Kelvin H. Lee - Publications

Cornell University, Ithaca, NY, United States 

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Luo Y, Lovelett RJ, Price JV, Radhakrishnan D, Barnthouse K, Hu P, Schaefer E, Cunningham J, Lee KH, Shivappa RB, Ogunnaike BA. Modeling the Effect of Amino Acids and Copper on Monoclonal Antibody Productivity and Glycosylation: A Modular Approach. Biotechnology Journal. e2000261. PMID 32875683 DOI: 10.1002/biot.202000261  0.52
2018 Greene DG, Traylor SJ, Guo J, Choe LH, Modla S, Xu X, Singh N, Lock LL, Ghose S, Li ZJ, Lee KH, Wagner NJ, Lenhoff AM. Mechanisms of precipitate formation during the purification of an Fc-fusion protein. Biotechnology and Bioengineering. PMID 29896879 DOI: 10.1002/bit.26746  0.88
2018 Sawicki LA, Choe LH, Wiley KL, Lee KH, Kloxin AM. Isolation and Identification of Proteins Secreted by Cells Cultured within Synthetic Hydrogel-Based Matrices. Acs Biomaterials Science & Engineering. 4: 836-845. PMID 29552635 DOI: 10.1021/acsbiomaterials.7b00647  0.88
2016 Chiu J, Valente KN, Levy NE, Min L, Lenhoff AM, Lee KH. Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations. Biotechnology and Bioengineering. PMID 27943242 DOI: 10.1002/bit.26237  0.36
2016 Mantle JL, Min L, Lee KH. Minimum Transendothelial Electrical Resistance Thresholds for the Study of Small and Large Molecule Drug Transport in a Human in Vitro Blood-Brain Barrier Model. Molecular Pharmaceutics. 13: 4191-4198. PMID 27934481 DOI: 10.1021/acs.molpharmaceut.6b00818  0.36
2015 Choi YS, Lee KH. Multiple reaction monitoring assay based on conventional liquid chromatography and electrospray ionization for simultaneous monitoring of multiple cerebrospinal fluid biomarker candidates for Alzheimer's disease. Archives of Pharmacal Research. PMID 26404792 DOI: 10.1007/s12272-015-0663-y  0.92
2015 Venkataramanan KP, Min L, Hou S, Jones SW, Ralston MT, Lee KH, Papoutsakis ET. Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum. Biotechnology For Biofuels. 8: 81. PMID 26269711 DOI: 10.1186/s13068-015-0260-9  0.36
2015 Kremkow BG, Baik JY, MacDonald ML, Lee KH. 2.0: Genome resources and website updates. Biotechnology Journal. 10: 931-8. PMID 25923813 DOI: 10.1002/biot.201400646  0.92
2015 Min L, Choe LH, Lee KH. Improved protease digestion conditions for membrane protein detection. Electrophoresis. PMID 25884272 DOI: 10.1002/elps.201400579  0.92
2015 Valente KN, Lenhoff AM, Lee KH. Expression of difficult-to-remove host cell protein impurities during extended Chinese hamster ovary cell culture and their impact on continuous bioprocessing. Biotechnology and Bioengineering. 112: 1232-42. PMID 25502542 DOI: 10.1002/bit.25515  0.92
2014 Dordick JS, Lee KH. Editorial overview: Nanobiotechnology. Current Opinion in Biotechnology. 28: iv-v. PMID 24996481 DOI: 10.1016/j.copbio.2014.06.015  0.92
2014 Baik JY, Lee KH. Toward product attribute control: developments from genome sequencing. Current Opinion in Biotechnology. 30: 40-4. PMID 24874795 DOI: 10.1016/j.copbio.2014.05.001  0.92
2014 Shayan G, Adamiak B, Choe LH, Relkin N, Lee KH. Longitudinal effects of intravenous immunoglobulin on Alzheimer's cerebrospinal fluid proteome. Electrophoresis. 35: 1821-7. PMID 24756957 DOI: 10.1002/elps.201300609  0.88
2014 Baik JY, Lee KH. miRNA expression in CHO: nature knows best. Biotechnology Journal. 9: 459-60. PMID 24519876 DOI: 10.1002/biot.201300503  0.92
2014 Levy NE, Valente KN, Choe LH, Lee KH, Lenhoff AM. Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing. Biotechnology and Bioengineering. 111: 904-12. PMID 24254318 DOI: 10.1002/bit.25158  0.92
2014 Valente KN, Schaefer AK, Kempton HR, Lenhoff AM, Lee KH. Recovery of Chinese hamster ovary host cell proteins for proteomic analysis. Biotechnology Journal. 9: 87-99. PMID 24039059 DOI: 10.1002/biot.201300190  0.92
2013 Choi YS, Hou S, Choe LH, Lee KH. Targeted human cerebrospinal fluid proteomics for the validation of multiple Alzheimer's disease biomarker candidates Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 930: 129-135. PMID 23735279 DOI: 10.1016/j.jchromb.2013.05.003  0.92
2013 Hou S, Jones SW, Choe LH, Papoutsakis ET, Lee KH. Workflow for quantitative proteomic analysis of Clostridium acetobutylicum ATCC 824 using iTRAQ tags. Methods (San Diego, Calif.). 61: 269-76. PMID 23523702 DOI: 10.1016/j.ymeth.2013.03.013  0.92
2013 Wuest DM, Wing AM, Lee KH. Membrane configuration optimization for a murine in vitro blood-brain barrier model. Journal of Neuroscience Methods. 212: 211-21. PMID 23131353 DOI: 10.1016/j.jneumeth.2012.10.016  0.92
2012 Villamil MA, Liang Q, Chen J, Choi YS, Hou S, Lee KH, Zhuang Z. Serine phosphorylation is critical for the activation of ubiquitin-specific protease 1 and its interaction with WD40-repeat protein UAF1. Biochemistry. 51: 9112-23. PMID 23116119 DOI: 10.1021/bi300845s  0.92
2012 Shayan G, Adamiak B, Relkin NR, Lee KH. Longitudinal analysis of novel Alzheimer's disease proteomic cerebrospinal fluid biomarkers during intravenous immunoglobulin therapy. Electrophoresis. 33: 1975-9. PMID 22806462 DOI: 10.1002/elps.201100660  0.56
2012 Valente KN, Choe LH, Lenhoff AM, Lee KH. Optimization of protein sample preparation for two-dimensional electrophoresis. Electrophoresis. 33: 1947-57. PMID 22806459 DOI: 10.1002/elps.201100659  0.92
2012 Gupta P, Swanberg JC, Lee KH. A single nucleotide polymorphism in ycdC alters tRNA synthetase expression and results in hypersecretion in Escherichia coli. Biotechnology Progress. 28: 646-53. PMID 22505047 DOI: 10.1002/btpr.1550  0.6
2012 Shayan G, Felix N, Cho Y, Chatzichristidi M, Shuler ML, Ober CK, Lee KH. Synthesis and characterization of high-throughput nanofabricated poly(4-hydroxy styrene) membranes for in vitro models of barrier tissue. Tissue Engineering. Part C, Methods. 18: 667-76. PMID 22435738 DOI: 10.1089/ten.TEC.2011.0598  0.92
2012 Hammond S, Kaplarevic M, Borth N, Betenbaugh MJ, Lee KH. Chinese hamster genome database: an online resource for the CHO community at Biotechnology and Bioengineering. 109: 1353-6. PMID 22105744 DOI: 10.1002/bit.24374  0.92
2012 Wuest DM, Harcum SW, Lee KH. Genomics in mammalian cell culture bioprocessing. Biotechnology Advances. 30: 629-38. PMID 22079893 DOI: 10.1016/j.biotechadv.2011.10.010  0.92
2012 Munro SA, Choe L, Zinder SH, Lee KH, Walker LP. Proteomic and physiological experiments to test Thermotoga neapolitana constraint-based model hypotheses of carbon source utilization. Biotechnology Progress. 28: 312-8. PMID 22034176 DOI: 10.1002/btpr.735  0.92
2011 Xu X, Nagarajan H, Lewis NE, Pan S, Cai Z, Liu X, Chen W, Xie M, Wang W, Hammond S, Andersen MR, Neff N, Passarelli B, Koh W, Fan HC, ... ... Lee KH, et al. The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nature Biotechnology. 29: 735-41. PMID 21804562 DOI: 10.1038/nbt.1932  0.92
2011 Aggarwal K, Lee KH. Overexpression of cloned RhsA sequences perturbs the cellular translational machinery in Escherichia coli. Journal of Bacteriology. 193: 4869-80. PMID 21764923 DOI: 10.1128/JB.05061-11  1
2011 Shayan G, Shuler ML, Lee KH. The effect of astrocytes on the induction of barrier properties in aortic endothelial cells. Biotechnology Progress. 27: 1137-45. PMID 21626719 DOI: 10.1002/btpr.620  0.92
2011 Wu CY, Curtis A, Choi YS, Maeda M, Xu MJ, Berg A, Joneja U, Mason RW, Lee KH, Wang W. Identification of the phosphorylation sites in the survival motor neuron protein by protein kinase A Biochimica Et Biophysica Acta - Proteins and Proteomics. 1814: 1134-1139. PMID 21609790 DOI: 10.1016/j.bbapap.2011.04.015  0.92
2011 Wu CY, Whye D, Glazewski L, Choe L, Kerr D, Lee KH, Mason RW, Wang W. Proteomic assessment of a cell model of spinal muscular atrophy. Bmc Neuroscience. 12: 25. PMID 21385431 DOI: 10.1186/1471-2202-12-25  0.92
2011 Shayan G, Choi YS, Shusta EV, Shuler ML, Lee KH. Murine in vitro model of the blood-brain barrier for evaluating drug transport. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 42: 148-55. PMID 21078386 DOI: 10.1016/j.ejps.2010.11.005  0.92
2011 Liao PY, Choi YS, Dinman JD, Lee KH. The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed -1 ribosomal frameshifting. Nucleic Acids Research. 39: 300-12. PMID 20823091 DOI: 10.1093/nar/gkq761  0.92
2010 Choi YS, Choe LH, Lee KH. Recent cerebrospinal fluid biomarker studies of Alzheimers disease Expert Review of Proteomics. 7: 919-926. PMID 21142892 DOI: 10.1586/epr.10.75  0.92
2009 Rudrappa T, Choi YS, Levia DF, Legates DR, Lee KH, Bais HP. Phragmites australis root secreted phytotoxin undergoes photo-degradation to execute severe phytotoxicity Plant Signaling and Behavior. 4: 506-513. PMID 19816146 DOI: 10.4161/psb.4.6.8698  0.92
2009 Liao PY, Choi YS, Lee KH. FSscan: A mechanism-based program to identify +1 ribosomal frameshift hotspots Nucleic Acids Research. 37: 7302-7311. PMID 19783813 DOI: 10.1093/nar/gkp796  0.92
2008 Griffiths LG, Choe L, Lee KH, Reardon KF, Orton EC. Protein extraction and 2-DE of water- and lipid-soluble proteins from bovine pericardium, a low-cellularity tissue. Electrophoresis. 29: 4508-15. PMID 18985661 DOI: 10.1002/elps.200800108  0.92
2008 Park SM, Lee KH, Craighead HG. On-chip coupling of electrochemical pumps and an SU-8 tip for electrospray ionization mass spectrometry Biomedical Microdevices. 10: 891-897. PMID 18563570 DOI: 10.1007/s10544-008-9203-6  0.92
2008 Gupta P, Lee KH. Silent mutations result in HlyA hypersecretion by reducing intracellular HlyA protein aggregates. Biotechnology and Bioengineering. 101: 967-74. PMID 18553505 DOI: 10.1002/bit.21979  0.6
2008 Liao PY, Gupta P, Petrov AN, Dinman JD, Lee KH. A new kinetic model reveals the synergistic effect of E-, P- and A-sites on +1 ribosomal frameshifting. Nucleic Acids Research. 36: 2619-29. PMID 18344525 DOI: 10.1093/nar/gkn100  0.92
2007 Choe L, D'Ascenzo M, Relkin NR, Pappin D, Ross P, Williamson B, Guertin S, Pribil P, Lee KH. 8-plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease. Proteomics. 7: 3651-60. PMID 17880003 DOI: 10.1002/pmic.200700316  0.32
2007 Kuczenski RS, Hong KC, García-Ojalvo J, Lee KH. PERIOD-TIMELESS interval timer may require an additional feedback loop Plos Computational Biology. 3: 1468-1476. PMID 17676950 DOI: 10.1371/journal.pcbi.0030154  0.92
2007 Gupta P, Lee KH. Genomics and proteomics in process development: opportunities and challenges. Trends in Biotechnology. 25: 324-30. PMID 17475353 DOI: 10.1016/j.tibtech.2007.04.005  0.6
2007 Finehout EJ, Franck Z, Choe LH, Relkin N, Lee KH. Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease. Annals of Neurology. 61: 120-9. PMID 17167789 DOI: 10.1002/ana.21038  1
2006 Finehout EJ, Franck Z, Relkin N, Lee KH. Proteomic analysis of cerebrospinal fluid changes related to postmortem interval. Clinical Chemistry. 52: 1906-13. PMID 16887899 DOI: 10.1373/clinchem.2006.070508  1
2006 Choe LH, Werner BG, Lee KH. Two-dimensional protein electrophoresis: from molecular pathway discovery to biomarker discovery in neurological disorders. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 327-35. PMID 16815216 DOI: 10.1016/j.nurx.2006.05.001  0.88
2006 Aggarwal K, Choe LH, Lee KH. Shotgun proteomics using the iTRAQ isobaric tags. Briefings in Functional Genomics & Proteomics. 5: 112-20. PMID 16772272 DOI: 10.1093/bfgp/ell018  1
2005 D'Ascenzo M, Relkin NR, Lee KH. Alzheimer's disease cerebrospinal fluid biomarker discovery: a proteomics approach. Current Opinion in Molecular Therapeutics. 7: 557-64. PMID 16372405  0.32
2005 Kuczenski RS, Aggarwal K, Lee KH. Improved understanding of gene expression regulation using systems biology Expert Review of Proteomics. 2: 915-924. PMID 16307520 DOI: 10.1586/14789450.2.6.915  0.92
2005 Yang Y, Li C, Lee KH, Craighead HG. Coupling on-chip solid-phase extraction to electrospray mass spectrometry through an integrated electrospray tip. Electrophoresis. 26: 3622-30. PMID 16136527 DOI: 10.1002/elps.200500121  0.92
2005 Yang Y, Li C, Kameoka J, Lee KH, Craighead HG. A polymeric microchip with integrated tips and in situ polymerized monolith for electrospray mass spectrometry. Lab On a Chip. 5: 869-76. PMID 16027939 DOI: 10.1039/b503025k  0.92
2005 Diao J, Ren D, Engstrom JR, Lee KH. A surface modification strategy on silicon nitride for developing biosensors. Analytical Biochemistry. 343: 322-8. PMID 15993368 DOI: 10.1016/j.ab.2005.05.010  0.92
2005 Choe LH, Aggarwal K, Franck Z, Lee KH. A comparison of the consistency of proteome quantitation using two-dimensional electrophoresis and shotgun isobaric tagging in Escherichia coli cells. Electrophoresis. 26: 2437-49. PMID 15924362 DOI: 10.1002/elps.200410336  1
2005 Finehout EJ, Franck Z, Lee KH. Complement protein isoforms in CSF as possible biomarkers for neurodegenerative disease. Disease Markers. 21: 93-101. PMID 15920296  1
2005 Aggarwal K, Choe LH, Lee KH. Quantitative analysis of protein expression using amine-specific isobaric tags in Escherichia coli cells expressing rhsA elements. Proteomics. 5: 2297-308. PMID 15887184 DOI: 10.1002/pmic.200401231  1
2005 Finehout EJ, Cantor JR, Lee KH. Kinetic characterization of sequencing grade modified trypsin. Proteomics. 5: 2319-21. PMID 15880790 DOI: 10.1002/pmic.200401268  1
2005 Li C, Yang Y, Craighead HG, Lee KH. Isoelectric focusing in cyclic olefin copolymer microfluidic channels coated by polyacrylamide using a UV photografting method. Electrophoresis. 26: 1800-6. PMID 15800962 DOI: 10.1002/elps.200410309  0.92
2005 Hayduk EJ, Lee KH. Cytochalasin D can improve heterologous protein productivity in adherent Chinese hamster ovary cells. Biotechnology and Bioengineering. 90: 354-64. PMID 15772946 DOI: 10.1002/bit.20438  1
2005 Lee PS, Lee KH. Engineering HlyA hypersecretion in Escherichia coli based on proteomic and microarray analyses. Biotechnology and Bioengineering. 89: 195-205. PMID 15580578 DOI: 10.1002/bit.20342  0.88
2004 Finehout EJ, Lee KH. An introduction to mass spectrometry applications in biological research. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 32: 93-100. PMID 21706701 DOI: 10.1002/bmb.2004.494032020331  1
2004 Shaw LB, Sethna JP, Lee KH. Mean-field approaches to the totally asymmetric exclusion process with quenched disorder and large particles. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 70: 021901. PMID 15447509 DOI: 10.1103/PhysRevE.70.021901  0.92
2004 Finehout EJ, Franck Z, Lee KH. Towards two-dimensional electrophoresis mapping of the cerebrospinal fluid proteome from a single individual. Electrophoresis. 25: 2564-75. PMID 15300777 DOI: 10.1002/elps.200406012  1
2004 Hayduk EJ, Choe LH, Lee KH. A two-dimensional electrophoresis map of Chinese hamster ovary cell proteins based on fluorescence staining. Electrophoresis. 25: 2545-56. PMID 15300775 DOI: 10.1002/elps.200406010  1
2003 Aggarwal K, Lee KH. Functional genomics and proteomics as a foundation for systems biology. Briefings in Functional Genomics & Proteomics. 2: 175-84. PMID 15239921  1
2003 Lee PS, Shaw LB, Choe LH, Mehra A, Hatzimanikatis V, Lee KH. Insights into the relation between mrna and protein expression patterns: II. Experimental observations in Escherichia coli. Biotechnology and Bioengineering. 84: 834-41. PMID 14708124 DOI: 10.1002/bit.10841  0.96
2003 Mehra A, Lee KH, Hatzimanikatis V. Insights into the relation between mRNA and protein expression patterns: I. Theoretical considerations. Biotechnology and Bioengineering. 84: 822-33. PMID 14708123 DOI: 10.1002/bit.10860  0.96
2003 Lee PS, Lee KH. Escherichia coli--a model system that benefits from and contributes to the evolution of proteomics. Biotechnology and Bioengineering. 84: 801-14. PMID 14708121 DOI: 10.1002/bit.10848  0.88
2003 Finehout EJ, Lee KH. Comparison of automated in-gel digest methods for femtomole level samples. Electrophoresis. 24: 3508-16. PMID 14595698 DOI: 10.1002/elps.200305615  1
2003 Choe LH, Lee KH. Quantitative and qualitative measure of intralaboratory two-dimensional protein gel reproducibility and the effects of sample preparation, sample load, and image analysis. Electrophoresis. 24: 3500-7. PMID 14595697 DOI: 10.1002/elps.200305614  0.88
2003 Shaw LB, Zia RK, Lee KH. Totally asymmetric exclusion process with extended objects: a model for protein synthesis. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 68: 021910. PMID 14525009 DOI: 10.1103/PhysRevE.68.021910  0.92
2002 Choe LH, Dutt MJ, Relkin N, Lee KH. Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease. Electrophoresis. 23: 2247-51. PMID 12210229 DOI: 10.1002/1522-2683(200207)23:14<2247::AID-ELPS2247>3.0.CO;2-M  0.92
2002 Choe LH, Green A, Knight RS, Thompson EJ, Lee KH. Apolipoprotein E and other cerebrospinal fluid proteins differentiate ante mortem variant Creutzfeldt-Jakob disease from ante mortem sporadic Creutzfeldt-Jakob disease. Electrophoresis. 23: 2242-6. PMID 12210228 DOI: 10.1002/1522-2683(200207)23:14<2242::AID-ELPS2242>3.0.CO;2-F  0.88
2002 Reardon KF, Lee KH, Wittrup KD, Hatzimanikatis V. Jay Bailey as mentor--the students' perspective. Biotechnology and Bioengineering. 79: 484-9. PMID 12209819 DOI: 10.1002/bit.10402  0.96
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