Rong Chen - Publications

Affiliations: 
2004 Boston University, Boston, MA, United States 

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sun M, Shankar R, Ko M, Chang CD, Yeh SJ, Li S, Liu K, Zhou G, Xing J, VanVelsen A, VanVelsen T, Paithankar S, Feng BY, Young K, Strug M, ... ... Chen R, et al. Sex differences in viral entry protein expression, host responses to SARS-CoV-2, and in vitro responses to sex steroid hormone treatment in COVID-19. Research Square. PMID 33173861 DOI: 10.21203/rs.3.rs-100914/v1  0.501
2020 Wang Z, Zheutlin A, Kao YH, Ayers K, Gross S, Kovatch P, Nirenberg S, Charney A, Nadkarni G, De Freitas JK, O'Reilly P, Just A, Horowitz C, Martin G, Branch A, ... ... Chen R, et al. Hospitalised COVID-19 patients of the Mount Sinai Health System: a retrospective observational study using the electronic medical records. Bmj Open. 10: e040441. PMID 33109676 DOI: 10.1136/bmjopen-2020-040441  0.468
2020 Chan L, Chaudhary K, Saha A, Chauhan K, Vaid A, Zhao S, Paranjpe I, Somani S, Richter F, Miotto R, Lala A, Kia A, Timsina P, Li L, Freeman R, ... Chen R, et al. AKI in Hospitalized Patients with COVID-19. Journal of the American Society of Nephrology : Jasn. PMID 32883700 DOI: 10.1681/Asn.2020050615  0.521
2020 Chan L, Chaudhary K, Saha A, Chauhan K, Vaid A, Baweja M, Campbell K, Chun N, Chung M, Deshpande P, Farouk SS, Kaufman L, Kim T, Koncicki H, Lapsia V, ... ... Chen R, et al. Acute Kidney Injury in Hospitalized Patients with COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 32511564 DOI: 10.1101/2020.05.04.20090944  0.464
2019 Glicksberg BS, Amadori L, Akers NK, Sukhavasi K, Franzén O, Li L, Belbin GM, Ayers KL, Shameer K, Badgeley MA, Johnson KW, Readhead B, Darrow BJ, Kenny EE, Betsholtz C, ... ... Chen R, et al. Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits. Bmc Medical Genomics. 12: 154. PMID 31684948 DOI: 10.1186/s12920-019-0573-9  0.668
2019 Glicksberg BS, Amadori L, Akers NK, Sukhavasi K, Franzén O, Li L, Belbin GM, Akers KL, Shameer K, Badgeley MA, Johnson KW, Readhead B, Darrow BJ, Kenny EE, Betsholtz C, ... ... Chen R, et al. Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits. Bmc Medical Genomics. 12: 108. PMID 31345219 DOI: 10.1186/S12920-019-0542-3  0.699
2019 Xu K, Kosoy R, Shameer K, Kumar S, Liu L, Readhead B, Belbin GM, Lee HC, Chen R, Dudley JT. Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans. Bmc Genetics. 20: 52. PMID 31266448 DOI: 10.1186/S12863-019-0758-4  0.55
2019 Bangi E, Ang C, Smibert P, Uzilov AV, Teague AG, Antipin Y, Chen R, Hecht C, Gruszczynski N, Yon WJ, Malyshev D, Laspina D, Selkridge I, Rainey H, Moe AS, et al. A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer. Science Advances. 5: eaav6528. PMID 31131321 DOI: 10.1126/Sciadv.Aav6528  0.317
2019 Lussier YA, Butte AJ, Li H, Chen R, Moore JH. Translational informatics of population health: How large biomolecular and clinical datasets unite. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 24: 455-459. PMID 30864347  0.455
2019 Glicksberg BS, Li L, Chen R, Dudley J, Chen B. Leveraging Big Data to Transform Drug Discovery. Methods in Molecular Biology (Clifton, N.J.). 1939: 91-118. PMID 30848458 DOI: 10.1007/978-1-4939-9089-4_6  0.652
2018 Ayers KL, Glicksberg BS, Garfield AS, Longerich S, White JA, Yang P, Du L, Chittenden TW, Gulcher JR, Roy S, Fiedorek F, Gottesdiener K, Cohen S, North KE, Schadt EE, ... ... Chen R, et al. Melanocortin-4 receptor pathway dysfunction in obesity: Patient stratification aimed at MC4R agonist treatment. The Journal of Clinical Endocrinology and Metabolism. PMID 29726959 DOI: 10.1210/Jc.2018-00258  0.512
2018 Glicksberg BS, Miotto R, Johnson KW, Shameer K, Li L, Chen R, Dudley JT. Automated disease cohort selection using word embeddings from Electronic Health Records. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 23: 145-156. PMID 29218877  0.654
2018 Smith MR, Glicksberg BS, Li L, Chen R, Morishita H, Dudley JT. Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 23: 68-79. PMID 29218870  0.641
2017 Scott SA, Obeng AO, Botton MR, Yang Y, Scott ER, Ellis SB, Wallsten R, Kaszemacher T, Zhou X, Chen R, Nicoletti P, Naik H, Kenny EE, Vega A, Waite E, et al. Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai. Pharmacogenomics. PMID 28982267 DOI: 10.2217/Pgs-2017-0137  0.531
2017 Pandya C, Uzilov AV, Bellizzi J, Lau CY, Moe AS, Strahl M, Hamou W, Newman LC, Fink MY, Antipin Y, Yu W, Stevenson M, Cavaco BM, Teh BT, Thakker RV, ... ... Chen R, et al. Genomic profiling reveals mutational landscape in parathyroid carcinomas. Jci Insight. 2: e92061. PMID 28352668 DOI: 10.1172/Jci.Insight.92061  0.302
2017 Shameer K, Glicksberg BS, Hodos R, Johnson KW, Badgeley MA, Readhead B, Tomlinson MS, O'Connor T, Miotto R, Kidd BA, Chen R, Ma'ayan A, Dudley JT. Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning. Briefings in Bioinformatics. PMID 28200013 DOI: 10.1093/Bib/Bbw136  0.639
2017 Li L, Greene I, Readhead B, Menon MC, Kidd BA, Uzilov AV, Wei C, Philippe N, Schroppel B, He JC, Chen R, Dudley JT, Murphy B. Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach. Scientific Reports. 7: 39487. PMID 28051114 DOI: 10.1038/Srep39487  0.533
2017 Desnick RJ, Chen R, Srinivasan R, Doheny DO, Bishop D. The Fabry disease genotype-phenotype database (dbFGP): an international expert consortium Molecular Genetics and Metabolism. 120. DOI: 10.1016/J.Ymgme.2016.11.082  0.325
2016 Ma M, Wang C, Glicksberg BS, Schadt EE, Li SD, Chen R. IDENTIFY CANCER DRIVER GENES THROUGH SHARED MENDELIAN DISEASE PATHOGENIC VARIANTS AND CANCER SOMATIC MUTATIONS. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 473-484. PMID 27896999  0.502
2016 Chen B, Solis-Villa C, Hakenberg J, Qiao W, Srinivasan RR, Yasuda M, Balwani M, Doheny D, Peter I, Chen R, Desnick RJ. Acute Intermittent Porphyria: Predicted Pathogenicity of HMBS Variants Indicates Extremely Low Penetrance of the Autosomal Dominant Disease. Human Mutation. PMID 27539938 DOI: 10.1002/Humu.23067  0.325
2016 Ayers KL, Mirshahi UL, Wardeh AH, Murray MF, Hao K, Glicksberg BS, Li S, Carey DJ, Chen R. A loss of function variant in CASP7 protects against Alzheimer's disease in homozygous APOE ε4 allele carriers. Bmc Genomics. 17: 445. PMID 27358062 DOI: 10.1186/S12864-016-2725-Z  0.589
2016 Glicksberg BS, Li L, Badgeley MA, Shameer K, Kosoy R, Beckmann ND, Pho N, Hakenberg J, Ma M, Ayers KL, Hoffman GE, Dan Li S, Schadt EE, Patel CJ, Chen R, et al. Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks. Bioinformatics (Oxford, England). 32: i101-i110. PMID 27307606 DOI: 10.1093/Bioinformatics/Btw282  0.655
2016 Uzilov AV, Ding W, Fink MY, Antipin Y, Brohl AS, Davis C, Lau CY, Pandya C, Shah H, Kasai Y, Powell J, Micchelli M, Castellanos R, Zhang Z, Linderman M, ... ... Chen R, et al. Development and clinical application of an integrative genomic approach to personalized cancer therapy. Genome Medicine. 8: 62. PMID 27245685 DOI: 10.1186/S13073-016-0313-0  0.645
2016 Chen R, Shi L, Hakenberg J, Naughton B, Sklar P, Zhang J, Zhou H, Tian L, Prakash O, Lemire M, Sleiman P, Cheng WY, Chen W, Shah H, Shen Y, et al. Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases. Nature Biotechnology. PMID 27065010 DOI: 10.1038/Nbt.3514  0.373
2016 Hakenberg J, Cheng WY, Thomas P, Wang YC, Uzilov AV, Chen R. Integrating 400 million variants from 80,000 human samples with extensive annotations: towards a knowledge base to analyze disease cohorts. Bmc Bioinformatics. 17: 24. PMID 26746786 DOI: 10.1186/S12859-015-0865-9  0.378
2015 Shoemaker LD, Clark MJ, Patwardhan A, Chandratillake G, Garcia S, Chen R, Morgan AA, Leng N, Kirk S, Chen R, Cook DJ, Snyder M, Steinberg GK. Disease Variant Landscape of a Large Multi-ethnic Population of Moyamoya Patients by Exome Sequencing. G3 (Bethesda, Md.). PMID 26530418 DOI: 10.1534/G3.115.020321  0.309
2015 Li L, Cheng WY, Glicksberg BS, Gottesman O, Tamler R, Chen R, Bottinger EP, Dudley JT. Identification of type 2 diabetes subgroups through topological analysis of patient similarity. Science Translational Medicine. 7: 311ra174. PMID 26511511 DOI: 10.1126/Scitranslmed.Aaa9364  0.688
2015 Cheng WY, Hakenberg J, Li SD, Chen R. DIVAS: a centralized genetic variant repository representing 150 000 individuals from multiple disease cohorts. Bioinformatics (Oxford, England). PMID 26363178 DOI: 10.1093/Bioinformatics/Btv511  0.342
2015 Wang J, Liao J, Zhang J, Cheng WY, Hakenberg J, Ma M, Webb BD, Ramasamudram-Chakravarthi R, Karger L, Mehta L, Kornreich R, Diaz GA, Li S, Edelmann L, Chen R. ClinLabGeneticist: a tool for clinical management of genetic variants from whole exome sequencing in clinical genetic laboratories. Genome Medicine. 7: 77. PMID 26338694 DOI: 10.1186/S13073-015-0207-6  0.339
2015 Hao K, Di Narzo AF, Ho L, Luo W, Li S, Chen R, Li T, Dubner L, Pasinetti GM. Shared genetic etiology underlying alzheimer's Disease and type 2 Diabetes. Molecular Aspects of Medicine. PMID 26116273 DOI: 10.1016/J.Mam.2015.06.006  0.316
2015 Ma M, Ru Y, Chuang LS, Hsu NY, Shi LS, Hakenberg J, Cheng WY, Uzilov A, Ding W, Glicksberg BS, Chen R. Disease-associated variants in different categories of disease located in distinct regulatory elements. Bmc Genomics. 16: S3. PMID 26110593 DOI: 10.1186/1471-2164-16-S8-S3  0.622
2015 Glicksberg BS, Li L, Cheng WY, Shameer K, Hakenberg J, Castellanos R, Ma M, Shi L, Shah H, Dudley JT, Chen R. An integrative pipeline for multi-modal discovery of disease relationships. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 407-18. PMID 25592600  0.672
2014 Li L, Ruau DJ, Patel CJ, Weber SC, Chen R, Tatonetti NP, Dudley JT, Butte AJ. Disease risk factors identified through shared genetic architecture and electronic medical records. Science Translational Medicine. 6: 234ra57. PMID 24786325 DOI: 10.1126/Scitranslmed.3007191  0.675
2014 Enns GM, Shashi V, Bainbridge M, Gambello MJ, Zahir FR, Bast T, Crimian R, Schoch K, Platt J, Cox R, Bernstein JA, Scavina M, Walter RS, Bibb A, Jones M, ... ... Chen R, et al. Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 16: 751-8. PMID 24651605 DOI: 10.1038/Gim.2014.22  0.473
2014 Li L, Readhead B, Chen R, Zhang W, Murphy B, Dudley J. An Integrative Informatics Approach to Identify Drug Targets and Therapies for Chronic Allograft Nephropathy After Kidney Transplantation.: Abstract# 2928 Transplantation. 98: 230. DOI: 10.1097/00007890-201407151-00683  0.502
2013 Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. Systematic identification of interaction effects between validated genome- and environment-wide associations on Type 2 Diabetes Mellitus. Amia Joint Summits On Translational Science Proceedings Amia Summit On Translational Science. 2013: 135. PMID 24303322  0.433
2013 Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, Chen R, Morgan AA, Martin GS, Brigham KL, Butte AJ, Gibson G. Whole genome sequencing in support of wellness and health maintenance. Genome Medicine. 5: 58. PMID 23806097 DOI: 10.1186/Gm462  0.549
2013 Hsu I, Chen R, Ramesh A, Corona E, Kang HP, Ruau D, Butte AJ. Systematic identification of DNA variants associated with ultraviolet radiation using a novel Geographic-Wide Association Study (GeoWAS). Bmc Medical Genetics. 14: 62. PMID 23786662 DOI: 10.1186/1471-2350-14-62  0.519
2013 Corona E, Chen R, Sikora M, Morgan AA, Patel CJ, Ramesh A, Bustamante CD, Butte AJ. Analysis of the genetic basis of disease in the context of worldwide human relationships and migration. Plos Genetics. 9: e1003447. PMID 23717210 DOI: 10.1371/Journal.Pgen.1003447  0.524
2013 Karczewski KJ, Dudley JT, Kukurba KR, Chen R, Butte AJ, Montgomery SB, Snyder M. Systematic functional regulatory assessment of disease-associated variants. Proceedings of the National Academy of Sciences of the United States of America. 110: 9607-12. PMID 23690573 DOI: 10.1073/Pnas.1219099110  0.68
2013 Sigdel TK, Shoemaker LD, Chen R, Li L, Butte AJ, Sarwal MM, Steinberg GK. Immune response profiling identifies autoantibodies specific to Moyamoya patients. Orphanet Journal of Rare Diseases. 8: 45. PMID 23518061 DOI: 10.1186/1750-1172-8-45  0.544
2013 Li L, Ruau D, Chen R, Weber S, Butte AJ. Systematic identification of risk factors for Alzheimer's disease through shared genetic architecture and electronic medical records. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 224-35. PMID 23424127  0.42
2013 Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. Human Genetics. 132: 495-508. PMID 23334806 DOI: 10.1007/S00439-012-1258-Z  0.544
2012 Kidd JM, Gravel S, Byrnes J, Moreno-Estrada A, Musharoff S, Bryc K, Degenhardt JD, Brisbin A, Sheth V, Chen R, McLaughlin SF, Peckham HE, Omberg L, Bormann Chung CA, Stanley S, et al. Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. American Journal of Human Genetics. 91: 660-71. PMID 23040495 DOI: 10.1016/J.Ajhg.2012.08.025  0.533
2012 Li L, Khatri P, Sigdel TK, Tran T, Ying L, Vitalone MJ, Chen A, Hsieh S, Dai H, Zhang M, Naesens M, Zarkhin V, Sansanwal P, Chen R, Mindrinos M, et al. A peripheral blood diagnostic test for acute rejection in renal transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 2710-8. PMID 23009139 DOI: 10.1111/J.1600-6143.2012.04253.X  0.498
2012 Gupta R, Ratan A, Rajesh C, Chen R, Kim HL, Burhans R, Miller W, Santhosh S, Davuluri RV, Butte AJ, Schuster SC, Seshagiri S, Thomas G. Sequencing and analysis of a South Asian-Indian personal genome. Bmc Genomics. 13: 440. PMID 22938532 DOI: 10.1186/1471-2164-13-440  0.556
2012 Kang HP, Morgan AA, Chen R, Schadt EE, Butte AJ. Coanalysis of GWAS with eQTLs reveals disease-tissue associations. Amia Joint Summits On Translational Science Proceedings Amia Summit On Translational Science. 2012: 35-41. PMID 22779046  0.48
2012 Chen R, Dudley JT, Ruau D, Butte AJ. Quantifying multi-ethnic representation in genetic studies of high mortality diseases. Amia Joint Summits On Translational Science Proceedings Amia Summit On Translational Science. 2012: 11-8. PMID 22779041  0.631
2012 Morgan AA, Chen R, Butte AJ. Clinical utility of sequence-based genotype compared with that derivable from genotyping arrays. Journal of the American Medical Informatics Association : Jamia. 19: e21-7. PMID 22718036 DOI: 10.1136/Amiajnl-2011-000737  0.505
2012 Patel CJ, Chen R, Butte AJ. Data-driven integration of epidemiological and toxicological data to select candidate interacting genes and environmental factors in association with disease. Bioinformatics (Oxford, England). 28: i121-6. PMID 22689751 DOI: 10.1093/Bioinformatics/Bts229  0.544
2012 Ruau D, Dudley JT, Chen R, Phillips NG, Swan GE, Lazzeroni LC, Clark JD, Butte AJ, Angst MS. Integrative approach to pain genetics identifies pain sensitivity loci across diseases. Plos Computational Biology. 8: e1002538. PMID 22685391 DOI: 10.1371/Journal.Pcbi.1002538  0.634
2012 Dudley JT, Kim Y, Liu L, Markov GJ, Gerold K, Chen R, Butte AJ, Kumar S. Human genomic disease variants: a neutral evolutionary explanation. Genome Research. 22: 1383-94. PMID 22665443 DOI: 10.1101/Gr.133702.111  0.671
2012 Chen R, Corona E, Sikora M, Dudley JT, Morgan AA, Moreno-Estrada A, Nilsen GB, Ruau D, Lincoln SE, Bustamante CD, Butte AJ. Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases. Plos Genetics. 8: e1002621. PMID 22511877 DOI: 10.1371/Journal.Pgen.1002621  0.634
2012 Kodama K, Horikoshi M, Toda K, Yamada S, Hara K, Irie J, Sirota M, Morgan AA, Chen R, Ohtsu H, Maeda S, Kadowaki T, Butte AJ. Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 109: 7049-54. PMID 22499789 DOI: 10.1073/Pnas.1114513109  0.503
2012 Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 148: 1293-307. PMID 22424236 DOI: 10.1016/J.Cell.2012.02.009  0.66
2012 Dudley JT, Chen R, Sanderford M, Butte AJ, Kumar S. Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery. Molecular Biology and Evolution. 29: 2087-94. PMID 22389448 DOI: 10.1093/Molbev/Mss079  0.681
2012 Lam HY, Clark MJ, Chen R, Chen R, Natsoulis G, O'Huallachain M, Dewey FE, Habegger L, Ashley EA, Gerstein MB, Butte AJ, Ji HP, Snyder M. Performance comparison of whole-genome sequencing platforms. Nature Biotechnology. 30: 78-82. PMID 22178993 DOI: 10.1038/Nbt.2065  0.535
2012 Lam HYK, Clark MJ, Chen R, Chen R, Natsoulis G, O'Huallachain M, Dewey FE, Habegger L, Ashley EA, Gerstein MB, Butte AJ, Ji HP, Snyder M. Erratum: Corrigendum: Performance comparison of whole-genome sequencing platforms Nature Biotechnology. 30: 562-562. DOI: 10.1038/Nbt0612-562E  0.473
2011 Engreitz JM, Chen R, Morgan AA, Dudley JT, Mallelwar R, Butte AJ. ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression. Bioinformatics (Oxford, England). 27: 3317-8. PMID 21967760 DOI: 10.1093/Bioinformatics/Btr548  0.646
2011 Clark MJ, Chen R, Lam HY, Karczewski KJ, Chen R, Euskirchen G, Butte AJ, Snyder M. Performance comparison of exome DNA sequencing technologies. Nature Biotechnology. 29: 908-14. PMID 21947028 DOI: 10.1038/Nbt.1975  0.508
2011 Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, et al. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. Plos Genetics. 7: e1002280. PMID 21935354 DOI: 10.1371/Journal.Pgen.1002280  0.658
2011 Naesens M, Khatri P, Li L, Sigdel TK, Vitalone MJ, Chen R, Butte AJ, Salvatierra O, Sarwal MM. Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes. Kidney International. 80: 1364-76. PMID 21881554 DOI: 10.1038/Ki.2011.245  0.488
2011 Dudley JT, Chen R, Butte AJ. Matching cancer genomes to established cell lines for personalized oncology. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 243-52. PMID 21121052  0.607
2011 Chen R, Butte AJ. The reference human genome demonstrates high risk of type 1 diabetes and other disorders. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 231-42. PMID 21121051  0.505
2010 Engreitz JM, Morgan AA, Dudley JT, Chen R, Thathoo R, Altman RB, Butte AJ. Content-based microarray search using differential expression profiles. Bmc Bioinformatics. 11: 603. PMID 21172034 DOI: 10.1186/1471-2105-11-603  0.642
2010 Chen R, Davydov EV, Sirota M, Butte AJ. Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association. Plos One. 5: e13574. PMID 21042586 DOI: 10.1371/Journal.Pone.0013574  0.536
2010 Chen R, Sigdel TK, Li L, Kambham N, Dudley JT, Hsieh SC, Klassen RB, Chen A, Caohuu T, Morgan AA, Valantine HA, Khush KK, Sarwal MM, Butte AJ. Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions. Plos Computational Biology. 6. PMID 20885780 DOI: 10.1371/Journal.Pcbi.1000940  0.644
2010 Dudley JT, Pouliot Y, Chen R, Morgan AA, Butte AJ. Translational bioinformatics in the cloud: an affordable alternative. Genome Medicine. 2: 51. PMID 20691073 DOI: 10.1186/Gm172  0.633
2010 Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ, Su Z, Chu TM, Goodsaid FM, Pusztai L, Shaughnessy JD, Oberthuer A, Thomas RS, Paules RS, Fielden M, ... ... Chen R, et al. The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nature Biotechnology. 28: 827-38. PMID 20676074 DOI: 10.1038/Nbt.1665  0.304
2010 Morgan AA, Chen R, Butte AJ. Likelihood ratios for genome medicine. Genome Medicine. 2: 30. PMID 20497613 DOI: 10.1186/Gm151  0.558
2010 Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, et al. Clinical assessment incorporating a personal genome. Lancet (London, England). 375: 1525-35. PMID 20435227 DOI: 10.1016/S0140-6736(10)60452-7  0.646
2010 Suthram S, Dudley JT, Chiang AP, Chen R, Hastie TJ, Butte AJ. Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets. Plos Computational Biology. 6: e1000662. PMID 20140234 DOI: 10.1371/Journal.Pcbi.1000662  0.664
2010 Morgan AA, Chen R, Butte AJ, Ashley EA. Clinical assessment incorporating a personal genome – Authors' reply The Lancet. 376: 869-870. DOI: 10.1016/S0140-6736(10)61405-5  0.498
2009 Li L, Wadia P, Chen R, Kambham N, Naesens M, Sigdel TK, Miklos DB, Sarwal MM, Butte AJ. Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures. Proceedings of the National Academy of Sciences of the United States of America. 106: 4148-53. PMID 19251643 DOI: 10.1073/Pnas.0900563106  0.488
2009 Shah NH, Jonquet C, Chiang AP, Butte AJ, Chen R, Musen MA. Ontology-driven indexing of public datasets for translational bioinformatics. Bmc Bioinformatics. 10: S1. PMID 19208184 DOI: 10.1186/1471-2105-10-S2-S1  0.535
2008 Chen R, Mallelwar R, Thosar A, Venkatasubrahmanyam S, Butte AJ. GeneChaser: identifying all biological and clinical conditions in which genes of interest are differentially expressed. Bmc Bioinformatics. 9: 548. PMID 19094235 DOI: 10.1186/1471-2105-9-548  0.522
2008 Chen R, Morgan AA, Dudley J, Deshpande T, Li L, Kodama K, Chiang AP, Butte AJ. FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease. Genome Biology. 9: R170. PMID 19061490 DOI: 10.1186/Gb-2008-9-12-R170  0.627
2008 Chen R, Li L, Butte AJ. AILUN: reannotating gene expression data automatically. Nature Methods. 4: 879. PMID 17971777 DOI: 10.1038/Nmeth1107-879  0.482
2008 Sarwal M, Li L, Wadia P, Chen R, Naesens M, Miklos D, Butte A. INTEGRATIVE GENOMICS TO IDENTIFY NON-HLA ALLOGENIC KIDNEY-SPECIFIC TARGETS AFTER KIDNEY TRANSPLANTATION Transplantation. 86: 13. DOI: 10.1097/01.Tp.0000332715.73087.A0  0.494
2007 Lin YA, Chiang A, Lin R, Yao P, Chen R, Butte AJ. Methodologies for extracting functional pharmacogenomic experiments from international repository. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 463-7. PMID 18693879  0.456
2007 Mintseris J, Pierce B, Wiehe K, Anderson R, Chen R, Weng Z. Integrating statistical pair potentials into protein complex prediction. Proteins. 69: 511-20. PMID 17623839 DOI: 10.1002/Prot.21502  0.758
2007 Butte AJ, Chen R. Finding disease-related genomic experiments within an international repository: first steps in translational bioinformatics. Amia ... Annual Symposium Proceedings. Amia Symposium. 106-10. PMID 17238312  0.497
2005 Mintseris J, Wiehe K, Pierce B, Anderson R, Chen R, Janin J, Weng Z. Protein-Protein Docking Benchmark 2.0: an update. Proteins. 60: 214-6. PMID 15981264 DOI: 10.1002/Prot.20560  0.753
2005 Wiehe K, Pierce B, Mintseris J, Tong WW, Anderson R, Chen R, Weng Z. ZDOCK and RDOCK performance in CAPRI rounds 3, 4, and 5. Proteins. 60: 207-13. PMID 15981263 DOI: 10.1002/Prot.20559  0.752
2003 Li L, Chen R, Weng Z. RDOCK: refinement of rigid-body protein docking predictions. Proteins. 53: 693-707. PMID 14579360 DOI: 10.1002/Prot.10460  0.507
2003 Chen R, Mintseris J, Janin J, Weng Z. A protein-protein docking benchmark. Proteins. 52: 88-91. PMID 12784372 DOI: 10.1002/Prot.10390  0.729
2003 Chen R, Li L, Weng Z. ZDOCK: an initial-stage protein-docking algorithm. Proteins. 52: 80-7. PMID 12784371 DOI: 10.1002/Prot.10389  0.523
2003 Chen R, Tong W, Mintseris J, Li L, Weng Z. ZDOCK predictions for the CAPRI challenge. Proteins. 52: 68-73. PMID 12784369 DOI: 10.1002/Prot.10388  0.756
2003 Chen R, Weng Z. A novel shape complementarity scoring function for protein-protein docking. Proteins. 51: 397-408. PMID 12696051 DOI: 10.1002/Prot.10334  0.524
2002 Chen R, Weng Z. Docking unbound proteins using shape complementarity, desolvation, and electrostatics. Proteins. 47: 281-94. PMID 11948782 DOI: 10.1002/Prot.10092  0.505
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