Chaya Brodie - Publications

Affiliations: 
Life Sciences Bar-Ilan University, Jerusalem, Jerusalem District, Israel 

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nizar R, Cazacu S, Xiang C, Krasner M, Barbiro-Michaely E, Gerber D, Schwartz J, Fried I, Yuval S, Brodie A, Kazimirsky G, Amos N, Unger R, Brown S, Rogers L, ... ... Brodie C, et al. Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles. Cells. 12. PMID 37566001 DOI: 10.3390/cells12151921  0.304
2019 Morgoulis D, Berenstein P, Cazacu S, Kazimirsky G, Dori A, Barnea ER, Brodie C. sPIF promotes myoblast differentiation and utrophin expression while inhibiting fibrosis in Duchenne muscular dystrophy via the H19/miR-675/let-7 and miR-21 pathways. Cell Death & Disease. 10: 82. PMID 30692507 DOI: 10.1038/S41419-019-1307-9  0.769
2018 Bier A, Berenstein P, Kronfeld N, Morgoulis D, Ziv-Av A, Goldstein H, Kazimirsky G, Cazacu S, Meir R, Popovtzer R, Dori A, Brodie C. Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy. Biomaterials. 174: 67-78. PMID 29783118 DOI: 10.1016/J.Biomaterials.2018.04.055  0.764
2017 Shwartz A, Betzer O, Kronfeld N, Kazimirsky G, Cazacu S, Finniss S, Lee HK, Motiei M, Dagan SY, Popovtzer R, Brodie C, Yadid G. Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression. Theranostics. 7: 2690-2703. PMID 28819456 DOI: 10.7150/Thno.18914  0.335
2017 Brodie S, Kyung Lee H, Jiang W, Cazacu S, Xiang C, Poisson LM, Datta I, Kalkanis S, Ginsberg D, Brodie C. The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells. Oncotarget. PMID 28423669 DOI: 10.18632/Oncotarget.15991  0.467
2017 Migliara G, Mueller M, Piermattei A, Brodie C, Paidas MJ, Barnea ER, Ria F. PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model. Oncotarget. 8: 21834-21851. PMID 28423529 DOI: 10.18632/Oncotarget.15662  0.328
2017 Jiang W, Brodie S, Cazacu S, Xiang C, Poisson L, Kalkanis S, Ginsberg D, Brodie C. Abstract 2543: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Cancer Research. 77: 2543-2543. DOI: 10.1158/1538-7445.Am2017-2543  0.371
2016 Kazimirsky G, Jiang W, Slavin S, Ziv-Av A, Brodie C. Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL. Stem Cell Research & Therapy. 7: 149. PMID 27724977 DOI: 10.1186/S13287-016-0414-0  0.795
2016 Meir R, Betzer O, Motiei M, Kronfeld N, Brodie C, Popovtzer R. Design Principles for Noninvasive, Longitudinal and Quantitative Cell Tracking with Nanoparticle-Based CT Imaging. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27720990 DOI: 10.1016/J.Nano.2016.09.013  0.358
2016 Jiang W, Finniss S, Cazacu S, Xiang C, Brodie Z, Mikkelsen T, Poisson L, Shackelford DB, Brodie C. Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma. Oncotarget. PMID 27486821 DOI: 10.18632/Oncotarget.10919  0.459
2016 Shainer R, Almogi-Hazan O, Berger A, Hinden L, Mueller M, Brodie C, Simillion C, Paidas M, Barnea ER, Or R. PreImplantation factor (PIF) therapy provides comprehensive protection against radiation induced pathologies. Oncotarget. PMID 27449294 DOI: 10.18632/Oncotarget.10635  0.355
2016 Parajuli P, Anand R, Mandalaparty C, Suryadevara R, Sriranga PU, Michelhaugh SK, Cazacu S, Finniss S, Thakur A, Lum LG, Schalk D, Brodie C, Mittal S. Preferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal. Oncotarget. PMID 26755664 DOI: 10.18632/Oncotarget.6847  0.319
2015 Shilo M, Berenstein P, Dreifuss T, Nash Y, Goldsmith G, Kazimirsky G, Motiei M, Frenkel D, Brodie C, Popovtzer R. Insulin-coated gold nanoparticles as a new concept for personalized and adjustable glucose regulation. Nanoscale. PMID 26583784 DOI: 10.1039/C5Nr04881H  0.725
2015 Ziv-Av A, Giladi ND, Lee HK, Cazacu S, Finniss S, Xiang C, Pauker MH, Barda-Saad M, Poisson L, Brodie C. RTVP-1 regulates glioma cell migration and invasion via interaction with N-WASP and hnRNPK. Oncotarget. 6: 19826-40. PMID 26305187 DOI: 10.18632/Oncotarget.4471  0.785
2015 Giladi ND, Ziv-Av A, Lee HK, Finniss S, Cazacu S, Xiang C, Ben-Asher HW, deCarvalho A, Mikkelsen T, Poisson L, Brodie C. RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop. Oncotarget. PMID 26267319 DOI: 10.18632/Oncotarget.4205  0.804
2015 Lee HK, Finniss S, Cazacu S, Xiang C, Poisson LM, Blumberg PM, Brodie C. RasGRP3 regulates the migration of glioma cells via interaction with Arp3. Oncotarget. 6: 1850-64. PMID 25682201 DOI: 10.18632/Oncotarget.2575  0.564
2015 Parajuli P, Anand R, Mandalaparty C, Suryadevara R, Sriranga P, Michelhaugh S, Thakur A, Lum LG, Brodie C, Mittal S. Functional IL-17R in glioma stem cells: potential role in tumor progression and therapeutic implications Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P412  0.327
2015 Brodie C, Buchris E, Finniss S, Cazacu S, Xiang C, Lee HK, Poisson L. Abstract 2327: Placenta-derived mesenchymal stem cells and their secreted exosomes inhibit the self-renewal and stemness of glioma stem cells in vitro and in vivo Cancer Research. 75: 2327-2327. DOI: 10.1158/1538-7445.Am2015-2327  0.429
2014 Betzer O, Shwartz A, Motiei M, Kazimirsky G, Gispan I, Damti E, Brodie C, Yadid G, Popovtzer R. Nanoparticle-based CT imaging technique for longitudinal and quantitative stem cell tracking within the brain: application in neuropsychiatric disorders. Acs Nano. 8: 9274-85. PMID 25133802 DOI: 10.1021/Nn503131H  0.352
2014 Lee HK, Finniss S, Cazacu S, Xiang C, Brodie C. Mesenchymal stem cells deliver exogenous miRNAs to neural cells and induce their differentiation and glutamate transporter expression. Stem Cells and Development. 23: 2851-61. PMID 25036385 DOI: 10.1089/Scd.2014.0146  0.35
2014 Lee HK, Buchris E, Finniss S, Cazacu S, Xiang C, Poisson L, Brodie C. Et-33Placenta-Derived Mesenchymal Stem Cells And Their Secreted Exosomes Inhibit The Self-Renewal And Stemness Of Glioma Stem Cells In Vitro And In Vivo Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou255.33  0.421
2014 Giladi N, Lee HK, Finniss S, Cazacu S, Xiang C, Poisson L, Mikkelsen T, Ziv-Av A, Brodie C. CS-09 * RTVP-1 PROMOTES THE MESENCHYMAL TRANSFORMATION OF GLIOMA STEM CELLS VIA THE CXCR4 AND IL-6 PATHWAYS Neuro-Oncology. 16: v52-v53. DOI: 10.1093/Neuonc/Nou242.9  0.806
2014 Bier A, Finniss S, Cazacu S, Xiang C, Lee HK, Rand D, Yalon M, Toren A, Poisson L, Brodie C. CB-02MiRNA EXPRESSION PROFILES OF GLIOMA STEM CELLS AND THEIR ASSOCIATION WITH THE MESENCHYMAL TRANSFORMATION OF THESE CELLS. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou241.2  0.374
2014 Benisvy-Aharonovich E, Shimanovich U, Kronfeld N, Giladi N, Bier A, Kazimirsky G, Gedanken A, Brodie C. Pre-miRNA expressing plasmid delivery for anti-cancer therapy Med. Chem. Commun.. 5: 459-462. DOI: 10.1039/C3Md00314K  0.309
2013 Bier A, Giladi N, Kronfeld N, Lee HK, Cazacu S, Finniss S, Xiang C, Poisson L, deCarvalho AC, Slavin S, Jacoby E, Yalon M, Toren A, Mikkelsen T, Brodie C. MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1. Oncotarget. 4: 665-76. PMID 23714687 DOI: 10.18632/Oncotarget.928  0.381
2013 Lee HK, Finniss S, Cazacu S, Bucris E, Ziv-Av A, Xiang C, Bobbitt K, Rempel SA, Hasselbach L, Mikkelsen T, Slavin S, Brodie C. Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal. Oncotarget. 4: 346-61. PMID 23548312 DOI: 10.18632/Oncotarget.868  0.785
2013 Lee HK, Bier A, Cazacu S, Finniss S, Xiang C, Twito H, Poisson LM, Mikkelsen T, Slavin S, Jacoby E, Yalon M, Toren A, Rempel SA, Brodie C. MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor. Plos One. 8: e54652. PMID 23390502 DOI: 10.1371/Journal.Pone.0054652  0.428
2013 Perlstein B, Finniss SA, Miller C, Okhrimenko H, Kazimirsky G, Cazacu S, Lee HK, Lemke N, Brodie S, Umansky F, Rempel SA, Rosenblum M, Mikklesen T, Margel S, Brodie C. TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo. Neuro-Oncology. 15: 29-40. PMID 23144078 DOI: 10.1093/Neuonc/Nos248  0.348
2013 Slavin S, Kazimirsky G, Ziv-Av A, Brodie C. Role of mesenchymal stem cells in delivering Newcastle disease virus to glioma cells and glioma stem cells and enhancing the oncolytic effect of the virus by secreting TRAIL. Journal of Clinical Oncology. 31: 3100-3100. DOI: 10.1200/Jco.2013.31.15_Suppl.3100  0.801
2013 Brodie C, Giladi N, Ziv-Av A, Lee HK, Finniss S, Cazacu S, Xiang C, Poisson L, Slavin S, Mikkelsen T. Effect of RTVP-1 on the mesenchymal transformation of glioma stem cells (GSCs) and their self-renewal and migration. Journal of Clinical Oncology. 31: 2073-2073. DOI: 10.1200/Jco.2013.31.15_Suppl.2073  0.794
2012 Schultz CR, Golembieski WA, King DA, Brown SL, Brodie C, Rempel SA. Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival. Molecular Cancer. 11: 20. PMID 22480225 DOI: 10.1186/1476-4598-11-20  0.368
2012 Brutman-Barazani T, Horovitz-Fried M, Aga-Mizrachi S, Brand C, Brodie C, Rosa J, Sampson SR. Protein kinase Cδ but not PKCα is involved in insulin-induced glucose metabolism in hepatocytes. Journal of Cellular Biochemistry. 113: 2064-76. PMID 22271577 DOI: 10.1002/Jcb.24078  0.311
2012 Kozono D, Nitta M, Sampetrean O, Kimberly N, Kushwaha D, Merzon D, Ligon K, Zhu S, Zhu K, Kim TH, Kwon C, Becher O, Saya H, Chen CC, Donovan LK, ... ... Brodie C, et al. LAB-STEM CELLS Neuro-Oncology. 14: vi142-vi152. DOI: 10.1093/Neuonc/Nos239  0.776
2012 Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Brodie C, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220  0.316
2011 Lomonaco SL, Finniss S, Xiang C, Lee HK, Jiang W, Lemke N, Rempel SA, Mikkelsen T, Brodie C. Cilengitide induces autophagy-mediated cell death in glioma cells. Neuro-Oncology. 13: 857-65. PMID 21788343 DOI: 10.1093/Neuonc/Nor073  0.442
2011 Ziv-Av A, Taller D, Attia M, Xiang C, Lee HK, Cazacu S, Finniss S, Kazimirsky G, Sarid R, Brodie C. RTVP-1 expression is regulated by SRF downstream of protein kinase C and contributes to the effect of SRF on glioma cell migration. Cellular Signalling. 23: 1936-43. PMID 21777672 DOI: 10.1016/J.Cellsig.2011.07.001  0.804
2011 Kahana S, Finniss S, Cazacu S, Xiang C, Lee HK, Brodie S, Goldstein RS, Roitman V, Slavin S, Mikkelsen T, Brodie C. Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions. Cellular Signalling. 23: 1348-57. PMID 21440622 DOI: 10.1016/J.Cellsig.2011.03.017  0.431
2010 Dobkin-Bekman M, Rahamin-Ben Navi L, Ben-Navi LR, Shterntal B, Sviridonov L, Przedecki F, Naidich-Exler M, Brodie C, Seger R, Naor Z. Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase. Endocrinology. 151: 4894-907. PMID 20810567 DOI: 10.1210/En.2010-0114  0.336
2010 Brand C, Horovitz-Fried M, Inbar A, Tamar-Brutman-Barazani, Brodie C, Sampson SR. Insulin stimulation of PKCδ triggers its rapid degradation via the ubiquitin-proteasome pathway. Biochimica Et Biophysica Acta. 1803: 1265-75. PMID 20708645 DOI: 10.1016/J.Bbamcr.2010.07.006  0.307
2010 Sampson SR, Bucris E, Horovitz-Fried M, Parnas A, Kahana S, Abitbol G, Chetboun M, Rosenzweig T, Brodie C, Frankel S. Insulin increases H2O2-induced pancreatic beta cell death. Apoptosis : An International Journal On Programmed Cell Death. 15: 1165-76. PMID 20544287 DOI: 10.1007/S10495-010-0517-5  0.341
2010 Jacob AI, Horovitz-Fried M, Aga-Mizrachi S, Brutman-Barazani T, Okhrimenko H, Zick Y, Brodie C, Sampson SR. The regulatory domain of protein kinase C delta positively regulates insulin receptor signaling. Journal of Molecular Endocrinology. 44: 155-69. PMID 19952103 DOI: 10.1677/Jme-09-0119  0.358
2010 Lee JK, Av AZ, Xiang C, Cazacu S, Finniss S, Giladi N, Barda-Saad M, Brodie C. Abstract LB-268: RTVP-1 regulates glioma cell migration and podosome formation via interaction with N-WASP Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-268  0.348
2009 Lomonaco SL, Finniss S, Xiang C, DeCarvalho A, Umansky F, Kalkanis SN, Mikkelsen T, Brodie C. The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells International Journal of Cancer. 125: 717-722. PMID 19431142 DOI: 10.1002/Ijc.24402  0.361
2009 Gusarova GA, Dada LA, Kelly AM, Brodie C, Witters LA, Chandel NS, Sznajder JI. Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta. Molecular and Cellular Biology. 29: 3455-64. PMID 19380482 DOI: 10.1128/Mcb.00054-09  0.308
2009 Mikkelsen T, Brodie C, Finniss S, Berens ME, Rennert JL, Nelson K, Lemke N, Brown SL, Hahn D, Neuteboom B, Goodman SL. Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency. International Journal of Cancer. Journal International Du Cancer. 124: 2719-27. PMID 19199360 DOI: 10.1002/Ijc.24240  0.33
2009 Ostrovsky S, Kazimirsky G, Gedanken A, Brodie C. Selective cytotoxic effect of ZnO nanoparticles on glioma cells Nano Research. 2: 882-890. DOI: 10.1007/S12274-009-9089-5  0.328
2008 Jiang W, Xiang C, Cazacu S, Brodie C, Mikkelsen T. Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration. Neoplasia (New York, N.Y.). 10: 1335-42. PMID 19048112 DOI: 10.1593/Neo.08694  0.438
2008 Golembieski WA, Thomas SL, Schultz CR, Yunker CK, McClung HM, Lemke N, Cazacu S, Barker T, Sage EH, Brodie C, Rempel SA. HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion. Glia. 56: 1061-75. PMID 18442089 DOI: 10.1002/Glia.20679  0.454
2008 Lomonaco SL, Kahana S, Blass M, Brody Y, Okhrimenko H, Xiang C, Finniss S, Blumberg PM, Lee HK, Brodie C. Phosphorylation of protein kinase Cδ on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: Role in the apoptotic effect of etoposide Journal of Biological Chemistry. 283: 17731-17739. PMID 18434324 DOI: 10.1074/Jbc.M801727200  0.505
2008 Lee HK, Xiang C, Cazacu S, Finniss S, Kazimirsky G, Lemke N, Lehman NL, Rempel SA, Mikkelsen T, Brodie C. GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis. Neuro-Oncology. 10: 236-43. PMID 18403493 DOI: 10.1215/15228517-2008-006  0.329
2008 Yunker CK, Golembieski W, Lemke N, Schultz CR, Cazacu S, Brodie C, Rempel SA. SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion. International Journal of Cancer. Journal International Du Cancer. 122: 2735-43. PMID 18350569 DOI: 10.1002/Ijc.23450  0.348
2008 Jiang W, Cazacu S, Xiang C, Zenklusen JC, Fine HA, Berens M, Armstrong B, Brodie C, Mikkelsen T. FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway. Neoplasia (New York, N.Y.). 10: 235-43. PMID 18320068 DOI: 10.1593/Neo.07929  0.422
2008 Zhu L, Brodie C, Balasubramanian S, Eckert RL. Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311. The Journal of Investigative Dermatology. 128: 833-45. PMID 17943181 DOI: 10.1038/Sj.Jid.5701103  0.308
2007 Xiang C, Sarid R, Cazacu S, Finniss S, Lee HK, Ziv-Av A, Mikkelsen T, Brodie C. Cloning and characterization of human RTVP-1b, a novel splice variant of RTVP-1 in glioma cells. Biochemical and Biophysical Research Communications. 362: 612-8. PMID 17825796 DOI: 10.1016/J.Bbrc.2007.08.138  0.767
2007 Lu W, Lee HK, Xiang C, Finniss S, Brodie C. The phosphorylation of tyrosine 332 is necessary for the caspase 3-dependent cleavage of PKCdelta and the regulation of cell apoptosis. Cellular Signalling. 19: 2165-73. PMID 17658731 DOI: 10.1016/J.Cellsig.2007.06.015  0.376
2007 Gomel R, Xiang C, Finniss S, Lee HK, Lu W, Okhrimenko H, Brodie C. The localization of protein kinase Cdelta in different subcellular sites affects its proapoptotic and antiapoptotic functions and the activation of distinct downstream signaling pathways. Molecular Cancer Research : McR. 5: 627-39. PMID 17579121 DOI: 10.1158/1541-7786.Mcr-06-0255  0.365
2007 Lu W, Finnis S, Xiang C, Lee HK, Markowitz Y, Okhrimenko H, Brodie C. Tyrosine 311 is phosphorylated by c-Abl and promotes the apoptotic effect of PKCdelta in glioma cells. Biochemical and Biophysical Research Communications. 352: 431-6. PMID 17126298 DOI: 10.1016/J.Bbrc.2006.11.028  0.349
2007 Steinhart R, Kazimirsky G, Okhrimenko H, Ben-Hur T, Brodie C. PKCepsilon induces astrocytic differentiation of multipotential neural precursor cells. Glia. 55: 224-32. PMID 17091491 DOI: 10.1002/Glia.20454  0.408
2006 Rosenzweig T, Ziv-Av A, Xiang C, Lu W, Cazacu S, Taler D, Miller CG, Reich R, Shoshan Y, Anikster Y, Kazimirsky G, Sarid R, Brodie C. Related to testes-specific, vespid, and pathogenesis protein-1 (RTVP-1) is overexpressed in gliomas and regulates the growth, survival, and invasion of glioma cells. Cancer Research. 66: 4139-48. PMID 16618735 DOI: 10.1158/0008-5472.Can-05-2851  0.814
2006 Cohen A, Brodie C, Sarid R. An essential role of ERK signalling in TPA-induced reactivation of Kaposi's sarcoma-associated herpesvirus. The Journal of General Virology. 87: 795-802. PMID 16528027 DOI: 10.1099/Vir.0.81619-0  0.346
2006 Voss TT, Bobbitt KR, Brodie C, Synder E, Miller CG. 1072. Delivery of Oncolytic Herpes Simplex Virus to Infiltrative Brain Tumor Sites Via Neuronal Stem Cells Molecular Therapy. 13: S411. DOI: 10.1016/J.Ymthe.2006.08.1171  0.354
2006 Steinhart R, Kazimirsky G, Okhrimenko H, Ben‐Hur T, Brodie C. [P159]: PKCɛ induces astrogenesis in multipotential neural precursor cells International Journal of Developmental Neuroscience. 24: 563-564. DOI: 10.1016/J.Ijdevneu.2006.09.219  0.336
2006 Okhrimenko H, Lu W, Xiang C, Gomel R, Blass M, Brodie C. [P83A]: PKCδ as a moelcular switch in the apoptosis and survival of glioma cells International Journal of Developmental Neuroscience. 24: 531-531. DOI: 10.1016/J.Ijdevneu.2006.09.145  0.309
2005 Okhrimenko H, Lu W, Xiang C, Hamburger N, Kazimirsky G, Brodie C. Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells. Cancer Research. 65: 7301-9. PMID 16103081 DOI: 10.1158/0008-5472.Can-05-1064  0.428
2005 Okhrimenko H, Lu W, Xiang C, Ju D, Blumberg PM, Gomel R, Kazimirsky G, Brodie C. Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis. The Journal of Biological Chemistry. 280: 23643-52. PMID 15774464 DOI: 10.1074/Jbc.M501374200  0.544
2005 Petit I, Goichberg P, Spiegel A, Peled A, Brodie C, Seger R, Nagler A, Alon R, Lapidot T. Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. The Journal of Clinical Investigation. 115: 168-76. PMID 15630457 DOI: 10.1172/JCI21773  0.312
2005 Petit I, Goichberg P, Spiegel A, Peled A, Brodie C, Seger R, Nagler A, Alon R, Lapidot T. Atypical PKC-ζ regulates SDF-1–mediated migration and development of human CD34+ progenitor cells Journal of Clinical Investigation. 115: 168-176. DOI: 10.1172/Jci200521773  0.421
2004 Deutsch E, Cohen A, Kazimirsky G, Dovrat S, Rubinfeld H, Brodie C, Sarid R. Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 78: 10187-92. PMID 15331751 DOI: 10.1128/Jvi.78.18.10187-10192.2004  0.344
2004 Brodie C, Steinhart R, Kazimirsky G, Rubinfeld H, Hyman T, Ayres JN, Hur GM, Toth A, Yang D, Garfield SH, Stone JC, Blumberg PM. PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters. Molecular Pharmacology. 66: 76-84. PMID 15213298 DOI: 10.1124/Mol.66.1.76  0.534
2003 Kim SG, Gao ZG, Soltysiak KA, Chang TS, Brodie C, Jacobson KA. P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis. Cellular and Molecular Neurobiology. 23: 401-18. PMID 12825835 DOI: 10.1023/A:1023696806609  0.375
2003 Brodie C, Blumberg PM. Regulation of cell apoptosis by protein kinase c delta. Apoptosis : An International Journal On Programmed Cell Death. 8: 19-27. PMID 12510148 DOI: 10.1023/A:1021640817208  0.539
2002 Zrachia A, Dobroslav M, Blass M, Kazimirsky G, Kronfeld I, Blumberg PM, Kobiler D, Lustig S, Brodie C. Infection of glioma cells with Sindbis virus induces selective activation and tyrosine phosphorylation of protein kinase C delta. Implications for Sindbis virus-induced apoptosis. The Journal of Biological Chemistry. 277: 23693-701. PMID 11927579 DOI: 10.1074/jbc.M111658200  0.477
2002 Kronfeld I, Kazimirsky G, Gelfand EW, Brodie C. NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta. European Journal of Immunology. 32: 136-43. PMID 11754354 DOI: 10.1002/1521-4141(200201)32:1<136::Aid-Immu136>3.0.Co;2-T  0.365
2002 Blass M, Kronfeld I, Kazimirsky G, Blumberg PM, Brodie C. Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide. Molecular and Cellular Biology. 22: 182-95. PMID 11739733 DOI: 10.1128/Mcb.22.1.182-195.2002  0.565
2001 Appel E, Kazimirsky G, Ashkenazi E, Kim SG, Jacobson KA, Brodie C. Roles of BCL-2 and caspase 3 in the adenosine A3 receptor-induced apoptosis. Journal of Molecular Neuroscience : Mn. 17: 285-92. PMID 11859924 DOI: 10.1385/Jmn:17:3:285  0.302
2001 Sarid R, Ben-Moshe T, Kazimirsky G, Weisberg S, Appel E, Kobiler D, Lustig S, Brodie C. vFLIP protects PC-12 cells from apoptosis induced by Sindbis virus: implications for the role of TNF-alpha. Cell Death and Differentiation. 8: 1224-31. PMID 11753570 DOI: 10.1038/Sj.Cdd.4400926  0.321
2001 Weisberg S, Ashkenazi E, Israel Z, Attia M, Shoshan Y, Umansky F, Brodie C. Anaplastic and atypical meningiomas express high levels of Fas and undergo apoptosis in response to Fas ligation. The American Journal of Pathology. 159: 1193-7. PMID 11583945 DOI: 10.1016/S0002-9440(10)62504-7  0.38
2001 Barouch R, Kazimirsky G, Appel E, Brodie C. Nerve growth factor regulates TNF‐α production in mouse macrophages via MAP kinase activation Journal of Leukocyte Biology. 69: 1019-1026. DOI: 10.1189/Jlb.69.6.1019  0.318
2000 Appel E, Katzoff A, Ben-Moshe T, Kazimirsky G, Kobiler D, Lustig S, Brodie C. Differential regulation of Bcl-2 and Bax expression in cells infected with virulent and nonvirulent strains of sindbis virus. Virology. 276: 238-42. PMID 11040115 DOI: 10.1006/Viro.2000.0458  0.365
2000 Kronfeld I, Kazimirsky G, Lorenzo PS, Garfield SH, Blumberg PM, Brodie C. Phosphorylation of protein kinase Cdelta on distinct tyrosine residues regulates specific cellular functions. The Journal of Biological Chemistry. 275: 35491-8. PMID 10945993 DOI: 10.1074/Jbc.M005991200  0.548
2000 Barouch R, Appel E, Kazimirsky G, Braun A, Renz H, Brodie C. Differential regulation of neurotrophin expression by mitogens and neurotransmitters in mouse lymphocytes. Journal of Neuroimmunology. 103: 112-21. PMID 10696906 DOI: 10.1016/S0165-5728(99)00233-7  0.38
1999 Melamed I, Patel H, Brodie C, Gelfand EW. Activation of Vav and Ras through the nerve growth factor and B cell receptors by different kinases. Cellular Immunology. 191: 83-9. PMID 9973529 DOI: 10.1006/Cimm.1998.1402  0.322
1999 Bíró T, Brodie C, Modarres S, Lewin NE, Acs P, Blumberg PM. Specific vanilloid responses in C6 rat glioma cells. Brain Research. Molecular Brain Research. 56: 89-98. PMID 9602075 DOI: 10.1016/S0169-328X(98)00033-3  0.539
1998 Brodie C, Bogi K, Acs P, Lorenzo PS, Baskin L, Blumberg PM. Protein kinase C delta (PKCdelta) inhibits the expression of glutamine synthetase in glial cells via the PKCdelta regulatory domain and its tyrosine phosphorylation. The Journal of Biological Chemistry. 273: 30713-8. PMID 9804846 DOI: 10.1074/Jbc.273.46.30713  0.55
1998 Brodie C, Blumberg PM, Jacobson KA. Activation of the A2A adenosine receptor inhibits nitric oxide production in glial cells. Febs Letters. 429: 139-42. PMID 9650577 DOI: 10.1016/S0014-5793(98)00556-0  0.476
1998 Brodie C, Kuperstein I, Acs P, Blumberg PM. Differential role of specific PKC isoforms in the proliferation of glial cells and the expression of the astrocytic markers GFAP and glutamine synthetase. Brain Research. Molecular Brain Research. 56: 108-17. PMID 9602083 DOI: 10.1016/S0169-328X(98)00035-7  0.61
1998 Shalit F, Sredni B, Rosenblatt-Bin H, Kazimirsky G, Brodie C, Huberman M. Beta-amyloid peptide induces tumor necrosis factor-alpha and nitric oxide production in murine macrophage cultures. Neuroreport. 8: 3577-80. PMID 9427329 DOI: 10.1097/00001756-199711100-00031  0.553
1998 Bı́ró T, Maurer M, Modarres S, Lewin NE, Brodie C, Ács G, Ács P, Paus R, Blumberg PM. Characterization of Functional Vanilloid Receptors Expressed by Mast Cells Blood. 91: 1332-1340. DOI: 10.1182/Blood.V91.4.1332  0.502
1997 Appel E, Kolman O, Kazimirsky G, Blumberg PM, Brodie C. Regulation of GDNF expression in cultured astrocytes by inflammatory stimuli. Neuroreport. 8: 3309-12. PMID 9351662 DOI: 10.1097/00001756-199710200-00023  0.528
1997 Ashkenazi E, Deutsch M, Tirosh R, Weinreb A, Tsukerman A, Brodie C. A selective impairment of the IL-2 system in lymphocytes of patients with glioblastomas: increased level of soluble IL-2R and reduced protein tyrosine phosphorylation. Neuroimmunomodulation. 4: 49-56. PMID 9326745 DOI: 10.1159/000097315  0.315
1997 Brodie C, Weizman N, Katzoff A, Lustig S, Kobiler D. Astrocyte activation by Sindbis virus: expression of GFAP, cytokines, and adhesion molecules. Glia. 19: 275-85. PMID 9097072 DOI: 10.1002/(Sici)1098-1136(199704)19:4<275::Aid-Glia1>3.0.Co;2-X  0.364
1997 Zurgil N, Deutsch M, Tirosh R, Brodie C. Indication that intracellular fluorescence polarization of T lymphocytes is cell cycle dependent. Cell Structure and Function. 21: 271-6. PMID 8906363 DOI: 10.1247/Csf.21.271  0.357
1997 Brodie C, Bogi K, Acs P, Lorenzo P, Baskin L, Blumberg P. The regulatory domain of PKCδ mediates its inhibitory effect on glutamine synthetase expresion in C6 glial cells: Role of tyrosine phosphorylation Neuroscience Letters. 237: S12. DOI: 10.1016/S0304-3940(97)90046-X  0.533
1997 Appel E, Kolman O, Kazimirsky G, Tzukerman A, Brodie C. Differential regulation of neurotrophin expression in cultured astrocytes by inflammatory stimuli Neuroscience Letters. 237: S3-S4. DOI: 10.1016/S0304-3940(97)90013-6  0.311
1996 Melamed I, Kelleher CA, Franklin RA, Brodie C, Hempstead B, Kaplan D, Gelfand EW. Nerve growth factor signal transduction in human B lymphocytes is mediated by gp140trk. European Journal of Immunology. 26: 1985-92. PMID 8814235 DOI: 10.1002/Eji.1830260903  0.323
1995 Brodie C. Functional PAF receptors in glia cells: binding parameters and regulation of expression. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 12: 631-40. PMID 7900545 DOI: 10.1016/0736-5748(94)90015-9  0.383
1995 Brodie C. Platelet activating factor induces nerve growth factor production by rat astrocytes. Neuroscience Letters. 186: 5-8. PMID 7783948 DOI: 10.1016/0304-3940(95)11267-Z  0.33
1995 Shalit F, Sredni B, Brodie C, Kott E, Huberman M. T lymphocyte subpopulations and activation markers correlate with severity of Alzheimer's disease. Clinical Immunology and Immunopathology. 75: 246-50. PMID 7768042 DOI: 10.1006/Clin.1995.1078  0.538
1995 Brodie C, Tordai A, Saloga J, Domenico J, Gelfand EW. Ouabain induces inhibition of the progression phase in human T-cell proliferation. Journal of Cellular Physiology. 165: 246-53. PMID 7593202 DOI: 10.1002/Jcp.1041650205  0.323
1995 Kronfeld I, Zsukerman A, Kazimirsky G, Brodie C. Staurosporine induces astrocytic phenotypes and differential expression of specific PKC isoforms in C6 glial cells. Journal of Neurochemistry. 65: 1505-14. PMID 7561844 DOI: 10.1046/J.1471-4159.1995.65041505.X  0.439
1994 Huberman M, Shalit F, Roth-Deri I, Gutman B, Brodie C, Kott E, Sredni B. Correlation of cytokine secretion by mononuclear cells of Alzheimer patients and their disease stage. Journal of Neuroimmunology. 52: 147-152. PMID 8034754 DOI: 10.1016/0165-5728(94)90108-2  0.553
1994 Brodie C, Goldreich N. Interleukin-4 modulates the proliferation and differentiation of glial cells. Journal of Neuroimmunology. 55: 91-7. PMID 7962485 DOI: 10.1016/0165-5728(94)90150-3  0.424
1994 Brodie C, Gelfand EW. Regulation of immunoglobulin production by nerve growth factor: comparison with anti-CD40. Journal of Neuroimmunology. 52: 87-96. PMID 7515902 DOI: 10.1016/0165-5728(94)90166-X  0.341
1992 Brodie C, Vernadakis A. Ethanol increases cholinergic and decreases GABAergic neuronal expression in cultures derived from 8-day-old chick embryo cerebral hemispheres: interaction of ethanol and growth factors. Brain Research. Developmental Brain Research. 65: 253-7. PMID 1572068 DOI: 10.1016/0165-3806(92)90186-Z  0.487
1992 Vernadakis A, Lee K, Kentroti S, Brodie C. Role of astrocytes in aging: late passage primary mouse brain astrocytes and C-6 glial cells as models. Progress in Brain Research. 94: 391-409. PMID 1287725 DOI: 10.1016/S0079-6123(08)61767-7  0.572
1991 Brodie C, Vernadakis A. Muscle-derived factors enhance cholinergic neuronal expression in the chick embryo--II. In culture studies. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 415-26. PMID 1950655 DOI: 10.1016/0736-5748(91)90063-R  0.515
1991 Brodie C, Vernadakis A. Muscle-derived factors enhance cholinergic neuronal expression in the chick embryo--I. In ovo studies. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 405-13. PMID 1950654 DOI: 10.1016/0736-5748(91)90062-Q  0.516
1991 Brodie C, Kentroti S, Vernadakis A. Growth factors attenuate the cholinotoxic effects of ethanol during early neuroembryogenesis in the chick embryo. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 203-13. PMID 1927580 DOI: 10.1016/0736-5748(91)90041-J  0.485
1991 Brodie C, Vernadakis A. Muscle-derived factors reverse the cholinotoxic effects of ethanol during early neuroembryogenesis in the chick embryo. Brain Research. Developmental Brain Research. 61: 183-8. PMID 1752039 DOI: 10.1016/0165-3806(91)90130-B  0.487
1991 Vernadakis A, Kentroti S, Brodie C, Mangoura D, Sakellaridis N. C-6 glioma cells of early passage have progenitor properties in culture. Advances in Experimental Medicine and Biology. 296: 181-95. PMID 1685850 DOI: 10.1007/978-1-4684-8047-4_18  0.578
1991 Brodie C, Vernadakis A. Muscle-derived factors induce proliferation and astrocytic phenotypic expression in C-6 glial cells. Glia. 4: 269-75. PMID 1680101 DOI: 10.1002/Glia.440040304  0.594
1991 Brodie C, Sampson SR. Serum factor induces selective increase in Na-channel expression in cultured skeletal muscle Journal of Cellular Physiology. 148: 48-53. PMID 1650374 DOI: 10.1002/Jcp.1041480106  0.301
1990 Brodie C, Vernadakis A. Critical periods to ethanol exposure during early neuroembryogenesis in the chick embryo: cholinergic neurons. Brain Research. Developmental Brain Research. 56: 223-8. PMID 2261683 DOI: 10.1016/0165-3806(90)90086-E  0.477
1990 Brodie C, Sampson SR. Nerve growth factor and fibroblast growth factor influence post-fusion expression of Na-channels in cultured rat skeletal muscle Journal of Cellular Physiology. 144: 492-497. PMID 2167902 DOI: 10.1002/Jcp.1041440317  0.327
1987 Brodie C, Sampson SR. Nerve growth factor supports growth of rat skeletal myotubes in culture Brain Research. 435: 393-397. PMID 3427468 DOI: 10.1016/0006-8993(87)91632-5  0.301
1985 Brodie C, Bak A, Sampson SR. Dependence of Na+,K+-ATPase and electrogenic component of Em in cultured myotubes on cell fusion. Brain Research. 336: 384-6. PMID 2988705 DOI: 10.1016/0006-8993(85)90674-2  0.311
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