Ivan Dikic - Publications

Affiliations: 
Institute of Biochemistry 2 Goethe University, Frankfurt am Main 

250 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bhattacharya A, Mukherjee R, Kuncha SK, Brunstein ME, Rathore R, Junek S, Münch C, Dikic I. A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins. Nature Cell Biology. 25: 685-698. PMID 37024685 DOI: 10.1038/s41556-023-01125-9  0.765
2022 Hertel A, Alves LM, Dutz H, Tascher G, Bonn F, Kaulich M, Dikic I, Eimer S, Steinberg F, Bremm A. USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction. Cell Reports. 41: 111653. PMID 36476874 DOI: 10.1016/j.celrep.2022.111653  0.346
2022 Mukherjee R, Dikic I. Regulation of Host-Pathogen Interactions via the Ubiquitin System. Annual Review of Microbiology. 76: 211-233. PMID 36075095 DOI: 10.1146/annurev-micro-041020-025803  0.75
2021 Liu Y, Mukherjee R, Bonn F, Colby T, Matic I, Glogger M, Heilemann M, Dikic I. Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection. Cell Death and Differentiation. PMID 34285384 DOI: 10.1038/s41418-021-00830-y  0.781
2021 Armstrong LA, Lange SM, Dee Cesare V, Matthews SP, Nirujogi RS, Cole I, Hope A, Cunningham F, Toth R, Mukherjee R, Bojkova D, Gruber F, Gray D, Wyatt PG, Cinatl J, ... Dikic I, et al. Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. Plos One. 16: e0253364. PMID 34270554 DOI: 10.1371/journal.pone.0253364  0.766
2021 Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour AR, Shin D, Khan KS, Hei-Yin Cheung H, Wong KB, Ng W, Cinatl J, Geurink PP, van der Heden van Noort GJ, Rajalingam K, Ciesek S, Hummer G, ... Dikic I, et al. Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. The Journal of Biological Chemistry. 100925. PMID 34214498 DOI: 10.1016/j.jbc.2021.100925  0.752
2021 Gubas A, Dikic I. A Guide To… The regulation of selective autophagy receptors. The Febs Journal. PMID 33730405 DOI: 10.1111/febs.15824  0.313
2020 Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, ... ... Dikic I, et al. Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature. PMID 32726803 DOI: 10.1038/S41586-020-2601-5  0.769
2020 Maculins T, Garcia-Pardo J, Skenderovic A, Gebel J, Putyrski M, Vorobyov A, Busse P, Varga G, Kuzikov M, Zaliani A, Rahighi S, Schaeffer V, Parnham MJ, Sidhu SS, Ernst A, ... ... Dikic I, et al. Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chemical Biology. PMID 32726587 DOI: 10.1016/J.Chembiol.2020.07.010  0.639
2020 Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, ... ... Dikic I, et al. MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. The Embo Journal. e105696. PMID 32716134 DOI: 10.15252/Embj.2020105696  0.416
2020 Putyrski M, Vakhrusheva O, Bonn F, Guntur S, Vorobyov A, Brandts C, Dikic I, Ernst A. Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine. Frontiers in Cell and Developmental Biology. 8: 208. PMID 32296703 DOI: 10.3389/Fcell.2020.00208  0.664
2020 Tiku V, Tan MW, Dikic I. Mitochondrial Functions in Infection and Immunity. Trends in Cell Biology. 30: 263-275. PMID 32200805 DOI: 10.1016/J.Tcb.2020.01.006  0.303
2020 Maddi K, Sam DK, Bonn F, Prgomet S, Tulowetzke E, Akutsu M, Lopez-Mosqueda J, Dikic I. Wss1 Promotes Replication Stress Tolerance by Degrading Histones. Cell Reports. 30: 3117-3126.e4. PMID 32130911 DOI: 10.1016/J.Celrep.2020.02.018  0.314
2020 Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, Widera D, Fulda S, Wajant H, van Wijk SJL, Dikic I, Heilemann M. Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells. Science Signaling. 13. PMID 31937565 DOI: 10.1126/Scisignal.Aax5647  0.352
2019 Shin D, Mukherjee R, Liu Y, Gonzalez A, Bonn F, Liu Y, Rogov VV, Heinz M, Stolz A, Hummer G, Dötsch V, Luo ZQ, Bhogaraju S, Dikic I. Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB. Molecular Cell. PMID 31732457 DOI: 10.1016/J.Molcel.2019.10.019  0.794
2019 Pohl C, Dikic I. Cellular quality control by the ubiquitin-proteasome system and autophagy. Science (New York, N.Y.). 366: 818-822. PMID 31727826 DOI: 10.1126/Science.Aax3769  0.322
2019 Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G, Dikic I. TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. Embo Reports. e48317. PMID 31709703 DOI: 10.15252/Embr.201948317  0.34
2019 Hübner CA, Dikic I. ER-phagy and human diseases. Cell Death and Differentiation. PMID 31659280 DOI: 10.1038/S41418-019-0444-0  0.387
2019 Bhogaraju S, Bonn F, Mukherjee R, Adams M, Pfleiderer MM, Galej WP, Matkovic V, Lopez-Mosqueda J, Kalayil S, Shin D, Dikic I. Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin-catalysed glutamylation. Nature. PMID 31330532 DOI: 10.1038/S41586-019-1440-8  0.792
2019 Yuki KE, Marei H, Fiskin E, Eva MM, Gopal AA, Schwartzentruber JA, Majewski J, Cellier M, Mandl JN, Vidal SM, Malo D, Dikic I. CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection. Nature Microbiology. PMID 31285585 DOI: 10.1038/S41564-019-0484-8  0.366
2019 Herhaus L, van den Bedem H, Tang S, Maslennikov I, Wakatsuki S, Dikic I, Rahighi S. Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains. Journal of Molecular Biology. PMID 31247202 DOI: 10.2210/Pdb6N5M/Pdb  0.357
2019 Bhaskara RM, Grumati P, Garcia-Pardo J, Kalayil S, Covarrubias-Pinto A, Chen W, Kudryashev M, Dikic I, Hummer G. Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy. Nature Communications. 10: 2370. PMID 31147549 DOI: 10.1038/S41467-019-10345-3  0.326
2019 Mukherjee R, Dikic I. NIPSNAP Beacons in Mitophagy. Developmental Cell. 49: 503-505. PMID 31112696 DOI: 10.1016/J.Devcel.2019.05.008  0.753
2019 Huber J, Obata M, Gruber J, Akutsu M, Löhr F, Rogova N, Güntert P, Dikic I, Kirkin V, Komatsu M, Dötsch V, Rogov VV. An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy. PMID 30990354 DOI: 10.1080/15548627.2019.1606637  0.402
2019 Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, ... ... Dikic I, et al. Deubiquitinase USP10 regulates Notch signaling in the endothelium. Science (New York, N.Y.). 364: 188-193. PMID 30975888 DOI: 10.1126/Science.Aat0778  0.604
2019 Tiku V, Dikic I. Autophagy without conjugation. Nature Structural & Molecular Biology. PMID 30911186 DOI: 10.1038/S41594-019-0207-0  0.401
2019 Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M. Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife. 8. PMID 30838976 DOI: 10.7554/Elife.42549  0.558
2019 van Wijk SJ, Fulda S, Dikic I, Heilemann M. Visualizing ubiquitination in mammalian cells. Embo Reports. 20. PMID 30665942 DOI: 10.15252/Embr.201846520  0.391
2019 Juretschke T, Beli P, Dikic I. Quantitative Phosphoproteomics of Selective Autophagy Receptors. Methods in Molecular Biology (Clifton, N.J.). 1880: 691-701. PMID 30610732 DOI: 10.1007/978-1-4939-8873-0_46  0.437
2019 Wegner M, Diehl V, Bittl V, Bruyn Rd, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M. Author response: Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome Elife. DOI: 10.7554/Elife.42549.044  0.53
2018 Forrester A, De Leonibus C, Grumati P, Fasana E, Piemontese M, Staiano L, Fregno I, Raimondi A, Marazza A, Bruno G, Iavazzo M, Intartaglia D, Seczynska M, van Anken E, Conte I, ... ... Dikic I, et al. A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex. The Embo Journal. PMID 30559329 DOI: 10.15252/Embj.201899847  0.381
2018 Nguyen TD, Shaid S, Vakhrusheva O, Koschade SE, Klann K, Thöken M, Baker F, Zhang J, Oellerich T, Sürün D, Derlet A, Haberbosch I, Eimer S, Osiewacz HD, Behrends C, ... ... Dikic I, et al. Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy. Blood. PMID 30498063 DOI: 10.1182/Blood-2018-02-833475  0.325
2018 Stolz A, Dikic I. Elusive mitochondrial connection to inflammation uncovered. Nature. 561: 185-186. PMID 30194366 DOI: 10.1038/D41586-018-05988-Z  0.753
2018 Grumati P, Dikic I, Stolz A. ER-phagy at a glance. Journal of Cell Science. 131. PMID 30177506 DOI: 10.1242/Jcs.217364  0.765
2018 Kalayil S, Bhogaraju S, Bonn F, Shin D, Liu Y, Gan N, Basquin J, Grumati P, Luo ZQ, Dikic I. Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination. Nature. PMID 29795347 DOI: 10.1038/S41586-018-0145-8  0.41
2018 Dikic I, Elazar Z. Mechanism and medical implications of mammalian autophagy. Nature Reviews. Molecular Cell Biology. PMID 29618831 DOI: 10.1038/S41580-018-0003-4  0.321
2018 Stolz A, Dikic I. Heterotypic Ubiquitin Chains: Seeing is Believing. Trends in Cell Biology. 28: 1-3. PMID 29191367 DOI: 10.1016/J.Tcb.2017.11.005  0.737
2018 Grumati P, Dikic I. Ubiquitin signaling and autophagy. The Journal of Biological Chemistry. 293: 5404-5413. PMID 29187595 DOI: 10.1074/Jbc.Tm117.000117  0.394
2018 Šprung M, Dikic I, Novak I. Flow Cytometer Monitoring of Bnip3- and Bnip3L/Nix-Dependent Mitophagy. Methods in Molecular Biology (Clifton, N.J.). 1759: 105-110. PMID 28324488 DOI: 10.1007/7651_2017_14  0.314
2017 Herhaus L, Dikic I. Regulation of Salmonella-host cell interactions via the ubiquitin system. International Journal of Medical Microbiology : Ijmm. PMID 29126744 DOI: 10.1016/J.Ijmm.2017.11.003  0.335
2017 Amstein L, Ackermann J, Scheidel J, Fulda S, Dikic I, Koch I. Manatee invariants reveal functional pathways in signaling networks. Bmc Systems Biology. 11: 72. PMID 28754124 DOI: 10.1186/S12918-017-0448-7  0.307
2017 Rogov VV, Stolz A, Ravicahandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG. Structural and functional analysis of the GABARAP interaction motif (GIM). Embo Reports. PMID 28655748 DOI: 10.15252/Embr.201643587  0.753
2017 Grumati P, Morozzi G, Hölper S, Mari M, Harwardt MI, Yan R, Müller S, Reggiori F, Heilemann M, Dikic I. Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy. Elife. 6. PMID 28617241 DOI: 10.7554/Elife.25555  0.389
2017 Sakamaki JI, Wilkinson S, Hahn M, Tasdemir N, O'Prey J, Clark W, Hedley A, Nixon C, Long JS, New M, Van Acker T, Tooze SA, Lowe SW, Dikic I, Ryan KM. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Molecular Cell. 66: 517-532.e9. PMID 28525743 DOI: 10.1016/J.Molcel.2017.04.027  0.357
2017 van Wijk SJL, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, Grumati P, Kaulich M, Sou YS, Komatsu M, Greten FR, Fulda S, Heilemann M, Dikic I. Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation. Nature Microbiology. 2: 17066. PMID 28481361 DOI: 10.1038/Nmicrobiol.2017.66  0.37
2017 Dikic I. Proteasomal and Autophagic Degradation Systems. Annual Review of Biochemistry. 86: 193-224. PMID 28460188 DOI: 10.1146/Annurev-Biochem-061516-044908  0.338
2017 Rogov VV, Suzuki H, Marinković M, Lang V, Kato R, Kawasaki M, Buljubašić M, Šprung M, Rogova N, Wakatsuki S, Hamacher-Brady A, Dötsch V, Dikic I, Brady NR, Novak I. Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins. Scientific Reports. 7: 1131. PMID 28442745 DOI: 10.1038/S41598-017-01258-6  0.404
2017 Peng H, Yang J, Li G, You Q, Han W, Li T, Gao D, Xie X, Lee BH, Du J, Hou J, Zhang T, Rao H, Huang Y, Li Q, ... ... Dikic I, et al. Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell Research. PMID 28322253 DOI: 10.1038/Cr.2017.40  0.352
2017 Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch AK, Müller S, Dikic I, Mittelbronn M, Behrends C. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. Elife. 6. PMID 28195531 DOI: 10.7554/Elife.23063  0.375
2017 Fiskin E, Bhogaraju S, Herhaus L, Kalayil S, Hahn M, Dikic I. Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA. Nature Communications. 8: 14004. PMID 28084320 DOI: 10.1038/Ncomms14004  0.367
2017 Diamanti MA, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski AK, Richter B, Beli P, Hu Y, Saleh M, Mittelbronn M, Dikic I, Greten FR. IKKα controls ATG16L1 degradation to prevent ER stress during inflammation. The Journal of Experimental Medicine. PMID 28082356 DOI: 10.1084/Jem.20161867  0.356
2017 Seczynska M, Dikic I. Removing the waste bags: how p97 drives autophagy of lysosomes. The Embo Journal. 36: 129-131. PMID 27895087 DOI: 10.15252/Embj.201695950  0.317
2017 Grumati P, Morozzi G, Hölper S, Mari M, Harwardt MI, Yan R, Müller S, Reggiori F, Heilemann M, Dikic I. Author response: Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy Elife. DOI: 10.7554/Elife.25555.039  0.303
2016 Stolz A, Putyrski M, Kutle I, Huber J, Wang C, Major V, Sidhu SS, Youle RJ, Rogov VV, Dötsch V, Ernst A, Dikic I. Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins. The Embo Journal. PMID 28028054 DOI: 10.15252/Embj.201695063  0.766
2016 Bhogaraju S, Kalayil S, Liu Y, Bonn F, Colby T, Matic I, Dikic I. Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination. Cell. 167: 1636-1649.e13. PMID 27912065 DOI: 10.1016/J.Cell.2016.11.019  0.43
2016 Tooze SA, Dikic I. Autophagy Captures the Nobel Prize. Cell. 167: 1433-1435. PMID 27912049 DOI: 10.1016/J.Cell.2016.11.023  0.318
2016 Scheidel J, Amstein L, Ackermann J, Dikic I, Koch I. In Silico Knockout Studies of Xenophagic Capturing of Salmonella. Plos Computational Biology. 12: e1005200. PMID 27906974 DOI: 10.1371/Journal.Pcbi.1005200  0.379
2016 Lopez-Mosqueda J, Maddi K, Prgomet S, Kalayil S, Marinovic-Terzic I, Terzic J, Dikic I. SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks. Elife. 5. PMID 27852435 DOI: 10.7554/Elife.21491  0.303
2016 Hoeller D, Dikic I. How the proteasome is degraded. Proceedings of the National Academy of Sciences of the United States of America. 113: 13266-13268. PMID 27837026 DOI: 10.1073/Pnas.1616535113  0.441
2016 Fiskin E, Bionda T, Dikic I, Behrends C. Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection. Molecular Cell. 62: 967-981. PMID 27211868 DOI: 10.1016/J.Molcel.2016.04.015  0.359
2016 Bhogaraju S, Dikic I. Cell biology: Ubiquitination without E1 and E2 enzymes. Nature. 533: 43-4. PMID 27096359 DOI: 10.1038/Nature17888  0.333
2016 Suzuki N, Rohaim A, Kato R, Dikic I, Wakatsuki S, Kawasaki M. A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1. The Febs Journal. PMID 27062441 DOI: 10.1111/Febs.13734  0.344
2016 Richter B, Sliter DA, Herhaus L, Stolz A, Wang C, Beli P, Zaffagnini G, Wild P, Martens S, Wagner SA, Youle RJ, Dikic I. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035970 DOI: 10.1073/Pnas.1523926113  0.78
2016 Baccarini M, Dikic I. Editorial overview: Cell regulation. Current Opinion in Cell Biology. 39: iv-vi. PMID 27017261 DOI: 10.1016/J.Ceb.2016.03.010  0.315
2016 Nastase MV, Zeng-Brouwers J, Frey H, Hsieh LT, Poluzzi C, Beckmann J, Schroeder N, Pfeilschifter J, Lopez-Mosqueda J, Mersmann J, Ikeda F, Iozzo RV, Dikic I, Schaefer L. An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis. The American Journal of Pathology. 186: 1206-20. PMID 26968342 DOI: 10.1016/J.Ajpath.2015.12.026  0.355
2016 Maculins T, Fiskin E, Bhogaraju S, Dikic I. Bacteria-host relationship: ubiquitin ligases as weapons of invasion. Cell Research. 26: 499-510. PMID 26964724 DOI: 10.1038/Cr.2016.30  0.337
2016 Jennewein L, Ronellenfitsch MW, Antonietti P, Ilina EI, Jung J, Stadel D, Flohr LM, Zinke J, von Renesse J, Drott U, Baumgarten P, Braczynski AK, Penski C, Burger MC, Theurillat JP, ... ... Dikic I, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. PMID 26956048 DOI: 10.18632/Oncotarget.7910  0.31
2016 Habisov S, Huber J, Ichimura Y, Akutsu M, Rogova N, Loehr F, McEwan DG, Johansen T, Dikic I, Doetsch V, Komatsu M, Rogov VV, Kirkin V. Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation. The Journal of Biological Chemistry. 291: 9025-9041. PMID 26929408 DOI: 10.1074/Jbc.M116.715474  0.439
2016 Rajalingam K, Dikic I. SnapShot: Expanding the Ubiquitin Code. Cell. 164: 1074-1074.e1. PMID 26919436 DOI: 10.1016/J.Cell.2016.02.019  0.404
2016 Akutsu M, Dikic I, Bremm A. Ubiquitin chain diversity at a glance. Journal of Cell Science. 129: 875-80. PMID 26906419 DOI: 10.1242/Jcs.183954  0.401
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Dikic I, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.346
2016 Khaminets A, Behl C, Dikic I. Ubiquitin-Dependent And Independent Signals In Selective Autophagy. Trends in Cell Biology. 26: 6-16. PMID 26437584 DOI: 10.1016/J.Tcb.2015.08.010  0.459
2016 Hoeller D, Dikic I. Regulation of ubiquitin receptors by coupled monoubiquitination. Sub-Cellular Biochemistry. 54: 31-40. PMID 21222271 DOI: 10.1007/978-1-4419-6676-6_3  0.437
2015 Kern A, Dikic I, Behl C. The integration of autophagy and cellular trafficking pathways via RAB GAPs. Autophagy. 11: 2393-7. PMID 26565612 DOI: 10.1080/15548627.2015.1110668  0.403
2015 Herhaus L, Dikic I. Expanding the ubiquitin code through post-translational modification. Embo Reports. 16: 1071-83. PMID 26268526 DOI: 10.15252/Embr.201540891  0.414
2015 Leznicki P, Korac-Prlic J, Kliza K, Husnjak K, Nyathi Y, Dikic I, High S. Binding of SGTA to Rpn13 selectively modulates protein quality control. Journal of Cell Science. 128: 3187-96. PMID 26169395 DOI: 10.1242/Jcs.165209  0.406
2015 Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, ... ... Dikic I, et al. Regulation of endoplasmic reticulum turnover by selective autophagy. Nature. 522: 354-8. PMID 26040720 DOI: 10.1038/Nature14498  0.773
2015 McEwan DG, Dikic I. PLEKHM1: Adapting to life at the lysosome. Autophagy. 11: 720-2. PMID 25905573 DOI: 10.1080/15548627.2015.1034419  0.422
2015 McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon FP, Franz-Wachtel M, Perdu B, Akutsu M, Habermann A, Kirchof A, Helfrich MH, Odgren PR, ... ... Dikic I, et al. PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection. Cell Host & Microbe. 17: 58-71. PMID 25500191 DOI: 10.1016/J.Chom.2014.11.011  0.385
2015 McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, ... ... Dikic I, et al. PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Molecular Cell. 57: 39-54. PMID 25498145 DOI: 10.1016/J.Molcel.2014.11.006  0.435
2014 McEwan DG, Dikic I. Cullins keep autophagy under control. Developmental Cell. 31: 675-6. PMID 25535915 DOI: 10.1016/J.Devcel.2014.12.010  0.385
2014 Stolz A, Dikic I. PINK1-PARKIN interplay: down to ubiquitin phosphorylation. Molecular Cell. 56: 341-2. PMID 25514179 DOI: 10.1016/J.Molcel.2014.10.022  0.754
2014 Spang N, Feldmann A, Huesmann H, Bekbulat F, Schmitt V, Hiebel C, Koziollek-Drechsler I, Clement AM, Moosmann B, Jung J, Behrends C, Dikic I, Kern A, Behl C. RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy. Autophagy. 10: 2297-309. PMID 25495476 DOI: 10.4161/15548627.2014.994359  0.402
2014 Kumari S, Redouane Y, Lopez-Mosqueda J, Shiraishi R, Romanowska M, Lutzmayer S, Kuiper J, Martinez C, Dikic I, Pasparakis M, Ikeda F. Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis. Elife. 3. PMID 25443631 DOI: 10.7554/Elife.03422  0.359
2014 Popovic D, Vucic D, Dikic I. Ubiquitination in disease pathogenesis and treatment. Nature Medicine. 20: 1242-53. PMID 25375928 DOI: 10.1038/Nm.3739  0.319
2014 Dikic I, Bremm A. DUBs counteract parkin for efficient mitophagy. The Embo Journal. 33: 2442-3. PMID 25274967 DOI: 10.15252/Embj.201490101  0.347
2014 Stolz A, Ernst A, Dikic I. Cargo recognition and trafficking in selective autophagy. Nature Cell Biology. 16: 495-501. PMID 24875736 DOI: 10.1038/Ncb2979  0.776
2014 López-Mosqueda J, Dikic I. Deciphering functions of branched ubiquitin chains. Cell. 157: 767-9. PMID 24813601 DOI: 10.1016/J.Cell.2014.04.026  0.363
2014 Gomes LC, Dikic I. Autophagy in antimicrobial immunity. Molecular Cell. 54: 224-33. PMID 24766886 DOI: 10.1016/J.Molcel.2014.03.009  0.342
2014 Schaeffer V, Akutsu M, Olma MH, Gomes LC, Kawasaki M, Dikic I. Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling. Molecular Cell. 54: 349-61. PMID 24726327 DOI: 10.1016/J.Molcel.2014.03.016  0.42
2014 Grumati P, Dikic I. Germline polymorphisms in RNF31 regulate linear ubiquitination and oncogenic signaling. Cancer Discovery. 4: 394-6. PMID 24706658 DOI: 10.1158/2159-8290.Cd-14-0177  0.332
2014 Tufar P, Rahighi S, Kraas FI, Kirchner DK, Löhr F, Henrich E, Köpke J, Dikic I, Güntert P, Marahiel MA, Dötsch V. Crystal structure of a PCP/Sfp complex reveals the structural basis for carrier protein posttranslational modification. Chemistry & Biology. 21: 552-62. PMID 24704508 DOI: 10.1016/J.Chembiol.2014.02.014  0.355
2014 Popovic D, Dikic I. TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy. Embo Reports. 15: 392-401. PMID 24603492 DOI: 10.1002/Embr.201337995  0.384
2014 Piper RC, Dikic I, Lukacs GL. Ubiquitin-dependent sorting in endocytosis. Cold Spring Harbor Perspectives in Biology. 6. PMID 24384571 DOI: 10.1101/Cshperspect.A016808  0.389
2014 Wild P, McEwan DG, Dikic I. The LC3 interactome at a glance. Journal of Cell Science. 127: 3-9. PMID 24345374 DOI: 10.1242/Jcs.140426  0.438
2013 Stieglitz B, Rana RR, Koliopoulos MG, Morris-Davies AC, Schaeffer V, Christodoulou E, Howell S, Brown NR, Dikic I, Rittinger K. Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature. 503: 422-6. PMID 24141947 DOI: 10.1038/Nature12638  0.364
2013 van Wijk SJ, Fiškin E, Dikic I. Selective monitoring of ubiquitin signals with genetically encoded ubiquitin chain-specific sensors. Nature Protocols. 8: 1449-58. PMID 23807287 DOI: 10.1038/Nprot.2013.089  0.348
2013 Rogov VV, Suzuki H, Fiskin E, Wild P, Kniss A, Rozenknop A, Kato R, Kawasaki M, McEwan DG, Löhr F, Güntert P, Dikic I, Wakatsuki S, Dötsch V. Structural basis for phosphorylation-triggered autophagic clearance of Salmonella. The Biochemical Journal. 454: 459-66. PMID 23805866 DOI: 10.1042/Bj20121907  0.415
2013 Carroll B, Mohd-Naim N, Maximiano F, Frasa MA, McCormack J, Finelli M, Thoresen SB, Perdios L, Daigaku R, Francis RE, Futter C, Dikic I, Braga VM. The TBC/RabGAP Armus coordinates Rac1 and Rab7 functions during autophagy. Developmental Cell. 25: 15-28. PMID 23562278 DOI: 10.1016/J.Devcel.2013.03.005  0.403
2013 Fiškin E, Dikic I. Parkin promotes cell survival via linear ubiquitination. The Embo Journal. 32: 1072-4. PMID 23531882 DOI: 10.1038/Emboj.2013.70  0.31
2013 Zhu Y, Massen S, Terenzio M, Lang V, Chen-Lindner S, Eils R, Novak I, Dikic I, Hamacher-Brady A, Brady NR. Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis. The Journal of Biological Chemistry. 288: 1099-113. PMID 23209295 DOI: 10.1074/Jbc.M112.399345  0.415
2013 Korac J, Schaeffer V, Kovacevic I, Clement AM, Jungblut B, Behl C, Terzic J, Dikic I. Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. Journal of Cell Science. 126: 580-92. PMID 23178947 DOI: 10.1242/Jcs.114926  0.378
2013 Haglund K, Dikic I. The role of ubiquitylation in receptor endocytosis and endosomal sorting. Journal of Cell Science. 125: 265-75. PMID 22357968 DOI: 10.1242/Jcs.091280  0.41
2012 Verhelst K, Carpentier I, Kreike M, Meloni L, Verstrepen L, Kensche T, Dikic I, Beyaert R. A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7. The Embo Journal. 31: 3845-55. PMID 23032186 DOI: 10.1038/Emboj.2012.240  0.322
2012 Pohl C, Dikic I. Fighting mycobacteria through ISGylation. Embo Reports. 13: 872-3. PMID 22940737 DOI: 10.1038/Embor.2012.129  0.391
2012 Belgnaoui SM, Paz S, Samuel S, Goulet ML, Sun Q, Kikkert M, Iwai K, Dikic I, Hiscott J, Lin R. Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex. Cell Host & Microbe. 12: 211-22. PMID 22901541 DOI: 10.1016/J.Chom.2012.06.009  0.377
2012 van Wijk SJ, Fiskin E, Putyrski M, Pampaloni F, Hou J, Wild P, Kensche T, Grecco HE, Bastiaens P, Dikic I. Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells. Molecular Cell. 47: 797-809. PMID 22819327 DOI: 10.1016/J.Molcel.2012.06.017  0.325
2012 Fulda S, Rajalingam K, Dikic I. Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications. Embo Molecular Medicine. 4: 545-56. PMID 22730341 DOI: 10.1002/Emmm.201100707  0.376
2012 Shaid S, Brandts CH, Serve H, Dikic I. Ubiquitination and selective autophagy. Cell Death and Differentiation. 20: 21-30. PMID 22722335 DOI: 10.1038/Cdd.2012.72  0.414
2012 Kensche T, Tokunaga F, Ikeda F, Goto E, Iwai K, Dikic I. Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB. The Journal of Biological Chemistry. 287: 23626-34. PMID 22605335 DOI: 10.1074/Jbc.M112.347195  0.374
2012 Rahighi S, Dikic I. Selectivity of the ubiquitin-binding modules. Febs Letters. 586: 2705-10. PMID 22569095 DOI: 10.1016/J.Febslet.2012.04.053  0.421
2012 Stieglitz B, Haire LF, Dikic I, Rittinger K. Structural analysis of SHARPIN, a subunit of a large multi-protein E3 ubiquitin ligase, reveals a novel dimerization function for the pleckstrin homology superfold. The Journal of Biological Chemistry. 287: 20823-9. PMID 22549881 DOI: 10.1074/Jbc.M112.359547  0.387
2012 Husnjak K, Dikic I. Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. Annual Review of Biochemistry. 81: 291-322. PMID 22482907 DOI: 10.1146/Annurev-Biochem-051810-094654  0.47
2012 Rogov VV, Rozenknop A, Rogova NY, Löhr F, Tikole S, Jaravine V, Güntert P, Dikic I, Dötsch V. A universal expression tag for structural and functional studies of proteins. Chembiochem : a European Journal of Chemical Biology. 13: 959-63. PMID 22434781 DOI: 10.1002/Cbic.201200045  0.33
2012 Walczak H, Iwai K, Dikic I. Generation and physiological roles of linear ubiquitin chains. Bmc Biology. 10: 23. PMID 22420778 DOI: 10.1186/1741-7007-10-23  0.39
2012 Dikic I, Robertson M. Ubiquitin ligases and beyond. Bmc Biology. 10: 22. PMID 22420755 DOI: 10.1186/1741-7007-10-22  0.435
2012 Popovic D, Akutsu M, Novak I, Harper JW, Behrends C, Dikic I. Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers. Molecular and Cellular Biology. 32: 1733-44. PMID 22354992 DOI: 10.1128/MCB.06717-11  0.342
2012 Dikic I, Daly RJ. Signalling through the grapevine. Embo Reports. 13: 178-80. PMID 22354089 DOI: 10.1038/Embor.2012.16  0.308
2012 van Wijk SJ, Bienko M, Dikic I. Role of UbL family modifiers and their binding proteins in cell signaling. Methods in Molecular Biology (Clifton, N.J.). 832: 163-71. PMID 22350884 DOI: 10.1007/978-1-61779-474-2_11  0.426
2012 Rohaim A, Kawasaki M, Kato R, Dikic I, Wakatsuki S. Structure of a compact conformation of linear diubiquitin. Acta Crystallographica. Section D, Biological Crystallography. 68: 102-8. PMID 22281738 DOI: 10.1107/S0907444911051195  0.35
2012 Pareja F, Ferraro DA, Rubin C, Cohen-Dvashi H, Zhang F, Aulmann S, Ben-Chetrit N, Pines G, Navon R, Crosetto N, Köstler W, Carvalho S, Lavi S, Schmitt F, Dikic I, et al. Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression. Oncogene. 31: 4599-608. PMID 22179831 DOI: 10.1038/Onc.2011.587  0.545
2012 Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC. Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling. Nature Cell Biology. 14: 51-60. PMID 22138575 DOI: 10.1038/Ncb2386  0.375
2011 Rajalingam K, Dikic I. Healthy ageing through regulated proteostasis. The Embo Journal. 30: 2983-5. PMID 21811299 DOI: 10.1038/Emboj.2011.237  0.367
2011 Rozenknop A, Rogov VV, Rogova NY, Löhr F, Güntert P, Dikic I, Dötsch V. Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1. Journal of Molecular Biology. 410: 477-87. PMID 21620860 DOI: 10.1016/J.Jmb.2011.05.003  0.392
2011 Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D, Dikic I. Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science (New York, N.Y.). 333: 228-33. PMID 21617041 DOI: 10.1126/Science.1205405  0.454
2011 Ikeda F, Deribe YL, Skånland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, ... ... Dikic I, et al. SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature. 471: 637-41. PMID 21455181 DOI: 10.1038/Nature09814  0.391
2011 Grabbe C, Husnjak K, Dikic I. The spatial and temporal organization of ubiquitin networks. Nature Reviews. Molecular Cell Biology. 12: 295-307. PMID 21448225 DOI: 10.1038/Nrm3099  0.358
2011 Mendl N, Occhipinti A, Müller M, Wild P, Dikic I, Reichert AS. Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2. Journal of Cell Science. 124: 1339-50. PMID 21429936 DOI: 10.1242/Jcs.076406  0.346
2011 McEwan DG, Dikic I. The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation. Trends in Cell Biology. 21: 195-201. PMID 21277210 DOI: 10.1016/J.Tcb.2010.12.006  0.397
2011 Novak I, Dikic I. Autophagy receptors in developmental clearance of mitochondria. Autophagy. 7: 301-3. PMID 21206218 DOI: 10.4161/Auto.7.3.14509  0.369
2011 Ikeda F, Rahighi S, Wakatsuki S, Dikic I. Selective binding of linear ubiquitin chains to NEMO in NF-kappaB activation. Advances in Experimental Medicine and Biology. 691: 107-14. PMID 21153314 DOI: 10.1007/978-1-4419-6612-4_11  0.406
2010 Ikeda F, Crosetto N, Dikic I. What determines the specificity and outcomes of ubiquitin signaling? Cell. 143: 677-81. PMID 21111228 DOI: 10.1016/J.Cell.2010.10.026  0.379
2010 Kirkin V, Dikic I. Ubiquitin networks in cancer. Current Opinion in Genetics & Development. 21: 21-8. PMID 21071203 DOI: 10.1016/J.Gde.2010.10.004  0.38
2010 Suzuki N, Hiraki M, Yamada Y, Matsugaki N, Igarashi N, Kato R, Dikic I, Drew D, Iwata S, Wakatsuki S, Kawasaki M. Crystallization of small proteins assisted by green fluorescent protein. Acta Crystallographica. Section D, Biological Crystallography. 66: 1059-66. PMID 20944239 DOI: 10.1107/S0907444910032944  0.313
2010 Bethani I, Skånland SS, Dikic I, Acker-Palmer A. Spatial organization of transmembrane receptor signalling. The Embo Journal. 29: 2677-88. PMID 20717138 DOI: 10.1038/Emboj.2010.175  0.368
2010 Deribe YL, Pawson T, Dikic I. Post-translational modifications in signal integration. Nature Structural & Molecular Biology. 17: 666-72. PMID 20495563 DOI: 10.1038/Nsmb.1842  0.372
2010 Dikic I, Schmidt MHH. Notch: Implications of endogenous inhibitors for therapy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 481-487. PMID 20486134 DOI: 10.1002/Bies.200900140  0.368
2010 Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H. Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster. Current Biology : Cb. 20: 944-50. PMID 20451383 DOI: 10.1016/J.Cub.2010.03.068  0.317
2010 Dikic I, Johansen T, Kirkin V. Selective autophagy in cancer development and therapy. Cancer Research. 70: 3431-4. PMID 20424122 DOI: 10.1158/0008-5472.Can-09-4027  0.34
2010 Vivanco I, Rohle D, Versele M, Iwanami A, Kuga D, Oldrini B, Tanaka K, Dang J, Kubek S, Palaskas N, Hsueh T, Evans M, Mulholland D, Wolle D, Rajasekaran S, ... ... Dikic I, et al. The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation. Proceedings of the National Academy of Sciences of the United States of America. 107: 6459-64. PMID 20308550 DOI: 10.1073/Pnas.0911188107  0.334
2010 Bomar MG, D'Souza S, Bienko M, Dikic I, Walker GC, Zhou P. Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1. Molecular Cell. 37: 408-17. PMID 20159559 DOI: 10.1016/J.Molcel.2009.12.038  0.357
2010 Bienko M, Green CM, Sabbioneda S, Crosetto N, Matic I, Hibbert RG, Begovic T, Niimi A, Mann M, Lehmann AR, Dikic I. Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Molecular Cell. 37: 396-407. PMID 20159558 DOI: 10.1016/J.Molcel.2009.12.039  0.324
2010 Wild P, Dikic I. Mitochondria get a Parkin' ticket. Nature Cell Biology. 12: 104-6. PMID 20118996 DOI: 10.1038/Ncb0210-104  0.332
2010 Nagy V, Dikic I. Ubiquitin ligase complexes: from substrate selectivity to conjugational specificity. Biological Chemistry. 391: 163-9. PMID 20030582 DOI: 10.1515/Bc.2010.021  0.335
2010 Novak I, Kirkin V, McEwan DG, Zhang J, Wild P, Rozenknop A, Rogov V, Löhr F, Popovic D, Occhipinti A, Reichert AS, Terzic J, Dötsch V, Ney PA, Dikic I. Nix is a selective autophagy receptor for mitochondrial clearance. Embo Reports. 11: 45-51. PMID 20010802 DOI: 10.1038/Embor.2009.256  0.411
2009 Deribe YL, Wild P, Chandrashaker A, Curak J, Schmidt MH, Kalaidzidis Y, Milutinovic N, Kratchmarova I, Buerkle L, Fetchko MJ, Schmidt P, Kittanakom S, Brown KR, Jurisica I, Blagoev B, ... ... Dikic I, et al. Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6. Science Signaling. 2: ra84. PMID 20029029 DOI: 10.1126/Scisignal.2000576  0.402
2009 Dikic I, Dötsch V. Ubiquitin linkages make a difference. Nature Structural & Molecular Biology. 16: 1209-10. PMID 19956206 DOI: 10.1038/Nsmb1209-1209  0.382
2009 Dikic I, Wakatsuki S, Walters KJ. Ubiquitin-binding domains - from structures to functions. Nature Reviews. Molecular Cell Biology. 10: 659-71. PMID 19773779 DOI: 10.1038/Nrm2767  0.386
2009 Schmidt MHH, Bicker F, Nikolic I, Meister J, Babuke T, Picuric S, Müller-Esterl W, Plate KH, Dikic I. Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal. Nature Cell Biology. 11: 873-80. PMID 19503073 DOI: 10.1038/Ncb1896  0.363
2009 Lamark T, Kirkin V, Dikic I, Johansen T. NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets. Cell Cycle (Georgetown, Tex.). 8: 1986-90. PMID 19502794 DOI: 10.4161/Cc.8.13.8892  0.414
2009 Kirkin V, McEwan DG, Novak I, Dikic I. A role for ubiquitin in selective autophagy. Molecular Cell. 34: 259-69. PMID 19450525 DOI: 10.1016/J.Molcel.2009.04.026  0.442
2009 Kirkin V, Lamark T, Johansen T, Dikic I. NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets. Autophagy. 5: 732-3. PMID 19398892 DOI: 10.4161/Auto.5.5.8566  0.424
2009 Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R, Kensche T, Uejima T, Bloor S, Komander D, Randow F, Wakatsuki S, Dikic I. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell. 136: 1098-109. PMID 19303852 DOI: 10.1016/J.Cell.2009.03.007  0.342
2009 Grabbe C, Dikic I. Functional roles of ubiquitin-like domain (ULD) and ubiquitin-binding domain (UBD) containing proteins. Chemical Reviews. 109: 1481-94. PMID 19253967 DOI: 10.1021/Cr800413P  0.358
2009 Kirkin V, Lamark T, Sou YS, Bjørkøy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Øvervatn A, Ishii T, Elazar Z, ... ... Dikic I, et al. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Molecular Cell. 33: 505-16. PMID 19250911 DOI: 10.1016/J.Molcel.2009.01.020  0.411
2009 Scharner D, Rössig L, Carmona G, Chavakis E, Urbich C, Fischer A, Kang TB, Wallach D, Chiang YJ, Deribe YL, Dikic I, Zeiher AM, Dimmeler S. Caspase-8 is involved in neovascularization-promoting progenitor cell functions. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 571-8. PMID 19122169 DOI: 10.1161/Atvbaha.108.182006  0.303
2009 Rajalingam K, Dikic I. Inhibitors of apoptosis catch ubiquitin. The Biochemical Journal. 417: e1-3. PMID 19061481 DOI: 10.1042/Bj20082215  0.382
2008 Crosetto N, Bienko M, Hibbert RG, Perica T, Ambrogio C, Kensche T, Hofmann K, Sixma TK, Dikic I. Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner. The Journal of Biological Chemistry. 283: 35173-85. PMID 18842586 DOI: 10.1074/Jbc.M803219200  0.377
2008 Nonis D, Schmidt MH, van de Loo S, Eich F, Dikic I, Nowock J, Auburger G. Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking. Cellular Signalling. 20: 1725-39. PMID 18602463 DOI: 10.1016/J.Cellsig.2008.05.018  0.386
2008 Ikeda F, Dikic I. Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series. Embo Reports. 9: 536-42. PMID 18516089 DOI: 10.1038/Embor.2008.93  0.416
2008 Schreiner P, Chen X, Husnjak K, Randles L, Zhang N, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M. Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature. 453: 548-52. PMID 18497827 DOI: 10.1038/Nature06924  0.436
2008 Husnjak K, Elsasser S, Zhang N, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D, Dikic I. Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature. 453: 481-8. PMID 18497817 DOI: 10.1038/Nature06926  0.42
2008 Schmidt-Glenewinkel H, Vacheva I, Hoeller D, Dikic I, Eils R. An ultrasensitive sorting mechanism for EGF receptor endocytosis. Bmc Systems Biology. 2: 32. PMID 18394191 DOI: 10.1186/1752-0509-2-32  0.324
2008 Marafioti T, Paterson JC, Ballabio E, Reichard KK, Tedoldi S, Hollowood K, Dictor M, Hansmann ML, Pileri SA, Dyer MJ, Sozzani S, Dikic I, Shaw AS, Petrella T, Stein H, et al. Novel markers of normal and neoplastic human plasmacytoid dendritic cells. Blood. 111: 3778-92. PMID 18218851 DOI: 10.1182/Blood-2007-10-117531  0.302
2008 Bloor S, Ryzhakov G, Wagner S, Butler PJ, Smith DL, Krumbach R, Dikic I, Randow F. Signal processing by its coil zipper domain activates IKK gamma. Proceedings of the National Academy of Sciences of the United States of America. 105: 1279-84. PMID 18216269 DOI: 10.1073/Pnas.0706552105  0.385
2008 Wagner S, Carpentier I, Rogov V, Kreike M, Ikeda F, Löhr F, Wu CJ, Ashwell JD, Dötsch V, Dikic I, Beyaert R. Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. Oncogene. 27: 3739-45. PMID 18212736 DOI: 10.1038/Sj.Onc.1211042  0.399
2008 Terzic J, Marinovic-Terzic I, Ikeda F, Dikic I. Ubiquitin signals in the NF-kappaB pathway. Biochemical Society Transactions. 35: 942-5. PMID 17956251 DOI: 10.1042/Bst0350942  0.343
2007 Guo C, Tang TS, Bienko M, Dikic I, Friedberg EC. Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance. The Journal of Biological Chemistry. 283: 4658-64. PMID 18162470 DOI: 10.1074/Jbc.M709275200  0.371
2007 Raguz J, Wagner S, Dikic I, Hoeller D. Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases. Febs Letters. 581: 4767-72. PMID 17880946 DOI: 10.1016/J.Febslet.2007.08.077  0.402
2007 Ikeda F, Hecker CM, Rozenknop A, Nordmeier RD, Rogov V, Hofmann K, Akira S, Dötsch V, Dikic I. Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes Embo Journal. 26: 3451-3462. PMID 17599067 DOI: 10.1038/Sj.Emboj.7601773  0.386
2007 Hoeller D, Hecker CM, Wagner S, Rogov V, Dötsch V, Dikic I. E3-Independent Monoubiquitination of Ubiquitin-Binding Proteins Molecular Cell. 26: 891-898. PMID 17588522 DOI: 10.1016/J.Molcel.2007.05.014  0.393
2007 Dikic I, Schmidt MHH. Malfunctions within the Cbl interactome uncouple receptor tyrosine kinases from destructive transport. European Journal of Cell Biology. 86: 505-12. PMID 17553592 DOI: 10.1016/J.Ejcb.2007.04.005  0.403
2007 Sargin B, Choudhary C, Crosetto N, Schmidt MH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwäble J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, ... ... Dikic I, et al. Flt3-dependent transformation by inactivating c-Cbl mutations in AML. Blood. 110: 1004-12. PMID 17446348 DOI: 10.1182/Blood-2007-01-066076  0.354
2007 Kirkin V, Dikic I. Role of ubiquitin- and Ubl-binding proteins in cell signaling. Current Opinion in Cell Biology. 19: 199-205. PMID 17303403 DOI: 10.1016/J.Ceb.2007.02.002  0.459
2007 Tossidou I, Kardinal C, Peters I, Kriz W, Shaw A, Dikic I, Tkachuk S, Dumler I, Haller H, Schiffer M. CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes Journal of Biological Chemistry. 282: 7457-7464. PMID 17213204 DOI: 10.1074/Jbc.M608519200  0.397
2007 Crosetto N, Bienko M, Dikic I. Ubiquitin hubs in oncogenic networks. Molecular Cancer Research : McR. 4: 899-904. PMID 17189380 DOI: 10.1158/1541-7786.Mcr-06-0328  0.392
2007 Schmidt MHH, Dikic I. The Cbl interactome and its functions. Nature Reviews. Molecular Cell Biology. 6: 907-18. PMID 16227975 DOI: 10.1038/Nrm1762  0.381
2006 Schmidt MHH, Dikic I. Ubiquitin and NEDD8: brothers in arms. Science's Stke : Signal Transduction Knowledge Environment. 2006: .pe50. PMID 17119158 DOI: 10.1126/Stke.3622006Pe50  0.449
2006 Dikic I, Crosetto N, Calatroni S, Bernasconi P. Targeting ubiquitin in cancers. European Journal of Cancer (Oxford, England : 1990). 42: 3095-102. PMID 17084074 DOI: 10.1016/J.Ejca.2006.05.041  0.416
2006 Moncalián G, Cárdenes N, Deribe YL, Spínola-Amilibia M, Dikic I, Bravo J. Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain. The Journal of Biological Chemistry. 281: 38845-53. PMID 17020880 DOI: 10.1074/Jbc.M606411200  0.345
2006 Hoeller D, Hecker CM, Dikic I. Ubiquitin and ubiquitin-like proteins in cancer pathogenesis. Nature Reviews. Cancer. 6: 776-88. PMID 16990855 DOI: 10.1038/Nrc1994  0.414
2006 Guo C, Tang TS, Bienko M, Parker JL, Bielen AB, Sonoda E, Takeda S, Ulrich HD, Dikic I, Friedberg EC. Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage. Molecular and Cellular Biology. 26: 8892-900. PMID 16982685 DOI: 10.1128/Mcb.01118-06  0.342
2006 Husnjak K, Dikic I. EGFR trafficking: parkin' in a jam. Nature Cell Biology. 8: 787-8. PMID 16880810 DOI: 10.1038/Ncb0806-787  0.416
2006 Seet BT, Dikic I, Zhou MM, Pawson T. Reading protein modifications with interaction domains. Nature Reviews. Molecular Cell Biology. 7: 473-83. PMID 16829979 DOI: 10.1038/Nrm1960  0.377
2006 Schmidt MHH, Dikic I. Assays to monitor degradation of the EGF receptor. Methods in Molecular Biology (Clifton, N.J.). 327: 131-8. PMID 16780217 DOI: 10.1385/1-59745-012-X:131  0.347
2006 Ikeda F, Dikic I. CYLD in ubiquitin signaling and tumor pathogenesis. Cell. 125: 643-5. PMID 16713556 DOI: 10.1016/J.Cell.2006.05.003  0.322
2006 Hecker CM, Rabiller M, Haglund K, Bayer P, Dikic I. Specification of SUMO1- and SUMO2-interacting motifs Journal of Biological Chemistry. 281: 16117-16127. PMID 16524884 DOI: 10.1074/Jbc.M512757200  0.374
2006 Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I. Regulation of ubiquitin-binding proteins by monoubiquitination. Nature Cell Biology. 8: 163-9. PMID 16429130 DOI: 10.1038/Ncb1354  0.456
2006 Schmidt MHH, Husnjak K, Szymkiewicz I, Haglund K, Dikic I. Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix. Oncogene. 25: 3071-8. PMID 16407834 DOI: 10.1038/Sj.Onc.1209329  0.438
2006 Katic M, Bosnjak B, Gall-Troselj K, Dikic I, Pavelic K. A clinoptilolite effect on cell media and the consequent effects on tumor cells in vitro. Frontiers in Bioscience : a Journal and Virtual Library. 11: 1722-32. PMID 16368551 DOI: 10.2741/1918  0.33
2005 Bienko M, Green CM, Crosetto N, Rudolf F, Zapart G, Coull B, Kannouche P, Wider G, Peter M, Lehmann AR, Hofmann K, Dikic I. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science (New York, N.Y.). 310: 1821-4. PMID 16357261 DOI: 10.1126/Science.1120615  0.367
2005 Aissouni Y, Zapart G, Iovanna JL, Dikic I, Soubeyran P. CIN85 regulates the ability of MEKK4 to activate the p38 MAP kinase pathway. Biochemical and Biophysical Research Communications. 338: 808-14. PMID 16256071 DOI: 10.1016/J.Bbrc.2005.10.032  0.422
2005 Jozic D, Cárdenes N, Deribe YL, Moncalián G, Hoeller D, Groemping Y, Dikic I, Rittinger K, Bravo J. Cbl promotes clustering of endocytic adaptor proteins. Nature Structural & Molecular Biology. 12: 972-9. PMID 16228008 DOI: 10.1038/Nsmb1000  0.383
2005 Molfetta R, Belleudi F, Peruzzi G, Morrone S, Leone L, Dikic I, Piccoli M, Frati L, Torrisi MR, Santoni A, Paolini R. CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: a new molecular mechanism to dampen mast cell function. Journal of Immunology (Baltimore, Md. : 1950). 175: 4208-16. PMID 16177060 DOI: 10.4049/Jimmunol.175.7.4208  0.403
2005 Haglund K, Dikic I. Ubiquitylation and cell signaling. The Embo Journal. 24: 3353-9. PMID 16148945 DOI: 10.1038/Sj.Emboj.7600808  0.43
2005 Eckerdt F, Yuan J, Saxena K, Martin B, Kappel S, Lindenau C, Kramer A, Naumann S, Daum S, Fischer G, Dikic I, Kaufmann M, Strebhardt K. Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells. The Journal of Biological Chemistry. 280: 36575-83. PMID 16118204 DOI: 10.1074/Jbc.M504548200  0.395
2005 Haglund K, Schmidt MH, Wong ES, Guy GR, Dikic I. Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation. Embo Reports. 6: 635-41. PMID 15962011 DOI: 10.1038/Sj.Embor.7400453  0.404
2005 Crosetto N, Tikkanen R, Dikic I. Oncogenic breakdowns in endocytic adaptor proteins. Febs Letters. 579: 3231-8. PMID 15943966 DOI: 10.1016/J.Febslet.2005.03.029  0.427
2005 Hoeller D, Volarevic S, Dikic I. Compartmentalization of growth factor receptor signalling. Current Opinion in Cell Biology. 17: 107-11. PMID 15780584 DOI: 10.1016/J.Ceb.2005.01.001  0.381
2005 Shimokawa N, Dikic I, Sugama S, Koibuchi N. Molecular responses to acidosis of central chemosensitive neurons in brain. Cellular Signalling. 17: 799-808. PMID 15763422 DOI: 10.1016/J.Cellsig.2005.01.004  0.343
2005 Banno Y, Ohguchi K, Matsumoto N, Koda M, Ueda M, Hara A, Dikic I, Nozawa Y. Implication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cells. The Journal of Biological Chemistry. 280: 16319-24. PMID 15705590 DOI: 10.1074/Jbc.M410903200  0.336
2005 Schmidt MH, Dikic I, Bögler O. Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities. The Journal of Biological Chemistry. 280: 3414-25. PMID 15557335 DOI: 10.1074/Jbc.M409839200  0.411
2005 Szymkiewicz I, Shupliakov O, Dikic I. Cargo- and compartment-selective endocytic scaffold proteins. The Biochemical Journal. 383: 1-11. PMID 15219178 DOI: 10.1042/Bj20040913  0.436
2005 Shimokawa N, Qiu CH, Seki T, Dikic I, Koibuchi N. Phosphorylation of JNK is involved in regulation of H(+)-induced c-Jun expression. Cellular Signalling. 16: 723-9. PMID 15093613 DOI: 10.1016/J.Cellsig.2003.11.005  0.327
2004 Schmidt MH, Hoeller D, Yu J, Furnari FB, Cavenee WK, Dikic I, Bögler O. Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. Molecular and Cellular Biology. 24: 8981-93. PMID 15456872 DOI: 10.1128/Mcb.24.20.8981-8993.2004  0.343
2004 Dikic I. ALIX-ing phospholipids with endosome biogenesis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 26: 604-7. PMID 15170857 DOI: 10.1002/Bies.20068  0.333
2004 Kowanetz K, Crosetto N, Haglund K, Schmidt MHH, Heldin CH, Dikic I. Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases. The Journal of Biological Chemistry. 279: 32786-95. PMID 15159412 DOI: 10.1074/Jbc.M403759200  0.427
2004 Szymkiewicz I, Destaing O, Jurdic P, Dikic I. SH3P2 in complex with Cbl and Src. Febs Letters. 565: 33-8. PMID 15135048 DOI: 10.1016/J.Febslet.2004.03.100  0.401
2004 Haglund K, Ivankovic-Dikic I, Shimokawa N, Kruh GD, Dikic I. Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites. Journal of Cell Science. 117: 2557-68. PMID 15128873 DOI: 10.1242/Jcs.01148  0.356
2004 Kowanetz K, Husnjak K, Höller D, Kowanetz M, Soubeyran P, Hirsch D, Schmidt MH, Pavelic K, De Camilli P, Randazzo PA, Dikic I. CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Molecular Biology of the Cell. 15: 3155-66. PMID 15090612 DOI: 10.1091/Mbc.E03-09-0683  0.448
2004 Höller D, Dikic I. Receptor endocytosis via ubiquitin-dependent and -independent pathways. Biochemical Pharmacology. 67: 1013-7. PMID 15006537 DOI: 10.1016/J.Bcp.2004.01.003  0.456
2004 Dikic I. Mechanisms controlling EGF receptor endocytosis and degradation. Biochemical Society Transactions. 31: 1178-81. PMID 14641021 DOI: 10.1042/Bst0311178  0.425
2004 Haglund K, Di Fiore PP, Dikic I. Distinct monoubiquitin signals in receptor endocytosis. Trends in Biochemical Sciences. 28: 598-603. PMID 14607090 DOI: 10.1016/J.Tibs.2003.09.005  0.442
2003 Kowanetz K, Terzic J, Dikic I. Dab2 links CIN85 with clathrin-mediated receptor internalization. Febs Letters. 554: 81-7. PMID 14596919 DOI: 10.1016/S0014-5793(03)01111-6  0.391
2003 Dikic I, Szymkiewicz I, Soubeyran P. Cbl signaling networks in the regulation of cell function. Cellular and Molecular Life Sciences : Cmls. 60: 1805-27. PMID 14523545 DOI: 10.1007/S00018-003-3029-4  0.403
2003 Kowanetz K, Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K, Taylor JD, Soubeyran P, Engstrom U, Ladbury JE, Dikic I. Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors. The Journal of Biological Chemistry. 278: 39735-46. PMID 12874286 DOI: 10.1074/Jbc.M304541200  0.4
2003 Haglund K, Sigismund S, Polo S, Szymkiewicz I, Di Fiore PP, Dikic I. Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nature Cell Biology. 5: 461-6. PMID 12717448 DOI: 10.1038/Ncb983  0.459
2003 Dikic I, Giordano S. Negative receptor signalling. Current Opinion in Cell Biology. 15: 128-35. PMID 12648667 DOI: 10.1016/S0955-0674(03)00004-8  0.428
2003 Piiper A, Lutz MP, Cramer H, Elez R, Kronenberger B, Dikic I, Müller-Esterl W, Zeuzem S. Protein kinase A mediates cAMP-induced tyrosine phosphorylation of the epidermal growth factor receptor. Biochemical and Biophysical Research Communications. 301: 848-54. PMID 12589790 DOI: 10.1016/S0006-291X(03)00055-X  0.356
2003 Soubeyran P, Barac A, Szymkiewicz I, Dikic I. Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl. The Biochemical Journal. 370: 29-34. PMID 12475393 DOI: 10.1042/Bj20021539  0.335
2002 Dikic I. CIN85/CMS family of adaptor molecules. Febs Letters. 529: 110-5. PMID 12354621 DOI: 10.1016/S0014-5793(02)03188-5  0.431
2002 Haglund K, Shimokawa N, Szymkiewicz I, Dikic I. Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 12191-6. PMID 12218189 DOI: 10.1073/Pnas.192462299  0.427
2002 Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, Cramer H, Müller-Esterl W, Zeuzem S. Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells. The Journal of Biological Chemistry. 277: 43623-30. PMID 12218049 DOI: 10.1074/Jbc.M203926200  0.379
2002 Szymkiewicz I, Kowanetz K, Soubeyran P, Dinarina A, Lipkowitz S, Dikic I. CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases Journal of Biological Chemistry. 277: 39666-39672. PMID 12177062 DOI: 10.1074/Jbc.M205535200  0.387
2002 Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature. 416: 183-7. PMID 11894095 DOI: 10.1038/416183A  0.4
2002 Sajan MP, Bandyopadhyay G, Kanoh Y, Standaert ML, Quon MJ, Reed BC, Dikic I, Farese RV. Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D. The Biochemical Journal. 362: 665-74. PMID 11879194 DOI: 10.1042/0264-6021:3620665  0.342
2002 Picascia A, Stanzione R, Chieffi P, Kisslinger A, Dikic I, Tramontano D. Proline-rich tyrosine kinase 2 regulates proliferation and differentiation of prostate cells. Molecular and Cellular Endocrinology. 186: 81-87. PMID 11850124 DOI: 10.1016/S0303-7207(01)00667-0  0.307
2002 Pizard A, Blaukat A, Michineau S, Dikic I, Müller-Esterl W, Alhenc-Gelas F, Rajerison RM. Palmitoylation of the human bradykinin B2 receptor influences ligand efficacy. Biochemistry. 40: 15743-51. PMID 11747451 DOI: 10.1021/Bi011600T  0.329
2001 Blaukat A, Pizard A, Breit A, Wernstedt C, Alhenc-Gelas F, Muller-Esterl W, Dikic I. Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function. The Journal of Biological Chemistry. 276: 40431-40. PMID 11517230 DOI: 10.1074/Jbc.M107024200  0.382
2001 Soubeyran P, Haglund K, Garcia S, Barth BU, Iovanna J, Dikic I. Homeobox gene Cdx1 regulates Ras, Rho and PI3 kinase pathways leading to transformation and tumorigenesis of intestinal epithelial cells. Oncogene. 20: 4180-7. PMID 11464284 DOI: 10.1038/Sj.Onc.1204551  0.332
2001 Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Quon MJ, Reed BC, Dikic I, Farese RV. Glucose activates protein kinase C-zeta /lambda through proline-rich tyrosine kinase-2, extracellular signal-regulated kinase, and phospholipase D: a novel mechanism for activating glucose transporter translocation. The Journal of Biological Chemistry. 276: 35537-45. PMID 11463795 DOI: 10.1074/Jbc.M106042200  0.303
2001 Blaukat A, Dikic I. Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway. Biological Chemistry. 382: 135-9. PMID 11258664 DOI: 10.1515/Bc.2001.020  0.382
2001 Ivankovic-Dikic I, Grönroos E, Blaukat A, Barth BU, Dikic I. Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins. Nature Cell Biology. 2: 574-81. PMID 10980697 DOI: 10.1038/35023515  0.403
2000 Blaukat A, Barac A, Cross MJ, Offermanns S, Dikic I. G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals. Molecular and Cellular Biology. 20: 6837-48. PMID 10958680 DOI: 10.1128/Mcb.20.18.6837-6848.2000  0.401
2000 Sasaki A, Yasukawa H, Shouda T, Kitamura T, Dikic I, Yoshimura A. CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2. The Journal of Biological Chemistry. 275: 29338-47. PMID 10882725 DOI: 10.1074/Jbc.M003456200  0.384
1999 Dikic I, Blaukat A. Protein tyrosine kinase-mediated pathways in G protein-coupled receptor signaling. Cell Biochemistry and Biophysics. 30: 369-87. PMID 10403057 DOI: 10.1007/Bf02738120  0.443
1999 Blaukat A, Pizard A, Rajerison RM, Alhenc-Gelas F, Müller-Esterl W, Dikic I. Activation of mitogen-activated protein kinase by the bradykinin B2 receptor is independent of receptor phosphorylation and phosphorylation-triggered internalization. Febs Letters. 451: 337-41. PMID 10371216 DOI: 10.1016/S0014-5793(99)00613-4  0.406
1999 Yamashita H, Avraham S, Jiang S, Dikic I, Avraham H. The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells. The Journal of Biological Chemistry. 274: 15059-65. PMID 10329710 DOI: 10.1074/Jbc.274.21.15059  0.407
1999 Blaukat A, Ivankovic-Dikic I, Grönroos E, Dolfi F, Tokiwa G, Vuori K, Dikic I. Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades. Journal of Biological Chemistry. 274: 14893-14901. PMID 10329689 DOI: 10.1074/Jbc.274.21.14893  0.408
1998 Dikic I, Dikic I, Schlessinger J. Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling. The Journal of Biological Chemistry. 273: 14301-8. PMID 9603937 DOI: 10.1074/Jbc.273.23.14301  0.641
1998 Miyazaki T, Takaoka A, Nogueira L, Dikic I, Fujii H, Tsujino S, Mitani Y, Maeda M, Schlessinger J, Taniguchi T. Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway. Genes & Development. 12: 770-5. PMID 9512511 DOI: 10.1101/Gad.12.6.770  0.603
1997 Davis CB, Dikic I, Unutmaz D, Hill CM, Arthos J, Siani MA, Thompson DA, Schlessinger J, Littman DR. Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5. The Journal of Experimental Medicine. 186: 1793-8. PMID 9362541 DOI: 10.1084/Jem.186.10.1793  0.606
1997 Qian D, Lev S, van Oers NS, Dikic I, Schlessinger J, Weiss A. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. The Journal of Experimental Medicine. 185: 1253-9. PMID 9104812 DOI: 10.1084/Jem.185.7.1253  0.757
1996 Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature. 383: 547-50. PMID 8849729 DOI: 10.1038/383547A0  0.794
1996 Tokiwa G, Dikic I, Lev S, Schlessinger J. Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science (New York, N.Y.). 273: 792-4. PMID 8670418 DOI: 10.1126/Science.273.5276.792  0.797
1996 Mohammadi M, Dikic I, Sorokin A, Burgess WH, Jaye M, Schlessinger J. Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. Molecular and Cellular Biology. 16: 977-89. PMID 8622701 DOI: 10.1128/Mcb.16.3.977  0.654
1995 Galisteo ML, Dikic I, Batzer AG, Langdon WY, Schlessinger J. Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. The Journal of Biological Chemistry. 270: 20242-5. PMID 7657591 DOI: 10.1074/Jbc.270.35.20242  0.64
1995 Dikic I, Batzer AG, Blaikie P, Obermeier A, Ullrich A, Schlessinger J, Margolis B. Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain. The Journal of Biological Chemistry. 270: 15125-9. PMID 7541035 DOI: 10.1074/Jbc.270.25.15125  0.651
1994 Dikic I, Schlessinger J, Lax I. PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Current Biology : Cb. 4: 702-8. PMID 7953556 DOI: 10.1016/S0960-9822(00)00155-X  0.596
1994 Spivak-Kroizman T, Lemmon MA, Dikic I, Ladbury JE, Pinchasi D, Huang J, Jaye M, Crumley G, Schlessinger J, Lax I. Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation. Cell. 79: 1015-24. PMID 7528103 DOI: 10.1016/0092-8674(94)90032-9  0.717
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