Ronald C. Conaway - Publications

Affiliations: 
Stowers Institute for Medical Research, Kansas City, Missouri, Kansas City, MO, United States 

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Conaway RC, Conaway JW. The hunt for RNA polymerase II elongation factors: a historical perspective. Nature Structural & Molecular Biology. PMID 31439940 DOI: 10.1038/s41594-019-0283-1  1
2019 Tettey TT, Gao X, Shao W, Li H, Story BA, Chitsazan AD, Glaser RL, Goode ZH, Seidel CW, Conaway RC, Zeitlinger J, Blanchette M, Conaway JW. A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing. Cell Reports. 27: 3770-3779.e7. PMID 31242411 DOI: 10.1016/j.celrep.2019.05.099  1
2019 Noe Gonzalez M, Conaway JW, Conaway RC. Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events. Journal of Visualized Experiments : Jove. PMID 31132066 DOI: 10.3791/59497  1
2019 Wang LY, He YX, Li M, Ding J, Sui Y, Conaway JW, Conaway RC, Wang F, Jin J, Cai Y. DNA-dependent protein kinase catalytic subunit (DNA-PKcs) contributes to incorporation of histone variant H2A.Z into nucleosomes. Protein & Cell. PMID 31111444 DOI: 10.1007/s13238-019-0632-1  1
2019 Weems JC, Unruh JR, Slaughter BD, Conaway RC, Conaway JW. Imaging-based assays for investigating functions of the RNA polymerase II elongation factor Elongin and the Elongin ubiquitin ligase. Methods (San Diego, Calif.). PMID 30794906 DOI: 10.1016/j.ymeth.2019.02.015  1
2018 Noe Gonzalez M, Conaway RC, Conaway JW. Frozen in Transcription: Cryo-EM Structures of Pol II Transcribing through a Nucleosome. Molecular Cell. 72: 802-804. PMID 30526870 DOI: 10.1016/j.molcel.2018.11.027  1
2018 Noe Gonzalez M, Sato S, Tomomori-Sato C, Conaway JW, Conaway RC. CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts. Nature Communications. 9: 3392. PMID 30139934 DOI: 10.1038/s41467-018-05923-w  1
2018 Gopalan S, Gibbon DM, Banks CAS, Zhang Y, Florens LA, Washburn MP, Dabas P, Sharma N, Seidel CW, Conaway RC, Conaway JW. Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex. Nucleic Acids Research. PMID 30102332 DOI: 10.1093/nar/gky713  1
2017 Wu DL, Zhao LH, Feng ZT, Yu C, Ding J, Wang LY, Wang F, Liu D, Zhu HH, Xing FY, Conaway JW, Conaway RC, Cai Y, Jin JJ. O-Linked N-acetylglucosamine transferase 1 regulates global histone H4 acetylation via stabilization of the non-specific lethal protein NSL3. The Journal of Biological Chemistry. PMID 28450392 DOI: 10.1074/jbc.M117.781401  1
2017 Weems JC, Slaughter BD, Unruh JR, Boeing S, Hall SM, McLaird MB, Yasukawa T, Aso T, Svejstrup JQ, Conaway JW, Conaway RC. Cockayne Syndrome B Protein Regulates Recruitment of the Elongin A Ubiquitin Ligase to Sites of DNA Damage. The Journal of Biological Chemistry. PMID 28292928 DOI: 10.1074/jbc.C117.777946  1
2017 Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias FJ. Mediator structure and rearrangements required for holoenzyme formation. Nature. PMID 28241144 DOI: 10.1038/nature21393  1
2016 Sato S, Tomomori-Sato C, Tsai KL, Yu X, Sardiu M, Saraf A, Washburn MP, Florens L, Asturias FJ, Conaway RC, Conaway JW. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme. The Journal of Biological Chemistry. PMID 27821593 DOI: 10.1074/jbc.M116.756098  1
2016 Boeing S, Williamson L, Encheva V, Gori I, Saunders RE, Instrell R, Aygün O, Rodriguez-Martinez M, Weems JC, Kelly GP, Conaway JW, Conaway RC, Stewart A, Howell M, Snijders AP, et al. Multiomic Analysis of the UV-Induced DNA Damage Response. Cell Reports. PMID 27184836 DOI: 10.1016/j.celrep.2016.04.047  1
2015 Masuda Y, Takahashi H, Sato S, Tomomori-Sato C, Saraf A, Washburn MP, Florens L, Conaway RC, Conaway JW, Hatakeyama S. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nature Communications. 6: 7299. PMID 26095369 DOI: 10.1038/ncomms8299  1
2015 Weems JC, Slaughter BD, Unruh JR, Hall SM, McLaird MB, Gilmore JM, Washburn MP, Florens L, Yasukawa T, Aso T, Conaway JW, Conaway RC. Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses. The Journal of Biological Chemistry. 290: 15030-41. PMID 25878247 DOI: 10.1074/jbc.M114.632794  1
2015 Conaway RC, Conaway JW. Orchestrating transcription with the Pol II CTD. Nature Reviews. Molecular Cell Biology. 16: 128. PMID 25693123 DOI: 10.1038/nrm3956  1
2015 Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, Sato S, Ranjan A, Seidel CW, Tsukiyama T, Mizushima W, Hayashi M, Ohkawa Y, Conaway JW, Conaway RC, et al. MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex. Nature Communications. 6: 5941. PMID 25575120 DOI: 10.1038/ncomms6941  1
2015 Sardiu ME, Gilmore JM, Groppe BD, Herman D, Ramisetty SR, Cai Y, Jin J, Conaway RC, Conaway JW, Florens L, Washburn MP. Conserved abundance and topological features in chromatin-remodeling protein interaction networks. Embo Reports. 16: 116-26. PMID 25427557 DOI: 10.15252/embr.201439403  1
2014 Tsai KL, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Asturias FJ. Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex. Cell. 158: 463. PMID 28915369 DOI: 10.1016/j.cell.2014.06.036  1
2014 Wang L, Limbo O, Fei J, Chen L, Kim B, Luo J, Chong J, Conaway RC, Conaway JW, Ranish JA, Kadonaga JT, Russell P, Wang D. Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif. Proceedings of the National Academy of Sciences of the United States of America. 111: 18566-71. PMID 25512493 DOI: 10.1073/pnas.1420227112  1
2014 Chen L, Ooi SK, Conaway JW, Conaway RC. Biochemical assays for analyzing activities of ATP-dependent chromatin remodeling enzymes Journal of Visualized Experiments. PMID 25407555 DOI: 10.3791/51721  1
2014 Chen L, Ooi SK, Conaway RC, Conaway JW. Generation and purification of human INO80 chromatin remodeling complexes and subcomplexes Journal of Visualized Experiments. PMID 25407439 DOI: 10.3791/51720  1
2014 Tsai KL, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Asturias FJ. Subunit architecture and functional modular rearrangements of the transcriptional mediator complex. Cell. 157: 1430-44. PMID 24882805 DOI: 10.1016/j.cell.2014.05.015  1
2013 Chen L, Conaway RC, Conaway JW. Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 20497-502. PMID 24297934 DOI: 10.1073/pnas.1317092110  1
2013 Zhao X, Su J, Wang F, Liu D, Ding J, Yang Y, Conaway JW, Conaway RC, Cao L, Wu D, Wu M, Cai Y, Jin J. Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes. Plos Genetics. 9: e1003940. PMID 24244196 DOI: 10.1371/journal.pgen.1003940  1
2013 Sela D, Conkright JJ, Chen L, Gilmore J, Washburn MP, Florens L, Conaway RC, Conaway JW. Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α. The Journal of Biological Chemistry. 288: 26179-87. PMID 23864652 DOI: 10.1074/jbc.M113.496968  1
2013 Kawauchi J, Inoue M, Fukuda M, Uchida Y, Yasukawa T, Conaway RC, Conaway JW, Aso T, Kitajima S. Transcriptional properties of mammalian elongin A and its role in stress response. The Journal of Biological Chemistry. 288: 24302-15. PMID 23828199 DOI: 10.1074/jbc.M113.496703  1
2013 Tsai KL, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Asturias FJ. A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction. Nature Structural & Molecular Biology. 20: 611-9. PMID 23563140 DOI: 10.1038/nsmb.2549  1
2013 Tomomori-Sato C, Sato S, Conaway RC, Conaway JW. Immunoaffinity purification of protein complexes from mammalian cells Methods in Molecular Biology. 977: 273-287. PMID 23436370 DOI: 10.1007/978-1-62703-284-1_22  1
2013 Conaway RC, Conaway JW. The Mediator complex and transcription elongation Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms. 1829: 69-75. PMID 22983086 DOI: 10.1016/j.bbagrm.2012.08.017  1
2012 Gottschalk AJ, Trivedi RD, Conaway JW, Conaway RC. Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate. The Journal of Biological Chemistry. 287: 43527-32. PMID 23132853 DOI: 10.1074/jbc.M112.401141  1
2012 Yasukawa T, Bhatt S, Takeuchi T, Kawauchi J, Takahashi H, Tsutsui A, Muraoka T, Inoue M, Tsuda M, Kitajima S, Conaway RC, Conaway JW, Trainor PA, Aso T. Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation. Cell Reports. 2: 1129-36. PMID 23122963 DOI: 10.1016/j.celrep.2012.09.031  1
2012 Costessi A, Mahrour N, Sharma V, Stunnenberg R, Stoel MA, Tijchon E, Conaway JW, Conaway RC, Stunnenberg HG. The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. Plos One. 7: e42822. PMID 22912744 DOI: 10.1371/journal.pone.0042822  1
2012 Sela D, Chen L, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC. Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes. The Journal of Biological Chemistry. 287: 23035-45. PMID 22577136 DOI: 10.1074/jbc.M112.369504  1
2011 Costessi A, Mahrour N, Tijchon E, Stunnenberg R, Stoel MA, Jansen PW, Sela D, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC, Stunnenberg HG. The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. The Embo Journal. 30: 3786-98. PMID 21822215 DOI: 10.1038/emboj.2011.262  1
2011 Conaway RC, Conaway JW. Origins and activity of the Mediator complex Seminars in Cell and Developmental Biology. 22: 729-734. PMID 21821140 DOI: 10.1016/j.semcdb.2011.07.021  1
2011 Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, ... Conaway RC, et al. Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell. 146: 92-104. PMID 21729782 DOI: 10.1016/j.cell.2011.06.005  1
2011 Conaway RC, Conaway JW. Function and regulation of the Mediator complex Current Opinion in Genetics and Development. 21: 225-230. PMID 21330129 DOI: 10.1016/j.gde.2011.01.013  1
2011 Chen L, Cai Y, Jin J, Florens L, Swanson SK, Washburn MP, Conaway JW, Conaway RC. Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. The Journal of Biological Chemistry. 286: 11283-9. PMID 21303910 DOI: 10.1074/jbc.M111.222505  1
2011 Capotosti F, Guernier S, Lammers F, Waridel P, Cai Y, Jin J, Conaway JW, Conaway RC, Herr W. O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell. 144: 376-88. PMID 21295698 DOI: 10.1016/j.cell.2010.12.030  1
2010 Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, Shilatifard A. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular Cell. 37: 429-37. PMID 20159561 DOI: 10.1016/j.molcel.2010.01.026  1
2010 Cai Y, Jin J, Swanson SK, Cole MD, Choi SH, Florens L, Washburn MP, Conaway JW, Conaway RC. Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. The Journal of Biological Chemistry. 285: 4268-72. PMID 20018852 DOI: 10.1074/jbc.C109.087981  1
2009 Harreman M, Taschner M, Sigurdsson S, Anindya R, Reid J, Somesh B, Kong SE, Banks CAS, Conaway RC, Conaway JW, Svejstrup JQ. Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation Proceedings of the National Academy of Sciences of the United States of America. 106: 20705-20710. PMID 19920177 DOI: 10.1073/pnas.0907052106  1
2009 Takahashi H, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC. Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID. The Journal of Biological Chemistry. 284: 32405-12. PMID 19805548 DOI: 10.1074/jbc.M109.017954  1
2009 Gottschalk AJ, Timinszky G, Kong SE, Jin J, Cai Y, Swanson SK, Washburn MP, Florens L, Ladurner AG, Conaway JW, Conaway RC. Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler Proceedings of the National Academy of Sciences of the United States of America. 106: 13770-13774. PMID 19666485 DOI: 10.1073/pnas.0906920106  1
2009 Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, Svejstrup JQ. Direct inhibition of RNA polymerase II transcription by RECQL5. The Journal of Biological Chemistry. 284: 23197-203. PMID 19570979 DOI: 10.1074/jbc.M109.015750  1
2009 Conaway RC, Conaway JW. Mediator Comes Out from the Shadows Structure. 17: 485-486. PMID 19368880 DOI: 10.1016/j.str.2009.03.003  1
2009 Conaway RC, Conaway JW. The INO80 chromatin remodeling complex in transcription, replication and repair Trends in Biochemical Sciences. 34: 71-77. PMID 19062292 DOI: 10.1016/j.tibs.2008.10.010  1
2009 Ding N, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Boyer TG. MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. The Journal of Biological Chemistry. 284: 2648-56. PMID 19049968 DOI: 10.1074/jbc.M806514200  1
2008 Yasukawa T, Kamura T, Kitajima S, Conaway RC, Conaway JW, Aso T. Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1 Embo Journal. 27: 3256-3266. PMID 19037258 DOI: 10.1038/emboj.2008.249  1
2008 Yao T, Song L, Jin J, Cai Y, Takahashi H, Swanson SK, Washburn MP, Florens L, Conaway RC, Cohen RE, Conaway JW. Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Molecular Cell. 31: 909-17. PMID 18922472 DOI: 10.1016/j.molcel.2008.08.027  1
2008 Gottschalk AJ, Conaway RC, Conaway JW. New clues to actin function in chromatin regulation Nature Structural and Molecular Biology. 15: 432-433. PMID 18461045 DOI: 10.1038/nsmb0508-432  1
2008 Sardiu ME, Cai Y, Jin J, Swanson SK, Conaway RC, Conaway JW, Florens L, Washburn MP. Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics. Proceedings of the National Academy of Sciences of the United States of America. 105: 1454-9. PMID 18218781 DOI: 10.1073/pnas.0706983105  1
2008 Mahrour N, Redwine WB, Florens L, Swanson SK, Martin-Brown S, Bradford WD, Staehling-Hampton K, Washburn MP, Conaway RC, Conaway JW. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. The Journal of Biological Chemistry. 283: 8005-13. PMID 18187417 DOI: 10.1074/jbc.M706987200  1
2008 Koutelou E, Sato S, Tomomori-Sato C, Florens L, Swanson SK, Washburn MP, Kokkinaki M, Conaway RC, Conaway JW, Moschonas NK. Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. The Journal of Biological Chemistry. 283: 3846-53. PMID 18077452 DOI: 10.1074/jbc.M706974200  1
2007 Cai Y, Jin J, Yao T, Gottschalk AJ, Swanson SK, Wu S, Shi Y, Washburn MP, Florens L, Conaway RC, Conaway JW. YY1 functions with INO80 to activate transcription. Nature Structural & Molecular Biology. 14: 872-4. PMID 17721549 DOI: 10.1038/nsmb1276  1
2007 Banks CA, Kong SE, Spahr H, Florens L, Martin-Brown S, Washburn MP, Conaway JW, Mushegian A, Conaway RC. Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. The Journal of Biological Chemistry. 282: 5761-9. PMID 17150956 DOI: 10.1074/jbc.M610393200  1
2006 Svejstrup JQ, Conaway RC, Conaway JW. RNA Polymerase II: A "Nobel" Enzyme Demystified Molecular Cell. 24: 637-642. PMID 17157247 DOI: 10.1016/j.molcel.2006.11.016  1
2006 Paoletti AC, Parmely TJ, Tomomori-Sato C, Sato S, Zhu D, Conaway RC, Conaway JW, Florens L, Washburn MP. Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors. Proceedings of the National Academy of Sciences of the United States of America. 103: 18928-33. PMID 17138671 DOI: 10.1073/pnas.0606379103  1
2006 Cai Y, Jin J, Gottschalk AJ, Yao T, Conaway JW, Conaway RC. Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes Methods. 40: 312-317. PMID 17101442 DOI: 10.1016/j.ymeth.2006.06.023  1
2006 Yao T, Song L, Xu W, DeMartino GN, Florens L, Swanson SK, Washburn MP, Conaway RC, Conaway JW, Cohen RE. Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. Nature Cell Biology. 8: 994-1002. PMID 16906146 DOI: 10.1038/ncb1460  1
2006 Ruhl DD, Jin J, Cai Y, Swanson S, Florens L, Washburn MP, Conaway RC, Conaway JW, Chrivia JC. Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes. Biochemistry. 45: 5671-7. PMID 16634648 DOI: 10.1021/bi060043d  1
2005 Jin J, Cai Y, Li B, Conaway RC, Workman JL, Conaway JW, Kusch T. In and out: histone variant exchange in chromatin. Trends in Biochemical Sciences. 30: 680-7. PMID 16257529 DOI: 10.1016/j.tibs.2005.10.003  1
2005 Jin J, Cai Y, Yao T, Gottschalk AJ, Florens L, Swanson SK, Gutiérrez JL, Coleman MK, Workman JL, Mushegian A, Washburn MP, Conaway RC, Conaway JW. A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. The Journal of Biological Chemistry. 280: 41207-12. PMID 16230350 DOI: 10.1074/jbc.M509128200  1
2005 Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC. ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America. 102: 10094-8. PMID 16006523 DOI: 10.1073/pnas.0503017102  1
2005 Conaway RC, Sato S, Tomomori-Sato C, Yao T, Conaway JW. The mammalian Mediator complex and its role in transcriptional regulation Trends in Biochemical Sciences. 30: 250-255. PMID 15896743 DOI: 10.1016/j.tibs.2005.03.002  1
2005 Conaway JW, Florens L, Sato S, Tomomori-Sato C, Parmely TJ, Yao T, Swanson SK, Banks CA, Washburn MP, Conaway RC. The mammalian Mediator complex. Febs Letters. 579: 904-8. PMID 15680972 DOI: 10.1016/j.febslet.2004.11.031  1
2005 Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW. The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. The Journal of Biological Chemistry. 280: 13665-70. PMID 15647280 DOI: 10.1074/jbc.M500001200  1
2005 Gerber M, Tenney K, Conaway JW, Conaway RC, Eissenberg JC, Shilatifard A. Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. The Journal of Biological Chemistry. 280: 4017-20. PMID 15611125 DOI: 10.1074/jbc.C400487200  1
2005 Heuzé ML, Guibal FC, Banks CA, Conaway JW, Conaway RC, Cayre YE, Benecke A, Lutz PG. ASB2 is an elongin BC-interacting protein that can assemble with cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex Journal of Biological Chemistry. 280: 5468-5474. PMID 15590664 DOI: 10.1074/jbc.M413040200  1
2004 Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases Genes and Development. 18: 3055-3065. PMID 15601820 DOI: 10.1101/gad.1252404  1
2004 Gerber M, Eissenberg JC, Kong S, Tenney K, Conaway JW, Conaway RC, Shilatifard A. In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Molecular and Cellular Biology. 24: 9911-9. PMID 15509793 DOI: 10.1128/MCB.24.22.9911-9919.2004  1
2004 Blanchette P, Cheng CY, Yan Q, Ketner G, Ornelles DA, Dobner T, Conaway RC, Conaway JW, Branton PE. Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. Molecular and Cellular Biology. 24: 9619-29. PMID 15485928 DOI: 10.1128/MCB.24.21.9619-9629.2004  1
2004 Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW. Identification of Elongin C and Skp1 sequences that determine Cullin selection. The Journal of Biological Chemistry. 279: 43019-26. PMID 15280393 DOI: 10.1074/jbc.M408018200  1
2004 Sato S, Tomomori-Sato C, Parmely TJ, Florens L, Zybailov B, Swanson SK, Banks CA, Jin J, Cai Y, Washburn MP, Conaway JW, Conaway RC. A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Molecular Cell. 14: 685-91. PMID 15175163 DOI: 10.1016/j.molcel.2004.05.006  1
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/j.molcel.2004.05.011  1
2004 Tomomori-Sato C, Sato S, Parmely TJ, Banks CA, Sorokina I, Florens L, Zybailov B, Washburn MP, Brower CS, Conaway RC, Conaway JW. A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2. The Journal of Biological Chemistry. 279: 5846-51. PMID 14638676 DOI: 10.1074/jbc.M312523200  1
2003 Kong SE, Shilatifard A, Conaway RC, Conaway JW. Preparation and Assay of RNA Polymerase II Elongation Factors Elongin and ELL Methods in Enzymology. 371: 276-283. PMID 14712707 DOI: 10.1016/S0076-6879(03)71020-9  1
2003 Dvir A, Conaway JW, Conaway RC. Assays for Investigating the Mechanism of Promoter Escape by RNA Polymerase II Methods in Enzymology. 370: 733-740. PMID 14712687 DOI: 10.1016/S0076-6879(03)70059-7  1
2003 Sato S, Tomomori-Sato C, Banks CA, Parmely TJ, Sorokina I, Brower CS, Conaway RC, Conaway JW. A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex. The Journal of Biological Chemistry. 278: 49671-4. PMID 14576168 DOI: 10.1074/jbc.C300444200  1
2003 Cai Y, Jin J, Tomomori-Sato C, Sato S, Sorokina I, Parmely TJ, Conaway RC, Conaway JW. Identification of New Subunits of the Multiprotein Mammalian TRRAP/TIP60-containing Histone Acetyltransferase Complex Journal of Biological Chemistry. 278: 42733-42736. PMID 12963728 DOI: 10.1074/jbc.C300389200  1
2003 Conaway RC, Kong SE, Conaway JW. TFIIS and GreB: Two like-minded transcription elongation factors with sticky fingers Cell. 114: 272-274. PMID 12914690 DOI: 10.1016/S0092-8674(03)00607-X  1
2003 Shilatifard A, Conaway RC, Conaway JW. The RNA polymerase II elongation complex. Annual Review of Biochemistry. 72: 693-715. PMID 12676794 DOI: 10.1146/annurev.biochem.72.121801.161551  1
2003 Kuznetsova AV, Meller J, Schnell PO, Nash JA, Ignacak ML, Sanchez Y, Conaway JW, Conaway RC, Czyzyk-Krzeska MF. von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 100: 2706-11. PMID 12604794 DOI: 10.1073/pnas.0436037100  1
2003 Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE, Jin J, Cai Y, Lane WS, Brower CS, Conaway RC, Conaway JW. Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. The Journal of Biological Chemistry. 278: 15123-7. PMID 12584197 DOI: 10.1074/jbc.C300054200  1
2003 Maynard MA, Qi H, Chung J, Lee EH, Kondo Y, Hara S, Conaway RC, Conaway JW, Ohh M. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. The Journal of Biological Chemistry. 278: 11032-40. PMID 12538644 DOI: 10.1074/jbc.M208681200  1
2002 Conaway RC, Conaway JW. The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription Advances in Cancer Research. 85: 1-12. PMID 12374282 DOI: 10.1016/S0065-230X(02)85001-1  1
2002 Ivan M, Haberberger T, Gervasi DC, Michelson KS, Günzler V, Kondo K, Yang H, Sorokina I, Conaway RC, Conaway JW, Kaelin WG. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proceedings of the National Academy of Sciences of the United States of America. 99: 13459-64. PMID 12351678 DOI: 10.1073/pnas.192342099  1
2002 Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 99: 10353-8. PMID 12149480 DOI: 10.1073/pnas.162424199  1
2002 Kamura T, Brower CS, Conaway RC, Conaway JW. A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase Journal of Biological Chemistry. 277: 30388-30393. PMID 12048197  1
2002 Conaway RC, Brower CS, Conaway JW. Emerging roles of ubiquitin in transcription regulation Science. 296: 1254-1258. PMID 12016299 DOI: 10.1126/science.1067466  1
2002 Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex Nature. 416: 703-709. PMID 11961546 DOI: 10.1038/416703a  1
2002 Kamura T, Conaway JW, Conaway RC. Roles of SCF and VHL ubiquitin ligases in regulation of cell growth Progress in Molecular and Subcellular Biology. 29: 1-15. PMID 11908068  1
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