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Year Citation  Score
2020 Rodrigues MS, Ferreira C, Dias C, Pliássova A, Souza L, Ledo A, Laranjinha J, Cunha RA, Köfalvi A. An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease. The European Journal of Neuroscience. PMID 32813905 DOI: 10.1111/ejn.14944  0.72
2020 Ledo A, Fernandes E, Quintero JE, Gerhardt GA, Barbosa RM. Electrochemical Evaluation of a Multi-Site Clinical Depth Recording Electrode for Monitoring Cerebral Tissue Oxygen. Micromachines. 11. PMID 32605324 DOI: 10.3390/mi11070632  0.96
2020 Laranjinha J, Nunes C, Ledo A, Lourenço C, Rocha B, Barbosa RM. The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling. Neurochemical Research. PMID 32193753 DOI: 10.1007/s11064-020-03015-0  0.96
2019 Lourenço CF, Caetano M, Ledo A, Barbosa RM. Platinized carbon fiber-based glucose microbiosensor designed for metabolic studies in brain slices. Bioelectrochemistry (Amsterdam, Netherlands). 130: 107325. PMID 31295700 DOI: 10.1016/j.bioelechem.2019.06.010  0.96
2018 Lourenço CF, Ledo A, Caetano M, Barbosa RM, Laranjinha J. Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus. Frontiers in Physiology. 9: 913. PMID 30065657 DOI: 10.3389/fphys.2018.00913  0.96
2018 Ledo A, Barbosa RM, Laranjinha J. Modulation of Cellular Respiration by Endogenously Produced Nitric Oxide in Rat Hippocampal Slices. Methods in Molecular Biology (Clifton, N.J.). 1782: 89-107. PMID 29850995 DOI: 10.1007/978-1-4939-7831-1_5  0.96
2018 Dias C, Lourenço CF, Barbosa RM, Laranjinha J, Ledo A. Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Analytical Biochemistry. 551: 43-50. PMID 29753719 DOI: 10.1016/j.ab.2018.05.010  0.96
2018 Ferreira NR, Ledo A, Laranjinha J, Gerhardt GA, Barbosa RM. Simultaneous measurements of ascorbate and glutamate in vivo in the rat brain using carbon fiber nanocomposite sensors and microbiosensor arrays. Bioelectrochemistry (Amsterdam, Netherlands). 121: 142-150. PMID 29413864 DOI: 10.1016/j.bioelechem.2018.01.009  0.96
2017 Ledo A, Lourenço CF, Laranjinha J, Gerhardt GA, Barbosa RM. Combined in vivo Amperometric Oximetry and Electrophysiology in a Single Sensor - a Tool for Epilepsy Research. Analytical Chemistry. PMID 29067809 DOI: 10.1021/acs.analchem.7b03452  0.96
2017 Lourenço CF, Ledo A, Gerhardt GA, Laranjinha J, Barbosa RM. Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays. Scientific Reports. 7: 6764. PMID 28754993 DOI: 10.1038/s41598-017-07119-6  0.96
2017 Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration. Free Radical Biology & Medicine. 108: 668-682. PMID 28435052 DOI: 10.1016/j.freeradbiomed.2017.04.026  0.96
2017 Ledo A, Lourenço CF, Laranjinha J, Brett CM, Gerhardt GA, Barbosa RM. Ceramic-Based Multisite Platinum Microelectrode Arrays: Morphological Characteristics and Electrochemical Performance for Extracellular Oxygen Measurements in Brain Tissue. Analytical Chemistry. 89: 1674-1683. PMID 28208270 DOI: 10.1021/acs.analchem.6b03772  0.96
2017 Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling. Experimental Neurology. 291: 36-43. PMID 28161255 DOI: 10.1016/j.expneurol.2017.01.013  0.96
2016 Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A. Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiology of Aging. 46: 84-95. PMID 27460153 DOI: 10.1016/j.neurobiolaging.2016.06.012  0.96
2015 Lourenço CF, Ledo A, Dias C, Barbosa RM, Laranjinha J. Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Frontiers in Aging Neuroscience. 7: 103. PMID 26074816 DOI: 10.3389/fnagi.2015.00103  0.96
2015 Ledo A, Lourenço CF, Caetano M, Barbosa RM, Laranjinha J. Age-associated changes of nitric oxide concentration dynamics in the central nervous system of Fisher 344 rats. Cellular and Molecular Neurobiology. 35: 33-44. PMID 25274046 DOI: 10.1007/s10571-014-0115-0  0.96
2014 Dias C, Barbosa RM, Laranjinha J, Ledo A. Evaluation of Mitochondrial Function in the CNS of Rodent Models of Alzheimer's Disease - High Resolution Respirometry Applied to Acute Hippocampal Slices. Free Radical Biology & Medicine. 75: S37. PMID 26461355 DOI: 10.1016/j.freeradbiomed.2014.10.780  0.96
2012 Laranjinha J, Santos RM, Lourenço CF, Ledo A, Barbosa RM. Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling. Annals of the New York Academy of Sciences. 1259: 10-8. PMID 22758631 DOI: 10.1111/j.1749-6632.2012.06582.x  0.48
2012 Santos RM, Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration. International Journal of Cell Biology. 2012: 391914. PMID 22719764 DOI: 10.1155/2012/391914  0.48
2012 Ledo A, Barbosa RM, Laranjinha J. Modulation of cellular respiration by endogenously produced nitric oxide in rat hippocampal slices. Methods in Molecular Biology (Clifton, N.J.). 810: 73-88. PMID 22057561 DOI: 10.1007/978-1-61779-382-0_5  0.96
2010 Ledo A, Barbosa R, Cadenas E, Laranjinha J. Dynamic and interacting profiles of *NO and O2 in rat hippocampal slices. Free Radical Biology & Medicine. 48: 1044-50. PMID 20100565 DOI: 10.1016/j.freeradbiomed.2010.01.024  0.48
2007 Laranjinha J, Ledo A. Coordination of physiologic and toxic pathways in hippocampus by nitric oxide and mitochondria. Frontiers in Bioscience : a Journal and Virtual Library. 12: 1094-106. PMID 17127364  0.72
2005 Ledo A, Barbosa RM, Gerhardt GA, Cadenas E, Laranjinha J. Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 17483-8. PMID 16293699 DOI: 10.1073/pnas.0503624102  0.48
2004 Ledo A, Frade J, Barbosa RM, Laranjinha J. Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions. Molecular Aspects of Medicine. 25: 75-89. PMID 15051318 DOI: 10.1016/j.mam.2004.02.010  0.96
2002 Ledo A, Barbosa RM, Frade J, Laranjinha J. Nitric oxide monitoring in hippocampal brain slices using electrochemical methods. Methods in Enzymology. 359: 111-25. PMID 12481564  0.96
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