| Year |
Citation |
Score |
| 2023 |
Anwar AF, Cain CF, Garza MJ, Degen D, Ebright RH, Del Valle JR. Stabilizing pseudouridimycin: Synthesis, RNA-polymerase inhibitory activity, and antibacterial activity of dipeptide-modified analogues. Chemmedchem. e202300474. PMID 37751316 DOI: 10.1002/cmdc.202300474 |
0.664 |
|
| 2022 |
Elbatrawi YM, Gerrein T, Anwar A, Makwana KM, Degen D, Ebright RH, Del Valle JR. Total Synthesis of Pargamicin A. Organic Letters. PMID 36516292 DOI: 10.1021/acs.orglett.2c03861 |
0.541 |
|
| 2022 |
Hassan HM, Degen D, Jang KH, Ebright RH, Fenical W. Correction to: Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp. The Journal of Antibiotics. PMID 35546183 DOI: 10.1038/s41429-022-00528-4 |
0.613 |
|
| 2019 |
Lin W, Mandal S, Degen D, Cho MS, Feng Y, Das K, Ebright RH. Structural basis of ECF-σ-factor-dependent transcription initiation. Nature Communications. 10: 710. PMID 30755604 DOI: 10.1038/s41467-019-08443-3 |
0.725 |
|
| 2019 |
Lin W, Mandal S, Degen D, Cho, Feng Y, Das K, Ebright RH. Structural basis of ECF-sigma-factor-dependent transcription initiation. Nature Communications. 10: 710-710. DOI: 10.2210/Pdb6Dv9/Pdb |
0.753 |
|
| 2018 |
Lin W, Das K, Degen D, Mazumder A, Duchi D, Wang D, Ebright YW, Ebright RY, Sineva E, Gigliotti M, Srivastava A, Mandal S, Jiang Y, Liu Y, Yin R, et al. Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Molecular Cell. PMID 29606590 DOI: 10.1016/J.Molcel.2018.02.026 |
0.688 |
|
| 2017 |
Maffioli SI, Zhang Y, Degen D, Carzaniga T, Del Gatto G, Serina S, Monciardini P, Mazzetti C, Guglierame P, Candiani G, Chiriac AI, Facchetti G, Kaltofen P, Sahl HG, Dehò G, et al. Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell. 169: 1240-1248.e23. PMID 28622509 DOI: 10.1016/J.Cell.2017.05.042 |
0.713 |
|
| 2017 |
Lin W, Mandal S, Degen D, Liu Y, Ebright YW, Li S, Feng Y, Zhang Y, Mandal S, Jiang Y, Liu S, Gigliotti M, Talaue M, Connell N, Das K, et al. Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Molecular Cell. PMID 28392175 DOI: 10.1016/J.Molcel.2017.03.001 |
0.797 |
|
| 2017 |
Walker SS, Degen D, Nickbarg E, Carr D, Soriano A, Mandal MB, Painter RE, Sheth PR, Xiao L, Sher X, Murgolo N, Su J, Olsen DB, Ebright RH, Young K. Affinity Selection-Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor. Acs Chemical Biology. PMID 28323406 DOI: 10.1021/Acschembio.6B01133 |
0.686 |
|
| 2015 |
Feng Y, Degen D, Wang X, Gigliotti M, Liu S, Zhang Y, Das D, Michalchuk T, Ebright YW, Talaue M, Connell N, Ebright RH. Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure (London, England : 1993). PMID 26190576 DOI: 10.1016/J.Str.2015.06.009 |
0.751 |
|
| 2015 |
Hassan HM, Degen D, Jang KH, Ebright RH, Fenical W. Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp. The Journal of Antibiotics. 68: 206-9. PMID 25227504 DOI: 10.1038/Ja.2014.122 |
0.649 |
|
| 2015 |
Feng Y, Degen D, Wang X, Gigliotti M, Liu S, Zhang Y, Das D, Michalchuk T, Ebright YW, Talaue M, Connell N, Ebright RH. Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles Structure. DOI: 10.1016/j.str.2015.06.009 |
0.621 |
|
| 2014 |
Tang W, Liu S, Degen D, Ebright RH, Prusov EV. Synthesis and evaluation of novel analogues of ripostatins. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 12310-9. PMID 25112727 DOI: 10.1002/Chem.201403176 |
0.638 |
|
| 2014 |
Degen D, Feng Y, Zhang Y, Ebright KY, Ebright YW, Gigliotti M, Vahedian-Movahed H, Mandal S, Talaue M, Connell N, Arnold E, Fenical W, Ebright RH. Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife. 3: e02451. PMID 24843001 DOI: 10.7554/Elife.02451 |
0.808 |
|
| 2014 |
Zhang Y, Degen D, Ho MX, Sineva E, Ebright KY, Ebright YW, Mekler V, Vahedian-Movahed H, Feng Y, Yin R, Tuske S, Irschik H, Jansen R, Maffioli S, Donadio S, et al. GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife. 3: e02450. PMID 24755292 DOI: 10.7554/Elife.02450 |
0.775 |
|
| 2012 |
Srivastava A, Degen D, Ebright YW, Ebright RH. Frequency, spectrum, and nonzero fitness costs of resistance to myxopyronin in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 56: 6250-5. PMID 23006749 DOI: 10.1128/Aac.01060-12 |
0.609 |
|
| 2011 |
Srivastava A, Talaue M, Liu S, Degen D, Ebright RY, Sineva E, Chakraborty A, Druzhinin SY, Chatterjee S, Mukhopadhyay J, Ebright YW, Zozula A, Shen J, Sengupta S, Niedfeldt RR, et al. New target for inhibition of bacterial RNA polymerase: 'switch region'. Current Opinion in Microbiology. 14: 532-43. PMID 21862392 DOI: 10.1016/J.Mib.2011.07.030 |
0.639 |
|
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