G Greg Wang - Publications

University of North Carolina, Chapel Hill, Chapel Hill, NC 
stem cells, cancer, epigenetics

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lu R, Wang P, Parton T, Zhou Y, Chrysovergis K, Rockowitz S, Chen WY, Abdel-Wahab O, Wade PA, Zheng D, Wang GG. Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development. Cancer Cell. PMID 27344947 DOI: 10.1016/j.ccell.2016.05.008  0.8
2015 Zhang ZM, Rothbart SB, Allison DF, Cai Q, Harrison JS, Li L, Wang Y, Strahl BD, Wang GG, Song J. An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Reports. 12: 1400-6. PMID 26299963 DOI: 10.1016/j.celrep.2015.07.046  0.8
2015 Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, ... ... Wang GG, et al. Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. Blood. 125: 346-57. PMID 25395428 DOI: 10.1182/blood-2014-06-581082  0.8
2014 Gough SM, Lee F, Yang F, Walker RL, Zhu YJ, Pineda M, Onozawa M, Chung YJ, Bilke S, Wagner EK, Denu JM, Ning Y, Xu B, Wang GG, Meltzer PS, et al. NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discovery. 4: 564-77. PMID 24535671 DOI: 10.1158/2159-8290.CD-13-0419  0.8
2013 Konze KD, Ma A, Li F, Barsyte-Lovejoy D, Parton T, Macnevin CJ, Liu F, Gao C, Huang XP, Kuznetsova E, Rougie M, Jiang A, Pattenden SG, Norris JL, James LI, ... ... Wang GG, et al. An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. Acs Chemical Biology. 8: 1324-34. PMID 23614352 DOI: 10.1021/cb400133j  0.8
2013 Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Molecular Cell. 49: 571-82. PMID 23273982 DOI: 10.1016/j.molcel.2012.11.026  0.8
2012 Kumar GS, Chang W, Xie T, Patel A, Zhang Y, Wang GG, David G, Radhakrishnan I. Sequence requirements for combinatorial recognition of histone H3 by the MRG15 and Pf1 subunits of the Rpd3S/Sin3S corepressor complex. Journal of Molecular Biology. 422: 519-31. PMID 22728643 DOI: 10.1016/j.jmb.2012.06.013  0.8
2010 Chi P, Allis CD, Wang GG. Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers. Nature Reviews. Cancer. 10: 457-69. PMID 20574448 DOI: 10.1038/nrc2876  0.8
2010 Milne TA, Kim J, Wang GG, Stadler SC, Basrur V, Whitcomb SJ, Wang Z, Ruthenburg AJ, Elenitoba-Johnson KS, Roeder RG, Allis CD. Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis. Molecular Cell. 38: 853-63. PMID 20541448 DOI: 10.1016/j.molcel.2010.05.011  0.8
2010 Wang Z, Song J, Milne TA, Wang GG, Li H, Allis CD, Patel DJ. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 141: 1183-94. PMID 20541251 DOI: 10.1016/j.cell.2010.05.016  0.8
2009 Wang GG, Allis CD. "Misinterpretation" of a histone mark is linked to aberrant stem cells and cancer development. Cell Cycle (Georgetown, Tex.). 8: 1982-3. PMID 19550157  0.8
2009 Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature. 459: 847-51. PMID 19430464 DOI: 10.1038/nature08036  0.8
2008 Baker LA, Allis CD, Wang GG. PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks. Mutation Research. 647: 3-12. PMID 18682256 DOI: 10.1016/j.mrfmmm.2008.07.004  0.8
2007 Wang GG, Allis CD, Chi P. Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling. Trends in Molecular Medicine. 13: 373-80. PMID 17822959 DOI: 10.1016/j.molmed.2007.07.004  0.8
2007 Wang GG, Allis CD, Chi P. Chromatin remodeling and cancer, Part I: Covalent histone modifications. Trends in Molecular Medicine. 13: 363-72. PMID 17822958 DOI: 10.1016/j.molmed.2007.07.003  0.8
2007 Wang GG, Cai L, Pasillas MP, Kamps MP. NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis. Nature Cell Biology. 9: 804-12. PMID 17589499 DOI: 10.1038/ncb1608  0.8
2007 Wang GG, Kamps MP. Survival signaling in HoxA9/Meis1 AML Blood. 109: 3619-3620. DOI: 10.1182/blood-2007-02-072785  0.8
2006 Wang GG, Pasillas MP, Kamps MP. Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes. Molecular and Cellular Biology. 26: 3902-16. PMID 16648484 DOI: 10.1128/MCB.26.10.3902-3916.2006  0.8
2006 Wang GG, Calvo KR, Pasillas MP, Sykes DB, Häcker H, Kamps MP. Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8. Nature Methods. 3: 287-93. PMID 16554834 DOI: 10.1038/nmeth865  0.8
2006 Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang GG, Kamps MP, Raz E, Wagner H, Häcker G, Mann M, Karin M. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature. 439: 204-7. PMID 16306937 DOI: 10.1038/nature04369  0.8
2005 Wang GG, Pasillas MP, Kamps MP. Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus. Blood. 106: 254-64. PMID 15755900 DOI: 10.1182/blood-2004-12-4664  0.8
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