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Santiago Schnell, DPhil (Oxon) - Publications

Affiliations: 
2008- Molecular & Integrative Physiology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Mathematical biology
Website:
http://www.med.umich.edu/schnell-lab/
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Eilertsen J, Stroberg W, Schnell S. Characteristic, completion or matching timescales? An analysis of temporary boundaries in enzyme kinetics. Journal of Theoretical Biology. PMID 30615881 DOI: 10.1016/J.Jtbi.2019.01.005  0.333
2018 Eilertsen J, Schnell S. A Kinetic Analysis of Coupled (or Auxiliary) Enzyme Reactions. Bulletin of Mathematical Biology. 80: 3154-3183. PMID 30288641 DOI: 10.1007/S11538-018-0513-4  0.304
2018 Eilertsen J, Stroberg W, Schnell S. Phase-plane geometries in coupled enzyme assays. Mathematical Biosciences. 306: 126-135. PMID 30261179 DOI: 10.1016/J.Mbs.2018.09.008  0.314
2018 Eilertsen J, Stroberg W, Schnell S. A theory of reactant-stationary kinetics for a mechanism of zymogen activation. Biophysical Chemistry. 242: 34-44. PMID 30218978 DOI: 10.1016/J.Bpc.2018.08.003  0.309
2018 Stroberg W, Schnell S. Do Cellular Condensates Accelerate Biochemical Reactions? Lessons from Microdroplet Chemistry. Biophysical Journal. 115: 3-8. PMID 29972809 DOI: 10.1016/J.Bpj.2018.05.023  0.334
2017 Wynn ML, Egbert M, Consul N, Chang J, Wu ZF, Meravjer SD, Schnell S. Inferring Intracellular Signal Transduction Circuitry from Molecular Perturbation Experiments. Bulletin of Mathematical Biology. PMID 28455685 DOI: 10.1007/S11538-017-0270-9  0.341
2016 Shoffner SK, Schnell S. Estimation of the lag time in a subsequent monomer addition model for fibril elongation. Physical Chemistry Chemical Physics : Pccp. 18: 21259-68. PMID 27250246 DOI: 10.1039/C5Cp07845H  0.331
2014 Mourão MA, Hakim JB, Schnell S. Connecting the dots: the effects of macromolecular crowding on cell physiology. Biophysical Journal. 107: 2761-6. PMID 25517143 DOI: 10.1016/J.Bpj.2014.10.051  0.306
2014 Wynn ML, Consul N, Merajver SD, Schnell S. Inferring the Effects of Honokiol on the Notch Signaling Pathway in SW480 Colon Cancer Cells. Cancer Informatics. 13: 1-12. PMID 25392689 DOI: 10.4137/Cin.S14060  0.309
2014 Whidden M, Ho A, Ivanova MI, Schnell S. Competitive inhibition reaction mechanisms for the two-step model of protein aggregation. Biophysical Chemistry. 193: 9-19. PMID 25048259 DOI: 10.1016/J.Bpc.2014.06.006  0.31
2014 Carulli AJ, Samuelson LC, Schnell S. Unraveling intestinal stem cell behavior with models of crypt dynamics. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 243-57. PMID 24480852 DOI: 10.1039/C3Ib40163D  0.305
2014 Grima R, Walter NG, Schnell S. Single-molecule enzymology à la Michaelis-Menten. The Febs Journal. 281: 518-30. PMID 24289171 DOI: 10.1111/Febs.12663  0.331
2014 Egbert ME, Wynn ML, Wu ZF, Gilani RA, Schnell S, Merajver SD. Abstract 357: A systems biology approach for rational molecular network inference Cancer Research. 74: 357-357. DOI: 10.1158/1538-7445.Am2014-357  0.345
2014 Schnell S. Protein Interactions and Transition Times that Influence the Pathogenesis of Protein Folding Diseases Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.257  0.313
2013 Sandefur CI, Mincheva M, Schnell S. Network representations and methods for the analysis of chemical and biochemical pathways Molecular Biosystems. 9: 2189-2200. PMID 23857078 DOI: 10.1039/C3Mb70052F  0.714
2013 Wynn ML, Egbert M, Wassenhove LDV, Wu ZF, Midani F, Evans C, Burant CF, Schnell S, Merajver SD. Abstract 5239: Unraveling the complex regulatory relationship between PI3K signaling and metabolic transformation in breast cancer. Cancer Research. 73: 5239-5239. DOI: 10.1158/1538-7445.Am2013-5239  0.304
2012 Wynn ML, Consul N, Merajver SD, Schnell S. Logic-based models in systems biology: a predictive and parameter-free network analysis method. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1323-37. PMID 23072820 DOI: 10.1039/C2Ib20193C  0.355
2011 Mourão MA, Srividhya J, McSharry PE, Crampin EJ, Schnell S. A graphical user interface for a method to infer kinetics and network architecture (MIKANA). Plos One. 6: e27534. PMID 22096591 DOI: 10.1371/Journal.Pone.0027534  0.357
2011 Sandefur CI, Schnell S. A model of threshold behavior reveals rescue mechanisms of bystander proteins in conformational diseases Biophysical Journal. 100: 1864-1873. PMID 21504722 DOI: 10.1016/J.Bpj.2011.03.006  0.708
2010 Srividhya J, Mourão MA, Crampin EJ, Schnell S. Enzyme catalyzed reactions: From experiment to computational mechanism reconstruction Computational Biology and Chemistry. 34: 11-18. PMID 19945917 DOI: 10.1016/J.Compbiolchem.2009.10.007  0.342
2008 Grima R, Schnell S. Modelling reaction kinetics inside cells. Essays in Biochemistry. 45: 41-56. PMID 18793122 DOI: 10.1042/Bse0450041  0.332
2008 Hanson SM, Schnell S. Reactant stationary approximation in enzyme kinetics. The Journal of Physical Chemistry. A. 112: 8654-8. PMID 18714952 DOI: 10.1021/Jp8026226  0.316
2008 Baker RE, Schnell S, Maini PK. Mathematical models for somite formation. Current Topics in Developmental Biology. 81: 183-203. PMID 18023728 DOI: 10.1016/S0070-2153(07)81006-4  0.309
2007 Srividhya J, Crampin EJ, McSharry PE, Schnell S. Reconstructing biochemical pathways from time course data Proteomics. 7: 828-838. PMID 17370261 DOI: 10.1002/Pmic.200600428  0.346
2007 Schnell S, Fortunato S, Roy S. Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks? Proteomics. 7: 961-4. PMID 17285562 DOI: 10.1002/Pmic.200600455  0.312
2007 Srividhya J, Gopinathan MS, Schnell S. The effects of time delays in a phosphorylation-dephosphorylation pathway Biophysical Chemistry. 125: 286-297. PMID 17014949 DOI: 10.1016/J.Bpc.2006.09.001  0.312
2007 Grima R, Schnell S. A mesoscopic simulation approach for modeling intracellular reactions Journal of Statistical Physics. 128: 139-164. DOI: 10.1007/S10955-006-9202-Z  0.331
2006 Roy S, Schnell S, Radivojac P. Unraveling the nature of the segmentation clock: Intrinsic disorder of clock proteins and their interaction map. Computational Biology and Chemistry. 30: 241-8. PMID 16798096 DOI: 10.1016/J.Compbiolchem.2006.04.005  0.313
2006 Grima R, Schnell S. A systematic investigation of the rate laws valid in intracellular environments Biophysical Chemistry. 124: 1-10. PMID 16781049 DOI: 10.1016/J.Bpc.2006.04.019  0.315
2006 Srividhya J, Schnell S. Why substrate depletion has apparent first-order kinetics in enzymatic digestion Computational Biology and Chemistry. 30: 209-214. PMID 16651027 DOI: 10.1016/J.Compbiolchem.2006.03.003  0.334
2006 Baker RE, Schnell S, Maini PK. A clock and wavefront mechanism for somite formation. Developmental Biology. 293: 116-26. PMID 16546158 DOI: 10.1016/J.Ydbio.2006.01.018  0.31
2006 Baker RE, Schnell S, Maini PK. A mathematical investigation of a Clock and Wavefront model for somitogenesis. Journal of Mathematical Biology. 52: 458-82. PMID 16463189 DOI: 10.1007/S00285-005-0362-2  0.306
2006 Schnell S, Chappell MJ, Evans ND, Roussel MR. The mechanism distinguishability problem in biochemical kinetics: The single-enzyme, single-substrate reaction as a case study Comptes Rendus - Biologies. 329: 51-61. PMID 16399643 DOI: 10.1016/J.Crvi.2005.09.005  0.331
2004 Crampin EJ, Schnell S, McSharry PE. Mathematical and computational techniques to deduce complex biochemical reaction mechanisms Progress in Biophysics and Molecular Biology. 86: 77-112. PMID 15261526 DOI: 10.1016/J.Pbiomolbio.2004.04.002  0.344
2004 Crampin EJ, Schnell S. New approaches to modelling and analysis of biochemical reactions, pathways and networks Progress in Biophysics and Molecular Biology. 86: 1-4. PMID 15261523 DOI: 10.1016/J.Pbiomolbio.2004.04.001  0.342
2004 Turner TE, Schnell S, Burrage K. Stochastic approaches for modelling in vivo reactions Computational Biology and Chemistry. 28: 165-178. PMID 15261147 DOI: 10.1016/J.Compbiolchem.2004.05.001  0.33
2004 Schnell S, Turner TE. Reaction kinetics in intracellular environments with macromolecular crowding: Simulations and rate laws Progress in Biophysics and Molecular Biology. 85: 235-260. PMID 15142746 DOI: 10.1016/J.Pbiomolbio.2004.01.012  0.328
2004 Hinch R, Schnell S. Mechanism equivalence in enzyme-substrate reactions: Distributed differential delay in enzyme kinetics Journal of Mathematical Chemistry. 35: 253-264. DOI: 10.1023/B:Jomc.0000033258.42803.60  0.317
2003 Baker RE, Schnell S, Maini PK. Formation of vertebral precursors: Past models and future predictions Journal of Theoretical Medicine. 5: 23-35. DOI: 10.1080/10273660310001628365  0.328
2002 Schnell S, Maini PK, McInerney D, Gavaghan DJ, Houston P. Models for pattern formation in somitogenesis: a marriage of cellular and molecular biology. Comptes Rendus Biologies. 325: 179-89. PMID 12017765 DOI: 10.1016/S1631-0691(01)01418-4  0.332
2001 Schnell S, Maini PK. Enzyme kinetics far from the standard quasi-steady-state and equilibrium approximations Mathematical and Computer Modelling. 35: 137-144. DOI: 10.1016/S0895-7177(01)00156-X  0.307
2000 Collier JR, Mcinerney D, Schnell S, Maini PK, Gavaghan DJ, Houston P, Stern CD. A cell cycle model for somitogenesis: mathematical formulation and numerical simulation. Journal of Theoretical Biology. 207: 305-16. PMID 11082301 DOI: 10.1006/Jtbi.2000.2172  0.311
2000 Schnell S, Mendoza C. Time-dependent closed form solutions for fully competitive enzyme reactions Bulletin of Mathematical Biology. 62: 321-336. PMID 10824432 DOI: 10.1006/Bulm.1999.0156  0.316
2000 Schnell S, Maini PK. Enzyme kinetics at high enzyme concentration. Bulletin of Mathematical Biology. 62: 483-99. PMID 10812718 DOI: 10.1006/Bulm.1999.0163  0.308
2000 Schnell S, Maini PK. Clock and induction model for somitogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 217: 415-20. PMID 10767085 DOI: 10.1002/(Sici)1097-0177(200004)217:4<415::Aid-Dvdy8>3.0.Co;2-3  0.3
2000 Schnell S, Mendoza C. Enzyme kinetics of multiple alternative substrates Journal of Mathematical Chemistry. 27: 155-170. DOI: 10.1023/A:1019139423811  0.318
1997 Schnell S, Mendoza C. Theoretical description of the polymerase chain reaction Journal of Theoretical Biology. 188: 313-318. PMID 9344735 DOI: 10.1006/Jtbi.1997.0473  0.305
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