Weiguo zhang - Publications

Affiliations: 
Immunology Duke University, Durham, NC 

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gao Y, Li W, Wang Z, Zhang C, He Y, Liu X, Tang K, Zhang W, Long Q, Liu Y, Zhang J, Zhang B, Zhang L. SEL1L preserves CD8 T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis. Cellular & Molecular Immunology. PMID 37644166 DOI: 10.1038/s41423-023-01078-x  0.359
2021 O'Brien SA, Zhu M, Zhang W. Spontaneous Differentiation of T Follicular Helper Cells in LATY136F Mutant Mice. Frontiers in Immunology. 12: 656817. PMID 33912184 DOI: 10.3389/fimmu.2021.656817  0.378
2020 Wu F, Chi Y, Jiang Z, Xu Y, Xie L, Huang F, Wan D, Ni J, Yuan F, Wu X, Zhang Y, Wang L, Ye R, Byeon B, Wang W, ... ... Zhang W, et al. Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis. Nature. PMID 32076270 DOI: 10.1038/S41586-020-2032-3  0.348
2019 Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nature Immunology. PMID 31611699 DOI: 10.1038/S41590-019-0502-2  0.457
2019 Jin Y, Zhu M, Guo Y, Foreman D, Feng F, Duan G, Wu W, Zhang W. Fine particulate matter (PM) enhances FcεRI-mediated signaling and mast cell function. Cellular Signalling. PMID 30707930 DOI: 10.1016/J.Cellsig.2019.01.010  0.379
2018 Zhu M, Foreman DP, O'Brien SA, Jin Y, Zhang W. Phospholipase D in TCR-Mediated Signaling and T Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29386256 DOI: 10.4049/Jimmunol.1701291  0.512
2017 Myers DR, Lau T, Markegard E, Lim HW, Kasler H, Zhu M, Barczak A, Huizar JP, Zikherman J, Erle DJ, Zhang W, Verdin E, Roose JP. Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. Cell Reports. 19: 1558-1571. PMID 28538176 DOI: 10.1016/J.Celrep.2017.04.076  0.462
2015 Zhang B, Wu J, Jiao Y, Bock C, Dai M, Chen B, Chao N, Zhang W, Zhuang Y. Differential Requirements of TCR Signaling in Homeostatic Maintenance and Function of Dendritic Epidermal T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 26408667 DOI: 10.4049/Jimmunol.1501220  0.454
2015 Zhu M, Zou J, Li T, O'Brien SA, Zhang Y, Ogden S, Zhang W. Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26392467 DOI: 10.4049/Jimmunol.1500665  0.584
2015 O'Brien SA, Zhu M, Zhang W. The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 195: 695-705. PMID 26034173 DOI: 10.4049/Jimmunol.1403187  0.441
2014 Sullivan SA, Zhu M, Bao S, Lewis CA, Ou-Yang CW, Zhang W. The role of LAT-PLCγ1 interaction in γδ T cell development and homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 192: 2865-74. PMID 24523509 DOI: 10.4049/Jimmunol.1302493  0.486
2014 Suzuki R, Leach S, Liu W, Ralston E, Scheffel J, Zhang W, Lowell CA, Rivera J. Molecular editing of cellular responses by the high-affinity receptor for IgE. Science (New York, N.Y.). 343: 1021-5. PMID 24505132 DOI: 10.1126/Science.1246976  0.349
2013 Orr SJ, Burg AR, Chan T, Quigley L, Jones GW, Ford JW, Hodge D, Razzook C, Sarhan J, Jones YL, Whittaker GC, Boelte KC, Lyakh L, Cardone M, O'Connor GM, ... ... Zhang W, et al. LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells. Plos Pathogens. 9: e1003357. PMID 23675302 DOI: 10.1371/Journal.Ppat.1003357  0.367
2013 May RM, Okumura M, Hsu CJ, Bassiri H, Yang E, Rak G, Mace EM, Philip NH, Zhang W, Baumgart T, Orange JS, Nichols KE, Kambayashi T. Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. Blood. 121: 3135-46. PMID 23407547 DOI: 10.1182/Blood-2012-12-474361  0.457
2013 Ou-Yang CW, Zhu M, Sullivan SA, Fuller DM, Zhang W. The requirement of linker for activation of T cells in the primary and memory responses of CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 2938-47. PMID 23401587 DOI: 10.4049/Jimmunol.1203163  0.412
2012 Fuller DM, Zhu M, Koonpaew S, Nelson MI, Zhang W. The importance of the Erk pathway in the development of linker for activation of T cells-mediated autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 189: 4005-13. PMID 22984075 DOI: 10.4049/Jimmunol.1201380  0.495
2012 Fuller DM, Zhu M, Song X, Ou-Yang CW, Sullivan SA, Stone JC, Zhang W. Regulation of RasGRP1 function in T cell development and activation by its unique tail domain. Plos One. 7: e38796. PMID 22719950 DOI: 10.1371/Journal.Pone.0038796  0.434
2012 Chen Y, Ci X, Gorentla B, Sullivan SA, Stone JC, Zhang W, Pereira P, Lu J, Zhong XP. Differential requirement of RasGRP1 for γδ T cell development and activation. Journal of Immunology (Baltimore, Md. : 1950). 189: 61-71. PMID 22623331 DOI: 10.4049/Jimmunol.1103272  0.48
2012 Ou-Yang Cw, Zhu M, Fuller DM, Sullivan SA, Chuck MI, Ogden S, Li QJ, Zhang W. Role of LAT in the Granule-Mediated Cytotoxicity of CD8 T Cells Molecular and Cellular Biology. 32: 2674-2684. PMID 22566687 DOI: 10.1128/Mcb.00356-12  0.502
2012 Zhu M, Fuller DM, Ou-Yang CW, Sullivan SA, Zhang W. Tyrosine phosphorylation-independent regulation of lipopolysaccharide-mediated response by the transmembrane adaptor protein LAB. Journal of Immunology (Baltimore, Md. : 1950). 188: 2733-41. PMID 22308309 DOI: 10.4049/Jimmunol.1101581  0.445
2012 Zhu M, Fuller DM, Zhang W. The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development. The Journal of Biological Chemistry. 287: 8135-43. PMID 22262848 DOI: 10.1074/Jbc.M111.320580  0.471
2011 Markegard E, Trager E, Yang CW, Zhang W, Weiss A, Roose JP. Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression. Plos One. 6: e25540. PMID 21966541 DOI: 10.1371/Journal.Pone.0025540  0.467
2011 Fuller DM, Zhu M, Ou-Yang CW, Sullivan SA, Zhang W. A tale of two TRAPs: LAT and LAB in the regulation of lymphocyte development, activation, and autoimmunity. Immunologic Research. 49: 97-108. PMID 21136199 DOI: 10.1007/S12026-010-8197-3  0.471
2010 Shen S, Chuck MI, Zhu M, Fuller DM, Yang CW, Zhang W. The importance of LAT in the activation, homeostasis, and regulatory function of T cells. The Journal of Biological Chemistry. 285: 35393-405. PMID 20837489 DOI: 10.1074/Jbc.M110.145052  0.487
2010 Kambayashi T, Okumura M, Baker RG, Hsu CJ, Baumgart T, Zhang W, Koretzky GA. Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation. Molecular and Cellular Biology. 30: 4188-96. PMID 20606011 DOI: 10.1128/Mcb.00305-10  0.479
2010 Zhang W, Konopleva M, Burks JK, Dywer KC, Schober WD, Yang JY, McQueen TJ, Hung MC, Andreeff M. Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim. Cancer Research. 70: 2424-34. PMID 20215498 DOI: 10.1158/0008-5472.Can-09-0878  0.311
2010 Chuck MI, Zhu M, Shen S, Zhang W. The role of the LAT-PLC-gamma1 interaction in T regulatory cell function. Journal of Immunology (Baltimore, Md. : 1950). 184: 2476-86. PMID 20130215 DOI: 10.4049/Jimmunol.0902876  0.484
2010 Yu K, Shi C, Toral-Barza L, Lucas J, Shor B, Kim JE, Zhang WG, Mahoney R, Gaydos C, Tardio L, Kim SK, Conant R, Curran K, Kaplan J, Verheijen J, et al. Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2. Cancer Research. 70: 621-31. PMID 20068177 DOI: 10.1158/0008-5472.Can-09-2340  0.358
2009 Fuller DM, Zhang W. Regulation of lymphocyte development and activation by the LAT family of adapter proteins. Immunological Reviews. 232: 72-83. PMID 19909357 DOI: 10.1111/J.1600-065X.2009.00828.X  0.483
2009 Malhotra S, Kovats S, Zhang W, Coggeshall KM. Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB. The Journal of Biological Chemistry. 284: 36202-12. PMID 19858206 DOI: 10.1074/Jbc.M109.040089  0.461
2009 Nowak P, Cole DC, Brooijmans N, Bursavich MG, Curran KJ, Ellingboe JW, Gibbons JJ, Hollander I, Hu Y, Kaplan J, Malwitz DJ, Toral-Barza L, Verheijen JC, Zask A, Zhang WG, et al. Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase. Journal of Medicinal Chemistry. 52: 7081-9. PMID 19848404 DOI: 10.1021/Jm9012642  0.308
2009 Hundt M, Harada Y, De Giorgio L, Tanimura N, Zhang W, Altman A. Palmitoylation-dependent plasma membrane transport but lipid raft-independent signaling by linker for activation of T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 1685-94. PMID 19592663 DOI: 10.4049/Jimmunol.0803921  0.451
2009 Malhotra S, Kovats S, Zhang W, Coggeshall KM. B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin. The Journal of Biological Chemistry. 284: 24088-97. PMID 19586920 DOI: 10.1074/Jbc.M109.014209  0.443
2009 Yu K, Toral-Barza L, Shi C, Zhang WG, Lucas J, Shor B, Kim J, Verheijen J, Curran K, Malwitz DJ, Cole DC, Ellingboe J, Ayral-Kaloustian S, Mansour TS, Gibbons JJ, et al. Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin. Cancer Research. 69: 6232-40. PMID 19584280 DOI: 10.1158/0008-5472.Can-09-0299  0.392
2009 Shen S, Lau J, Zhu M, Zou J, Fuller D, Li QJ, Zhang W. The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation. Blood. 114: 74-84. PMID 19401562 DOI: 10.1182/Blood-2008-09-177832  0.403
2009 Shen S, Zhu M, Lau J, Chuck M, Zhang W. The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage. Journal of Immunology (Baltimore, Md. : 1950). 182: 5596-604. PMID 19380807 DOI: 10.4049/Jimmunol.0803170  0.406
2009 Salaski EJ, Krishnamurthy G, Ding WD, Yu K, Insaf SS, Eid C, Shim J, Levin JI, Tabei K, Toral-Barza L, Zhang WG, McDonald LA, Honores E, Hanna C, Yamashita A, et al. Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine. Journal of Medicinal Chemistry. 52: 2181-4. PMID 19309081 DOI: 10.1021/Jm900075G  0.347
2008 Shapiro MJ, Nguyen CT, Aghajanian H, Zhang W, Shapiro VS. Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 181: 7055-61. PMID 18981125 DOI: 10.4049/Jimmunol.181.10.7055  0.494
2008 Whittaker GC, Burshtyn DN, Orr SJ, Quigley L, Hodge DL, Pascal V, Zhang W, McVicar DW. Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire. Blood. 112: 2869-77. PMID 18645037 DOI: 10.1182/Blood-2007-11-121590  0.474
2008 Liu Y, Zhang W. Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells. Journal of Leukocyte Biology. 84: 842-51. PMID 18559951 DOI: 10.1189/Jlb.0208087  0.462
2008 Shor B, Zhang WG, Toral-Barza L, Lucas J, Abraham RT, Gibbons JJ, Yu K. A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis. Cancer Research. 68: 2934-43. PMID 18413763 DOI: 10.1158/0008-5472.Can-07-6487  0.375
2008 Yu K, Toral-Barza L, Shi C, Zhang WG, Zask A. Response and determinants of cancer cell susceptibility to PI3K inhibitors: combined targeting of PI3K and Mek1 as an effective anticancer strategy. Cancer Biology & Therapy. 7: 307-15. PMID 18059185 DOI: 10.4161/Cbt.7.2.5334  0.379
2007 Toral-Barza L, Zhang WG, Huang X, McDonald LA, Salaski EJ, Barbieri LR, Ding WD, Krishnamurthy G, Hu YB, Lucas J, Bernan VS, Cai P, Levin JI, Mansour TS, Gibbons JJ, et al. Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines. Molecular Cancer Therapeutics. 6: 3028-38. PMID 17989320 DOI: 10.1158/1535-7163.Mct-07-0211  0.339
2007 Denning TL, Granger SW, Granger S, Mucida D, Graddy R, Leclercq G, Zhang W, Honey K, Rasmussen JP, Cheroutre H, Rudensky AY, Kronenberg M. Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. Journal of Immunology (Baltimore, Md. : 1950). 178: 4230-9. PMID 17371979 DOI: 10.4049/Jimmunol.178.7.4230  0.431
2007 Liu Y, Zhu M, Nishida K, Hirano T, Zhang W. An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response Journal of Experimental Medicine. 204: 93-103. PMID 17190838 DOI: 10.1084/Jem.20061598  0.449
2007 Mutch CM, Sanyal R, Unruh TL, Grigoriou L, Zhu M, Zhang W, Deans JP. Activation-induced endocytosis of the raft-associated transmembrane adaptor protein LAB/NTAL in B lymphocytes: evidence for a role in internalization of the B cell receptor. International Immunology. 19: 19-30. PMID 17090619 DOI: 10.1093/Intimm/Dxl118  0.427
2006 Zhu M, Koonpaew S, Liu Y, Shen S, Denning T, Dzhagalov I, Rhee I, Zhang W. Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB. Immunity. 25: 757-68. PMID 17081783 DOI: 10.1016/J.Immuni.2006.08.025  0.493
2006 Zhu M, Rhee I, Liu Y, Zhang W. Negative regulation of FcεRI-mediated signaling and mast cell function by the adaptor protein LAX Journal of Biological Chemistry. 281: 18408-18413. PMID 16672218 DOI: 10.1074/Jbc.M601535200  0.494
2006 Koonpaew S, Shen S, Flowers L, Zhang W. LAT-mediated signaling in CD4+CD25+ regulatory T cell development. The Journal of Experimental Medicine. 203: 119-29. PMID 16380508 DOI: 10.1084/Jem.20050903  0.448
2006 Zhang W, Shor B, Yu K. Identification and characterization of a constitutively T-loop phosphorylated and active recombinant S6K1: expression, purification, and enzymatic studies in a high capacity non-radioactive TR-FRET Lance assay. Protein Expression and Purification. 46: 414-420. PMID 16213157 DOI: 10.1016/J.Pep.2005.08.012  0.384
2005 Toral-Barza L, Zhang W, Lamison C, LaRocque J, Gibbons J, Yu K. Characterization of the cloned full-length and a truncated human target of rapamycin: activity, specificity, and enzyme inhibition as studied by a high capacity assay. Biochemical and Biophysical Research Communications. 332: 304-310. PMID 15896331 DOI: 10.1016/J.Bbrc.2005.04.117  0.338
2005 Zhu M, Granillo O, Wen R, Yang K, Dai X, Wang D, Zhang W. Negative regulation of lymphocyte activation by the adaptor protein LAX. Journal of Immunology (Baltimore, Md. : 1950). 174: 5612-9. PMID 15843560 DOI: 10.4049/Jimmunol.174.9.5612  0.508
2005 Zhu M, Shen S, Liu Y, Granillo O, Zhang W. Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development. Journal of Immunology (Baltimore, Md. : 1950). 174: 31-5. PMID 15611224 DOI: 10.4049/Jimmunol.174.1.31  0.473
2004 Zhu M, Liu Y, Koonpaew S, Granillo O, Zhang W. Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL. The Journal of Experimental Medicine. 200: 991-1000. PMID 15477350 DOI: 10.1084/Jem.20041223  0.504
2004 Wen R, Chen Y, Schuman J, Fu G, Yang S, Zhang W, Newman DK, Wang D. An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion. The Embo Journal. 23: 4007-17. PMID 15372077 DOI: 10.1038/Sj.Emboj.7600405  0.407
2004 rcaron VH, ejší, Zhang W, Schraven B. Transmembrane adaptor proteins: organizers of immunoreceptor signalling Nature Reviews Immunology. 4: 603-616. PMID 15286727 DOI: 10.1038/Nri1414  0.37
2004 Zipfel PA, Zhang W, Quiroz M, Pendergast AM. Requirement for Abl kinases in T cell receptor signaling. Current Biology : Cb. 14: 1222-31. PMID 15268851 DOI: 10.1016/J.Cub.2004.07.021  0.422
2004 Janssen E, Zhu M, Craven B, Zhang W. Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-gamma1 binding. Journal of Immunology (Baltimore, Md. : 1950). 172: 6810-9. PMID 15153499 DOI: 10.4049/Jimmunol.172.11.6810  0.501
2004 Koonpaew S, Janssen E, Zhu M, Zhang W. The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB. The Journal of Biological Chemistry. 279: 11229-35. PMID 14722116 DOI: 10.1074/Jbc.M311394200  0.495
2004 Janssen E, Zhang W. Adaptor proteins in lymphocyte activation. Current Opinion in Immunology. 15: 269-76. PMID 12787751 DOI: 10.1016/S0952-7915(03)00044-X  0.362
2004 Hořejší V, Zhang W, Schraven B. Erratum: Transmembrane adaptor proteins: organizers of immunoreceptor signalling Nature Reviews Immunology. 4: 743-743. DOI: 10.1038/Nri1455  0.325
2003 Janssen E, Zhu M, Zhang W, Koonpaew S, Zhang W. LAB: a new membrane-associated adaptor molecule in B cell activation. Nature Immunology. 4: 117-23. PMID 12514734 DOI: 10.1038/Ni882  0.502
2003 Zhu M, Janssen E, Zhang W. Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development. Journal of Immunology (Baltimore, Md. : 1950). 170: 325-33. PMID 12496416 DOI: 10.4049/Jimmunol.170.1.325  0.515
2002 Zhu M, Janssen E, Leung K, Zhang W. Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. The Journal of Biological Chemistry. 277: 46151-8. PMID 12359715 DOI: 10.1074/Jbc.M208946200  0.513
2001 Sommers CL, Menon RK, Grinberg A, Zhang W, Samelson LE, Love PE. Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. The Journal of Experimental Medicine. 194: 135-42. PMID 11457888 DOI: 10.1084/Jem.194.2.135  0.52
2001 Bunnell SC, Kapoor V, Trible RP, Zhang W, Samelson LE. Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. Immunity. 14: 315-29. PMID 11290340 DOI: 10.1016/S1074-7613(01)00112-1  0.464
2000 Saitoh S, Arudchandran R, Manetz TS, Zhang W, Sommers CL, Love PE, Rivera J, Samelson LE. LAT is essential for Fc(epsilon)RI-mediated mast cell activation. Immunity. 12: 525-35. PMID 10843385 DOI: 10.1016/S1074-7613(00)80204-6  0.477
2000 Zhang W, Trible RP, Zhu M, Liu SK, McGlade CJ, Samelson LE. Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. The Journal of Biological Chemistry. 275: 23355-61. PMID 10811803 DOI: 10.1074/Jbc.M000404200  0.421
2000 Zhang W, Samelson LE. The role of membrane-associated adaptors in T cell receptor signalling. Seminars in Immunology. 12: 35-41. PMID 10723796 DOI: 10.1006/Smim.2000.0205  0.513
2000 Martelli MP, Lin H, Zhang W, Samelson LE, Bierer BE. Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. Blood. 96: 2181-2190. DOI: 10.1182/Blood.V96.6.2181.H8002181_2181_2190  0.472
1999 Pasquet JM, Gross B, Quek L, Asazuma N, Zhang W, Sommers CL, Schweighoffer E, Tybulewicz V, Judd B, Lee JR, Koretzky G, Love PE, Samelson LE, Watson SP. LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. Molecular and Cellular Biology. 19: 8326-34. PMID 10567557 DOI: 10.1128/Mcb.19.12.8326  0.369
1999 Bosselut R, Zhang W, Ashe JM, Kopacz JL, Samelson LE, Singer A. Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction. The Journal of Experimental Medicine. 190: 1517-26. PMID 10562325 DOI: 10.1084/Jem.190.10.1517  0.378
1999 Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M. Requirement of the Src Homology 2 Domain Protein Shb for T Cell Receptor-dependent Activation of the Interleukin-2 Gene Nuclear Factor for Activation of T Cells Element in Jurkat T Cells Journal of Biological Chemistry. 274: 28050-28057. PMID 10488157 DOI: 10.1074/Jbc.274.39.28050  0.52
1999 Zhang W, Irvin BJ, Trible RP, Abraham RT, Samelson LE. Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. International Immunology. 11: 943-50. PMID 10360968 DOI: 10.1093/Intimm/11.6.943  0.473
1999 Facchetti F, Chan JK, Zhang W, Tironi A, Chilosi M, Parolini S, Notarangelo LD, Samelson LE. Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions. The American Journal of Pathology. 154: 1037-46. PMID 10233842 DOI: 10.1016/S0002-9440(10)65356-4  0.458
1999 Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, DeJarnette JB, Trible RP, Grinberg A, Tsay HC, Jacobs HM, Kessler CM, Long EO, Love PE, Samelson LE. Essential role of LAT in T cell development. Immunity. 10: 323-32. PMID 10204488 DOI: 10.1016/S1074-7613(00)80032-1  0.508
1998 Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, Straus D, Samelson LE, Thompson CB, Bluestone JA. Molecular Basis of T Cell Inactivation by CTLA-4 Science. 282: 2263-2266. PMID 9856951 DOI: 10.1126/Science.282.5397.2263  0.492
1998 Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity. 9: 617-26. PMID 9846483 DOI: 10.1016/S1074-7613(00)80659-7  0.471
1998 Zhang W, Trible RP, Samelson LE. LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity. 9: 239-46. PMID 9729044 DOI: 10.1016/S1074-7613(00)80606-8  0.455
1998 Griffith CE, Zhang W, Wange RL. ZAP-70-dependent and -independent activation of Erk in Jurkat T cells: Differences in signaling induced by H2O2 and CD3 cross-linking Journal of Biological Chemistry. 273: 10771-10776. PMID 9553143 DOI: 10.1074/Jbc.273.17.10771  0.501
1998 Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell. 92: 83-92. PMID 9489702 DOI: 10.1016/S0092-8674(00)80901-0  0.489
1998 Williams BL, Schreiber KL, Zhang W, Wange RL, Samelson LE, Leibson PJ, Abraham RT. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Molecular and Cellular Biology. 18: 1388-99. PMID 9488454 DOI: 10.1128/Mcb.18.3.1388  0.535
1997 Sloan-Lancaster J, Zhang W, Presley J, Williams BL, Abraham RT, Lippincott-Schwartz J, Samelson LE. Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein. The Journal of Experimental Medicine. 186: 1713-24. PMID 9362531 DOI: 10.1084/Jem.186.10.1713  0.468
1991 Nathenson SG, Van Bleek GM, Geliebter J, Hasenkrug K, Imarai M, Joyce S, Kesari K, Kumar A, McCue B, Nakagawa M, Palmieri E, Sheil J, Shibata K, Sun R, Zhang W. Specificity of interaction between MHC (major histocompatibility complex) class I molecules, antigenic peptides, and the T cell receptor Developmental and Comparative Immunology. 15. DOI: 10.1016/0145-305X(91)90201-9  0.342
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