer: selectivity and therapeutic targeting. The Embo Journal. e109823. PMID 35315941 DOI: 10.15252/embj.2021109823 |
0.378 |
|
| 2021 |
Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D. ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance. Cell. PMID 34559986 DOI: 10.1016/j.cell.2021.08.036 |
0.302 |
|
| 2021 |
Chiu H, Buono R, Jackson LV, Herzog LO, Mallya S, Conn CS, Ruggero D, Fruman DA. Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function. Iscience. 24: 102748. PMID 34278258 DOI: 10.1016/j.isci.2021.102748 |
0.721 |
|
| 2021 |
Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D. Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Reports. 35: 109321. PMID 34192540 DOI: 10.1016/j.celrep.2021.109321 |
0.343 |
|
| 2021 |
Kovalski JR, Xu Y, Ruggero D. Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer. Methods in Molecular Biology (Clifton, N.J.). 2318: 255-266. PMID 34019295 DOI: 10.1007/978-1-0716-1476-1_13 |
0.328 |
|
| 2021 |
Conn CS, Yang H, Tom HJ, Ikeda K, Oses-Prieto JA, Vu H, Oguri Y, Nair S, Gill RM, Kajimura S, DeBerardinis RJ, Burlingame AL, Ruggero D. The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. Nature Metabolism. 3: 244-257. PMID 33619378 DOI: 10.1038/s42255-021-00349-z |
0.709 |
|
| 2020 |
Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, ... ... Ruggero D, et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. PMID 32353859 DOI: 10.1038/S41586-020-2286-9 |
0.327 |
|
| 2020 |
Xu Y, Ruggero D. The Role of Translation Control in Tumorigenesis and Its Therapeutic Implications Annual Review of Cancer Biology. 4: 437-457. DOI: 10.1146/annurev-cancerbio-030419-033420 |
0.367 |
|
| 2019 |
Wei J, Leung K, Truillet C, Ruggero D, Wells J, Evans MJ. Profiling the surfaceome identifies therapeutic targets for cells with hyperactive mTORC1 signaling. Molecular & Cellular Proteomics : McP. PMID 31792071 DOI: 10.1074/Mcp.Ra119.001785 |
0.395 |
|
| 2019 |
McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, ... Ruggero D, et al. A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. Elife. 8. PMID 31478838 DOI: 10.7554/Elife.48847 |
0.367 |
|
| 2019 |
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salinas CS, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, ... ... Ruggero D, et al. Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature Cell Biology. PMID 31316187 DOI: 10.1038/S41556-019-0370-X |
0.717 |
|
| 2019 |
Fish L, Navickas A, Culbertson B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Alarcón C, Ruggero D, Goodarzi H. Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Molecular Cell. PMID 31300274 DOI: 10.1016/J.Molcel.2019.06.001 |
0.388 |
|
| 2019 |
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, ... ... Ruggero D, et al. ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature Cell Biology. 21: 889-899. PMID 31263264 DOI: 10.1038/S41556-019-0347-9 |
0.77 |
|
| 2019 |
Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S. A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis. Cell Host & Microbe. PMID 30827827 DOI: 10.1016/J.Chom.2019.01.006 |
0.379 |
|
| 2019 |
Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, ... ... Ruggero D, et al. Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nature Medicine. PMID 30643286 DOI: 10.1038/S41591-018-0321-2 |
0.4 |
|
| 2019 |
Forester CM, Woo-Byeon G, Oses-Prieto J, Burlingame A, Barna M, Ruggero DM. Regulation of eIF4E Guides a Unique Translational Program to Steer Erythroid Maturation Blood. 134: 156-156. DOI: 10.1182/Blood-2019-129608 |
0.338 |
|
| 2018 |
Chiu H, Jackson LV, Oh KI, Mai A, Ronai ZA, Ruggero D, Fruman DA. The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 30530594 DOI: 10.4049/Jimmunol.1800602 |
0.401 |
|
| 2018 |
McMahon M, Ruggero D. A Translation Tuning HuDdle for Neurons. Molecular Cell. 71: 195-196. PMID 30028999 DOI: 10.1016/J.Molcel.2018.07.007 |
0.348 |
|
| 2018 |
McMahon M, Ruggero D. A wobbly road to drug resistance in melanoma: tRNA-modifying enzymes in translation reprogramming. The Embo Journal. PMID 29967029 DOI: 10.15252/Embj.201899978 |
0.345 |
|
| 2018 |
Robichaud N, Sonenberg N, Ruggero D, Schneider RJ. Translational Control in Cancer. Cold Spring Harbor Perspectives in Biology. PMID 29959193 DOI: 10.1101/Cshperspect.A032896 |
0.456 |
|
| 2018 |
Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, ... ... Ruggero D, et al. Development of a stress response therapy targeting aggressive prostate cancer. Science Translational Medicine. 10. PMID 29720449 DOI: 10.1126/Scitranslmed.Aar2036 |
0.769 |
|
| 2018 |
Forester CM, Zhao Q, Phillips NJ, Urisman A, Chalkley RJ, Oses-Prieto JA, Zhang L, Ruggero D, Burlingame AL. Revealing nascent proteomics in signaling pathways and cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29467287 DOI: 10.1073/Pnas.1707514115 |
0.38 |
|
| 2018 |
Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, Conn CS, Simpson DR, Scott AI, Le A, Cowan TM, Ruggero D, Sweet-Cordero EA. Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase. Cancer Cell. 33: 91-107.e6. PMID 29316436 DOI: 10.1016/J.Ccell.2017.12.003 |
0.758 |
|
| 2018 |
Evans MJ, Truillet C, Ruggero D, Lewis JS, Aggarwal R, Behr SC. Abstract 3694: Measuring oncogene signaling with transferrin-based PET: From bench to bedside Cancer Research. 78: 3694-3694. DOI: 10.1158/1538-7445.Am2018-3694 |
0.369 |
|
| 2017 |
Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nature Cell Biology. PMID 29230015 DOI: 10.1038/S41556-017-0006-Y |
0.395 |
|
| 2017 |
Ruggero D, Shaw RJ. Editorial overview: Cell regulation: 1000 Flavors including chocolate and chili peppers. Current Opinion in Cell Biology. 45: iv-vi. PMID 28641761 DOI: 10.1016/J.Ceb.2017.05.008 |
0.347 |
|
| 2017 |
Truitt ML, Ruggero D. New frontiers in translational control of the cancer genome. Nature Reviews. Cancer. 17: 332. PMID 28436470 DOI: 10.1038/Nrc.2017.30 |
0.428 |
|
| 2017 |
Silva JM, Bagni RK, Ruggero D, McCormick F. Abstract B11: Oncogenic KRAS regulates 4E-BP1, a repressor of cap-dependent translation, independently of growth factor activity Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-B11 |
0.36 |
|
| 2017 |
Conn CS, Nguyen HG, Kye Y, Cunningham JT, Truillet C, Evans M, Huynh TL, Walters P, Ruggero D. Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-A25 |
0.778 |
|
| 2016 |
Truillet C, Cunningham JT, Parker MF, Huynh LT, Conn CS, Ruggero D, Lewis JS, Evans MJ. Non-invasive measurement of mTORC1 signaling with 89Zr-transferrin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28007777 DOI: 10.1158/1078-0432.Ccr-16-2448 |
0.73 |
|
| 2016 |
So L, Lee J, Palafox M, Mallya S, Woxland CG, Arguello M, Truitt ML, Sonenberg N, Ruggero D, Fruman DA. The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes. Science Signaling. 9: ra57. PMID 27245614 DOI: 10.1126/Scisignal.Aad8463 |
0.358 |
|
| 2015 |
Hsieh AC, Nguyen HG, Wen L, Edlind MP, Carroll PR, Kim W, Ruggero D. Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors. Science Signaling. 8: ra116. PMID 26577921 DOI: 10.1126/Scisignal.Aad5111 |
0.41 |
|
| 2015 |
Truitt ML, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady AM, Seo Y, Barna M, Ruggero D. Differential Requirements for eIF4E Dose in Normal Development and Cancer. Cell. 162: 59-71. PMID 26095252 DOI: 10.1016/J.Cell.2015.05.049 |
0.756 |
|
| 2015 |
Fujita-Sato S, Galeas J, Truitt M, Pitt C, Urisman A, Bandyopadhyay S, Ruggero D, McCormick F. Enhanced MET Translation and Signaling Sustains K-Ras-Driven Proliferation under Anchorage-Independent Growth Conditions. Cancer Research. 75: 2851-62. PMID 25977330 DOI: 10.1158/0008-5472.Can-14-1623 |
0.303 |
|
| 2015 |
Sheridan CM, Grogan TR, Nguyen HG, Galet C, Rettig MB, Hsieh AC, Ruggero D. YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence. Oncotarget. 6: 7470-80. PMID 25797255 DOI: 10.18632/Oncotarget.3477 |
0.395 |
|
| 2015 |
Pelletier J, Graff J, Ruggero D, Sonenberg N. Targeting the eIF4F translation initiation complex: a critical nexus for cancer development. Cancer Research. 75: 250-63. PMID 25593033 DOI: 10.1158/0008-5472.Can-14-2789 |
0.49 |
|
| 2015 |
McMahon M, Contreras A, Ruggero D. Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease. Wiley Interdisciplinary Reviews. Rna. 6: 173-89. PMID 25363811 DOI: 10.1002/Wrna.1266 |
0.331 |
|
| 2015 |
Forester CM, Shi Z, Barna M, Ruggero D. A Tailor-Made Protein Synthesis Program Drives Erythroid Development and Disease Blood. 126: 3581-3581. DOI: 10.1182/Blood.V126.23.3581.3581 |
0.435 |
|
| 2015 |
Stumpf C, Cunningham T, Ruggero D. Abstract PR07: Myc-dependent translation makes an impact: Tailor-made protein expression for cancer development Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-Pr07 |
0.486 |
|
| 2014 |
Ruggero D, Shimamura A. Marrow failure: a window into ribosome biology. Blood. 124: 2784-92. PMID 25237201 DOI: 10.1182/Blood-2014-04-526301 |
0.325 |
|
| 2014 |
Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D. Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cell. 157: 1088-103. PMID 24855946 DOI: 10.1016/J.Cell.2014.03.052 |
0.464 |
|
| 2014 |
Barna M, Ruggero D. Tailor made protein synthesis for HSCs Cell Stem Cell. 14: 423-424. PMID 24702992 DOI: 10.1016/J.Stem.2014.03.011 |
0.363 |
|
| 2014 |
Han K, Jaimovich A, Dey G, Ruggero D, Meyuhas O, Sonenberg N, Meyer T. Parallel measurement of dynamic changes in translation rates in single cells. Nature Methods. 11: 86-93. PMID 24213167 DOI: 10.1038/Nmeth.2729 |
0.404 |
|
| 2014 |
Lucena-Araujo AR, Santana-Lemos BA, Thome CH, Ferreira GA, Ruggero D, Faça VM, Rego EM. Early Hematopoietic Progenitors of Dkc1 Hypomorphic Mutant Mice Display Decreased Proliferation Rate and an Impaired Control of Serine/Arginine-Rich Splicing Factor 4 (Srsf4) Translation Blood. 124: 2937-2937. DOI: 10.1182/Blood.V124.21.2937.2937 |
0.389 |
|
| 2014 |
Meyerowitz JG, Gustafson WC, Nekritz E, Swartling F, Shokat KM, Ruggero D, Weiss WA. Abstract B78: Targeting the translational apparatus in MYCN-driven medulloblastoma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-B78 |
0.41 |
|
| 2014 |
Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D. Erratum: Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer (Cell (2014) 157 (1088-1103)) Cell. 158. DOI: 10.1016/J.Cell.2014.07.008 |
0.345 |
|
| 2013 |
Cunningham JT, Ruggero D. New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization. Cancer Discovery. 3: 1099-102. PMID 24124229 DOI: 10.1158/2159-8290.Cd-13-0581 |
0.432 |
|
| 2013 |
Stumpf CR, Moreno MV, Olshen AB, Taylor BS, Ruggero D. The translational landscape of the mammalian cell cycle. Molecular Cell. 52: 574-82. PMID 24120665 DOI: 10.1016/J.Molcel.2013.09.018 |
0.393 |
|
| 2013 |
Olshen AB, Hsieh AC, Stumpf CR, Olshen RA, Ruggero D, Taylor BS. Assessing gene-level translational control from ribosome profiling. Bioinformatics (Oxford, England). 29: 2995-3002. PMID 24048356 DOI: 10.1093/Bioinformatics/Btt533 |
0.39 |
|
| 2013 |
Cunningham JT, Pourdehnad M, Stumpf CR, Ruggero D. Investigating Myc-dependent translational regulation in normal and cancer cells. Methods in Molecular Biology (Clifton, N.J.). 1012: 201-12. PMID 24006066 DOI: 10.1007/978-1-62703-429-6_13 |
0.435 |
|
| 2013 |
Pourdehnad M, Truitt ML, Siddiqi IN, Ducker GS, Shokat KM, Ruggero D. Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers. Proceedings of the National Academy of Sciences of the United States of America. 110: 11988-93. PMID 23803853 DOI: 10.1073/Pnas.1310230110 |
0.505 |
|
| 2013 |
Santini E, Huynh TN, MacAskill AF, Carter AG, Pierre P, Ruggero D, Kaphzan H, Klann E. Exaggerated translation causes synaptic and behavioural aberrations associated with autism. Nature. 493: 411-5. PMID 23263185 DOI: 10.1038/Nature11782 |
0.303 |
|
| 2013 |
Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, et al. Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature. 493: 371-7. PMID 23172145 DOI: 10.1038/Nature11628 |
0.366 |
|
| 2013 |
Ruggero D. Translational control in cancer etiology. Cold Spring Harbor Perspectives in Biology. 5. PMID 22767671 DOI: 10.1101/Cshperspect.A012336 |
0.453 |
|
| 2013 |
Ruggero D. Abstract IA8: Novel insights into synthetic lethal interactions in cancer: Common nodes in protein synthesis control and nucleotide metabolism Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia8 |
0.504 |
|
| 2013 |
Stumpf CR, Moreno MV, Olshen AB, Taylor BS, Ruggero D. Abstract A57: Plasticity of the translational landscape during the mammalian cell cycle: Implications and new insights for cancer cell proliferation Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A57 |
0.448 |
|
| 2013 |
Pourdehnad M, Truitt ML, Siddiqi IN, Ducker GS, Shokat KM, Ruggero D. Abstract A46: Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A46 |
0.505 |
|
| 2013 |
Koumenis C, Hart LS, Cunningham T, Dey S, Tameire F, Mills I, Ruggero D, Diehl AJ, Fuchs S. Abstract SY32-04: The translation initiation factor elF2α regulates cytoprotective autophagy in Myc-dependent lymphoma. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy32-04 |
0.506 |
|
| 2012 |
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, ... ... Ruggero D, et al. ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. The Journal of Clinical Investigation. 122: 4621-34. PMID 23143306 DOI: 10.1172/Jci62973 |
0.431 |
|
| 2012 |
Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA. IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science (New York, N.Y.). 338: 818-22. PMID 23042294 DOI: 10.1126/Science.1226191 |
0.398 |
|
| 2012 |
Ruggero D. Revisiting the nucleolus: from marker to dynamic integrator of cancer signaling. Science Signaling. 5: pe38. PMID 22969157 DOI: 10.1126/Scisignal.2003477 |
0.44 |
|
| 2012 |
Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, ... ... Ruggero D, et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 485: 55-61. PMID 22367541 DOI: 10.1038/Nature10912 |
0.448 |
|
| 2012 |
McCauley JA, Evenson K, Truitt M, Kratzke R, Polunovsky V, Ruggero D, BItterman P, D'Cunha J. Abstract 2347: Translational control and lung cancer: eIF4F activation promotes tumorigenesis in vivo Cancer Research. 72: 2347-2347. DOI: 10.1158/1538-7445.Am2012-2347 |
0.435 |
|
| 2011 |
Jack K, Bellodi C, Landry DM, Niederer RO, Meskauskas A, Musalgaonkar S, Kopmar N, Krasnykh O, Dean AM, Thompson SR, Ruggero D, Dinman JD. rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells. Molecular Cell. 44: 660-6. PMID 22099312 DOI: 10.1016/J.Molcel.2011.09.017 |
0.597 |
|
| 2011 |
Hsieh AC, Truitt ML, Ruggero D. Oncogenic AKTivation of translation as a therapeutic target. British Journal of Cancer. 105: 329-36. PMID 21772331 DOI: 10.1038/Bjc.2011.241 |
0.479 |
|
| 2011 |
Stumpf CR, Ruggero D. The cancerous translation apparatus. Current Opinion in Genetics & Development. 21: 474-83. PMID 21543223 DOI: 10.1016/J.Gde.2011.03.007 |
0.469 |
|
| 2011 |
Koumenis C, Zhang H, Bi M, Lehman SL, Datta T, Liu H, Thomas-Tikhonenko A, Koong A, Fuchs SY, Diehl JA, Ruggero D. Abstract SY06-02: Activation of the UPR by c-Myc promotes transformation and tumorigenesis via cytoprotective autophagy Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy06-02 |
0.465 |
|
| 2011 |
Hart LS, Cunningham T, Datta T, Liu H, Koong AC, Fuchs S, Diehl JA, Ruggero D, Koumenis C. Abstract 2078: PERK-mediated autophagy promotes Myc-induced transformation and tumorigenesis Cancer Research. 71: 2078-2078. DOI: 10.1158/1538-7445.Am2011-2078 |
0.462 |
|
| 2010 |
Hsieh AC, Ruggero D. Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4914-20. PMID 20702611 DOI: 10.1158/1078-0432.Ccr-10-0433 |
0.416 |
|
| 2010 |
Bellodi C, Krasnykh O, Haynes N, Theodoropoulou M, Peng G, Montanaro L, Ruggero D. Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis Cancer Research. 70: 6026-6035. PMID 20587522 DOI: 10.1158/0008-5472.Can-09-4730 |
0.386 |
|
| 2010 |
Bellodi C, Kopmar N, Ruggero D. Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita. The Embo Journal. 29: 1865-76. PMID 20453831 DOI: 10.1038/Emboj.2010.83 |
0.382 |
|
| 2010 |
Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, Meyuhas O, Shokat KM, Ruggero D. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell. 17: 249-61. PMID 20227039 DOI: 10.1016/J.Ccr.2010.01.021 |
0.464 |
|
| 2009 |
Ruggero D. The role of Myc-induced protein synthesis in cancer. Cancer Research. 69: 8839-43. PMID 19934336 DOI: 10.1158/0008-5472.Can-09-1970 |
0.488 |
|
| 2009 |
Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. Plos Biology. 7: e38. PMID 19209957 DOI: 10.1371/Journal.Pbio.1000038 |
0.409 |
|
| 2008 |
Barna M, Pusic A, Zollo O, Costa M, Kondrashov N, Rego E, Rao PH, Ruggero D. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency Nature. 456: 971-975. PMID 19011615 DOI: 10.1038/Nature07449 |
0.495 |
|
| 2007 |
Ruggero D, Yoon A, Peng G, Zollo O, Adamo R, Haynes N, Xu W, Rego E. 130 INVITED Novel insight into the pathogenesis of dyskeratosis congenita: how defective ribosome activity can cause cancer and disease Ejc Supplements. 5: 35-36. DOI: 10.1016/S1359-6349(07)70244-6 |
0.348 |
|
| 2006 |
Yoon A, Peng G, Brandenburger Y, Brandenburg Y, Zollo O, Xu W, Rego E, Ruggero D. Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita. Science (New York, N.Y.). 312: 902-6. PMID 16690864 DOI: 10.1126/Science.1123835 |
0.382 |
|
| 2006 |
Rego EM, Ruggero D, Tribioli C, Cattoretti G, Kogan S, Redner RL, Pandolfi PP. Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha. Oncogene. 25: 1974-9. PMID 16331271 DOI: 10.1038/Sj.Onc.1209216 |
0.429 |
|
| 2005 |
Ruggero D, Sonenberg N. The Akt of translational control. Oncogene. 24: 7426-34. PMID 16288289 DOI: 10.1038/Sj.Onc.1209098 |
0.511 |
|
| 2004 |
Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C, Pandolfi PP. The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nature Medicine. 10: 484-6. PMID 15098029 DOI: 10.1038/Nm1042 |
0.569 |
|
| 2003 |
Ruggero D, Pandolfi PP. Does the ribosome translate cancer? Nature Reviews. Cancer. 3: 179-92. PMID 12612653 DOI: 10.1038/Nrc1015 |
0.617 |
|
| 2003 |
Ruggero D, Grisendi S, Piazza F, Rego E, Mari F, Rao PH, Cordon-Cardo C, Pandolfi PP. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science (New York, N.Y.). 299: 259-62. PMID 12522253 DOI: 10.1126/Science.1079447 |
0.479 |
|
| 2002 |
Barna M, Merghoub T, Costoya JA, Ruggero D, Branford M, Bergia A, Samori B, Pandolfi PP. Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. Developmental Cell. 3: 499-510. PMID 12408802 DOI: 10.1016/S1534-5807(02)00289-7 |
0.474 |
|
| 2000 |
Ruggero D, Wang ZG, Pandolfi PP. The puzzling multiple lives of PML and its role in the genesis of cancer. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 827-35. PMID 10944585 DOI: 10.1002/1521-1878(200009)22:9<827::Aid-Bies8>3.0.Co;2-1 |
0.563 |
|
| 2000 |
Zhong S, Salomoni P, Ronchetti S, Guo A, Ruggero D, Pandolfi PP. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. The Journal of Experimental Medicine. 191: 631-40. PMID 10684855 DOI: 10.1084/Jem.191.4.631 |
0.545 |
|
| 1999 |
Condò I, Ciammaruconi A, Benelli D, Ruggero D, Londei P. Cis‐acting signals controlling translational initiation in the thermophilic archaeon Sulfolobus solfataricus Molecular Microbiology. 34: 377-384. PMID 10564480 DOI: 10.1046/J.1365-2958.1999.01615.X |
0.338 |
|
| 1998 |
Wang ZG, Ruggero D, Ronchetti S, Zhong S, Gaboli M, Rivi R, Pandolfi PP. PML is essential for multiple apoptotic pathways. Nature Genetics. 20: 266-72. PMID 9806545 DOI: 10.1038/3073 |
0.488 |
|
| 1998 |
Condò I, Ruggero D, Reinhardt R, Londei P. A novel aminopeptidase associated with the 60 kDa chaperonin in the thermophilic archaeon Sulfolobus solfataricus Molecular Microbiology. 29: 775-785. PMID 9723917 DOI: 10.1046/J.1365-2958.1998.00971.X |
0.318 |
|
| 1998 |
Ruggero D, Ciammaruconi A, Londei P. The chaperonin of the archaeon Sulfolobus solfataricus is an RNA-binding protein that participates in ribosomal RNA processing The Embo Journal. 17: 3471-3477. PMID 9628882 DOI: 10.1093/Emboj/17.12.3471 |
0.32 |
|
| 1993 |
Ruggero D, Creti R, Londei P. In vitro translation of archaeal natural mRNAs at high temperature Fems Microbiology Letters. 107: 89-94. DOI: 10.1111/J.1574-6968.1993.Tb06009.X |
0.318 |
|
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