| Year |
Citation |
Score |
| 2014 |
Dreyton CJ, Knuckley B, Jones JE, Lewallen DM, Thompson PR. Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism. Biochemistry. 53: 4426-33. PMID 24989433 DOI: 10.1021/Bi500554B |
0.745 |
|
| 2013 |
Foyn H, Jones JE, Lewallen D, Narawane R, Varhaug JE, Thompson PR, Arnesen T. Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. Acs Chemical Biology. 8: 1121-7. PMID 23557624 DOI: 10.1021/Cb400136S |
0.626 |
|
| 2012 |
Jones JE, Slack JL, Fang P, Zhang X, Subramanian V, Causey CP, Coonrod SA, Guo M, Thompson PR. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. Acs Chemical Biology. 7: 160-5. PMID 22004374 DOI: 10.1021/Cb200258Q |
0.78 |
|
| 2011 |
Causey CP, Jones JE, Slack JL, Kamei D, Jones LE, Subramanian V, Knuckley B, Ebrahimi P, Chumanevich AA, Luo Y, Hashimoto H, Sato M, Hofseth LJ, Thompson PR. The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. Journal of Medicinal Chemistry. 54: 6919-35. PMID 21882827 DOI: 10.1021/Jm2008985 |
0.727 |
|
| 2011 |
Obianyo O, Causey CP, Jones JE, Thompson PR. Activity-based protein profiling of protein arginine methyltransferase 1. Acs Chemical Biology. 6: 1127-35. PMID 21838253 DOI: 10.1021/Cb2001473 |
0.752 |
|
| 2011 |
Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ. Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G929-38. PMID 21415415 DOI: 10.1152/Ajpgi.00435.2010 |
0.722 |
|
| 2010 |
Jones JE, Dreyton CJ, Flick H, Causey CP, Thompson PR. Mechanistic studies of agmatine deiminase from multiple bacterial species. Biochemistry. 49: 9413-23. PMID 20939536 DOI: 10.1021/Bi101405Y |
0.734 |
|
| 2010 |
Knuckley B, Jones JE, Bachovchin DA, Slack J, Causey CP, Brown SJ, Rosen H, Cravatt BF, Thompson PR. A fluopol-ABPP HTS assay to identify PAD inhibitors. Chemical Communications (Cambridge, England). 46: 7175-7. PMID 20740228 DOI: 10.1039/C0Cc02634D |
0.738 |
|
| 2010 |
Obianyo O, Causey CP, Osborne TC, Jones JE, Lee YH, Stallcup MR, Thompson PR. A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation. Chembiochem : a European Journal of Chemical Biology. 11: 1219-23. PMID 20480486 DOI: 10.1002/Cbic.201000209 |
0.778 |
|
| 2010 |
Knuckley B, Causey CP, Jones JE, Bhatia M, Dreyton CJ, Osborne TC, Takahara H, Thompson PR. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry. 49: 4852-63. PMID 20469888 DOI: 10.1021/Bi100363T |
0.771 |
|
| 2010 |
Jones JE, Causey CP, Lovelace L, Knuckley B, Flick H, Lebioda L, Thompson PR. Characterization and inactivation of an agmatine deiminase from Helicobacter pylori. Bioorganic Chemistry. 38: 62-73. PMID 20036411 DOI: 10.1016/J.Bioorg.2009.11.004 |
0.733 |
|
| 2009 |
Jones JE, Causey CP, Knuckley B, Slack-Noyes JL, Thompson PR. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential Current Opinion in Drug Discovery and Development. 12: 616-627. PMID 19736621 |
0.729 |
|
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