Heping (Peace) Cheng - Publications

Affiliations: 
Institute of Molecular Medicine Peking University, Beijing, Beijing Shi, China 

156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lu F, Li Y, Lin S, Cheng H, Yang S. Spatiotemporal regulation of store-operated calcium entry in cancer metastasis. Biochemical Society Transactions. PMID 34854917 DOI: 10.1042/BST20210307  0.306
2020 Lu F, Zhao Y, Xie W, Guo Q, Wang SQ, Wang X, Cheng H. Imaging Sarcoplasmic Reticulum Ca Signaling in Intact Cardiac Myocytes. Circulation. 142: 1503-1505. PMID 33044861 DOI: 10.1161/CIRCULATIONAHA.120.047784  0.352
2020 Wu D, Jian C, Peng Q, Hou T, Wu K, Shang B, Zhao M, Wang Y, Zheng W, Ma Q, Li CY, Cheng H, Wang X, Zhao L. Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure. Cell Death & Disease. 11: 181. PMID 32165613 DOI: 10.1038/S41419-020-2374-7  0.314
2019 Lin Y, Li LL, Nie W, Liu X, Adler A, Xiao C, Lu F, Wang L, Han H, Wang X, Gan WB, Cheng H. Brain activity regulates loose coupling between mitochondrial and cytosolic Ca transients. Nature Communications. 10: 5277. PMID 31754099 DOI: 10.1038/S41467-019-13142-0  0.681
2019 Hou T, Zhang R, Jian C, Ding W, Wang Y, Ling S, Ma Q, Hu X, Cheng H, Wang X. NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly. Cell Research. PMID 31366990 DOI: 10.1038/S41422-019-0208-X  0.337
2019 Sun C, Shui B, Zhao W, Liu H, Li W, Lee JC, Doran R, Lee FK, Sun T, Shen QS, Wang X, Reining S, Kotlikoff MI, Zhang Z, Cheng H. Central role of IPR2-mediated Ca oscillation in self-renewal of liver cancer stem cells elucidated by high-signal ER sensor. Cell Death & Disease. 10: 396. PMID 31113961 DOI: 10.1038/S41419-019-1613-2  0.443
2019 Li S, Keung W, Cheng H, Li RA. Structural and Mechanistic Bases of Nuclear Calcium Signaling in Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes. Stem Cells International. 2019: 8765752. PMID 31065282 DOI: 10.1155/2019/8765752  0.393
2019 Lu F, Sun J, Zheng Q, Li J, Hu Y, Yu P, He H, Zhao Y, Wang X, Yang S, Cheng H. Imaging elemental events of store-operated Ca entry in invading cancer cells with plasmalemmal targeted sensors. Journal of Cell Science. PMID 30814332 DOI: 10.1242/Jcs.224923  0.487
2018 Zhao Q, Lu D, Wang J, Liu B, Cheng H, Mattson MP, Cheng A. Calcium dysregulation mediates mitochondrial and neurite outgrowth abnormalities in SOD2 deficient embryonic cerebral cortical neurons. Cell Death and Differentiation. PMID 30390091 DOI: 10.1038/S41418-018-0230-4  0.393
2018 Ye J, Zheng Q, Jia S, Qiao X, Cao Y, Xu C, Weng L, Zhao L, Chen Y, Liu J, Wang T, Cheng H, Zheng M. Programmed Cell Death 5 Provides Negative Feedback on Cardiac Hypertrophy Through the Stabilization of Sarco/Endoplasmic Reticulum Ca-ATPase 2a Protein. Hypertension (Dallas, Tex. : 1979). 72: 889-901. PMID 30354711 DOI: 10.1161/Hypertensionaha.118.11357  0.414
2018 Lu F, Sun J, Sun T, Cheng H, Yang S. Fluorescence-Based Measurements of Store-Operated Ca Entry in Cancer Cells Using Fluo-4 and Confocal Live-Cell Imaging. Methods in Molecular Biology (Clifton, N.J.). 1843: 63-68. PMID 30203277 DOI: 10.1007/978-1-4939-8704-7_5  0.309
2017 Wang X, Zhang X, Wu D, Huang Z, Hou T, Jian C, Yu P, Lu F, Zhang R, Sun T, Li J, Qi W, Wang Y, Gao F, Cheng H. Mitochondrial flashes regulate ATP homeostasis in the heart. Elife. 6. PMID 28692422 DOI: 10.7554/Elife.23908  0.336
2017 Fu ZX, Tan X, Fang H, Lau PM, Wang X, Cheng H, Bi GQ. Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity. Nature Communications. 8: 31. PMID 28652625 DOI: 10.1038/S41467-017-00043-3  0.307
2017 Jian C, Xu F, Hou T, Sun T, Jinghang L, Cheng H, Wang X. Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes. Journal of Cell Science. PMID 28630166 DOI: 10.1242/Jcs.198523  0.333
2017 Karam C, Yi J, Xiao Y, Dhakal K, Zhang L, Li X, Manno C, Xu J, Li K, Cheng H, Ma J, Zhou J. Absence of physiological Ca(2+) transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation. Skeletal Muscle. 7: 6. PMID 28395670 DOI: 10.1186/S13395-017-0123-0  0.361
2017 Feng G, Liu B, Hou T, Wang X, Cheng H. Mitochondrial Flashes: Elemental Signaling Events in Eukaryotic Cells. Handbook of Experimental Pharmacology. PMID 28233181 DOI: 10.1007/164_2016_129  0.374
2017 Wang X, Zhang X, Wu D, Huang Z, Hou T, Jian C, Yu P, Lu F, Zhang R, Sun T, Li J, Qi W, Wang Y, Gao F, Cheng H. Author response: Mitochondrial flashes regulate ATP homeostasis in the heart Elife. DOI: 10.7554/Elife.23908.024  0.332
2017 Li J, Xie W, Chen X, Huo Y, Cheng H, Tan W. A novel stochastic reaction-diffusion model of Ca 2+ blink in cardiac myocytes Science Bulletin. 62: 5-8. DOI: 10.1016/J.Scib.2016.12.001  0.397
2016 Li W, Sun T, Liu B, Wu D, Qi W, Wang X, Ma Q, Cheng H. Regulation of Mitoflash Biogenesis and Signaling by Mitochondrial Dynamics. Scientific Reports. 6: 32933. PMID 27623243 DOI: 10.1038/Srep32933  0.306
2016 Wang X, Zhang X, Huang Z, Wu D, Liu B, Zhang R, Yin R, Hou T, Jian C, Xu J, Zhao Y, Wang Y, Gao F, Cheng H. Protons Trigger Mitochondrial Flashes. Biophysical Journal. 111: 386-394. PMID 27463140 DOI: 10.1016/J.Bpj.2016.05.052  0.337
2016 Wang W, Zhang H, Cheng H. Mitochondrial flashes: from indicator characterization to in vivo imaging. Methods (San Diego, Calif.). PMID 27288722 DOI: 10.1016/J.Ymeth.2016.06.004  0.352
2016 Wang W, Gong G, Wang X, Wei-LaPierre L, Cheng H, Dirksen RT, Sheu SS. Mitochondrial Flash: Integrative ROS and pH Signals in Cell and Organelle Biology. Antioxidants & Redox Signaling. PMID 27245241 DOI: 10.1089/Ars.2016.6739  0.324
2016 Hou T, Jian C, Xu J, Huang AY, Xi J, Hu K, Wei L, Cheng H, Wang X. Identification of EFHD1 as a novel Ca(2+) sensor for mitoflash activation. Cell Calcium. PMID 26975899 DOI: 10.1016/J.Ceca.2016.03.002  0.482
2016 Karam C, Yi J, Manno C, Cheng H, Ma J, Zhou J. Absence of Physiological Calcium Transients Triggers Mitochondrial ROS Production in Skeletal Muscle Following Denervation Biophysical Journal. 110: 311a. DOI: 10.1016/J.Bpj.2015.11.1669  0.421
2015 Shang W, Gao H, Lu F, Ma Q, Fang H, Sun T, Xu J, Ding Y, Lin Y, Wang Y, Wang X, Cheng H, Zheng M. Cyclophilin D regulates mitochondrial flashes and metabolism in cardiac myocytes. Journal of Molecular and Cellular Cardiology. PMID 26746144 DOI: 10.1016/J.Yjmcc.2015.10.036  0.456
2015 Zhang M, Sun T, Jian C, Lei L, Han P, Lv Q, Yang R, Zhou X, Xu J, Hu Y, Men Y, Huang Y, Zhang C, Zhu X, Wang X, ... Cheng H, et al. Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish. Plos One. 10: e0132567. PMID 26186000 DOI: 10.1371/Journal.Pone.0132567  0.326
2015 Ding Y, Fang H, Shang W, Xiao Y, Sun T, Hou N, Pan L, Sun X, Ma Q, Zhou J, Wang X, Zhang X, Cheng H. Mitoflash altered by metabolic stress in insulin-resistant skeletal muscle. Journal of Molecular Medicine (Berlin, Germany). PMID 25908643 DOI: 10.1007/S00109-015-1278-Y  0.323
2015 Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L. Large-field high-resolution two-photon digital scanned light-sheet microscopy. Cell Research. 25: 254-7. PMID 25257466 DOI: 10.1038/Cr.2014.124  0.352
2015 Brochet DX, Wang G, Lederer WJ, Cheng H. Calcium Signaling among RyR2s within a Calcium Release Unit during a Calcium Spark Biophysical Journal. 108: 568a. DOI: 10.1016/J.Bpj.2014.11.3108  0.502
2014 Sun J, Lu F, He H, Shen J, Messina J, Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, Cheng H, Yang S. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion. The Journal of Cell Biology. 207: 535-48. PMID 25404747 DOI: 10.1083/Jcb.201407082  0.418
2014 Han P, Zhou XH, Chang N, Xiao CL, Yan S, Ren H, Yang XZ, Zhang ML, Wu Q, Tang B, Diao JP, Zhu X, Zhang C, Li CY, Cheng H, et al. Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Research. 24: 1091-107. PMID 25124925 DOI: 10.1038/Cr.2014.108  0.316
2014 Hou T, Wang X, Ma Q, Cheng H. Mitochondrial flashes: new insights into mitochondrial ROS signalling and beyond. The Journal of Physiology. 592: 3703-13. PMID 25038239 DOI: 10.1113/Jphysiol.2014.275735  0.343
2014 Zhang W, Li K, Zhu X, Wu D, Shang W, Yuan X, Huang Z, Zheng M, Wang X, Yang D, Liu J, Cheng H. Subsarcolemmal mitochondrial flashes induced by hypochlorite stimulation in cardiac myocytes. Free Radical Research. 48: 1085-94. PMID 24912881 DOI: 10.3109/10715762.2014.932114  0.448
2014 Yan W, Zhang F, Zhang R, Zhang X, Wang Y, Zhou F, Xia Y, Liu P, Gao C, Wang H, Zhang L, Zhou J, Gao F, Gao E, Koch WJ, ... ... Cheng H, et al. Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. Journal of Molecular and Cellular Cardiology. 74: 183-92. PMID 24852843 DOI: 10.1016/J.Yjmcc.2014.05.010  0.468
2014 Jian C, Hou T, Yin R, Cheng H, Wang X. Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations. Science China. Life Sciences. 57: 495-501. PMID 24699914 DOI: 10.1007/S11427-014-4628-Z  0.354
2014 Shen EZ, Song CQ, Lin Y, Zhang WH, Su PF, Liu WY, Zhang P, Xu J, Lin N, Zhan C, Wang X, Shyr Y, Cheng H, Dong MQ. Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans. Nature. 508: 128-32. PMID 24522532 DOI: 10.1038/Nature13012  0.401
2014 Hou Y, Ghosh P, Wan R, Ouyang X, Cheng H, Mattson MP, Cheng A. Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1-42 on neural progenitor cell proliferation. Neurobiology of Aging. 35: 975-89. PMID 24325797 DOI: 10.1016/J.Neurobiolaging.2013.11.002  0.338
2014 Shang W, Lu F, Sun T, Xu J, Li LL, Wang Y, Wang G, Chen L, Wang X, Cannell MB, Wang SQ, Cheng H. Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Circulation Research. 114: 412-20. PMID 24257462 DOI: 10.1161/Circresaha.114.302938  0.489
2014 Li S, Cheng H, Tomaselli GF, Li RA. Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: direct evidence of functional Ca2+-induced Ca2+ release. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 133-40. PMID 24096168 DOI: 10.1016/j.hrthm.2013.10.006  0.365
2014 Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L. Two-photon three-axis digital scanned light-sheet microscopy (2P3A-DSLM) Proceedings of Spie. 9198. DOI: 10.1117/12.2062690  0.374
2014 Shang W, Lu F, Sun T, Xu J, Li L, Wang Y, Chen L, Wang X, Cannell MB, Wang S, Cheng H. Ca2+ Nanosparks: Junctional Ca2+ Dynamics Probed with a New Targeted Biosensor Biophysical Journal. 106: 319a-320a. DOI: 10.1016/J.Bpj.2013.11.1845  0.498
2014 Cheng H, Wang X, Ma Q, Wang W. Origin and Mechanism of Mitochondrial Flashes Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1286  0.355
2013 Zhang H, Shang W, Zhang X, Gu J, Wang X, Zheng M, Wang Y, Zhou Z, Cao JM, Ji G, Zhang R, Cheng H. Β-adrenergic-stimulated L-type channel Ca²+ entry mediates hypoxic Ca²+ overload in intact heart. Journal of Molecular and Cellular Cardiology. 65: 51-8. PMID 24041537 DOI: 10.1016/J.Yjmcc.2013.09.002  0.508
2013 Wang X, Fang H, Huang Z, Shang W, Hou T, Cheng A, Cheng H. Imaging ROS signaling in cells and animals. Journal of Molecular Medicine (Berlin, Germany). 91: 917-27. PMID 23873151 DOI: 10.1007/S00109-013-1067-4  0.321
2013 Cao Y, Zhang X, Shang W, Xu J, Wang X, Hu X, Ao Y, Cheng H. Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ. Plos One. 8: e66444. PMID 23840469 DOI: 10.1371/Journal.Pone.0066444  0.31
2013 Zhang X, Huang Z, Hou T, Xu J, Wang Y, Shang W, Ye T, Cheng H, Gao F, Wang X. Superoxide constitutes a major signal of mitochondrial superoxide flash. Life Sciences. 93: 178-86. PMID 23800644 DOI: 10.1016/J.Lfs.2013.06.012  0.324
2013 Sipido KR, Cheng H. T-tubules and ryanodine receptor microdomains: on the road to translation. Cardiovascular Research. 98: 159-61. PMID 23554456 DOI: 10.1093/Cvr/Cvt077  0.457
2013 Wei-LaPierre L, Gong G, Gerstner BJ, Ducreux S, Yule DI, Pouvreau S, Wang X, Sheu SS, Cheng H, Dirksen RT, Wang W. Respective contribution of mitochondrial superoxide and pH to mitochondria-targeted circularly permuted yellow fluorescent protein (mt-cpYFP) flash activity. The Journal of Biological Chemistry. 288: 10567-77. PMID 23457298 DOI: 10.1074/Jbc.M113.455709  0.312
2013 Zhang H, Gomez AM, Wang X, Yan Y, Zheng M, Cheng H. ROS regulation of microdomain Ca(2+) signalling at the dyads. Cardiovascular Research. 98: 248-58. PMID 23455546 DOI: 10.1093/Cvr/Cvt050  0.472
2013 Liu Y, Cheng H, Zhou Y, Zhu Y, Bian R, Chen Y, Li C, Ma Q, Zheng Q, Zhang Y, Jin H, Wang X, Chen Q, Zhu D. Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells. Cell Death & Disease. 4: e494. PMID 23412387 DOI: 10.1038/Cddis.2013.31  0.311
2013 Huang X, Sun L, Ji S, Zhao T, Zhang W, Xu J, Zhang J, Wang Y, Wang X, Franzini-Armstrong C, Zheng M, Cheng H. Kissing and nanotunneling mediate intermitochondrial communication in the heart. Proceedings of the National Academy of Sciences of the United States of America. 110: 2846-51. PMID 23386722 DOI: 10.1073/Pnas.1300741110  0.331
2013 Pereira L, Cheng H, Lao DH, Na L, van Oort RJ, Brown JH, Wehrens XH, Chen J, Bers DM. Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia. Circulation. 127: 913-22. PMID 23363625 DOI: 10.1161/Circulationaha.12.148619  0.472
2013 Hou T, Zhang X, Xu J, Jian C, Huang Z, Ye T, Hu K, Zheng M, Gao F, Wang X, Cheng H. Synergistic triggering of superoxide flashes by mitochondrial Ca2+ uniport and basal reactive oxygen species elevation. The Journal of Biological Chemistry. 288: 4602-12. PMID 23283965 DOI: 10.1074/Jbc.M112.398297  0.477
2012 Hou Y, Ouyang X, Wan R, Cheng H, Mattson MP, Cheng A. Mitochondrial superoxide production negatively regulates neural progenitor proliferation and cerebral cortical development. Stem Cells (Dayton, Ohio). 30: 2535-47. PMID 22949407 DOI: 10.1002/Stem.1213  0.33
2012 Zhao T, Huang X, Han L, Wang X, Cheng H, Zhao Y, Chen Q, Chen J, Cheng H, Xiao R, Zheng M. Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. The Journal of Biological Chemistry. 287: 23615-25. PMID 22619176 DOI: 10.1074/Jbc.M112.379164  0.359
2012 Brochet DX, Yang D, Cheng H, Lederer WJ. Elementary calcium release events from the sarcoplasmic reticulum in the heart. Advances in Experimental Medicine and Biology. 740: 499-509. PMID 22453956 DOI: 10.1007/978-94-007-2888-2_21  0.486
2012 Wang X, Jian C, Zhang X, Huang Z, Xu J, Hou T, Shang W, Ding Y, Zhang W, Ouyang M, Wang Y, Yang Z, Zheng M, Cheng H. Superoxide flashes: elemental events of mitochondrial ROS signaling in the heart. Journal of Molecular and Cellular Cardiology. 52: 940-8. PMID 22405973 DOI: 10.1016/J.Yjmcc.2012.02.007  0.375
2012 Li K, Zhang W, Fang H, Xie W, Liu J, Zheng M, Wang X, Wang W, Tan W, Cheng H. Superoxide flashes reveal novel properties of mitochondrial reactive oxygen species excitability in cardiomyocytes. Biophysical Journal. 102: 1011-21. PMID 22404923 DOI: 10.1016/J.Bpj.2012.01.044  0.339
2011 Zhou Q, Xiao J, Jiang D, Wang R, Vembaiyan K, Wang A, Smith CD, Xie C, Chen W, Zhang J, Tian X, Jones PP, Zhong X, Guo A, Chen H, ... ... Cheng H, et al. Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nature Medicine. 17: 1003-9. PMID 21743453 DOI: 10.1038/Nm.2406  0.381
2011 Han P, Cai W, Wang Y, Lam CK, Arvanitis DA, Singh VP, Chen S, Zhang H, Zhang R, Cheng H, Kranias EG. Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1588-95. PMID 21742996 DOI: 10.1152/Ajpheart.01153.2010  0.473
2011 Ma Q, Fang H, Shang W, Liu L, Xu Z, Ye T, Wang X, Zheng M, Chen Q, Cheng H. Superoxide flashes: early mitochondrial signals for oxidative stress-induced apoptosis. The Journal of Biological Chemistry. 286: 27573-81. PMID 21659534 DOI: 10.1074/Jbc.M111.241794  0.342
2011 Fang H, Chen M, Ding Y, Shang W, Xu J, Zhang X, Zhang W, Li K, Xiao Y, Gao F, Shang S, Li JC, Tian XL, Wang SQ, Zhou J, ... ... Cheng H, et al. Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals. Cell Research. 21: 1295-304. PMID 21556035 DOI: 10.1038/Cr.2011.81  0.348
2011 Lin N, Badie N, Yu L, Abraham D, Cheng H, Bursac N, Rockman HA, Wolf MJ. A method to measure myocardial calcium handling in adult Drosophila. Circulation Research. 108: 1306-15. PMID 21493892 DOI: 10.1161/Circresaha.110.238105  0.501
2011 Brochet DX, Xie W, Yang D, Cheng H, Lederer WJ. Quarky calcium release in the heart. Circulation Research. 108: 210-8. PMID 21148431 DOI: 10.1161/Circresaha.110.231258  0.481
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/J.Bpj.2010.12.2121  0.493
2011 Li K, Fu C, Cheng H, Tan W. Anomalous Subdiffusion of Calcium Spark in Cardiac Myocytes Cellular and Molecular Bioengineering. 4: 457-465. DOI: 10.1007/S12195-011-0174-Y  0.47
2010 Xie W, Brochet DX, Wei S, Wang X, Cheng H. Deciphering ryanodine receptor array operation in cardiac myocytes. The Journal of General Physiology. 136: 129-33. PMID 20660655 DOI: 10.1085/Jgp.201010416  0.334
2010 Lu L, Xia L, Ye X, Cheng H. Simulation of the effect of rogue ryanodine receptors on a calcium wave in ventricular myocytes with heart failure. Physical Biology. 7: 026005. PMID 20505230 DOI: 10.1088/1478-3975/7/2/026005  0.452
2010 Wang G, Zhu X, Xie W, Han P, Li K, Sun Z, Wang Y, Chen C, Song R, Cao C, Zhang J, Wu C, Liu J, Cheng H. Rad as a novel regulator of excitation-contraction coupling and beta-adrenergic signaling in heart. Circulation Research. 106: 317-27. PMID 19926875 DOI: 10.1161/Circresaha.109.208272  0.427
2010 Peng W, Zhang Y, Zheng M, Cheng H, Zhu W, Cao CM, Xiao RP. Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70. Circulation Research. 106: 102-10. PMID 19910575 DOI: 10.1161/Circresaha.109.210914  0.408
2009 Zhou P, Zhao YT, Guo YB, Xu SM, Bai SH, Lakatta EG, Cheng H, Hao XM, Wang SQ. Beta-adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 18028-33. PMID 19815510 DOI: 10.1073/Pnas.0906560106  0.509
2009 Wei C, Wang X, Chen M, Ouyang K, Song LS, Cheng H. Calcium flickers steer cell migration. Nature. 457: 901-5. PMID 19118385 DOI: 10.1038/nature07577  0.329
2009 Li K, Zhang W, Liu J, Wang W, Xie W, Fang H, Wang Y, Zheng M, Tan W, Cheng H. Flash Sniper: Automated Detection and Analysis of Mitochondrial Superoxide Flash Biophysical Journal. 96: 531a-532a. DOI: 10.1016/J.Bpj.2008.12.2743  0.324
2009 Fang H, Zhang W, Wang X, Wang W, Li K, Wang Y, Zhang X, Shang S, Tian X, Zhou J, Weisleder N, Ma J, Zheng M, Chen M, Cheng H. In vivo Imaging of Superoxide Flashes in Skeletal Muscle Biophysical Journal. 96: 530a. DOI: 10.1016/J.Bpj.2008.12.2737  0.352
2009 Wei S, Chen B, Kutschke W, Weiss R, Lederer W, Anderson M, Cheng H, Song L. Cellular Mechanism of Ca2+−Dependent Arrhythmogenesis in Failing Myocytes of Aortic Banding Rats Biophysical Journal. 96: 513a. DOI: 10.1016/J.Bpj.2008.12.2645  0.437
2009 Brochet DX, Yang D, Xie W, Cheng H, Lederer W. Quarky Calcium Sparks in Heart Biophysical Journal. 96: 21a-22a. DOI: 10.1016/J.Bpj.2008.12.1014  0.487
2008 Sheu SS, Wang W, Cheng H, Dirksen RT. Superoxide flashes: illuminating new insights into cardiac ischemia/reperfusion injury. Future Cardiology. 4: 551-554. PMID 19649173 DOI: 10.2217/14796678.4.6.551  0.38
2008 Cheng H, Lederer WJ. Calcium sparks. Physiological Reviews. 88: 1491-545. PMID 18923188 DOI: 10.1152/physrev.00030.2007  0.413
2008 Wang W, Fang H, Groom L, Cheng A, Zhang W, Liu J, Wang X, Li K, Han P, Zheng M, Yin J, Wang W, Mattson MP, Kao JP, Lakatta EG, ... ... Cheng H, et al. Superoxide flashes in single mitochondria. Cell. 134: 279-90. PMID 18662543 DOI: 10.1016/J.Cell.2008.06.017  0.332
2008 Yan Y, Liu J, Wei C, Li K, Xie W, Wang Y, Cheng H. Bidirectional regulation of Ca2+ sparks by mitochondria-derived reactive oxygen species in cardiac myocytes. Cardiovascular Research. 77: 432-41. PMID 18006452 DOI: 10.1093/Cvr/Cvm047  0.498
2008 Luo D, Yang D, Lan X, Li K, Li X, Chen J, Zhang Y, Xiao RP, Han Q, Cheng H. Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes. Cell Calcium. 43: 165-74. PMID 17583790 DOI: 10.1016/J.Ceca.2007.04.017  0.469
2007 Xiao B, Tian X, Xie W, Jones PP, Cai S, Wang X, Jiang D, Kong H, Zhang L, Chen K, Walsh MP, Cheng H, Chen SR. Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release. The Journal of Biological Chemistry. 282: 30256-64. PMID 17693412 DOI: 10.1074/Jbc.M703510200  0.489
2007 Zhao G, Zhao Y, Pan B, Liu J, Huang X, Zhang X, Cao C, Hou N, Wu C, Zhao KS, Cheng H. Hypersensitivity of BKCa to Ca2+ sparks underlies hyporeactivity of arterial smooth muscle in shock. Circulation Research. 101: 493-502. PMID 17641230 DOI: 10.1161/Circresaha.107.157271  0.474
2007 Shen T, Zheng M, Cao C, Chen C, Tang J, Zhang W, Cheng H, Chen KH, Xiao RP. Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis. The Journal of Biological Chemistry. 282: 23354-61. PMID 17562700 DOI: 10.1074/Jbc.M702657200  0.328
2007 Weisleder N, Ferrante C, Hirata Y, Collet C, Chu Y, Cheng H, Takeshima H, Ma J. Systemic ablation of RyR3 alters Ca2+ spark signaling in adult skeletal muscle. Cell Calcium. 42: 548-55. PMID 17412417 DOI: 10.1016/J.Ceca.2007.01.009  0.431
2007 Zhu W, Woo AY, Yang D, Cheng H, Crow MT, Xiao RP. Activation of CaMKIIdeltaC is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis. The Journal of Biological Chemistry. 282: 10833-9. PMID 17296607 DOI: 10.1074/Jbc.M611507200  0.433
2007 Yang D, Zhu WZ, Xiao B, Brochet DX, Chen SR, Lakatta EG, Xiao RP, Cheng H. Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes. Circulation Research. 100: 399-407. PMID 17234969 DOI: 10.1161/01.Res.0000258022.13090.55  0.489
2007 Tocchetti CG, Wang W, Froehlich JP, Huke S, Aon MA, Wilson GM, Di Benedetto G, O'Rourke B, Gao WD, Wink DA, Toscano JP, Zaccolo M, Bers DM, Valdivia HH, Cheng H, et al. Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling. Circulation Research. 100: 96-104. PMID 17138943 DOI: 10.1161/01.Res.0000253904.53601.C9  0.507
2007 Tan W, Fu C, Fu C, Xie W, Cheng H. An anomalous subdiffusion model for calcium spark in cardiac myocytes Applied Physics Letters. 91: 183901. DOI: 10.1063/1.2805208  0.483
2006 Cheng H, Wei S, Wei L, Verkhratsky A. Calcium signaling in physiology and pathophysiology. Acta Pharmacologica Sinica. 27: 767-772. PMID 16787558 DOI: 10.1111/J.1745-7254.2006.00399.X  0.443
2006 Feng Z, Wei C, Chen X, Wang J, Cheng H, Zhang X, Hong Q, Shi S, Fu B, Wei R. Essential role of Ca2+ release channels in angiotensin II-induced Ca2+ oscillations and mesangial cell contraction. Kidney International. 70: 130-8. PMID 16723987 DOI: 10.1038/Sj.Ki.5000342  0.486
2006 Song LS, Sobie EA, McCulle S, Lederer WJ, Balke CW, Cheng H. Orphaned ryanodine receptors in the failing heart. Proceedings of the National Academy of Sciences of the United States of America. 103: 4305-10. PMID 16537526 DOI: 10.1073/Pnas.0509324103  0.479
2006 Xiao B, Zhong G, Obayashi M, Yang D, Chen K, Walsh MP, Shimoni Y, Cheng H, Ter Keurs H, Chen SR. Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts. The Biochemical Journal. 396: 7-16. PMID 16483256 DOI: 10.1042/Bj20060116  0.308
2006 Vinogradova TM, Lyashkov AE, Zhu W, Ruknudin AM, Sirenko S, Yang D, Deo S, Barlow M, Johnson S, Caffrey JL, Zhou YY, Xiao RP, Cheng H, Stern MD, Maltsev VA, et al. High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cells. Circulation Research. 98: 505-14. PMID 16424365 DOI: 10.1161/01.Res.0000204575.94040.D1  0.486
2005 Ouyang K, Zheng H, Qin X, Zhang C, Yang D, Wang X, Wu C, Zhou Z, Cheng H. Ca2+ sparks and secretion in dorsal root ganglion neurons. Proceedings of the National Academy of Sciences of the United States of America. 102: 12259-64. PMID 16103366 DOI: 10.1073/Pnas.0408494102  0.484
2005 Song LS, Pi Y, Kim SJ, Yatani A, Guatimosim S, Kudej RK, Zhang Q, Cheng H, Hittinger L, Ghaleh B, Vatner DE, Lederer WJ, Vatner SF. Paradoxical cellular Ca2+ signaling in severe but compensated canine left ventricular hypertrophy. Circulation Research. 97: 457-64. PMID 16051885 DOI: 10.1161/01.Res.0000179722.79295.D4  0.483
2005 Zhu WZ, Chakir K, Zhang S, Yang D, Lavoie C, Bouvier M, Hébert TE, Lakatta EG, Cheng H, Xiao RP. Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circulation Research. 97: 244-51. PMID 16002745 DOI: 10.1161/01.Res.0000176764.38934.86  0.305
2005 Wang X, Weisleder N, Collet C, Zhou J, Chu Y, Hirata Y, Zhao X, Pan Z, Brotto M, Cheng H, Ma J. Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle. Nature Cell Biology. 7: 525-30. PMID 15834406 DOI: 10.1038/Ncb1254  0.473
2005 Xiao B, Jiang MT, Zhao M, Yang D, Sutherland C, Lai FA, Walsh MP, Warltier DC, Cheng H, Chen SR. Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure. Circulation Research. 96: 847-55. PMID 15790957 DOI: 10.1161/01.Res.0000163276.26083.E8  0.338
2005 Ouyang K, Wu C, Cheng H. Ca(2+)-induced Ca(2+) release in sensory neurons: low gain amplification confers intrinsic stability. The Journal of Biological Chemistry. 280: 15898-902. PMID 15749692 DOI: 10.1074/Jbc.C500026200  0.472
2005 Brochet DX, Yang D, Di Maio A, Lederer WJ, Franzini-Armstrong C, Cheng H. Ca2+ blinks: rapid nanoscopic store calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 3099-104. PMID 15710901 DOI: 10.1073/Pnas.0500059102  0.497
2005 Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J, Chen J, Xiao RP, ... Cheng H, et al. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 120: 59-72. PMID 15652482 DOI: 10.1016/J.Cell.2004.11.036  0.355
2004 Wang W, Zhu W, Wang S, Yang D, Crow MT, Xiao RP, Cheng H. Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway. Circulation Research. 95: 798-806. PMID 15375008 DOI: 10.1161/01.Res.0000145361.50017.Aa  0.443
2004 Jiang D, Xiao B, Yang D, Wang R, Choi P, Zhang L, Cheng H, Chen SR. RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR). Proceedings of the National Academy of Sciences of the United States of America. 101: 13062-7. PMID 15322274 DOI: 10.1073/Pnas.0402388101  0.49
2004 Wang SQ, Wei C, Zhao G, Brochet DX, Shen J, Song LS, Wang W, Yang D, Cheng H. Imaging microdomain Ca2+ in muscle cells. Circulation Research. 94: 1011-22. PMID 15117829 DOI: 10.1161/01.Res.0000125883.68447.A1  0.496
2004 Stern MD, Cheng H. Putting out the fire: what terminates calcium-induced calcium release in cardiac muscle? Cell Calcium. 35: 591-601. PMID 15110149 DOI: 10.1016/J.Ceca.2004.01.013  0.371
2004 Wang SQ, Stern MD, Ríos E, Cheng H. The quantal nature of Ca2+ sparks and in situ operation of the ryanodine receptor array in cardiac cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 3979-84. PMID 15004280 DOI: 10.1073/Pnas.0306157101  0.491
2004 Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD. Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. The Embo Journal. 23: 885-96. PMID 14963485 DOI: 10.1038/Sj.Emboj.7600054  0.349
2004 Shen JX, Wang S, Song LS, Han T, Cheng H. Polymorphism of Ca2+ sparks evoked from in-focus Ca2+ release units in cardiac myocytes. Biophysical Journal. 86: 182-90. PMID 14695261 DOI: 10.1016/S0006-3495(04)74095-3  0.478
2003 Zhu WZ, Wang SQ, Chakir K, Yang D, Zhang T, Brown JH, Devic E, Kobilka BK, Cheng H, Xiao RP. Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II. The Journal of Clinical Investigation. 111: 617-25. PMID 12618516 DOI: 10.1172/Jci16326  0.411
2003 Yang D, Song LS, Zhu WZ, Chakir K, Wang W, Wu C, Wang Y, Xiao RP, Chen SR, Cheng H. Calmodulin regulation of excitation-contraction coupling in cardiac myocytes. Circulation Research. 92: 659-67. PMID 12609973 DOI: 10.1161/01.Res.0000064566.91495.0C  0.496
2002 Rengifo J, Rosales R, González A, Cheng H, Stern MD, Ríos E. Intracellular Ca(2+) release as irreversible Markov process. Biophysical Journal. 83: 2511-21. PMID 12414685 DOI: 10.1016/S0006-3495(02)75262-4  0.476
2002 Wang SQ, Lakatta EG, Cheng H, Zhou ZQ. Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators. The Journal of Experimental Biology. 205: 2957-62. PMID 12200399  0.391
2002 Cheng H, Wang SQ. Calcium signaling between sarcolemmal calcium channels and ryanodine receptors in heart cells. Frontiers in Bioscience : a Journal and Virtual Library. 7: d1867-78. PMID 12161336 DOI: 10.2741/Cheng  0.498
2002 Wang SQ, Song LS, Xu L, Meissner G, Lakatta EG, Ríos E, Stern MD, Cheng H. Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks. Biophysical Journal. 83: 242-51. PMID 12080116 DOI: 10.1016/S0006-3495(02)75165-5  0.464
2002 Pan Z, Yang D, Nagaraj RY, Nosek TA, Nishi M, Takeshima H, Cheng H, Ma J. Dysfunction of store-operated calcium channel in muscle cells lacking mg29 Nature Cell Biology. 4: 379-383. PMID 11988740 DOI: 10.1038/Ncb788  0.334
2002 Liao P, Wang S, Wang S, Zheng M, Zheng M, Zhang S, Cheng H, Wang Y, Xiao R. p38 Mitogen-Activated Protein Kinase Mediates a Negative Inotropic Effect in Cardiac Myocytes Circulation Research. 90: 190-196. PMID 11834712 DOI: 10.1161/Hh0202.104220  0.395
2002 Song LS, Guia A, Muth JN, Rubio M, Wang SQ, Xiao RP, Josephson IR, Lakatta EG, Schwartz A, Cheng H. Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel. Circulation Research. 90: 174-81. PMID 11834710 DOI: 10.1161/Hh0202.103230  0.5
2002 Lakatta EG, Wang SQ, Song Ls, Stern M, Cheng H. S4-1 Microdomain Ca2+ signaling: The essence of cardiac excitation contraction coupling Journal of Molecular and Cellular Cardiology. 34. DOI: 10.1016/S0022-2828(02)90273-7  0.44
2001 Haak LL, Song LS, Molinski TF, Pessah IN, Cheng H, Russell JT. Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3860-70. PMID 11356874 DOI: 10.1523/Jneurosci.21-11-03860.2001  0.426
2001 Song LS, Wang SQ, Xiao RP, Spurgeon H, Lakatta E, Cheng H. β-Adrenergic Stimulation Synchronizes Intracellular Ca2+ Release During Excitation-Contraction Coupling in Cardiac Myocytes Circulation Research. 88: 794-801. PMID 11325871 DOI: 10.1161/Hh0801.090461  0.482
2001 Wang S, Song L, Lakatta EG, Cheng H. Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature. 410: 592-596. PMID 11279498 DOI: 10.1038/35069083  0.492
2001 Ríos E, Shirokova N, Kirsch WG, Pizarro G, Stern MD, Cheng H, González A. A preferred amplitude of calcium sparks in skeletal muscle. Biophysical Journal. 80: 169-83. PMID 11159393 DOI: 10.1016/S0006-3495(01)76005-5  0.324
2001 Chen-Izu Y, Xiao RP, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG. G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophysical Journal. 79: 2547-56. PMID 11053129 DOI: 10.1016/S0006-3495(00)76495-2  0.342
2001 Wang S, Lakatta E, Cheng H. Post-spark refractoriness of a single Ca2+-release unit in cardiac myocytes Journal of Molecular and Cellular Cardiology. 33: A128. DOI: 10.1016/S0022-2828(01)90511-5  0.449
2001 Song L, Wang S, Iakatta EG, Cheng H. β-Adrenergic stimulation synchronizes intracellular Ca2+ release during E-C coupling in heart cells Journal of Molecular and Cellular Cardiology. 33: A113. DOI: 10.1016/S0022-2828(01)90451-1  0.41
2000 Vinogradova TM, Zhou Y, Bogdanov KY, Yang D, Kuschel M, Cheng H, Xiao R. Sinoatrial Node Pacemaker Activity Requires Ca2+/Calmodulin-Dependent Protein Kinase II Activation Circulation Research. 87: 760-767. PMID 11055979 DOI: 10.1161/01.Res.87.9.760  0.43
2000 Hagemann D, Kuschel M, Kuramochi T, Zhu W, Cheng H, Xiao R. Frequency-encoding Thr17 Phospholamban Phosphorylation Is Independent of Ser16 Phosphorylation in Cardiac Myocytes Journal of Biological Chemistry. 275: 22532-22536. PMID 10825152 DOI: 10.1074/Jbc.C000253200  0.323
2000 González A, Kirsch WG, Shirokova N, Pizarro G, Brum G, Pessah IN, Stern MD, Cheng H, Ríos E. Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 97: 4380-5. PMID 10759554 DOI: 10.1073/Pnas.070056497  0.39
2000 Song L, Ren G, Chen Z, Chen Z, Zhou Z, Cheng H. Electrophysiological effects of protopine in cardiac myocytes: inhibition of multiple cation channel currents. British Journal of Pharmacology. 129: 893-900. PMID 10696087 DOI: 10.1038/Sj.Bjp.0703132  0.386
2000 Xiao RP, Cheng H, Zhou YY, Kuschel M, Lakatta EG. Recent advances in cardiac beta(2)-adrenergic signal transduction. Circulation Research. 85: 1092-100. PMID 10571541 DOI: 10.1161/01.Res.85.11.1092  0.325
1999 Zhou YY, Song LS, Lakatta EG, Xiao RP, Cheng H. Constitutive β2‐adrenergic signalling enhances sarcoplasmic reticulum Ca2+ cycling to augment contraction in mouse heart The Journal of Physiology. 521: 351-361. PMID 10581307 DOI: 10.1111/J.1469-7793.1999.00351.X  0.518
1999 Zhou YY, Cheng H, Song LS, Wang D, Lakatta E, Xiao RP. Spontaneous β2-Adrenergic Signaling Fails To Modulate L-Type Ca2+ Current in Mouse Ventricular Myocytes Molecular Pharmacology. 56: 485-493. PMID 10462536 DOI: 10.1124/Mol.56.3.485  0.364
1999 Stern MD, Song LS, Cheng H, Sham JS, Yang HT, Boheler KR, Ríos E. Local control models of cardiac excitation-contraction coupling. A possible role for allosteric interactions between ryanodine receptors. The Journal of General Physiology. 113: 469-89. PMID 10051521 DOI: 10.1085/Jgp.113.3.469  0.349
1999 Shirokova N, González A, Kirsch WG, Ríos E, Pizarro G, Stern MD, Cheng H. Calcium sparks: release packets of uncertain origin and fundamental role. The Journal of General Physiology. 113: 377-84. PMID 10051514 DOI: 10.1085/Jgp.113.3.377  0.414
1999 Xiao RP, Avdonin P, Zhou YY, Cheng H, Akhter SA, Eschenhagen T, Lefkowitz RJ, Koch WJ, Lakatta EG. Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes. Circulation Research. 84: 43-52. PMID 9915773 DOI: 10.1161/01.Res.84.1.43  0.405
1998 Song LS, Sham JS, Stern MD, Lakatta EG, Cheng H. Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes. The Journal of Physiology. 512: 677-91. PMID 9769413 DOI: 10.1111/J.1469-7793.1998.677Bd.X  0.479
1998 Smith GD, Keizer JE, Stern MD, Lederer WJ, Cheng H. A simple numerical model of calcium spark formation and detection in cardiac myocytes. Biophysical Journal. 75: 15-32. PMID 9649364 DOI: 10.1016/S0006-3495(98)77491-0  0.49
1997 Song LS, Stern MD, Lakatta EG, Cheng H. Partial depletion of sarcoplasmic reticulum calcium does not prevent calcium sparks in rat ventricular myocytes. The Journal of Physiology. 505: 665-75. PMID 9457644 DOI: 10.1111/J.1469-7793.1997.665Ba.X  0.316
1997 Zhou YY, Cheng H, Bogdanov KY, Hohl C, Altschuld R, Lakatta EG, Xiao RP. Localized cAMP-dependent signaling mediates beta 2-adrenergic modulation of cardiac excitation-contraction coupling American Journal of Physiology-Heart and Circulatory Physiology. 273. PMID 9321856 DOI: 10.1152/Ajpheart.1997.273.3.H1611  0.347
1997 Xiao RP, Valdivia HH, Bogdanov K, Valdivia C, Lakatta EG, Cheng H. The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart. The Journal of Physiology. 500: 343-54. PMID 9147322 DOI: 10.1113/Jphysiol.1997.Sp022025  0.504
1997 Gómez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science (New York, N.Y.). 276: 800-6. PMID 9115206 DOI: 10.1126/Science.276.5313.800  0.349
1996 Gómez AM, Cheng H, Lederer WJ, Bers DM. Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+]i decline during Ca2+ sparks in rat ventricular myocytes. The Journal of Physiology. 496: 575-81. PMID 8910239 DOI: 10.1113/Jphysiol.1996.Sp021708  0.466
1996 Cheng H, Lederer MR, Xiao RP, Gómez AM, Zhou YY, Ziman B, Spurgeon H, Lakatta EG, Lederer WJ. Excitation-contraction coupling in heart: new insights from Ca2+ sparks. Cell Calcium. 20: 129-40. PMID 8889204 DOI: 10.1016/S0143-4160(96)90102-5  0.503
1996 Cheng H, Lederer MR, Lederer WJ, Cannell MB. Calcium sparks and [Ca2+]i waves in cardiac myocytes. The American Journal of Physiology. 270: C148-59. PMID 8772440 DOI: 10.1152/Ajpcell.1996.270.1.C148  0.472
1996 Lederer WJ, He S, Luo S, duBell W, Kofuji P, Kieval R, Neubauer CF, Ruknudin A, Cheng H, Cannell MB, Rogers TB, Schulze DH. The molecular biology of the Na(+)-Ca2+ exchanger and its functional roles in heart, smooth muscle cells, neurons, glia, lymphocytes, and nonexcitable cells. Annals of the New York Academy of Sciences. 779: 7-17. PMID 8659882 DOI: 10.1111/J.1749-6632.1996.Tb44764.X  0.399
1996 Santana LF, Cheng H, Gómez AM, Cannell MB, Lederer WJ. Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling. Circulation Research. 78: 166-71. PMID 8603501 DOI: 10.1161/01.Res.78.1.166  0.481
1996 Klein MG, Cheng H, Santana LF, Jiang YH, Lederer WJ, Schneider MF. Two mechanisms of quantized calcium release in skeletal muscle. Nature. 379: 455-8. PMID 8559251 DOI: 10.1038/379455A0  0.42
1995 Cheng H, Cannell MB, Lederer WJ. Partial inhibition of Ca2+ current by methoxyverapamil (D600) reveals spatial nonuniformities in [Ca2+]i during excitation-contraction coupling in cardiac myocytes. Circulation Research. 76: 236-41. PMID 7834834 DOI: 10.1161/01.Res.76.2.236  0.489
1995 Cheng H, Fill M, Valdivia H, Lederer WJ. Models of Ca2+ release channel adaptation. Science (New York, N.Y.). 267: 2009-10. PMID 7701326 DOI: 10.1126/Science.7701326  0.405
1995 Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. Relaxation of arterial smooth muscle by calcium sparks. Science (New York, N.Y.). 270: 633-7. PMID 7570021 DOI: 10.1126/Science.270.5236.633  0.462
1994 Piston DW, Kirby MS, Cheng H, Lederer WJ, Webb WW. Two-photon-excitation fluorescence imaging of three-dimensional calcium-ion activity. Applied Optics. 33: 662-9. PMID 20862061 DOI: 10.1364/Ao.33.000662  0.383
1994 Niggli E, Piston DW, Kirby MS, Cheng H, Sandison DR, Webb WW, Lederer WJ. A confocal laser scanning microscope designed for indicators with ultraviolet excitation wavelengths. The American Journal of Physiology. 266: C303-10. PMID 8304426 DOI: 10.1152/Ajpcell.1994.266.1.C303  0.332
1994 Xiao RP, Cheng H, Lederer WJ, Suzuki T, Lakatta EG. Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx. Proceedings of the National Academy of Sciences of the United States of America. 91: 9659-63. PMID 7937825 DOI: 10.1073/Pnas.91.20.9659  0.479
1994 Cheng H, Cannell MB, Lederer WJ. Propagation of excitation-contraction coupling into ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 428: 415-7. PMID 7816564 DOI: 10.1007/Bf00724526  0.495
1993 Cheng H, Lederer WJ, Cannell MB. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science (New York, N.Y.). 262: 740-4. PMID 8235594 DOI: 10.1126/Science.8235594  0.326
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