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David R Gius - Publications

Affiliations: 
Northwestern University Feinberg School of Medicine, Chicago, IL, United States 
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kosciuczuk EM, Mehrotra S, Saleiro D, Kroczynska B, Majchrzak-Kita B, Lisowski P, Driehaus C, Rogalska A, Turner A, Lienhoop T, Gius D, Fish EN, Vassilopoulos A, Platanias LC. Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses. The Journal of Biological Chemistry. PMID 30487288 DOI: 10.1074/Jbc.Ra118.005956  0.43
2018 Song HY, Rellinger EJ, Park SH, Paul P, Qiao J, Vasilopoulos A, Ozden O, Gius D, Chung DH. Inhibition of Sirtuin 6 Induces Neuroblastoma Differentiation. Anticancer Research. 38: 647-654. PMID 29374686 DOI: 10.21873/Anticanres.12268  0.301
2017 Traba J, Geiger SS, Kwarteng Siaw M, Han K, Ra OH, Siegel RM, Gius D, Sack MN. Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3 mediated activation of Superoxide Dismutase 2. The Journal of Biological Chemistry. PMID 28584055 DOI: 10.1074/jbc.M117.791715  0.351
2016 Vidimar V, Gius D, Chakravarti D, Bulun SE, Wei JJ, Kim JJ. Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. Science Advances. 2: e1601132. PMID 27847869 DOI: 10.1126/Sciadv.1601132  0.405
2016 Song HY, Biancucci M, Kang HJ, O'Callaghan C, Park SH, Principe DR, Jiang H, Yan Y, Satchell KF, Raparia K, Gius D, Vassilopoulos A. SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status. Oncotarget. PMID 27637077 DOI: 10.18632/oncotarget.12015  0.309
2016 Zhang H, Head PE, Daddacha W, Park SH, Li X, Pan Y, Madden MZ, Duong DM, Xie M, Yu B, Warren MD, Liu EA, Dhere VR, Li C, Pradilla I, ... ... Gius D, et al. ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. Cell Reports. PMID 26854234 DOI: 10.1016/J.Celrep.2016.01.018  0.338
2015 Agarwal S, Zhu Y, Gius DR, Satchell KJ. Makes Caterpillars Floppy (MCFVv)-like domain of Vibrio vulnificus induces mitochondrial-mediated apoptosis. Infection and Immunity. PMID 26351282 DOI: 10.1128/IAI.00570-15  0.311
2015 Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, Zou JX, Zhang T, Juma S, Jin C, Li RF, Perks J, Sun LQ, Vaughan AT, Hai CX, ... Gius DR, et al. CDK1-mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Molecular Cancer Therapeutics. PMID 26141949 DOI: 10.1158/1535-7163.MCT-15-0017  0.353
2015 Pillai VB, Samant S, Sundaresan NR, Raghuraman H, Kim G, Bonner MY, Arbiser JL, Walker DI, Jones DP, Gius D, Gupta MP. Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3. Nature Communications. 6: 6656. PMID 25871545 DOI: 10.1038/Ncomms7656  0.323
2014 Ozden O, Park SH, Wagner BA, Yong Song H, Zhu Y, Vassilopoulos A, Jung B, Buettner GR, Gius D. SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. Free Radical Biology & Medicine. 76: 163-72. PMID 25152236 DOI: 10.1016/J.Freeradbiomed.2014.08.001  0.309
2014 Tao R, Vassilopoulos A, Parisiadou L, Yan Y, Gius D. Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis. Antioxidants & Redox Signaling. 20: 1646-54. PMID 23886445 DOI: 10.1089/Ars.2013.5482  0.332
2013 Zhang H, Park SH, Pantazides BG, Karpiuk O, Warren MD, Hardy CW, Duong DM, Park SJ, Kim HS, Vassilopoulos A, Seyfried NT, Johnsen SA, Gius D, Yu DS. SIRT2 directs the replication stress response through CDK9 deacetylation. Proceedings of the National Academy of Sciences of the United States of America. 110: 13546-51. PMID 23898190 DOI: 10.1073/Pnas.1301463110  0.311
2013 Liang Q, Benavides GA, Vassilopoulos A, Gius D, Darley-Usmar V, Zhang J. Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts. The Biochemical Journal. 454: 249-57. PMID 23767918 DOI: 10.1042/Bj20130414  0.325
2012 Zhu Y, Park SH, Ozden O, Kim HS, Jiang H, Vassilopoulos A, Spitz DR, Gius D. Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity. Free Radical Biology & Medicine. 53: 828-33. PMID 22732184 DOI: 10.1016/J.Freeradbiomed.2012.06.020  0.303
2010 Tao R, Coleman MC, Pennington JD, Ozden O, Park SH, Jiang H, Kim HS, Flynn CR, Hill S, Hayes McDonald W, Olivier AK, Spitz DR, Gius D. Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Molecular Cell. 40: 893-904. PMID 21172655 DOI: 10.1016/J.Molcel.2010.12.013  0.35
2009 Kassis JN, Virador VM, Guancial EA, Kimm D, Ho AS, Mishra M, Chuang EY, Cook J, Gius D, Kohn EC. Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3-modulated adhesion and invasion. The Journal of Pathology. 218: 495-504. PMID 19402132 DOI: 10.1002/path.2557  0.363
2008 Jacobs KM, Pennington JD, Bisht KS, Aykin-Burns N, Kim HS, Mishra M, Sun L, Nguyen P, Ahn BH, Leclerc J, Deng CX, Spitz DR, Gius D. SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. International Journal of Biological Sciences. 4: 291-9. PMID 18781224 DOI: 10.7150/Ijbs.4.291  0.391
2008 Mishra MV, Bisht KS, Sun L, Muldoon-Jacobs K, Awwad R, Kaushal A, Nguyen P, Huang L, Pennington JD, Markovina S, Bradbury CM, Gius D. DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells. Molecular Cancer Research : McR. 6: 243-9. PMID 18314485 DOI: 10.1158/1541-7786.Mcr-07-0373  0.314
2007 Pennington JD, Jacobs KM, Sun L, Bar-Sela G, Mishra M, Gius D. Thioredoxin and thioredoxin reductase as redox-sensitive molecular targets for cancer therapy. Current Pharmaceutical Design. 13: 3368-77. PMID 18045191 DOI: 10.2174/138161207782360528  0.384
2006 Gius D, Spitz DR. Redox signaling in cancer biology. Antioxidants & Redox Signaling. 8: 1249-52. PMID 16910772 DOI: 10.1089/Ars.2006.8.1249  0.343
2006 Nguyen P, Awwad RT, Smart DD, Spitz DR, Gius D. Thioredoxin reductase as a novel molecular target for cancer therapy. Cancer Letters. 236: 164-74. PMID 15955621 DOI: 10.1016/J.Canlet.2005.04.028  0.367
2005 Pennington JD, Wang TJ, Nguyen P, Sun L, Bisht K, Smart D, Gius D. Redox-sensitive signaling factors as a novel molecular targets for cancer therapy. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 8: 322-30. PMID 16230045 DOI: 10.1016/j.drup.2005.09.002  0.375
2005 Wang T, Hu YC, Dong S, Fan M, Tamae D, Ozeki M, Gao Q, Gius D, Li JJ. Co-activation of ERK, NF-kappaB, and GADD45beta in response to ionizing radiation. The Journal of Biological Chemistry. 280: 12593-601. PMID 15642734 DOI: 10.1074/Jbc.M410982200  0.448
2004 Smart DK, Ortiz KL, Mattson D, Bradbury CM, Bisht KS, Sieck LK, Brechbiel MW, Gius D. Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress. Cancer Research. 64: 6716-24. PMID 15374989 DOI: 10.1158/0008-5472.CAN-03-3990  0.449
2004 Cook JA, Gius D, Wink DA, Krishna MC, Russo A, Mitchell JB. Oxidative stress, redox, and the tumor microenvironment. Seminars in Radiation Oncology. 14: 259-66. PMID 15254869 DOI: 10.1016/J.Semradonc.2004.04.001  0.314
2004 Spitz DR, Azzam EI, Li JJ, Gius D. Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology. Cancer Metastasis Reviews. 23: 311-22. PMID 15197331 DOI: 10.1023/B:Canc.0000031769.14728.Bc  0.349
2004 Mimnaugh EG, Xu W, Vos M, Yuan X, Isaacs JS, Bisht KS, Gius D, Neckers L. Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity. Molecular Cancer Therapeutics. 3: 551-66. PMID 15141013  0.363
2004 Lagunas L, Bradbury CM, Laszlo A, Hunt CR, Gius D. Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells. Biochemical and Biophysical Research Communications. 313: 863-70. PMID 14706622 DOI: 10.1016/j.bbrc.2003.12.018  0.467
2003 Bisht KS, Bradbury CM, Mattson D, Kaushal A, Sowers A, Markovina S, Ortiz KL, Sieck LK, Isaacs JS, Brechbiel MW, Mitchell JB, Neckers LM, Gius D. Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity. Cancer Research. 63: 8984-95. PMID 14695217  0.46
2003 Ohiro Y, Usheva A, Kobayashi S, Duffy SL, Nantz R, Gius D, Horikoshi N. Inhibition of stress-inducible kinase pathways by tumorigenic mutant p53. Molecular and Cellular Biology. 23: 322-34. PMID 12482984  0.323
2002 Karimpour S, Lou J, Lin LL, Rene LM, Lagunas L, Ma X, Karra S, Bradbury CM, Markovina S, Goswami PC, Spitz DR, Hirota K, Kalvakolanu DV, Yodoi J, Gius D. Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation. Oncogene. 21: 6317-27. PMID 12214272 DOI: 10.1038/Sj.Onc.1205749  0.468
2002 Ohiro Y, Garkavtsev I, Kobayashi S, Sreekumar KR, Nantz R, Higashikubo BT, Duffy SL, Higashikubo R, Usheva A, Gius D, Kley N, Horikoshi N. A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF). Febs Letters. 524: 163-71. PMID 12135761 DOI: 10.1016/S0014-5793(02)03049-1  0.392
2002 Sekhar KR, Spitz DR, Harris S, Nguyen TT, Meredith MJ, Holt JT, Gius D, Marnett LJ, Summar ML, Freeman ML, Guis D. Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase. Free Radical Biology & Medicine. 32: 650-62. PMID 11909699 DOI: 10.1016/S0891-5849(02)00755-4  0.436
2002 Zoberi I, Bradbury CM, Curry HA, Bisht KS, Goswami PC, Roti Roti JL, Gius D. Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines. Cancer Letters. 175: 165-73. PMID 11741744 DOI: 10.1016/S0304-3835(01)00719-4  0.302
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