Year |
Citation |
Score |
2017 |
Krall EB, Wang B, Munoz DM, Ilic N, Raghavan S, Niederst MJ, Yu K, Ruddy DA, Aguirre AJ, Kim JW, Redig AJ, Gainor JF, Williams JA, Asara JM, Doench JG, et al. KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer. Elife. 6. PMID 28145866 DOI: 10.7554/Elife.18970 |
0.467 |
|
2014 |
Crystal AS, Shaw AT, Sequist LV, Friboulet L, Niederst MJ, Lockerman EL, Frias RL, Gainor JF, Amzallag A, Greninger P, Lee D, Kalsy A, Gomez-Caraballo M, Elamine L, Howe E, et al. Patient-derived models of acquired resistance can identify effective drug combinations for cancer. Science (New York, N.Y.). 346: 1480-6. PMID 25394791 DOI: 10.1126/Science.1254721 |
0.353 |
|
2014 |
Reyes G, Niederst M, Cohen-Katsenelson K, Stender JD, Kunkel MT, Chen M, Brognard J, Sierecki E, Gao T, Nowak DG, Trotman LC, Glass CK, Newton AC. Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Proceedings of the National Academy of Sciences of the United States of America. 111: E3957-65. PMID 25201979 DOI: 10.1073/Pnas.1404221111 |
0.719 |
|
2014 |
Niederst MJ, Benes CH. EMT twists the road to PI3K. Cancer Discovery. 4: 149-51. PMID 24501304 DOI: 10.1158/2159-8290.CD-13-1030 |
0.344 |
|
2013 |
Niederst MJ, Engelman JA. Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer. Science Signaling. 6: re6. PMID 24065147 DOI: 10.1126/scisignal.2004652 |
0.506 |
|
2013 |
O'Neill AK, Niederst MJ, Newton AC. Suppression of survival signalling pathways by the phosphatase PHLPP. The Febs Journal. 280: 572-83. PMID 22340730 DOI: 10.1111/J.1742-4658.2012.08537.X |
0.719 |
|
2012 |
O'Hayre M, Niederst M, Fecteau JF, Nguyen VM, Kipps TJ, Messmer D, Newton AC, Handel TM. Mechanisms and consequences of the loss of PHLPP1 phosphatase in chronic lymphocytic leukemia (CLL). Leukemia. 26: 1689-92. PMID 22237780 DOI: 10.1038/Leu.2012.6 |
0.669 |
|
2011 |
Warfel NA, Niederst M, Newton AC. Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2. The Journal of Biological Chemistry. 286: 39122-9. PMID 21908613 DOI: 10.1074/Jbc.M111.278747 |
0.735 |
|
2011 |
Warfel NA, Niederst M, Stevens MW, Brennan PM, Frame MC, Newton AC. Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt Journal of Biological Chemistry. 286: 19777-19788. PMID 21454620 DOI: 10.1074/Jbc.M111.237081 |
0.677 |
|
2009 |
Brognard J, Niederst M, Reyes G, Warfel N, Newton AC. Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C. The Journal of Biological Chemistry. 284: 15215-23. PMID 19324870 DOI: 10.1074/Jbc.M901468200 |
0.688 |
|
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