Year |
Citation |
Score |
2023 |
Fleming Martinez AK, Storz P. Protein kinase D1 - A targetable mediator of pancreatic cancer development. Biochimica Et Biophysica Acta. Molecular Cell Research. 1871: 119646. PMID 38061566 DOI: 10.1016/j.bbamcr.2023.119646 |
0.416 |
|
2022 |
Döppler HR, Liou GY, Storz P. Generation of Hydrogen Peroxide and Downstream Protein Kinase D1 Signaling Is a Common Feature of Inducers of Pancreatic Acinar-to-Ductal Metaplasia. Antioxidants (Basel, Switzerland). 11. PMID 35052641 DOI: 10.3390/antiox11010137 |
0.368 |
|
2021 |
Fleming Martinez AK, Döppler HR, Bastea LI, Edenfield B, Patel T, Leitges M, Liou GY, Storz P. Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells. Iscience. 24: 102019. PMID 33521594 DOI: 10.1016/j.isci.2020.102019 |
0.328 |
|
2021 |
Fleming Martinez AK, Döppler HR, Bastea LI, Edenfield B, Patel T, Leitges M, Liou GY, Storz P. Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells. Iscience. 24: 102019. PMID 33521594 DOI: 10.1016/j.isci.2020.102019 |
0.328 |
|
2019 |
Lieb WS, Lungu C, Tamas R, Berreth H, Rathert P, Storz P, Olayioye MA, Hausser A. The GEF-H1/PKD3 signaling pathway promotes the maintenance of triple-negative breast cancer stem cells. International Journal of Cancer. PMID 31745977 DOI: 10.1002/Ijc.32798 |
0.394 |
|
2019 |
Bastea LI, Hollant LMA, Döppler HR, Reid EM, Storz P. Sangivamycin and its derivatives inhibit Haspin-Histone H3-survivin signaling and induce pancreatic cancer cell death. Scientific Reports. 9: 16588. PMID 31719634 DOI: 10.1038/S41598-019-53223-0 |
0.362 |
|
2019 |
Wang Y, Hoeppner LH, Angom RS, Wang E, Dutta S, Doeppler HR, Wang F, Shen T, Scarisbrick IA, Guha S, Storz P, Bhattacharya R, Mukhopadhyay D. Protein kinase D up-regulates transcription of VEGF receptor-2 in endothelial cells by suppressing nuclear localization of the transcription factor AP2β. The Journal of Biological Chemistry. PMID 31492751 DOI: 10.1074/Jbc.Ra119.010152 |
0.41 |
|
2019 |
Liu X, Clemens DL, Grunkemeyer JA, Price JD, O'Connell K, Chapman NM, Storz P, Wen H, Cox JL, Reid WL, Hollingsworth MA, Thayer S. Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis. Scientific Reports. 9: 10656. PMID 31337812 DOI: 10.1038/S41598-019-46933-Y |
0.322 |
|
2019 |
Pandey V, Storz P. Targeting the tumor microenvironment in pancreatic ductal adenocarcinoma. Expert Review of Anticancer Therapy. 19: 473-482. PMID 31148495 DOI: 10.1080/14737140.2019.1622417 |
0.32 |
|
2019 |
Fleming Martinez AK, Storz P. Mimicking and Manipulating Pancreatic Acinar-to-Ductal Metaplasia in 3-dimensional Cell Culture. Journal of Visualized Experiments : Jove. PMID 30799859 DOI: 10.3791/59096 |
0.343 |
|
2019 |
Bastea LI, Liou GY, Pandey V, Fleming AK, Von Roemeling CA, Doeppler H, Li Z, Qiu Y, Edenfield B, Copland JA, Tun HW, Storz P. Pomalidomide alters pancreatic macrophage populations to generate an immune-responsive environment at precancerous and cancerous lesions. Cancer Research. PMID 30696657 DOI: 10.1158/0008-5472.Can-18-1153 |
0.315 |
|
2018 |
Durand N, Borges S, Hall T, Bastea L, Döppler H, Edenfield BH, Thompson EA, Geiger X, Storz P. The phosphorylation status of PIP5K1C at serine 448 can be predictive for invasive ductal carcinoma of the breast. Oncotarget. 9: 36358-36370. PMID 30555634 DOI: 10.18632/Oncotarget.26357 |
0.424 |
|
2018 |
Storz P. Protein kinase D1: gatekeeper of the epithelial phenotype and key regulator of cancer metastasis? British Journal of Cancer. 118: 459-461. PMID 29465085 DOI: 10.1038/Bjc.2018.1 |
0.479 |
|
2017 |
Durand N, Bastea LI, Döppler H, Eiseler T, Storz P. Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion. Scientific Reports. 7: 9524. PMID 28842658 DOI: 10.1038/S41598-017-10210-7 |
0.541 |
|
2017 |
Fleming AK, Storz P. Protein kinase C isoforms in the normal pancreas and in pancreatic disease. Cellular Signalling. 40: 1-9. PMID 28826907 DOI: 10.1016/J.Cellsig.2017.08.005 |
0.384 |
|
2017 |
Ding L, Liou GY, Schmitt DM, Storz P, Zhang JS, Billadeau DD. Glycogen synthase kinase-3β ablation limits pancreatitis induced acinar-to-ductal metaplasia. The Journal of Pathology. PMID 28639695 DOI: 10.1002/Path.4928 |
0.372 |
|
2017 |
Cobbaut M, Derua R, Döppler H, Lou HJ, Vandoninck S, Storz P, Turk BE, Seufferlein T, Waelkens E, Janssens V, Van Lint J. Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop. Scientific Reports. 7: 887. PMID 28428613 DOI: 10.1038/S41598-017-00800-W |
0.51 |
|
2017 |
Döppler H, Storz P. Mitochondrial and Oxidative Stress-Mediated Activation of Protein Kinase D1 and Its Importance in Pancreatic Cancer. Frontiers in Oncology. 7: 41. PMID 28361035 DOI: 10.3389/Fonc.2017.00041 |
0.489 |
|
2017 |
Storz P. Acinar cell plasticity and development of pancreatic ductal adenocarcinoma. Nature Reviews. Gastroenterology & Hepatology. 14: 296-304. PMID 28270694 DOI: 10.1038/Nrgastro.2017.12 |
0.325 |
|
2017 |
Storz P. KRas, ROS and the initiation of pancreatic cancer. Small Gtpases. 8: 38-42. PMID 27215184 DOI: 10.1080/21541248.2016.1192714 |
0.362 |
|
2017 |
Cobbaut M, Derua R, Waelkens E, Störz P, Janssens V, Lint JV. Abstract B08: Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment Cancer Research. 77. DOI: 10.1158/1538-7445.Newfront17-B08 |
0.552 |
|
2016 |
Durand N, Storz P. Targeting reactive oxygen species in development and progression of pancreatic cancer. Expert Review of Anticancer Therapy. PMID 27841037 DOI: 10.1080/14737140.2017.1261017 |
0.345 |
|
2016 |
Durand N, Bastea LI, Long J, Döppler H, Ling K, Storz P. Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ. Scientific Reports. 6: 35963. PMID 27775029 DOI: 10.1038/Srep35963 |
0.514 |
|
2016 |
Colonne PM, Winchell CG, Graham JG, Onyilagha FI, MacDonald LJ, Doeppler HR, Storz P, Kurten RC, Beare PA, Heinzen RA, Voth DE. Vasodilator-Stimulated Phosphoprotein Activity Is Required for Coxiella burnetii Growth in Human Macrophages. Plos Pathogens. 12: e1005915. PMID 27711191 DOI: 10.1371/Journal.Ppat.1005915 |
0.41 |
|
2016 |
Döppler H, Panayiotou R, Reid EM, Maimo W, Bastea L, Storz P. The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer. Scientific Reports. 6: 33758. PMID 27649783 DOI: 10.1038/Srep33758 |
0.432 |
|
2016 |
Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, ... Storz P, et al. Legumain is Activated in Macrophages during Pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00047.2016. PMID 27514475 DOI: 10.1152/Ajpgi.00047.2016 |
0.331 |
|
2016 |
Liou GY, Storz P, Leitges M. A bright future for protein kinase D1 as a drug target to prevent or treat pancreatic cancer. Molecular & Cellular Oncology. 3: e1035477. PMID 27308552 DOI: 10.1080/23723556.2015.1035477 |
0.475 |
|
2016 |
Yushi Q, Li Z, Von Roemeling CA, Doeppler H, Marlow LA, Kim BY, Radisky DC, Storz P, Copland JA, Tun HW. Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma. Oncotarget. PMID 27050077 DOI: 10.18632/Oncotarget.8537 |
0.357 |
|
2016 |
Liou GY, Döppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P. Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions. Cell Reports. PMID 26947075 DOI: 10.1016/J.Celrep.2016.02.029 |
0.334 |
|
2016 |
Durand N, Borges S, Storz P. Protein Kinase D Enzymes as Regulators of EMT and Cancer Cell Invasion. Journal of Clinical Medicine. 5. PMID 26848698 DOI: 10.3390/Jcm5020020 |
0.477 |
|
2016 |
Liou G, Doeppler H, DelGirono KE, Crawford HC, Murphy MP, Storz P. Abstract PR01: Oncogenic Kras-induced mitochondrial oxidative stress in pancreatic acini modulates the formation of precancerous lesions through autocrine EGFR signaling Metabolism-Clinical and Experimental. 76. DOI: 10.1158/1538-7445.Fbcr15-Pr01 |
0.33 |
|
2015 |
Döppler H, Bastea L, Borges S, Geiger X, Storz P. The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma. Oncotarget. 6: 29740-52. PMID 26336132 DOI: 10.18632/Oncotarget.4965 |
0.39 |
|
2015 |
Durand N, Borges S, Storz P. Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer. Cellular and Molecular Life Sciences : Cmls. 72: 4369-82. PMID 26253275 DOI: 10.1007/s00018-015-2011-2 |
0.31 |
|
2015 |
Liou GY, Storz P. Protein kinase D enzymes: novel kinase targets in pancreatic cancer. Expert Review of Gastroenterology & Hepatology. 9: 1143-6. PMID 26174103 DOI: 10.1586/17474124.2015.1069706 |
0.348 |
|
2015 |
Liou GY, Leitges M, Storz P. Pancreatic oncogenic signaling cascades converge at Protein Kinase D1. Cell Cycle (Georgetown, Tex.). 14: 1489-90. PMID 25928263 DOI: 10.1080/15384101.2015.1032646 |
0.508 |
|
2015 |
Liou GY, Döppler H, Braun UB, Panayiotou R, Scotti Buzhardt M, Radisky DC, Crawford HC, Fields AP, Murray NR, Wang QJ, Leitges M, Storz P. Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia. Nature Communications. 6: 6200. PMID 25698580 DOI: 10.1038/Ncomms7200 |
0.442 |
|
2015 |
Storz P. Targeting protein kinase C subtypes in pancreatic cancer. Expert Review of Anticancer Therapy. 15: 433-8. PMID 25604078 DOI: 10.1586/14737140.2015.1003810 |
0.45 |
|
2015 |
Liou GY, Döppler H, Necela B, Edenfield B, Zhang L, Dawson DW, Storz P. Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions. Cancer Discovery. 5: 52-63. PMID 25361845 DOI: 10.1158/2159-8290.Cd-14-0474 |
0.333 |
|
2014 |
Zheng H, Shen M, Zha YL, Li W, Wei Y, Blanco MA, Ren G, Zhou T, Storz P, Wang HY, Kang Y. PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis. Cancer Cell. 26: 358-73. PMID 25203322 DOI: 10.1016/J.Ccr.2014.07.022 |
0.438 |
|
2014 |
Döppler H, Bastea LI, Borges S, Spratley SJ, Pearce SE, Storz P. Protein kinase d isoforms differentially modulate cofilin-driven directed cell migration. Plos One. 9: e98090. PMID 24840177 DOI: 10.1371/Journal.Pone.0098090 |
0.517 |
|
2014 |
Borges S, Döppler HR, Storz P. A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells. Breast Cancer Research and Treatment. 144: 79-91. PMID 24510012 DOI: 10.1007/S10549-014-2857-2 |
0.365 |
|
2013 |
Döppler H, Storz P. Regulation of VASP by phosphorylation: consequences for cell migration. Cell Adhesion & Migration. 7: 482-6. PMID 24401601 DOI: 10.4161/Cam.27351 |
0.469 |
|
2013 |
Borges S, Döppler H, Perez EA, Andorfer CA, Sun Z, Anastasiadis PZ, Thompson E, Geiger XJ, Storz P. Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. Breast Cancer Research : Bcr. 15: R66. PMID 23971832 DOI: 10.1186/Bcr3460 |
0.418 |
|
2013 |
Borges S, Storz P. Protein kinase D isoforms: new targets for therapy in invasive breast cancers? Expert Review of Anticancer Therapy. 13: 895-8. PMID 23944680 DOI: 10.1586/14737140.2013.816460 |
0.445 |
|
2013 |
Liou GY, Döppler H, Necela B, Krishna M, Crawford HC, Raimondo M, Storz P. Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs. The Journal of Cell Biology. 202: 563-77. PMID 23918941 DOI: 10.1083/Jcb.201301001 |
0.368 |
|
2013 |
Döppler HR, Bastea LI, Lewis-Tuffin LJ, Anastasiadis PZ, Storz P. Protein kinase D1-mediated phosphorylations regulate vasodilator-stimulated phosphoprotein (VASP) localization and cell migration. The Journal of Biological Chemistry. 288: 24382-93. PMID 23846685 DOI: 10.1074/Jbc.M113.474676 |
0.501 |
|
2013 |
Bastea LI, Döppler H, Pearce SE, Durand N, Spratley SJ, Storz P. Protein kinase D-mediated phosphorylation at Ser99 regulates localization of p21-activated kinase 4. The Biochemical Journal. 455: 251-60. PMID 23841590 DOI: 10.1042/Bj20130281 |
0.534 |
|
2013 |
Storz P. Targeting the alternative NF-κB pathway in pancreatic cancer: a new direction for therapy? Expert Review of Anticancer Therapy. 13: 501-4. PMID 23617340 DOI: 10.1586/Era.13.28 |
0.419 |
|
2013 |
Ngok SP, Geyer R, Kourtidis A, Storz P, Anastasiadis PZ. Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) Syx. The Journal of Biological Chemistry. 288: 6640-50. PMID 23335514 DOI: 10.1074/Jbc.M112.432682 |
0.509 |
|
2013 |
Döppler H, Liou GY, Storz P. Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity. Plos One. 8: e53676. PMID 23301098 DOI: 10.1371/Journal.Pone.0053676 |
0.392 |
|
2013 |
Döppler H, Bastea LI, Eiseler T, Storz P. Neuregulin mediates F-actin-driven cell migration through inhibition of protein kinase D1 via Rac1 protein. The Journal of Biological Chemistry. 288: 455-65. PMID 23148218 DOI: 10.1074/Jbc.M112.397448 |
0.473 |
|
2013 |
Liou G, Doeppler H, Storz P. Abstract LB-342: Macrophage-secreted cytokines drive acinar-to-ductal metaplasia of the pancreas. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-342 |
0.362 |
|
2013 |
Kohlenberg JD, Chen Y, Best B, Storz P, Peterson RT, Silverstein R, Ren B. Abstract LB-338: A novel LPA-PKD1-FoxO1 pathway in endothelial cells provides an angiogenic switch via down-regulation of CD36 transcription and induction of arteriogenic responses . Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-338 |
0.365 |
|
2012 |
Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, Marx R, Baraban JM, Storz P, Horowitz A, Anastasiadis PZ. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. The Journal of Cell Biology. 199: 1103-15. PMID 23253477 DOI: 10.1083/Jcb.201207009 |
0.324 |
|
2012 |
Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, ... ... Storz P, et al. EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell. 22: 304-17. PMID 22975374 DOI: 10.1016/J.Ccr.2012.07.024 |
0.354 |
|
2012 |
Eiseler T, Köhler C, Nimmagadda SC, Jamali A, Funk N, Joodi G, Storz P, Seufferlein T. Protein kinase D1 mediates anchorage-dependent and -independent growth of tumor cells via the zinc finger transcription factor Snail1. The Journal of Biological Chemistry. 287: 32367-80. PMID 22791710 DOI: 10.1074/Jbc.M112.370999 |
0.502 |
|
2012 |
Marlow LA, von Roemeling CA, Cooper SJ, Zhang Y, Rohl SD, Arora S, Gonzales IM, Azorsa DO, Reddi HV, Tun HW, Dö ppler HR, Storz P, Smallridge RC, Copland JA. Foxo3a drives proliferation in anaplastic thyroid carcinoma through transcriptional regulation of cyclin A1: A paradigm shift that impacts current therapeutic strategies Journal of Cell Science. 125: 4253-4263. PMID 22718346 DOI: 10.1242/Jcs.097428 |
0.44 |
|
2012 |
Bastea LI, Döppler H, Balogun B, Storz P. Protein kinase D1 maintains the epithelial phenotype by inducing a DNA-bound, inactive SNAI1 transcriptional repressor complex. Plos One. 7: e30459. PMID 22276203 DOI: 10.1371/Journal.Pone.0030459 |
0.393 |
|
2012 |
Storz P. Abstract A82: Regulation and role of NF-KB in pancreatic cancer. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A82 |
0.486 |
|
2012 |
Nimmagadda SC, Eiseler T, Lint JV, Storz P, Seufferlein T. Abstract LB-513: Abelson Interactor 1 is a novel substrate of protein kinase D2: potential implications in tumor cell migration Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-513 |
0.456 |
|
2012 |
Borges S, Doppler H, Andorfer C, Perez E, Sun Z, Anastasiadis P, Thompson A, Geiger X, Storz P. Abstract P1-05-24: Pharmacologic reversion of epigenetic silencing of thePRKD1promoter blocks breast tumor cell invasion and metastasis. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P1-05-24 |
0.36 |
|
2011 |
Spratley SJ, Bastea LI, Döppler H, Mizuno K, Storz P. Protein kinase D regulates cofilin activity through p21-activated kinase 4. The Journal of Biological Chemistry. 286: 34254-61. PMID 21832093 DOI: 10.1074/Jbc.M111.259424 |
0.528 |
|
2011 |
Storz P. Forkhead homeobox type O transcription factors in the responses to oxidative stress. Antioxidants & Redox Signaling. 14: 593-605. PMID 20618067 DOI: 10.1089/Ars.2010.3405 |
0.377 |
|
2011 |
Spratley SJ, Storz P. Abstract 2364: Regulation of cofilin activity and tumor cell migration through protein kinase D Cancer Research. 71: 2364-2364. DOI: 10.1158/1538-7445.Am2011-2364 |
0.532 |
|
2011 |
Liou G, Storz P. Abstract 1123: Transforming growth factor α signaling in pancreatic acinar-to-ductal metaplasia Cancer Research. 71: 1123-1123. DOI: 10.1158/1538-7445.Am2011-1123 |
0.338 |
|
2011 |
Marlow L, Roemeling Cv, Zhang Y, Cooper S, Rohl S, Tun H, Storz P, Smallridge R, Copland JA. Abstract 1038: Regulation of cyclin A by FoxO3a drives proliferation in anaplastic thyroid carcinoma Cancer Research. 71: 1038-1038. DOI: 10.1158/1538-7445.Am2011-1038 |
0.404 |
|
2010 |
Liou GY, Storz P. Reactive oxygen species in cancer. Free Radical Research. 44: 479-96. PMID 20370557 DOI: 10.3109/10715761003667554 |
0.378 |
|
2010 |
Storz P. Abstract 3143: PKD as a downstream target for K-ras in pancreatic cancer Cancer Research. 70: 3143-3143. DOI: 10.1158/1538-7445.Am10-3143 |
0.382 |
|
2009 |
Storz P, Döppler H, Copland JA, Simpson KJ, Toker A. FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases. Molecular and Cellular Biology. 29: 4906-17. PMID 19564415 DOI: 10.1128/Mcb.00077-09 |
0.567 |
|
2009 |
Storz P. Protein kinase D1: a novel regulator of actin-driven directed cell migration. Cell Cycle (Georgetown, Tex.). 8: 1975-6. PMID 19550138 DOI: 10.4161/Cc.8.13.9016 |
0.474 |
|
2009 |
Eiseler T, Döppler H, Yan IK, Kitatani K, Mizuno K, Storz P. Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot Nature Cell Biology. 11: 545-556. PMID 19329994 DOI: 10.1038/Ncb1861 |
0.441 |
|
2009 |
Cowell CF, Döppler H, Yan IK, Hausser A, Umezawa Y, Storz P. Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling. Journal of Cell Science. 122: 919-28. PMID 19258390 DOI: 10.1242/Jcs.041061 |
0.483 |
|
2009 |
Eiseler T, Döppler H, Yan IK, Goodison S, Storz P. Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion Breast Cancer Research. 11. PMID 19243594 DOI: 10.1186/Bcr2232 |
0.337 |
|
2009 |
Cowell CF, Yan IK, Eiseler T, Leightner AC, Döppler H, Storz P. Loss of cell-cell contacts induces NF-kappaB via RhoA-mediated activation of protein kinase D1. Journal of Cellular Biochemistry. 106: 714-28. PMID 19173301 DOI: 10.1002/Jcb.22067 |
0.519 |
|
2008 |
Watkins JL, Lewandowski KT, Meek SE, Storz P, Toker A, Piwnica-Worms H. Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. Proceedings of the National Academy of Sciences of the United States of America. 105: 18378-83. PMID 19011111 DOI: 10.1073/Pnas.0809661105 |
0.68 |
|
2007 |
Döppler H, Storz P. A novel tyrosine phosphorylation site in protein kinase D contributes to oxidative stress-mediated activation. The Journal of Biological Chemistry. 282: 31873-81. PMID 17804414 DOI: 10.1074/Jbc.M703584200 |
0.504 |
|
2007 |
Storz P. Mitochondrial ROS--radical detoxification, mediated by protein kinase D. Trends in Cell Biology. 17: 13-8. PMID 17126550 DOI: 10.1016/J.Tcb.2006.11.003 |
0.41 |
|
2006 |
Storz P. Protein kinase D3 Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A001932.01 |
0.44 |
|
2006 |
Storz P. Protein kinase D2 Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A001931.01 |
0.44 |
|
2005 |
Storz P, Döppler H, Toker A. Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species. Molecular and Cellular Biology. 25: 8520-30. PMID 16166634 DOI: 10.1128/Mcb.25.19.8520-8530.2005 |
0.644 |
|
2005 |
Hausser A, Storz P, Märtens S, Link G, Toker A, Pfizenmaier K. Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex. Nature Cell Biology. 7: 880-6. PMID 16100512 DOI: 10.1038/Ncb1289 |
0.665 |
|
2005 |
Zhang W, Zheng S, Storz P, Min W. Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. The Journal of Biological Chemistry. 280: 19036-44. PMID 15755722 DOI: 10.1074/Jbc.M414674200 |
0.508 |
|
2005 |
Döppler H, Storz P, Li J, Comb MJ, Toker A. A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D. The Journal of Biological Chemistry. 280: 15013-9. PMID 15728188 DOI: 10.1074/Jbc.C400575200 |
0.619 |
|
2005 |
Kraft S, Fleming T, Billingsley JM, Lin SY, Jouvin MH, Storz P, Kinet JP. Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo. The Journal of Experimental Medicine. 201: 385-96. PMID 15684326 DOI: 10.1084/Jem.20042085 |
0.306 |
|
2005 |
Storz P, Döppler H, Ferran C, Grey ST, Toker A. Functional dichotomy of A20 in apoptotic and necrotic cell death Biochemical Journal. 387: 47-55. PMID 15527421 DOI: 10.1042/Bj20041443 |
0.595 |
|
2004 |
Hutti JE, Jarrell ET, Chang JD, Abbott DW, Storz P, Toker A, Cantley LC, Turk BE. A rapid method for determining protein kinase phosphorylation specificity. Nature Methods. 1: 27-9. PMID 15782149 DOI: 10.1038/Nmeth708 |
0.677 |
|
2004 |
Storz P, Döppler H, Toker A. Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB. Molecular Pharmacology. 66: 870-9. PMID 15226414 DOI: 10.1124/Mol.104.000687 |
0.692 |
|
2004 |
Wang Y, Schattenberg JM, Rigoli RM, Storz P, Czaja MJ. Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1. The Journal of Biological Chemistry. 279: 31089-97. PMID 15145937 DOI: 10.1074/Jbc.M404170200 |
0.505 |
|
2004 |
Storz P, Döppler H, Toker A. Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling. Molecular and Cellular Biology. 24: 2614-26. PMID 15024053 DOI: 10.1128/Mcb.24.7.2614-2626.2004 |
0.7 |
|
2003 |
Storz P, Toker A. NF-kappaB signaling--an alternate pathway for oxidative stress responses. Cell Cycle (Georgetown, Tex.). 2: 9-10. PMID 12695674 DOI: 10.4161/Cc.2.1.234 |
0.582 |
|
2003 |
Storz P, Döppler H, Johannes FJ, Toker A. Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation. The Journal of Biological Chemistry. 278: 17969-76. PMID 12637538 DOI: 10.1074/Jbc.M213224200 |
0.684 |
|
2003 |
Storz P, Toker A. Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway. The Embo Journal. 22: 109-20. PMID 12505989 DOI: 10.1093/Emboj/Cdg009 |
0.678 |
|
2002 |
Storz P, Toker A. 3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling. Frontiers in Bioscience : a Journal and Virtual Library. 7: d886-902. PMID 11897568 DOI: 10.2741/Storz |
0.69 |
|
2002 |
Brändlin I, Hübner S, Eiseler T, Martinez-Moya M, Horschinek A, Hausser A, Link G, Rupp S, Storz P, Pfizenmaier K, Johannes FJ. Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways. The Journal of Biological Chemistry. 277: 6490-6. PMID 11741879 DOI: 10.1074/Jbc.M106083200 |
0.513 |
|
2001 |
Storz P, Döppler H, Horn-Müller J, Müller G, Pfizenmaier K. TNF down-regulation of receptor tyrosine kinase-dependent mitogenic signal pathways as an important step in cytostasis induction and commitment to apoptosis of Kym-1 rhabdomyosarcoma cells. Cell Death and Differentiation. 7: 955-65. PMID 11279542 DOI: 10.1038/sj.cdd.4400732 |
0.327 |
|
2001 |
Hausser A, Storz P, Hübner S, Braendlin I, Martinez-Moya M, Link G, Johannes FJ. Protein kinase C mu selectively activates the mitogen-activated protein kinase (MAPK) p42 pathway. Febs Letters. 492: 39-44. PMID 11248233 DOI: 10.1016/S0014-5793(01)02219-0 |
0.499 |
|
2000 |
Storz P, Hausser A, Link G, Dedio J, Ghebrehiwet B, Pfizenmaier K, Johannes FJ. Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32. The Journal of Biological Chemistry. 275: 24601-7. PMID 10831594 DOI: 10.1074/Jbc.M002964200 |
0.331 |
|
1999 |
Johannes FJ, Hausser A, Storz P, Truckenmüller L, Link G, Kawakami T, Pfizenmaier K. Bruton's tyrosine kinase (Btk) associates with protein kinase C mu. Febs Letters. 461: 68-72. PMID 10561498 DOI: 10.1016/S0014-5793(99)01424-6 |
0.312 |
|
1999 |
Hausser A, Storz P, Link G, Stoll H, Liu YC, Altman A, Pfizenmaier K, Johannes FJ. Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteins. The Journal of Biological Chemistry. 274: 9258-64. PMID 10092600 DOI: 10.1074/jbc.274.14.9258 |
0.406 |
|
1998 |
Müller G, Storz P, Bourteele S, Döppler H, Pfizenmaier K, Mischak H, Philipp A, Kaiser C, Kolch W. Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling Embo Journal. 17: 732-742. PMID 9450998 DOI: 10.1093/emboj/17.3.732 |
0.386 |
|
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