James D. Johnson - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Diabetes
Website:
http://diabetes.ubc.ca/primary-members/dr-james-d-johnson/

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Botezelli JD, Overby P, Lindo L, Wang S, Haïda O, Lim GE, Templeman NM, Pauli JR, Johnson JD. Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 32715748 DOI: 10.1152/ajpendo.00128.2020  0.52
2019 Zhang AMY, Magrill J, de Winter TJJ, Hu X, Skovsø S, Schaeffer DF, Kopp JL, Johnson JD. Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development. Cell Metabolism. PMID 31378465 DOI: 10.1016/j.cmet.2019.07.003  0.36
2019 Petrus P, Fernandez TL, Kwon MM, Huang JL, Lei V, Safikhan NS, Karunakaran S, O'Shannessy DJ, Zheng X, Catrina SB, Albone E, Laine J, Virtanen K, Clee SM, Kieffer TJ, ... ... Johnson JD, et al. Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation. Ebiomedicine. PMID 31221584 DOI: 10.1016/j.ebiom.2019.05.057  0.52
2018 Dommerholt MB, Dionne DA, Hutchinson DF, Kruit JK, Johnson JD. Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage. The Journal of Endocrinology. PMID 29439088 DOI: 10.1530/JOE-17-0505  0.36
2017 Page MM, Skovsø S, Cen H, Chiu AP, Dionne DA, Hutchinson DF, Lim GE, Szabat M, Flibotte S, Sinha S, Nislow C, Rodrigues B, Johnson JD. Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29122848 DOI: 10.1096/fj.201700518R  0.36
2017 Templeman NM, Flibotte S, Chik JHL, Sinha S, Lim GE, Foster LJ, Nislow C, Johnson JD. Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan. Cell Reports. 20: 451-463. PMID 28700945 DOI: 10.1016/j.celrep.2017.06.048  0.52
2017 Templeman NM, Skovsø S, Page MM, Lim GE, Johnson JD. A causal role for hyperinsulinemia in obesity. The Journal of Endocrinology. PMID 28052999 DOI: 10.1530/JOE-16-0449  0.52
2017 Zhang D, Wang F, Lal N, Chiu AP, Wan A, Jia J, Bierende D, Flibotte S, Sinha S, Asadi A, Hu X, Taghizadeh F, Pulinilkunnil T, Nislow C, Vlodavsky I, ... Johnson JD, et al. Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes. Diabetes. 66: 45-57. PMID 27999107 DOI: 10.2337/db16-0761  0.48
2016 D'souza AM, Johnson JD, Clee SM, Kieffer TJ. Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lep(ob/ob) mice. Molecular Metabolism. 5: 1103-1112. PMID 27818936 DOI: 10.1016/j.molmet.2016.09.007  0.52
2016 Latham J, Fong H, Jewett A, Johnson JD, Paranjpe A. Disinfection Efficacy of Current Regenerative Endodontic Protocols in Simulated Necrotic Immature Permanent Teeth. Journal of Endodontics. PMID 27372159 DOI: 10.1016/j.joen.2016.05.004  0.52
2016 Lim GE, Piske M, Lulo JE, Ramshaw HS, Lopez AF, Johnson JD. Ywhaz/14-3-3ζ deletion improves glucose tolerance through a GLP-1-dependent mechanism. Endocrinology. en20161016. PMID 27167773 DOI: 10.1210/en.2016-1016  0.52
2016 Dionne DA, Skovsø S, Templeman NM, Clee SM, Johnson JD. Caloric restriction paradoxically increases adiposity in mice with genetically reduced insulin. Endocrinology. en20161102. PMID 27145011 DOI: 10.1210/en.2016-1102  0.52
2016 Boothe T, Lim GE, Cen H, Skovsø S, Piske M, Li SN, Nabi IR, Gilon P, Johnson JD. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Molecular Metabolism. 5: 366-78. PMID 27110488 DOI: 10.1016/j.molmet.2016.01.009  0.52
2016 Templeman NM, Mehran AE, Johnson JD. Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility. Plos One. 11: e0153280. PMID 27055260 DOI: 10.1371/journal.pone.0153280  0.52
2015 Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, ... ... Johnson JD, et al. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation. Cell Metabolism. PMID 26626461 DOI: 10.1016/j.cmet.2015.10.016  0.52
2015 Machado J, Johnson JD, Paranjpe A. The Effects of Endosequence Root Repair Material on Differentiation of Dental Pulp Cells. Journal of Endodontics. PMID 26410154 DOI: 10.1016/j.joen.2015.08.007  0.52
2015 Weissman J, Johnson JD, Anderson M, Hollender L, Huson T, Paranjpe A, Patel S, Cohenca N. Association between the Presence of Apical Periodontitis and Clinical Symptoms in Endodontic Patients Using Cone-beam Computed Tomography and Periapical Radiographs. Journal of Endodontics. PMID 26349581 DOI: 10.1016/j.joen.2015.06.004  0.52
2015 Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD. 14-3-3ζ coordinates adipogenesis of visceral fat. Nature Communications. 6: 7671. PMID 26220403 DOI: 10.1038/ncomms8671  0.52
2015 Templeman NM, Clee SM, Johnson JD. Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity. Diabetologia. PMID 26155745 DOI: 10.1007/s00125-015-3676-7  0.52
2015 Yang YH, Wills QF, Johnson JD. A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells. Diabetologia. 58: 1239-49. PMID 25773404 DOI: 10.1007/s00125-015-3552-5  0.52
2015 Albrecht T, Zhao Y, Nguyen TH, Campbell RE, Johnson JD. Fluorescent biosensors illuminate calcium levels within defined beta-cell endosome subpopulations. Cell Calcium. 57: 263-74. PMID 25682167 DOI: 10.1016/j.ceca.2015.01.008  0.52
2015 Ho MM, Johnson JD, Clee SM. PWD/PhJ mice have a genetically determined increase in nutrient-stimulated insulin secretion. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 26: 131-41. PMID 25605412 DOI: 10.1007/s00335-015-9554-2  0.52
2015 Albu RF, Chan GT, Zhu M, Wong ET, Taghizadeh F, Hu X, Mehran AE, Johnson JD, Gsponer J, Mayor T. A feature analysis of lower solubility proteins in three eukaryotic systems. Journal of Proteomics. 118: 21-38. PMID 25451012 DOI: 10.1016/j.jprot.2014.10.011  0.52
2014 Chan MT, Lim GE, Skovsø S, Yang YH, Albrecht T, Alejandro EU, Hoesli CA, Piret JM, Warnock GL, Johnson JD. Effects of insulin on human pancreatic cancer progression modeled in vitro. Bmc Cancer. 14: 814. PMID 25373319 DOI: 10.1186/1471-2407-14-814  0.52
2014 Johnson JD. A practical guide to genetic engineering of pancreatic β-cells in vivo: getting a grip on RIP and MIP. Islets. 6: e944439. PMID 25322827 DOI: 10.4161/19382014.2014.944439  0.52
2014 Rezania A, Bruin JE, Arora P, Rubin A, Batushansky I, Asadi A, O'Dwyer S, Quiskamp N, Mojibian M, Albrecht T, Yang YH, Johnson JD, Kieffer TJ. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nature Biotechnology. 32: 1121-33. PMID 25211370 DOI: 10.1038/nbt.3033  0.52
2014 Nguyen HH, Fong H, Paranjpe A, Flake NM, Johnson JD, Peters OA. Evaluation of the resistance to cyclic fatigue among ProTaper Next, ProTaper Universal, and Vortex Blue rotary instruments. Journal of Endodontics. 40: 1190-3. PMID 25069931 DOI: 10.1016/j.joen.2013.12.033  0.52
2014 Liu Y, Wang R, Sun B, Mi T, Zhang J, Mu Y, Chen J, Bround MJ, Johnson JD, Gillis AM, Chen SR. Generation and characterization of a mouse model harboring the exon-3 deletion in the cardiac ryanodine receptor. Plos One. 9: e95615. PMID 24743769 DOI: 10.1371/journal.pone.0095615  0.52
2014 Ho MM, Hu X, Karunakaran S, Johnson JD, Clee SM. Altered pancreatic growth and insulin secretion in WSB/EiJ mice. Plos One. 9: e88352. PMID 24505481 DOI: 10.1371/journal.pone.0088352  0.52
2014 D'souza AM, Asadi A, Johnson JD, Covey SD, Kieffer TJ. Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis. Endocrinology. 155: 1268-79. PMID 24467741 DOI: 10.1210/en.2013-1523  0.52
2014 Yang YH, Vilin YY, Roberge M, Kurata HT, Johnson JD. Multiparameter screening reveals a role for Na+ channels in cytokine-induced β-cell death. Molecular Endocrinology (Baltimore, Md.). 28: 406-17. PMID 24438339 DOI: 10.1210/me.2013-1257  0.52
2014 McRay B, Cox TC, Cohenca N, Johnson JD, Paranjpe A. A micro-computed tomography-based comparison of the canal transportation and centering ability of ProTaper Universal rotary and WaveOne reciprocating files. Quintessence International (Berlin, Germany : 1985). 45: 101-8. PMID 24389561 DOI: 10.3290/j.qi.a30998  0.52
2014 Bruin JE, Erener S, Vela J, Hu X, Johnson JD, Kurata HT, Lynn FC, Piret JM, Asadi A, Rezania A, Kieffer TJ. Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells. Stem Cell Research. 12: 194-208. PMID 24257076 DOI: 10.1016/j.scr.2013.10.003  0.52
2013 Szabat M, Johnson JD. Modulation of β-cell fate and function by TGFβ ligands: a superfamily with many powers. Endocrinology. 154: 3965-9. PMID 24141995 DOI: 10.1210/en.2013-1880  0.52
2013 Zhang D, Wan A, Chiu AP, Wang Y, Wang F, Neumaier K, Lal N, Bround MJ, Johnson JD, Vlodavsky I, Rodrigues B. Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2830-8. PMID 24115032 DOI: 10.1161/ATVBAHA.113.302222  0.52
2013 Yang YH, Manning Fox JE, Zhang KL, MacDonald PE, Johnson JD. Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 110: 16480-5. PMID 24065825 DOI: 10.1073/pnas.1214312110  0.52
2013 Tudurí E, Bruin JE, Denroche HC, Fox JK, Johnson JD, Kieffer TJ. Impaired Ca(2+) signaling in β-cells lacking leptin receptors by Cre-loxP recombination. Plos One. 8: e71075. PMID 23936486 DOI: 10.1371/journal.pone.0071075  0.52
2013 Yang YH, Johnson JD. Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic β-cells. Journal of Cell Science. 126: 4286-95. PMID 23843629 DOI: 10.1242/jcs.133017  0.52
2013 Wang M, Li J, Lim GE, Johnson JD. Is dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets. Plos One. 8: e64860. PMID 23798995 DOI: 10.1371/journal.pone.0064860  0.52
2013 Bround MJ, Wambolt R, Luciani DS, Kulpa JE, Rodrigues B, Brownsey RW, Allard MF, Johnson JD. Cardiomyocyte ATP production, metabolic flexibility, and survival require calcium flux through cardiac ryanodine receptors in vivo. The Journal of Biological Chemistry. 288: 18975-86. PMID 23678000 DOI: 10.1074/jbc.M112.427062  0.52
2013 Cohenca N, Paranjpe A, Heilborn C, Johnson JD. Antimicrobial efficacy of two irrigation techniques in tapered and non-tapered canal preparations. A randomized controlled clinical trial. Quintessence International (Berlin, Germany : 1985). 44: 217-28. PMID 23444203 DOI: 10.3290/j.qi.a29055  0.52
2013 Ho MM, Yoganathan P, Chu KY, Karunakaran S, Johnson JD, Clee SM. Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets. Bmc Genetics. 14: 10. PMID 23442068 DOI: 10.1186/1471-2156-14-10  0.52
2013 Luciani DS, White SA, Widenmaier SB, Saran VV, Taghizadeh F, Hu X, Allard MF, Johnson JD. Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic β-cells. Diabetes. 62: 170-82. PMID 22933114 DOI: 10.2337/db11-1464  0.52
2012 Mehran AE, Templeman NM, Brigidi GS, Lim GE, Chu KY, Hu X, Botezelli JD, Asadi A, Hoffman BG, Kieffer TJ, Bamji SX, Clee SM, Johnson JD. Hyperinsulinemia drives diet-induced obesity independently of brain insulin production. Cell Metabolism. 16: 723-37. PMID 23217255 DOI: 10.1016/j.cmet.2012.10.019  0.52
2012 Paranjpe A, Jain S, Alibhai KJ, Wadhwani CP, Darveau RP, Johnson JD. In vitro microbiologic evaluation of PTFE and cotton as spacer materials. Quintessence International (Berlin, Germany : 1985). 43: 703-7. PMID 23034423  0.52
2012 Bround MJ, Asghari P, Wambolt RB, Bohunek L, Smits C, Philit M, Kieffer TJ, Lakatta EG, Boheler KR, Moore ED, Allard MF, Johnson JD. Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice. Cardiovascular Research. 96: 372-80. PMID 22869620 DOI: 10.1093/cvr/cvs260  0.52
2012 Yamamura B, Cox TC, Heddaya B, Flake NM, Johnson JD, Paranjpe A. Comparing canal transportation and centering ability of endosequence and vortex rotary files by using micro-computed tomography. Journal of Endodontics. 38: 1121-5. PMID 22794219 DOI: 10.1016/j.joen.2012.04.019  0.52
2012 Szabat M, Lynn FC, Hoffman BG, Kieffer TJ, Allan DW, Johnson JD. Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiology. Diabetes. 61: 1365-71. PMID 22618775 DOI: 10.2337/db11-1361  0.52
2012 Kruit JK, Wijesekara N, Westwell-Roper C, Vanmierlo T, de Haan W, Bhattacharjee A, Tang R, Wellington CL, LütJohann D, Johnson JD, Brunham LR, Verchere CB, Hayden MR. Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function. Diabetes. 61: 659-64. PMID 22315310 DOI: 10.2337/db11-1341  0.52
2012 Duddy FA, Weissman J, Lee RA, Paranjpe A, Johnson JD, Cohenca N. Influence of different types of mouthguards on strength and performance of collegiate athletes: a controlled-randomized trial. Dental Traumatology : Official Publication of International Association For Dental Traumatology. 28: 263-7. PMID 22272945 DOI: 10.1111/j.1600-9657.2011.01106.x  0.52
2012 Kwan SC, Johnson JD, Cohenca N. The effect of splint material and thickness on tooth mobility after extraction and replantation using a human cadaveric model. Dental Traumatology : Official Publication of International Association For Dental Traumatology. 28: 277-81. PMID 22107132 DOI: 10.1111/j.1600-9657.2011.01086.x  0.52
2012 Johnson JD, Bround MJ, White SA, Luciani DS. Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival. Protoplasma. 249: S49-58. PMID 22105567 DOI: 10.1007/s00709-011-0349-3  0.52
2011 Paranjpe A, Smoot T, Zhang H, Johnson JD. Direct contact with mineral trioxide aggregate activates and differentiates human dental pulp cells. Journal of Endodontics. 37: 1691-5. PMID 22099907 DOI: 10.1016/j.joen.2011.09.012  0.52
2011 Kruit JK, Wijesekara N, Fox JE, Dai XQ, Brunham LR, Searle GJ, Morgan GP, Costin AJ, Tang R, Bhattacharjee A, Johnson JD, Light PE, Marsh BJ, Macdonald PE, Verchere CB, et al. Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules. Diabetes. 60: 3186-96. PMID 21998401 DOI: 10.2337/db11-0081  0.52
2011 Alejandro EU, Lim GE, Mehran AE, Hu X, Taghizadeh F, Pelipeychenko D, Baccarini M, Johnson JD. Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3884-95. PMID 21817126 DOI: 10.1096/fj.10-180349  0.52
2011 Gatten DL, Riedy CA, Hong SK, Johnson JD, Cohenca N. Quality of life of endodontically treated versus implant treated patients: a University-based qualitative research study. Journal of Endodontics. 37: 903-9. PMID 21689542 DOI: 10.1016/j.joen.2011.03.026  0.52
2011 Gallo M, Park D, Luciani DS, Kida K, Palmieri F, Blacque OE, Johnson JD, Riddle DL. MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. Plos One. 6: e17827. PMID 21448454 DOI: 10.1371/journal.pone.0017827  0.52
2011 Wiseman A, Cox TC, Paranjpe A, Flake NM, Cohenca N, Johnson JD. Efficacy of sonic and ultrasonic activation for removal of calcium hydroxide from mesial canals of mandibular molars: a microtomographic study. Journal of Endodontics. 37: 235-8. PMID 21238809 DOI: 10.1016/j.joen.2010.11.019  0.52
2010 Hutton MJ, Soukhatcheva G, Johnson JD, Verchere CB. Role of the TLR signaling molecule TRIF in β-cell function and glucose homeostasis. Islets. 2: 104-11. PMID 21099302 DOI: 10.4161/isl.2.2.11209  0.52
2010 Hill JA, Szabat M, Hoesli CA, Gage BK, Yang YH, Williams DE, Riedel MJ, Luciani DS, Kalynyak TB, Tsai K, Ao Z, Andersen RJ, Warnock GL, Piret JM, Kieffer TJ, ... Johnson JD, et al. A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression. Plos One. 5: e12958. PMID 20886041 DOI: 10.1371/journal.pone.0012958  0.52
2010 Chu KY, Lin Y, Hendel A, Kulpa JE, Brownsey RW, Johnson JD. ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells. The Journal of Biological Chemistry. 285: 32606-15. PMID 20693577 DOI: 10.1074/jbc.M110.157172  0.52
2010 Paranjpe A, Zhang H, Johnson JD. Effects of mineral trioxide aggregate on human dental pulp cells after pulp-capping procedures. Journal of Endodontics. 36: 1042-7. PMID 20478462 DOI: 10.1016/j.joen.2010.02.013  0.52
2010 Alejandro EU, Kalynyak TB, Taghizadeh F, Gwiazda KS, Rawstron EK, Jacob KJ, Johnson JD. Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways. Endocrinology. 151: 502-12. PMID 20056832 DOI: 10.1210/en.2009-0678  0.52
2009 Fujimoto K, Hanson PT, Tran H, Ford EL, Han Z, Johnson JD, Schmidt RE, Green KG, Wice BM, Polonsky KS. Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation. The Journal of Biological Chemistry. 284: 27664-73. PMID 19654319 DOI: 10.1074/jbc.M109.041616  0.52
2009 Gwiazda KS, Yang TL, Lin Y, Johnson JD. Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells. American Journal of Physiology. Endocrinology and Metabolism. 296: E690-701. PMID 19141690 DOI: 10.1152/ajpendo.90525.2008  0.48
2009 Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD. Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death. Diabetes. 58: 422-32. PMID 19033399 DOI: 10.2337/db07-1762  0.48
2008 Jeffrey KD, Alejandro EU, Luciani DS, Kalynyak TB, Hu X, Li H, Lin Y, Townsend RR, Polonsky KS, Johnson JD. Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 8452-7. PMID 18550819 DOI: 10.1073/pnas.0711232105  0.92
2008 Johnson JD, Alejandro EU. Control of pancreatic beta-cell fate by insulin signaling: The sweet spot hypothesis. Cell Cycle (Georgetown, Tex.). 7: 1343-7. PMID 18418065  0.92
2008 Beith JL, Alejandro EU, Johnson JD. Insulin stimulates primary beta-cell proliferation via Raf-1 kinase. Endocrinology. 149: 2251-60. PMID 18202127 DOI: 10.1210/en.2007-1557  0.92
2008 Alejandro EU, Johnson JD. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. The Journal of Biological Chemistry. 283: 2407-17. PMID 18006502 DOI: 10.1074/jbc.M703612200  0.92
2006 Johnson JD, Bernal-Mizrachi E, Alejandro EU, Han Z, Kalynyak TB, Li H, Beith JL, Gross J, Warnock GL, Townsend RR, Permutt MA, Polonsky KS. Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proceedings of the National Academy of Sciences of the United States of America. 103: 19575-80. PMID 17158802 DOI: 10.1073/pnas.0604208103  0.92
2004 Johnson JD, Han Z, Otani K, Ye H, Zhang Y, Wu H, Horikawa Y, Misler S, Bell GI, Polonsky KS. RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. The Journal of Biological Chemistry. 279: 24794-802. PMID 15044459 DOI: 10.1074/jbc.M401216200  0.52
2004 Johnson JD, Kuang S, Misler S, Polonsky KS. Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 878-80. PMID 15033925 DOI: 10.1096/fj.03-1280fje  0.52
2003 Johnson JD, Ahmed NT, Luciani DS, Han Z, Tran H, Fujita J, Misler S, Edlund H, Polonsky KS. Increased islet apoptosis in Pdx1+/- mice. The Journal of Clinical Investigation. 111: 1147-60. PMID 12697734 DOI: 10.1172/JCI16537  0.52
2002 Johnson JD, Misler S. Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 14566-71. PMID 12381785 DOI: 10.1073/pnas.222099799  0.52
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