Amy Ramsey - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Website:
https://www.pharmtox.utoronto.ca/faculty-amy-j-ramsey-phd

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang X, Marmouzi I, Finnie PS, Støve SI, Bucher ML, Lipina TV, Ramsey AJ, Miller GW, Salahpour A. Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants. Biorxiv : the Preprint Server For Biology. PMID 37873339 DOI: 10.1101/2023.10.09.561601  0.483
2023 Venkatesan S, Binko MA, Mielnik CA, Ramsey AJ, Lambe EK. Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37349472 DOI: 10.1038/s41386-023-01619-y  0.672
2023 Russo EE, Zovko LE, Nazari R, Steenland H, Ramsey AJ, Salahpour A. Evaluation and Validation of Commercially Available Dopamine Transporter Antibodies. Eneuro. 10. PMID 37142435 DOI: 10.1523/ENEURO.0341-22.2023  0.629
2022 Mielnik CA, Li CK, Ramsey AJ, Salahpour A, Burnham WM, Ross RA. Cannabidiol, but Not Δ9-Tetrahydrocannabinol, Has Strain- and Genotype-Specific Effects in Models of Psychosis. Cannabis and Cannabinoid Research. PMID 36251462 DOI: 10.1089/can.2022.0125  0.66
2022 Lipina T, Men X, Blundell M, Salahpour A, Ramsey AJ. Abnormal sensory perception masks behavioral performance of Grin1 knockdown mice. Genes, Brain, and Behavior. e12825. PMID 35705513 DOI: 10.1111/gbb.12825  0.669
2022 Sutton C, Williams EQ, Homsi H, Beerepoot P, Nazari R, Han D, Ramsey AJ, Mash DC, Olson DE, Blough B, Salahpour A. Structure-Activity Relationships of Dopamine Transporter Pharmacological Chaperones. Frontiers in Cellular Neuroscience. 16: 832536. PMID 35614973 DOI: 10.3389/fncel.2022.832536  0.646
2021 Vecchio LM, Sullivan P, Dunn AR, Bermejo MK, Fu R, Masoud ST, Gregersen E, Urs NM, Nazari R, Jensen PH, Ramsey A, Goldstein DS, Miller GW, Salahpour A. Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo. Journal of Neurochemistry. PMID 33991113 DOI: 10.1111/jnc.15432  0.711
2020 Mielnik CA, Sugamori KS, Finlay DB, Thorpe HHA, Schapira M, Sivananthan N, Li CK, Lam VM, Harrington S, Abdelrahman MH, Trembleau LA, McIntyre Burnham W, Khokhar JY, Salahpour A, Ramsey AJ, et al. A novel allosteric modulator of the cannabinoid CB receptor ameliorates hyperdopaminergia endophenotypes in rodent models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33036015 DOI: 10.1038/s41386-020-00876-5  0.692
2020 Mielnik CA, Binko MA, Chen Y, Funk AJ, Johansson EM, Intson K, Sivananthan N, Islam R, Milenkovic M, Horsfall W, Ross RA, Groc L, Salahpour A, McCullumsmith RE, Tripathy S, ... ... Ramsey AJ, et al. Consequences of NMDA receptor deficiency can be rescued in the adult brain. Molecular Psychiatry. PMID 32807843 DOI: 10.1038/S41380-020-00859-4  0.749
2020 Oliver DK, Intson K, Sargin D, Power SK, McNabb J, Ramsey AJ, Lambe EK. Chronic social isolation exerts opposing sex-specific consequences on serotonin neuronal excitability and behaviour. Neuropharmacology. 108015. PMID 32092443 DOI: 10.1016/j.neuropharm.2020.108015  0.599
2020 McCullumsmith R, Alganem K, Henkel N, Hammoud A, Shukla R, Ramsey A, Wu W, Meller J. S183. ABNORMALITIES IN SERINE/THREONINE SIGNALING NETWORKS IN SEVERE NEUROPSYCHIATRIC ILLNESS: DEVELOPMENT OF A PIPELINE TO EXPLORE ABNORMALITIES OF KINASE ACTIVITY AND IDENTIFY NOVEL TREATMENT STRATEGIES FOR SCHIZOPHRENIA Schizophrenia Bulletin. 46: S107-S108. DOI: 10.1093/Schbul/Sbaa031.249  0.312
2019 Intson K, van Eede MC, Islam R, Milenkovic M, Yan Y, Salahpour A, Henkelman RM, Ramsey AJ. Progressive neuroanatomical changes caused by Grin1 loss-of-function mutation. Neurobiology of Disease. 104527. PMID 31299220 DOI: 10.1016/J.Nbd.2019.104527  0.665
2019 Ramsey A. 21.1 ADULT RESCUE OF NMDA RECEPTORS IMPROVES COGNITION AND ASTROCYTIC GENE EXPRESSION PATTERNS Schizophrenia Bulletin. 45: S123-S124. DOI: 10.1093/Schbul/Sbz022.085  0.346
2018 Chen Y, Milenkovic M, Horsfall W, Salahpour A, Soderling SH, Ramsey AJ. Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice. Plos One. 13: e0199341. PMID 30352064 DOI: 10.1371/Journal.Pone.0199341  0.751
2018 Lam VM, Mielnik CA, Baimel C, Beerepoot P, Espinoza S, Sukhanov I, Horsfall W, Gainetdinov RR, Borgland SL, Ramsey AJ, Salahpour A. Behavioral Effects of a Potential Novel TAAR1 Antagonist. Frontiers in Pharmacology. 9: 953. PMID 30233365 DOI: 10.3389/Fphar.2018.00953  0.664
2018 Sullivan CR, Koene RH, Hasselfeld K, O'Donovan SM, Ramsey A, McCullumsmith RE. Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia. Molecular Psychiatry. PMID 29497148 DOI: 10.1038/S41380-018-0035-3  0.314
2018 Funk A, Mielnik C, O’Donovan S, Sullivan C, Chen Y, McCullumsmith R, Ramsey A. 12.2 METABOLIC CONSEQUENCES OF DEVELOPMENTAL NMDA RECEPTOR HYPOFUNCTION Schizophrenia Bulletin. 44: S19-S20. DOI: 10.1093/Schbul/Sby014.045  0.331
2017 Sullivan CR, O'Donovan SM, McCullumsmith RE, Ramsey A. Defects in Bioenergetic Coupling in Schizophrenia. Biological Psychiatry. PMID 29217297 DOI: 10.1016/J.Biopsych.2017.10.014  0.339
2017 Islam R, Trépanier MO, Milenkovic M, Horsfall W, Salahpour A, Bazinet RP, Ramsey AJ. Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction. Npj Schizophrenia. 3: 12. PMID 28560258 DOI: 10.1038/s41537-017-0014-8  0.665
2017 Sullivan C, O’Donovan S, Ramsey A, McCullumsmith R. 176.1 Bioenergetic Uncoupling of Astrocytes and Neurons May Underlie Cognitive Deficits in Schizophrenia Schizophrenia Bulletin. 43: S90-S91. DOI: 10.1093/Schbul/Sbx021.243  0.301
2016 Grannan MD, Mielnik CA, Moran S, Gould RW, Ball JR, Lu Z, Bubser M, Ramsey AJ, Abe M, Cho HP, Nance KD, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW, et al. Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction are Reversed by the Novel M1 PAM VU6004256. Acs Chemical Neuroscience. PMID 27617634 DOI: 10.1021/Acschemneuro.6B00230  0.368
2015 Ruddy RM, Chen Y, Milenkovic M, Ramsey AJ. Differential effects of NMDA receptor antagonism on spine density Synapse. 69: 52-56. PMID 25220437 DOI: 10.1002/syn.21784  0.658
2014 Milenkovic M, Mielnik CA, Ramsey AJ. NMDA receptor-deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities Genes, Brain and Behavior. 13: 850-862. PMID 25327402 DOI: 10.1111/gbb.12183  0.355
2014 Bermejo MK, Milenkovic M, Salahpour A, Ramsey AJ. Preparation of synaptic plasma membrane and postsynaptic density proteins using a discontinuous sucrose gradient. Journal of Visualized Experiments : Jove. e51896. PMID 25226023 DOI: 10.3791/51896  0.597
2014 Vecchio LM, Bermejo MK, Beerepoot P, Ramsey AJ, Salahpour A. N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo. Molecular and Cellular Neurosciences. 61: 123-32. PMID 24886986 DOI: 10.1016/J.Mcn.2014.05.007  0.687
2014 Ferris MJ, Milenkovic M, Liu S, Mielnik CA, Beerepoot P, John CE, España RA, Sotnikova TD, Gainetdinov RR, Borgland SL, Jones SR, Ramsey AJ. Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling. The European Journal of Neuroscience. 40: 2255-63. PMID 24754704 DOI: 10.1111/Ejn.12594  0.523
2013 Medvedev IO, Ramsey AJ, Masoud ST, Bermejo MK, Urs N, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Salahpour A. D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18125-33. PMID 24227722 DOI: 10.1523/Jneurosci.2382-13.2013  0.743
2013 Gregory KJ, Herman EJ, Ramsey AJ, Hammond AS, Byun NE, Stauffer SR, Manka JT, Jadhav S, Bridges TM, Weaver CD, Niswender CM, Steckler T, Drinkenburg WH, Ahnaou A, Lavreysen H, et al. N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement. The Journal of Pharmacology and Experimental Therapeutics. 347: 438-57. PMID 23965381 DOI: 10.1124/Jpet.113.206623  0.73
2013 Siesser WB, Sachs BD, Ramsey AJ, Sotnikova TD, Beaulieu JM, Zhang X, Caron MG, Gainetdinov RR. Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. Acs Chemical Neuroscience. 4: 84-8. PMID 23336047 DOI: 10.1021/cn300127h  0.571
2011 Jocoy EL, André VM, Cummings DM, Rao SP, Wu N, Ramsey AJ, Caron MG, Cepeda C, Levine MS. Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum. Frontiers in Systems Neuroscience. 5: 28. PMID 21617735 DOI: 10.3389/Fnsys.2011.00028  0.511
2011 Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/Pnas.1012621108  0.714
2010 Gaisler-Salomon I, Wang Y, McKinney SM, Ramsey AJ, Sibille E, Rayport S. ADULT-ONSET GLUTAMATE RECEPTOR EXPRESSION DEFICITS IN THE HIPPOCAMPUS OF GLUTAMINASE-DEFICIENT MICE Schizophrenia Research. 117: 389. DOI: 10.1016/j.schres.2010.02.701  0.334
2009 Ramsey AJ. NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia. Progress in Brain Research. 179: 51-8. PMID 20302817 DOI: 10.1016/S0079-6123(09)17906-2  0.342
2009 Dzirasa K, Ramsey AJ, Takahashi DY, Stapleton J, Potes JM, Williams JK, Gainetdinov RR, Sameshima K, Caron MG, Nicolelis MA. Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8215-24. PMID 19553461 DOI: 10.1523/Jneurosci.1773-09.2009  0.54
2009 Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 106: 3507-12. PMID 19196972 DOI: 10.1073/Pnas.0805854106  0.475
2009 Ghisi V, Ramsey AJ, Masri B, Gainetdinov RR, Caron MG, Salahpour A. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. Cellular Signalling. 21: 87-94. PMID 18929645 DOI: 10.1016/J.Cellsig.2008.09.011  0.738
2008 Barak LS, Salahpour A, Zhang X, Masri B, Sotnikova TD, Ramsey AJ, Violin JD, Lefkowitz RJ, Caron MG, Gainetdinov RR. Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor. Molecular Pharmacology. 74: 585-94. PMID 18524885 DOI: 10.1124/Mol.108.048884  0.703
2008 Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 105: 4405-10. PMID 18347339 DOI: 10.1073/Pnas.0707646105  0.761
2008 Ramsey AJ, Laakso A, Cyr M, Sotnikova TD, Salahpour A, Medvedev IO, Dykstra LA, Gainetdinov RR, Caron MG. Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2701-14. PMID 18185498 DOI: 10.1038/Sj.Npp.1301663  0.722
2008 Caron M, Masri B, Beaulieu J, Salahpour A, Ramsey A, Sotnikova T, Gainetdinov R. S.20.03 β-Arrestin-dependent DAD2R/Akt/GSK3β signaling: relationship to mood stabilisers and antipsychotics European Neuropsychopharmacology. 18: S184. DOI: 10.1016/S0924-977X(08)70190-1  0.66
2006 Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/J.Neuron.2006.08.005  0.641
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