| Year |
Citation |
Score |
| 2022 |
Isaac R, Vinik Y, Mikl M, Nadav-Eliyahu S, Shatz-Azoulay H, Yaakobi A, DeForest N, Majithia AR, Webster NJG, Shav-Tal Y, Elhanany E, Zick Y. A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing. Iscience. 25: 105270. PMID 36304109 DOI: 10.1016/j.isci.2022.105270 |
0.72 |
|
| 2022 |
Cao M, Isaac R, Yan W, Ruan X, Jiang L, Wan Y, Wang J, Wang E, Caron C, Neben S, Drygin D, Pizzo DP, Wu X, Liu X, Chin AR, et al. Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth. Nature Cell Biology. PMID 35637408 DOI: 10.1038/s41556-022-00919-7 |
0.323 |
|
| 2022 |
Moon JS, Riopel M, Seo JB, Herrero-Aguayo V, Isaac R, Lee YS. HIF-2α Preserves Mitochondrial Activity And Glucose Sensing in Compensating Beta Cells in Obesity. Diabetes. PMID 35472707 DOI: 10.2337/db21-0736 |
0.325 |
|
| 2020 |
Shatz-Azoulay H, Vinik Y, Isaac R, Kohler U, Lev S, Zick Y. The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice. Scientific Reports. 10: 7375. PMID 32355198 DOI: 10.1038/S41598-020-64371-Z |
0.724 |
|
| 2019 |
El Ouarrat D, Isaac R, Lee YS, Oh DY, Wollam J, Lackey D, Riopel M, Bandyopadhyay G, Seo JB, Sampath-Kumar R, Olefsky JM. TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance. Cell Metabolism. PMID 31708444 DOI: 10.1016/J.Cmet.2019.10.003 |
0.353 |
|
| 2019 |
Lackey DE, Reis FCG, Isaac R, Zapata RC, El Ouarrat D, Lee YS, Bandyopadhyay G, Ofrecio JM, Oh DY, Osborn O. Adipocyte PU.1 knockout promotes insulin sensitivity in HFD-fed obese mice. Scientific Reports. 9: 14779. PMID 31611602 DOI: 10.1038/s41598-019-51196-8 |
0.34 |
|
| 2018 |
Ying W, Lee YS, Dong Y, Seidman JS, Yang M, Isaac R, Seo JB, Yang BH, Wollam J, Riopel M, McNelis J, Glass CK, Olefsky JM, Fu W. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity. Cell Metabolism. PMID 30595478 DOI: 10.1016/J.Cmet.2018.12.003 |
0.352 |
|
| 2018 |
Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y. Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells. The Journal of Biological Chemistry. 293: 4577-4578. PMID 29572328 DOI: 10.1074/jbc.AAC118.002476 |
0.655 |
|
| 2017 |
Isaac R, Vinik Y, Boura-Halfon S, Farack L, Streim S, Elhanany E, Kam Z, Zick Y. Prolonged Elimination of Negative Feedback Control Mechanisms Along the Insulin Signalling Pathway Impairs β Cell Function In Vivo. Diabetes. PMID 28424159 DOI: 10.2337/Db16-0827 |
0.75 |
|
| 2016 |
Isaac R, Goldstein I, Furth N, Zilber N, Streim S, Boura-Halfon S, Elhanany E, Rotter V, Oren M, Zick Y. TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response. Cell Death and Differentiation. PMID 27740623 DOI: 10.1038/Cdd.2016.108 |
0.675 |
|
| 2016 |
Bucris E, Beck A, Boura-Halfon S, Isaac R, Vinik Y, Rosenzweig T, Sampson S, Zick Y. Prolonged insulin treatment sensitizes apoptosis pathways in pancreatic beta cells. The Journal of Endocrinology. PMID 27411561 DOI: 10.1530/Joe-15-0505 |
0.759 |
|
| 2015 |
Beck A, Shatz-Azoulay H, Vinik Y, Isaac R, Boura-Halfon S, Zick Y. Nedd4 family interacting protein 1 (Ndfip1) promotes death of pancreatic beta cells. Biochemical and Biophysical Research Communications. 465: 851-6. PMID 26319551 DOI: 10.1016/J.Bbrc.2015.08.099 |
0.765 |
|
| 2013 |
Beck A, Vinik Y, Shatz-Azoulay H, Isaac R, Streim S, Jona G, Boura-Halfon S, Zick Y. Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets. Diabetologia. 56: 1317-26. PMID 23515685 DOI: 10.1007/S00125-013-2889-X |
0.739 |
|
| 2013 |
Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y. Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells. The Journal of Biological Chemistry. 288: 5682-93. PMID 23275337 DOI: 10.1074/Jbc.M112.408641 |
0.717 |
|
| 2011 |
Beck A, Isaac R, Lavelin I, Hart Y, Volberg T, Shatz-Azoulay H, Geiger B, Zick Y. An siRNA screen identifies transmembrane 7 superfamily member 3 (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of cytokine-induced death of pancreatic beta cells. Diabetologia. 54: 2845-55. PMID 21853325 DOI: 10.1007/S00125-011-2277-3 |
0.747 |
|
| 2010 |
Gurevitch D, Boura-Halfon S, Isaac R, Shahaf G, Alberstein M, Ronen D, Lewis EC, Zick Y. Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress. Diabetes. 59: 2188-97. PMID 20547979 DOI: 10.2337/Db09-0890 |
0.71 |
|
| 2007 |
Levkovitz Y, Ben-Shushan G, Hershkovitz A, Isaac R, Gil-Ad I, Shvartsman D, Ronen D, Weizman A, Zick Y. Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases. Molecular and Cellular Neurosciences. 36: 305-12. PMID 17728140 DOI: 10.1016/J.Mcn.2007.05.009 |
0.651 |
|
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