| Year |
Citation |
Score |
| 2023 |
Ayaz P, Lyczek A, Paung Y, Mingione VR, Iacob RE, de Waal PW, Engen JR, Seeliger MA, Shan Y, Shaw DE. Structural mechanism of a drug-binding process involving a large conformational change of the protein target. Nature Communications. 14: 1885. PMID 37019905 DOI: 10.1038/s41467-023-36956-5 |
0.386 |
|
| 2020 |
de Waal PW, Shi J, You E, Wang X, Melcher K, Jiang Y, Xu HE, Dickson BM. Molecular mechanisms of fentanyl mediated β-arrestin biased signaling. Plos Computational Biology. 16: e1007394. PMID 32275713 DOI: 10.1371/Journal.Pcbi.1007394 |
0.331 |
|
| 2020 |
Zhuang Y, Liu H, Edward Zhou X, Kumar Verma R, de Waal PW, Jang W, Xu TH, Wang L, Meng X, Zhao G, Kang Y, Melcher K, Fan H, Lambert NA, Eric Xu H, et al. Structure of formylpeptide receptor 2-G complex reveals insights into ligand recognition and signaling. Nature Communications. 11: 885. PMID 32060286 DOI: 10.1038/S41467-020-14728-9 |
0.4 |
|
| 2020 |
Ma S, Shen Q, Zhao LH, Mao C, Zhou XE, Shen DD, de Waal PW, Bi P, Li C, Jiang Y, Wang MW, Sexton PM, Wootten D, Melcher K, Zhang Y, et al. Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Molecular Cell. PMID 32004470 DOI: 10.1016/J.Molcel.2020.01.013 |
0.405 |
|
| 2019 |
Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, et al. A complex structure of arrestin-2 bound to a G protein-coupled receptor. Cell Research. PMID 31776446 DOI: 10.1038/S41422-019-0256-2 |
0.362 |
|
| 2019 |
Dutka P, Mukherjee S, Gao X, Kang Y, de Waal PW, Wang L, Zhuang Y, Melcher K, Zhang C, Xu HE, Kossiakoff AA. Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM. Structure (London, England : 1993). PMID 31669042 DOI: 10.1016/J.Str.2019.10.004 |
0.335 |
|
| 2019 |
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, et al. Structure and dynamics of the active human parathyroid hormone receptor-1. Science (New York, N.Y.). 364: 148-153. PMID 30975883 DOI: 10.1126/science.aav7942 |
0.406 |
|
| 2018 |
Gu X, Bridges MD, Yan Y, de Waal P, Zhou XE, Suino-Powell KM, Xu HE, Hubbell WL, Melcher K. Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK). The Journal of Biological Chemistry. PMID 30206123 DOI: 10.1074/Jbc.Ra118.004101 |
0.395 |
|
| 2018 |
Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, et al. Crystal structure of the Frizzled 4 receptor in a ligand-free state. Nature. PMID 30135577 DOI: 10.1038/S41586-018-0447-X |
0.462 |
|
| 2018 |
Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, et al. Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature. PMID 29899450 DOI: 10.1038/S41586-018-0215-Y |
0.343 |
|
| 2018 |
Yin W, Zhou XE, Yang D, de Waal PW, Wang M, Dai A, Cai X, Huang CY, Liu P, Wang X, Yin Y, Liu B, Zhou Y, Wang J, Liu H, et al. Crystal structure of the human 5-HTserotonin receptor bound to an inverse agonist. Cell Discovery. 4: 12. PMID 29560272 DOI: 10.1038/S41421-018-0009-2 |
0.385 |
|
| 2017 |
Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, et al. Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. Cell. 170: 457-469.e13. PMID 28753425 DOI: 10.1016/J.Cell.2017.07.002 |
0.374 |
|
| 2017 |
Gu X, Yan Y, Novick SJ, Kovich A, Goswami D, Ke J, Tan MHE, Wang L, Li X, de Waal P, Webb MR, Griffin PR, Xu HE, Melcher K. Deconvoluting AMP-dependent kinase (AMPK) adenine nucleotide binding and sensing. The Journal of Biological Chemistry. PMID 28615457 DOI: 10.1074/Jbc.M117.793018 |
0.394 |
|
| 2017 |
Yin Y, de Waal P, He Y, Zhao LH, Yang D, Cai X, Jiang Y, Melcher K, Wang MW, Xu HE. Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors. The Journal of Biological Chemistry. PMID 28356352 DOI: 10.1074/Jbc.M117.782987 |
0.373 |
|
| 2016 |
Dickson BM, de Waal PW, Ramjan ZH, Xu HE, Rothbart SB. A fast, open source implementation of adaptive biasing potentials uncovers a ligand design strategy for the chromatin regulator BRD4. The Journal of Chemical Physics. 145: 154113. PMID 27782467 DOI: 10.1063/1.4964776 |
0.329 |
|
| 2016 |
Liu P, Jia MZ, Zhou XE, De Waal PW, Dickson BM, Liu B, Hou L, Yin YT, Kang YY, Shi Y, Melcher K, Xu HE, Jiang Y. The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer. Acta Pharmacologica Sinica. PMID 27498775 DOI: 10.1038/Aps.2016.69 |
0.311 |
|
| 2015 |
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, et al. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature. PMID 26200343 DOI: 10.1038/Nature14656 |
0.38 |
|
| 2015 |
Li X, Wang L, Zhou XE, Ke J, de Waal PW, Gu X, Tan MH, Wang D, Wu D, Xu HE, Melcher K. Structural basis of AMPK regulation by adenine nucleotides and glycogen. Cell Research. 25: 50-66. PMID 25412657 DOI: 10.1038/Cr.2014.150 |
0.354 |
|
| 2014 |
de Waal PW, Sunden KF, Furge LL. Molecular dynamics of CYP2D6 polymorphisms in the absence and presence of a mechanism-based inactivator reveals changes in local flexibility and dominant substrate access channels. Plos One. 9: e108607. PMID 25286176 DOI: 10.1371/Journal.Pone.0108607 |
0.394 |
|
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