| Year |
Citation |
Score |
| 2024 |
Nitschke L, Hu RC, Miller AN, Cooper TA. Rescue of Scn5a mis-splicing does not improve the structural and functional heart defects of a DM1 heart mouse model. Human Molecular Genetics. PMID 39126705 DOI: 10.1093/hmg/ddae117 |
0.369 |
|
| 2023 |
Penna MS, Hu RC, Rodney GG, Cooper TA. The role of alternative splicing in skeletal muscle function. Life Science Alliance. 6. PMID 36977593 DOI: 10.26508/lsa.202201868 |
0.383 |
|
| 2021 |
Rao AN, Campbell HM, Guan X, Word TA, Wehrens XH, Xia Z, Cooper TA. Reversible cardiac disease features in an inducible CUG-repeat RNA expressing mouse model of myotonic dystrophy. Jci Insight. PMID 33497365 DOI: 10.1172/jci.insight.143465 |
0.428 |
|
| 2020 |
Johnson SJ, Cooper TA. Overlapping mechanisms of lncRNA and expanded microsatellite RNA. Wiley Interdisciplinary Reviews. Rna. e1634. PMID 33191580 DOI: 10.1002/wrna.1634 |
0.324 |
|
| 2020 |
Cox DC, Guan X, Xia Z, Cooper TA. Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting. Human Molecular Genetics. PMID 32412585 DOI: 10.1093/Hmg/Ddaa095 |
0.533 |
|
| 2020 |
Misra C, Bangru S, Lin F, Lam K, Koenig SN, Lubbers ER, Hedhli J, Murphy NP, Parker DJ, Dobrucki LW, Cooper TA, Tajkhorshid E, Mohler PJ, Kalsotra A. Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy. Developmental Cell. PMID 32109384 DOI: 10.1016/J.Devcel.2020.01.037 |
0.777 |
|
| 2019 |
Sharp L, Cox DC, Cooper TA. Endurance exercise leads to beneficial molecular and physiological effects in a mouse model of myotonic dystrophy type 1. Muscle & Nerve. PMID 31509256 DOI: 10.1002/Mus.26709 |
0.358 |
|
| 2018 |
Wang ET, Treacy D, Eichinger K, Struck A, Estabrook J, Olafson H, Wang TT, Bhatt K, Westbrook T, Sedehizadeh S, Ward A, Day J, Brook D, Berglund JA, Cooper T, et al. Transcriptome alterations in myotonic dystrophy skeletal muscle and heart. Human Molecular Genetics. PMID 30561649 DOI: 10.1093/Hmg/Ddy432 |
0.48 |
|
| 2018 |
Payer LM, Steranka JP, Ardeljan D, Walker J, Fitzgerald KC, Calabresi PA, Cooper TA, Burns KH. Alu insertion variants alter mRNA splicing. Nucleic Acids Research. PMID 30418605 DOI: 10.1093/Nar/Gky1086 |
0.395 |
|
| 2018 |
Pang PD, Alsina KM, Cao S, Koushik AB, Wehrens XHT, Cooper TA. CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias. Journal of the American Heart Association. 7: e010393. PMID 30371314 DOI: 10.1161/Jaha.118.010393 |
0.389 |
|
| 2018 |
Eric Blue R, Koushik A, Engels NM, Wiedner HJ, Cooper TA, Giudice J. Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology. The International Journal of Biochemistry & Cell Biology. PMID 30316870 DOI: 10.1016/J.Biocel.2018.10.004 |
0.498 |
|
| 2018 |
Singh RK, Kolonin AM, Fiorotto ML, Cooper TA. Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis. Cell Reports. 24: 197-208. PMID 29972780 DOI: 10.1016/J.Celrep.2018.06.017 |
0.455 |
|
| 2018 |
Morriss GR, Rajapakshe K, Huang S, Coarfa C, Cooper TA. Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1. Human Molecular Genetics. PMID 29771332 DOI: 10.1093/Hmg/Ddy192 |
0.481 |
|
| 2018 |
Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Correction: Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. Plos Biology. 16: e1002622. PMID 29509758 DOI: 10.1371/Journal.Pbio.1002622 |
0.583 |
|
| 2018 |
MISRA C, BANGRU S, PARKER DJ, KOENIG S, LUBBERS E, HEDHLI J, COOPER TA, DOBRUCKI WL, MOHLER P, KALSOTRA A. Abstract 520: Overexpression of a Non-muscle RBFOX2 Splice Isoform Induce Cardiac Arrhythmias in Myotonic Dystrophy Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.520 |
0.753 |
|
| 2017 |
Rao AN, Cooper TA. A Therapeutic Double Whammy: Transcriptional or Post-transcriptional Suppression of Microsatellite Repeat Toxicity by Cas9. Molecular Cell. 68: 473-475. PMID 29100050 DOI: 10.1016/J.Molcel.2017.10.023 |
0.329 |
|
| 2017 |
Manning KS, Rao AN, Castro M, Cooper TA. BNA(NC) gapmers revert splicing and reduce RNA foci with low toxicity in myotonic dystrophy cells. Acs Chemical Biology. PMID 28853853 DOI: 10.1021/Acschembio.7B00416 |
0.434 |
|
| 2017 |
Brinegar AE, Xia Z, Loehr JA, Li W, Rodney GG, Cooper TA. Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions. Elife. 6. PMID 28826478 DOI: 10.7554/Elife.27192 |
0.465 |
|
| 2017 |
Sharpe JJ, Cooper TA. Unexpected consequences: exon skipping caused by CRISPR-generated mutations. Genome Biology. 18: 109. PMID 28615035 DOI: 10.1186/S13059-017-1240-0 |
0.32 |
|
| 2017 |
Morriss GR, Cooper TA. Protein sequestration as a normal function of long noncoding RNAs and a pathogenic mechanism of RNAs containing nucleotide repeat expansions. Human Genetics. PMID 28484853 DOI: 10.1007/S00439-017-1807-6 |
0.46 |
|
| 2017 |
Brinegar AE, Xia Z, Loehr JA, Li W, Rodney GG, Cooper TA. Author response: Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions Elife. DOI: 10.7554/Elife.27192.025 |
0.361 |
|
| 2016 |
Giudice J, Loehr JA, Rodney GG, Cooper TA. Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology. Cell Reports. 17: 1923-1933. PMID 27851958 DOI: 10.1016/J.Celrep.2016.10.072 |
0.474 |
|
| 2016 |
Manning KS, Cooper TA. The roles of RNA processing in translating genotype to phenotype. Nature Reviews. Molecular Cell Biology. PMID 27847391 DOI: 10.1038/Nrm.2016.139 |
0.383 |
|
| 2016 |
Giudice J, Xia Z, Li W, Cooper TA. Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1. Scientific Reports. 6: 35550. PMID 27759042 DOI: 10.1038/Srep35550 |
0.513 |
|
| 2016 |
Brinegar AE, Cooper TA. Roles for RNA-binding proteins in development and disease. Brain Research. 1647: 1-8. PMID 26972534 DOI: 10.1016/J.Brainres.2016.02.050 |
0.45 |
|
| 2015 |
Hsu TY, Simon LM, Neill NJ, Marcotte R, Sayad A, Bland CS, Echeverria GV, Sun T, Kurley SJ, Tyagi S, Karlin KL, Dominguez-Vidaña R, Hartman JD, Renwick A, Scorsone K, ... ... Cooper TA, et al. The spliceosome is a therapeutic vulnerability in MYC-driven cancer. Nature. PMID 26331541 DOI: 10.1038/Nature14985 |
0.393 |
|
| 2015 |
Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. Plos Biology. 13: e1002197. PMID 26176594 DOI: 10.1371/Journal.Pbio.1002197 |
0.62 |
|
| 2015 |
Wang ET, Ward AJ, Cherone JM, Giudice J, Wang TT, Treacy DJ, Lambert NJ, Freese P, Saxena T, Cooper TA, Burge CB. Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins. Genome Research. 25: 858-71. PMID 25883322 DOI: 10.1101/Gr.184390.114 |
0.554 |
|
| 2015 |
Gennarino VA, Singh RK, White JJ, De Maio A, Han K, Kim JY, Jafar-Nejad P, di Ronza A, Kang H, Sayegh LS, Cooper TA, Orr HT, Sillitoe RV, Zoghbi HY. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 160: 1087-98. PMID 25768905 DOI: 10.1016/J.Cell.2015.02.012 |
0.366 |
|
| 2015 |
Pedrotti S, Giudice J, Dagnino-Acosta A, Knoblauch M, Singh RK, Hanna A, Mo Q, Hicks J, Hamilton S, Cooper TA. The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function. Human Molecular Genetics. 24: 2360-74. PMID 25575511 DOI: 10.1093/Hmg/Ddv003 |
0.49 |
|
| 2014 |
Xia Z, Donehower LA, Cooper TA, Neilson JR, Wheeler DA, Wagner EJ, Li W. Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3'-UTR landscape across seven tumour types. Nature Communications. 5: 5274. PMID 25409906 DOI: 10.1038/Ncomms6274 |
0.37 |
|
| 2014 |
Giudice J, Cooper TA. RNA-binding proteins in heart development. Advances in Experimental Medicine and Biology. 825: 389-429. PMID 25201112 DOI: 10.1007/978-1-4939-1221-6_11 |
0.462 |
|
| 2014 |
Singh RK, Xia Z, Bland CS, Kalsotra A, Scavuzzo MA, Curk T, Ule J, Li W, Cooper TA. Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis. Molecular Cell. 55: 592-603. PMID 25087874 DOI: 10.1016/J.Molcel.2014.06.035 |
0.718 |
|
| 2014 |
Giudice J, Xia Z, Wang ET, Scavuzzo MA, Ward AJ, Kalsotra A, Wang W, Wehrens XH, Burge CB, Li W, Cooper TA. Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development. Nature Communications. 5: 3603. PMID 24752171 DOI: 10.1038/Ncomms4603 |
0.72 |
|
| 2014 |
Pedrotti S, Cooper TA. In Brief: (mis)splicing in disease. The Journal of Pathology. 233: 1-3. PMID 24615176 DOI: 10.1002/Path.4337 |
0.409 |
|
| 2014 |
Kalsotra A, Singh RK, Gurha P, Ward AJ, Creighton CJ, Cooper TA. The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression. Cell Reports. 6: 336-45. PMID 24412363 DOI: 10.1016/J.Celrep.2013.12.025 |
0.646 |
|
| 2014 |
Echeverria GV, Cooper TA. Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron Nucleic Acids Research. 42: 1893-1903. PMID 24185704 DOI: 10.1093/Nar/Gkt1020 |
0.407 |
|
| 2013 |
Gao Z, Cooper TA. Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: 13570-5. PMID 23901116 DOI: 10.1073/Pnas.1308806110 |
0.448 |
|
| 2013 |
Gao Z, Cooper TA. Antisense oligonucleotides: rising stars in eliminating RNA toxicity in myotonic dystrophy. Human Gene Therapy. 24: 499-507. PMID 23252746 DOI: 10.1089/Hum.2012.212 |
0.423 |
|
| 2012 |
Cooper TA. Implications of widespread covalent modification of mRNA. Circulation Research. 111: 1491-3. PMID 23223930 DOI: 10.1161/Circresaha.112.281071 |
0.43 |
|
| 2012 |
Singh RK, Cooper TA. Pre-mRNA splicing in disease and therapeutics. Trends in Molecular Medicine. 18: 472-82. PMID 22819011 DOI: 10.1016/J.Molmed.2012.06.006 |
0.381 |
|
| 2012 |
Echeverria GV, Cooper TA. RNA-binding proteins in microsatellite expansion disorders: mediators of RNA toxicity. Brain Research. 1462: 100-11. PMID 22405728 DOI: 10.1016/J.Brainres.2012.02.030 |
0.433 |
|
| 2012 |
Lee JE, Bennett CF, Cooper TA. RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1 Proceedings of the National Academy of Sciences of the United States of America. 109: 4221-4226. PMID 22371589 DOI: 10.1073/Pnas.1117019109 |
0.461 |
|
| 2011 |
Kalsotra A, Cooper TA. Functional consequences of developmentally regulated alternative splicing. Nature Reviews. Genetics. 12: 715-29. PMID 21921927 DOI: 10.1038/Nrg3052 |
0.698 |
|
| 2011 |
Cooper TA. Regulating mRNA complexity in the mammalian brain. Nature Genetics. 43: 618-9. PMID 21847796 DOI: 10.1038/Ng.867 |
0.365 |
|
| 2011 |
Gomes-Pereira M, Cooper TA, Gourdon G. Myotonic dystrophy mouse models: towards rational therapy development. Trends in Molecular Medicine. 17: 506-17. PMID 21724467 DOI: 10.1016/J.Molmed.2011.05.004 |
0.365 |
|
| 2011 |
Orengo JP, Ward AJ, Cooper TA. Alternative splicing dysregulation secondary to skeletal muscle regeneration Annals of Neurology. 69: 681-690. PMID 21400563 DOI: 10.1002/Ana.22278 |
0.511 |
|
| 2011 |
Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, et al. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 3665-70. PMID 21307310 DOI: 10.1073/Pnas.1019736108 |
0.349 |
|
| 2011 |
Grammatikakis I, Goo YH, Echeverria GV, Cooper TA. Identification of MBNL1 and MBNL3 domains required for splicing activation and repression. Nucleic Acids Research. 39: 2769-80. PMID 21109529 DOI: 10.1093/Nar/Gkq1155 |
0.448 |
|
| 2010 |
Bland CS, Wang ET, Vu A, David MP, Castle JC, Johnson JM, Burge CB, Cooper TA. Global regulation of alternative splicing during myogenic differentiation Nucleic Acids Research. 38: 7651-7664. PMID 20634200 DOI: 10.1093/Nar/Gkq614 |
0.409 |
|
| 2010 |
Ward AJ, Rimer M, Killian JM, Dowling JJ, Cooper TA. CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1. Human Molecular Genetics. 19: 3614-22. PMID 20603324 DOI: 10.1093/Hmg/Ddq277 |
0.463 |
|
| 2010 |
Kalsotra A, Wang K, Li PF, Cooper TA. MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development. Genes & Development. 24: 653-8. PMID 20299448 DOI: 10.1101/Gad.1894310 |
0.675 |
|
| 2010 |
Koshelev M, Sarma S, Price RE, Wehrens XHT, Cooper TA. Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1 Human Molecular Genetics. 19: 1066-1075. PMID 20051426 DOI: 10.1093/Hmg/Ddp570 |
0.529 |
|
| 2010 |
Ward AJ, Cooper TA. The pathobiology of splicing Journal of Pathology. 220: 152-163. PMID 19918805 DOI: 10.1002/Path.2649 |
0.464 |
|
| 2009 |
Lee JE, Cooper TA. Pathogenic mechanisms of myotonic dystrophy Biochemical Society Transactions. 37: 1281-1286. PMID 19909263 DOI: 10.1042/Bst0371281 |
0.471 |
|
| 2009 |
Wang GS, Kuyumcu-Martinez MN, Sarma S, Mathur N, Wehrens XH, Cooper TA. PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1. The Journal of Clinical Investigation. 119: 3797-806. PMID 19907076 DOI: 10.1172/Jci37976 |
0.429 |
|
| 2009 |
Cooper TA. Chemical reversal of the RNA gain of function in myotonic dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 106: 18433-4. PMID 19864622 DOI: 10.1073/Pnas.0910643106 |
0.449 |
|
| 2009 |
Cooper TA. Molecular biology. Neutralizing toxic RNA. Science (New York, N.Y.). 325: 272-3. PMID 19608901 DOI: 10.1126/Science.1177452 |
0.409 |
|
| 2009 |
Goo YH, Cooper TA. CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. Nucleic Acids Research. 37: 4275-86. PMID 19443441 DOI: 10.1093/Nar/Gkp346 |
0.352 |
|
| 2009 |
Cooper TA, Wan L, Dreyfuss G. RNA and disease. Cell. 136: 777-93. PMID 19239895 DOI: 10.1016/J.Cell.2009.02.011 |
0.426 |
|
| 2008 |
Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA. A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart Proceedings of the National Academy of Sciences of the United States of America. 105: 20333-20338. PMID 19075228 DOI: 10.1073/Pnas.0809045105 |
0.696 |
|
| 2008 |
Castle JC, Zhang C, Shah JK, Kulkarni AV, Kalsotra A, Cooper TA, Johnson JM. Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines. Nature Genetics. 40: 1416-25. PMID 18978788 DOI: 10.1038/Ng.264 |
0.712 |
|
| 2008 |
Orengo JP, Chambon P, Metzger D, Mosier DR, Snipes GJ, Cooper TA. Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 105: 2646-51. PMID 18272483 DOI: 10.1073/Pnas.0708519105 |
0.477 |
|
| 2008 |
Dhaenens CM, Schraen-Maschke S, Tran H, Vingtdeux V, Ghanem D, Leroy O, Delplanque J, Vanbrussel E, Delacourte A, Vermersch P, Maurage CA, Gruffat H, Sergeant A, Mahadevan MS, Ishiura S, ... ... Cooper TA, et al. Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: two individual consequences of CUG trinucleotide repeats. Experimental Neurology. 210: 467-78. PMID 18177861 DOI: 10.1016/J.Expneurol.2007.11.020 |
0.41 |
|
| 2007 |
Orengo JP, Cooper TA. Alternative splicing in disease. Advances in Experimental Medicine and Biology. 623: 212-23. PMID 18380349 DOI: 10.1007/978-0-387-77374-2_13 |
0.411 |
|
| 2007 |
Kuyumcu-Martinez NM, Wang GS, Cooper TA. Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation. Molecular Cell. 28: 68-78. PMID 17936705 DOI: 10.1016/J.Molcel.2007.07.027 |
0.495 |
|
| 2007 |
Wang GS, Kearney DL, De Biasi M, Taffet G, Cooper TA. Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy. The Journal of Clinical Investigation. 117: 2802-11. PMID 17823658 DOI: 10.1172/Jci32308 |
0.518 |
|
| 2007 |
Wang GS, Cooper TA. Splicing in disease: disruption of the splicing code and the decoding machinery. Nature Reviews. Genetics. 8: 749-61. PMID 17726481 DOI: 10.1038/Nrg2164 |
0.407 |
|
| 2007 |
Chapple JP, Anthony K, Martin TR, Dev A, Cooper TA, Gallo JM. Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4. Human Molecular Genetics. 16: 2760-9. PMID 17725984 DOI: 10.1093/Hmg/Ddm233 |
0.438 |
|
| 2007 |
Bland CS, Cooper TA. Micromanaging Alternative Splicing during Muscle Differentiation Developmental Cell. 12: 171-172. PMID 17276332 DOI: 10.1016/J.Devcel.2007.01.014 |
0.408 |
|
| 2006 |
Orengo JP, Bundman D, Cooper TA. A bichromatic fluorescent reporter for cell-based screens of alternative splicing. Nucleic Acids Research. 34: e148. PMID 17142220 DOI: 10.1093/Nar/Gkl967 |
0.381 |
|
| 2006 |
Kuyumcu-Martinez NM, Cooper TA. Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy. Progress in Molecular and Subcellular Biology. 44: 133-59. PMID 17076268 DOI: 10.1007/978-3-540-34449-0_7 |
0.522 |
|
| 2006 |
Cooper TA. A reversal of misfortune for myotonic dystrophy? The New England Journal of Medicine. 355: 1825-7. PMID 17065646 DOI: 10.1056/Nejmcibr064708 |
0.397 |
|
| 2006 |
Singh G, Cooper TA. Minigene reporter for identification and analysis of cis elements and trans factors affecting pre-mRNA splicing. Biotechniques. 41: 177-81. PMID 16925019 DOI: 10.2144/000112208 |
0.469 |
|
| 2006 |
Ranum LP, Cooper TA. RNA-mediated neuromuscular disorders. Annual Review of Neuroscience. 29: 259-77. PMID 16776586 DOI: 10.1146/Annurev.Neuro.29.051605.113014 |
0.428 |
|
| 2006 |
de Haro M, Al-Ramahi I, De Gouyon B, Ukani L, Rosa A, Faustino NA, Ashizawa T, Cooper TA, Botas J. MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1. Human Molecular Genetics. 15: 2138-45. PMID 16723374 DOI: 10.1093/Hmg/Ddl137 |
0.485 |
|
| 2006 |
Leroy O, Wang J, Maurage CA, Parent M, Cooper T, Buée L, Sergeant N, Andreadis A, Caillet-Boudin ML. Brain-specific change in alternative splicing of Tau exon 6 in myotonic dystrophy type 1. Biochimica Et Biophysica Acta. 1762: 460-7. PMID 16487687 DOI: 10.1016/J.Bbadis.2005.12.003 |
0.445 |
|
| 2006 |
Thornton CA, Swanson MS, Cooper TA. The RNA-mediated disease process in myotonic dystrophy Genetic Instabilities and Neurological Diseases, Second Edition. 37-54. DOI: 10.1016/B978-012369462-1/50004-1 |
0.344 |
|
| 2005 |
Cooper TA. Use of minigene systems to dissect alternative splicing elements. Methods (San Diego, Calif.). 37: 331-40. PMID 16314262 DOI: 10.1016/J.Ymeth.2005.07.015 |
0.407 |
|
| 2005 |
Ladd AN, Taffet G, Hartley C, Kearney DL, Cooper TA. Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Molecular and Cellular Biology. 25: 6267-78. PMID 15988035 DOI: 10.1128/Mcb.25.14.6267-6278.2005 |
0.56 |
|
| 2005 |
Ho TH, Savkur RS, Poulos MG, Mancini MA, Swanson MS, Cooper TA. Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. Journal of Cell Science. 118: 2923-33. PMID 15961406 DOI: 10.1242/Jcs.02404 |
0.488 |
|
| 2005 |
Han J, Cooper TA. Identification of CELF splicing activation and repression domains in vivo. Nucleic Acids Research. 33: 2769-80. PMID 15894795 DOI: 10.1093/Nar/Gki561 |
0.367 |
|
| 2005 |
Ho TH, Bundman D, Armstrong DL, Cooper TA. Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy. Human Molecular Genetics. 14: 1539-47. PMID 15843400 DOI: 10.1093/Hmg/Ddi162 |
0.513 |
|
| 2005 |
Ladd AN, Stenberg MG, Swanson MS, Cooper TA. Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development Developmental Dynamics. 233: 783-793. PMID 15830352 DOI: 10.1002/Dvdy.20382 |
0.481 |
|
| 2005 |
Faustino NA, Cooper TA. Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment. Molecular and Cellular Biology. 25: 879-87. PMID 15657417 DOI: 10.1128/Mcb.25.3.879-887.2005 |
0.412 |
|
| 2005 |
Cooper TA. Alternative splicing regulation impacts heart development. Cell. 120: 1-2. PMID 15652472 DOI: 10.1016/J.Cell.2004.12.030 |
0.445 |
|
| 2004 |
Ho TH, Charlet-B N, Poulos MG, Singh G, Swanson MS, Cooper TA. Muscleblind proteins regulate alternative splicing. The Embo Journal. 23: 3103-12. PMID 15257297 DOI: 10.1038/Sj.Emboj.7600300 |
0.479 |
|
| 2004 |
Ladd AN, Cooper TA. Multiple domains control the subcellular localization and activity of ETR-3, a regulator of nuclear and cytoplasmic RNA processing events. Journal of Cell Science. 117: 3519-29. PMID 15226369 DOI: 10.1242/Jcs.01194 |
0.43 |
|
| 2004 |
Savkur RS, Philips AV, Cooper TA, Dalton JC, Moseley ML, Ranum LP, Day JW. Insulin receptor splicing alteration in myotonic dystrophy type 2. American Journal of Human Genetics. 74: 1309-13. PMID 15114529 DOI: 10.1086/421528 |
0.437 |
|
| 2004 |
Singh G, Charlet-B N, Han J, Cooper TA. ETR-3 and CELF4 protein domains required for RNA binding and splicing activity in vivo. Nucleic Acids Research. 32: 1232-41. PMID 14973222 DOI: 10.1093/Nar/Gkh275 |
0.413 |
|
| 2004 |
Ladd AN, Nguyen NH, Malhotra K, Cooper TA. CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing. The Journal of Biological Chemistry. 279: 17756-64. PMID 14761971 DOI: 10.1074/Jbc.M310687200 |
0.494 |
|
| 2003 |
Gromak N, Matlin AJ, Cooper TA, Smith CW. Antagonistic regulation of alpha-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein. Rna (New York, N.Y.). 9: 443-56. PMID 12649496 DOI: 10.1261/Rna.2191903 |
0.416 |
|
| 2003 |
Faustino NA, Cooper TA. Pre-mRNA splicing and human disease. Genes & Development. 17: 419-37. PMID 12600935 DOI: 10.1101/Gad.1048803 |
0.392 |
|
| 2002 |
Ladd AN, Cooper TA. Finding signals that regulate alternative splicing in the post-genomic era. Genome Biology. 3: reviews0008. PMID 12429065 DOI: 10.1186/Gb-2002-3-11-Reviews0008 |
0.379 |
|
| 2002 |
Charlet-B N, Savkur RS, Singh G, Philips AV, Grice EA, Cooper TA. Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing. Molecular Cell. 10: 45-53. PMID 12150906 DOI: 10.1016/S1097-2765(02)00572-5 |
0.464 |
|
| 2002 |
Charlet-B N, Logan P, Singh G, Cooper TA. Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Molecular Cell. 9: 649-58. PMID 11931771 DOI: 10.1016/S1097-2765(02)00479-3 |
0.425 |
|
| 2001 |
Cooper TA. Highlights of alternative splicing regulation session: yes, no, maybe--a history of paradigm shifts. Science Signaling. 2001. PMID 11675513 DOI: 10.1126/Stke.2001.105.Pe35 |
0.452 |
|
| 2001 |
Savkur RS, Philips AV, Cooper TA. Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy Nature Genetics. 29: 40-47. PMID 11528389 DOI: 10.1038/Ng704 |
0.407 |
|
| 2001 |
Stickeler E, Fraser SD, Honig A, Chen AL, Berget SM, Cooper TA. The RNA binding protein YB‐1 binds A/C‐rich exon enhancers and stimulates splicing of the CD44 alternative exon v4 The Embo Journal. 20: 3821-3830. PMID 11447123 DOI: 10.1093/Emboj/20.14.3821 |
0.401 |
|
| 2001 |
Ladd AN, Charlet N, Cooper TA. The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Molecular and Cellular Biology. 21: 1285-96. PMID 11158314 DOI: 10.1128/Mcb.21.4.1285-1296.2001 |
0.548 |
|
| 2000 |
Ryan KJ, Charlet-B. N, Cooper TA. Binding of purH to a muscle-specific splicing enhancer functionally correlates with exon inclusion in vivo Journal of Biological Chemistry. 275: 20618-20626. PMID 10801888 DOI: 10.1074/Jbc.M909977199 |
0.481 |
|
| 2000 |
Philips AV, Cooper TA. RNA processing and human disease. Cellular and Molecular Life Sciences : Cmls. 57: 235-49. PMID 10766020 DOI: 10.1007/PL00000687 |
0.36 |
|
| 2000 |
Ashizawa T, Gonzales I, Ohsawa N, Singer RH, Devillers M, Balasubramanyam A, Cooper TA, Khajavi M, Lia-Baldini AS, Miller G, Philips AV, Timchenko LT, Waring J, Yamagata H, Barbet JP, et al. New nomenclature and DNA testing guidelines for myotonic dystrophy type 1 (DM1) Neurology. 54: 1218-1221. PMID 10746587 DOI: 10.1212/Wnl.54.6.1218 |
0.325 |
|
| 1999 |
Cooper TA. Defining pre-mRNA cis elements that regulate cell-specific splicing. Methods of Molecular Biology. 118: 391-403. PMID 10549538 DOI: 10.1385/1-59259-676-2:391 |
0.35 |
|
| 1999 |
Stark JM, Cooper TA, Roth MB. The relative strengths of SR protein-mediated associations of alternative and constitutive exons can influence alternative splicing Journal of Biological Chemistry. 274: 29838-29842. PMID 10514463 DOI: 10.1074/Jbc.274.42.29838 |
0.427 |
|
| 1999 |
Stoss O, Schwaiger F, Cooper TA, Stamm S. Alternative Splicing Determines The Intracellular Localization Of The Novel Nuclear Protein Nop30 And Its Interaction With The Splicing Factor Srp30C Journal of Biological Chemistry. 274: 10951-10962. PMID 10196175 DOI: 10.1074/Jbc.274.16.10951 |
0.422 |
|
| 1998 |
Cooper TA. Muscle-specific splicing of a heterologous exon mediated by a single muscle-specific splicing enhancer from the cardiac troponin T gene. Molecular and Cellular Biology. 18: 4519-4525. PMID 9671461 DOI: 10.1128/Mcb.18.8.4519 |
0.459 |
|
| 1998 |
Philips AV, Timchenko LT, Cooper TA. Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy Science. 280: 737-741. PMID 9563950 DOI: 10.1126/Science.280.5364.737 |
0.536 |
|
| 1998 |
Elrick LL, Humphrey MB, Cooper TA, Berget SM. A short sequence within two purine-rich enhancers determines 5' splice site specificity. Molecular and Cellular Biology. 18: 343-52. PMID 9418881 DOI: 10.1128/Mcb.18.1.343 |
0.359 |
|
| 1997 |
Cooper TA, Mattox W. The regulation of splice-site selection, and its role in human disease. American Journal of Human Genetics. 61: 259-66. PMID 9311728 DOI: 10.1086/514856 |
0.328 |
|
| 1997 |
Coulter LR, Landree MA, Cooper TA. Identification of a new class of exonic splicing enhancers by in vivo selection. Molecular and Cellular Biology. 17: 2143-2150. PMID 9121463 DOI: 10.1128/Mcb.17.4.2143 |
0.439 |
|
| 1996 |
Ryan KJ, Cooper TA. Muscle-specific splicing enhancers regulate inclusion of the cardiac troponin T alternative exon in embryonic skeletal muscle Molecular and Cellular Biology. 16: 4014-4023. PMID 8754799 DOI: 10.1128/Mcb.16.8.4014 |
0.501 |
|
| 1995 |
Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA. A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer Molecular and Cellular Biology. 15: 4898-4907. PMID 7651409 DOI: 10.1128/Mcb.15.9.4898 |
0.47 |
|
| 1995 |
Humphrey MB, Bryan J, Cooper TA, Berget SM. A 32-nucleotide exon-splicing enhancer regulates usage of competing 5' splice sites in a differential internal exon Molecular and Cellular Biology. 15: 3979-3988. PMID 7623794 DOI: 10.1128/Mcb.15.8.3979 |
0.394 |
|
| 1993 |
Xu R, Teng J, Cooper TA. The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element Molecular and Cellular Biology. 13: 3660-3674. PMID 8388541 DOI: 10.1128/Mcb.13.6.3660 |
0.452 |
|
| 1989 |
Cooper TA, Ordahl CP. Nucleotide substitutions within the cardiac troponin T alternative exon disrupt pre-mRNA alternative splicing Nucleic Acids Research. 17: 7905-7921. PMID 2798134 DOI: 10.1093/Nar/17.19.7905 |
0.424 |
|
| 1988 |
Cooper TA, Cardone MH, Ordahl CP. Cis requirements for alternative splicing of the cardiac troponin T pre–mRNA Nucleic Acids Research. 16: 8443-8465. PMID 3419923 DOI: 10.1093/Nar/16.17.8443 |
0.453 |
|
| 1988 |
Mar JH, Antin PB, Cooper TA, Ordahl CP. Analysis of the upstream regions governing expression of the chicken cardiac troponin T gene in embryonic cardiac and skeletal muscle cells Journal of Cell Biology. 107: 573-585. PMID 3047142 DOI: 10.1083/Jcb.107.2.573 |
0.357 |
|
| 1984 |
Cooper TA, Ordahl CP. A single troponin T gene regulated by different programs in cardiac and skeletal muscle development. Science. 226: 979-982. PMID 6095446 DOI: 10.1126/Science.6095446 |
0.467 |
|
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