Rui Barbosa - Publications

Faculdade de Farmácia University of Coimbra, Coimbra, Coimbra, Portugal 

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ledo A, Fernandes E, Quintero JE, Gerhardt GA, Barbosa RM. Electrochemical Evaluation of a Multi-Site Clinical Depth Recording Electrode for Monitoring Cerebral Tissue Oxygen. Micromachines. 11. PMID 32605324 DOI: 10.3390/mi11070632  0.92
2020 Laranjinha J, Nunes C, Ledo A, Lourenço C, Rocha B, Barbosa RM. The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling. Neurochemical Research. PMID 32193753 DOI: 10.1007/s11064-020-03015-0  0.92
2019 Lourenço CF, Caetano M, Ledo A, Barbosa RM. Platinized carbon fiber-based glucose microbiosensor designed for metabolic studies in brain slices. Bioelectrochemistry (Amsterdam, Netherlands). 130: 107325. PMID 31295700 DOI: 10.1016/j.bioelechem.2019.06.010  0.92
2018 Lourenço CF, Ledo A, Caetano M, Barbosa RM, Laranjinha J. Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus. Frontiers in Physiology. 9: 913. PMID 30065657 DOI: 10.3389/fphys.2018.00913  0.92
2018 Ledo A, Barbosa RM, Laranjinha J. Modulation of Cellular Respiration by Endogenously Produced Nitric Oxide in Rat Hippocampal Slices. Methods in Molecular Biology (Clifton, N.J.). 1782: 89-107. PMID 29850995 DOI: 10.1007/978-1-4939-7831-1_5  0.92
2018 Dias C, Lourenço CF, Barbosa RM, Laranjinha J, Ledo A. Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Analytical Biochemistry. 551: 43-50. PMID 29753719 DOI: 10.1016/j.ab.2018.05.010  0.92
2018 Ferreira NR, Ledo A, Laranjinha J, Gerhardt GA, Barbosa RM. Simultaneous measurements of ascorbate and glutamate in vivo in the rat brain using carbon fiber nanocomposite sensors and microbiosensor arrays. Bioelectrochemistry (Amsterdam, Netherlands). 121: 142-150. PMID 29413864 DOI: 10.1016/j.bioelechem.2018.01.009  0.92
2017 Ledo A, Lourenço CF, Laranjinha J, Gerhardt GA, Barbosa RM. Combined in vivo Amperometric Oximetry and Electrophysiology in a Single Sensor - a Tool for Epilepsy Research. Analytical Chemistry. PMID 29067809 DOI: 10.1021/acs.analchem.7b03452  0.92
2017 Lourenço CF, Ledo A, Gerhardt GA, Laranjinha J, Barbosa RM. Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays. Scientific Reports. 7: 6764. PMID 28754993 DOI: 10.1038/s41598-017-07119-6  0.92
2017 Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, ... ... Barbosa RM, et al. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biology. 13: 94-162. PMID 28577489 DOI: 10.1016/j.redox.2017.05.007  0.92
2017 Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration. Free Radical Biology & Medicine. 108: 668-682. PMID 28435052 DOI: 10.1016/j.freeradbiomed.2017.04.026  0.92
2017 Ledo A, Lourenço CF, Laranjinha J, Brett CM, Gerhardt GA, Barbosa RM. Ceramic-Based Multisite Platinum Microelectrode Arrays: Morphological Characteristics and Electrochemical Performance for Extracellular Oxygen Measurements in Brain Tissue. Analytical Chemistry. 89: 1674-1683. PMID 28208270 DOI: 10.1021/acs.analchem.6b03772  0.92
2017 Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling. Experimental Neurology. 291: 36-43. PMID 28161255 DOI: 10.1016/j.expneurol.2017.01.013  0.92
2017 Nunes C, Almeida L, Barbosa RM, Laranjinha J. Luteolin suppresses the JAK/STAT pathway in a cellular model of intestinal inflammation. Food & Function. 8: 387-396. PMID 28067377 DOI: 10.1039/c6fo01529h  0.92
2016 Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A. Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiology of Aging. 46: 84-95. PMID 27460153 DOI: 10.1016/j.neurobiolaging.2016.06.012  0.92
2015 Lourenço CF, Ledo A, Dias C, Barbosa RM, Laranjinha J. Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Frontiers in Aging Neuroscience. 7: 103. PMID 26074816 DOI: 10.3389/fnagi.2015.00103  0.92
2015 Ferreira NR, Lourenço CF, Barbosa RM, Laranjinha J. Coupling of ascorbate and nitric oxide dynamics in vivo in the rat hippocampus upon glutamatergic neuronal stimulation: a novel functional interplay. Brain Research Bulletin. 114: 13-9. PMID 25783673 DOI: 10.1016/j.brainresbull.2015.03.002  0.92
2015 Santos RM, Laranjinha J, Barbosa RM, Sirota A. Simultaneous measurement of cholinergic tone and neuronal network dynamics in vivo in the rat brain using a novel choline oxidase based electrochemical biosensor. Biosensors & Bioelectronics. 69: 83-94. PMID 25706061 DOI: 10.1016/j.bios.2015.02.003  0.64
2015 Pereira C, Barbosa RM, Laranjinha J. Dietary nitrite induces nitrosation of the gastric mucosa: the protective action of the mucus and the modulatory effect of red wine. The Journal of Nutritional Biochemistry. 26: 476-83. PMID 25701398 DOI: 10.1016/j.jnutbio.2014.12.004  0.92
2015 Rocha BS, Gago B, Barbosa RM, Cavaleiro C, Laranjinha J. Ethyl nitrite is produced in the human stomach from dietary nitrate and ethanol, releasing nitric oxide at physiological pH: potential impact on gastric motility. Free Radical Biology & Medicine. 82: 160-6. PMID 25645954 DOI: 10.1016/j.freeradbiomed.2015.01.021  0.92
2015 Ledo A, Lourenço CF, Caetano M, Barbosa RM, Laranjinha J. Age-associated changes of nitric oxide concentration dynamics in the central nervous system of Fisher 344 rats. Cellular and Molecular Neurobiology. 35: 33-44. PMID 25274046 DOI: 10.1007/s10571-014-0115-0  0.92
2014 Dias C, Barbosa RM, Laranjinha J, Ledo A. Evaluation of Mitochondrial Function in the CNS of Rodent Models of Alzheimer's Disease - High Resolution Respirometry Applied to Acute Hippocampal Slices. Free Radical Biology & Medicine. 75: S37. PMID 26461355 DOI: 10.1016/j.freeradbiomed.2014.10.780  0.92
2014 Rocha B, Correia M, Barbosa R, Laranjinha J. A dietary-driven redox modulation of gut microbiome-host interactions: the rescue of epithelial barrier and mucus production during dysbiosis by dietary nitrate. Free Radical Biology & Medicine. 75: S36-7. PMID 26461352 DOI: 10.1016/j.freeradbiomed.2014.10.779  0.36
2014 Rocha BS, Nunes C, Pereira C, Barbosa RM, Laranjinha J. A shortcut to wide-ranging biological actions of dietary polyphenols: modulation of the nitrate-nitrite-nitric oxide pathway in the gut. Food & Function. 5: 1646-52. PMID 24912104 DOI: 10.1039/c4fo00124a  0.92
2014 Lourenço CF, Santos RM, Barbosa RM, Cadenas E, Radi R, Laranjinha J. Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide. Free Radical Biology & Medicine. 73: 421-9. PMID 24887095 DOI: 10.1016/j.freeradbiomed.2014.05.021  0.64
2013 Pereira C, Ferreira NR, Rocha BS, Barbosa RM, Laranjinha J. The redox interplay between nitrite and nitric oxide: From the gut to the brain. Redox Biology. 1: 276-84. PMID 24024161 DOI: 10.1016/j.redox.2013.04.004  0.92
2013 Santos RM, Rodrigues MS, Laranjinha J, Barbosa RM. Biomimetic sensor based on hemin/carbon nanotubes/chitosan modified microelectrode for nitric oxide measurement in the brain. Biosensors & Bioelectronics. 44: 152-9. PMID 23419387 DOI: 10.1016/j.bios.2013.01.015  0.64
2013 Rocha BS, Gago B, Barbosa RM, Lundberg JO, Mann GE, Radi R, Laranjinha J. Pepsin is nitrated in the rat stomach, acquiring antiulcerogenic activity: a novel interaction between dietary nitrate and gut proteins. Free Radical Biology & Medicine. 58: 26-34. PMID 23277149 DOI: 10.1016/j.freeradbiomed.2012.12.017  0.64
2013 Nunes C, Ferreira E, Freitas V, Almeida L, Barbosa RM, Laranjinha J. Intestinal anti-inflammatory activity of red wine extract: unveiling the mechanisms in colonic epithelial cells. Food & Function. 4: 373-83. PMID 23233037 DOI: 10.1039/c2fo30233k  0.92
2013 Figueiras E, Oliveira R, Lourenço CF, Campos R, Humeau-Heurtier A, Barbosa RM, Laranjinha J, Requicha Ferreira LF, de Mul FF. Self-mixing microprobe for monitoring microvascular perfusion in rat brain. Medical & Biological Engineering & Computing. 51: 103-12. PMID 23065628 DOI: 10.1007/s11517-012-0973-x  0.92
2012 Laranjinha J, Santos RM, Lourenço CF, Ledo A, Barbosa RM. Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling. Annals of the New York Academy of Sciences. 1259: 10-8. PMID 22758631 DOI: 10.1111/j.1749-6632.2012.06582.x  0.64
2012 Santos RM, Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration. International Journal of Cell Biology. 2012: 391914. PMID 22719764 DOI: 10.1155/2012/391914  0.64
2012 Rocha BS, Gago B, Barbosa RM, Lundberg JO, Radi R, Laranjinha J. Intragastric nitration by dietary nitrite: implications for modulation of protein and lipid signaling. Free Radical Biology & Medicine. 52: 693-698. PMID 22154654 DOI: 10.1016/j.freeradbiomed.2011.11.011  0.92
2011 Nunes C, Barbosa RM, Almeida L, Laranjinha J. Nitric oxide and DOPAC-induced cell death: from GSH depletion to mitochondrial energy crisis. Molecular and Cellular Neurosciences. 48: 94-103. PMID 21708261 DOI: 10.1016/j.mcn.2011.06.009  0.92
2011 Santos RM, Lourenço CF, Gerhardt GA, Cadenas E, Laranjinha J, Barbosa RM. Evidence for a pathway that facilitates nitric oxide diffusion in the brain. Neurochemistry International. 59: 90-6. PMID 21672575 DOI: 10.1016/j.neuint.2011.05.016  0.64
2011 Rocha BS, Gago B, Pereira C, Barbosa RM, Bartesaghi S, Lundberg JO, Radi R, Laranjinha J. Dietary nitrite in nitric oxide biology: a redox interplay with implications for pathophysiology and therapeutics. Current Drug Targets. 12: 1351-63. PMID 21443473  0.92
2011 Santos RM, Lourenço CF, Pomerleau F, Huettl P, Gerhardt GA, Laranjinha J, Barbosa RM. Brain nitric oxide inactivation is governed by the vasculature. Antioxidants & Redox Signaling. 14: 1011-21. PMID 20712398 DOI: 10.1089/ars.2010.3297  0.64
2011 Lourenço CF, Santos R, Barbosa RM, Gerhardt G, Cadenas E, Laranjinha J. In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus. Hippocampus. 21: 622-30. PMID 20169537 DOI: 10.1002/hipo.20774  0.64
2010 Ledo A, Barbosa R, Cadenas E, Laranjinha J. Dynamic and interacting profiles of *NO and O2 in rat hippocampal slices. Free Radical Biology & Medicine. 48: 1044-50. PMID 20100565 DOI: 10.1016/j.freeradbiomed.2010.01.024  0.64
2010 Rocha BS, Gago B, Barbosa RM, Laranjinha J. Diffusion of nitric oxide through the gastric wall upon reduction of nitrite by red wine: physiological impact. Nitric Oxide : Biology and Chemistry. 22: 235-41. PMID 20083218 DOI: 10.1016/j.niox.2010.01.003  0.92
2009 Rocha BS, Gago B, Barbosa RM, Laranjinha J. Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation. Toxicology. 265: 41-8. PMID 19778575 DOI: 10.1016/j.tox.2009.09.008  0.92
2008 Santos RM, Lourenço CF, Piedade AP, Andrews R, Pomerleau F, Huettl P, Gerhardt GA, Laranjinha J, Barbosa RM. A comparative study of carbon fiber-based microelectrodes for the measurement of nitric oxide in brain tissue. Biosensors & Bioelectronics. 24: 704-9. PMID 18657966 DOI: 10.1016/j.bios.2008.06.034  0.64
2008 Barbosa RM, Lourenço CF, Santos RM, Pomerleau F, Huettl P, Gerhardt GA, Laranjinha J. In vivo real-time measurement of nitric oxide in anesthetized rat brain. Methods in Enzymology. 441: 351-67. PMID 18554545 DOI: 10.1016/S0076-6879(08)01220-2  0.64
2008 Rosário LM, Barbosa RM, Antunes CM, Baldeiras IE, Silva AM, Tomé AR, Santos RM. Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K(ATP) channels. Endocrine Journal. 55: 639-50. PMID 18493109 DOI: JST.JSTAGE/endocrj/K07E-131  0.64
2008 Gago B, Nyström T, Cavaleiro C, Rocha BS, Barbosa RM, Laranjinha J, Lundberg JO. The potent vasodilator ethyl nitrite is formed upon reaction of nitrite and ethanol under gastric conditions. Free Radical Biology & Medicine. 45: 404-12. PMID 18482590 DOI: 10.1016/j.freeradbiomed.2008.04.027  0.92
2008 Lourenço CF, Gago B, Barbosa RM, de Freitas V, Laranjinha J. LDL isolated from plasma-loaded red wine procyanidins resist lipid oxidation and tocopherol depletion. Journal of Agricultural and Food Chemistry. 56: 3798-804. PMID 18454545 DOI: 10.1021/jf0733259  0.92
2008 Frade J, Pope S, Schmidt M, Dringen R, Barbosa R, Pocock J, Laranjinha J, Heales S. Glutamate induces release of glutathione from cultured rat astrocytes--a possible neuroprotective mechanism? Journal of Neurochemistry. 105: 1144-52. PMID 18182055 DOI: 10.1111/j.1471-4159.2008.05216.x  0.64
2007 Gago B, Lundberg JO, Barbosa RM, Laranjinha J. Red wine-dependent reduction of nitrite to nitric oxide in the stomach. Free Radical Biology & Medicine. 43: 1233-42. PMID 17893036 DOI: 10.1016/j.freeradbiomed.2007.06.007  0.92
2005 Ledo A, Barbosa RM, Gerhardt GA, Cadenas E, Laranjinha J. Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 17483-8. PMID 16293699 DOI: 10.1073/pnas.0503624102  0.64
2004 Ledo A, Frade J, Barbosa RM, Laranjinha J. Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions. Molecular Aspects of Medicine. 25: 75-89. PMID 15051318 DOI: 10.1016/j.mam.2004.02.010  0.92
2002 Ledo A, Barbosa RM, Frade J, Laranjinha J. Nitric oxide monitoring in hippocampal brain slices using electrochemical methods. Methods in Enzymology. 359: 111-25. PMID 12481564  0.92
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